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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1ohoEQUSteroid Delta-isomerase5.3.3.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1ohoEQUSteroid Delta-isomerase5.3.3.11.000
1gs3EQUSteroid Delta-isomerase5.3.3.10.684
3owsEQUSteroid Delta-isomerase5.3.3.10.617
1cqsEQUSteroid Delta-isomerase5.3.3.10.601
1ogxEQUSteroid Delta-isomerase5.3.3.10.590
1e3rANDSteroid Delta-isomerase5.3.3.10.570
3iptEQUSteroid Delta-isomerase5.3.3.10.569
3owyEQUSteroid Delta-isomerase5.3.3.10.562
3owuEQUSteroid Delta-isomerase5.3.3.10.559
3fzwEQUSteroid Delta-isomerase5.3.3.10.552
1e3vDXCSteroid Delta-isomerase5.3.3.10.544
4jdaA9SAbscisic acid receptor PYL3/0.525
3c14FOKAdenylate cyclase type 2/0.524
3c14FOKAdenylate cyclase type 5/0.524
1fmjRTLRetinol dehydratase/0.521
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.520
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.519
2fpcSCGStrictosidine synthase4.3.3.20.517
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.517
2w4qCBWProstaglandin reductase 21.3.1.480.514
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.513
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.512
1oh0EQUSteroid Delta-isomerase5.3.3.10.511
1w6yEQUSteroid Delta-isomerase5.3.3.10.511
4qa0SHHHistone deacetylase 83.5.1.980.511
1xuoLA1Integrin alpha-L/0.510
2g1n1IGRenin3.4.23.150.509
1cjkFOKAdenylate cyclase type 2/0.508
1cjkFOKAdenylate cyclase type 5/0.508
3akn11DFatty acid-binding protein, intestinal/0.508
1iiuRTLRetinol-binding protein 4/0.507
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.507
3tfq07MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.507
4l1xSTRAldo-keto reductase family 1 member C2/0.507
1pd8CO4Dihydrofolate reductase1.5.1.30.506
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.506
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.506
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.506
3t8xT8XT-cell surface glycoprotein CD1b/0.506
4ax8ADPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.506
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.505
1culFOKAdenylate cyclase type 2/0.504
1culFOKAdenylate cyclase type 5/0.504
1m13HYFNuclear receptor subfamily 1 group I member 2/0.504
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.504
3c15FOKAdenylate cyclase type 2/0.502
3c15FOKAdenylate cyclase type 5/0.502
3up0D7SaceDAF-12/0.502
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.502
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.502
4ap1NAPSteroid monooxygenase/0.501
1osvCHCBile acid receptor/0.500
1tl7FOKAdenylate cyclase type 2/0.500
1tl7FOKAdenylate cyclase type 5/0.500
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.500
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.500
2ea2F77Methionine aminopeptidase 2/0.499
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.499
3iogSDFMetallo-beta-lactamase type 2/0.499
4qa1B3NHistone deacetylase 83.5.1.980.499
5dc5B3NHistone deacetylase 83.5.1.980.499
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.498
1cjvFOKAdenylate cyclase type 2/0.497
1cjvFOKAdenylate cyclase type 5/0.497
3p99LNPLanosterol 14-alpha-demethylase/0.497
4a81DXCMajor pollen allergen Bet v 1-A/0.497
1l8qADPChromosomal replication initiator protein DnaA/0.496
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.496
3c16FOKAdenylate cyclase type 2/0.496
3c16FOKAdenylate cyclase type 5/0.496
4l9q9TPSerum albumin/0.496
4qa2SHHHistone deacetylase 83.5.1.980.496
2gvdFKPAdenylate cyclase type 2/0.495
2gvdFKPAdenylate cyclase type 5/0.495
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.495
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.494
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.494
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.494
4psbGA3Cytokinin-specific binding protein/0.494
1eioGCHGastrotropin/0.493
1qjgEQUSteroid Delta-isomerase5.3.3.10.493
2wo7ASVIsopenicillin N synthase1.21.3.10.493
4bb3KKAIsopenicillin N synthase1.21.3.10.493
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.492
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.492
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.491
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.491
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.490
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.490
3k47D09Dihydrofolate reductase1.5.1.30.490
3zoiM2WIsopenicillin N synthase1.21.3.10.490
1ot7CHCBile acid receptor/0.489
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.489
2xviFADPutative flavin-containing monooxygenase/0.489
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.489
4gtt7TQGeranylgeranyl transferase type-2 subunit beta2.5.1.600.489
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.489
1ay0TPPTransketolase 12.2.1.10.488
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.488
3ezpB3NHistone deacetylase 83.5.1.980.488
3koo24DBifunctional epoxide hydrolase 23.3.2.100.488
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.488
3nxyD2HDihydrofolate reductase1.5.1.30.488
4dhyS41Glucokinase2.7.1.20.488
1obnASVIsopenicillin N synthase1.21.3.10.487
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.487
3jpuTY4Transcriptional activator protein LasR/0.487
4c2pX8ZAngiotensin-converting enzyme3.2.10.487
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.486
4jlm1NNDeoxycytidine kinase2.7.1.740.486
2a9z26AAdenosine kinase2.7.1.200.485
3fhxPXLPyridoxal kinase2.7.1.350.485
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.485
3h3r14HCollagen type IV alpha-3-binding protein/0.484
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.484
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.484
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.484
4iarERM5-hydroxytryptamine receptor 1B/0.484
4lb2DM5Serum albumin/0.484
1kquBR4Phospholipase A2, membrane associated/0.483
1lgtBP3Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.483
