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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ju8TZDBenzoylformate decarboxylase4.1.1.7

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4ju8TZDBenzoylformate decarboxylase4.1.1.71.000
5dgtTZDBenzoylformate decarboxylase4.1.1.70.873
2fwnTDPBenzoylformate decarboxylase4.1.1.70.783
1bfdTPPBenzoylformate decarboxylase4.1.1.70.770
4qelTZDBenzoylformate decarboxylase4.1.1.70.752
4ju9TZDBenzoylformate decarboxylase4.1.1.70.747
4mq5TPPBenzoylformate decarboxylase4.1.1.70.746
1po7TZDBenzoylformate decarboxylase4.1.1.70.708
4mprTPPBenzoylformate decarboxylase4.1.1.70.688
4k9oTPPBenzoylformate decarboxylase4.1.1.70.649
4k9nTZDBenzoylformate decarboxylase4.1.1.70.648
4mzxTZDBenzoylformate decarboxylase4.1.1.70.639
3fznD7KBenzoylformate decarboxylase4.1.1.70.638
4mppTZDBenzoylformate decarboxylase4.1.1.70.636
4gm4TZDBenzoylformate decarboxylase4.1.1.70.632
4jucTPPBenzoylformate decarboxylase4.1.1.70.625
4jd5TZDBenzoylformate decarboxylase4.1.1.70.624
4jubTPPBenzoylformate decarboxylase4.1.1.70.623
4k9pTPPBenzoylformate decarboxylase4.1.1.70.611
4jufTPPBenzoylformate decarboxylase4.1.1.70.610
1mczTDPBenzoylformate decarboxylase4.1.1.70.609
4gm0TZDBenzoylformate decarboxylase4.1.1.70.601
4gg1TZDBenzoylformate decarboxylase4.1.1.70.572
4gm1TZDBenzoylformate decarboxylase4.1.1.70.539
2v3wTPPBenzoylformate decarboxylase4.1.1.70.530
3nxxNDPDihydrofolate reductase1.5.1.30.524
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.518
3ieuGDPGTPase Era/0.514
3fhyATPPyridoxal kinase2.7.1.350.513
4bfxZVXPantothenate kinase2.7.1.330.511
2yxuATPPyridoxal kinase2.7.1.350.510
5a3cNADSIR2 family protein/0.510
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.506
2givACOHistone acetyltransferase KAT8/0.502
3hyoADPPyridoxal kinase/0.501
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.501
1w5sADPORC1-type DNA replication protein 2/0.499
1bdbNADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase/0.498
3fql79ZGenome polyprotein2.7.7.480.498
4h12SAHHistone-lysine N-methyltransferase SETD22.1.1.430.498
3keuATPPyridoxal kinase2.7.1.350.497
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.497
2zdyADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.496
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.495
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.493
4la1FADThioredoxin glutathione reductase/0.493
2ou2ACOHistone acetyltransferase KAT5/0.492
4h1vGNPDynamin-1-like protein3.6.5.50.492
1iy8NADLevodione reductase/0.491
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.490
2ebaFADPutative glutaryl-CoA dehydrogenase/0.490
2y05NAPProstaglandin reductase 1/0.490
3p8z36AGenome polyprotein2.1.1.560.490
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.490
4i521HA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.490
2rc3NADCBS domain/0.489
2vhxNADAlanine dehydrogenase1.4.1.10.489
4irnFADAnaB/0.489
4e03ADPPlasmid partitioning protein ParF/0.488
4uugPXGBranched-chain amino acid aminotransferase, putative/0.488
5ig2NADShort-chain dehydrogenase/reductase SDR/0.488
3x2wATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.487
1lf3EH5Plasmepsin-23.4.23.390.486
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.486
2gv8NDPThiol-specific monooxygenase1.14.130.486
5c3aURMHisto-blood group ABO system transferase/0.486
4ctkSAMGenome polyprotein/0.485
5dbfNDPIridoid synthase1.3.1.990.485
1vsoAT1Glutamate receptor ionotropic, kainate 1/0.484
2qbuSAHPrecorrin-2 methyltransferase/0.484
2xlrFADPutative flavin-containing monooxygenase/0.484
3jzdNADMaleylacetate reductase/0.484
4fizCUE17beta-hydroxysteroid dehydrogenase/0.484
5emhNAPIridoid synthase1.3.1.990.484
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.484
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.483
2geuCOKPantothenate kinase2.7.1.330.483
1i5cADPChemotaxis protein CheA2.7.13.30.482
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.482
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.482
2pswCOAN-alpha-acetyltransferase 50/0.481
3c3eGDP2-phospho-L-lactate transferase/0.481
3mkhFADNitroalkane oxidase/0.481
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.481
2jih097A disintegrin and metalloproteinase with thrombospondin motifs 13.4.240.480
2pg0FADAcyl-CoA dehydrogenase/0.480
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.480
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.480
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.480
4ctjSAMGenome polyprotein/0.480
4o1mNADEnoyl-acyl carrier reductase/0.480
1h6dNDPGlucose--fructose oxidoreductase1.1.99.280.479
1mj9COAHistone acetyltransferase ESA1/0.479
2bjfDXCCholoylglycine hydrolase3.5.1.240.479
3dh9FADThioredoxin reductase 1, mitochondrial1.8.1.90.479
3eksCY9Actin-5C/0.479
3t2zFADSulfide-quinone reductase/0.479
4fse0VABeta-secretase 13.4.23.460.479
5dbgNADIridoid synthase1.3.1.990.479
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.479
1fduNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.478
1g8jMGDArsenite oxidase subunit AioA1.20.9.10.478
1jqiFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.478
3elySAHMethyltransferase/0.478
3kpkFADSulfide-quinone reductase/0.478
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.478
5jscFADPutative acyl-CoA dehydrogenase/0.478
1edoNAP3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic1.1.1.1000.477
1u7hNADPutative ornithine cyclodeaminase/0.477
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.477
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.477
2igyA2TPlasmepsin 2/0.477
2cduFADNADH oxidase/0.476
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.476
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3imgBZ2Pantothenate synthetase6.3.2.10.476
