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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4eh7IRGMitogen-activated protein kinase 14

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4eh7IRGMitogen-activated protein kinase 14/1.000
4eh4IRGMitogen-activated protein kinase 14/0.673
4dliIRGMitogen-activated protein kinase 14/0.637
4eh5IRGMitogen-activated protein kinase 14/0.633
4eh2IRGMitogen-activated protein kinase 14/0.612
4eh8IRGMitogen-activated protein kinase 14/0.610
3hl7I46Mitogen-activated protein kinase 14/0.578
4eh6IRGMitogen-activated protein kinase 14/0.568
3k3iI46Mitogen-activated protein kinase 14/0.563
4eh3IRGMitogen-activated protein kinase 14/0.549
3k3jI46Mitogen-activated protein kinase 14/0.539
2yisI46Mitogen-activated protein kinase 14/0.534
3hllI46Mitogen-activated protein kinase 14/0.533
3new3NEMitogen-activated protein kinase 14/0.528
4zthGG5Mitogen-activated protein kinase 14/0.527
2vmyFFOSerine hydroxymethyltransferase/0.517
3roc29BMitogen-activated protein kinase 14/0.515
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.514
4fnyI3KALK tyrosine kinase receptor2.7.10.10.504
4epq0RRPoly(ADP-ribose) glycohydrolase/0.503
1kl2FONSerine hydroxymethyltransferase/0.502
2itpAEEEpidermal growth factor receptor2.7.10.10.500
1d6w00RProthrombin3.4.21.50.497
3h3sH15Collagen type IV alpha-3-binding protein/0.496
1suiFRECaffeoyl-CoA O-methyltransferase2.1.1.1040.493
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.493
3e5aVX6Aurora kinase A2.7.11.10.492
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.491
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.491
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.490
1ypjUIBProthrombin3.4.21.50.489
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.489
3hub469Mitogen-activated protein kinase 14/0.485
3l0lHC3Nuclear receptor ROR-gamma/0.485
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.485
4y8vADPAcyl-CoA synthetase (NDP forming)/0.485
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.483
2bvs2CEProthrombin3.4.21.50.483
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.483
3uk6ADPRuvB-like 23.6.4.120.483
3v76FDAUncharacterized protein/0.483
4jauADPSensor histidine kinase/0.483
1hvyD16Thymidylate synthase2.1.1.450.481
2jh0701Prothrombin3.4.21.50.481
1d3dBZTProthrombin3.4.21.50.480
1ypeUIPProthrombin3.4.21.50.480
1oc1ASVIsopenicillin N synthase1.21.3.10.478
1wn3HXCPhenylacetic acid degradation protein PaaI/0.478
2cn0F25Prothrombin3.4.21.50.478
2gdeSN3Prothrombin3.4.21.50.478
4kwi1TJReductase homolog/0.478
4o701QKBromodomain-containing protein 4/0.478
1bucFADAcyl-CoA dehydrogenase, short-chain specific1.3.8.10.477
3zsh469Mitogen-activated protein kinase 14/0.477
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.476
2dvlFADAcyl-CoA dehydrogenase/0.476
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.476
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.476
1aiqCB3Thymidylate synthase/0.475
1oytFSNProthrombin3.4.21.50.475
1y4sADPChaperone protein HtpG/0.475
2xw7NDPDihydrofolate reductase/0.475
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.475
3il1B5DGlutamate receptor 2/0.475
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.475
3w0pADPHygromycin-B 4-O-kinase2.7.1.1630.475
4r20AERCytochrome P450 family 17 polypeptide 2/0.475
1synF89Thymidylate synthase/0.474
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
4pd6URINucleoside permease/0.474
1t1sCBQ1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.473
2anmCDOProthrombin3.4.21.50.473
2bdyUNBProthrombin3.4.21.50.473
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.473
3o6o94MHeat shock protein 83/0.473
4f9yGG5Mitogen-activated protein kinase 14/0.473
4r3cGG5Mitogen-activated protein kinase 14/0.473
1kekHTLPyruvate synthase/0.472
1z6tADPApoptotic protease-activating factor 1/0.472
1zdwFLVPrenyltransferase/0.472
3tdaPN0Cytochrome P450 2D6/0.472
4gub0Y4Casein kinase II subunit alpha2.7.11.10.472
4u2lSFDCholesterol oxidase1.1.3.60.472
2ydfIO3Serum albumin/0.471
4ayv9MQProthrombin3.4.21.50.471
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.471
4jx1CAHCamphor 5-monooxygenase1.14.15.10.471
1blzACVIsopenicillin N synthase1.21.3.10.470
1bwlFMNNADPH dehydrogenase 11.6.99.10.470
1obnASVIsopenicillin N synthase1.21.3.10.470
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.470
2cf9348Prothrombin3.4.21.50.470
3r83Z14Cyclin-dependent kinase 22.7.11.220.470
4ryvZEAProtein LlR18A/0.470
4uyf73BBromodomain-containing protein 2/0.470
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.469
3vt7VDXVitamin D3 receptor/0.469
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.469
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.469
1jutLYDThymidylate synthase/0.468
1xm1GAHProthrombin3.4.21.50.468
2igoFADPyranose 2-oxidase/0.468
