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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3zc5W9ZHepatocyte growth factor receptor2.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3zc5W9ZHepatocyte growth factor receptor2.7.10.11.000
3zxzKRWHepatocyte growth factor receptor2.7.10.10.765
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.709
4gg70J8Hepatocyte growth factor receptor2.7.10.10.631
2wgjVGHHepatocyte growth factor receptor2.7.10.10.617
4gg50J3Hepatocyte growth factor receptor2.7.10.10.601
4deg0JJHepatocyte growth factor receptor2.7.10.10.597
4ap7F47Hepatocyte growth factor receptor2.7.10.10.577
3zze6XPHepatocyte growth factor receptor2.7.10.10.566
3zbx6XEHepatocyte growth factor receptor2.7.10.10.554
3a4pDFQHepatocyte growth factor receptor2.7.10.10.551
2wkmPFYHepatocyte growth factor receptor2.7.10.10.540
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.537
2qo9ANPEphrin type-A receptor 32.7.10.10.526
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.518
4kb81QOCasein kinase I isoform delta2.7.11.10.512
4iwd1JCHepatocyte growth factor receptor2.7.10.10.511
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.508
4loqSB4Mitogen-activated protein kinase 14/0.506
2wxvWXVCyclin-dependent kinase 22.7.11.220.505
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.505
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.502
4dymIYZActivin receptor type-12.7.11.300.502
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.500
4alhA9PBromodomain-containing protein 2/0.499
4qmpDKISerine/threonine-protein kinase 242.7.11.10.498
1kl2FONSerine hydroxymethyltransferase/0.497
2xikJ60Serine/threonine-protein kinase 252.7.11.10.497
4gmy0X5Tyrosine-protein kinase JAK2/0.497
1jpaANPEphrin type-B receptor 22.7.10.10.494
1oiyN41Cyclin-dependent kinase 22.7.11.220.494
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.494
1x8lOXRRetinol dehydratase/0.493
3oqkS52Renin3.4.23.150.493
3qaiXNNKetohexokinase/0.493
4kip1R9Mitogen-activated protein kinase 14/0.493
4qmzB49Serine/threonine-protein kinase 242.7.11.10.493
3c1xCKKHepatocyte growth factor receptor2.7.10.10.492
3frqERYErythromycin resistance repressor protein/0.492
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.492
5e8wSTUTGF-beta receptor type-12.7.11.300.492
3fln3FNMitogen-activated protein kinase 14/0.491
4c02TAKActivin receptor type-12.7.11.300.491
4lopSB4Mitogen-activated protein kinase 14/0.491
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.490
1oi9N20Cyclin-dependent kinase 22.7.11.220.489
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.489
4u0mGTPCyclic GMP-AMP synthase/0.489
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.488
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.487
1ouk084Mitogen-activated protein kinase 14/0.486
3dogNNNCyclin-dependent kinase 22.7.11.220.486
5fd8A5APutative carboxypeptidase yocD/0.485
3bhtMFRCyclin-dependent kinase 22.7.11.220.484
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.484
2gjlFMNNitronate monooxygenase1.13.12.160.483
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.483
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.483
1rfvADPPyridoxal kinase2.7.1.350.482
2ghlLIBMitogen-activated protein kinase 14/0.482
2uzlC94Cyclin-dependent kinase 22.7.11.220.482
3flwFLWMitogen-activated protein kinase 14/0.482
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.482
4fod0UVALK tyrosine kinase receptor2.7.10.10.482
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.482
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.482
5eypLOCTubulin beta chain/0.482
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.481
2x1nX1NCyclin-dependent kinase 22.7.11.220.481
4o4fATPKinase/0.481
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.481
1vjy460TGF-beta receptor type-12.7.11.300.480
3hx4ANPCalmodulin-domain protein kinase 1/0.480
3ibqATPPyridoxal kinase/0.480
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.480
4ryvZEAProtein LlR18A/0.480
4uyf73BBromodomain-containing protein 2/0.480
2ftoCB3Thymidylate synthase/0.479
2wpa889Cyclin-dependent kinase 22.7.11.220.479
3gxlQIGTGF-beta receptor type-12.7.11.300.479
3iw4LW4Protein kinase C alpha type2.7.11.130.479
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.478
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.478
2q7vFADThioredoxin reductase/0.478
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.478
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.478
3nww3NWMitogen-activated protein kinase 14/0.478
4bgg844Activin receptor type-12.7.11.300.478
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.477
3p3zP3ZPutative cytochrome P450/0.477
3tneRITCandidapepsin-13.4.23.240.477
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.477
4qmySTUSerine/threonine-protein kinase 242.7.11.10.477
1oc1ASVIsopenicillin N synthase1.21.3.10.476
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.476
3owj1ELCasein kinase II subunit alpha2.7.11.10.476
3pl8FADPyranose 2-oxidase/0.476
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.475
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.475
3sdkP3NProteasome subunit beta type-53.4.25.10.475
3sdkP3NProteasome subunit beta type-63.4.25.10.475
4fkr45KCyclin-dependent kinase 22.7.11.220.475
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.475
1fvv107Cyclin-dependent kinase 22.7.11.220.474
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.474
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.474
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.474
4jr7GNPCasein kinase II subunit alpha2.7.11.10.474
