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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.26

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.261.000
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.621
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.609
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.601
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.590
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.585
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.568
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.562
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.561
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.554
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.548
2jedLG8Protein kinase C theta type2.7.11.130.547
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.542
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.540
3du8553Glycogen synthase kinase-3 beta2.7.11.260.538
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.538
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.536
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.535
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.535
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.533
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.532
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.531
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.530
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.529
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.529
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.527
2i0ePDSProtein kinase C beta type2.7.11.130.525
4bchT7ZCyclin-dependent kinase 92.7.11.220.523
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.516
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.512
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.512
3e5aVX6Aurora kinase A2.7.11.10.511
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.508
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.508
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.508
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.506
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.504
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.504
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.503
4ix6ADPUncharacterized protein/0.503
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
3l0lHC3Nuclear receptor ROR-gamma/0.501
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.500
3iw4LW4Protein kinase C alpha type2.7.11.130.500
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.500
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.499
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
3vo30KFVascular endothelial growth factor receptor 22.7.10.10.498
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.498
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.497
4dbzNDPPutative ketoacyl reductase1.3.10.497
4l8u9AZSerum albumin/0.497
1qoqIGPTryptophan synthase alpha chain/0.495
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.494
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.493
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.492
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.491
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.491
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.490
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.490
4g48PZBMycocyclosin synthase1.14.21.90.490
4othDRNSerine/threonine-protein kinase N1/0.490
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.489
3blrCPBCyclin-dependent kinase 92.7.11.220.489
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.488
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.488
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.488
1kkq471Peroxisome proliferator-activated receptor alpha/0.486
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.486
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.486
1zeoC01Peroxisome proliferator-activated receptor gamma/0.486
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.486
2ev9NAPShikimate dehydrogenase (NADP(+))/0.486
3gc9B45Mitogen-activated protein kinase 112.7.11.240.486
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.485
2itqITQEpidermal growth factor receptor2.7.10.10.485
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.485
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.485
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.485
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.485
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.484
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.483
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.483
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.483
3vf9477Tyrosine-protein kinase SYK2.7.10.20.483
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.483
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.483
4nb6444Nuclear receptor ROR-gamma/0.483
4nm7ADPGlycogen synthase kinase-3 beta2.7.11.260.483
1oiyN41Cyclin-dependent kinase 22.7.11.220.482
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.482
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.482
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.482
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.482
4g2fC07Ephrin type-A receptor 32.7.10.10.482
4ykfFADAlkyl hydroperoxide reductase subunit F1.8.10.482
1ci7UMPThymidylate synthase2.1.1.450.481
3oom507Activin receptor type-12.7.11.300.481
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.481
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.481
2hk9NAPShikimate dehydrogenase (NADP(+))/0.480
2ptfFMNUncharacterized protein MTH_863/0.480