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.483
1sreHABStreptavidin/0.483
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.483
2rqfJH3Hemolymph juvenile hormone binding protein/0.483
3p9tTCLRepressor/0.483
1hb1OCVIsopenicillin N synthase1.21.3.10.482
1zg32HIIsoflavone 4'-O-methyltransferase/0.482
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.482
2y6fM9FIsopenicillin N synthase1.21.3.10.482
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.482
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.482
3h3t16HCollagen type IV alpha-3-binding protein/0.482
3lu8IQXSerum albumin/0.482
3vtcTK3Vitamin D3 receptor/0.482
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.482
4jvnYUGEstrogen sulfotransferase2.8.2.40.482
1s3wTQTDihydrofolate reductase1.5.1.30.481
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.481
2r0pK2CPutative FAD-monooxygenase/0.481
3junAKDPhenazine biosynthesis protein A/B/0.481
4jq2SUZAldo-keto reductase family 1 member C2/0.481
4lsjLSJGlucocorticoid receptor/0.481
1oc1ASVIsopenicillin N synthase1.21.3.10.480
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.480
1swtBTNStreptavidin/0.480
2vcmM11Isopenicillin N synthase1.21.3.10.480
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
3h3qH13Collagen type IV alpha-3-binding protein/0.480
3ov4EQUSteroid Delta-isomerase5.3.3.10.480
3vgnFNNSteroid Delta-isomerase5.3.3.10.480
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.479
1cjtFOKAdenylate cyclase type 2/0.479
1cjtFOKAdenylate cyclase type 5/0.479
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
1yw8A75Methionine aminopeptidase 2/0.479
2on6IMHPurine nucleoside phosphorylase2.4.2.10.479
2vrbNAPTriphenylmethane reductase/0.479
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.479
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.479
3jzfJZKBiotin carboxylase6.3.4.140.479
3v1s0LHStrictosidine synthase4.3.3.20.479
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.478
2iviACWIsopenicillin N synthase1.21.3.10.478
2vbpVB1Isopenicillin N synthase1.21.3.10.478
3bl7DD1m7GpppX diphosphatase3.6.1.590.478
4a83DXCMajor pollen allergen Bet v 1-A/0.478
4bfvZVVPantothenate kinase2.7.1.330.478
4klaCHDFerrochelatase, mitochondrial4.99.1.10.478
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.477
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.477
1yhjR6CPyridoxal kinase2.7.1.350.477
2po7CHDFerrochelatase, mitochondrial4.99.1.10.477
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.477
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.477
3g8eIS1Nicotinamide phosphoribosyltransferase2.4.2.120.477
3s41S41Glucokinase2.7.1.20.477
3up3XCAaceDAF-12/0.477
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.477
4hu1V13Carbonic anhydrase 134.2.1.10.477
1r8qAFBCytohesin-2/0.476
1r8qAFBADP-ribosylation factor 1/0.476
1vkgCRIHistone deacetylase 83.5.1.980.476
2acwUPGGlycosyltransferase/0.476
2zymACXPeriplasmic binding protein/0.476
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.476
3mytEQUSteroid Delta-isomerase5.3.3.10.476
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.476
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.476
4ddrMMVDihydrofolate reductase1.5.1.30.476
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.476
4iyg1HUStrictosidine synthase4.3.3.20.476
4pkwGM6Lethal factor3.4.24.830.476
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.475
3c3dFO12-phospho-L-lactate transferase/0.475
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.475
3nxrD2DDihydrofolate reductase1.5.1.30.475
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.475
3zkyWT4Isopenicillin N synthase1.21.3.10.475
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.475
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.475
4m6l21VDihydrofolate reductase1.5.1.30.475
1rd4L08Integrin alpha-L/0.474
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.474
2fzjDH3Dihydrofolate reductase1.5.1.30.474
3ahiHTLProbable phosphoketolase/0.474
3f63GTXGlutathione transferase GST1-4/0.474
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.474
4h9753SDihydrofolate reductase1.5.1.30.474
5hs1VORLanosterol 14-alpha demethylase/0.474
1bk0ACVIsopenicillin N synthase1.21.3.10.473
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.473
1felFENRetinol-binding protein 4/0.473
1t7o152Carnitine O-acetyltransferase2.3.1.70.473
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
3nj0PYVAbscisic acid receptor PYL2/0.473
3pqbVGPPutative oxidoreductase/0.473
3rthRTHBeta-secretase 13.4.23.460.473
3sl2ATPSensor histidine kinase WalK/0.473
4aosNAPSteroid monooxygenase/0.473
4dsbA8SAbscisic acid receptor PYL3/0.473
4mv4ACPBiotin carboxylase6.3.4.140.473
5d1bTSNHistone deacetylase 83.5.1.980.473
5epoTUD7-alpha-hydroxysteroid deydrogenase/0.473
1kt3RTLRetinol-binding protein 4/0.472
1ohkCOPDihydrofolate reductase1.5.1.30.472
1p0pBCHCholinesterase3.1.1.80.472
1qiqACCIsopenicillin N synthase1.21.3.10.472
1srfMTBStreptavidin/0.472
1trgCB3Thymidylate synthase/0.472
1xddAAYIntegrin alpha-L/0.472
2cahNDPCatalase1.11.1.60.472
3fhxPLPPyridoxal kinase2.7.1.350.472
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.472
2cekN8TAcetylcholinesterase3.1.1.70.471
2d06ESTSulfotransferase 1A12.8.2.10.471
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.471
2lbdREARetinoic acid receptor gamma/0.471
3gwfNAPCyclohexanone monooxygenase/0.471
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.471
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.471
4a33PS8Glycylpeptide N-tetradecanoyltransferase/0.471
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.471
4bfzZVZPantothenate kinase2.7.1.330.471
4ea13RXDehydrosqualene synthase/0.471
4ixd1HVIntegrin alpha-L/0.471
4ixeIXEDihydrofolate reductase1.5.1.30.471
1q13TESProstaglandin-E(2) 9-reductase1.1.1.1890.470
1rftPXMPyridoxal kinase2.7.1.350.470
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.470
1ygjRMCPyridoxal kinase2.7.1.350.470