1csnATPCasein kinase I homolog 12.7.11.10.473
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.473
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.473
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.473
3c4zADPRhodopsin kinase/0.473
3zkyWT4Isopenicillin N synthase1.21.3.10.473
4jx1CAHCamphor 5-monooxygenase1.14.15.10.473
4uyg73BBromodomain-containing protein 2/0.473
1cqp803Integrin alpha-L/0.472
1pjkANPCasein kinase II subunit alpha2.7.11.10.472
2yeiXQIHeat shock protein HSP 90-alpha/0.472
3a7hATPSerine/threonine-protein kinase 242.7.11.10.472
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.472
3l0lHC3Nuclear receptor ROR-gamma/0.472
4aa4QC0Mitogen-activated protein kinase 14/0.472
4aqc88ATyrosine-protein kinase JAK2/0.472
4ewqMWLMitogen-activated protein kinase 14/0.472
4jia1K3Tyrosine-protein kinase JAK2/0.472
4qo9627Serine/threonine-protein kinase 242.7.11.10.472
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
1unlRRCCyclin-dependent-like kinase 52.7.11.10.471
2x7jTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.471
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.471
3flzFLZMitogen-activated protein kinase 14/0.471
3s1dZIRCytokinin dehydrogenase 11.5.99.120.471
3tnwF18Cyclin-dependent kinase 22.7.11.220.471
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.471
4g2fC07Ephrin type-A receptor 32.7.10.10.471
4ib4ERM5-hydroxytryptamine receptor 2B/0.471
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.470
2b7aIZATyrosine-protein kinase JAK2/0.470
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.470
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.470
2vmyFFOSerine hydroxymethyltransferase/0.470
3hk1B64Fatty acid-binding protein, adipocyte/0.470
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.470
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.470
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.470
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.470
4dpy2P0Mevalonate diphosphate decarboxylase/0.470
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.470
4wboANWRhodopsin kinase/0.470
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.470
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.469
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.469
2yboSAHMethyltransferase/0.469
3fhxPXLPyridoxal kinase2.7.1.350.469
3lctADPALK tyrosine kinase receptor2.7.10.10.469
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.469
3tm5SFGUncharacterized protein/0.469
4f650S9Fibroblast growth factor receptor 1/0.469
4foc0UUALK tyrosine kinase receptor2.7.10.10.469
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.469
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.469
1ai9NDPDihydrofolate reductase1.5.1.30.468
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.468
1rw8580TGF-beta receptor type-12.7.11.300.468
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.468
2eglSAHDiphthine synthase/0.468
2qo7ANPEphrin type-A receptor 32.7.10.10.468
2vcmM11Isopenicillin N synthase1.21.3.10.468
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.468
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.468
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.468
4b1fKRHGlutamate racemase/0.468
1aq1STUCyclin-dependent kinase 22.7.11.220.467
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.467
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.467
2gv8NDPThiol-specific monooxygenase1.14.130.467
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.467
3dt1P40Mitogen-activated protein kinase 14/0.467
1rfuADPPyridoxal kinase2.7.1.350.466
1t4u81AProthrombin3.4.21.50.466
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.466
3uyt0CKCasein kinase I isoform delta2.7.11.10.466
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.466
4e4m0NHTyrosine-protein kinase JAK2/0.466
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.466
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.466
2p5fSAHDiphthine synthase/0.465
2vd5BI8Myotonin-protein kinase2.7.11.10.465
3mtlFEFCyclin-dependent kinase 162.7.11.220.465
4frkDWDBeta-secretase 13.4.23.460.465
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.464
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.464
2acwUPGGlycosyltransferase/0.464
2bkzSBCCyclin-dependent kinase 22.7.11.220.464
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.464
2oyfIACBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.464
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.464
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.464
3fskRO6Mitogen-activated protein kinase 14/0.464
3zep1NXTyrosine-protein kinase JAK32.7.10.20.464
4a8v2ANMajor pollen allergen Bet v 1-J/0.464
4bis8HQLysine-specific demethylase 4A1.14.110.464
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.464
4yuqKS1Calmodulin-like domain protein kinase/0.464
1di8DTQCyclin-dependent kinase 22.7.11.220.463
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.463
2br5SAHCephalosporin hydroxylase CmcI/0.463
2ignFADPyranose 2-oxidase/0.463
2j0m4STFocal adhesion kinase 12.7.10.20.463
2vagV25Dual specificity protein kinase CLK12.7.12.10.463
2wihP48Cyclin-dependent kinase 22.7.11.220.463
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.463
3wbbNAPMeso-diaminopimelate D-dehydrogenase/0.463
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.463
4fnyI3KALK tyrosine kinase receptor2.7.10.10.463
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.463
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.463
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.463
1e9hINRCyclin-dependent kinase 22.7.11.220.462
