sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1wk8 | VMS | Isoleucine--tRNA ligase | 6.1.1.5 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1wk8 | VMS | Isoleucine--tRNA ligase | 6.1.1.5 | 1.000 | |
| 1wnz | 2VA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.600 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.515 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.510 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.501 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.499 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.497 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.496 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.495 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.493 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.492 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.492 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.492 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.492 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.491 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.491 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.490 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.490 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.490 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.490 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.490 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.489 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.486 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.486 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.485 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.485 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.485 | |
| 5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.485 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.483 | |
| 4u7w | NDP | MxaA | / | 0.483 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.482 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.482 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.482 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.482 | |
| 1u30 | GOX | Pancreatic alpha-amylase | / | 0.481 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.481 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.481 | |
| 4l4x | NDP | AmphI | / | 0.481 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.480 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.479 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.479 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.479 | |
| 3c1o | NAP | Eugenol synthase | / | 0.479 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.479 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.479 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.478 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.478 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.478 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.478 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.478 | |
| 5cyo | GDP | Septin-9 | / | 0.478 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.477 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.477 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.477 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.477 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.476 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.476 | |
| 2py7 | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.476 | |
| 3gon | ANP | Phosphomevalonate kinase | / | 0.476 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.475 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.475 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.475 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.475 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.475 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.474 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.474 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.474 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.474 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.474 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.474 | |
| 4dxd | 9PC | Cell division protein FtsZ | / | 0.474 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.474 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.473 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.473 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.472 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.472 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.472 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.472 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.472 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.471 | |
| 2j09 | FMN | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.471 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.471 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.471 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.471 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.471 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.471 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.470 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.470 | |
| 2ohv | NHL | Glutamate racemase | / | 0.470 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.470 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.470 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.470 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.470 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.470 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.470 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.470 | |
| 4l6s | 1WQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.470 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.469 | |
| 1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.469 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.469 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 2y5s | 78H | Dihydropteroate synthase | / | 0.469 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.469 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.469 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.469 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.468 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.468 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.468 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.468 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.468 | |
| 4yqf | GDP | Septin-9 | / | 0.468 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.467 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.467 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.467 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.466 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 1yp3 | ATP | Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic | 2.7.7.27 | 0.466 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.466 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.466 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.466 | |
| 3psy | RB9 | Endothiapepsin | 3.4.23.22 | 0.466 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.466 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.466 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.466 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 3a3g | DLZ | Lumazine protein | / | 0.465 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.465 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.465 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.465 | |
| 3lpg | Z78 | Beta-glucuronidase | 3.2.1.31 | 0.465 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.465 | |
| 3zhy | FM6 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.465 | |
| 4ceq | QCH | Integrase | / | 0.465 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.464 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.464 | |
| 2cdu | FAD | NADH oxidase | / | 0.464 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.464 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.464 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.464 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.464 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.464 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.464 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.464 | |
| 4cf1 | IY7 | Integrase | / | 0.464 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.464 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.464 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.464 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.463 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.463 | |
| 1em6 | CP4 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.463 | |
| 1p4a | PCP | Pur operon repressor | / | 0.463 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.463 | |
| 2ejz | SAH | Diphthine synthase | / | 0.463 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.463 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.463 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.463 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3dzv | ADP | Hydroxyethylthiazole kinase | / | 0.463 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.463 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.463 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.463 | |
| 5itz | GTP | Tubulin alpha-1B chain | / | 0.463 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.462 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.462 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.462 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.462 | |
| 3eku | CY9 | Actin-5C | / | 0.462 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.462 | |
| 3t6i | NC9 | Endothiapepsin | 3.4.23.22 | 0.462 | |
| 4e2d | FMN | Dehydrogenase | / | 0.462 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.462 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.462 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.462 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.461 | |
| 1u33 | LM2 | Pancreatic alpha-amylase | / | 0.461 | |
