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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3tgs03GEnvelope glycoprotein gp160

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
3tgs03GEnvelope glycoprotein gp160/1.000
4i531C1Envelope glycoprotein gp160/0.611
4dko0LMEnvelope glycoprotein gp160/0.588
4dkp0LLEnvelope glycoprotein gp160/0.582
4i541C1Envelope glycoprotein gp160/0.580
4dku0KUEnvelope glycoprotein gp160/0.563
4dvv0M1Envelope glycoprotein gp160/0.548
4dkv0KWEnvelope glycoprotein gp160/0.521
5ex0SAHHistone-lysine N-methyltransferase SMYD32.1.1.430.520
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.503
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.501
1u3wFXYAlcohol dehydrogenase 1C1.1.1.10.500
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.500
3gi3B10Mitogen-activated protein kinase 14/0.497
3mt817TGlycogen phosphorylase, muscle form2.4.1.10.497
1tdrMTXDihydrofolate reductase1.5.1.30.496
2p5uNADUDP-glucose 4-epimerase/0.495
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.494
4kwcSAHMethyltransferase domain family/0.493
2ed3SAHDiphthine synthase/0.492
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.492
1jbpADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
2yy7NADL-threonine dehydrogenase/0.489
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.489
3u9eCOALmo1369 protein/0.489
2pg0FADAcyl-CoA dehydrogenase/0.488
3lbfSAHProtein-L-isoaspartate O-methyltransferase2.1.1.770.487
3pdnSFGHistone-lysine N-methyltransferase SMYD32.1.1.430.486
1p0hACOMycothiol acetyltransferase2.3.1.1890.485
2ejjSAHDiphthine synthase/0.485
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.485
4imfSI3N-acetylneuraminate lyase/0.485
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.484
2j5xGSPADP-ribosylation factor 6/0.484
1lf3EH5Plasmepsin-23.4.23.390.483
3bx5304Mitogen-activated protein kinase 14/0.483
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.481
3g1lRF2HTH-type transcriptional regulator EthR/0.481
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.481
4fflADPUncharacterized protein/0.481
2a94AP0L-lactate dehydrogenase1.1.1.270.480
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.480
4lz81YXGlutamate receptor 2/0.480
1in5ADPHolliday junction ATP-dependent DNA helicase RuvB/0.479
4dw60MNHTH-type transcriptional regulator EthR/0.479
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.478
1t87CAMCamphor 5-monooxygenase1.14.15.10.478
3e01PZ2Gag-Pol polyprotein2.7.7.490.478
1me6IVSPlasmepsin-23.4.23.390.477
1z7yAA5Cysteine synthase 12.5.1.470.477
3kjm245Cytokinin dehydrogenase 11.5.99.120.477
3mdmFJZCholesterol 24-hydroxylase/0.477
1dz4CAMCamphor 5-monooxygenase1.14.15.10.476
1h65GDPTranslocase of chloroplast 343.6.50.476
1omoNADAlanine dehydrogenase/0.476
3iok1P6Tyrosine-protein kinase JAK2/0.476
1dliUDXUDP-glucose 6-dehydrogenase/0.475
2fznFADBifunctional protein PutA1.5.5.20.475
2rh9IGPTryptophan synthase alpha chain/0.475
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
3ukuC69Actin-related protein 3/0.475
4deg0JJHepatocyte growth factor receptor2.7.10.10.475
4l4eCAMCamphor 5-monooxygenase1.14.15.10.475
4ys22BAUncharacterized protein/0.475
1t85CAMCamphor 5-monooxygenase1.14.15.10.474
3q43D66M1 family aminopeptidase3.4.110.474
3zh8C58Protein kinase C iota type2.7.11.130.474
1jscTPPAcetolactate synthase catalytic subunit, mitochondrial2.2.1.60.473
1ky4NADAdenosylhomocysteinase3.3.1.10.473
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2b4yAPRNAD-dependent protein deacylase sirtuin-5, mitochondrial/0.473
3gonANPPhosphomevalonate kinase/0.473
4ck2NVUIntegrase/0.473
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
1phhFADp-hydroxybenzoate hydroxylase/0.472
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
3cppCAMCamphor 5-monooxygenase1.14.15.10.472
3dxmN24Actin-related protein 3/0.472
4cggK5QIntegrase/0.472
4dpeNGHStromelysin-13.4.24.170.472
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.472
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.472
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.471
2bkzSBCCyclin-dependent kinase 22.7.11.220.471
2ohvNHLGlutamate racemase/0.471
3d7zGK5Mitogen-activated protein kinase 14/0.471
3fwgCAMCamphor 5-monooxygenase1.14.15.10.471
3own3OXRenin3.4.23.150.471
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.471
4kin1M8Mitogen-activated protein kinase 14/0.471
1nzdUPGDNA beta-glucosyltransferase/0.470
2v13C40Renin3.4.23.150.470
3fpzAHZThiamine thiazole synthase/0.470
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.470
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.470
2egsSAHDiphthine synthase/0.469
2przOMPOrotate phosphoribosyltransferase 12.4.2.100.469
3phiNDPShikimate dehydrogenase (NADP(+))/0.469
4kvzSAHPtnL protein/0.469
3sn6P0GBeta-2 adrenergic receptor/0.469
1b14NADAlcohol dehydrogenase1.1.1.10.468
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.468
1u33LM2Pancreatic alpha-amylase/0.468
2d4h5GPGuanylate-binding protein 1/0.468