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.462
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.462
1r2jFADFkbI/0.462
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
2ek4SAHDiphthine synthase/0.462
2imfTOM2-hydroxychromene-2-carboxylate isomerase5.99.1.40.462
2j4z626Aurora kinase A2.7.11.10.462
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.462
2yekEAMBromodomain-containing protein 2/0.462
3hl7I47Mitogen-activated protein kinase 14/0.462
3hyoADPPyridoxal kinase/0.462
3sf6FDAGlutaryl-CoA dehydrogenase/0.462
3uleC69Actin-related protein 3/0.462
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.462
4h1e10JBeta-secretase 13.4.23.460.462
4qmlANPSerine/threonine-protein kinase 242.7.11.10.462
5aacVGHALK tyrosine kinase receptor2.7.10.10.462
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.462
1ir3ANPInsulin receptor2.7.10.10.461
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.461
2lbaCHOFatty acid binding protein 6/0.461
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.461
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.461
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
3js2VM1Fibroblast growth factor receptor 1/0.461
3nglNAPBifunctional protein FolD/0.461
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.461
3ral04ZCyclin-dependent kinase 22.7.11.220.461
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.461
4bfxZVXPantothenate kinase2.7.1.330.461
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.461
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.461
5cnoANPEpidermal growth factor receptor2.7.10.10.461
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.460
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.460
2g226IGRenin3.4.23.150.460
2uzeC95Cyclin-dependent kinase 22.7.11.220.460
2vttLZDCyclin-dependent kinase 22.7.11.220.460
2zbaZBATrichothecene 3-O-acetyltransferase/0.460
3bqr4RBDeath-associated protein kinase 3/0.460
3g7jGTXGlutathione transferase GST1-4/0.460
3p62FMNPentaerythritol tetranitrate reductase/0.460
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.460
3pmy41LEndothiapepsin3.4.23.220.460
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.460
4a9mP9MBromodomain-containing protein 2/0.460
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.460
4kwi1TJReductase homolog/0.460
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.460
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.460
1bim0QBRenin3.4.23.150.459
1nooCAHCamphor 5-monooxygenase1.14.15.10.459
1thnADPAnti-sigma F factor/0.459
1vyw292Cyclin-dependent kinase 22.7.11.220.459
2b55D31Cyclin-dependent kinase 22.7.11.220.459
2en5SAHDiphthine synthase/0.459
3fr4F8AFatty acid-binding protein, adipocyte/0.459
3gwfFADCyclohexanone monooxygenase/0.459
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.459
3l8p0CEAngiopoietin-1 receptor2.7.10.10.459
3le62BZCyclin-dependent kinase 22.7.11.220.459
3o8gO8GHTH-type transcriptional regulator EthR/0.459
4j97ACPFibroblast growth factor receptor 2/0.459
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.459
4tuvCPZCytochrome P450 1191.140.459
1blzACVIsopenicillin N synthase1.21.3.10.458
1h74ADPHomoserine kinase2.7.1.390.458
1u4dDBQActivated CDC42 kinase 1/0.458
2bgiFADNADPH:ferredoxin reductase/0.458
2egbSAHDiphthine synthase/0.458
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.458
2iw84SPCyclin-dependent kinase 22.7.11.220.458
2w6nOA2Biotin carboxylase6.3.4.140.458
2wotZZGTGF-beta receptor type-12.7.11.300.458
3lq5SLQCyclin-dependent kinase 92.7.11.220.458
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.458
3vt5YI2Vitamin D3 receptor/0.458
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.458
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.458
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.458
1dr2TAPDihydrofolate reductase1.5.1.30.457
1oirHDYCyclin-dependent kinase 22.7.11.220.457
2b53D23Cyclin-dependent kinase 22.7.11.220.457
2bdyUNBProthrombin3.4.21.50.457
2e0aANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.457
2xvw9NRSerum albumin/0.457
3oafOAGDihydrofolate reductase1.5.1.30.457
3oqfS51Renin3.4.23.150.457
3psyRB9Endothiapepsin3.4.23.220.457
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.457
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.457
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.457
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.457
4lxhC1EAlpha/beta hydrolase fold/0.457
4nieNBHNuclear receptor ROR-gamma/0.457
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.457
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1k6pXN3Gag-Pol polyprotein3.4.23.160.456
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.456
2hekGDPUncharacterized protein/0.456
2jkoBIJFocal adhesion kinase 12.7.10.20.456
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.456
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.456
2znq401Peroxisome proliferator-activated receptor delta/0.456
3iok1P6Tyrosine-protein kinase JAK2/0.456
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.456
3qc9ADPRhodopsin kinase/0.456
3qwkX62Cyclin-dependent kinase 22.7.11.220.456
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.456
3zuyTCHTransporter/0.456
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.456
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.456
4irnFADAnaB/0.456
4ix6ADPUncharacterized protein/0.456
4j95ACPFibroblast growth factor receptor 2/0.456
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.456
1bsvNDPGDP-L-fucose synthase/0.455
1bygSTUTyrosine-protein kinase CSK/0.455
1eh4IC1Casein kinase I homolog 12.7.11.10.455