3adaNADSubunit alpha of sarocosine oxidase/0.468
3ln1CELProstaglandin G/H synthase 21.14.99.10.468
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.468
3t8vBTJM1 family aminopeptidase3.4.110.468
3w2eNADNADH-cytochrome b5 reductase 31.6.2.20.468
4jx1CAMCamphor 5-monooxygenase1.14.15.10.468
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.468
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.468
1afeALZProthrombin3.4.21.50.467
1dhrNADDihydropteridine reductase1.5.1.340.467
2cf8ESHProthrombin3.4.21.50.467
2hamC33Vitamin D3 receptor/0.467
2xulATPNitrogen regulatory protein P-II/0.467
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.467
4ayy9MXProthrombin3.4.21.50.467
4l8u9AZSerum albumin/0.467
1ae8AZLProthrombin3.4.21.50.466
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
2vcwZZAHematopoietic prostaglandin D synthase/0.466
2zb8IMNProstaglandin reductase 21.3.1.480.466
3gb4D3MDdmC/0.466
3mqe416Prostaglandin G/H synthase 21.14.99.10.466
4gqiM49Ribosyldihydronicotinamide dehydrogenase [quinone]/0.466
4mwhATPCasein kinase II subunit alpha2.7.11.10.466
4nfhPFBAlcohol dehydrogenase E chain1.1.1.10.466
4tl8AGSCircadian clock protein kinase KaiC2.7.11.10.466
1d9i00PProthrombin3.4.21.50.465
1nm6L86Prothrombin3.4.21.50.465
2b7aIZATyrosine-protein kinase JAK2/0.465
2vcmM11Isopenicillin N synthase1.21.3.10.465
3oev3OEProteasome subunit beta type-53.4.25.10.465
3oev3OEProteasome subunit beta type-63.4.25.10.465
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.465
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.465
4g2fC07Ephrin type-A receptor 32.7.10.10.465
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.465
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.465
5c77SAHProtein arginine N-methyltransferase SFM1/0.465
5f54TMPSingle-stranded-DNA-specific exonuclease/0.465
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.464
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.464
2r1rTTPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.464
3oom507Activin receptor type-12.7.11.300.464
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.464
1ove358Mitogen-activated protein kinase 14/0.463
1vzqSHYProthrombin3.4.21.50.463
1zgv501Prothrombin3.4.21.50.463
2j4z626Aurora kinase A2.7.11.10.463
2jh5895Prothrombin3.4.21.50.463
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.463
2pg0FADAcyl-CoA dehydrogenase/0.463
2vbdV10Isopenicillin N synthase1.21.3.10.463
3r4pFU7Heat shock protein HSP 90-alpha/0.463
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.463
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.463
4n3l2FNProthrombin3.4.21.50.463
4twpAXITyrosine-protein kinase ABL12.7.10.20.463
4uugPXGBranched-chain amino acid aminotransferase, putative/0.463
4xwrFADCholesterol oxidase1.1.3.60.463
1ao05GPAmidophosphoribosyltransferase/0.462
1dnpMHFDeoxyribodipyrimidine photo-lyase4.1.99.30.462
1ijhFADCholesterol oxidase1.1.3.60.462
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
1kzjCB3Thymidylate synthase/0.462
1p0fNAPNADP-dependent alcohol dehydrogenase1.1.1.20.462
1sb1165Prothrombin3.4.21.50.462
1ypgUIRProthrombin3.4.21.50.462
2dw4FADLysine-specific histone demethylase 1A10.462
2gjlFMNNitronate monooxygenase1.13.12.160.462
2ywlFADThioredoxin reductase related protein/0.462
3c1kT15Prothrombin3.4.21.50.462
3m08RARDihydrofolate reductase1.5.1.30.462
3s7a684Dihydrofolate reductase1.5.1.30.462
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.462
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.462
4ead0NPThymidine phosphorylase2.4.2.40.462
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.462
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.462
4x5jFOLDihydrofolate reductase1.5.1.30.462
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.461
1hb3SCVIsopenicillin N synthase1.21.3.10.461
1nzq162Prothrombin3.4.21.50.461
2j5xGSPADP-ribosylation factor 6/0.461
2jh6894Prothrombin3.4.21.50.461
3vt8YI3Vitamin D3 receptor/0.461
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.461
4qenSAHHistone-lysine N-methyltransferase, H3 lysine-9 specific SUVH42.1.1.430.461
4riyADPEpidermal growth factor receptor2.7.10.10.461
4zvmDM2Ribosyldihydronicotinamide dehydrogenase [quinone]/0.461
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.460
1rbmKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.460
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.460
2xszATPRuvB-like 23.6.4.120.460
2z2w770Wee1-like protein kinase2.7.10.20.460
3ha5SFGHydroxymycolate synthase MmaA42.1.10.460
3in6FMNUncharacterized protein/0.460
3n8wFLPProstaglandin G/H synthase 11.14.99.10.460
3q3cNADNAD-dependent L-serine dehydrogenase/0.460
4b3aTACTetracycline repressor protein class D/0.460
4b8zNAPGDP-L-fucose synthase1.1.1.2710.460
4gxs0YSGlutamate receptor 2/0.460
4pnmNU1Tankyrase-22.4.2.300.460
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