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.476
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.476
4bftZVTPantothenate kinase2.7.1.330.476
1ofgNDPGlucose--fructose oxidoreductase1.1.99.280.474
1sdwIYTPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.474
3evcSAHGenome polyprotein2.1.1.560.474
3gqvNAPEnoyl reductase LovC10.474
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.474
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.474
4b4w9L9Bifunctional protein FolD/0.474
4djaFAD(6-4) photolyase/0.474
4yaiNAIC alpha-dehydrogenase/0.474
5jydNADShort chain dehydrogenase/0.474
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.473
1mjaCOAHistone acetyltransferase ESA1/0.473
1pl1ABYGlutathione S-transferase A12.5.1.180.473
1tysDHFThymidylate synthase/0.473
1xddAAYIntegrin alpha-L/0.473
2fonFADAcyl-coenzyme A oxidase/0.473
2g76NADD-3-phosphoglycerate dehydrogenase1.1.1.950.473
3pxvFMNNitroreductase/0.473
3tog079Gag-Pol polyprotein2.7.7.490.473
4j7uNAPSepiapterin reductase1.1.1.1530.473
1vdcFADThioredoxin reductase 1, mitochondrial1.8.1.90.472
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.472
2gesCOKPantothenate kinase2.7.1.330.472
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.472
2vijC44Beta-secretase 13.4.23.460.472
2yvfNADFerredoxin reductase/0.472
2zfnACOHistone acetyltransferase RTT1092.3.1.480.472
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.472
3h86AP5Adenylate kinase/0.472
3q43D66M1 family aminopeptidase3.4.110.472
4fhf0TTSpore photoproduct lyase/0.472
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.472
4nesUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.472
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.471
1rwbNADGlucose 1-dehydrogenase1.1.1.470.471
1x7gNAPPutative ketoacyl reductase1.3.10.471
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.471
3d3wNAPL-xylulose reductase1.1.1.100.471
3toh079Gag-Pol polyprotein2.7.7.490.471
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
4h4uFADBiphenyl dioxygenase ferredoxin reductase subunit/0.471
5dldUD1UDP-N-Acetylglucosamine 2-epimerase/0.471
1typFADTrypanothione reductase1.8.1.120.470
2ctsCOACitrate synthase, mitochondrial2.3.3.10.470
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.470
2qjoNADBifunctional NMN adenylyltransferase/Nudix hydrolase2.7.7.10.470
2vj6VG5Beta-secretase 13.4.23.460.470
2wksCB63-dehydroquinate dehydratase4.2.1.100.470
3c8bARG_ARG_GLY_ILE_NH2Botulinum neurotoxin type A3.4.24.690.470
3eldSFGMethyltransferase/0.470
3umsGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.470
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.470
4uymVOR14-alpha sterol demethylase Cyp51B/0.470
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.470
1tehNADAlcohol dehydrogenase class-31.1.1.10.469
2p83MR0Beta-secretase 13.4.23.460.469
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.469
2yutNAPPutative short-chain oxidoreductase/0.469
2zjmF1MBeta-secretase 13.4.23.460.469
3a37ADPATPase GET3/0.469
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.469
3s55NADPutative short-chain dehydrogenase/reductase/0.469
4eiqKCTPutative FAD-monooxygenase/0.469
1geeNADGlucose 1-dehydrogenase1.1.1.470.468
1ryeNDPGlucose--fructose oxidoreductase1.1.99.280.468
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.468
2npaMMBPeroxisome proliferator-activated receptor alpha/0.468
2zr9DTPProtein RecA/0.468
3ekuCY9Actin-5C/0.468
3jvvACPTwitching mobility protein/0.468
3phiNDPShikimate dehydrogenase (NADP(+))/0.468
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.468
3uylTYDProbable NDP-rhamnosyltransferase/0.468
4gah0ETAcyl-coenzyme A thioesterase THEM43.1.2.20.468
4tlzFADKtzI/0.468
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.467
1w5tANPORC1-type DNA replication protein 2/0.467
1yqzCOACoenzyme A disulfide reductase/0.467
2d0oADPDiol dehydratase-reactivating factor alpha subunit/0.467
2gr1FADFerredoxin reductase/0.467
2v6gNAP3-oxo-Delta(4,5)-steroid 5-beta-reductase/0.467
2znnS44Peroxisome proliferator-activated receptor alpha/0.467
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.467
3ivgFG5Pantothenate synthetase6.3.2.10.467
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.467
3uozNAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.467
4ambDUDPutative glycosyl transferase/0.467
4kqwNAPKetol-acid reductoisomerase (NADP(+))/0.467
5i39FADL-amino acid deaminase/0.467
1w48APCNTPase P4/0.466
1z7yAA5Cysteine synthase 12.5.1.470.466
2d1cNAPIsocitrate dehydrogenase [NADP]1.1.1.420.466
3f90FMNFlavodoxin/0.466
3i0pNADMalate dehydrogenase, putative/0.466
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.466
3o7lANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.466
4dplNAPMalonyl-CoA reductase1.2.1.750.466
5a3bAPRSIR2 family protein/0.466
5ahsFADAcyl-CoA dehydrogenase/0.466
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.465
2nnhREACytochrome P450 2C8/0.465
3b70NAPEnoyl reductase LovC10.465
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.465
3dszLIZNeutrophil gelatinase-associated lipocalin/0.465
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.465
3nsh957Beta-secretase 13.4.23.460.465
3sz0FADSulfide-quinone reductase/0.465
3t14FADSulfide-quinone reductase/0.465
4i0i957Beta-secretase 13.4.23.460.465
4i6gFADCryptochrome-2/0.465
1fy7COAHistone acetyltransferase ESA1/0.464
1n75ATPGlutamate--tRNA ligase6.1.1.170.464
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.464
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.464
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.464
2y0mACOHistone acetyltransferase KAT8/0.464
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
3dmeFADPutative conserved exported protein/0.464