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.480
3zh8C58Protein kinase C iota type2.7.11.130.480
1ppjANYCytochrome b/0.479
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.479
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.478
1x8lOXRRetinol dehydratase/0.478
2zjwREFCasein kinase II subunit alpha2.7.11.10.478
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.478
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.478
1jpaANPEphrin type-B receptor 22.7.10.10.477
2vwx7X4Ephrin type-B receptor 42.7.10.10.477
3bfb9ODPheromone-binding protein ASP1/0.477
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.477
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.477
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.476
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.476
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.476
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.476
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.476
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.476
4gk4L90Ephrin type-A receptor 32.7.10.10.476
4gmy0X5Tyrosine-protein kinase JAK2/0.476
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.475
1w1rZEACytokinin dehydrogenase 11.5.99.120.475
3nglNAPBifunctional protein FolD/0.475
3nj0PYVAbscisic acid receptor PYL2/0.475
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.475
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.475
1k7fIAVTryptophan synthase alpha chain/0.474
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.474
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.474
2qo9ANPEphrin type-A receptor 32.7.10.10.474
2vcmM11Isopenicillin N synthase1.21.3.10.474
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.474
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.474
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.474
4lopSB4Mitogen-activated protein kinase 14/0.474
2uxpCLMHTH-type transcriptional regulator TtgR/0.473
2uxuNARHTH-type transcriptional regulator TtgR/0.473
2zevB71Geranylgeranyl pyrophosphate synthase/0.473
3kr6UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.473
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.473
4bgg844Activin receptor type-12.7.11.300.473
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.473
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.472
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.472
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.472
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.472
3eb0DRKUncharacterized protein/0.472
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.472
4dc0NDPPutative ketoacyl reductase1.3.10.472
4ktl1CQCytochrome P450/0.472
4l9q9TPSerum albumin/0.472
4qa0SHHHistone deacetylase 83.5.1.980.472
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.471
1rfuADPPyridoxal kinase2.7.1.350.471
2hog710Serine/threonine-protein kinase Chk12.7.11.10.471
2zb45OPProstaglandin reductase 21.3.1.480.471
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3zkuHCVIsopenicillin N synthase1.21.3.10.471
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.471
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.471
4oavACP2-5A-dependent ribonuclease3.1.260.471
4pd6URINucleoside permease/0.471
1e7aPFLSerum albumin/0.470
1s19MC9Vitamin D3 receptor/0.470
1swtBTNStreptavidin/0.470
2vrbNAPTriphenylmethane reductase/0.470
2z4y252Geranylgeranyl pyrophosphate synthase/0.470
3adaNADSubunit alpha of sarocosine oxidase/0.470
3kytHC2Nuclear receptor ROR-gamma/0.470
3t2zFADSulfide-quinone reductase/0.470
4dymIYZActivin receptor type-12.7.11.300.470
4egnTWOCytochrome P450/0.470
4gk2L66Ephrin type-A receptor 32.7.10.10.470
4eilCB3Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.469
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.469
4iarERM5-hydroxytryptamine receptor 1B/0.469
3reyXACAdenosine receptor A2a/0.469
2acxANPG protein-coupled receptor kinase 62.7.11.160.468
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.468
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.468
2po7CHDFerrochelatase, mitochondrial4.99.1.10.468
2x7hPFNProstaglandin reductase 310.468
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.468
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3nhwZXZRibosyldihydronicotinamide dehydrogenase [quinone]/0.468
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.468
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.468
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.468
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.468
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.468
5drdATPAurora kinase A2.7.11.10.468
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
1hvyD16Thymidylate synthase2.1.1.450.467
1lp4ANPCasein kinase II subunit alpha2.7.11.10.467
1xddAAYIntegrin alpha-L/0.467
2nr4FMNConserved protein/0.467
3a60STURibosomal protein S6 kinase beta-12.7.11.10.467
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.467
3l6jZ90Alr2278 protein/0.467
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.467
3t2kFADSulfide-quinone reductase/0.467
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.467
4oauADP2-5A-dependent ribonuclease3.1.260.467
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.467
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.466
2dwbANPAurora kinase A2.7.11.10.466
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.466
2hb7O1CVitamin D3 receptor/0.466
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.466
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.466
3qc9ADPRhodopsin kinase/0.466
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.466
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.466
4ktkKTKCytochrome P450/0.466