1hdrNADDihydropteridine reductase1.5.1.340.455
1i58ACPChemotaxis protein CheA2.7.13.30.455
1qxlFR8Adenosine deaminase3.5.4.40.455
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.455
2bu9HFVIsopenicillin N synthase1.21.3.10.455
2c3qGTXGlutathione S-transferase theta-12.5.1.180.455
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.455
2po7CHDFerrochelatase, mitochondrial4.99.1.10.455
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.455
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
2vw5BC6ATP-dependent molecular chaperone HSP82/0.455
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.455
2y6fM9FIsopenicillin N synthase1.21.3.10.455
3mdvCL6Cholesterol 24-hydroxylase/0.455
3q92XNBKetohexokinase/0.455
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.455
3qxpX64Cyclin-dependent kinase 22.7.11.220.455
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.455
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.455
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.455
4py6R78Bromodomain protein, putative/0.455
4pzdNAD3-Hydroxyacyl-CoA dehydrogenase/0.455
4qnaX11Serine/threonine-protein kinase 242.7.11.10.455
1dhrNADDihydropteridine reductase1.5.1.340.454
1fmjRTLRetinol dehydratase/0.454
1jtuLYBThymidylate synthase/0.454
1n83CLRNuclear receptor ROR-alpha/0.454
1tj0FADBifunctional protein PutA1.5.5.20.454
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.454
1zz2B11Mitogen-activated protein kinase 14/0.454
2egsSAHDiphthine synthase/0.454
2ejkSAHDiphthine synthase/0.454
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.454
2i40BLZCyclin-dependent kinase 22.7.11.220.454
2pb4SAHDiphthine synthase/0.454
2r2mI50Prothrombin3.4.21.50.454
2uzbC75Cyclin-dependent kinase 22.7.11.220.454
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.454
3fklFKLMitogen-activated protein kinase 14/0.454
3ke18292-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.454
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.454
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
3o3jBB4Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.454
4c58824Cyclin-G-associated kinase2.7.11.10.454
4ewhT77Activated CDC42 kinase 1/0.454
4hnf16WCasein kinase I isoform delta2.7.11.10.454
4nk92K5Fibroblast growth factor receptor 1/0.454
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.454
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.454
1a72PADAlcohol dehydrogenase E chain1.1.1.10.453
1phhFADp-hydroxybenzoate hydroxylase/0.453
1qiqACCIsopenicillin N synthase1.21.3.10.453
1z6tADPApoptotic protease-activating factor 1/0.453
2dr3ADPUPF0273 protein PH0284/0.453
2eh5SAHDiphthine synthase/0.453
2pmoHMDProtein kinase 7/0.453
2uxoTACHTH-type transcriptional regulator TtgR/0.453
2vkeTACTetracycline repressor protein class D/0.453
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.453
2wouZZFTGF-beta receptor type-12.7.11.300.453
2y6o1N1Ephrin type-A receptor 42.7.10.10.453
3ac1KZITyrosine-protein kinase Lck2.7.10.20.453
3cluFADElectron transfer flavoprotein subunit alpha/0.453
3drcMTXDihydrofolate reductase1.5.1.30.453
3dxmN24Actin-related protein 3/0.453
3fp0FP015-O-acetyltransferase/0.453
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.453
3nbvANPKetohexokinase/0.453
3pqbVGPPutative oxidoreductase/0.453
4b3aTACTetracycline repressor protein class D/0.453
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.453
4fkv61KCyclin-dependent kinase 22.7.11.220.453
4fkw62KCyclin-dependent kinase 22.7.11.220.453
4fx360KCyclin-dependent kinase 22.7.11.220.453
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.453
4jq7KJQEpidermal growth factor receptor2.7.10.10.453
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.453
3sn6P0GBeta-2 adrenergic receptor/0.453
1c4uIH1Prothrombin3.4.21.50.452
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.452
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1kzjCB3Thymidylate synthase/0.452
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.452
1p4fDRGDeath-associated protein kinase 12.7.11.10.452
1qrpHH0Pepsin A-43.4.23.10.452
1qy5NECEndoplasmin/0.452
1y7uCOAAcyl-CoA hydrolase/0.452
2am22LGUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.452
2vbdV10Isopenicillin N synthase1.21.3.10.452
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.452
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.452
2xb7GUIALK tyrosine kinase receptor2.7.10.10.452
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.452
2zjwREFCasein kinase II subunit alpha2.7.11.10.452
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.452
3ddw055Glycogen phosphorylase, liver form2.4.1.10.452
3fmh533Mitogen-activated protein kinase 14/0.452
3fr28CAFatty acid-binding protein, adipocyte/0.452
3i60E86Mitogen-activated protein kinase 12.7.11.240.452
3id8MRKGlucokinase2.7.1.20.452
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.452
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.452
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.452
3okxSAMS-adenosyl-L-methionine-binding protein RPA0152/0.452
3pdqKC6Lysine-specific demethylase 4A1.14.110.452
3rni21ZCyclin-dependent kinase 22.7.11.220.452
3t8oATPRhodopsin kinase/0.452
4bbe3O4Tyrosine-protein kinase JAK2/0.452
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.452
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.452
4mlp2CXCryptochrome-2/0.452
4o701QKBromodomain-containing protein 4/0.452
4pnmNU1Tankyrase-22.4.2.300.452
5a3cNADSIR2 family protein/0.452
5bt52LOBromodomain-containing protein 2/0.452
1gih1PUCyclin-dependent kinase 22.7.11.220.451
1gqtACPRibokinase/0.451
1mczRMNBenzoylformate decarboxylase4.1.1.70.451