3gegNADShort-chain dehydrogenase/reductase SDR/0.464
3ha5SFGHydroxymycolate synthase MmaA42.1.10.464
3pfdFDAAcyl-CoA dehydrogenase FadE25/0.464
4fvqATPTyrosine-protein kinase JAK2/0.464
4g7gVFVLanosterol 14-alpha-demethylase/0.464
4hwkNAPSepiapterin reductase1.1.1.1530.464
4mihFADPyranose 2-oxidase1.1.3.100.464
1f20NAPNitric oxide synthase, brain1.14.13.390.463
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.463
1qrpHH0Pepsin A-43.4.23.10.463
2cbrA80Cellular retinoic acid-binding protein 1/0.463
2ez9TDKPyruvate oxidase1.2.3.30.463
2ozuACOHistone acetyltransferase KAT6A/0.463
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.463
2rhqGAXPhenylalanine--tRNA ligase alpha subunit/0.463
2vhvNAIAlanine dehydrogenase1.4.1.10.463
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
3eofFMNPutative oxidase/0.463
3iocA5DPantothenate synthetase6.3.2.10.463
3oq6PFBAlcohol dehydrogenase E chain1.1.1.10.463
3t7x4SHEndothiapepsin3.4.23.220.463
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.463
4frkDWDBeta-secretase 13.4.23.460.463
4qedNAPElxO/0.463
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.462
1kh2ATPArgininosuccinate synthase/0.462
1krrACOGalactoside O-acetyltransferase2.3.1.180.462
1kt6RTLRetinol-binding protein 4/0.462
1me6IVSPlasmepsin-23.4.23.390.462
1w6hTITPlasmepsin-23.4.23.390.462
1zk7FADMercuric reductase1.16.1.10.462
2cnsACORibosomal-protein-alanine acetyltransferase/0.462
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.462
2fznFADBifunctional protein PutA1.5.5.20.462
2j83BATUlilysin3.4.240.462
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.462
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.462
2zu8GDDMannosyl-3-phosphoglycerate synthase2.4.1.2170.462
3bg7FADPyranose 2-oxidase/0.462
3ivxFG6Pantothenate synthetase6.3.2.10.462
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.462
3nl6ACPUncharacterized protein/0.462
3uj7SAMPhosphoethanolamine N-methyltransferase/0.462
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.462
4dfg0JVGag-Pol polyprotein3.4.23.160.462
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.462
4i4z2NE1,4-dihydroxy-2-naphthoyl-CoA synthase/0.462
4kx6FADFumarate reductase flavoprotein subunit1.3.5.40.462
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.462
5irnADPNucleotide binding oligomerization domain containing 2/0.462
1e94ANPATP-dependent protease ATPase subunit HslU/0.461
1odcA8BAcetylcholinesterase3.1.1.70.461
1x7dNADPutative ornithine cyclodeaminase/0.461
1zdwFLVPrenyltransferase/0.461
2il2LIXRenin3.4.23.150.461
3fpzAHZThiamine thiazole synthase/0.461
3mx5UTPNucleoprotein/0.461
3p8zSAHGenome polyprotein2.1.1.560.461
3qrwNDPPutative ketoacyl reductase1.3.10.461
3ut5LOCTubulin beta chain/0.461
3zl8ADPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.461
4a83DXCMajor pollen allergen Bet v 1-A/0.461
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.461
4fsl0VBBeta-secretase 13.4.23.460.461
4i09CMPcAMP-activated global transcriptional regulator CRP/0.461
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.461
4qe6JN3Bile acid receptor/0.461
5koiNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.461
1rydNDPGlucose--fructose oxidoreductase1.1.99.280.460
1szfFMNCytochrome b2, mitochondrial1.1.2.30.460
1youPFDCollagenase 33.4.240.460
2bfoNDPPteridine reductase 11.5.1.330.460
2g1n1IGRenin3.4.23.150.460
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.460
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.460
2lfoGCHFatty acid-binding protein, liver/0.460
2vhwNAIAlanine dehydrogenase1.4.1.10.460
2ym2FADPhenylacetone monooxygenase1.14.13.920.460
3b6zCO7Enoyl reductase LovC10.460
3m9vTYDFAD-dependent oxidoreductase/0.460
3owaFADAcyl-CoA dehydrogenase/0.460
3q44D50M1 family aminopeptidase3.4.110.460
3to6LYS_CMCHistone acetyltransferase ESA1/0.460
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.460
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.460
4g3jVNTLanosterol 14-alpha-demethylase/0.460
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.460
4qaiFMNNADPH dehydrogenase/0.460
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.460
5br4NADLactaldehyde reductase1.1.1.770.460
1a5bIGPTryptophan synthase alpha chain/0.459
1gnwGTXGlutathione S-transferase F22.5.1.180.459
1tysTMPThymidylate synthase/0.459
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.459
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.459
2plwSAMRibosomal RNA methyltransferase, putative/0.459
2po7CHDFerrochelatase, mitochondrial4.99.1.10.459
2viyVG3Beta-secretase 13.4.23.460.459
2zrfDTPProtein RecA/0.459
3cscACOCitrate synthase, mitochondrial2.3.3.10.459
3gbuATPUncharacterized sugar kinase PH14592.7.10.459
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.459
3icpNADNAD-dependent epimerase/dehydratase/0.459
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.459
3wqmB29Diterpene synthase3.1.7.80.459
3zhtTD9Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.459
4b79NADProbable short-chain dehydrogenase/0.459
4i421HA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.459
4opuFDAConserved Archaeal protein/0.459
1f0xFADD-lactate dehydrogenase1.1.1.280.458
1fecFADTrypanothione reductase1.8.1.120.458
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1yb5NAPQuinone oxidoreductase1.6.5.50.458
2aa0MTPAdenosine kinase2.7.1.200.458
2ahrNAPPyrroline-5-carboxylate reductase/0.458
2cntCOARibosomal-protein-alanine acetyltransferase/0.458
2dteNAIGlucose 1-dehydrogenase related protein/0.458
2xlpFADPutative flavin-containing monooxygenase/0.458
3d91REMRenin3.4.23.150.458
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.458
3ibdCPZCytochrome P450 2B61.14.130.458
3kb1ADPIron-sulfur cluster carrier protein/0.458