2o2sTCLEnoyl-acyl carrier reductase/0.468
2qrqS13Glycogen phosphorylase, muscle form2.4.1.10.468
3fwjCAMCamphor 5-monooxygenase1.14.15.10.468
3itzP66Mitogen-activated protein kinase 14/0.468
3s7dLEU_SER_LYS_LYS_MLZN-lysine methyltransferase SMYD2/0.468
4acm7YGCyclin-dependent kinase 22.7.11.220.468
4ng5PFBAlcohol dehydrogenase E chain1.1.1.10.468
1s7nCOAAcetyl transferase/0.467
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
3b8z294A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.467
3d5fL41Peroxisome proliferator-activated receptor delta/0.467
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
4kb81QOCasein kinase I isoform delta2.7.11.10.467
5hq8SAHHistone-lysine N-methyltransferase SMYD32.1.1.430.467
1f4eTPRThymidylate synthase/0.466
1kfcIPLTryptophan synthase alpha chain/0.466
1mueCDDProthrombin3.4.21.50.466
1nhtPGSAdenylosuccinate synthetase/0.466
1pqc444Oxysterols receptor LXR-beta/0.466
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.466
2fj1CTCTetracycline repressor protein class D/0.466
2npxNADNADH peroxidase1.11.1.10.466
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.466
3dh0SAMUncharacterized protein/0.466
3lt2FT3Enoyl-ACP reductase/0.466
3t6iNC9Endothiapepsin3.4.23.220.466
4l2oNADAldehyde dehydrogenase, dimeric NADP-preferring/0.466
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.466
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.465
2hpvFMNFMN-dependent NADH-azoreductase1.70.465
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.465
2qn3F55Glycogen phosphorylase, muscle form2.4.1.10.465
2znpK55Peroxisome proliferator-activated receptor delta/0.465
3hyg099A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.465
3oq6PFBAlcohol dehydrogenase E chain1.1.1.10.465
3psyRB9Endothiapepsin3.4.23.220.465
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.465
4lhvGDPRas-related protein Rab-8A/0.465
1kvkATPMevalonate kinase2.7.1.360.464
1l4fNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.464
1rw8580TGF-beta receptor type-12.7.11.300.464
1zp8AB2Protease/0.464
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2uzeC95Cyclin-dependent kinase 22.7.11.220.464
2w71L23Biotin carboxylase6.3.4.140.464
3angDCCTranscriptional repressor, TetR family/0.464
3nx2FERFerulic acid decarboxylase/0.464
4ejmNAPPutative zinc-binding dehydrogenase/0.464
4qxaGTPRas-related protein Rab-9A/0.464
4rvnCOAPhenylacetate-coenzyme A ligase/0.464
6cp4CAMCamphor 5-monooxygenase1.14.15.10.464
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
2qboCAMCamphor 5-monooxygenase1.14.15.10.463
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.463
3friSAH16S rRNA methylase/0.463
4yntFDAGlucose oxidase, putative/0.463
4zvmDM2Ribosyldihydronicotinamide dehydrogenase [quinone]/0.463
1pvgANPDNA topoisomerase 25.99.1.30.462
1u80C5PCoenzyme A biosynthesis bifunctional protein CoaBC6.3.2.50.462
2o2yTCLEnoyl-ACP reductase/0.462
2p2xSAHDiphthine synthase/0.462
3fwfCAMCamphor 5-monooxygenase1.14.15.10.462
3l63CAMCamphor 5-monooxygenase1.14.15.10.462
4bb3KKAIsopenicillin N synthase1.21.3.10.462
4qbiAP5Adenylate kinase/0.462
4rvoADPPhenylacetate-coenzyme A ligase/0.462
4yv1S4MSpermidine synthase, putative/0.462
4zs2FLUAlpha-ketoglutarate-dependent dioxygenase FTO/0.462
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.462
1txtCAAHMG-CoA synthase/0.461
2bn4FADNADPH--cytochrome P450 reductase/0.461
2he5NDPAldo-keto reductase family 1 member C211.1.10.461
2ih2NEAModification methylase TaqI2.1.1.720.461
2ji9ADPOxalyl-CoA decarboxylase4.1.1.80.461
2pckSAHDiphthine synthase/0.461
2rewREWPeroxisome proliferator-activated receptor alpha/0.461
3g1oRF1HTH-type transcriptional regulator EthR/0.461
3o8hO8HHTH-type transcriptional regulator EthR/0.461
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
4c62XWWTyrosine-protein kinase JAK2/0.461
4o4fATPKinase/0.461
4p9dTMPDeoxycytidylate deaminase/0.461
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.461
5e72SAMN2, N2-dimethylguanosine tRNA methyltransferase/0.461
1w2xRCPAcetyl-CoA carboxylase/0.460
1z0uNAPNAD kinase/0.460
2e4nSAHDiphthine synthase/0.460
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.460
2v58LZJBiotin carboxylase6.3.4.140.460
3dejRXCCaspase-33.4.22.560.460
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.460
3tnwF18Cyclin-dependent kinase 22.7.11.220.460
4ap7F47Hepatocyte growth factor receptor2.7.10.10.460
4kgkGTPUncharacterized protein/0.460
5htxADPPutative xylulose kinase/0.460
4zj8SUVOrexin receptor type 1/0.460
1ia1NDPDihydrofolate reductase1.5.1.30.459
1pq944BOxysterols receptor LXR-beta/0.459
1ra3MTXDihydrofolate reductase1.5.1.30.459
2c6kDT2Cyclin-dependent kinase 22.7.11.220.459
2g82NADGlyceraldehyde-3-phosphate dehydrogenase/0.459
2j62GSZO-GlcNAcase NagJ/0.459
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.459
2zulSAMProbable ribosomal RNA small subunit methyltransferase/0.459
3crzFADFerredoxin--NADP+ reductase/0.459
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3f7bAG5Carbonic anhydrase 44.2.1.10.459