1u54ACPActivated CDC42 kinase 1/0.451
1uy9PU6Heat shock protein HSP 90-alpha/0.451
1xddAAYIntegrin alpha-L/0.451
1yplRA8Prothrombin3.4.21.50.451
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.451
2bz5AB4Heat shock protein HSP 90-alpha/0.451
2iviACWIsopenicillin N synthase1.21.3.10.451
2p2qPRXAcetyl-coenzyme A synthetase/0.451
2uxpCLMHTH-type transcriptional regulator TtgR/0.451
2v7a627Tyrosine-protein kinase ABL12.7.10.20.451
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.451
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.451
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.451
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.451
4a81DXCMajor pollen allergen Bet v 1-A/0.451
4enhFVXCholesterol 24-hydroxylase/0.451
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.451
4jx1CAMCamphor 5-monooxygenase1.14.15.10.451
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.451
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.451
1dr3HBIDihydrofolate reductase1.5.1.30.450
1g5sI17Cyclin-dependent kinase 22.7.11.220.450
1h1q2A6Cyclin-dependent kinase 22.7.11.220.450
1iqrFADDeoxyribodipyrimidine photo-lyase4.1.99.30.450
1uzwCDHIsopenicillin N synthase1.21.3.10.450
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.450
2c5nCK8Cyclin-dependent kinase 22.7.11.220.450
2cchATPCyclin-dependent kinase 22.7.11.220.450
2ek2SAHDiphthine synthase/0.450
2g9uG27Glycogen phosphorylase, muscle form2.4.1.10.450
2i0v6C3Macrophage colony-stimulating factor 1 receptor2.7.10.10.450
2puiADPMethylthioribose kinase2.7.1.1000.450
2w4iVGAGlutamate racemase/0.450
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.450
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.450
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.450
3nynSGVG protein-coupled receptor kinase 62.7.11.160.450
4aacAAVMitogen-activated protein kinase 14/0.450
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4n9iPCGCatabolite expression activator/0.450
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.450
4y9rFADNADPH--cytochrome P450 reductase/0.450
5jscFADPutative acyl-CoA dehydrogenase/0.450
1cs4FOKAdenylate cyclase type 2/0.449
1cs4FOKAdenylate cyclase type 5/0.449
1hb1OCVIsopenicillin N synthase1.21.3.10.449
1kqnNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.449
2abbFMNPentaerythritol tetranitrate reductase/0.449
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.449
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
2d29FADAcyl-CoA dehydrogenase/0.449
2e16SAHDiphthine synthase/0.449
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.449
2i4qUA4Renin3.4.23.150.449
2j0j4STFocal adhesion kinase 12.7.10.20.449
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.449
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.449
2pzpACPFibroblast growth factor receptor 2/0.449
2woeAR6ADP-ribosyl-[dinitrogen reductase] glycohydrolase3.2.2.240.449
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.449
3bk2U5PRibonuclease J/0.449
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.449
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3fz1B98Cyclin-dependent kinase 22.7.11.220.449
3lqfNADGalactitol dehydrogenase/0.449
3mdmFJZCholesterol 24-hydroxylase/0.449
3tucFPWTyrosine-protein kinase SYK2.7.10.20.449
3w0gW07Vitamin D3 receptor/0.449
3w78CBDFMN-dependent NADH-azoreductase/0.449
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4fv7E94Mitogen-activated protein kinase 12.7.11.240.449
4fxy0W2Neurolysin, mitochondrial3.4.24.160.449
4g1z0VPVitamin D3 receptor A/0.449
4hnc0UTMandelate racemase/0.449
4jlk1NODeoxycytidine kinase2.7.1.740.449
4o4eATPKinase/0.449
4q72FADBifunctional protein PutA/0.449
4r7iSTIMacrophage colony-stimulating factor 1 receptor2.7.10.10.449
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1phgMYTCamphor 5-monooxygenase1.14.15.10.448
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.448
1t86CAMCamphor 5-monooxygenase1.14.15.10.448
1uykPUXHeat shock protein HSP 90-alpha/0.448
1v79FR7Adenosine deaminase3.5.4.40.448
1x1bSAHC-20 methyltransferase/0.448
1x2hLPALipoate-protein ligase A6.3.1.200.448
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
2csnCKICasein kinase I homolog 12.7.11.10.448
2emrSAHDiphthine synthase/0.448
2owkSAHDiphthine synthase/0.448
2p6kSAHDiphthine synthase/0.448
2qoqANPEphrin type-A receptor 32.7.10.10.448
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.448
2vgoAD5Aurora kinase B-A2.7.11.10.448
2w71L23Biotin carboxylase6.3.4.140.448
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.448
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.448
2yxuATPPyridoxal kinase2.7.1.350.448
3csoXNIGenome polyprotein2.7.7.480.448
3iaeD7KBenzaldehyde lyase/0.448
3isjA8DPantothenate synthetase6.3.2.10.448
3ivgFG5Pantothenate synthetase6.3.2.10.448
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.448
3mtfA3FActivin receptor type-12.7.11.300.448
3oev3OEProteasome subunit beta type-53.4.25.10.448
3oev3OEProteasome subunit beta type-63.4.25.10.448
3p9tTCLRepressor/0.448
3q3cNADNAD-dependent L-serine dehydrogenase/0.448
3qdzPRO_ALA_PRO_ARGProthrombin3.4.21.50.448
3qu0X40Cyclin-dependent kinase 22.7.11.220.448
3rk507ZCyclin-dependent kinase 22.7.11.220.448
3tp0FO5HTH-type transcriptional regulator EthR/0.448
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.448
4bcoT6QCyclin-dependent kinase 22.7.11.220.448
4bcpT3CCyclin-dependent kinase 22.7.11.220.448
4eok4SPCyclin-dependent kinase 22.7.11.220.448
4gk3L87Ephrin type-A receptor 32.7.10.10.448
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.448