4l9zCOAL-malyl-CoA/beta-methylmalyl-CoA lyase4.1.3.240.466
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.465
1nytNAPShikimate dehydrogenase (NADP(+))/0.465
1q1rFADPutidaredoxin reductase1.18.1.50.465
2ojg19AMitogen-activated protein kinase 12.7.11.240.465
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.465
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.465
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.465
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.465
4i22IREEpidermal growth factor receptor2.7.10.10.465
4jq8KJ8Epidermal growth factor receptor2.7.10.10.465
4jvlESTEstrogen sulfotransferase2.8.2.40.465
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.465
4pleCPSNuclear receptor subfamily 5 group A member 2/0.465
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
5k2dZMAAdenosine receptor A2a/0.465
1bygSTUTyrosine-protein kinase CSK/0.464
1sozVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.464
1y0s331Peroxisome proliferator-activated receptor delta/0.464
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.464
2q9fC3SCholesterol 24-hydroxylase/0.464
2wd9IBPAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.464
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.464
2zlcVDXVitamin D3 receptor/0.464
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.464
3ctj320Hepatocyte growth factor receptor2.7.10.10.464
3cyz9ODPheromone-binding protein ASP1/0.464
3h0a9RARetinoic acid receptor RXR-alpha/0.464
3hllI45Mitogen-activated protein kinase 14/0.464
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.464
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
4j97ACPFibroblast growth factor receptor 2/0.464
4l4xNDPAmphI/0.464
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.464
5uviZMAAdenosine receptor A2a/0.464
1k0lFADp-hydroxybenzoate hydroxylase/0.463
1r6g442Thyroid hormone receptor beta/0.463
2a94AP0L-lactate dehydrogenase1.1.1.270.463
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.463
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.463
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.463
2uxiG50HTH-type transcriptional regulator TtgR/0.463
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.463
2y6o1N1Ephrin type-A receptor 42.7.10.10.463
3c3dFO12-phospho-L-lactate transferase/0.463
3dds26BGlycogen phosphorylase, liver form2.4.1.10.463
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.463
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.463
3p8jFMNPentaerythritol tetranitrate reductase/0.463
3pe2E1BCasein kinase II subunit alpha2.7.11.10.463
4ez8DHFThymidylate synthase2.1.1.450.463
4g47TZFMycocyclosin synthase1.14.21.90.463
4hvh19RTyrosine-protein kinase JAK32.7.10.20.463
4ktf1TMCytochrome P450/0.463
4kugNAD3-hydroxybutyryl-CoA dehydrogenase/0.463
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.463
4oztP1AEcdysone receptor, putative/0.463
1dkfBMSRetinoic acid receptor alpha/0.462
1g28FMNPHY3/0.462
1kl2FONSerine hydroxymethyltransferase/0.462
1nvtNAPShikimate dehydrogenase (NADP(+))/0.462
1pkdUCNCyclin-dependent kinase 22.7.11.220.462
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.462
2x6dX6DAurora kinase A2.7.11.10.462
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.462
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.462
3dd125DGlycogen phosphorylase, liver form2.4.1.10.462
3pl8FADPyranose 2-oxidase/0.462
3rpr25ZCyclin-dependent kinase 22.7.11.220.462
4a6nFADTetX family tetracycline inactivation enzyme/0.462
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.462
4g1y0VOVitamin D3 receptor A/0.462
4ix5ANPUncharacterized protein/0.462
1g4sTPSThiamine-phosphate synthase/0.461
2hw2RFPRifampin ADP-ribosyl transferase/0.461
3dt1P40Mitogen-activated protein kinase 14/0.461
3ijdC2FMethylenetetrahydrofolate reductase/0.461
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.461
3rmf20ZCyclin-dependent kinase 22.7.11.220.461
3vt5YI2Vitamin D3 receptor/0.461
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
4g2gTDHMycocyclosin synthase1.14.21.90.461
4kwi1TJReductase homolog/0.461
4lsjLSJGlucocorticoid receptor/0.461
4qmySTUSerine/threonine-protein kinase 242.7.11.10.461
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.460
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.460
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2uxoTACHTH-type transcriptional regulator TtgR/0.460
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.460
3s1dZIRCytokinin dehydrogenase 11.5.99.120.460
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.460
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.460
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.460
4jq4IMNAldo-keto reductase family 1 member C2/0.460
1h1r6CPCyclin-dependent kinase 22.7.11.220.459
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.459
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.459
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.459
1wsvTHHAminomethyltransferase, mitochondrial/0.459
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.459
2gjlFMNNitronate monooxygenase1.13.12.160.459
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.459
2jlbUDMUncharacterized protein/0.459
2uxhQUEHTH-type transcriptional regulator TtgR/0.459
2ym1FADPhenylacetone monooxygenase1.14.13.920.459
3a1l2CCCytochrome P450/0.459
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
3da24MDCarbonic anhydrase 134.2.1.10.459
3hx4ANPCalmodulin-domain protein kinase 1/0.459
3owj1ELCasein kinase II subunit alpha2.7.11.10.459
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.459
3sz0FADSulfide-quinone reductase/0.459
4olfHFGProline--tRNA ligase6.1.1.150.459
4qa2SHHHistone deacetylase 83.5.1.980.459
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