3fhxPLPPyridoxal kinase2.7.1.350.459
3mykBITMyosin-2 heavy chain/0.459
3ppr4CSGlycine betaine/carnitine/choline-binding protein OpuCC/0.459
3tg4SAMN-lysine methyltransferase SMYD2/0.459
3tzaTZGGlutamate receptor 2/0.459
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.459
4uirFADOleate hydratase4.2.1.530.459
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.458
1lkeDOGBilin-binding protein/0.458
1t86CAMCamphor 5-monooxygenase1.14.15.10.458
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.458
2c6tDT5Cyclin-dependent kinase 22.7.11.220.458
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.458
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3tlh3TLGag-Pol polyprotein3.4.23.160.458
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.458
4j361HRKynurenine 3-monooxygenase/0.458
4xj43ATCyclic GMP-AMP synthase/0.458
4y380A9Endothiapepsin3.4.23.220.458
5cdgPFBAlcohol dehydrogenase E chain1.1.1.10.458
1tkaN3TTransketolase 12.2.1.10.457
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
2h94FADLysine-specific histone demethylase 1A10.457
2op18PCEnoyl-ACP reductase/0.457
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.457
2v3aFADRubredoxin-NAD(+) reductase1.18.1.10.457
2vkvTDCTetracycline repressor protein class D/0.457
2wedPP6Penicillopepsin-13.4.23.200.457
3g2lLEWGlycogen phosphorylase, muscle form2.4.1.10.457
3n0hTOPDihydrofolate reductase1.5.1.30.457
3rn8RN8Glutamate receptor 2/0.457
3wrjCAMCamphor 5-monooxygenase1.14.15.10.457
4ek1CAMCamphor 5-monooxygenase1.14.15.10.457
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.457
4xulGTPUncharacterized protein mg662/0.457
5d4uSAMUncharacterized protein MJ0489/0.457
1a71NADAlcohol dehydrogenase E chain1.1.1.10.456
1ey3DAKEnoyl-CoA hydratase, mitochondrial4.2.1.170.456
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
1tqf32PBeta-secretase 13.4.23.460.456
2d32ANPGlutamate--cysteine ligase6.3.2.20.456
2hfuMEVMevalonate kinase/0.456
2hvdADPNucleoside diphosphate kinase A2.7.4.60.456
2r9eSDXCitrate synthase2.3.3.160.456
2vr1ATFBiotin carboxylase6.3.4.140.456
2zuiCAMCamphor 5-monooxygenase1.14.15.10.456
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.456
3kry3KRCollagenase 33.4.240.456
4da8BG2Purine nucleoside phosphorylase DeoD-type2.4.2.10.456
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
4oztP1AEcdysone receptor, putative/0.456
1e2nRCAThymidine kinase/0.455
1l4lNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.455
1mv8GDXGDP-mannose 6-dehydrogenase1.1.1.1320.455
1o76CAMCamphor 5-monooxygenase1.14.15.10.455
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.455
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.455
2egbSAHDiphthine synthase/0.455
2qbmCAMCamphor 5-monooxygenase1.14.15.10.455
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.455
2vbpVB1Isopenicillin N synthase1.21.3.10.455
2vv9IM9Cyclin-dependent kinase 22.7.11.220.455
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.455
3am3TCLEnoyl-ACP reductase/0.455
3arvSAUChitinase A/0.455
3bptQUE3-hydroxyisobutyryl-CoA hydrolase, mitochondrial3.1.2.40.455
3cgbCOACoenzyme A disulfide reductase/0.455
3tjsD0RCytochrome P450 3A4/0.455
3up0D7SaceDAF-12/0.455
3v9y24LPeroxisome proliferator-activated receptor gamma/0.455
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.455
4nmbFADBifunctional protein PutA/0.455
4y35F90Endothiapepsin3.4.23.220.455
4zlgLGCPutative b-glycan phosphorylase/0.455
5agaANPDNA polymerase theta/0.455
1hxbROCGag-Pol polyprotein3.4.23.160.454
1uxuNAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase/0.454
2c6o4SPCyclin-dependent kinase 22.7.11.220.454
2e8rSAHDiphthine synthase/0.454
2eh4SAHDiphthine synthase/0.454
2ejzSAHDiphthine synthase/0.454
2gilGTPRas-related protein Rab-6A/0.454
2ovhAS0Progesterone receptor/0.454
2pa7TYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.454
3btoSSBAlcohol dehydrogenase E chain1.1.1.10.454
3eksCY9Actin-5C/0.454
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
3iidAPRCore histone macro-H2A.1/0.454
3lxiCAMCytochrome P450/0.454
3oxfSAHHistone-lysine N-methyltransferase SMYD32.1.1.430.454
3r3sNADPutative oxidoreductase/0.454
3vg9ZMAAdenosine receptor A2a/0.454
4bj9UHBTankyrase-22.4.2.300.454
4hvg19QTyrosine-protein kinase JAK32.7.10.20.454
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.454
4ja1NGHStromelysin-13.4.24.170.454
4xd1T3QQdtf/0.454
5cdtPFBAlcohol dehydrogenase E chain1.1.1.10.454
1n83CLRNuclear receptor ROR-alpha/0.453
1rx7FOLDihydrofolate reductase1.5.1.30.453
2az83TLGag-Pol polyprotein3.4.23.160.453
2bm9SAMCephalosporin hydroxylase CmcI/0.453
2cvjFADThioredoxin reductase related protein/0.453
2e07SAHDiphthine synthase/0.453
2nuaCOASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.453
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.453
2r8oT5XTransketolase 1/0.453
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2v59LZKBiotin carboxylase6.3.4.140.453
2webPP4Penicillopepsin-13.4.23.200.453