3l0lHC3Nuclear receptor ROR-gamma/0.458
3lpkZ76Beta-secretase 13.4.23.460.458
3qgf46FGenome polyprotein2.7.7.480.458
3r3sNADPutative oxidoreductase/0.458
3t88S0N1,4-dihydroxy-2-naphthoyl-CoA synthase/0.458
3u4cNDPNADPH-dependent reductase BacG/0.458
3v0o4GWHisto-blood group ABO system transferase/0.458
3vydVYDRenin3.4.23.150.458
4b722FBBeta-secretase 13.4.23.460.458
4biwANPSensor histidine kinase CpxA/0.458
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.458
4q71FADBifunctional protein PutA/0.458
4y3zF41Endothiapepsin3.4.23.220.458
4yagNAIC alpha-dehydrogenase/0.458
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.458
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.457
1fwkADPHomoserine kinase2.7.1.390.457
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.457
1o86LPRAngiotensin-converting enzyme3.2.10.457
1oaaNAPSepiapterin reductase1.1.1.1530.457
1tj0FADBifunctional protein PutA1.5.5.20.457
1y0s331Peroxisome proliferator-activated receptor delta/0.457
1zgbA1EAcetylcholinesterase3.1.1.70.457
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3bnkFMNFlavoredoxin/0.457
3kybFADUDP-galactopyranose mutase5.4.99.90.457
3nixFADFlavoprotein/dehydrogenase/0.457
3toxNAPPutative oxidoreductase/0.457
3tr05GPGuanylate kinase/0.457
3v76FDAUncharacterized protein/0.457
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
4b0j3MQ3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase4.2.1.590.457
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.457
4ddyDN6Beta-lactamase/0.457
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.457
4fn4NADShort chain dehydrogenase/0.457
4prvADPDNA gyrase subunit B/0.457
4v37NADBetaine aldehyde dehydrogenase, chloroplastic1.2.1.80.457
1gsnFADGlutathione reductase, mitochondrial1.8.1.70.456
1mjbACOHistone acetyltransferase ESA1/0.456
1osvCHCBile acid receptor/0.456
1poxTPPPyruvate oxidase1.2.3.30.456
1pq944BOxysterols receptor LXR-beta/0.456
1vcfFMNIsopentenyl-diphosphate delta-isomerase/0.456
2aviBTNAvidin/0.456
2e0aANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.456
2fdpFRPBeta-secretase 13.4.23.460.456
2g8yNADHydroxycarboxylate dehydrogenase B/0.456
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2wa2SAMGenome polyprotein/0.456
3a3gDLZLumazine protein/0.456
3g7jGTXGlutathione transferase GST1-4/0.456
3jszUPGUncharacterized protein/0.456
3r7kFDAProbable acyl CoA dehydrogenase/0.456
3wagTYDGlycosyltransferase/0.456
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.456
4nxxGDPMitochondrial dynamics protein MID51/0.456
4s26SAHPhosphomethylpyrimidine synthase, chloroplastic4.1.99.170.456
4xybNDPFormate dehydrogenase/0.456
4z24FADPutative GMC-type oxidoreductase R13510.456
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.456
5dmhADP3-oxo-tetronate kinase/0.456
1g9rUPFLgtC/0.455
1geuFADGlutathione reductase1.8.1.70.455
1k7l544Peroxisome proliferator-activated receptor alpha/0.455
1kvuUPGUDP-glucose 4-epimerase5.1.3.20.455
1l0oADPAnti-sigma F factor/0.455
1ppm0P1Penicillopepsin-13.4.23.200.455
1u65CP0Acetylcholinesterase3.1.1.70.455
1x1cSAHC-20 methyltransferase/0.455
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2q4wFADCytokinin dehydrogenase 71.5.99.120.455
2webPP4Penicillopepsin-13.4.23.200.455
2z1qFADAcyl-CoA dehydrogenase/0.455
2z6iFMN2-nitropropane dioxygenase/0.455
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.455
2zb3NDPProstaglandin reductase 21.3.1.480.455
3rpeFADPutative modulator of drug activity/0.455
3sh0SAXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.455
3tfyCOAN-alpha-acetyltransferase 502.3.10.455
3uj8SFGPhosphoethanolamine N-methyltransferase/0.455
3vsxR32Renin3.4.23.150.455
4a2aATPCell division protein FtsA/0.455
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.455
4dc0NDPPutative ketoacyl reductase1.3.10.455
4dh60KNBeta-secretase 13.4.23.460.455
4exg916Beta-secretase 13.4.23.460.455
4k6mSAHGenome polyprotein/0.455
4mwzSAMPhosphoethanolamine N-methyltransferase, putative/0.455
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.455
4qxr1YEStimulator of interferon genes protein/0.455
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
5droZH2UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.455
1bxqPP8Penicillopepsin-13.4.23.200.454
1e81M91Endothiapepsin3.4.23.220.454
1e82M90Endothiapepsin3.4.23.220.454
1gotGDPGuanine nucleotide-binding protein G(t) subunit alpha-1/0.454
1in5ADPHolliday junction ATP-dependent DNA helicase RuvB/0.454
1nffNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.454
1p4mADPRiboflavin kinase2.7.1.260.454
1z7eUGABifunctional polymyxin resistance protein ArnA/0.454
2ilvC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.454
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.454
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.454
2q4bNAPUncharacterized protein At5g02240/0.454
2ycnP61Tyrosine phenol-lyase4.1.99.20.454
2ylzFADPhenylacetone monooxygenase1.14.13.920.454
2ym1FADPhenylacetone monooxygenase1.14.13.920.454
3lshFADPyranose 2-oxidase/0.454
3lsiFADPyranose 2-oxidase/0.454
3lsmSFDPyranose 2-oxidase/0.454
3qwbNDPProbable quinone oxidoreductase1.6.5.50.454
3sx2NADUncharacterized protein/0.454
3zcsCAWGlycogen phosphorylase, muscle form2.4.1.10.454
4d5gFADCyclohexane-1,2-dione hydrolase3.7.1.110.454
4fkzUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.454
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.454
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
4iv6FDAIsovaleryl-CoA dehydrogenase/0.454
4oztP1AEcdysone receptor, putative/0.454
4qi5FADCellobiose dehydrogenase/0.454
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.454
4tm1FDAKtzI/0.454
4wjiNAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase/0.454
4wluNADMalate dehydrogenase, mitochondrial1.1.1.370.454