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.448
4kb81QNCasein kinase I isoform delta2.7.11.10.448
5cvhADPCasein kinase II subunit alpha2.7.11.10.448
1culFOKAdenylate cyclase type 2/0.447
1culFOKAdenylate cyclase type 5/0.447
1h1s4SPCyclin-dependent kinase 22.7.11.220.447
1k6cMK1Gag-Pol polyprotein3.4.23.160.447
1nzdUPGDNA beta-glucosyltransferase/0.447
1oiuN76Cyclin-dependent kinase 22.7.11.220.447
1upw444Oxysterols receptor LXR-beta/0.447
1uyhPU0Heat shock protein HSP 90-alpha/0.447
1vrwNAIEnoyl-ACP reductase/0.447
2a0cCK9Cyclin-dependent kinase 22.7.11.220.447
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.447
2dekSAHDiphthine synthase/0.447
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.447
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.447
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.447
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
2igoFADPyranose 2-oxidase/0.447
2izuP01Casein kinase I isoform gamma-32.7.11.10.447
2pd7FADVivid PAS protein VVD/0.447
2pvnP63Casein kinase II subunit alpha2.7.11.10.447
2qblCAMCamphor 5-monooxygenase1.14.15.10.447
2v0uFMNNPH1-1/0.447
2vbpVB1Isopenicillin N synthase1.21.3.10.447
2xyuQ9GEphrin type-A receptor 42.7.10.10.447
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.447
3a783EVVitamin D3 receptor/0.447
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.447
3d75NBBPheromone-binding protein ASP1/0.447
3fhyATPPyridoxal kinase2.7.1.350.447
3ih0ANPUncharacterized sugar kinase PH14592.7.10.447
3p8jFMNPentaerythritol tetranitrate reductase/0.447
3r7iX9ICyclin-dependent kinase 22.7.11.220.447
3rak03ZCyclin-dependent kinase 22.7.11.220.447
3zkuHCVIsopenicillin N synthase1.21.3.10.447
4a862ANMajor pollen allergen Bet v 1-A/0.447
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.447
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.447
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.447
4mihFADPyranose 2-oxidase1.1.3.100.447
4qzuRTLRetinol-binding protein 2/0.447
4xj43ATCyclic GMP-AMP synthase/0.447
5drdATPAurora kinase A2.7.11.10.447
5kgpACOPredicted acetyltransferase/0.447
1bk0ACVIsopenicillin N synthase1.21.3.10.446
1bwsNDPGDP-L-fucose synthase/0.446
1d3dBZTProthrombin3.4.21.50.446
1y91CT9Cyclin-dependent kinase 22.7.11.220.446
2dv5SAHDiphthine synthase/0.446
2ek7SAHDiphthine synthase/0.446
2emuSAHDiphthine synthase/0.446
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.446
2ijmATPFocal adhesion kinase 12.7.10.20.446
2owuSAHDiphthine synthase/0.446
2pvlP55Casein kinase II subunit alpha2.7.11.10.446
2uzdC85Cyclin-dependent kinase 22.7.11.220.446
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.446
3clrFADElectron transfer flavoprotein subunit alpha/0.446
3hmm855TGF-beta receptor type-12.7.11.300.446
3ik6HCZGlutamate receptor 2/0.446
3keuATPPyridoxal kinase2.7.1.350.446
3lxiCAMCytochrome P450/0.446
3oom507Activin receptor type-12.7.11.300.446
3pvcFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC/0.446
3rk708ZCyclin-dependent kinase 22.7.11.220.446
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.446
3uvr06FMitogen-activated protein kinase 14/0.446
3zh8C58Protein kinase C iota type2.7.11.130.446
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.446
4bj9UHBTankyrase-22.4.2.300.446
4ead0NPThymidine phosphorylase2.4.2.40.446
4g1d0VKVitamin D3 receptor A/0.446
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.446
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.446
4l8u9AZSerum albumin/0.446
4l9i8PRRhodopsin kinase/0.446
4l9q9TPSerum albumin/0.446
5dmhADP3-oxo-tetronate kinase/0.446
1drhNAPDihydrofolate reductase1.5.1.30.445
1gvt2ZSEndothiapepsin3.4.23.220.445
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
1hb3SCVIsopenicillin N synthase1.21.3.10.445
1nhhANPDNA mismatch repair protein MutL/0.445
1nq7ARLNuclear receptor ROR-beta/0.445
1phePIYCamphor 5-monooxygenase1.14.15.10.445
1q1wFADPutidaredoxin reductase1.18.1.50.445
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.445
1z0aGDPRas-related protein Rab-2A/0.445
1zdwFLVPrenyltransferase/0.445
2bxqIMNSerum albumin/0.445
2c6tDT5Cyclin-dependent kinase 22.7.11.220.445
2dxwSAHDiphthine synthase/0.445
2gblATPCircadian clock protein kinase KaiC2.7.11.10.445
2gpuOHTEstrogen-related receptor gamma/0.445
2hog710Serine/threonine-protein kinase Chk12.7.11.10.445
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.445
2pcaSAHDiphthine synthase/0.445
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.445
2py3ACPFibroblast growth factor receptor 2/0.445
2rg5279Mitogen-activated protein kinase 14/0.445
2v5aLZLBiotin carboxylase6.3.4.140.445
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.445
2xviFADPutative flavin-containing monooxygenase/0.445
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.445
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3jpuTY4Transcriptional activator protein LasR/0.445
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.445
4a802ANMajor pollen allergen Bet v 1-A/0.445
4b8zNAPGDP-L-fucose synthase1.1.1.2710.445
4brxKGWFocal adhesion kinase 12.7.10.20.445
4f9b0SYCell division cycle 7-related protein kinase2.7.11.10.445
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.445
4k8aK8AFocal adhesion kinase 12.7.10.20.445
4m9aFDAAcyl-CoA dehydrogenase/0.445
4xgxADPFAD:protein FMN transferase/0.445
5aaaVGHALK tyrosine kinase receptor2.7.10.10.445
5k2aZMAAdenosine receptor A2a/0.445
1bxoPP7Penicillopepsin-13.4.23.200.444
1jioDEB6-deoxyerythronolide B hydroxylase/0.444
1nm6L86Prothrombin3.4.21.50.444
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1rbyKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.444