3ajrNADNDP-sugar epimerase/0.453
3b7dCNIGlutamate receptor 2/0.453
3nhfVVVRibosyldihydronicotinamide dehydrogenase [quinone]/0.453
3owyEQUSteroid Delta-isomerase5.3.3.10.453
3pndFADFAD:protein FMN transferase/0.453
3rimTPPTransketolase2.2.1.10.453
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.453
4kiq1RAMitogen-activated protein kinase 14/0.453
4mv8ACPBiotin carboxylase6.3.4.140.453
4y8wSTRSteroid 21-hydroxylase/0.453
1bsvNDPGDP-L-fucose synthase/0.452
1d8mBBHStromelysin-13.4.24.170.452
1dnpMHFDeoxyribodipyrimidine photo-lyase4.1.99.30.452
1dq8COA3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.452
1g2vTTPGlucose-1-phosphate thymidylyltransferase/0.452
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.452
2ewnBTXBifunctional ligase/repressor BirA/0.452
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.452
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.452
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.452
2oapANPType II secretion system protein (GspE-2)/0.452
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.452
2xa4AZ5Tyrosine-protein kinase JAK2/0.452
3bmqAX5Pteridine reductase/0.452
3bv3P39Mitogen-activated protein kinase 14/0.452
3f4bTCLEnoyl-acyl carrier protein reductase/0.452
3ft8MOJHeat shock protein HSP 90-alpha/0.452
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.452
3o8gO8GHTH-type transcriptional regulator EthR/0.452
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.452
3wrhCAMCamphor 5-monooxygenase1.14.15.10.452
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.452
4dptAGSMevalonate diphosphate decarboxylase/0.452
4ifn12OKelch-like ECH-associated protein 1/0.452
4jqeANPCasein kinase II subunit alpha2.7.11.10.452
4la7A1OAbscisic acid receptor PYL2/0.452
4q0kGA3Phytohormone-binding protein/0.452
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.452
4ymvATPABC-type polar amino acid transport system, ATPase component/0.452
1a8pFADFerredoxin--NADP reductase/0.451
1lf2R37Plasmepsin-23.4.23.390.451
1orhSAHProtein arginine N-methyltransferase 1/0.451
1pd9CO4Dihydrofolate reductase1.5.1.30.451
1x0pFADTll0078 protein/0.451
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
2bxtC2DProthrombin3.4.21.50.451
2c27ACOMycothiol acetyltransferase2.3.1.1890.451
2cndFADNitrate reductase [NADH]1.7.1.10.451
2ftoCB3Thymidylate synthase/0.451
2ibuCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.451
3c36KAIGlutamate receptor ionotropic, kainate 1/0.451
3cnpSP7Polyamine oxidase FMS1/0.451
3gviADPMalate dehydrogenase/0.451
3ii43IIDihydrolipoyl dehydrogenase1.8.1.40.451
3v4aPK1Androgen receptor/0.451
4b6uM7GEukaryotic translation initiation factor 4E type 3/0.451
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4e32DWNMethyltransferase/0.451
4l49CAMCamphor 5-monooxygenase1.14.15.10.451
4uyg73BBromodomain-containing protein 2/0.451
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.451
1b3rNADAdenosylhomocysteinase3.3.1.10.450
2ci01CMLanosterol 14-alpha demethylase1.14.13.700.450
2dshSAHDiphthine synthase/0.450
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.450
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.450
2fhnBNIAvidin-related protein 4/5/0.450
2ibwCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.450
2ohjFMNType A flavoprotein FprA10.450
2uzfCAA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.450
2xabVHDHeat shock protein HSP 90-alpha/0.450
2y5kYCUFructose-1,6-bisphosphatase 13.1.3.110.450
3deiRXBCaspase-33.4.22.560.450
3e8xNAPBH1520 protein/0.450
3iltTRUGlutamate receptor 2/0.450
3mdvCL6Cholesterol 24-hydroxylase/0.450
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.450
3n0tOPYDipeptidyl peptidase 23.4.14.20.450
3r9uFADThioredoxin reductase/0.450
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.450
4bmoFMNProtein NrdI/0.450
4c717RD3-oxoacyl-ACP synthase/0.450
4dpi0N1Beta-secretase 13.4.23.460.450
4gqlR47Macrophage metalloelastase3.4.24.650.450
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
4ma628EAra h 8 allergen/0.450
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.450
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.450
5e8wSTUTGF-beta receptor type-12.7.11.300.450
4djhJDCKappa-type opioid receptor/0.450
1f20FADNitric oxide synthase, brain1.14.13.390.449
1v59FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.449
1vpmCOAAcyl-CoA hydrolase/0.449
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2bbwGP5Adenylate kinase 4, mitochondrial/0.449
2g9rG27Glycogen phosphorylase, muscle form2.4.1.10.449
2i51FMNPyridoxamine 5'-phosphate oxidase-related, FMN-binding/0.449
2nyuSAMrRNA methyltransferase 2, mitochondrial/0.449
2qi0MZ3Gag-Pol polyprotein/0.449
2vcmM11Isopenicillin N synthase1.21.3.10.449
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.449
2wu4HBPAcetylcholinesterase3.1.1.70.449
2ylsFADPhenylacetone monooxygenase1.14.13.920.449
3dmhSAMProbable ribosomal RNA small subunit methyltransferase/0.449
3ixp834Ecdysone receptor/0.449
3pftFMNFlavin reductase/0.449
