sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.869 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.768 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.767 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.764 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.754 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.753 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.751 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.750 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.748 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.742 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.739 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.739 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.736 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.729 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.728 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.719 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.719 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.717 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.700 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.695 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.667 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.667 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.597 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.580 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.580 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.580 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.568 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.559 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.559 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.559 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.551 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.550 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.541 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.540 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.539 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.534 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.534 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.525 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.521 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.520 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.510 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.507 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.506 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.506 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.501 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.501 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.498 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.498 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.497 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.496 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.496 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.496 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.495 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.495 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.495 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.495 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.494 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.493 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.493 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.492 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.491 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.491 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.488 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.488 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.488 | |
| 1swt | BTN | Streptavidin | / | 0.487 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.487 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.487 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.487 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.486 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.485 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.485 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.485 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.484 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.484 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.484 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.483 | |
| 2avi | BTN | Avidin | / | 0.483 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.483 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.483 | |
| 4e2d | FMN | Dehydrogenase | / | 0.483 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.483 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.481 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.481 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.481 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.481 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.480 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.480 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.480 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.480 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.480 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.480 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.480 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.479 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.479 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.479 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.479 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.479 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.479 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.479 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.478 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.478 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.478 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.477 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.477 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.477 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.477 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.477 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.477 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.477 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.476 | |
| 1v5z | 2HC | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.476 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.476 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.476 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.476 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.476 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.476 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.476 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.476 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.474 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.474 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.474 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.474 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.474 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.474 | |
| 1zdw | FLV | Prenyltransferase | / | 0.473 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.473 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.473 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.473 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.472 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.472 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.472 | |
| 4bxk | 1IU | Angiotensin-converting enzyme | 3.2.1 | 0.472 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.472 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.472 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.471 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.471 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.471 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.471 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.471 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.471 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.470 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.470 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.470 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.470 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.470 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.470 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.470 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.469 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.469 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.469 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.469 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.468 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.468 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.468 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.468 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.468 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.468 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.468 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.467 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.467 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.467 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.467 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.467 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.467 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.467 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.467 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 3u9e | COA | Lmo1369 protein | / | 0.467 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.467 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.467 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.466 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.466 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.466 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.466 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.466 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.466 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.466 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.466 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.465 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.465 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.465 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.465 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.465 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.465 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.465 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.464 | |
| 1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.464 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.464 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.464 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.464 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.464 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.464 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.464 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.464 | |
| 4iah | 1DX | Alr2278 protein | / | 0.464 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.463 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.463 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.463 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.463 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.463 | |
| 2izh | BTN | Streptavidin | / | 0.463 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.463 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.463 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.463 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.462 | |