1qiqACCIsopenicillin N synthase1.21.3.10.459
2c12FADNitroalkane oxidase1.7.3.10.459
2xhd7T9Glutamate receptor 2/0.459
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.459
3oqkS52Renin3.4.23.150.459
3otwCOAPhosphopantetheine adenylyltransferase/0.459
3qlrNDPDihydrofolate reductase1.5.1.30.459
3qwc98PProthrombin3.4.21.50.459
3vfqAR6Poly [ADP-ribose] polymerase 142.4.2.300.459
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.459
4fi1ATPCasein kinase II subunit alpha2.7.11.10.459
4kcfAKMFAD-dependent oxidoreductase/0.459
4tyj0LIFibroblast growth factor receptor 42.7.10.10.459
1e1mNAPNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.458
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.458
1q3gUDAUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.458
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.458
1yplRA8Prothrombin3.4.21.50.458
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.458
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
2jfhLK1UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.458
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.458
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.458
2xlrFADPutative flavin-containing monooxygenase/0.458
2y05NAPProstaglandin reductase 1/0.458
3bw4FMNPutative 2-nitropropane dioxygenase/0.458
3dhoB2MStreptogramin A acetyltransferase2.3.10.458
3gwfFADCyclohexanone monooxygenase/0.458
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.458
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.458
4fv7E94Mitogen-activated protein kinase 12.7.11.240.458
4rekFADCholesterol oxidase1.1.3.60.458
4ww4ADPRuvB-like helicase/0.458
1hk1T44Serum albumin/0.457
1p0hACOMycothiol acetyltransferase2.3.1.1890.457
1uzwCDHIsopenicillin N synthase1.21.3.10.457
2c2aADPSensor histidine kinase/0.457
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.457
3ac1KZITyrosine-protein kinase Lck2.7.10.20.457
3fknFKNMitogen-activated protein kinase 14/0.457
3hu3AGSTransitional endoplasmic reticulum ATPase3.6.4.60.457
3i6rJ5ZDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.457
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
3qdlFMNOxygen-insensitive NADPH nitroreductase/0.457
3sf6FDAGlutaryl-CoA dehydrogenase/0.457
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.457
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.457
4deg0JJHepatocyte growth factor receptor2.7.10.10.457
4hsuFADLysine-specific histone demethylase 1B10.457
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.457
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.457
4mxeACON-acetyltransferase ESCO12.3.10.457
4nteFADDepH/0.457
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.457
3uzaT4GAdenosine receptor A2a/0.457
1bq1CB3Thymidylate synthase/0.456
1d3pBT3Prothrombin3.4.21.50.456
1d4pBPPProthrombin3.4.21.50.456
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1n4vFADCholesterol oxidase1.1.3.60.456
1xzqFONtRNA modification GTPase MnmE3.6.50.456
2c42TPPPyruvate synthase/0.456
2jibADPOxalyl-CoA decarboxylase4.1.1.80.456
2tctCTCTetracycline repressor protein class D/0.456
3b3fSAHHistone-arginine methyltransferase CARM1/0.456
3br3ETHTH-type transcriptional regulator QacR/0.456
3uleC69Actin-related protein 3/0.456
3w0nANPHygromycin-B 4-O-kinase2.7.1.1630.456
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.456
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.456
4if5ACOAlpha-tubulin N-acetyltransferase 1/0.456
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.456
4rh10TTSpore photoproduct lyase/0.456
4xivADPChemotaxis protein CheA2.7.13.30.456
5a3bAPRSIR2 family protein/0.456
4uhrNGIAdenosine receptor A2a/0.456
1k22MELProthrombin3.4.21.50.455
1om1IQACasein kinase II subunit alpha2.7.11.10.455
1qvnFRIInterleukin-2/0.455
1uydPU8Heat shock protein HSP 90-alpha/0.455
1v79FR7Adenosine deaminase3.5.4.40.455
2bu9HFVIsopenicillin N synthase1.21.3.10.455
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.455
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.455
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.455
2g0gSP0Peroxisome proliferator-activated receptor gamma/0.455
2rl2UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.455
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.455
2xveFADPutative flavin-containing monooxygenase/0.455
2y6fM9FIsopenicillin N synthase1.21.3.10.455
3ha3SAHHydroxymycolate synthase MmaA42.1.10.455
3nhkVAPRibosyldihydronicotinamide dehydrogenase [quinone]/0.455
3qm4PN0Cytochrome P450 2D6/0.455
3qpvADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.455
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.455
4gk4L90Ephrin type-A receptor 32.7.10.10.455
4jufTPPBenzoylformate decarboxylase4.1.1.70.455
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.455
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.455