3r9oZ71Cyclin-dependent kinase 22.7.11.220.449
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
4a99FADTetX family tetracycline inactivation enzyme/0.449
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.449
4e2wJHZMethyltransferase/0.449
4i8qNADPutative betaine aldehyde dehyrogenase/0.449
4kkyCAMCamphor 5-monooxygenase1.14.15.10.449
4pnmNU1Tankyrase-22.4.2.300.449
4twnB96Ephrin type-A receptor 32.7.10.10.449
4yvjSFGtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.449
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.449
5hs1VORLanosterol 14-alpha demethylase/0.449
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.448
1d6w00RProthrombin3.4.21.50.448
1hfqMOTDihydrofolate reductase1.5.1.30.448
1hv5RXPStromelysin-33.4.240.448
1k7fIAVTryptophan synthase alpha chain/0.448
1pg3PRXAcetyl-coenzyme A synthetase/0.448
1qvnFRIInterleukin-2/0.448
2acxANPG protein-coupled receptor kinase 62.7.11.160.448
2fhiIB2Bis(5'-adenosyl)-triphosphatase3.6.1.290.448
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.448
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.448
2q5g1FAPeroxisome proliferator-activated receptor delta/0.448
2qblCAMCamphor 5-monooxygenase1.14.15.10.448
2vetUMPThymidylate synthase/0.448
2yqzSAMUncharacterized protein/0.448
2z71PNVPenicillin acylase3.5.1.110.448
3cgcCOACoenzyme A disulfide reductase/0.448
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3juoAJDPhenazine biosynthesis protein A/B/0.448
3w3zGTPGTP-binding nuclear protein Ran/0.448
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.448
3zmmF9JTyrosine-protein kinase JAK2/0.448
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.448
4at0FADPossible succinate dehydrogenase/0.448
4ceqQCHIntegrase/0.448
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4iwd1JCHepatocyte growth factor receptor2.7.10.10.448
4kugNAD3-hydroxybutyryl-CoA dehydrogenase/0.448
4loqSB4Mitogen-activated protein kinase 14/0.448
4y7cFMNNADPH--cytochrome P450 reductase/0.448
4zqcF6FTryptophan synthase alpha chain/0.448
5kf8ACOPredicted acetyltransferase/0.448
1b16NAQAlcohol dehydrogenase1.1.1.10.447
1biwS80Stromelysin-13.4.24.170.447
1c1dNAIPhenylalanine dehydrogenase/0.447
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1gj5130Prothrombin3.4.21.50.447
1qjfACSIsopenicillin N synthase1.21.3.10.447
1rdt570Peroxisome proliferator-activated receptor gamma/0.447
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2a1nCAMCamphor 5-monooxygenase1.14.15.10.447
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
2csnCKICasein kinase I homolog 12.7.11.10.447
2feuCAMCamphor 5-monooxygenase1.14.15.10.447
2g1a5HGClass B acid phosphatase3.1.3.20.447
2huvSAHDiphthine synthase/0.447
2kmnBB2Peptide deformylase3.5.1.880.447
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.447
2p0rLEU_LEU_ACE_AR7Calpain-9/0.447
2p6iSAHDiphthine synthase/0.447
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.447
2znq401Peroxisome proliferator-activated receptor delta/0.447
3a7dFBNCatechol O-methyltransferase2.1.1.60.447
3egvSAHRibosomal protein L11 methyltransferase2.1.10.447
3fz1B98Cyclin-dependent kinase 22.7.11.220.447
3i53SAH2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase/0.447
3mvl38PMitogen-activated protein kinase 14/0.447
3rvg17PTyrosine-protein kinase JAK2/0.447
3sf6FDAGlutaryl-CoA dehydrogenase/0.447
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.447
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.447
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
4b754VAGenome polyprotein3.4.21.980.447
4btmF8ETau-tubulin kinase 12.7.11.10.447
4c2jCOA3-ketoacyl-CoA thiolase, mitochondrial2.3.1.160.447
4fk8FADFerredoxin--NADP reductase/0.447
4g1nNZTPyruvate kinase PKM2.7.1.400.447
4jx1CAHCamphor 5-monooxygenase1.14.15.10.447
4l82FMNUncharacterized protein/0.447
4lj6ACPChaperone protein ClpB/0.447
4u7tSAHDNA (cytosine-5)-methyltransferase 3A2.1.1.370.447
4xybNDPFormate dehydrogenase/0.447
5kj1PFBAlcohol dehydrogenase E chain1.1.1.10.447
1efaNPFLactose operon repressor/0.446
1g63FMNEpidermin decarboxylase4.1.10.446
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.446
1k5dGNPGTP-binding nuclear protein Ran/0.446
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
1rz0FADPhenol 2-hydroxylase component B/0.446
1xelUPGUDP-glucose 4-epimerase5.1.3.20.446
1zrcCMPcAMP-activated global transcriptional regulator CRP/0.446
2b53D23Cyclin-dependent kinase 22.7.11.220.446
2eldSAHDiphthine synthase/0.446
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
2v7qADPATP synthase subunit beta, mitochondrial3.6.3.140.446
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.446
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.446
3lsmSFDPyranose 2-oxidase/0.446
3nhwZXZRibosyldihydronicotinamide dehydrogenase [quinone]/0.446
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.446
3pxkPXKFocal adhesion kinase 12.7.10.20.446
3q60ATPRhoptry protein 5B/0.446
3rouCMPcAMP-activated global transcriptional regulator CRP/0.446