5dp2NAPCurF/0.459
1cqp803Integrin alpha-L/0.458
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.458
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.458
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.458
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.458
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.458
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.458
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.458
4ead0NPThymidine phosphorylase2.4.2.40.458
4iq71G9Mycocyclosin synthase1.14.21.90.458
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.458
4z34ON7Lysophosphatidic acid receptor 1/0.458
1bwlFMNNADPH dehydrogenase 11.6.99.10.457
1klkPMDDihydrofolate reductase1.5.1.30.457
2m56CAMCamphor 5-monooxygenase1.14.15.10.457
2xpwOTCTetracycline repressor protein class D/0.457
2yxuATPPyridoxal kinase2.7.1.350.457
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.457
3pe6ZYHMonoglyceride lipase/0.457
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.457
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.457
4bfxZVXPantothenate kinase2.7.1.330.457
4c02TAKActivin receptor type-12.7.11.300.457
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.457
4g1z0VPVitamin D3 receptor A/0.457
4i2q1BTGag-Pol polyprotein2.7.7.490.457
4riyADPEpidermal growth factor receptor2.7.10.10.457
5eccNAPDehydrofolate reductase type I/0.457
1ao8MTXDihydrofolate reductase1.5.1.30.456
1r00SAHAclacinomycin 10-hydroxylase RdmB4.1.10.456
1txiTX5Vitamin D3 receptor/0.456
1xuoLA1Integrin alpha-L/0.456
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.456
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.456
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.456
3be9P04Casein kinase II subunit alpha2.7.11.10.456
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.456
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.456
3h3t16HCollagen type IV alpha-3-binding protein/0.456
3ibqATPPyridoxal kinase/0.456
3slkNDPPolyketide synthase extender module 2/0.456
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.456
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.456
4qedNAPElxO/0.456
4tuvCPZCytochrome P450 1191.140.456
4uxq0LIFibroblast growth factor receptor 42.7.10.10.456
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.455
1ke9LS5Cyclin-dependent kinase 22.7.11.220.455
1m9tH4BNitric oxide synthase, inducible1.14.13.390.455
1osvCHCBile acid receptor/0.455
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.455
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.455
2g2zCOZMalonyl CoA-acyl carrier protein transacylase2.3.1.390.455
2hamC33Vitamin D3 receptor/0.455
2iw84SPCyclin-dependent kinase 22.7.11.220.455
2j4z626Aurora kinase A2.7.11.10.455
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.455
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3d75NBBPheromone-binding protein ASP1/0.455
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3h3r14HCollagen type IV alpha-3-binding protein/0.455
3new3NEMitogen-activated protein kinase 14/0.455
3vtdTKDVitamin D3 receptor/0.455
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.455
4eevL1XHepatocyte growth factor receptor2.7.10.10.455
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.455
1dduCB3Thymidylate synthase/0.454
1dz4CAMCamphor 5-monooxygenase1.14.15.10.454
1lriCLRBeta-elicitin cryptogein/0.454
1obnASVIsopenicillin N synthase1.21.3.10.454
1unlRRCCyclin-dependent-like kinase 52.7.11.10.454
1x2hLPALipoate-protein ligase A6.3.1.200.454
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.454
2cchATPCyclin-dependent kinase 22.7.11.220.454
2ed3SAHDiphthine synthase/0.454
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.454
2iorADPChaperone protein HtpG/0.454
2itpAEEEpidermal growth factor receptor2.7.10.10.454
2qocANPEphrin type-A receptor 32.7.10.10.454
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.454
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.454
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.454
3fln3FNMitogen-activated protein kinase 14/0.454
3hk1B64Fatty acid-binding protein, adipocyte/0.454
3iaeD7KBenzaldehyde lyase/0.454
3kpkFADSulfide-quinone reductase/0.454
3lqfNADGalactitol dehydrogenase/0.454
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.454
3p62FMNPentaerythritol tetranitrate reductase/0.454
3roy22ZCyclin-dependent kinase 22.7.11.220.454
3s79ASDAromatase1.14.14.140.454
4bfpSWYTankyrase-22.4.2.300.454
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.454
4f630S7Fibroblast growth factor receptor 1/0.454
4fw05KJNitric oxide synthase, brain1.14.13.390.454
4i8vBHFCytochrome P450 1A11.14.14.10.454
4imoPWZProstaglandin-H2 D-isomerase5.3.99.20.454
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.454
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.454
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.454
6cp4CAMCamphor 5-monooxygenase1.14.15.10.454
5k2bZMAAdenosine receptor A2a/0.454
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.453
1eioGCHGastrotropin/0.453
1fgiSU1Fibroblast growth factor receptor 1/0.453
1fmjRTLRetinol dehydratase/0.453
1g63FMNEpidermin decarboxylase4.1.10.453
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.453
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.453
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.453
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.453
3c1xCKKHepatocyte growth factor receptor2.7.10.10.453
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.453
3h65I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.453
3sm2478Putative gag-pro-pol polyprotein/0.453
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.453
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.453