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.455
1i6xCMPcAMP-activated global transcriptional regulator CRP/0.454
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.454
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.454
2pvhP19Casein kinase II subunit alpha2.7.11.10.454
2vnkFADNADPH:ferredoxin reductase/0.454
2w98P1ZProstaglandin reductase 21.3.1.480.454
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.454
2zfq45UProthrombin3.4.21.50.454
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.454
3otqMZLBifunctional epoxide hydrolase 23.3.2.100.454
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.454
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.454
4dfrMTXDihydrofolate reductase1.5.1.30.454
4fdnFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.454
5cdtPFBAlcohol dehydrogenase E chain1.1.1.10.454
1b8sFADCholesterol oxidase1.1.3.60.453
1diuBDMDihydrofolate reductase1.5.1.30.453
1fmlRTLRetinol dehydratase/0.453
1lf3EH5Plasmepsin-23.4.23.390.453
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.453
1zgaHMKIsoflavone 4'-O-methyltransferase/0.453
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.453
2ihuTP9N(2)-(2-carboxyethyl)arginine synthase/0.453
2xikJ60Serine/threonine-protein kinase 252.7.11.10.453
2zbaZBATrichothecene 3-O-acetyltransferase/0.453
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3bl7DD1m7GpppX diphosphatase3.6.1.590.453
3bzuA21Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3fkoFKOMitogen-activated protein kinase 14/0.453
3kpzZNEVitamin D3 receptor/0.453
3mjeNDPAmphB/0.453
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.453
4b7sQLECytochrome P450 monooxygenase PikC/0.453
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.453
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.453
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.453
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.453
1g4tFTPThiamine-phosphate synthase/0.452
1hb1OCVIsopenicillin N synthase1.21.3.10.452
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.452
1jpaANPEphrin type-B receptor 22.7.10.10.452
1jujLYAThymidylate synthase2.1.1.450.452
1k6tXN1Gag-Pol polyprotein3.4.23.160.452
1mabADPATP synthase subunit beta, mitochondrial3.6.3.140.452
1ry8RUTAldo-keto reductase family 1 member C3/0.452
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.452
1z1fSTLResveratrol synthase/0.452
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.452
2w6oOA3Biotin carboxylase6.3.4.140.452
2z3uCRRCytochrome P450/0.452
3a1l2CCCytochrome P450/0.452
3bloQEIQueuine tRNA-ribosyltransferase2.4.2.290.452
3cgoJNOMitogen-activated protein kinase 102.7.11.240.452
3fznD7KBenzoylformate decarboxylase4.1.1.70.452
3hx4ANPCalmodulin-domain protein kinase 1/0.452
3uyt0CKCasein kinase I isoform delta2.7.11.10.452
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.452
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.452
4jq8KJ8Epidermal growth factor receptor2.7.10.10.452
4l4xNDPAmphI/0.452
1e7aPFLSerum albumin/0.451
1kziTHGThymidylate synthase/0.451
1lpfFADDihydrolipoyl dehydrogenase1.8.1.40.451
1mvsDTMDihydrofolate reductase1.5.1.30.451
1ppjANYCytochrome b/0.451
2b1pAIZMitogen-activated protein kinase 102.7.11.240.451
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.451
2dr3ADPUPF0273 protein PH0284/0.451
2hbhXE4Vitamin D3 receptor A/0.451
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.451
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.451
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.451
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.451
2qimZEAClass 10 plant pathogenesis-related protein/0.451
2tscCB3Thymidylate synthase/0.451
2uxpCLMHTH-type transcriptional regulator TtgR/0.451
2z4zSC0Geranylgeranyl pyrophosphate synthase/0.451
2zi224UProthrombin3.4.21.50.451
3d7zGK5Mitogen-activated protein kinase 14/0.451
3f63GTXGlutathione transferase GST1-4/0.451
3fl4FL4Mitogen-activated protein kinase 14/0.451
3mb714ICasein kinase II subunit alpha2.7.11.10.451
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.451
3ska053Genome polyprotein2.7.7.480.451
3vo30KFVascular endothelial growth factor receptor 22.7.10.10.451
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.451
4eu5COASuccinyl-CoA:acetate CoA-transferase/0.451
4kb81QOCasein kinase I isoform delta2.7.11.10.451
4o0sADNAurora kinase A2.7.11.10.451
4o2bLOCTubulin beta-2B chain/0.451
4uxq0LIFibroblast growth factor receptor 42.7.10.10.451
1bxoPP7Penicillopepsin-13.4.23.200.450
1dajMOTDihydrofolate reductase1.5.1.30.450
1gqtACPRibokinase/0.450
1jd0AZMCarbonic anhydrase 124.2.1.10.450
1krhFADBenzoate 1,2-dioxygenase electron transfer component1.18.1.30.450
2ag0TPPBenzaldehyde lyase/0.450
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.450
2hcdBIVVitamin D3 receptor A/0.450
2ignFADPyranose 2-oxidase/0.450