3uleC69Actin-related protein 3/0.446
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.446
4bcsBTNAvidin-related protein 4/5/0.446
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
4cerVL4Integrase/0.446
4eueNAITrans-2-enoyl-CoA reductase [NADH]/0.446
4f081RSTyrosine-protein kinase JAK2/0.446
4fhd0TTSpore photoproduct lyase/0.446
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.446
4l4dCAMCamphor 5-monooxygenase1.14.15.10.446
4nc3ERM5-hydroxytryptamine receptor 2B/0.446
4qmySTUSerine/threonine-protein kinase 242.7.11.10.446
4rcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.446
4yaf2AMNADPH--cytochrome P450 reductase/0.446
4ycpFMNtRNA-dihydrouridine(16) synthase/0.446
4yusFMNFamily 3 adenylate cyclase/0.446
5d4vSAHUncharacterized protein MJ0489/0.446
5fm7ADPRuvB-like helicase/0.446
6adhNADAlcohol dehydrogenase E chain1.1.1.10.446
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1iy8NADLevodione reductase/0.445
1k08BZDGlycogen phosphorylase, muscle form2.4.1.10.445
1mrxK57Gag-Pol polyprotein3.4.23.160.445
1nbiSAMGlycine N-methyltransferase2.1.1.200.445
1nooCAHCamphor 5-monooxygenase1.14.15.10.445
1pt5ACOFormyl-CoA:oxalate CoA-transferase/0.445
1qiwDPDCalmodulin/0.445
1qw5H4BNitric oxide synthase, inducible1.14.13.390.445
1t3r017Gag-Pol polyprotein3.4.23.160.445
1wklATPNucleoside diphosphate kinase/0.445
2c31ADPOxalyl-CoA decarboxylase4.1.1.80.445
2cjiGSKCoagulation factor X3.4.21.60.445
2givACOHistone acetyltransferase KAT8/0.445
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2i7pACOPantothenate kinase 32.7.1.330.445
2iw84SPCyclin-dependent kinase 22.7.11.220.445
2pulACPMethylthioribose kinase2.7.1.1000.445
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2zwaSAHtRNA wybutosine-synthesizing protein 42.1.1.2900.445
2zwvSAHProbable ribosomal RNA small subunit methyltransferase/0.445
3gphOIDCytochrome P450 2E11.14.130.445
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.445
3lxkMI1Tyrosine-protein kinase JAK32.7.10.20.445
3oiiSAHRibosomal RNA small subunit methyltransferase NEP1/0.445
3owsEQUSteroid Delta-isomerase5.3.3.10.445
3qwc98PProthrombin3.4.21.50.445
3zcsCAWGlycogen phosphorylase, muscle form2.4.1.10.445
4ap3FADSteroid monooxygenase/0.445
4blvSAMRibosomal RNA large subunit methyltransferase J/0.445
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.445
4dqb017Gag-Pol polyprotein/0.445
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
5cb4ACPTubulin tyrosine ligase/0.445
5eccNAPDehydrofolate reductase type I/0.445
5fwnNAPPutative dehydrogenase/0.445
5kjePFBAlcohol dehydrogenase E chain1.1.1.10.445
6ctsCICCitrate synthase, mitochondrial2.3.3.10.445
6tmn0PIThermolysin3.4.24.270.445
1e2kTMCThymidine kinase/0.444
1ef3NAPAldose reductase1.1.1.210.444
1esqTZPHydroxyethylthiazole kinase/0.444
1h73ANPHomoserine kinase2.7.1.390.444
1jhaAAMNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.444
1kh3ANPArgininosuccinate synthase/0.444
1kkq471Peroxisome proliferator-activated receptor alpha/0.444
1ot3THMDeoxynucleoside kinase/0.444
1qrrUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.444
1sxjAGSReplication factor C subunit 1/0.444
1xb1ALA_VAL_PRO_ILE_ALABaculoviral IAP repeat-containing protein 8/0.444
1yhjR6CPyridoxal kinase2.7.1.350.444
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.444
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.444
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.444
2b8tTHMThymidine kinase/0.444
2ewvADPTwitching motility protein PilT/0.444
2ftoTMPThymidylate synthase/0.444
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.444
2h12CMXCitrate synthase/0.444
2hk9NAPShikimate dehydrogenase (NADP(+))/0.444
2rc4ACOHistone acetyltransferase KAT6A/0.444
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.444
2zbaZBATrichothecene 3-O-acetyltransferase/0.444
2zevB71Geranylgeranyl pyrophosphate synthase/0.444
3k5dXLIBeta-secretase 13.4.23.460.444
3ndjJHZMethyltransferase/0.444
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
3p0hFSEPutative tyrosyl-tRNA synthetase/0.444
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
3uph0C1Genome polyprotein2.7.7.480.444
3uwlFOZThymidylate synthase/0.444
3uylTYDProbable NDP-rhamnosyltransferase/0.444
4agoP74Cellular tumor antigen p53/0.444
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.444
4b8zNAPGDP-L-fucose synthase1.1.1.2710.444
4btkDTQTau-tubulin kinase 12.7.11.10.444
4eqwCOACoenzyme A disulfide reductase/0.444
4f700STCyclin-dependent kinase 82.7.11.220.444
4iqqUMPThymidylate synthase/0.444
4jtrIZPAldo-keto reductase family 1 member C2/0.444
4n4v2GYTankyrase-12.4.2.300.444
4u7wNDPMxaA/0.444
4v2gCTCTetracycline repressor protein class D/0.444
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.444
5ax35IDMitogen-activated protein kinase 12.7.11.240.444
5bxySAHPutative RNA methylase family UPF0020/0.444
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
1aj8COACitrate synthase/0.443
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.443