1zgaHMKIsoflavone 4'-O-methyltransferase/0.470
2yatEEUEstrogen receptor/0.470
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.470
3w5p4OAVitamin D3 receptor/0.470
3zrbOR8Progesterone receptor/0.470
4ey6GNTAcetylcholinesterase3.1.1.70.470
4trj665Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.470
1al7HSTPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.469
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.469
1mczRMNBenzoylformate decarboxylase4.1.1.70.469
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.469
1tkcM6TTransketolase 12.2.1.10.469
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
2bu9HFVIsopenicillin N synthase1.21.3.10.469
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
2zynBCDPeriplasmic binding protein/0.469
3gncQQQGlutaryl-CoA dehydrogenase/0.469
3nuvASDSteroid Delta-isomerase5.3.3.10.469
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.469
4dbs0HVAldo-keto reductase family 1 member C3/0.469
4h9506UDihydrofolate reductase1.5.1.30.469
4jq4IMNAldo-keto reductase family 1 member C2/0.469
2yczI32Beta-1 adrenergic receptor/0.469
1brpRTLRetinol-binding protein 4/0.468
1h36R88Squalene--hopene cyclase4.2.1.1290.468
1hb3SCVIsopenicillin N synthase1.21.3.10.468
1r58AO5Methionine aminopeptidase 2/0.468
1yhoTRRDihydrofolate reductase1.5.1.30.468
2b58COADiamine acetyltransferase 1/0.468
2jb4A14Isopenicillin N synthase1.21.3.10.468
2vqoTFGHistone deacetylase 43.5.1.980.468
3ghvGHCDihydrofolate reductase1.5.1.30.468
3kxoKXOHematopoietic prostaglandin D synthase/0.468
3lfeZ84Mitogen-activated protein kinase 14/0.468
3maaFKPAdenylate cyclase type 2/0.468
3maaFKPAdenylate cyclase type 5/0.468
3ntz3TZDihydrofolate reductase1.5.1.30.468
3vtbTKAVitamin D3 receptor/0.468
4jtrIBPAldo-keto reductase family 1 member C2/0.468
4ktl1CQCytochrome P450/0.468
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.468
1mrqSTRAldo-keto reductase family 1 member C1/0.467
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.467
2ociTYCValacyclovir hydrolase3.10.467
3bfa9ODOdorant binding protein ASP1/0.467
3gwfFADCyclohexanone monooxygenase/0.467
4bfxZVXPantothenate kinase2.7.1.330.467
4g090VDHistidinol dehydrogenase/0.467
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.467
4jbtASDCytochrome P450 monooxygenase/0.467
4kebFOLDihydrofolate reductase1.5.1.30.467
4qoeFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.467
4xwtU5PRibonuclease J/0.467
1sr7MOFProgesterone receptor/0.466
1thnADPAnti-sigma F factor/0.466
1u2rSO1Elongation factor 2/0.466
1uzwCDHIsopenicillin N synthase1.21.3.10.466
1yw7A41Methionine aminopeptidase 2/0.466
2ea4F79Methionine aminopeptidase 2/0.466
2gv8NDPThiol-specific monooxygenase1.14.130.466
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.466
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3fnu006HAP protein/0.466
3nfrEWQRibosyldihydronicotinamide dehydrogenase [quinone]/0.466
3stdMQ0Scytalone dehydratase4.2.1.940.466
3tk3CPZCytochrome P450 2B41.14.14.10.466
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.466
3vf60H6Glucokinase2.7.1.20.466
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.466
4cdmFO1Deoxyribodipyrimidine photolyase/0.466
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.466
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.466
4iwv1J9Glucokinase2.7.1.20.466
4j7xSASSepiapterin reductase1.1.1.1530.466
4jlj1NMDeoxycytidine kinase2.7.1.740.466
1e7aPFLSerum albumin/0.465
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.465
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.465
2y60M8FIsopenicillin N synthase1.21.3.10.465
2y67N21UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.465
3acy702Dehydrosqualene synthase/0.465
3fazNOSPurine nucleoside phosphorylase/0.465
3rvhHQ2Lysine-specific demethylase 4A1.14.110.465
3u8hBHPPhospholipase A2, membrane associated/0.465
4fhd0TTSpore photoproduct lyase/0.465
4rrcA3TProbable threonine--tRNA ligase 26.1.1.30.465
1cqp803Integrin alpha-L/0.464
1p8dCO1Oxysterols receptor LXR-beta/0.464
1re9DSOCamphor 5-monooxygenase1.14.15.10.464
1tkaN3TTransketolase 12.2.1.10.464
1yw9A84Methionine aminopeptidase 2/0.464
2a9y26AAdenosine kinase2.7.1.200.464
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
2oliIOPBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.464
2oyfIACBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.464
2uupLK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.464
2zjwREFCasein kinase II subunit alpha2.7.11.10.464
3c3xNAPEugenol synthase 11.1.1.3180.464
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.464
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.464
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.464
3l6jZ90Alr2278 protein/0.464
3lkhLT6Genome polyprotein2.7.7.480.464
3lxeTORCarbonic anhydrase 14.2.1.10.464
3nhpHGZRibosyldihydronicotinamide dehydrogenase [quinone]/0.464
4ea2RWZDehydrosqualene synthase/0.464
4iae1DXAlr2278 protein/0.464
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.464
5c1mCLRMu-type opioid receptor/0.464
1b4vFADCholesterol oxidase1.1.3.60.463
1cjuFOKAdenylate cyclase type 2/0.463
1cjuFOKAdenylate cyclase type 5/0.463
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.463
1ndzFR5Adenosine deaminase3.5.4.40.463
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.463
1o5rFR9Adenosine deaminase3.5.4.40.463
1p33MTXPteridine reductase 11.5.1.330.463
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
2zb45OPProstaglandin reductase 21.3.1.480.463
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.463
3oqfS51Renin3.4.23.150.463
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
4g3jVNTLanosterol 14-alpha-demethylase/0.463
5iw5NMNNADH pyrophosphatase/0.463
1jraFADFAD-linked sulfhydryl oxidase ERV21.8.3.20.462
1kt5RTLRetinol-binding protein 4/0.462
1olmVTQSEC14-like protein 2/0.462
1w22NHBHistone deacetylase 83.5.1.980.462
2bxqIMNSerum albumin/0.462
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