1n2hPAJPantothenate synthetase6.3.2.10.453
1p0hCOAMycothiol acetyltransferase2.3.1.1890.453
1ppjANYCytochrome b/0.453
1qyvNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.453
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2dftADPShikimate kinase2.7.1.710.453
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.453
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2zevB71Geranylgeranyl pyrophosphate synthase/0.453
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.453
3h06VBPGlutamate receptor 2/0.453
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.453
3nd6ATPPhosphopantetheine adenylyltransferase/0.453
3pi0F91Endothiapepsin3.4.23.220.453
3qlsNDPDihydrofolate reductase1.5.1.30.453
3sxjSAMPutative methyltransferase/0.453
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4h1q0XXMatrix metalloproteinase-93.4.24.350.453
4hl1ZZ7Metallo-beta-lactamase type 2/0.453
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.453
4jldADPAdenylate kinase/0.453
4nbwNADShort-chain dehydrogenase/reductase SDR/0.453
4xj3GTPCyclic GMP-AMP synthase/0.453
4xqcNADHomospermidine synthase2.5.1.440.453
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.453
5ckuFADL-ornithine N(5)-monooxygenase/0.453
5ez7FADProbable FAD-dependent oxidoreductase PA4991/0.453
1g63FMNEpidermin decarboxylase4.1.10.452
1juvNDPDihydrofolate reductase1.5.1.30.452
1nvmNADAcetaldehyde dehydrogenase1.2.1.100.452
1ot7CHCBile acid receptor/0.452
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.452
1xq6NAPUncharacterized protein At5g02240/0.452
2bl4NADLactaldehyde reductase1.1.1.770.452
2draATPCCA-adding enzyme2.7.7.720.452
2eq9FADDihydrolipoyl dehydrogenase/0.452
2ft9CHDFatty acid-binding protein 2, liver/0.452
2g1r3IGRenin3.4.23.150.452
2h12CMXCitrate synthase/0.452
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.452
2r26CMCCitrate synthase2.3.3.160.452
2rgjFADFlavin-containing monooxygenase/0.452
2wp9CBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.452
2wp9CBESuccinate dehydrogenase cytochrome b556 subunit/0.452
3f63GTXGlutathione transferase GST1-4/0.452
3ixj586Beta-secretase 13.4.23.460.452
3otwCOAPhosphopantetheine adenylyltransferase/0.452
3p4tFAOPutative acyl-CoA dehydrogenase/0.452
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.452
3uleC69Actin-related protein 3/0.452
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.452
4g5qGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.452
4kugNAD3-hydroxybutyryl-CoA dehydrogenase/0.452
4obwSAM2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial/0.452
4tvbNADHomospermidine synthase2.5.1.440.452
4xguADPPutative pachytene checkpoint protein 2/0.452
1booSAHModification methylase PvuII2.1.1.1130.451
1g1aNADdTDP-glucose 4,6-dehydratase/0.451
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.451
1rdwLARActin, alpha skeletal muscle/0.451
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.451
1v35NAIEnoyl-ACP reductase/0.451
1x1dSAHC-20 methyltransferase/0.451
1xe55FEPlasmepsin-23.4.23.390.451
2c0cNAPProstaglandin reductase 310.451
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.451
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2hfpNSIPeroxisome proliferator-activated receptor gamma/0.451
2oz57XYUncharacterized protein/0.451
2p41SAHGenome polyprotein/0.451
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.451
2tpsTPSThiamine-phosphate synthase/0.451
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.451
3f3sNADLambda-crystallin homolog/0.451
3ge6FMNNitroreductase/0.451
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.451
3k4nFADPyranose 2-oxidase/0.451
3kpbSAMUncharacterized protein MJ0100/0.451
3r96ACOMccE protein/0.451
4epq0RRPoly(ADP-ribose) glycohydrolase/0.451
4eqsCOACoenzyme A disulfide reductase/0.451
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4h4wFADBiphenyl dioxygenase ferredoxin reductase subunit/0.451
4h6rFDAProline dehydrogenase/0.451
4j7xNAPSepiapterin reductase1.1.1.1530.451
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.451
4pzsACOHistone acetyltransferase p300/0.451
4q73FADBifunctional protein PutA/0.451
4x28FDAAcyl-CoA dehydrogenase FadE26/0.451
4x28FDAAcyl-CoA dehydrogenase FadE27/0.451
5idwNAPShort-chain dehydrogenase/reductase SDR/0.451
1bzlFADTrypanothione reductase1.8.1.120.450
1cg4IMOAdenylosuccinate synthetase/0.450
1kp3ATPArgininosuccinate synthase6.3.4.50.450
1nzfUPGDNA beta-glucosyltransferase/0.450
1pfyMSPMethionine--tRNA ligase6.1.1.100.450
2ed3SAHDiphthine synthase/0.450
2qa2FADPolyketide oxygenase CabE/0.450
2ql6ADPNicotinamide riboside kinase 1/0.450
2y3rTRKTamL/0.450
2yd0BESEndoplasmic reticulum aminopeptidase 13.4.110.450
2ykeYKEHeat shock protein HSP 90-alpha/0.450
3atyFMNProstaglandin F2a synthase/0.450
3cosNADAlcohol dehydrogenase 41.1.1.10.450
3iafTPPBenzaldehyde lyase/0.450
3iltTRUGlutamate receptor 2/0.450
3k4cFADPyranose 2-oxidase/0.450
3k5c0BIBeta-secretase 13.4.23.460.450
3ox4NADAlcohol dehydrogenase 21.1.1.10.450
3qfrFADNADPH--cytochrome P450 reductase/0.450
3sglFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC/0.450
3ua808WGlutamate receptor 2/0.450
4d89BXDBeta-secretase 13.4.23.460.450
4dpwAGSMevalonate diphosphate decarboxylase/0.450
4g67SAHUncharacterized ACR, COG1565 superfamily/0.450
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.450
4ikeADPAdenylate kinase/0.450
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.450
4jtqNAPAldo-keto reductase family 1 member C2/0.450
4z26FADPutative GMC-type oxidoreductase R13510.450
5ej9TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.450
1bk0ACVIsopenicillin N synthase1.21.3.10.449
1dljUGAUDP-glucose 6-dehydrogenase/0.449
1hb3SCVIsopenicillin N synthase1.21.3.10.449