1hk5T44Serum albumin/0.443
1hmp5GPHypoxanthine-guanine phosphoribosyltransferase2.4.2.80.443
1ig0VIBThiamine pyrophosphokinase2.7.6.20.443
1mmaADPMyosin-2 heavy chain/0.443
1u3dFADCryptochrome-1/0.443
1uyuCAMCamphor 5-monooxygenase1.14.15.10.443
1v0oINRCell division control protein 2 homolog2.7.11.220.443
1xe65FPPlasmepsin-23.4.23.390.443
1zgv501Prothrombin3.4.21.50.443
2bycFMNBlue-light receptor of the BLUF-family/0.443
2cvuCDPRibonucleoside-diphosphate reductase large chain 11.17.4.10.443
2dv7SAHDiphthine synthase/0.443
2hekGDPUncharacterized protein/0.443
2hm1LIQBeta-secretase 13.4.23.460.443
2ow9SP6Collagenase 33.4.240.443
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.443
2qk8MTXDihydrofolate reductase/0.443
2r1rTTPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.443
2uxhQUEHTH-type transcriptional regulator TtgR/0.443
2uzlC94Cyclin-dependent kinase 22.7.11.220.443
2wi5ZZ5Heat shock protein HSP 90-alpha/0.443
2woa576Macrophage metalloelastase3.4.24.650.443
2wqoVGKSerine/threonine-protein kinase Nek22.7.11.10.443
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.443
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.443
3eljGS7Mitogen-activated protein kinase 82.7.11.240.443
3gqoAPRNon-structural polyprotein/0.443
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.443
3kfr3TLGag-Pol polyprotein/0.443
3nwxKVSGag-Pol polyprotein3.4.23.160.443
3och2MXDihydrofolate reductase1.5.1.30.443
3pyy3YYTyrosine-protein kinase ABL12.7.10.20.443
3qbwADPAnhydro-N-acetylmuramic acid kinase/0.443
3qt62P0Mevalonate diphosphate decarboxylase/0.443
3s1dZIRCytokinin dehydrogenase 11.5.99.120.443
3tz3B36Acetyl-CoA carboxylase/0.443
3u8n09SAcetylcholine-binding protein/0.443
3zpqXF5Beta-1 adrenergic receptor/0.443
4c02TAKActivin receptor type-12.7.11.300.443
4el0D1KGlycogen phosphorylase, muscle form2.4.1.10.443
4ew2DXYTrifunctional purine biosynthetic protein adenosine-32.1.2.20.443
4fse0VABeta-secretase 13.4.23.460.443
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.443
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.443
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.443
4nj32KDCyclin-dependent kinase 22.7.11.220.443
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.443
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.443
5kf1ACOPredicted acetyltransferase/0.443
1ad3NADAldehyde dehydrogenase, dimeric NADP-preferring/0.442
1bc5SAHChemotaxis protein methyltransferase2.1.1.800.442
1bcpATPPertussis toxin subunit 4/0.442
1bcpATPPertussis toxin subunit 5/0.442
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1gebCAMCamphor 5-monooxygenase1.14.15.10.442
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.442
1m9aGTXGlutathione S-transferase class-mu 26 kDa isozyme2.5.1.180.442
1ny2ARG_PRO_PRO_GLYProthrombin3.4.21.50.442
1twwHH2Dihydropteroate synthase/0.442
1uh5TCLEnoyl-ACP reductase/0.442
1uumFMNDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.442
1y9dTPPPyruvate oxidase1.2.3.30.442
2ag0TPPBenzaldehyde lyase/0.442
2b3dFADModulator of drug activity B/0.442
2bunFADAppA protein/0.442
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.442
2eniSAHDiphthine synthase/0.442
2g1n1IGRenin3.4.23.150.442
2g7mAN0Ornithine carbamoyltransferase/0.442
2hp2KE4Glutamate-1-semialdehyde 2,1-aminomutase5.4.3.80.442
2ij7TPFMycocyclosin synthase1.14.21.90.442
2j4kU5PUridylate kinase2.7.4.220.442
2q3eNAIUDP-glucose 6-dehydrogenase1.1.1.220.442
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.442
2xlrFADPutative flavin-containing monooxygenase/0.442
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.442
3bheBZNGag-Pol polyprotein3.4.23.160.442
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.442
3e92G6AMitogen-activated protein kinase 14/0.442
3fklFKLMitogen-activated protein kinase 14/0.442
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.442
3m12FADMonomeric sarcosine oxidase1.5.3.10.442
3p3zP3ZPutative cytochrome P450/0.442
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.442
4b45GSPTubulin-like protein CetZ2/0.442
4b5dSW4Achbp/0.442
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4cf1IY7Integrase/0.442
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.442
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.442
4kb81QNCasein kinase I isoform delta2.7.11.10.442
4o6fSAHN-lysine methyltransferase SMYD2/0.442
4qmpDKISerine/threonine-protein kinase 242.7.11.10.442
4qnaX11Serine/threonine-protein kinase 242.7.11.10.442
4r4uCOAAcyl-CoA thioesterase II/0.442
4xugF9FTryptophan synthase alpha chain/0.442
5es7FONLinear gramicidin synthase subunit A/0.442
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.441
1dz6CAMCamphor 5-monooxygenase1.14.15.10.441
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.441
1ixeCOACitrate synthase/0.441
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.441
1p0pBCHCholinesterase3.1.1.80.441
1py5PY1TGF-beta receptor type-12.7.11.300.441
1r00SAHAclacinomycin 10-hydroxylase RdmB4.1.10.441