2z7gEH9Adenosine deaminase3.5.4.40.462
3rmeRMEAcidic mammalian chitinase3.2.1.140.462
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.462
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.462
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.462
4jvmXDIEstrogen sulfotransferase2.8.2.40.462
1eirBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.461
1kt6RTLRetinol-binding protein 4/0.461
1lkdBP6Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.461
1ve3SAMUncharacterized protein/0.461
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
2ga2A19Methionine aminopeptidase 2/0.461
2hvcLGDAndrogen receptor/0.461
2jfz003Glutamate racemase/0.461
2rhrEMOPutative ketoacyl reductase1.3.10.461
2wd8VGFPteridine reductase/0.461
3c3eFO12-phospho-L-lactate transferase/0.461
3ed1GA3Gibberellin receptor GID1/0.461
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3vtdTKDVitamin D3 receptor/0.461
4bfsZVSPantothenate kinase2.7.1.330.461
4c717RD3-oxoacyl-ACP synthase/0.461
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.461
1kl2FONSerine hydroxymethyltransferase/0.460
1kmyBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.460
1qxlFR8Adenosine deaminase3.5.4.40.460
1sbrVIBPutative HMP/thiamine-binding protein YkoF/0.460
2a5c8DAAvidin/0.460
2g247IGRenin3.4.23.150.460
2xf3J01Uncharacterized protein/0.460
2z2w770Wee1-like protein kinase2.7.10.20.460
2zb8IMNProstaglandin reductase 21.3.1.480.460
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.460
4hwkSFYSepiapterin reductase1.1.1.1530.460
4j6cSTRCytochrome P450 monooxygenase/0.460
4jvlESTEstrogen sulfotransferase2.8.2.40.460
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.460
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.460
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.459
1ihiIU5Aldo-keto reductase family 1 member C2/0.459
1kmvLIIDihydrofolate reductase1.5.1.30.459
1rzuADPGlycogen synthase 12.4.1.210.459
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.459
2ab8MTPAdenosine kinase2.7.1.200.459
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.459
2nn7M29Carbonic anhydrase 14.2.1.10.459
2qdsMCOMetallo-beta-lactamase type 2/0.459
3apwDP0Alpha-1-acid glycoprotein 2/0.459
3bejMUFBile acid receptor/0.459
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.459
3l8sBFFMitogen-activated protein kinase 14/0.459
3s3vTOPDihydrofolate reductase1.5.1.30.459
3uk6ADPRuvB-like 23.6.4.120.459
3w0yDS4Vitamin D3 receptor/0.459
3zv7NHGAcetylcholinesterase3.1.1.70.459
4bfuZVUPantothenate kinase2.7.1.330.459
4eji0QACytochrome P450 2A131.14.14.10.459
4k4j1O8Retinoic acid receptor RXR-alpha/0.459
4l5b1UXDeoxycytidine kinase2.7.1.740.459
4pb25UDNucleoside permease/0.459
5ab7MLCNonspecific lipid-transfer protein, putative/0.459
5stdUNNScytalone dehydratase4.2.1.940.459
1cs4FOKAdenylate cyclase type 2/0.458
1cs4FOKAdenylate cyclase type 5/0.458
1n5vNOMActVA 6 protein/0.458
1puaCOAHAT A1/0.458
1uhhCZPAequorin-2/0.458
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
2uuoLK3UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.458
2x9vTMQPteridine reductase/0.458
3elm24FCollagenase 33.4.240.458
3mdmFJZCholesterol 24-hydroxylase/0.458
4exsX8ZMetallo-beta-lactamase type 2/0.458
4ez8DHFThymidylate synthase2.1.1.450.458
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.458
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.458
4isg1FYGlucokinase2.7.1.20.458
4jsgQ10Nitric oxide synthase, brain1.14.13.390.458
4k4eK4ETankyrase-12.4.2.300.458
4kak06UDihydrofolate reductase1.5.1.30.458
4xbfFADLysine-specific histone demethylase 1A10.458
1axwMTXThymidylate synthase/0.457
1dv2ATPBiotin carboxylase6.3.4.140.457
1ej3CZHAequorin-2/0.457
1fcy564Retinoic acid receptor gamma/0.457
1o6qR17Squalene--hopene cyclase4.2.1.1290.457
1x1cSAHC-20 methyltransferase/0.457
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.457
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.457
2hxdDUPdCTP deaminase, dUMP-forming3.5.4.300.457
2o7pNAPRiboflavin biosynthesis protein RibD/0.457
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.457
2xy93ESAngiotensin-converting enzyme3.2.10.457
3acw651Dehydrosqualene synthase/0.457
3arvSAUChitinase A/0.457
3cgyRDCVirulence sensor histidine kinase PhoQ2.7.13.30.457
3fmz2T1Retinol-binding protein 4/0.457
3h3sH15Collagen type IV alpha-3-binding protein/0.457
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.457
3hywDCQSulfide-quinone reductase/0.457
3w5tLHPVitamin D3 receptor/0.457
4c1fX8ZMetallo-beta-lactamase type 2/0.457
4g2h0VQVitamin D3 receptor A/0.457
4uymVOR14-alpha sterol demethylase Cyp51B/0.457
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.457
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.457
5irnADPNucleotide binding oligomerization domain containing 2/0.457
1dkfBMSRetinoic acid receptor alpha/0.456
1g3mPCQEstrogen sulfotransferase2.8.2.40.456
1hfrMOTDihydrofolate reductase1.5.1.30.456
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
1lrhNLAAuxin-binding protein 1/0.456
1ly4COQDihydrofolate reductase1.5.1.30.456
1pq944BOxysterols receptor LXR-beta/0.456
1rx6DDFDihydrofolate reductase1.5.1.30.456
1w06W05Isopenicillin N synthase1.21.3.10.456
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.456
2tscCB3Thymidylate synthase/0.456
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.456
3d74NBBPheromone-binding protein ASP1/0.456
3fsuC2F5,10-methylenetetrahydrofolate reductase1.5.1.200.456
3g5hYTTMycocyclosin synthase1.14.21.90.456
3ghh2NFCD38 molecule/0.456
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3lm4HPXCatechol 2,3-dioxygenase/0.456
3q2mCKISpectinomycin phosphotransferase/0.456
3w2eFADNADH-cytochrome b5 reductase 31.6.2.20.456
4dc0NDPPutative ketoacyl reductase1.3.10.456
4j6dTESCytochrome P450 monooxygenase/0.456
4n4v2GYTankyrase-12.4.2.300.456
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.455
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1i9hBNIStreptavidin/0.455