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.453
4g210VPVitamin D3 receptor A/0.453
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.453
4jq7KJQEpidermal growth factor receptor2.7.10.10.453
4jqeANPCasein kinase II subunit alpha2.7.11.10.453
4lfiGNPCasein kinase II subunit alpha2.7.11.10.453
4p6wMOFGlucocorticoid receptor/0.453
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.453
5auuLU2Death-associated protein kinase 12.7.11.10.453
1fmlRTLRetinol dehydratase/0.452
1m9m6NINitric oxide synthase, endothelial1.14.13.390.452
1os1ATPPhosphoenolpyruvate carboxykinase (ATP)/0.452
1tysDHFThymidylate synthase/0.452
2bbqPFGThymidylate synthase/0.452
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.452
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.452
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.452
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.452
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
3dogNNNCyclin-dependent kinase 22.7.11.220.452
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3g7jGTXGlutathione transferase GST1-4/0.452
3gbuATPUncharacterized sugar kinase PH14592.7.10.452
3gwfFADCyclohexanone monooxygenase/0.452
3h18PMSEsterase/lipase/0.452
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
3mtfA3FActivin receptor type-12.7.11.300.452
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.452
4bfzZVZPantothenate kinase2.7.1.330.452
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.452
4f640S8Fibroblast growth factor receptor 1/0.452
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.452
4iah1DXAlr2278 protein/0.452
4jqh1MFAlr2278 protein/0.452
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.452
4nmdFDABifunctional protein PutA/0.452
5k2cZMAAdenosine receptor A2a/0.452
1h1s4SPCyclin-dependent kinase 22.7.11.220.451
1oiuN76Cyclin-dependent kinase 22.7.11.220.451
1rdtL79Retinoic acid receptor RXR-alpha/0.451
2ay95PVAromatic-amino-acid aminotransferase2.6.1.570.451
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.451
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.451
3koo24DBifunctional epoxide hydrolase 23.3.2.100.451
3p74FMNPentaerythritol tetranitrate reductase/0.451
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.451
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
4cukNAID-lactate dehydrogenase/0.451
4nka2K7Fibroblast growth factor receptor 1/0.451
5iubCLRAdenosine receptor A2a/0.451
1cbqRE9Cellular retinoic acid-binding protein 2/0.450
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.450
1rbzKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.450
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.450
2hb8MVDVitamin D3 receptor/0.450
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.450
2i40BLZCyclin-dependent kinase 22.7.11.220.450
2imkGTXAGAP009194-PA/0.450
2tscCB3Thymidylate synthase/0.450
2vd5BI8Myotonin-protein kinase2.7.11.10.450
2x9dITCTetracycline repressor protein class D/0.450
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.450
3bfa9ODOdorant binding protein ASP1/0.450
3bqdDAYGlucocorticoid receptor/0.450
3fp0FP015-O-acetyltransferase/0.450
3jynNDPQuinone oxidoreductase/0.450
3mcyZH1FimH/0.450
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3v3vMYUMitogen-activated protein kinase 82.7.11.240.450
3w0jT08Vitamin D3 receptor/0.450
4eilUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
4enhFVXCholesterol 24-hydroxylase/0.450
4fyn0VETyrosine-protein kinase SYK2.7.10.20.450
4jxrACOAcetyltransferase/0.450
4l17DNQGlutamate receptor 2/0.450
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.450
4q71FADBifunctional protein PutA/0.450
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.450
4wqmFADToluene-4-monooxygenase electron transfer component1.18.1.30.450
5cvhADPCasein kinase II subunit alpha2.7.11.10.450
1k7l544Peroxisome proliferator-activated receptor alpha/0.449
1ke6LS2Cyclin-dependent kinase 22.7.11.220.449
1kzjCB3Thymidylate synthase/0.449
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.449
1s6qTPBGag-Pol polyprotein2.7.7.490.449
2xw7NDPDihydrofolate reductase/0.449
3ddw055Glycogen phosphorylase, liver form2.4.1.10.449
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
3elm24FCollagenase 33.4.240.449
3hub469Mitogen-activated protein kinase 14/0.449
3iqeH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.449
3kljFADNADH-rubredoxin oxidoreductase1.18.1.10.449
3mdvCL6Cholesterol 24-hydroxylase/0.449
3qtsX46Cyclin-dependent kinase 22.7.11.220.449
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.449
3s4qNK0Mitogen-activated protein kinase 14/0.449
3sruQ26Dihydrofolate reductase1.5.1.30.449
3tucFPWTyrosine-protein kinase SYK2.7.10.20.449
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4aotGW8Serine/threonine-protein kinase 102.7.11.10.449
4b4vL34Bifunctional protein FolD/0.449
4bfyZVYPantothenate kinase2.7.1.330.449
4dgmAGICasein kinase II subunit alpha2.7.11.10.449
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.449
4ia1BIVVitamin D3 receptor A/0.449
4loqSB4Mitogen-activated protein kinase 14/0.449
4o0sADNAurora kinase A2.7.11.10.449
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.449
4wboANWRhodopsin kinase/0.449
4xivACPChemotaxis protein CheA2.7.13.30.449
5dt4ATPAurora kinase A2.7.11.10.449
5k2aZMAAdenosine receptor A2a/0.449
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1fvt106Cyclin-dependent kinase 22.7.11.220.448
1hpzAAPGag-Pol polyprotein2.7.7.490.448
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1mq4ADPAurora kinase A2.7.11.10.448
1nhz486Glucocorticoid receptor/0.448
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
1x7gNAPPutative ketoacyl reductase1.3.10.448
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.448