2w71L23Biotin carboxylase6.3.4.140.450
2zc922UProthrombin3.4.21.50.450
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.450
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
3vtdTKDVitamin D3 receptor/0.450
3w5uFADFerredoxin/0.450
3zm5IGMUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.450
3zuxTCHTransporter/0.450
4bkjSTIEpithelial discoidin domain-containing receptor 12.7.10.10.450
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.450
4ia7BIVVitamin D3 receptor A/0.450
4jk3NADUncharacterized protein/0.450
4xgiNADGlutamate dehydrogenase/0.450
5dp2NAPCurF/0.450
3pwhZMAAdenosine receptor A2a/0.450
1dfoFFOSerine hydroxymethyltransferase2.1.2.10.449
1m17AQ4Epidermal growth factor receptor2.7.10.10.449
1sejF89Bifunctional dihydrofolate reductase-thymidylate synthase/0.449
1ta6177Prothrombin3.4.21.50.449
1w06W05Isopenicillin N synthase1.21.3.10.449
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.449
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.449
2wo7ASVIsopenicillin N synthase1.21.3.10.449
2xvu9DNSerum albumin/0.449
3gyiFADCholesterol oxidase1.1.3.60.449
3ibdCPZCytochrome P450 2B61.14.130.449
3mvm39PMitogen-activated protein kinase 14/0.449
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.449
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.449
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.449
3v9y24LPeroxisome proliferator-activated receptor gamma/0.449
3vt5YI2Vitamin D3 receptor/0.449
3zkyWT4Isopenicillin N synthase1.21.3.10.449
4bb3KKAIsopenicillin N synthase1.21.3.10.449
4dymIYZActivin receptor type-12.7.11.300.449
4fj1GEN17beta-hydroxysteroid dehydrogenase/0.449
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.449
5dr2ATPAurora kinase A2.7.11.10.449
1dnaCB3Thymidylate synthase/0.448
1gqyACPUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.448
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1lf2R37Plasmepsin-23.4.23.390.448
1mczRMNBenzoylformate decarboxylase4.1.1.70.448
1pjkANPCasein kinase II subunit alpha2.7.11.10.448
1uyfPU1Heat shock protein HSP 90-alpha/0.448
1zprCB3Thymidylate synthase/0.448
1zzlTZYMitogen-activated protein kinase 14/0.448
2g247IGRenin3.4.23.150.448
2in6839Wee1-like protein kinase2.7.10.20.448
2pdaTPPPyruvate synthase/0.448
2po7CHDFerrochelatase, mitochondrial4.99.1.10.448
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.448
2x6o2TCTetracycline repressor protein class D/0.448
2y30SM8Putative repressor SimReg2/0.448
2y6o1N1Ephrin type-A receptor 42.7.10.10.448
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.448
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3e92G6AMitogen-activated protein kinase 14/0.448
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.448
3kytHC2Nuclear receptor ROR-gamma/0.448
3pe6ZYHMonoglyceride lipase/0.448
3pqbVGPPutative oxidoreductase/0.448
3r3d4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.448
3zc3NAPFerredoxin--NADP reductase1.18.1.20.448
4b7dQLECytochrome P450 monooxygenase PikC/0.448
4dh60KNBeta-secretase 13.4.23.460.448
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.448
4jazSTLPeroxisome proliferator-activated receptor gamma/0.448
4kqqVPPPeptidoglycan D,D-transpeptidase FtsI/0.448
4qnaX11Serine/threonine-protein kinase 242.7.11.10.448
4ruoBIVVitamin D3 receptor A/0.448
5cmx0G6Prothrombin3.4.21.50.448
5kjePFBAlcohol dehydrogenase E chain1.1.1.10.448
3sn6P0GBeta-2 adrenergic receptor/0.448
1a80NDP2,5-diketo-D-gluconic acid reductase A1.1.1.3460.447
1n4hREANuclear receptor ROR-beta/0.447
1n4uFAECholesterol oxidase1.1.3.60.447
2bxaC1FSerum albumin/0.447
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.447
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.447
2uuk897Prothrombin3.4.21.50.447
2vzmNRBCytochrome P450 monooxygenase PikC/0.447
3biu10UProthrombin3.4.21.50.447
3drcMTXDihydrofolate reductase1.5.1.30.447
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3ic9FADPutative dihydrolipoamide dehydrogenase/0.447
3k2hLYABifunctional dihydrofolate reductase-thymidylate synthase/0.447
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.447
3upi0C2Genome polyprotein2.7.7.480.447
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.447
4ia3BIVVitamin D3 receptor A/0.447
4j7xSASSepiapterin reductase1.1.1.1530.447
4jtrIZPAldo-keto reductase family 1 member C2/0.447
4mr61K0Bromodomain-containing protein 2/0.447
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.447
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.447
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.447
5cdgPFBAlcohol dehydrogenase E chain1.1.1.10.447
1c4yIH3Prothrombin3.4.21.50.446
1eioGCHGastrotropin/0.446
1lcoPPYCytochrome b2, mitochondrial1.1.2.30.446
1r2jFADFkbI/0.446
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2fhnBNIAvidin-related protein 4/5/0.446
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.446
