sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Glutamate receptor 2
ID:	GRIA2_RAT
AC:	P19491
Organism:	Rattus norvegicus
Reign:	Eukaryota
TaxID:	10116
EC Number:	/

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Chains:

Chain Name:	Percentage of Residues within binding site
A	54 %
B	46 %

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Ligand binding site composition:

B-Factor:	11.932
Number of residues:	37
Including
Standard Amino Acids:	37
Non Standard Amino Acids:	0
Water Molecules:	0
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
1.099	1596.375

% Hydrophobic	% Polar
47.15	52.85
According to VolSite

HET Code:	LY7
Formula:	C19H22N2O2S
Molecular weight:	342.455 g/mol
DrugBank ID:	-
Buried Surface Area:	71.28 %
Polar Surface area:	78.34 Å2

Number of
H-Bond Acceptors:	3
H-Bond Donors:	1
Rings:	2
Aromatic rings:	2
Anionic atoms:	0
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	6

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Mass center Coordinates

X	Y	Z
16.0766	47.2499	-2.27283

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