1q51CAA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.449
1qorNDPQuinone oxidoreductase 1/0.449
1szgFNSCytochrome b2, mitochondrial1.1.2.30.449
2gjlFMNNitronate monooxygenase1.13.12.160.449
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2vtbFADCryptochrome DASH, chloroplastic/mitochondrial/0.449
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
3a0tADPSensor histidine kinase/0.449
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.449
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3ha7B32Hydroxymycolate synthase MmaA42.1.10.449
3rdqDTBStreptavidin/0.449
3rn8RN8Glutamate receptor 2/0.449
3tdj3TJGlutamate receptor 2/0.449
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.449
3w8eNAD3-hydroxybutyrate dehydrogenase/0.449
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.449
4blrUTPNTPase P4/0.449
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.449
4fcwADPChaperone protein ClpB/0.449
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.449
4m10ICDProstaglandin G/H synthase 21.14.99.10.449
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.449
5cfpC2EStimulator of interferon genes protein/0.449
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.449
1b2lNDCAlcohol dehydrogenase1.1.1.10.448
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.448
1jipKTN6-deoxyerythronolide B hydroxylase/0.448
1jr8FADFAD-linked sulfhydryl oxidase ERV21.8.3.20.448
1kevNDPNADP-dependent isopropanol dehydrogenase1.1.1.800.448
1knrFADL-aspartate oxidase1.4.3.160.448
1n2iPAJPantothenate synthetase6.3.2.10.448
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.448
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.448
1tqf32PBeta-secretase 13.4.23.460.448
1u4oNDDL-lactate dehydrogenase1.1.1.270.448
1x7hNDPPutative ketoacyl reductase1.3.10.448
1zh8NAPUncharacterized protein/0.448
2gciMRRProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.448
2gqfFADUncharacterized protein HI_0933/0.448
2p20PRXAcetyl-coenzyme A synthetase/0.448
2r0cFADPutative FAD-monooxygenase/0.448
2rcyNAPPyrroline-5-carboxylate reductase/0.448
2znpK55Peroxisome proliferator-activated receptor delta/0.448
3bgxMEFThymidylate synthase/0.448
3d8xFADThioredoxin reductase 11.8.1.90.448
3dk8FADGlutathione reductase, mitochondrial1.8.1.70.448
3mddFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.448
3o3pGDDGlycosyl transferase, family 2/0.448
3omuIBDHeat shock protein 83/0.448
3pm9FADPutative oxidoreductase/0.448
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.448
3uoxFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.448
3up5FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.448
4bfuZVUPantothenate kinase2.7.1.330.448
4bmsNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.448
4dvi2IWTankyrase-12.4.2.300.448
4egbNADdTDP-glucose 4,6-dehydratase/0.448
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.448
4iaoAPRNAD-dependent histone deacetylase SIR23.5.10.448
4mkhAP5Adenylate kinase/0.448
4nauAGSPhosphopantetheine adenylyltransferase/0.448
4wudANPDNA gyrase subunit B/0.448
4xgxADPFAD:protein FMN transferase/0.448
4yjdFADD-amino-acid oxidase1.4.3.30.448
5bw4SAMUncharacterized protein/0.448
5c1mCLRMu-type opioid receptor/0.448
5ch7MD1DMSO reductase family type II enzyme, molybdopterin subunit/0.448
5dg3U21Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase/0.448
1tj2FADBifunctional protein PutA1.5.5.20.447
1xkdNAPIsocitrate dehydrogenase [NADP]/0.447
1y3aGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.447
2aqbTL63-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.447
2dvlFADAcyl-CoA dehydrogenase/0.447
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.447
2v7a627Tyrosine-protein kinase ABL12.7.10.20.447
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
3ekp478Gag-Pol polyprotein3.4.23.160.447
3ix3OHNTranscriptional activator protein LasR/0.447
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.447
3q9tFAYUncharacterized protein/0.447
4cy8FDA2-hydroxybiphenyl-3-monooxygenase/0.447
4dpi0N1Beta-secretase 13.4.23.460.447
4fgrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.447
4i5cC5ITyrosine-protein kinase JAK1/0.447
4ipw1G7Mycocyclosin synthase1.14.21.90.447
4l4xNDPAmphI/0.447
4opgFDAConserved Archaeal protein/0.447
4xgiNADGlutamate dehydrogenase/0.447
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.447
5hg0SAMPantothenate synthetase/0.447
1daaPLPD-alanine aminotransferase2.6.1.210.446
1f8wFADNADH peroxidase1.11.1.10.446
1h6bNDPGlucose--fructose oxidoreductase1.1.99.280.446
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.446
1mrwK57Gag-Pol polyprotein3.4.23.160.446
1nytNAPShikimate dehydrogenase (NADP(+))/0.446
1o01NADAldehyde dehydrogenase, mitochondrial1.2.1.30.446
2c2aADPSensor histidine kinase/0.446
2dv4SAHDiphthine synthase/0.446
2fb2SAMGTP 3',8-cyclase4.1.99.180.446
2iqgF2IBeta-secretase 13.4.23.460.446
2r8oT5XTransketolase 1/0.446
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2vprTDCTetracycline repressor protein class H/0.446
2woa576Macrophage metalloelastase3.4.24.650.446
2yvlSAMtRNA (adenine(58)-N(1))-methyltransferase TrmI/0.446
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.446
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.446
3a28NADL-2,3-butanediol dehydrogenase1.1.1.760.446
3b8z294A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.446
3e92G6AMitogen-activated protein kinase 14/0.446
3fzfATPHeat shock cognate 71 kDa protein/0.446
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.446
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3kry3KRCollagenase 33.4.240.446
3qe2FMNNADPH--cytochrome P450 reductase/0.446
3vswR31Renin3.4.23.150.446
3wczNAPAldo-keto reductase AKR2E4/0.446
4gh5NADShort-chain dehydrogenase/reductase SDR/0.446