2pvlP55Casein kinase II subunit alpha2.7.11.10.446
2r43G3GGag-Pol polyprotein3.4.23.160.446
2vbpVB1Isopenicillin N synthase1.21.3.10.446
2werRDCATP-dependent molecular chaperone HSP82/0.446
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.446
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.446
2ylxFADPhenylacetone monooxygenase1.14.13.920.446
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
3g0fB49Mast/stem cell growth factor receptor Kit2.7.10.10.446
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.446
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.446
3vquO22Dual specificity protein kinase TTK2.7.12.10.446
3vwdACOAlpha-tubulin N-acetyltransferase 1/0.446
3w0c6DSVitamin D3 receptor/0.446
3zze6XPHepatocyte growth factor receptor2.7.10.10.446
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4brxKGWFocal adhesion kinase 12.7.10.20.446
4elf35IDihydrofolate reductase/0.446
4jjiNADAlcohol dehydrogenase class-3/0.446
4l9q9TPSerum albumin/0.446
4qmpDKISerine/threonine-protein kinase 242.7.11.10.446
4yryFADGlutamate synthase, beta subunit/0.446
5itzLOCTubulin beta-2B chain/0.446
1cboFADCholesterol oxidase1.1.3.60.445
1hdrNADDihydropteridine reductase1.5.1.340.445
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.445
1mxtFAECholesterol oxidase1.1.3.60.445
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.445
1pw6FRBInterleukin-2/0.445
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.445
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.445
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.445
1uymPU3Heat shock protein HSP 90-beta/0.445
1vrwNAIEnoyl-ACP reductase/0.445
2ek4SAHDiphthine synthase/0.445
2gvcFADThiol-specific monooxygenase1.14.130.445
2q4wFADCytokinin dehydrogenase 71.5.99.120.445
2tpsTPSThiamine-phosphate synthase/0.445
2v3wTPPBenzoylformate decarboxylase4.1.1.70.445
2v52LABActin, alpha skeletal muscle/0.445
2ykjYKJHeat shock protein HSP 90-alpha/0.445
2yoj8Y6Genome polyprotein2.7.7.480.445
2zhf49UProthrombin3.4.21.50.445
3bac3B9DNA ligase/0.445
3bbrBHYGlutamate receptor 2/0.445
3fl8RARDihydrofolate reductase/0.445
3ljtLA3A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.445
3oibFDAPutative acyl-CoA dehydrogenase/0.445
3pm1ETHTH-type transcriptional regulator QacR/0.445
3stv3HOMethylketone synthase I/0.445
3stw2TDMethylketone synthase I/0.445
3v3vMYUMitogen-activated protein kinase 82.7.11.240.445
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.445
3zkuHCVIsopenicillin N synthase1.21.3.10.445
4ap7F47Hepatocyte growth factor receptor2.7.10.10.445
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.445
4c3rACPAurora kinase A2.7.11.10.445
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.445
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.445
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.445
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.445
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.445
4ia1BIVVitamin D3 receptor A/0.445
4jbqVX6Aurora kinase A2.7.11.10.445
4jr7GNPCasein kinase II subunit alpha2.7.11.10.445
4rujVDXVitamin D3 receptor A/0.445
4xgxADPFAD:protein FMN transferase/0.445
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.445
5drdATPAurora kinase A2.7.11.10.445
5kgpACOPredicted acetyltransferase/0.445
3qakUKAAdenosine receptor A2a/0.445
1bwkFMNNADPH dehydrogenase 11.6.99.10.444
1dyjDDFDihydrofolate reductase1.5.1.30.444
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.444
1uy8PU5Heat shock protein HSP 90-alpha/0.444
1vj3TABDihydrofolate reductase1.5.1.30.444
1zgi382Prothrombin3.4.21.50.444
2bbqPFGThymidylate synthase/0.444
2excJNKMitogen-activated protein kinase 102.7.11.240.444
2i9pNAD3-hydroxyisobutyrate dehydrogenase, mitochondrial1.1.1.310.444
2jb4A14Isopenicillin N synthase1.21.3.10.444
2v59LZKBiotin carboxylase6.3.4.140.444
2yee2ECHeat shock protein HSP 90-alpha/0.444
3fl9TOPDihydrofolate reductase/0.444
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.444
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3mdvCL6Cholesterol 24-hydroxylase/0.444
3p6pA6BCamphor 5-monooxygenase1.14.15.10.444
3qh23NMThiazole tautomerase/0.444
3rbqGLY_ALA_GLY_ALA_DAOProtein unc-119 homolog A/0.444
3uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.444
3wagTYDGlycosyltransferase/0.444
3wfjNAD2-dehydropantoate 2-reductase/0.444
4ax9N5NProthrombin3.4.21.50.444
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.444
4dhyS41Glucokinase2.7.1.20.444
4eb4D16Thymidylate synthase2.1.1.450.444
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.444
4g20484Vitamin D3 receptor A/0.444
4h1e10JBeta-secretase 13.4.23.460.444
4ib4ERM5-hydroxytryptamine receptor 2B/0.444
4jlj1NMDeoxycytidine kinase2.7.1.740.444
4ko8AGSTransitional endoplasmic reticulum ATPase3.6.4.60.444
4kvmSER_ALA_SER_GLU_1XEN-terminal acetyltransferase A complex catalytic subunit ard12.3.1.880.444