1o6rR19Squalene--hopene cyclase4.2.1.1290.455
1rdtL79Retinoic acid receptor RXR-alpha/0.455
1re0AFBADP-ribosylation factor 1/0.455
1re0AFBARF guanine-nucleotide exchange factor 1/0.455
1s9dAFBCytohesin-2/0.455
1s9dAFBADP-ribosylation factor 1/0.455
1tg56454-hydroxyphenylpyruvate dioxygenase1.13.11.270.455
1x8lOXRRetinol dehydratase/0.455
2iluNDPLactaldehyde dehydrogenase1.2.1.220.455
2lbaCHOFatty acid binding protein 6/0.455
2mjiKTRFatty acid-binding protein, intestinal/0.455
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
2p1t3TNRetinoic acid receptor RXR-alpha/0.455
2zevB71Geranylgeranyl pyrophosphate synthase/0.455
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.455
3da24MDCarbonic anhydrase 134.2.1.10.455
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.455
3eon341Glutaryl-CoA dehydrogenase/0.455
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.455
3hl0NADMaleylacetate reductase/0.455
3imxB84Glucokinase2.7.1.20.455
3oqkS52Renin3.4.23.150.455
3p3zP3ZPutative cytochrome P450/0.455
3pz3PZ3Geranylgeranyl transferase type-2 subunit beta2.5.1.600.455
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.455
4iah1DXAlr2278 protein/0.455
4jq3ZOMAldo-keto reductase family 1 member C2/0.455
4kfj1R0Dihydrofolate reductase1.5.1.30.455
4n1gCEIObelin/0.455
1aoeGW3Dihydrofolate reductase1.5.1.30.454
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.454
1hfqMOTDihydrofolate reductase1.5.1.30.454
1mvsDTMDihydrofolate reductase1.5.1.30.454
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.454
1s36CEIObelin/0.454
1ygkRRCPyridoxal kinase2.7.1.350.454
2braFAD[F-actin]-methionine sulfoxide oxidase MICAL11.14.130.454
2hnzPC0Gag-Pol polyprotein2.7.7.490.454
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.454
2obxINI6,7-dimethyl-8-ribityllumazine synthase 22.5.1.780.454
2q9fC3SCholesterol 24-hydroxylase/0.454
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.454
3oafOAGDihydrofolate reductase1.5.1.30.454
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
3vt7VDXVitamin D3 receptor/0.454
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.454
4f6w0SSCyclin-dependent kinase 82.7.11.220.454
4k5fQ14Nitric oxide synthase, brain1.14.13.390.454
4qofFMNRibosyldihydronicotinamide dehydrogenase [quinone]/0.454
5fmmMGTPolymerase basic protein 2/0.454
3sn6P0GBeta-2 adrenergic receptor/0.454
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
1dgfNDPCatalase1.11.1.60.453
1h9zRWFSerum albumin/0.453
1jtuLYBThymidylate synthase/0.453
1kqwRTLCellular retinol-binding protein type II/0.453
1opbRETRetinol-binding protein 2/0.453
1tysDHFThymidylate synthase/0.453
1zprCB3Thymidylate synthase/0.453
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.453
2iko7IGRenin3.4.23.150.453
3csdEMOPutative ketoacyl reductase1.3.10.453
3d76NBBPheromone-binding protein ASP1/0.453
3nxvD2FDihydrofolate reductase1.5.1.30.453
3occDIHPurine nucleoside phosphorylase DeoD-type/0.453
3pl8FADPyranose 2-oxidase/0.453
4a6rTA8Probable aminotransferase/0.453
4b1fKRHGlutamate racemase/0.453
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.453
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.453
1tg2H2BPhenylalanine-4-hydroxylase1.14.16.10.452
1z4iUMP5'(3')-deoxyribonucleotidase, mitochondrial3.1.30.452
2g1y5IGRenin3.4.23.150.452
2hzqSTRApolipoprotein D/0.452
2il2LIXRenin3.4.23.150.452
2jn3JN3Fatty acid-binding protein, liver/0.452
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.452
2v5xV5XHistone deacetylase 83.5.1.980.452
2xtbKRMAdenosine kinase, putative/0.452
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.452
3akm11DFatty acid-binding protein, intestinal/0.452
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.452
3h18PMSEsterase/lipase/0.452
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
3ixp834Ecdysone receptor/0.452
3juqAKDPhenazine biosynthesis protein A/B/0.452
3l0lHC3Nuclear receptor ROR-gamma/0.452
3nlw3XFNitric oxide synthase, brain1.14.13.390.452
3p8iFMNPentaerythritol tetranitrate reductase/0.452
3pd3A3TThreonine--tRNA ligase6.1.1.30.452
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.452
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.452
4lgaA2OAbscisic acid receptor PYL2/0.452
4mv1ADPBiotin carboxylase6.3.4.140.452
4nieNBHNuclear receptor ROR-gamma/0.452
4o701QKBromodomain-containing protein 4/0.452
1crbRTLRetinol-binding protein 1/0.451
1ep4S11Gag-Pol polyprotein2.7.7.490.451
1fmlRTLRetinol dehydratase/0.451
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.451
1gt5BZQOdorant-binding protein/0.451
1kmsLIHDihydrofolate reductase1.5.1.30.451
1mxfMTXPutative pteridine reductase 2/0.451
1pd9CO4Dihydrofolate reductase1.5.1.30.451
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.451
2hcdBIVVitamin D3 receptor A/0.451
2i4qUA4Renin3.4.23.150.451
2imfTOM2-hydroxychromene-2-carboxylate isomerase5.99.1.40.451
3br3ETHTH-type transcriptional regulator QacR/0.451
3cz09ODPheromone-binding protein ASP1/0.451
3jq8DX3Pteridine reductase, putative/0.451
3l3rOAGDihydrofolate reductase1.5.1.30.451
3nxtD2EDihydrofolate reductase1.5.1.30.451
3otwCOAPhosphopantetheine adenylyltransferase/0.451
3tptADPSerine/threonine-protein kinase toxin HipA/0.451
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.451
4bfyZVYPantothenate kinase2.7.1.330.451
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.451
4dscA8SAbscisic acid receptor PYL3/0.451
4g1d0VKVitamin D3 receptor A/0.451
4ia3BIVVitamin D3 receptor A/0.451
4ips1G4Mycocyclosin synthase1.14.21.90.451
4jlk1NODeoxycytidine kinase2.7.1.740.451
4jx1CAHCamphor 5-monooxygenase1.14.15.10.451
4n1fCZHObelin/0.451
4nv7COAArylamine N-acetyltransferase/0.451
5bp9SAHPutative methyltransferase protein/0.451
5c4fUPGHisto-blood group ABO system transferase/0.451
1kt4RTLRetinol-binding protein 4/0.450
1rkhVD2Vitamin D3 receptor/0.450
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.450
1ykdCMPAdenylate cyclase/0.450
2g0nGDPRas-related C3 botulinum toxin substrate 3/0.450