2c31ADPOxalyl-CoA decarboxylase4.1.1.80.448
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.448
2of4979Tyrosine-protein kinase Lck2.7.10.20.448
2vx17X8Ephrin type-B receptor 42.7.10.10.448
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.448
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.448
3f82353Hepatocyte growth factor receptor2.7.10.10.448
3fr5I4AFatty acid-binding protein, adipocyte/0.448
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.448
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.448
3nga3NGCasein kinase II subunit alpha2.7.11.10.448
3oxfSAHHistone-lysine N-methyltransferase SMYD32.1.1.430.448
3uleC69Actin-related protein 3/0.448
4fv7E94Mitogen-activated protein kinase 12.7.11.240.448
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.448
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.448
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.448
4mihFADPyranose 2-oxidase1.1.3.100.448
4qmzB49Serine/threonine-protein kinase 242.7.11.10.448
4qnaX11Serine/threonine-protein kinase 242.7.11.10.448
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.448
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.448
4y93746Tyrosine-protein kinase/0.448
5e8xSTUTGF-beta receptor type-12.7.11.300.448
1lb9DNQGlutamate receptor 2/0.447
1m8h6NINitric oxide synthase, inducible1.14.13.390.447
1p93DEXGlucocorticoid receptor/0.447
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.447
1xefATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.447
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
2abbFMNPentaerythritol tetranitrate reductase/0.447
2o0uC0MMitogen-activated protein kinase 102.7.11.240.447
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.447
2xk730ESerine/threonine-protein kinase Nek22.7.11.10.447
2yn8STUEphrin type-B receptor 42.7.10.10.447
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.447
3c50ADPRhodopsin kinase/0.447
3efwAK8Aurora kinase A2.7.11.10.447
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.447
3juqAJDPhenazine biosynthesis protein A/B/0.447
3kpzZNEVitamin D3 receptor/0.447
3mjeNDPAmphB/0.447
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.447
3p67FMNPentaerythritol tetranitrate reductase/0.447
3r9dX6BCyclin-dependent kinase 22.7.11.220.447
3t113T1Gag-Pol polyprotein3.4.23.160.447
3t8oATPRhodopsin kinase/0.447
3u9y09LTankyrase-22.4.2.300.447
4b4w9L9Bifunctional protein FolD/0.447
4dc1NDPPutative ketoacyl reductase1.3.10.447
4dru0LNGenome polyprotein2.7.7.480.447
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.447
4fhh0U3Vitamin D3 receptor A/0.447
4g95OAGDihydrofolate reductase1.5.1.30.447
4h4vFADBiphenyl dioxygenase ferredoxin reductase subunit/0.447
4ia3BIVVitamin D3 receptor A/0.447
4jr3KJREpidermal growth factor receptor2.7.10.10.447
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.447
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.447
4q72FADBifunctional protein PutA/0.447
4qmpDKISerine/threonine-protein kinase 242.7.11.10.447
4xumIMNPeroxisome proliferator-activated receptor gamma/0.447
5iua6DXAdenosine receptor A2a/0.447
1db1VDXVitamin D3 receptor/0.446
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1jujLYAThymidylate synthase2.1.1.450.446
1m9k7NINitric oxide synthase, endothelial1.14.13.390.446
1rkhVD2Vitamin D3 receptor/0.446
1szcCNANAD-dependent protein deacetylase HST23.5.10.446
1tduCB3Thymidylate synthase/0.446
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.446
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.446
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.446
2ittAEEEpidermal growth factor receptor2.7.10.10.446
2xvdAS6Ephrin type-B receptor 42.7.10.10.446
2zdt46CMitogen-activated protein kinase 102.7.11.240.446
3b7dCNIGlutamate receptor 2/0.446
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.446
3unj0BXCyclin-dependent kinase 22.7.11.220.446
3vt9YI4Vitamin D3 receptor/0.446
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.446
4e730NRMitogen-activated protein kinase 82.7.11.240.446
4fdpFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.446
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.446
4g3jVNTLanosterol 14-alpha-demethylase/0.446
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.446
4klaCHDFerrochelatase, mitochondrial4.99.1.10.446
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.446
4u8iFDAUDP-galactopyranose mutase/0.446
4uqsINENitric oxide synthase oxygenase1.14.13.1650.446
4wsqKSAAP2-associated protein kinase 12.7.11.10.446
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.446
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.446
5dn3ATPAurora kinase A2.7.11.10.446
5iu4ZMAAdenosine receptor A2a/0.446
3emlZMAAdenosine receptor A2a/0.446
1ie8KH1Vitamin D3 receptor/0.445
1oi9N20Cyclin-dependent kinase 22.7.11.220.445
1qvnFRIInterleukin-2/0.445
1tysTMPThymidylate synthase/0.445
1vyrFMNPentaerythritol tetranitrate reductase/0.445
2bgiFADNADPH:ferredoxin reductase/0.445
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.445
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.445
2j5xGSPADP-ribosylation factor 6/0.445
2pvmP29Casein kinase II subunit alpha2.7.11.10.445
2w3wVG9Dihydrofolate reductase/0.445
2wgjVGHHepatocyte growth factor receptor2.7.10.10.445
2zbaZBATrichothecene 3-O-acetyltransferase/0.445
3ac1KZITyrosine-protein kinase Lck2.7.10.20.445
3bgxMEFThymidylate synthase/0.445
3cz09ODPheromone-binding protein ASP1/0.445
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.445
3qlrNDPDihydrofolate reductase1.5.1.30.445
3tqxPLP2-amino-3-ketobutyrate coenzyme A ligase/0.445
4asg814ATP-dependent molecular chaperone HSP82/0.445
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4cdmFO1Deoxyribodipyrimidine photolyase/0.445