4u2tFADCholesterol oxidase1.1.3.60.446
4udqFAD5-(hydroxymethyl)furfural oxidase/0.446
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.446
4xq9NADHomospermidine synthase2.5.1.440.446
4yxm2BADNA integrity scanning protein DisA/0.446
5fl3ADPPili retraction protein PilT/0.446
1ae1NAPTropinone reductase 1/0.445
1af00Z9Serralysin3.4.24.400.445
1ef92CPMethylmalonyl-CoA decarboxylase4.1.1.410.445
1fm4DXCMajor pollen allergen Bet v 1-L/0.445
1g6oADPCag alpha/0.445
1mokFAD2-oxopropyl-CoM reductase, carboxylating1.8.1.50.445
2b3dFADModulator of drug activity B/0.445
2dsgSAHDiphthine synthase/0.445
2freFMNNAD(P)H-flavin oxidoreductase/0.445
2ignFADPyranose 2-oxidase/0.445
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.445
2xgs44PUncharacterized protein/0.445
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
2yr4FADPhenylalanine 2-monooxygenase precursor1.13.12.90.445
2yy5WSATryptophan--tRNA ligase6.1.1.20.445
3f6sFMNFlavodoxin/0.445
3ojwFMNNADPH--cytochrome P450 reductase/0.445
3pcrGTPADP-ribosylation factor 6/0.445
3q1kADPD-alanine--D-alanine ligase A6.3.2.40.445
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.445
3thrC2FGlycine N-methyltransferase2.1.1.200.445
3w8dNAD3-hydroxybutyrate dehydrogenase/0.445
4acxS8ZBeta-secretase 13.4.23.460.445
4dzzADPPlasmid partitioning protein ParF/0.445
4ey20RMMetallo-beta-lactamase type 2/0.445
4gt3ATPMitogen-activated protein kinase 12.7.11.240.445
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.445
4nieNBHNuclear receptor ROR-gamma/0.445
4o8aFADBifunctional protein PutA1.2.1.880.445
4qtuSAM18S rRNA (guanine(1575)-N(7))-methyltransferase/0.445
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
4xnhACON-terminal acetyltransferase A complex subunit NAT52.3.10.445
5cfn2BAStimulator of interferon genes protein/0.445
1cs4GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.444
1gerFADGlutathione reductase1.8.1.70.444
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.444
1la2NADInositol-3-phosphate synthase5.5.1.40.444
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.444
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.444
1sozVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.444
1uyhPU0Heat shock protein HSP 90-alpha/0.444
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.444
2g247IGRenin3.4.23.150.444
2idkC2FGlycine N-methyltransferase2.1.1.200.444
2iviACWIsopenicillin N synthase1.21.3.10.444
2vigCOSShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.444
3ajrNADNDP-sugar epimerase/0.444
3b1dPLSBetaC-S lyase/0.444
3bac3B9DNA ligase/0.444
3ishFADThioredoxin reductase1.8.1.90.444
3kr4BESM17 leucyl aminopeptidase/0.444
3pgxNADUncharacterized NAD-dependent oxidoreductase MAP_4146/0.444
3ukuC69Actin-related protein 3/0.444
3uoyNAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.444
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.444
4bb3KKAIsopenicillin N synthase1.21.3.10.444
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.444
4bfwZVWPantothenate kinase2.7.1.330.444
4eb5PLPCysteine desulfurase IscS 2/0.444
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.444
4klaCHDFerrochelatase, mitochondrial4.99.1.10.444
4rh10TTSpore photoproduct lyase/0.444
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.444
4y57F63Endothiapepsin3.4.23.220.444
4y9qC2EUncharacterized protein/0.444
4yntFDAGlucose oxidase, putative/0.444
5af7FADAcyl-CoA dehydrogenase/0.444
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.444
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.443
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
1hzjUD1UDP-glucose 4-epimerase/0.443
1obnASVIsopenicillin N synthase1.21.3.10.443
1pjkANPCasein kinase II subunit alpha2.7.11.10.443
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.443
1ri1GTGmRNA cap guanine-N7 methyltransferase2.1.1.560.443
1ut6A8NAcetylcholinesterase3.1.1.70.443
2b4rAESGlyceraldehyde-3-phosphate dehydrogenase/0.443
2c12FADNitroalkane oxidase1.7.3.10.443
2eq6FADDihydrolipoyl dehydrogenase/0.443
2g21L1BRenin3.4.23.150.443
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.443
2qcuFADAerobic glycerol-3-phosphate dehydrogenase1.1.5.30.443
2vhzNAIAlanine dehydrogenase1.4.1.10.443
2vnaNAPProstaglandin reductase 21.3.1.480.443
2wb2FADRE11660p/0.443
2z1mNDPGDP-mannose 4,6-dehydratase/0.443
3bi2FADPolyamine oxidase FMS1/0.443
3cib314Beta-secretase 13.4.23.460.443
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.443
3coy53HPantothenate synthetase6.3.2.10.443
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.443
3mo0SAHHistone-lysine N-methyltransferase EHMT1/0.443
3oqfS51Renin3.4.23.150.443
3q5lKX2Heat shock protein 83-1/0.443
3r9uFADThioredoxin reductase/0.443
3s1aATPCircadian clock protein kinase KaiC2.7.11.10.443
3sfeFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.443
3syiFADSulfide-quinone reductase/0.443
3tqcADPPantothenate kinase/0.443
3w8qAGSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.443
3w8rACPUridine kinase/0.443
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4gkvNADAlcohol dehydrogenase, propanol-preferring1.1.1.10.443
4kl9NDPDihydrofolate reductase1.5.1.30.443
4lk3NADUDP-glucuronic acid decarboxylase 14.1.1.350.443
4mvcCDCCholine-phosphate cytidylyltransferase A/0.443
4opiFDAConserved Archaeal protein/0.443
4q0kGA3Phytohormone-binding protein/0.443
4xwrFADCholesterol oxidase1.1.3.60.443
5a4vQUEGlutathione S-transferase F22.5.1.180.443
5c3zACPRibokinase/0.443
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.443
6ctsCICCitrate synthase, mitochondrial2.3.3.10.443
6tmn0PIThermolysin3.4.24.270.443
8dfrNDPDihydrofolate reductase1.5.1.30.443
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.442
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.442