| 1i9h | BNI | Streptavidin | / | 0.462 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.462 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.462 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.462 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.462 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.462 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.462 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.461 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.461 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.461 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.461 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.461 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.461 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.461 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.461 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.460 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.460 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.460 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.460 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.460 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.460 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.460 | |
| 4j49 | 1J1 | Uncharacterized protein | / | 0.460 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.460 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.459 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.459 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.459 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.459 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.459 | |
| 2r5n | TPP | Transketolase 1 | / | 0.459 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.459 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.459 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.459 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.459 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.459 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.458 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.458 | |
| 1gvr | TNL | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.458 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.458 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.458 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.458 | |
| 4js1 | CTN | Beta-galactoside alpha-2,6-sialyltransferase 1 | 2.4.99.1 | 0.458 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.458 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.458 | |
| 1qtq | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.457 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.457 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.457 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.457 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.457 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 3iog | SDF | Metallo-beta-lactamase type 2 | / | 0.457 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.457 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.457 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.456 | |
| 1fki | SB1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.456 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.456 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.456 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.456 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.456 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.456 | |
| 2ohv | NHL | Glutamate racemase | / | 0.456 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.456 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.456 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.456 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.456 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 3ie3 | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.456 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.456 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 3qvi | K95 | HAP protein | / | 0.456 | |
| 3vp6 | HLD | Glutamate decarboxylase 1 | 4.1.1.15 | 0.456 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4e2b | FMN | Dehydrogenase | / | 0.456 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.456 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.456 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.455 | |
| 1lcw | SHM | Streptavidin | / | 0.455 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.455 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.455 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.455 | |
| 1s4o | GDP | Glycolipid 2-alpha-mannosyltransferase | / | 0.455 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.455 | |
| 2bp1 | NDP | Aflatoxin B1 aldehyde reductase member 2 | / | 0.455 | |
| 2c4i | BTN | Avidin | / | 0.455 | |
| 2dsg | SAH | Diphthine synthase | / | 0.455 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.455 | |
| 2rtd | BTN | Streptavidin | / | 0.455 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.455 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.455 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.455 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.455 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.455 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.455 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.455 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.455 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.455 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.455 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.454 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.454 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.454 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.454 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.454 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.454 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.454 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.454 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.454 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.454 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.454 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.454 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.454 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.454 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.454 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.454 | |
| 1gad | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.453 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.453 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.453 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2rte | BTN | Streptavidin | / | 0.453 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.453 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.453 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.453 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.453 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.453 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.453 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.453 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.453 | |
| 4jva | 1OR | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.453 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.453 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.452 | |
| 1eio | GCH | Gastrotropin | / | 0.452 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.452 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.452 | |
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.452 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.452 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.452 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.452 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.452 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.452 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.452 | |
| 4gda | BTN | Streptavidin | / | 0.452 | |
| 4hms | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.452 | |
| 4iae | 1DX | Alr2278 protein | / | 0.452 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.452 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.452 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.452 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.451 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.451 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.451 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.451 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1qzy | TDE | Methionine aminopeptidase 2 | / | 0.451 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.451 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.451 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.451 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.451 | |
| 2j08 | IRF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.451 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.451 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2y3p | SM8 | DNA gyrase subunit A | / | 0.451 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.451 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.451 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.451 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.451 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.451 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.451 | |
| 4y1b | NAP | AntE | / | 0.451 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.451 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.450 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.450 | |
| 1ffy | MRC | Isoleucine--tRNA ligase | 6.1.1.5 | 0.450 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.450 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.450 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.450 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.450 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.450 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.450 | |
| 2ejk | SAH | Diphthine synthase | / | 0.450 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.450 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.450 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.450 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.450 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.450 | |
| 4avl | TMP | Polymerase acidic protein | / | 0.450 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.450 | |
| 4pne | SAH | Methyltransferase-like protein | / | 0.450 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.450 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.449 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.449 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.449 | |
| 1stp | BTN | Streptavidin | / | 0.449 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.449 | |
| 1y1r | ANU | Uridine phosphorylase | 2.4.2.3 | 0.449 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.449 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 2emr | SAH | Diphthine synthase | / | 0.449 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.449 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.449 | |
| 2rto | IMI | Streptavidin | / | 0.449 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.449 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.449 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.449 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.449 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.449 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4rnx | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.449 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.448 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.448 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.448 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.448 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.448 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.448 | |