4e5yNDPGDP-L-fucose synthase1.1.1.2710.445
4fkv61KCyclin-dependent kinase 22.7.11.220.445
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.445
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.445
4fx360KCyclin-dependent kinase 22.7.11.220.445
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.445
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.445
4jboWPHAurora kinase A2.7.11.10.445
4jvmXDIEstrogen sulfotransferase2.8.2.40.445
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.445
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
4ocvANPAminoglycoside phosphotransferase/0.445
4v2gITCTetracycline repressor protein class D/0.445
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.445
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.445
5fm7ADPRuvB-like helicase/0.445
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.444
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.444
1pjcNADAlanine dehydrogenase/0.444
1pkfEPDEpothilone C/D epoxidase1.140.444
2a8xFADDihydrolipoyl dehydrogenase1.8.1.40.444
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
2chlDKICasein kinase I isoform gamma-32.7.11.10.444
2cjpVPREpoxide hydrolase/0.444
2ewaSB2Mitogen-activated protein kinase 14/0.444
2fonFADAcyl-coenzyme A oxidase/0.444
2j2pSC2Ficolin-2/0.444
2om9AJAPeroxisome proliferator-activated receptor gamma/0.444
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.444
2q46NAPUncharacterized protein At5g02240/0.444
2x1nX1NCyclin-dependent kinase 22.7.11.220.444
2xikJ60Serine/threonine-protein kinase 252.7.11.10.444
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.444
2zz0FADThioredoxin reductase 1, cytoplasmic1.8.1.90.444
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3c3xNAPEugenol synthase 11.1.1.3180.444
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.444
3fwjCAMCamphor 5-monooxygenase1.14.15.10.444
3h06VBPGlutamate receptor 2/0.444
3i6qNDPPutative leucoanthocyanidin reductase 1/0.444
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.444
3ivcFG4Pantothenate synthetase6.3.2.10.444
3mtlFEFCyclin-dependent kinase 162.7.11.220.444
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.444
3njoPYVAbscisic acid receptor PYR1/0.444
3own3OWRenin3.4.23.150.444
3r3b4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.444
3slz3TLPutative gag-pro-pol polyprotein/0.444
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.444
3wmxNADNAD dependent epimerase/dehydratase/0.444
4a9e3PFBromodomain-containing protein 2/0.444
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.444
4erkOLOMitogen-activated protein kinase 12.7.11.240.444
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.444
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.444
4g1d0VKVitamin D3 receptor A/0.444
4ips1G4Mycocyclosin synthase1.14.21.90.444
4isg1FYGlucokinase2.7.1.20.444
4ix4ADPUncharacterized protein/0.444
4lwbQJ8Nitric oxide synthase oxygenase1.14.13.1650.444
4o71CPBBromodomain-containing protein 4/0.444
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.444
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.444
3qakUKAAdenosine receptor A2a/0.444
1di8DTQCyclin-dependent kinase 22.7.11.220.443
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.443
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.443
1ojtFADDihydrolipoyl dehydrogenase/0.443
1phePIYCamphor 5-monooxygenase1.14.15.10.443
1q5dEPBEpothilone C/D epoxidase1.140.443
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1t2cNAIL-lactate dehydrogenase1.1.1.270.443
1ysx4EBSerum albumin/0.443
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2cig1DGDihydrofolate reductase1.5.1.30.443
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.443
2eleSAHDiphthine synthase/0.443
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.443
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.443
2rhtC1E2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.443
2vnhFADNADPH:ferredoxin reductase/0.443
2vwz7X6Ephrin type-B receptor 42.7.10.10.443
3cr3ADPPTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.443
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.443
3fktSIIBeta-secretase 13.4.23.460.443
3h3sH15Collagen type IV alpha-3-binding protein/0.443
3imeBZ2Pantothenate synthetase6.3.2.10.443
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3iw7IPKMitogen-activated protein kinase 14/0.443
3mdmFJZCholesterol 24-hydroxylase/0.443
3tnwF18Cyclin-dependent kinase 22.7.11.220.443
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.443
4at0FADPossible succinate dehydrogenase/0.443
4bfsZVSPantothenate kinase2.7.1.330.443
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.443
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4f1yCNIGlutamate receptor 3/0.443
4gg70J8Hepatocyte growth factor receptor2.7.10.10.443
4ib4ERM5-hydroxytryptamine receptor 2B/0.443
4iteTEYVitamin D3 receptor/0.443
4jlk1NODeoxycytidine kinase2.7.1.740.443
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.443
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.443
4ug91EWNitric oxide synthase oxygenase1.14.13.1650.443
4xivADPChemotaxis protein CheA2.7.13.30.443
5fs6FADApoptosis-inducing factor 1, mitochondrial1.1.10.443
5fwnNAPPutative dehydrogenase/0.443
3sn6P0GBeta-2 adrenergic receptor/0.443
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.442
1ep4S11Gag-Pol polyprotein2.7.7.490.442
1f4fTP3Thymidylate synthase/0.442
1g3mPCQEstrogen sulfotransferase2.8.2.40.442
1jstATPCyclin-dependent kinase 22.7.11.220.442
1jxzBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.442
1ke7LS3Cyclin-dependent kinase 22.7.11.220.442
1ml6GBXGlutathione S-transferase A22.5.1.180.442
1phgMYTCamphor 5-monooxygenase1.14.15.10.442
