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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3inqX0JBcl-2-like protein 1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3inqX0JBcl-2-like protein 1/1.000
3wizLC6Bcl-2-like protein 1/0.629
2yxjN3CBcl-2-like protein 1/0.593
3qkdHI0Bcl-2-like protein 1/0.575
2o2mLI0Bcl-2-like protein 1/0.556
1rt7UC4Gag-Pol polyprotein2.7.7.490.545
3d74NBBPheromone-binding protein ASP1/0.511
4qnq1XJBcl-2-like protein 1/0.510
4zn7DESEstrogen receptor/0.510
1ysw43BApoptosis regulator Bcl-2/0.509
4kfj1R0Dihydrofolate reductase1.5.1.30.505
3c1xCKKHepatocyte growth factor receptor2.7.10.10.503
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.503
4iyg1HUStrictosidine synthase4.3.3.20.503
1efaNPFLactose operon repressor/0.502
1zgaHMKIsoflavone 4'-O-methyltransferase/0.502
2xkeWI2Serine/threonine-protein kinase Nek22.7.11.10.501
3nkt1HNGentisate 1,2-dioxygenase/0.501
4ivy1GTEstrogen receptor/0.501
4lgaA2OAbscisic acid receptor PYL2/0.501
1kmvLIIDihydrofolate reductase1.5.1.30.500
3i0rRT3Gag-Pol polyprotein2.7.7.490.500
1s9qOHTEstrogen-related receptor gamma/0.498
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.498
1jlcFTCGag-Pol polyprotein2.7.7.490.496
1yhoTRRDihydrofolate reductase1.5.1.30.496
1tl3H20Gag-Pol polyprotein2.7.7.490.495
1rkhVD2Vitamin D3 receptor/0.494
1mc5AHEAlcohol dehydrogenase class-31.1.1.10.493
1xj7DHTAndrogen receptor/0.491
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.491
2x7gPVBSRSF protein kinase 22.7.11.10.491
3c3dFO12-phospho-L-lactate transferase/0.491
1qtqQSIGlutamine--tRNA ligase6.1.1.180.490
1dajMOTDihydrofolate reductase1.5.1.30.489
1sr7MOFProgesterone receptor/0.489
3angDCCTranscriptional repressor, TetR family/0.489
3pdtADPMyosin heavy chain kinase A2.7.11.70.489
4hfnCIY2-alkenal reductase (NADP(+)-dependent)/0.489
1dr4HBIDihydrofolate reductase1.5.1.30.488
1qzfFOLBifunctional dihydrofolate reductase-thymidylate synthase/0.488
3dhbC6LN-acyl homoserine lactonase AiiA3.1.1.810.488
4iw8KN3Estrogen receptor/0.488
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.487
2pioDHTAndrogen receptor/0.487
1fbyREARetinoic acid receptor RXR-alpha/0.486
2acwUPGGlycosyltransferase/0.486
2p7zOHTEstrogen-related receptor gamma/0.486
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.486
3nxoD2BDihydrofolate reductase1.5.1.30.486
4kd79DRDihydrofolate reductase1.5.1.30.486
2gpuOHTEstrogen-related receptor gamma/0.485
2opxDXCLactaldehyde dehydrogenase1.2.1.220.485
3nxtD2EDihydrofolate reductase1.5.1.30.485
1ygjRMCPyridoxal kinase2.7.1.350.484
2jb4A14Isopenicillin N synthase1.21.3.10.484
2xf3J01Uncharacterized protein/0.484
4rujVDXVitamin D3 receptor A/0.484
1s6qTPBGag-Pol polyprotein2.7.7.490.483
1t7tDHTAndrogen receptor/0.483
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.483
2iyaZIOOleandomycin glycosyltransferase/0.483
2wqoVGKSerine/threonine-protein kinase Nek22.7.11.10.483
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.483
3ov4EQUSteroid Delta-isomerase5.3.3.10.483
5bukFADFADH2-dependent halogenase/0.483
3eigMTXDihydrofolate reductase1.5.1.30.482
3nj0PYVAbscisic acid receptor PYL2/0.482
3nxrD2DDihydrofolate reductase1.5.1.30.482
4g2i0VQVitamin D3 receptor/0.482
1zdwFLVPrenyltransferase/0.481
2cl5BIECatechol O-methyltransferase2.1.1.60.481
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.481
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.481
3kdiA8SAbscisic acid receptor PYL2/0.481
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.481
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.480
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.480
3c3eFO12-phospho-L-lactate transferase/0.480
3hf6LX0Tryptophan 5-hydroxylase 11.14.16.40.480
4bb3KKAIsopenicillin N synthase1.21.3.10.480
4k7aDHTAndrogen receptor/0.480
4kak06UDihydrofolate reductase1.5.1.30.480
1pxgPRFQueuine tRNA-ribosyltransferase2.4.2.290.479
2xvw9NRSerum albumin/0.479
3bfa9ODOdorant binding protein ASP1/0.479
4a33PS8Glycylpeptide N-tetradecanoyltransferase/0.479
4fnd3H9Enoyl-CoA hydratase/0.479
1umlFR4Adenosine deaminase3.5.4.40.478