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.444
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.444
2c29NAPDihydroflavonol 4-reductase/0.444
2e7zMGDAcetylene hydratase/0.444
2eh2SAHDiphthine synthase/0.444
2eleSAHDiphthine synthase/0.444
2hcdBIVVitamin D3 receptor A/0.444
2jh5895Prothrombin3.4.21.50.444
2uxuNARHTH-type transcriptional regulator TtgR/0.444
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.444
2y60M8FIsopenicillin N synthase1.21.3.10.444
3ad9NADSubunit alpha of sarocosine oxidase/0.444
3adaNADSubunit alpha of sarocosine oxidase/0.444
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3cukFADD-amino-acid oxidase1.4.3.30.444
3dmhSAMProbable ribosomal RNA small subunit methyltransferase/0.444
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.444
3il1B5DGlutamate receptor 2/0.444
3imgBZ3Pantothenate synthetase6.3.2.10.444
3iodA6DPantothenate synthetase6.3.2.10.444
3ivxFG6Pantothenate synthetase6.3.2.10.444
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.444
3oibFDAPutative acyl-CoA dehydrogenase/0.444
3orfNADDihydropteridine reductase1.5.1.340.444
3pwwROCEndothiapepsin3.4.23.220.444
3sheI85MAP kinase-activated protein kinase 32.7.11.10.444
3uzp0CKCasein kinase I isoform delta2.7.11.10.444
3wtkTH4Acetylcholine-binding protein/0.444
4aa5NQBMitogen-activated protein kinase 14/0.444
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.444
4ejh0QACytochrome P450 2A131.14.14.10.444
4eol1ROCyclin-dependent kinase 22.7.11.220.444
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.444
4fob0USALK tyrosine kinase receptor2.7.10.10.444
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.444
4ih8B43Calmodulin-domain protein kinase 1/0.444
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.444
4r20AERCytochrome P450 family 17 polypeptide 2/0.444
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
4v010LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b/0.444
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.444
4wkqIREEpidermal growth factor receptor2.7.10.10.444
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.444
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.444
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.444
5a3bAPRSIR2 family protein/0.444
5auuLU2Death-associated protein kinase 12.7.11.10.444
5av3KMPDeath-associated protein kinase 12.7.11.10.444
1c1dNAIPhenylalanine dehydrogenase/0.443
1dr3TAPDihydrofolate reductase1.5.1.30.443
1finATPCyclin-dependent kinase 22.7.11.220.443
1fmlRTLRetinol dehydratase/0.443
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.443
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.443
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.443
1wn3HXCPhenylacetic acid degradation protein PaaI/0.443
1y6oMJIPhospholipase A2, major isoenzyme3.1.1.40.443
2a1oCAMCamphor 5-monooxygenase1.14.15.10.443
2h55DZ8Heat shock protein HSP 90-alpha/0.443
2pcmSAHDiphthine synthase/0.443
2pz5ACPFibroblast growth factor receptor 2/0.443
2rkvZBATrichothecene 3-O-acetyltransferase/0.443
2v00V15Endothiapepsin3.4.23.220.443
2xpvMIYTetracycline repressor protein class D/0.443
3b6pTMPThree-prime repair exonuclease 13.1.11.20.443
3b70NAPEnoyl reductase LovC10.443
3flyFLYMitogen-activated protein kinase 14/0.443
3lkhLT6Genome polyprotein2.7.7.480.443
3lxkMI1Tyrosine-protein kinase JAK32.7.10.20.443
3mvm39PMitogen-activated protein kinase 14/0.443
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.443
3nnuEDBMitogen-activated protein kinase 14/0.443
3qqgX06Cyclin-dependent kinase 22.7.11.220.443
3qwc98PProthrombin3.4.21.50.443
3r1yX76Cyclin-dependent kinase 22.7.11.220.443
3ukuC69Actin-related protein 3/0.443
3vt3VDXVitamin D3 receptor/0.443
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.443
3wmxNADNAD dependent epimerase/dehydratase/0.443
4aua4AUCyclin-dependent kinase 62.7.11.220.443
4c61LMMTyrosine-protein kinase JAK2/0.443
4flpJQ1Bromodomain testis-specific protein/0.443
4lcf1WLUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.443
4looSB4Mitogen-activated protein kinase 14/0.443
4r1lADPPhenylacetate-coenzyme A ligase/0.443
5auwQUEDeath-associated protein kinase 12.7.11.10.443
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1j39UPGDNA beta-glucosyltransferase/0.442
1m17AQ4Epidermal growth factor receptor2.7.10.10.442
1oytFSNProthrombin3.4.21.50.442
1q19SSCCarbapenam-3-carboxylate synthase6.3.3.60.442
1rkhVD2Vitamin D3 receptor/0.442
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.442
1uy7PU4Heat shock protein HSP 90-alpha/0.442
1vbnYSATyrosine--tRNA ligase6.1.1.10.442
1vyrFMNPentaerythritol tetranitrate reductase/0.442
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.442
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.442
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.442
2ahvCOAAcetate CoA-transferase YdiF2.8.3.80.442
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.442
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.442
2pmdGNPTranslation initiation factor 2 subunit gamma/0.442
2x9dITCTetracycline repressor protein class D/0.442
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.442
3bgxMEFThymidylate synthase/0.442
3bw2FMNPutative 2-nitropropane dioxygenase/0.442
3cgbCOACoenzyme A disulfide reductase/0.442
3d7kD7KBenzaldehyde lyase/0.442
3ezrEZRCyclin-dependent kinase 22.7.11.220.442
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
3fhxPLPPyridoxal kinase2.7.1.350.442
3ggfGVDSerine/threonine-protein kinase 26/0.442
3jzfJZKBiotin carboxylase6.3.4.140.442
3kb6NADD-lactate dehydrogenase/0.442
3lshFADPyranose 2-oxidase/0.442