1rx8NAPDihydrofolate reductase1.5.1.30.442
1ykdCMPAdenylate cyclase/0.442
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2bxmIMNSerum albumin/0.442
2ejvNADL-threonine 3-dehydrogenase/0.442
2ghlLIBMitogen-activated protein kinase 14/0.442
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.442
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.442
2y60M8FIsopenicillin N synthase1.21.3.10.442
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
3cntFADPolyamine oxidase FMS1/0.442
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.442
3l8sBFFMitogen-activated protein kinase 14/0.442
3mb601ICasein kinase II subunit alpha2.7.11.10.442
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.442
3r9hZ67Cyclin-dependent kinase 22.7.11.220.442
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.442
3vrwYS5Vitamin D3 receptor/0.442
3vt8YI3Vitamin D3 receptor/0.442
3w32W32Epidermal growth factor receptor2.7.10.10.442
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.442
4bcpT3CCyclin-dependent kinase 22.7.11.220.442
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.442
4ejh0QACytochrome P450 2A131.14.14.10.442
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.442
4lxhC1EAlpha/beta hydrolase fold/0.442
4mppTZDBenzoylformate decarboxylase4.1.1.70.442
4nc3ERM5-hydroxytryptamine receptor 2B/0.442
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.442
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
5jlaNADPutative short-chain dehydrogenase/reductase/0.442
1db48INPhospholipase A2, membrane associated/0.441
1diuBDMDihydrofolate reductase1.5.1.30.441
1drhNAPDihydrofolate reductase1.5.1.30.441
1fm4DXCMajor pollen allergen Bet v 1-L/0.441
1fm69CRRetinoic acid receptor RXR-alpha/0.441
1i2lDCSAminodeoxychorismate lyase4.1.3.380.441
1kt3RTLRetinol-binding protein 4/0.441
1m52P17Tyrosine-protein kinase ABL12.7.10.20.441
2aclREARetinoic acid receptor RXR-alpha/0.441
2jkkBI9Focal adhesion kinase 12.7.10.20.441
2kceD16Thymidylate synthase/0.441
2ociTYCValacyclovir hydrolase3.10.441
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.441
2pvnP63Casein kinase II subunit alpha2.7.11.10.441
2rqfJH3Hemolymph juvenile hormone binding protein/0.441
2vbpVB1Isopenicillin N synthase1.21.3.10.441
2vwy7X5Ephrin type-B receptor 42.7.10.10.441
2xlsFADPutative flavin-containing monooxygenase/0.441
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.441
3a783EVVitamin D3 receptor/0.441
3ac2KSETyrosine-protein kinase Lck2.7.10.20.441
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.441
3dufR1TPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.441
3dufR1TPyruvate dehydrogenase E1 component subunit beta1.2.4.10.441
3eljGS7Mitogen-activated protein kinase 82.7.11.240.441
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.441
3phjDHKShikimate dehydrogenase (NADP(+))/0.441
3r0tFU9Casein kinase II subunit alpha2.7.11.10.441
3v94WYQPhosphodiesterase/0.441
4ap1NAPSteroid monooxygenase/0.441
4dcaADPAminoglycoside phosphotransferase/0.441
4dpuAGSMevalonate diphosphate decarboxylase/0.441
4ewqMWLMitogen-activated protein kinase 14/0.441
4fgj1PQRibosyldihydronicotinamide dehydrogenase [quinone]/0.441
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.441
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.441
4h6pFMNChromate reductase/0.441
4jufTPPBenzoylformate decarboxylase4.1.1.70.441
4klrCHDFerrochelatase, mitochondrial4.99.1.10.441
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.441
4nks2M2Fibroblast growth factor receptor 1/0.441
4q73FADBifunctional protein PutA/0.441
4qjqOTRLactoperoxidase/0.441
4utdACPAurora kinase A2.7.11.10.441
5cb3APRO-acetyl-ADP-ribose deacetylase/0.441
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.440
1dz8CAMCamphor 5-monooxygenase1.14.15.10.440
1e9hINRCyclin-dependent kinase 22.7.11.220.440
1g4tFTPThiamine-phosphate synthase/0.440
1oecAA2Fibroblast growth factor receptor 2/0.440
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1rbqKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.440
1t87CAMCamphor 5-monooxygenase1.14.15.10.440
1trgCB3Thymidylate synthase/0.440
1vi2NADQuinate/shikimate dehydrogenase/0.440
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2bheBRYCyclin-dependent kinase 22.7.11.220.440
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.440
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.440
2j0m4STFocal adhesion kinase 12.7.10.20.440
2jn3JN3Fatty acid-binding protein, liver/0.440
2lbaCHOFatty acid binding protein 6/0.440
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.440
2wo7ASVIsopenicillin N synthase1.21.3.10.440
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.440
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3asjXYMHomoisocitrate dehydrogenase/0.440
3d1z017Gag-Pol polyprotein3.4.23.160.440
3e7iH4BNitric oxide synthase, inducible1.14.13.390.440
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.440
3grySAMProbable ribosomal RNA small subunit methyltransferase A/0.440
3ih0ANPUncharacterized sugar kinase PH14592.7.10.440
3nfrEWQRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
3qnlROABasic phospholipase A2 homolog piratoxin-1/0.440
3stv3HOMethylketone synthase I/0.440
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.440
4a2jAS0Progesterone receptor/0.440
4b3aTACTetracycline repressor protein class D/0.440
4cnjFADL-amino acid oxidase/0.440
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.440
4h9506UDihydrofolate reductase1.5.1.30.440
4hnc0UTMandelate racemase/0.440
4ia7BIVVitamin D3 receptor A/0.440
4qe6JN3Bile acid receptor/0.440
4rupH97Vitamin D3 receptor A/0.440
4x5jFOLDihydrofolate reductase1.5.1.30.440
4zvmDM2Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
5iu86DZAdenosine receptor A2a/0.440