1.550 Å
X-ray
2009-10-28
Name: | Glutamate receptor 2 |
---|---|
ID: | GRIA2_RAT |
AC: | P19491 |
Organism: | Rattus norvegicus |
Reign: | Eukaryota |
TaxID: | 10116 |
EC Number: | / |
Chain Name: | Percentage of Residues within binding site |
---|---|
A | 54 % |
B | 46 % |
B-Factor: | 11.932 |
---|---|
Number of residues: | 37 |
Including | |
Standard Amino Acids: | 37 |
Non Standard Amino Acids: | 0 |
Water Molecules: | 0 |
Cofactors: | |
Metals: |
Ligandability | Volume (Å3) |
---|---|
1.099 | 1596.375 |
% Hydrophobic | % Polar |
---|---|
47.15 | 52.85 |
According to VolSite |
HET Code: | LY7 |
---|---|
Formula: | C19H22N2O2S |
Molecular weight: | 342.455 g/mol |
DrugBank ID: | - |
Buried Surface Area: | 71.28 % |
Polar Surface area: | 78.34 Å2 |
Number of | |
---|---|
H-Bond Acceptors: | 3 |
H-Bond Donors: | 1 |
Rings: | 2 |
Aromatic rings: | 2 |
Anionic atoms: | 0 |
Cationic atoms: | 0 |
Rule of Five Violation: | 0 |
Rotatable Bonds: | 6 |
X | Y | Z |
---|---|---|
16.0766 | 47.2499 | -2.27283 |
Represent the protein/ligand binding mode, centered on the ligand
Dashed lines represents hydrogen bonds and metal interactions
Green residue labels for amino acids with hydrophobic contacts (green lines) to the ligand
Ligand | Protein | Interaction | |||
---|---|---|---|---|---|
Atom | Atom | Residue | Distance (Å) | Angle (°) | Type |
CAB | CG2 | ILE- 92 | 3.93 | 0 | Hydrophobic |
CAA | CB | LYS- 104 | 4.08 | 0 | Hydrophobic |
CAJ | CG | PRO- 105 | 4.16 | 0 | Hydrophobic |
CAL | CG | PRO- 105 | 3.91 | 0 | Hydrophobic |
CAK | CB | PRO- 105 | 3.95 | 0 | Hydrophobic |
CAM | CG | PRO- 105 | 3.47 | 0 | Hydrophobic |
NAQ | O | PRO- 105 | 2.8 | 149.75 | H-Bond (Ligand Donor) |
CAK | CB | SER- 108 | 4.15 | 0 | Hydrophobic |
CAO | CB | SER- 108 | 3.76 | 0 | Hydrophobic |
CAC | CB | SER- 217 | 4.34 | 0 | Hydrophobic |
CAR | CB | SER- 217 | 3.97 | 0 | Hydrophobic |
CAB | CB | LYS- 218 | 4.29 | 0 | Hydrophobic |
CAA | CG1 | VAL- 238 | 4.21 | 0 | Hydrophobic |
CAB | CD2 | LEU- 239 | 3.66 | 0 | Hydrophobic |
NAD | OG | SER- 242 | 3.06 | 161.05 | H-Bond (Protein Donor) |
CAA | CB | SER- 242 | 3.67 | 0 | Hydrophobic |