3ocgOCGMitogen-activated protein kinase 14/0.442
3oriAGSSerine/threonine protein kinase/0.442
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.442
3qtv06PProthrombin3.4.21.50.442
3r7vZ02Cyclin-dependent kinase 22.7.11.220.442
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.442
3uwqU5POrotidine 5'-phosphate decarboxylase/0.442
3w9rA8SAbscisic acid receptor PYL9/0.442
4c62XWWTyrosine-protein kinase JAK2/0.442
4f9c0SXCell division cycle 7-related protein kinase2.7.11.10.442
4jlj1NMDeoxycytidine kinase2.7.1.740.442
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.442
4rrrA3TThreonine--tRNA ligase6.1.1.30.442
4wudANPDNA gyrase subunit B/0.442
4ypuSAMHistone-lysine N-methyltransferase ASH1L2.1.1.430.442
5a8aFMNRiboflavin biosynthesis protein RibF2.7.1.260.442
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
5dp2NAPCurF/0.442
5epeSAHUncharacterized protein/0.442
1kvoOAPPhospholipase A2, membrane associated/0.441
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.441
1t2cNAIL-lactate dehydrogenase1.1.1.270.441
1w87NAPFerredoxin--NADP reductase1.18.1.20.441
1ywrLI9Mitogen-activated protein kinase 14/0.441
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.441
2bxmIMNSerum albumin/0.441
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.441
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.441
2gtnLIEMitogen-activated protein kinase 14/0.441
2ojg19AMitogen-activated protein kinase 12.7.11.240.441
2oorNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.441
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
2r1rTTPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.441
2uzoC62Cyclin-dependent kinase 22.7.11.220.441
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.441
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.441
2ykeYKEHeat shock protein HSP 90-alpha/0.441
3bbrBHYGlutamate receptor 2/0.441
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
3h3jNADL-lactate dehydrogenase 11.1.1.270.441
3iocA5DPantothenate synthetase6.3.2.10.441
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.441
3nbwTR4Ketohexokinase/0.441
3s1h56ZCyclin-dependent kinase 22.7.11.220.441
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.441
3v0o4GWHisto-blood group ABO system transferase/0.441
3w32W32Epidermal growth factor receptor2.7.10.10.441
3w551FMMitogen-activated protein kinase 12.7.11.240.441
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.441
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4az29MUProthrombin3.4.21.50.441
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.441
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.441
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.441
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.441
4hy6FJ1Heat shock protein HSP 90-alpha/0.441
4ia1BIVVitamin D3 receptor A/0.441
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.441
4kbc1QJCasein kinase I isoform delta2.7.11.10.441
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4n57ADPAPH(2'')-Id/0.441
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.441
4y1bNAPAntE/0.441
1coyANDCholesterol oxidase1.1.3.60.440
1dirNADDihydropteridine reductase1.5.1.340.440
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.440
1fwyUD1Bifunctional protein GlmU/0.440
1h7wFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.440
1hfqMOTDihydrofolate reductase1.5.1.30.440
1ia1NDPDihydrofolate reductase1.5.1.30.440
1nzfUPGDNA beta-glucosyltransferase/0.440
1ownFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1tvcFDAMethane monooxygenase component C1.14.13.250.440
1u7tTDT3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.440
1ypkCCRProthrombin3.4.21.50.440
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.440
2bbqPFGThymidylate synthase/0.440
2bunFADAppA protein/0.440
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.440
2e8qSAHDiphthine synthase/0.440
2ej2PPEBranched-chain amino acid aminotransferase (IlvE)/0.440
2g8yNADHydroxycarboxylate dehydrogenase B/0.440
2iwsNP4ATP-dependent molecular chaperone HSP82/0.440
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.440
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.440
2xlrFADPutative flavin-containing monooxygenase/0.440
2yemWSHBromodomain-containing protein 4/0.440
2ykbYKBHeat shock protein HSP 90-alpha/0.440
2yr5FADPhenylalanine 2-monooxygenase precursor1.13.12.90.440
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.440
3a62STURibosomal protein S6 kinase beta-12.7.11.10.440
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.440
3cgdCOACoenzyme A disulfide reductase/0.440
3cppCAMCamphor 5-monooxygenase1.14.15.10.440
3gu83GUDeath-associated protein kinase 12.7.11.10.440
3oyzACOMalate synthase2.3.3.90.440
3pxyJWSCyclin-dependent kinase 22.7.11.220.440
3ut5LOCTubulin beta chain/0.440
3wleNAD(R)-specific carbonyl reductase/0.440
4b8mVX6Aurora kinase B-A2.7.11.10.440
4bb3KKAIsopenicillin N synthase1.21.3.10.440
4bb432WEphrin type-B receptor 42.7.10.10.440
4bjx73BBromodomain-containing protein 4/0.440
4ez8DHFThymidylate synthase2.1.1.450.440
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.440
4g210VPVitamin D3 receptor A/0.440
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.440
4jxrACOAcetyltransferase/0.440
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.440
4o74R78Bromodomain-containing protein 4/0.440
4ocvANPAminoglycoside phosphotransferase/0.440
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.440
4r81FMNPredicted NADH dehydrogenase/0.440
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
4y3jHICEndothiapepsin3.4.23.220.440
5bp7SAHSAM-dependent methyltransferase/0.440