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.478
2p1u4TNRetinoic acid receptor RXR-alpha/0.478
2xk3XK3Serine/threonine-protein kinase Nek22.7.11.10.478
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.478
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.478
4g1y0VOVitamin D3 receptor A/0.478
1hnvTBOGag-Pol polyprotein2.7.7.490.477
1ivsVAAValine--tRNA ligase6.1.1.90.477
1klkPMDDihydrofolate reductase1.5.1.30.477
1obnASVIsopenicillin N synthase1.21.3.10.477
1p0pBCHCholinesterase3.1.1.80.477
2fpcSCGStrictosidine synthase4.3.3.20.477
2gpvOHTEstrogen-related receptor gamma/0.477
2xk85R1Serine/threonine-protein kinase Nek22.7.11.10.477
3a4pDFQHepatocyte growth factor receptor2.7.10.10.477
3c14FOKAdenylate cyclase type 2/0.477
3c14FOKAdenylate cyclase type 5/0.477
4lwbQJ8Nitric oxide synthase oxygenase1.14.13.1650.477
4tx9AMZPhosphoribosyl isomerase A/0.477
1e26GPBDihydrofolate reductase1.5.1.30.476
1s19MC9Vitamin D3 receptor/0.476
1trgCB3Thymidylate synthase/0.476
2pklDHTAndrogen receptor/0.476
3cseN22Uncharacterized protein/0.476
3d73NBBPheromone-binding protein ASP1/0.476
3nmpPYVAbscisic acid receptor PYL2/0.476
3roeTHMNAD(P)H-hydrate epimerase5.1.99.60.476
4ap1NAPSteroid monooxygenase/0.476
4r09URIToll-like receptor 8/0.476
1e7aPFLSerum albumin/0.475
1ot7IU5Bile acid receptor/0.475
1pd8CO4Dihydrofolate reductase1.5.1.30.475
2l98STLTroponin C, slow skeletal and cardiac muscles/0.475
2o4rVD5Vitamin D3 receptor/0.475
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.475
3up0D7SaceDAF-12/0.475
3zkyWT4Isopenicillin N synthase1.21.3.10.475
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.475
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.474
1w22NHBHistone deacetylase 83.5.1.980.474
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.474
2pixDHTAndrogen receptor/0.474
2tscCB3Thymidylate synthase/0.474
3d75NBBPheromone-binding protein ASP1/0.474
3gcq1BUMitogen-activated protein kinase 14/0.474
3kb0A8SAbscisic acid receptor PYL2/0.474
3lfzADPUncharacterized protein MJ1225/0.474
3mec65BGag-Pol polyprotein2.7.7.490.474
3r4nFU5Heat shock protein HSP 90-alpha/0.474
3v0o4GWHisto-blood group ABO system transferase/0.474
3vt65YIVitamin D3 receptor/0.474
5bsrCOA4-coumarate--CoA ligase 26.2.1.120.474
1mvcBM6Retinoic acid receptor RXR-alpha/0.473
2c9ePIDPeridinin-chlorophyll a protein, high-salt form/0.473
2rjp886A disintegrin and metalloproteinase with thrombospondin motifs 43.4.24.820.473
3mhtSAHModification methylase HhaI2.1.1.370.473
3njoP2MAbscisic acid receptor PYR1/0.473
3nxyD2HDihydrofolate reductase1.5.1.30.473
3sgy06WDihydrofolate reductase1.5.1.30.473
4kebFOLDihydrofolate reductase1.5.1.30.473
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.473
1fk9EFZGag-Pol polyprotein2.7.7.490.472
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.472
2jfaRALEstrogen receptor/0.472
3b9oFMNAlkane monoxygenase/0.472
3erdDESEstrogen receptor/0.472
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.472
5ansRX87,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.472
1eetBFUGag-Pol polyprotein2.7.7.490.471
1w06W05Isopenicillin N synthase1.21.3.10.471
1ysiN3BBcl-2-like protein 1/0.471
2bakAQZMitogen-activated protein kinase 14/0.471
2bxqIMNSerum albumin/0.471
3c36KAIGlutamate receptor ionotropic, kainate 1/0.471
3l71AZOCytochrome b/0.471
3p9tTCLRepressor/0.471
4a9yAQZMitogen-activated protein kinase 14/0.471
4ddrMMVDihydrofolate reductase1.5.1.30.471
4dscA8SAbscisic acid receptor PYL3/0.471
4g20484Vitamin D3 receptor A/0.471
4i7fNVEGag-Pol polyprotein2.7.7.490.471
4lrrCF9Thymidylate synthase/0.471
4mhtSAHModification methylase HhaI2.1.1.370.471
1mvsDTMDihydrofolate reductase1.5.1.30.470
1s9pDESEstrogen-related receptor gamma/0.470
1tkxGWBGag-Pol polyprotein2.7.7.490.470
2gfsPQBMitogen-activated protein kinase 14/0.470
2qeiCXXNa(+):neurotransmitter symporter (Snf family)/0.470
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.470
3ntz3TZDihydrofolate reductase1.5.1.30.470
3tptADPSerine/threonine-protein kinase toxin HipA/0.470