1sg9SAMRelease factor glutamine methyltransferase2.1.1.2970.441
1tj2FADBifunctional protein PutA1.5.5.20.441
1upw444Oxysterols receptor LXR-beta/0.441
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.441
1xzqFONtRNA modification GTPase MnmE3.6.50.441
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.441
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.441
2i40BLZCyclin-dependent kinase 22.7.11.220.441
2izuP01Casein kinase I isoform gamma-32.7.11.10.441
2k62ITLFatty acid-binding protein, liver/0.441
2p5cSAHDiphthine synthase/0.441
2panFADGlyoxylate carboligase4.1.1.470.441
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.441
2pivDHTAndrogen receptor/0.441
2v5vFMNFlavodoxin/0.441
2vmyFFOSerine hydroxymethyltransferase/0.441
2y3rTRKTamL/0.441
2yj4ATPCopper-transporting ATPase/0.441
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3fql79ZGenome polyprotein2.7.7.480.441
3hz5Z64Heat shock protein HSP 90-alpha/0.441
3lixE17Protease/0.441
3mtfA3FActivin receptor type-12.7.11.300.441
3nhpHGZRibosyldihydronicotinamide dehydrogenase [quinone]/0.441
3o3pGDDGlycosyl transferase, family 2/0.441
3pt6SAHDNA (cytosine-5)-methyltransferase 12.1.1.370.441
3qj0QI3Botulinum neurotoxin type A3.4.24.690.441
3r7uX96Cyclin-dependent kinase 22.7.11.220.441
3rpeFADPutative modulator of drug activity/0.441
3tskQEGMacrophage metalloelastase3.4.24.650.441
3ubmCOAFormyl-CoA:oxalate CoA-transferase/0.441
3x2uATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4apuA2KProgesterone receptor/0.441
4awq592Heat shock protein HSP 90-alpha/0.441
4cfaWOPIntegrase/0.441
4dvi2IWTankyrase-12.4.2.300.441
4fkt48KCyclin-dependent kinase 22.7.11.220.441
4fqsLYAThymidylate synthase ThyA/0.441
4fx360KCyclin-dependent kinase 22.7.11.220.441
4g6oE28Mitogen-activated protein kinase 12.7.11.240.441
4g95OAGDihydrofolate reductase1.5.1.30.441
4j491J1Uncharacterized protein/0.441
4jubTPPBenzoylformate decarboxylase4.1.1.70.441
4kba1QMCasein kinase I isoform delta2.7.11.10.441
4nk92K5Fibroblast growth factor receptor 1/0.441
4tuvCPZCytochrome P450 1191.140.441
4xzmNAPAldo-keto reductase family 1 member B101.1.10.441
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.441
5epeSAHUncharacterized protein/0.441
5hynSAHHistone-lysine N-methyltransferase EZH22.1.1.430.441
1a8rGTPGTP cyclohydrolase 13.5.4.160.440
1beuIPLTryptophan synthase alpha chain/0.440
1i00D16Thymidylate synthase2.1.1.450.440
1k6mAGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 12.7.1.1050.440
1knuYPAPeroxisome proliferator-activated receptor gamma/0.440
1m9tH4BNitric oxide synthase, inducible1.14.13.390.440
1nhz486Glucocorticoid receptor/0.440
1pzgA3DLactate dehydrogenase/0.440
1u28NAPNAD(P) transhydrogenase subunit beta1.6.1.20.440
1u2yGOXPancreatic alpha-amylase/0.440
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.440
1xkkFMMEpidermal growth factor receptor2.7.10.10.440
2ab8MTPAdenosine kinase2.7.1.200.440
2b69NADUDP-glucuronic acid decarboxylase 14.1.1.350.440
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.440
2c9dPHR6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
2cbrA80Cellular retinoic acid-binding protein 1/0.440
2cjfRP43-dehydroquinate dehydratase4.2.1.100.440
2ctsCOACitrate synthase, mitochondrial2.3.3.10.440
2eufLQQCyclin-dependent kinase 62.7.11.220.440
2io6330Wee1-like protein kinase2.7.10.20.440
2qirCOAAminoglycoside 6-N-acetyltransferase type Ib11/0.440
2rhgIGPTryptophan synthase alpha chain/0.440
2wd9IBPAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.440
2wi2ZZ3Heat shock protein HSP 90-alpha/0.440
2y05NAPProstaglandin reductase 1/0.440
2y3sTIRTamL/0.440
2ym1FADPhenylacetone monooxygenase1.14.13.920.440
2z4y252Geranylgeranyl pyrophosphate synthase/0.440
3f6891UProthrombin3.4.21.50.440
3hk1B64Fatty acid-binding protein, adipocyte/0.440
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.440
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.440
3n4mCMPcAMP-activated global transcriptional regulator CRP/0.440
3qx4X4BCyclin-dependent kinase 22.7.11.220.440
3s8pSAMHistone-lysine N-methyltransferase KMT5B2.1.1.430.440
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.440
3t7vSAM3-methylornithine synthase/0.440
3u78E67Lysine-specific demethylase 7A1.14.110.440
3vyfVYFRenin3.4.23.150.440
3w8fNAD3-hydroxybutyrate dehydrogenase/0.440
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.440
4a802ANMajor pollen allergen Bet v 1-A/0.440
4aa5NQBMitogen-activated protein kinase 14/0.440
4b741LHGenome polyprotein3.4.21.980.440
4c6uTLG3-oxoacyl-ACP synthase/0.440
4ehyADPTetraacyldisaccharide 4'-kinase/0.440
4ejgNCTCytochrome P450 2A131.14.14.10.440
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.440
4fncHMUG/T mismatch-specific thymine DNA glycosylase3.2.2.290.440
4jtrIBPAldo-keto reductase family 1 member C2/0.440
4lxm1YUBeta-secretase 13.4.23.460.440
4o4eATPKinase/0.440
4tlnLNOThermolysin3.4.24.270.440
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.440
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.440