2g1s4IGRenin3.4.23.150.450
2gzl2AA2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.450
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.450
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.450
2oaxSNLMineralocorticoid receptor/0.450
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.450
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.450
2rds1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.450
2vb8TLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.450
2w71L23Biotin carboxylase6.3.4.140.450
2zsiGA4Gibberellin receptor GID1A30.450
3i0rRT3Gag-Pol polyprotein2.7.7.490.450
3jq6DX1Pteridine reductase, putative/0.450
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.450
3nmpPYVAbscisic acid receptor PYL2/0.450
3pm1ETHTH-type transcriptional regulator QacR/0.450
3qlzQLZUncharacterized protein/0.450
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.450
4e6a0O9Mitogen-activated protein kinase 14/0.450
4pahLNRPhenylalanine-4-hydroxylase1.14.16.10.450
5p2pDHGPhospholipase A2, major isoenzyme3.1.1.40.450
1fm69CRRetinoic acid receptor RXR-alpha/0.449
1lnmDTXBilin-binding protein/0.449
1pwuGM6Lethal factor3.4.24.830.449
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1tvrTB9Gag-Pol polyprotein2.7.7.490.449
1x1dSAHC-20 methyltransferase/0.449
2ab2SNLMineralocorticoid receptor/0.449
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.449
2g72F21Phenylethanolamine N-methyltransferase2.1.1.280.449
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.449
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.449
2x9dITCTetracycline repressor protein class D/0.449
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
3af1GDPPantothenate kinase2.7.1.330.449
3bi6396Wee1-like protein kinase2.7.10.20.449
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
3fnhJPJEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
3kdiA8SAbscisic acid receptor PYL2/0.449
3nlv3XANitric oxide synthase, brain1.14.13.390.449
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.449
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.449
3vrwYS5Vitamin D3 receptor/0.449
4c9wVGH7,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.449
4ise1FWGlucokinase2.7.1.20.449
4jr51LSNicotinamide phosphoribosyltransferase2.4.2.120.449
4xo7ASDAldo-keto reductase family 1 member C2/0.449
5c93ACPTwo-component system histidine protein kinase/0.449
1db1VDXVitamin D3 receptor/0.448
1dduCB3Thymidylate synthase/0.448
1dr3HBIDihydrofolate reductase1.5.1.30.448
1gs4ZK5Androgen receptor/0.448
1qoqIGPTryptophan synthase alpha chain/0.448
1qtiGNTAcetylcholinesterase3.1.1.70.448
1sriDMBStreptavidin/0.448
1xdkREARetinoic acid receptor beta/0.448
2g8yNADHydroxycarboxylate dehydrogenase B/0.448
2hkoFADLysine-specific histone demethylase 1A10.448
2q153MRBeta-secretase 13.4.23.460.448
2rtdBTNStreptavidin/0.448
2v58LZJBiotin carboxylase6.3.4.140.448
2v59LZKBiotin carboxylase6.3.4.140.448
2w3mFOLDihydrofolate reductase1.5.1.30.448
3br2DEQHTH-type transcriptional regulator QacR/0.448
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.448
3d73NBBPheromone-binding protein ASP1/0.448
3d75NBBPheromone-binding protein ASP1/0.448
3e6c3C4Cyclic nucleotide-binding protein/0.448
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
3lakKR1Gag-Pol polyprotein2.7.7.490.448
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.448
3qiyQI1Botulinum neurotoxin type A3.4.24.690.448
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
3zraORBProgesterone receptor/0.448
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.448
4b4vL34Bifunctional protein FolD/0.448
4bchT7ZCyclin-dependent kinase 92.7.11.220.448
4eilCB3Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
4ejvLCLTranscriptional regulator TcaR/0.448
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.300.448
4jxxATPGlutamine--tRNA ligase6.1.1.180.448
4kbn25UDihydrofolate reductase1.5.1.30.448
4kx6FADFumarate reductase flavoprotein subunit1.3.5.40.448
4ubuCOASteroid 3-ketoacyl-CoA thiolase/0.448
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
5pahLDPPhenylalanine-4-hydroxylase1.14.16.10.448
1b2lNDCAlcohol dehydrogenase1.1.1.10.447
1db56INPhospholipase A2, membrane associated/0.447
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1pqc444Oxysterols receptor LXR-beta/0.447
1qzzSAMAclacinomycin 10-hydroxylase RdmB4.1.10.447
1t47NTD4-hydroxyphenylpyruvate dioxygenase1.13.11.270.447
1u72MTXDihydrofolate reductase1.5.1.30.447
1v79FR7Adenosine deaminase3.5.4.40.447
1x8vESLLanosterol 14-alpha demethylase1.14.13.700.447
2eixFADNADH-cytochrome b5 reductase/0.447
2flhZEACytokinin-specific binding protein/0.447
2p1u4TNRetinoic acid receptor RXR-alpha/0.447
2w6pOA4Biotin carboxylase6.3.4.140.447
3gamMXXRibosyldihydronicotinamide dehydrogenase [quinone]/0.447
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.447
4a2jAS0Progesterone receptor/0.447
4avlTMPPolymerase acidic protein/0.447
4g8cC6LAlpha/beta hydrolase fold protein/0.447
4ixc1JDGlucokinase2.7.1.20.447
4jbsP52Endoplasmic reticulum aminopeptidase 23.4.110.447
4k37SAMAnaerobic sulfatase-maturating enzyme1.8.980.447
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.447
4lt63ATPoly(A) polymerase gamma2.7.7.190.447
4lwwLWWNicotinamide phosphoribosyltransferase2.4.2.120.447
4p6wMOFGlucocorticoid receptor/0.447
4pd6URINucleoside permease/0.447
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.447
5cc9DDFDihydrofolate reductase1.5.1.30.447
1fm99CRRetinoic acid receptor RXR-alpha/0.446
1gky5GPGuanylate kinase2.7.4.80.446
1h50FMNPentaerythritol tetranitrate reductase/0.446
1hfpMOTDihydrofolate reductase1.5.1.30.446
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
1lcbDHFThymidylate synthase/0.446
1n83CLRNuclear receptor ROR-alpha/0.446
1r2jFADFkbI/0.446
1rtiHEFGag-Pol polyprotein2.7.7.490.446
1xlsREARetinoic acid receptor RXR-alpha/0.446
1xmmM7Gm7GpppX diphosphatase3.6.1.590.446
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.446