| 1zji | 2PG | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.461 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.461 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.461 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.461 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.461 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.461 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.461 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.461 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3rn8 | RN8 | Glutamate receptor 2 | / | 0.461 | |
| 4ajb | TAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.461 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4hmv | WUB | Phenazine biosynthesis protein PhzG | 1.4 | 0.461 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.461 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.460 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.460 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.460 | |
| 1pzh | NAD | Lactate dehydrogenase | / | 0.460 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.460 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.460 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.460 | |
| 2r5n | TPP | Transketolase 1 | / | 0.460 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.460 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.460 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3ggc | H26 | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.460 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.460 | |
| 3wwm | ADP | [LysW]-aminoadipate kinase | / | 0.460 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.460 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.460 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.460 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.460 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.460 | |
| 4py2 | 43E | Methionine--tRNA ligase | / | 0.460 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.460 | |
| 5aga | ANP | DNA polymerase theta | / | 0.460 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.459 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.459 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.459 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.459 | |
| 1qy5 | NEC | Endoplasmin | / | 0.459 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.459 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.459 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.459 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.459 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.459 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.459 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3tdj | 3TJ | Glutamate receptor 2 | / | 0.459 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.459 | |
| 4zea | IMI | Endothiapepsin | 3.4.23.22 | 0.459 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.458 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.458 | |
| 1pw1 | HEL | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.458 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.458 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.458 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.458 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.458 | |
| 4ajp | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.458 | |
| 4cfb | OM3 | Integrase | / | 0.458 | |
| 4chq | CWU | Integrase | / | 0.458 | |
| 4e2b | FMN | Dehydrogenase | / | 0.458 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.458 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.458 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.457 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.457 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.457 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.457 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.457 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.457 | |
| 3eks | CY9 | Actin-5C | / | 0.457 | |
| 3fzf | ATP | Heat shock cognate 71 kDa protein | / | 0.457 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.457 | |
| 3mje | NDP | AmphB | / | 0.457 | |
| 3o3j | BB4 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.457 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.457 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.457 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.457 | |
| 1bp6 | UMP | Thymidylate synthase | / | 0.456 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.456 | |
| 1zp4 | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.456 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.456 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.456 | |
| 3b2e | ADP | ATPase GET3 | / | 0.456 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.456 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.456 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3lst | SAH | CalO1 | / | 0.456 | |
| 4die | C5P | Cytidylate kinase | / | 0.456 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4h6p | FMN | Chromate reductase | / | 0.456 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.456 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.455 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.455 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.455 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.455 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.455 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.455 | |
| 2b56 | UTP | RNA editing complex protein MP57 | / | 0.455 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.455 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.455 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.455 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.455 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.455 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.455 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.455 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.455 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.455 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.455 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.454 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.454 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.454 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 2dra | ATP | CCA-adding enzyme | 2.7.7.72 | 0.454 | |
| 2ej2 | PPE | Branched-chain amino acid aminotransferase (IlvE) | / | 0.454 | |
| 2gqp | PA7 | Endoplasmin | / | 0.454 | |
| 2pja | 33Z | Carboxypeptidase B | / | 0.454 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.454 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.454 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.454 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.454 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.454 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.454 | |
| 4rvd | SAM | D-mycarose 3-C-methyltransferase | / | 0.454 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.454 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.454 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1ek6 | UPG | UDP-glucose 4-epimerase | / | 0.453 | |
| 1f4e | TPR | Thymidylate synthase | / | 0.453 | |
| 1kuy | COT | Serotonin N-acetyltransferase | / | 0.453 | |
| 1nlm | UD1 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | / | 0.453 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.453 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.453 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.453 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.453 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.453 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.453 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.453 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.453 | |
| 3t0i | SAH | Putative methyltransferase | / | 0.453 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.453 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.453 | |
| 4cfa | WOP | Integrase | / | 0.453 | |
| 4hs4 | FMN | Chromate reductase | / | 0.453 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.453 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.453 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.453 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.452 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.452 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.452 | |
| 1kzk | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1mma | ADP | Myosin-2 heavy chain | / | 0.452 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.452 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.452 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.452 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.452 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2ibz | UQ6 | Cytochrome b | / | 0.452 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.452 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.452 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.452 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.452 | |
| 3ftx | RE2 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.452 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.452 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 4blr | UTP | NTPase P4 | / | 0.452 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.452 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4h4w | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.452 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.452 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.452 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.452 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.452 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.451 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.451 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.451 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.451 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.451 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.451 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.451 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.451 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 1wng | SAH | Diphthine synthase | / | 0.451 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.451 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.451 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.451 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.451 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.451 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.451 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.451 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.451 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.451 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.451 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.451 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.451 | |