| 2bxq | IMN | Serum albumin | / | 0.448 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.448 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.448 | |
| 2dra | ATP | CCA-adding enzyme | 2.7.7.72 | 0.448 | |
| 2e07 | SAH | Diphthine synthase | / | 0.448 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.448 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.448 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.448 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.448 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.448 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.448 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.448 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.448 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.448 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 4jic | FMN | GTN Reductase | / | 0.448 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.448 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.448 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.448 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.448 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.447 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.447 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.447 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.447 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.447 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.447 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.447 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.447 | |
| 2po3 | T4K | 4-dehydrase | / | 0.447 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
| 2rtk | GLL | Streptavidin | / | 0.447 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.447 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.447 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.447 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.447 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.447 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.447 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.447 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.447 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.446 | |
| 1swg | BTN | Streptavidin | / | 0.446 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.446 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1xvt | COA | L-carnitine CoA-transferase | / | 0.446 | |
| 2e15 | SAH | Diphthine synthase | / | 0.446 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.446 | |
| 2hej | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.446 | |
| 2izl | IMI | Streptavidin | / | 0.446 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.446 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.446 | |
| 2wbg | LGS | Beta-glucosidase A | 3.2.1.21 | 0.446 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3fun | 798 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.446 | |
| 3v2u | ATP | Protein GAL3 | / | 0.446 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.446 | |
| 4rel | KMP | Glycosyltransferase | / | 0.446 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.446 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.445 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.445 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1til | ATP | Anti-sigma F factor | / | 0.445 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.445 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.445 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.445 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.445 | |
| 2ofi | ADK | 3-methyladenine DNA glycosylase I | / | 0.445 | |
| 2rfi | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.445 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.445 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.445 | |
| 3e23 | SAM | Uncharacterized protein | / | 0.445 | |
| 3e6e | DCS | Alanine racemase | / | 0.445 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.445 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3nt4 | NAI | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.445 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.445 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.445 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.445 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.445 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.445 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.445 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.445 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.445 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 1i2c | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.444 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1jf0 | CZH | Obelin | / | 0.444 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1qrt | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.444 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.444 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.444 | |
| 2emu | SAH | Diphthine synthase | / | 0.444 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.444 | |
| 2izg | BTN | Streptavidin | / | 0.444 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.444 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.444 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.444 | |
| 2rtf | BTN | Streptavidin | / | 0.444 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.444 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.444 | |
| 3pft | FMN | Flavin reductase | / | 0.444 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.444 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.444 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.444 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.444 | |
| 9gss | GTX | Glutathione S-transferase P | 2.5.1.18 | 0.444 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.443 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.443 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.443 | |
| 1owk | 303 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.443 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 2a5c | 8DA | Avidin | / | 0.443 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.443 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.443 | |
| 2pch | SAH | Diphthine synthase | / | 0.443 | |
| 2rtn | IMI | Streptavidin | / | 0.443 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.443 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.443 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 3b9l | AZZ | Serum albumin | / | 0.443 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.443 | |
| 3nxq | RX4 | Angiotensin-converting enzyme | 3.2.1 | 0.443 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.443 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.443 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.443 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.443 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.442 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.442 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.442 | |
| 1qru | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.442 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.442 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.442 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.442 | |
| 2izj | BTN | Streptavidin | / | 0.442 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2wzw | FMN | Nitroreductase NfnB | / | 0.442 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.442 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.442 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.442 | |
| 3p0h | FSE | Putative tyrosyl-tRNA synthetase | / | 0.442 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.442 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.442 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.442 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.442 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.442 | |
| 4iaw | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.442 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.442 | |
| 4lb9 | EVP | Serum albumin | / | 0.442 | |
| 4n1g | CEI | Obelin | / | 0.442 | |
| 5dp2 | NAP | CurF | / | 0.442 | |
| 4u15 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.442 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.441 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.441 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.441 | |
| 1vce | SAH | Diphthine synthase | / | 0.441 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.441 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.441 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.441 | |
| 2j09 | FMN | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.441 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.441 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.441 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.441 | |
| 3c1o | NAP | Eugenol synthase | / | 0.441 | |
| 3eo8 | FMN | Putative nitroreductase | / | 0.441 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.441 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.441 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.441 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.441 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.441 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.441 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.441 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.441 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.441 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.441 | |
| 4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.441 | |
| 4to0 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.441 | |
| 4tyq | AP5 | Adenylate kinase | / | 0.441 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 13gs | SAS | Glutathione S-transferase P | 2.5.1.18 | 0.440 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.440 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.440 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.440 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.440 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 2dxv | SAH | Diphthine synthase | / | 0.440 | |
| 2e8q | SAH | Diphthine synthase | / | 0.440 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.440 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.440 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.440 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.440 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.440 | |
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 | 0.440 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.440 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.440 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4h0v | NAD | Iota toxin component Ia | / | 0.440 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.440 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.440 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.440 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.440 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.440 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.440 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.440 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.440 |