2fhnBNIAvidin-related protein 4/5/0.446
2hxzH7JCathepsin S3.4.22.270.446
2jedLG8Protein kinase C theta type2.7.11.130.446
2oc2RX3Angiotensin-converting enzyme3.2.10.446
2xveFADPutative flavin-containing monooxygenase/0.446
2ym1FADPhenylacetone monooxygenase1.14.13.920.446
3aosJH2Hemolymph juvenile hormone binding protein/0.446
3dl9V2HVitamin D 25-hydroxylase/0.446
3drrR8EGag-Pol polyprotein2.7.7.490.446
3ipq965Oxysterols receptor LXR-alpha/0.446
3own3OXRenin3.4.23.150.446
3ox279XRibosyldihydronicotinamide dehydrogenase [quinone]/0.446
3qj0QI3Botulinum neurotoxin type A3.4.24.690.446
3vswR31Renin3.4.23.150.446
3zkuHCVIsopenicillin N synthase1.21.3.10.446
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.446
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.446
4dkbDUNDeoxyuridine triphosphatase, putative/0.446
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4hmbPZZPhospholipase A2 VRV-PL-VIIIa/0.446
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.446
4iaq2GM5-hydroxytryptamine receptor 1B/0.446
4jtrIZPAldo-keto reductase family 1 member C2/0.446
4kykIMNLactoylglutathione lyase4.4.1.50.446
4rh10TTSpore photoproduct lyase/0.446
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.446
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.445
1h35R01Squalene--hopene cyclase4.2.1.1290.445
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
1s3uTQDDihydrofolate reductase1.5.1.30.445
1towCRZFatty acid-binding protein, adipocyte/0.445
1u65CP0Acetylcholinesterase3.1.1.70.445
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.445
2oz57XYUncharacterized protein/0.445
3bzuA21Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
3ddw055Glycogen phosphorylase, liver form2.4.1.10.445
3fsjD7KBenzoylformate decarboxylase4.1.1.70.445
3fwgCAMCamphor 5-monooxygenase1.14.15.10.445
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
3hy310F5-formyltetrahydrofolate cyclo-ligase6.3.3.20.445
3n0hTOPDihydrofolate reductase1.5.1.30.445
3p6oETGCamphor 5-monooxygenase1.14.15.10.445
3uleC69Actin-related protein 3/0.445
3v0m5GWHisto-blood group ABO system transferase/0.445
4b4w9L9Bifunctional protein FolD/0.445
4e0u0MVCyclic dipeptide N-prenyltransferase/0.445
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.445
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.445
4jseQJ2Nitric oxide synthase, brain1.14.13.390.445
4kfp1R7Nicotinamide phosphoribosyltransferase2.4.2.120.445
4lg5A1OAbscisic acid receptor PYL2/0.445
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.445
4zvnFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.445
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.445
1blzACVIsopenicillin N synthase1.21.3.10.444
1dlrMXADihydrofolate reductase1.5.1.30.444
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1iyzNDPProbable quinone oxidoreductase/0.444
1m8h6NINitric oxide synthase, inducible1.14.13.390.444
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.444
1qsnCOAHAT A1/0.444
1r5gAO1Methionine aminopeptidase 2/0.444
1ry0PG2Aldo-keto reductase family 1 member C3/0.444
1synF89Thymidylate synthase/0.444
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
1th6OINBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.444
1txiTX5Vitamin D3 receptor/0.444
1u1cBAUUridine phosphorylase2.4.2.30.444
1zz1SHHHistone deacetylase-like amidohydrolase3.5.10.444
2idoTMPDNA polymerase III subunit epsilon2.7.7.70.444
2j9gANPBiotin carboxylase6.3.4.140.444
2othNIMBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.444
2uxhQUEHTH-type transcriptional regulator TtgR/0.444
2uxiG50HTH-type transcriptional regulator TtgR/0.444
3antS82Bifunctional epoxide hydrolase 23.3.2.100.444
3e5aVX6Aurora kinase A2.7.11.10.444
3f3y4OABile salt sulfotransferase2.8.2.140.444
3gw9VNILanosterol 14-alpha-demethylase/0.444
3gwzSAHMitomycin biosynthesis 6-O-methyltransferase/0.444
3k1wBFXRenin3.4.23.150.444
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.444
3t3q9PLCytochrome P450 2A61.14.130.444
3w78CBDFMN-dependent NADH-azoreductase/0.444
3zrbORCProgesterone receptor/0.444
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
4fm80UQBeta-secretase 13.4.23.460.444
4isf1FXGlucokinase2.7.1.20.444
4itmATPTetraacyldisaccharide 4'-kinase/0.444
4kd79DRDihydrofolate reductase1.5.1.30.444
4l6gCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.444
4m6kFOLDihydrofolate reductase1.5.1.30.444
4q0kGA3Phytohormone-binding protein/0.444
3p0gP0GBeta-2 adrenergic receptor/0.444
1d2sDHTSex hormone-binding globulin/0.443
1ek2CDUBifunctional epoxide hydrolase 2/0.443
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
1hniAAAGag-Pol polyprotein2.7.7.490.443
1jumBERHTH-type transcriptional regulator QacR/0.443
1kvoOAPPhospholipase A2, membrane associated/0.443
1ly3COGDihydrofolate reductase1.5.1.30.443
1m78CLZDihydrofolate reductase1.5.1.30.443
1n0uSO1Elongation factor 2/0.443
1nhkCMPNucleoside diphosphate kinase2.7.4.60.443
1og5SWFCytochrome P450 2C9/0.443
1p6xTHMThymidine kinase/0.443
1qjfACSIsopenicillin N synthase1.21.3.10.443
1qruATPGlutamine--tRNA ligase6.1.1.180.443
1rf9DBRCamphor 5-monooxygenase1.14.15.10.443
1srjNABStreptavidin/0.443
1uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.443
1vrqFMNSubunit alpha of sarocosine oxidase/0.443
1vrqFMNSubunit beta of sarcosine oxidase/0.443
1w4lGL8Acetylcholinesterase3.1.1.70.443
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
2culFADGidA-related protein/0.443
2in6839Wee1-like protein kinase2.7.10.20.443
2p1v5TNRetinoic acid receptor RXR-alpha/0.443
2r59PH0Leukotriene A-4 hydrolase3.3.2.60.443
2vk8TPPPyruvate decarboxylase isozyme 1/0.443
2wqpWQPPolysialic acid capsule biosynthesis protein SiaC/0.443
3f03FMNPentaerythritol tetranitrate reductase/0.443
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.443
3ix4TX1Transcriptional activator protein LasR/0.443
3ogkOGKCoronatine-insensitive protein 1/0.443
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.443