4l9kEHFSerum albumin/0.444
4ltsLTSNicotinamide phosphoribosyltransferase2.4.2.120.444
4nieNBHNuclear receptor ROR-gamma/0.444
4wjiNAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase/0.444
4yntFDAGlucose oxidase, putative/0.444
5cdsPFBAlcohol dehydrogenase E chain1.1.1.10.444
5hsaFASAlcohol oxidase 11.1.3.130.444
5kghACOPredicted acetyltransferase/0.444
4xnw2IDP2Y purinoceptor 1/0.444
1bk0ACVIsopenicillin N synthase1.21.3.10.443
1h73ANPHomoserine kinase2.7.1.390.443
1jioDEB6-deoxyerythronolide B hydroxylase/0.443
1jtuLYBThymidylate synthase/0.443
1knrFADL-aspartate oxidase1.4.3.160.443
1mawATPTryptophan--tRNA ligase6.1.1.20.443
1mczTDPBenzoylformate decarboxylase4.1.1.70.443
1pdhFASp-hydroxybenzoate hydroxylase/0.443
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1t4u81AProthrombin3.4.21.50.443
1t4v14AProthrombin3.4.21.50.443
2ejvNADL-threonine 3-dehydrogenase/0.443
2hq9FADMll6688 protein/0.443
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.443
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.443
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.443
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.443
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.443
2x9dITCTetracycline repressor protein class D/0.443
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.443
2y3rTRKTamL/0.443
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.443
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.443
2zevB71Geranylgeranyl pyrophosphate synthase/0.443
3bgrT27Gag-Pol polyprotein2.7.7.490.443
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.443
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.443
3icrCOACoenzyme A disulfide reductase/0.443
3nhfVVVRibosyldihydronicotinamide dehydrogenase [quinone]/0.443
3ol5SAWCamphor 5-monooxygenase1.14.15.10.443
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.443
3v4tUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.443
3vt9YI4Vitamin D3 receptor/0.443
3wowANPCasein kinase II subunit alpha2.7.11.10.443
4a802ANMajor pollen allergen Bet v 1-A/0.443
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.443
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.443
4g6hFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.443
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.443
4gy2LARActin, alpha skeletal muscle/0.443
4jlk1NODeoxycytidine kinase2.7.1.740.443
4jr3KJREpidermal growth factor receptor2.7.10.10.443
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.443
4nxuADPMitochondrial dynamics protein MID51/0.443
4plpNADHomospermidine synthase2.5.1.440.443
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.443
4tleAGSCircadian clock protein kinase KaiC2.7.11.10.443
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
5bn3ADPV-type ATP synthase alpha chain/0.443
5bn3ADPNEQ263/0.443
5ctsCMCCitrate synthase, mitochondrial2.3.3.10.443
5f5rANPHeat shock protein 75 kDa, mitochondrial/0.443
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.442
1knpFADL-aspartate oxidase1.4.3.160.442
1pkfEPDEpothilone C/D epoxidase1.140.442
1t0iFMNNAD(P)H-dependent FMN reductase LOT6/0.442
1thnADPAnti-sigma F factor/0.442
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.442
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.442
1ypmRA4Prothrombin3.4.21.50.442
1z4uPH9Polyprotein/0.442
1zg32HIIsoflavone 4'-O-methyltransferase/0.442
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.442
2d29FADAcyl-CoA dehydrogenase/0.442
2harOCCVitamin D3 receptor/0.442
2hasC3OVitamin D3 receptor/0.442
2hkoFADLysine-specific histone demethylase 1A10.442
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.442
2w03ADNAcsD/0.442
2xx91NFGlutamate receptor 2/0.442
3ad9FADSubunit beta of sarcosine oxidase/0.442
3dlgGWEGag-Pol polyprotein2.7.7.490.442
3e6oA55Nitric oxide synthase, inducible1.14.13.390.442
3h6vNS6Glutamate receptor 2/0.442
3iaeD7KBenzaldehyde lyase/0.442
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3mteSAM16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.442
3qfcFADNADPH--cytochrome P450 reductase/0.442
3ruvANPChaperonin/0.442
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.442
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.442
4af3VX6Aurora kinase B2.7.11.10.442
4az29MUProthrombin3.4.21.50.442
4bwxAGSPAB-dependent poly(A)-specific ribonuclease subunit pan3/0.442
4c02TAKActivin receptor type-12.7.11.300.442
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.442
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.442
4h6pFMNChromate reductase/0.442
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.442
4itfTFYVitamin D3 receptor/0.442
4ixc1JDGlucokinase2.7.1.20.442
4j7uYTZSepiapterin reductase1.1.1.1530.442
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.442
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.442