| 4pgt | GBX | Glutathione S-transferase P | 2.5.1.18 | 0.451 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.451 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.451 | |
| 4ykl | GMP | Aprataxin-like protein | 3 | 0.451 | |
| 5c48 | URM | Histo-blood group ABO system transferase | / | 0.451 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.451 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.450 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.450 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.450 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.450 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.450 | |
| 2r8o | T5X | Transketolase 1 | / | 0.450 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.450 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.450 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.450 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.450 | |
| 3to0 | FMN | Iodotyrosine deiodinase 1 | 1.21.1.1 | 0.450 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.450 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4gsu | DWZ | L,D-transpeptidase 2 | 2.3.2 | 0.450 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.450 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.450 | |
| 4u0m | ATP | Cyclic GMP-AMP synthase | / | 0.450 | |
| 4yd7 | F5N | Endothiapepsin | 3.4.23.22 | 0.450 | |
| 5a3b | APR | SIR2 family protein | / | 0.450 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.450 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.449 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.449 | |
| 1e82 | M90 | Endothiapepsin | 3.4.23.22 | 0.449 | |
| 1ez0 | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.449 | |
| 1h72 | ANP | Homoserine kinase | 2.7.1.39 | 0.449 | |
| 1ja0 | NAP | NADPH--cytochrome P450 reductase | / | 0.449 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.449 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 1od1 | 0QS | Endothiapepsin | 3.4.23.22 | 0.449 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.449 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.449 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.449 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.449 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.449 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.449 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.449 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.449 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.449 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.449 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.449 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.449 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3u78 | E67 | Lysine-specific demethylase 7A | 1.14.11 | 0.449 | |
| 4cng | SAH | SpoU rRNA methylase | / | 0.449 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.449 | |
| 4g3p | UD1 | Bifunctional protein GlmU | / | 0.449 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.449 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.449 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.449 | |
| 4ttc | FMN | Iodotyrosine deiodinase 1 | / | 0.449 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.449 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.449 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.448 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.448 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.448 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.448 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.448 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.448 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.448 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.448 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.448 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.448 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.448 | |
| 2oz0 | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.448 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.448 | |
| 2q0k | NAP | Thioredoxin reductase | 1.8.1.9 | 0.448 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.448 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.448 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.448 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.448 | |
| 3b5i | SAH | Indole-3-acetate O-methyltransferase 1 | / | 0.448 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3dz7 | O8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.448 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.448 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 3n14 | FMN | Xenobiotic reductase | / | 0.448 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.448 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.448 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.448 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.448 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.448 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.448 | |
| 1e2n | RCA | Thymidine kinase | / | 0.447 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1i5e | U5P | Uracil phosphoribosyltransferase | / | 0.447 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.447 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.447 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.447 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.447 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.447 | |
| 1xh6 | R94 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.447 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.447 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.447 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.447 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.447 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.447 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.447 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.447 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.447 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.447 | |
| 3gu3 | SAH | Methyltransferase | / | 0.447 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.447 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.447 | |
| 3kt8 | LTN | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.447 | |
| 3mtw | M3R | Xaa-Pro dipeptidase, putative | / | 0.447 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.447 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.447 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4ivb | 1J5 | Tyrosine-protein kinase JAK1 | / | 0.447 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.447 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.447 | |
| 4riy | ANP | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.447 | |
| 5k7u | SAM | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.447 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 1gox | FMN | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.446 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.446 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.446 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.446 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.446 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 2f3f | AXF | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2g94 | ZPQ | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.446 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.446 | |
| 3iu8 | T03 | Methionine aminopeptidase 2 | / | 0.446 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.446 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.446 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.446 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.446 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.446 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.446 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.446 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 4kqr | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.446 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 4pgh | SAM | Caffeic acid O-methyltransferase | / | 0.446 | |
| 4rje | FNR | Lactate oxidase | / | 0.446 | |
| 4rwn | APC | 2'-5'-oligoadenylate synthase 1 | 2.7.7.84 | 0.446 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.446 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.446 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.445 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.445 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1udc | UFM | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 1vza | UMP | Thymidylate synthase | / | 0.445 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.445 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.445 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.445 | |
| 2gr2 | APR | Ferredoxin reductase | / | 0.445 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.445 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2xfj | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.445 | |
| 2zr9 | DTP | Protein RecA | / | 0.445 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.445 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.445 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.445 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.445 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.445 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.445 | |