3rpnGTXGlutathione S-transferase kappa 12.5.1.180.443
3s6aANPAdenosine monophosphate-protein transferase NmFic2.7.7.n10.443
3vg9ZMAAdenosine receptor A2a/0.443
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
3zr7OR8Progesterone receptor/0.443
4a84DXCMajor pollen allergen Bet v 1-A/0.443
4at2ASDPossible succinate dehydrogenase/0.443
4k5e1Q7Nitric oxide synthase, brain1.14.13.390.443
4klnAGSTransitional endoplasmic reticulum ATPase3.6.4.60.443
4m6p20RNicotinamide phosphoribosyltransferase2.4.2.120.443
4r1lADPPhenylacetate-coenzyme A ligase/0.443
1aqbRTLRetinol-binding protein 4/0.442
1bq1CB3Thymidylate synthase/0.442
1db48INPhospholipase A2, membrane associated/0.442
1fd0254Retinoic acid receptor gamma/0.442
1fm4DXCMajor pollen allergen Bet v 1-L/0.442
1jtqLY3Thymidylate synthase/0.442
1lkeDOGBilin-binding protein/0.442
1o2eANNPhospholipase A23.1.1.40.442
1pq6965Oxysterols receptor LXR-beta/0.442
1q5dEPBEpothilone C/D epoxidase1.140.442
1sqnNDRProgesterone receptor/0.442
1y6oMJIPhospholipase A2, major isoenzyme3.1.1.40.442
2avxHTFRegulatory protein SdiA/0.442
2ejzSAHDiphthine synthase/0.442
2fs4PZ1Renin3.4.23.150.442
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.442
2oazI96Methionine aminopeptidase 2/0.442
2rtoIMIStreptavidin/0.442
2uz2BTNAvd protein/0.442
2w6oOA3Biotin carboxylase6.3.4.140.442
2x06NADL-sulfolactate dehydrogenase/0.442
2x6o2TCTetracycline repressor protein class D/0.442
2xweAMFGlucosylceramidase3.2.1.450.442
2zsaADPPantothenate kinase2.7.1.330.442
3bgxMEFThymidylate synthase/0.442
3d78NBBPheromone-binding protein ASP1/0.442
3dds26BGlycogen phosphorylase, liver form2.4.1.10.442
3dejRXCCaspase-33.4.22.560.442
3dmjGWEPol protein/0.442
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3ghwGHWDihydrofolate reductase1.5.1.30.442
3gkjHC3Niemann-Pick C1 protein/0.442
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.442
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.442
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.442
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.442
3p84FMNPentaerythritol tetranitrate reductase/0.442
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.442
3rsv3RSBeta-secretase 13.4.23.460.442
3ufl508Beta-secretase 13.4.23.460.442
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3vt65YIVitamin D3 receptor/0.442
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.442
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.442
4bfwZVWPantothenate kinase2.7.1.330.442
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.442
4jqaID8Aldo-keto reductase family 1 member C2/0.442
4jsiQ05Nitric oxide synthase, brain1.14.13.390.442
4l8u9AZSerum albumin/0.442
4othDRNSerine/threonine-protein kinase N1/0.442
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.442
5fd8A5APutative carboxypeptidase yocD/0.442
5jlaNADPutative short-chain dehydrogenase/reductase/0.442
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.441
1ove358Mitogen-activated protein kinase 14/0.441
1s19MC9Vitamin D3 receptor/0.441
1yqj6NPMitogen-activated protein kinase 14/0.441
2g263LGRenin3.4.23.150.441
2hl2SSAThreonine--tRNA ligase6.1.1.30.441
2vd0D27Hematopoietic prostaglandin D synthase/0.441
2vn1FK5Peptidylprolyl isomerase/0.441
2vqqTFGHistone deacetylase 43.5.1.980.441
2vz0D64Pteridine reductase/0.441
2w98P1ZProstaglandin reductase 21.3.1.480.441
2xvw9NRSerum albumin/0.441
3clxX22E3 ubiquitin-protein ligase XIAP6.3.20.441
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.441
3h8cNSZCathepsin L13.4.22.150.441
3hx3RETRetinaldehyde-binding protein 1/0.441
3ix8TX3Transcriptional activator protein LasR/0.441
3n83ADPAldehyde dehydrogenase, mitochondrial1.2.1.30.441
3nu03TUDihydrofolate reductase1.5.1.30.441
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
3ujlA8SAbscisic acid receptor PYL2/0.441
3w0uHPWLactoylglutathione lyase4.4.1.50.441
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.441
4bcsBTNAvidin-related protein 4/5/0.441
4h6pFMNChromate reductase/0.441
4kxjP34Nucleoprotein/0.441
4oicA8SBet v I allergen-like/0.441
4pkl1GHUncharacterized protein/0.441
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.441
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.441
4udaDEXMineralocorticoid receptor/0.441
4wctFADFructosyl amine:oxygen oxidoreductase/0.441
2ycyP32Beta-1 adrenergic receptor/0.441
1bzmMZMCarbonic anhydrase 14.2.1.10.440
1e3kR18Progesterone receptor/0.440
1gaxVAAValine--tRNA ligase6.1.1.90.440
1h22E10Acetylcholinesterase3.1.1.70.440
1nceCB3Thymidylate synthase/0.440
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.440
1qzyTDEMethionine aminopeptidase 2/0.440
1vrqFONSubunit alpha of sarocosine oxidase/0.440
1wsvTHHAminomethyltransferase, mitochondrial/0.440
2b3vACODiamine acetyltransferase 1/0.440
2g226IGRenin3.4.23.150.440
2hl0A3SThreonine--tRNA ligase6.1.1.30.440
2jblSMAReaction center protein L chain/0.440
2mt9FMNFlavodoxin 2/0.440
2nq8ZIDEnoyl-ACP reductase/0.440
2qimZEAClass 10 plant pathogenesis-related protein/0.440
2vaxCSCAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.440
2vkeTACTetracycline repressor protein class D/0.440
2w3wVG9Dihydrofolate reductase/0.440
2watCOAFatty acid synthase subunit alpha2.3.1.860.440
3gyf51PDihydrofolate reductase1.5.1.30.440
3oadLPORenin3.4.23.150.440
3q44D50M1 family aminopeptidase3.4.110.440
3sp9IL2Peroxisome proliferator-activated receptor delta/0.440
3tfn2CJDehydrosqualene synthase/0.440
4at5MUJBDNF/NT-3 growth factors receptor2.7.10.10.440
4bvnP32Beta-1 adrenergic receptor/0.440
4em9TCEPeroxisome proliferator-activated receptor gamma/0.440
4equG6ISerine/threonine-protein kinase 102.7.11.10.440
4g1z0VPVitamin D3 receptor A/0.440
4gd9BTNStreptavidin/0.440
4gdaBTNStreptavidin/0.440
4jnc1LFBifunctional epoxide hydrolase 23.1.3.760.440
4x5gFOLDihydrofolate reductase1.5.1.30.440
5eyuNADBetaine-aldehyde dehydrogenase/0.440
5k8bPDG8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase/0.440
5kf2COAPredicted acetyltransferase/0.440