1esvLARActin, alpha skeletal muscle/0.442
1jbpADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.442
1vikBAYGag-Pol polyprotein/0.442
1wvgCXYCDP-glucose 4,6-dehydratase4.2.1.450.442
1zptFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.442
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2g263LGRenin3.4.23.150.442
2pj4414Carboxypeptidase B/0.442
2q153MRBeta-secretase 13.4.23.460.442
2wdzNADGalactitol dehydrogenase/0.442
3fktSIIBeta-secretase 13.4.23.460.442
3gi5K62Gag-Pol polyprotein/0.442
3ioeA7DPantothenate synthetase6.3.2.10.442
3kkzSAMUncharacterized protein/0.442
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.442
3o0oGDPVitamin B12-dependent ribonucleotide reductase/0.442
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.442
3q33ACOHistone acetyltransferase RTT1092.3.1.480.442
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.442
3tqhNDPQuinone oxidoreductase/0.442
3uceNDPDehydrogenase/0.442
4bfvZVVPantothenate kinase2.7.1.330.442
4blsAPCNTPase P4/0.442
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.442
4f9fGDPPutative glycosyltransferase/0.442
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.442
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.442
4l98LRGPeroxisome proliferator-activated receptor gamma/0.442
4ntdFADThioredoxin reductase/0.442
5dp2NAPCurF/0.442
5ftfADPTPR domain protein/0.442
5ifiPRXAcetyl-coenzyme A synthetase/0.442
5jjsSAHGenome polyprotein/0.442
1a8t061Metallo-beta-lactamase type 2/0.441
1bim0QBRenin3.4.23.150.441
1gcoNADGlucose 1-dehydrogenase1.1.1.470.441
1icpFMN12-oxophytodienoate reductase 11.3.1.420.441
1kvkATPMevalonate kinase2.7.1.360.441
1olmVTQSEC14-like protein 2/0.441
1w4aAPCNTPase P4/0.441
1xdpATPPolyphosphate kinase/0.441
1xg5NAPDehydrogenase/reductase SDR family member 11/0.441
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.441
2a94AP0L-lactate dehydrogenase1.1.1.270.441
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.441
2fiwACOGCN5-related N-acetyltransferase:Aminotransferase, class-II/0.441
2fy4COACholine O-acetyltransferase2.3.1.60.441
2hg1N5OEndoplasmin/0.441
2j09FMNDeoxyribodipyrimidine photo-lyase4.1.99.30.441
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
2x3jATPAcsD/0.441
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
3bbrBHYGlutamate receptor 2/0.441
3coz54HPantothenate synthetase6.3.2.10.441
3da1FADGlycerol-3-phosphate dehydrogenase/0.441
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.441
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.441
3lpiZ74Beta-secretase 13.4.23.460.441
3pgiF41Endothiapepsin3.4.23.220.441
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.441
3r95ACOMccE protein/0.441
4b0532DBeta-secretase 13.4.23.460.441
4bizADPSensor histidine kinase CpxA/0.441
4ctaATPCinA-like protein/0.441
4en4ATPPyridoxal kinase2.7.1.350.441
4eyfPNKMetallo-beta-lactamase type 2/0.441
4kwi1TJReductase homolog/0.441
4olfHFGProline--tRNA ligase6.1.1.150.441
4uckSAMLarge structural protein/0.441
4z0g5GPInosine-5'-monophosphate dehydrogenase/0.441
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
5cwa0GAAnthranilate synthase component 14.1.3.270.441
5dc5B3NHistone deacetylase 83.5.1.980.441
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.441
1hbvGANGag-Pol polyprotein/0.440
1qrtATPGlutamine--tRNA ligase6.1.1.180.440
1tllFMNNitric oxide synthase, brain1.14.13.390.440
1uopGLY_PHE_GLU_PROProlyl endopeptidase3.4.21.260.440
1v25ANPLong-chain-fatty-acid--CoA ligase6.2.1.30.440
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.440
2ar8FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.440
2d1sSLULuciferin 4-monooxygenase1.13.12.70.440
2f3rG5PGuanylate kinase2.7.4.80.440
2fhyA37Fructose-1,6-bisphosphatase 13.1.3.110.440
2gs9SAHUncharacterized protein/0.440
2ifaFMNUncharacterized protein/0.440
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.440
2nuaCOASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.440
2pk3GDDGDP-6-deoxy-D-mannose reductase/0.440
2pr5FMNBlue-light photoreceptor/0.440
2qn7HBZGlycogen phosphorylase, muscle form2.4.1.10.440
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.440
2uxwTH3Very long-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.90.440
2xtnGTPGTPase IMAP family member 2/0.440
2xuiTZ5Acetylcholinesterase3.1.1.70.440
2xx91NFGlutamate receptor 2/0.440
2yyuC5POrotidine 5'-phosphate decarboxylase/0.440
3af0GDPPantothenate kinase2.7.1.330.440
3hl0NADMaleylacetate reductase/0.440
3lpgZ78Beta-glucuronidase3.2.1.310.440
3nf4FADAcyl-CoA dehydrogenase domain-containing protein/0.440
3nwzCOABH2602 protein/0.440
3t7sSAMUncharacterized protein/0.440
3v0p4GWHisto-blood group ABO system transferase/0.440
3vqsJT1Genome polyprotein/0.440
3wswNADL-lactate dehydrogenase/0.440
3x2vATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
4c1fX8ZMetallo-beta-lactamase type 2/0.440
4d03NAPPhenylacetone monooxygenase1.14.13.920.440
4de00JBBeta-lactamase/0.440
4gl4NAIAlcohol dehydrogenase class-3/0.440
4hjoAQ4Epidermal growth factor receptor2.7.10.10.440
4hx519VCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
4l5b1UXDeoxycytidine kinase2.7.1.740.440
4m99ACOUDP-N-acetylgalactosaminyltransferase/0.440
4na4A1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.440
4p8rNADGlyceraldehyde-3-phosphate dehydrogenase/0.440
4pzrCOAHistone acetyltransferase p300/0.440
4xyeNADFormate dehydrogenase/0.440
4y9xUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.440
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.440
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.440
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.440
5caeCOASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.440
5ftcADPTPR domain protein/0.440
5hxwFADL-amino acid deaminase/0.440