4pkl1GHUncharacterized protein/0.442
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
5fm7ADPRuvB-like helicase/0.442
5kj6PFBAlcohol dehydrogenase E chain1.1.1.10.442
1c0lFADD-amino-acid oxidase1.4.3.30.441
1c6yMK1Protease/0.441
1drbMTXDihydrofolate reductase1.5.1.30.441
1ia4TQ6Dihydrofolate reductase1.5.1.30.441
1qjfACSIsopenicillin N synthase1.21.3.10.441
1z71L17Prothrombin3.4.21.50.441
2dhfDZFDihydrofolate reductase1.5.1.30.441
2fpcSCGStrictosidine synthase4.3.3.20.441
2hb8MVDVitamin D3 receptor/0.441
2iyaZIOOleandomycin glycosyltransferase/0.441
2jkkBI9Focal adhesion kinase 12.7.10.20.441
2om9AJAPeroxisome proliferator-activated receptor gamma/0.441
2pmoHMDProtein kinase 7/0.441
2pwcG3GGag-Pol polyprotein3.4.23.160.441
2qnqQN3Gag-Pol polyprotein3.4.23.160.441
2v16C47Renin3.4.23.150.441
2vq7FADPutative flavin-containing monooxygenase/0.441
2y37A54Nitric oxide synthase, inducible1.14.13.390.441
2zda32UProthrombin3.4.21.50.441
2zjwREFCasein kinase II subunit alpha2.7.11.10.441
2zwaSAHtRNA wybutosine-synthesizing protein 42.1.1.2900.441
3d8bADPFidgetin-like protein 13.6.40.441
3e6yCW114-3-3-like protein C/0.441
3fraI2HDihydrofolate reductase1.5.1.30.441
3gw9VNILanosterol 14-alpha-demethylase/0.441
3kgcLY7Glutamate receptor 2/0.441
3litE15Protease/0.441
3n10CMPAdenylate cyclase 2/0.441
3nwq2NCGag-Pol polyprotein3.4.23.160.441
3p4tFAOPutative acyl-CoA dehydrogenase/0.441
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.441
3t14FADSulfide-quinone reductase/0.441
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.441
4a6eASEAcetylserotonin O-methyltransferase2.1.1.40.441
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.441
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4ce2BO5ATP-dependent molecular chaperone HSP82/0.441
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.441
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.441
4h9506UDihydrofolate reductase1.5.1.30.441
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
4ixgIXGDihydrofolate reductase1.5.1.30.441
4la0198Serum albumin/0.441
4mlp2CXCryptochrome-2/0.441
4nb6444Nuclear receptor ROR-gamma/0.441
4udqFAD5-(hydroxymethyl)furfural oxidase/0.441
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.441
5a3cNADSIR2 family protein/0.441
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.441
4mqt2CUMuscarinic acetylcholine receptor M2/0.441
1dhjMTXDihydrofolate reductase1.5.1.30.440
1j7uANPAminoglycoside 3'-phosphotransferase2.7.1.950.440
1jqiFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.440
1mueCDDProthrombin3.4.21.50.440
1rfuADPPyridoxal kinase2.7.1.350.440
1rkhVD2Vitamin D3 receptor/0.440
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.440
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.440
1swdBTNStreptavidin/0.440
1umlFR4Adenosine deaminase3.5.4.40.440
1uykPUXHeat shock protein HSP 90-alpha/0.440
1ypkCCRProthrombin3.4.21.50.440
2acwUPGGlycosyltransferase/0.440
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.440
2fzwNADAlcohol dehydrogenase class-31.1.1.10.440
2gjnFMNNitronate monooxygenase1.13.12.160.440
2hpsCTZCa2+-triggered coelenterazine-binding protein 1/0.440
2itwITQEpidermal growth factor receptor2.7.10.10.440
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.440
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.440
2oz6CMPCyclic AMP receptor-like protein/0.440
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
2vqoTFGHistone deacetylase 43.5.1.980.440
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.440
2wouZZFTGF-beta receptor type-12.7.11.300.440
2wsiFADFAD synthase2.7.7.20.440
2x7hPFNProstaglandin reductase 310.440
2y0mACOHistone acetyltransferase KAT8/0.440
2zb45OPProstaglandin reductase 21.3.1.480.440
3cqwCQWRAC-alpha serine/threonine-protein kinase2.7.11.10.440
3crlANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.440
3hatGLY_VAL_ARG_RNGProthrombin3.4.21.50.440
3hmm855TGF-beta receptor type-12.7.11.300.440
3imgBZ2Pantothenate synthetase6.3.2.10.440
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3m7rVDXVitamin D3 receptor/0.440
3nhjA2ZRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
3qp0NI8Gag-Pol polyprotein3.4.23.160.440
3qv2SAH5-cytosine DNA methyltransferase/0.440
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
4buxF35Tankyrase-22.4.2.300.440
4c1fX8ZMetallo-beta-lactamase type 2/0.440
4ez50RSCyclin-dependent kinase 62.7.11.220.440
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
4gevCB3Thymidylate synthase/0.440
4gg70J8Hepatocyte growth factor receptor2.7.10.10.440
4gk3L87Ephrin type-A receptor 32.7.10.10.440
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.440
4o78SAVBromodomain-containing protein 4/0.440
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.440
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.440
4zasTYDCalS13/0.440