| 3vet | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.445 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.445 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.445 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.445 | |
| 4e2x | TYD | Methyltransferase | / | 0.445 | |
| 4js1 | CTN | Beta-galactoside alpha-2,6-sialyltransferase 1 | 2.4.99.1 | 0.445 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.445 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.445 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.445 | |
| 5bqf | NAP | Probable hydroxyacid dehydrogenase protein | / | 0.445 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.445 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.444 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.444 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.444 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.444 | |
| 2d81 | RB3 | Poly(3-hydroxybutyrate) depolymerase | / | 0.444 | |
| 2dxv | SAH | Diphthine synthase | / | 0.444 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2q0u | LAB | Actin, alpha skeletal muscle | / | 0.444 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.444 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.444 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.444 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.444 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.444 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3pld | F90 | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.444 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.444 | |
| 4cea | ZSW | Integrase | / | 0.444 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.444 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 4uoc | NCN | CinA-like protein | / | 0.444 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4y4j | LNR | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.444 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 5ebu | FMN | Lactate oxidase | / | 0.444 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.444 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.443 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.443 | |
| 1ds7 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.443 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.443 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.443 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.443 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.443 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1zap | A70 | Candidapepsin-2 | 3.4.23.24 | 0.443 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.443 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.443 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.443 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.443 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.443 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 2v00 | V15 | Endothiapepsin | 3.4.23.22 | 0.443 | |
| 3beo | UD1 | UDP-N-acetylglucosamine 2-epimerase | / | 0.443 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.443 | |
| 3ggj | 25H | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.443 | |
| 3hf3 | FMN | Chromate reductase | / | 0.443 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3ohf | 3HF | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.443 | |
| 3pch | CHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.443 | |
| 3qw8 | CYS_ARG_GLY_CYS_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.443 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.443 | |
| 3rk1 | ATP | N-type ATP pyrophosphatase superfamily | / | 0.443 | |
| 3sfu | RBV | Polyprotein | / | 0.443 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.443 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.443 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.443 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.443 | |
| 4e03 | ADP | Plasmid partitioning protein ParF | / | 0.443 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.443 | |
| 4lz8 | 1YX | Glutamate receptor 2 | / | 0.443 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.443 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.443 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.442 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.442 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.442 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.442 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.442 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.442 | |
| 1mrw | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.442 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.442 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 1xgi | NST | Beta-lactamase | 3.5.2.6 | 0.442 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.442 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.442 | |
| 2hch | N5A | Endoplasmin | / | 0.442 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2yvl | SAM | tRNA (adenine(58)-N(1))-methyltransferase TrmI | / | 0.442 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.442 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.442 | |
| 3bj8 | COA | Diamine acetyltransferase 1 | / | 0.442 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.442 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.442 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.442 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.442 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.442 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.442 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.442 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.442 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4fpy | 0V8 | Sialidase B | 3.2.1.18 | 0.442 | |
| 4fzb | 0VJ | Probable flavin-dependent thymidylate synthase | 2.1.1.148 | 0.442 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4kh0 | ATP | Aspartate carbamoyltransferase regulatory chain {ECO:0000256|HAMAP-Rule:MF_00002} | / | 0.442 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.442 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.442 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1dfo | PLG | Serine hydroxymethyltransferase | 2.1.2.1 | 0.441 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.441 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.441 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1qcw | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.441 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.441 | |
| 1tsx | UMP | Thymidylate synthase | / | 0.441 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.441 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2bun | FAD | AppA protein | / | 0.441 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.441 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.441 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.441 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.441 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.441 | |
| 2y88 | 2ER | Phosphoribosyl isomerase A | 5.3.1.16 | 0.441 | |
| 3afh | GSU | Glutamate--tRNA ligase 2 | / | 0.441 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.441 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
| 3l9h | EMQ | Kinesin-like protein KIF11 | / | 0.441 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.441 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.441 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.441 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.441 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4id9 | NAD | Putative UDP-glucose 4-epimerase | / | 0.441 | |
| 4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.441 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.441 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.441 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.441 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.441 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.441 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 1got | GDP | Guanine nucleotide-binding protein G(t) subunit alpha-1 | / | 0.440 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.440 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.440 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.440 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.440 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.440 | |
| 1swt | BTN | Streptavidin | / | 0.440 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.440 | |
| 2b8t | THM | Thymidine kinase | / | 0.440 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.440 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.440 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.440 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.440 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.440 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3e8x | NAP | BH1520 protein | / | 0.440 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.440 | |
| 3liv | E16 | Protease | / | 0.440 | |
| 3lq4 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3pmu | F7L | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 3ppo | DCK | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.440 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.440 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.440 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.440 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.440 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4cgj | NZL | Integrase | / | 0.440 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.440 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4kov | KOV | Uncharacterized protein | / | 0.440 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.440 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.440 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4y38 | 0A9 | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 4y3r | F06 | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.440 | |
| 5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.440 |