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.470
4m2xTMQDihydrofolate reductase1.5.1.30.470
4mv4ACPBiotin carboxylase6.3.4.140.470
4nbb9CATerminal oxygenase component of carbazole/0.470
1lhvNOGSex hormone-binding globulin/0.469
1s9dAFBCytohesin-2/0.469
1s9dAFBADP-ribosylation factor 1/0.469
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.469
2ewpTXFEstrogen-related receptor gamma/0.469
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.469
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.469
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
3v1s0LHStrictosidine synthase4.3.3.20.469
3vt5YI2Vitamin D3 receptor/0.469
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.469
4k37SAMAnaerobic sulfatase-maturating enzyme1.8.980.469
5c1mCLRMu-type opioid receptor/0.469
5jtbZMAAdenosine receptor A2a/0.469
1ddtAPUDiphtheria toxin/0.468
1dnpMHFDeoxyribodipyrimidine photo-lyase4.1.99.30.468
1fuyFIPTryptophan synthase alpha chain/0.468
1s3uTQDDihydrofolate reductase1.5.1.30.468
1tvrTB9Gag-Pol polyprotein2.7.7.490.468
2piwDHTAndrogen receptor/0.468
2qgtEEDEstrogen receptor/0.468
2rh9IGPTryptophan synthase alpha chain/0.468
2wn6NDPADP-ribosyltransferase enzymatic component/0.468
2wo7ASVIsopenicillin N synthase1.21.3.10.468
2zbaZBATrichothecene 3-O-acetyltransferase/0.468
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.468
3lm4HPXCatechol 2,3-dioxygenase/0.468
3nr4PYVAbscisic acid receptor PYL2/0.468
3reoEUG(Iso)eugenol O-methyltransferase2.1.1.1460.468
3zze6XPHepatocyte growth factor receptor2.7.10.10.468
1bk0ACVIsopenicillin N synthase1.21.3.10.467
1p93DEXGlucocorticoid receptor/0.467
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.467
2g44T3OEstrogen receptor/0.467
2ydvNECAdenosine receptor A2a/0.467
3biz61EWee1-like protein kinase2.7.10.20.467
3zrbORCProgesterone receptor/0.467
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.467
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.467
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.467
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.467
4gr9372Ribosyldihydronicotinamide dehydrogenase [quinone]/0.467
4ifvT27Gag-Pol polyprotein2.7.7.490.467
4m6l21VDihydrofolate reductase1.5.1.30.467
1crbRTLRetinol-binding protein 1/0.466
1oc1ASVIsopenicillin N synthase1.21.3.10.466
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.466
1y4sADPChaperone protein HtpG/0.466
1zg32HIIsoflavone 4'-O-methyltransferase/0.466
2fzjDH3Dihydrofolate reductase1.5.1.30.466
2w3mFOLDihydrofolate reductase1.5.1.30.466
3bi6396Wee1-like protein kinase2.7.10.20.466
3d90NOGProgesterone receptor/0.466
3mb714ICasein kinase II subunit alpha2.7.11.10.466
3zkuHCVIsopenicillin N synthase1.21.3.10.466
4bwaN0BPyrrolysine--tRNA ligase/0.466
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.466
4g1z0VPVitamin D3 receptor A/0.466
4jv41ORcAMP-dependent protein kinase type I-alpha regulatory subunit/0.466
4lg5A1OAbscisic acid receptor PYL2/0.466
4p6wMOFGlucocorticoid receptor/0.466
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.466
1v79FR7Adenosine deaminase3.5.4.40.465
2hasC3OVitamin D3 receptor/0.465
2imfTOM2-hydroxychromene-2-carboxylate isomerase5.99.1.40.465
2z7gEH9Adenosine deaminase3.5.4.40.465
3a27SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.465
3h3sH15Collagen type IV alpha-3-binding protein/0.465
3zbx6XEHepatocyte growth factor receptor2.7.10.10.465
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.465
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.465
4lsjLSJGlucocorticoid receptor/0.465
1db1VDXVitamin D3 receptor/0.464
1uhhCZPAequorin-2/0.464
2hamC33Vitamin D3 receptor/0.464
2oaxSNLMineralocorticoid receptor/0.464
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.464
2qe4JJ3Estrogen receptor/0.464
2y60M8FIsopenicillin N synthase1.21.3.10.464
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.464
3c34KAIGlutamate receptor ionotropic, kainate 1/0.464
3c35KAIGlutamate receptor ionotropic, kainate 1/0.464
3di6PDZGag-Pol polyprotein2.7.7.490.464
3i9kNADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase3.2.2.60.464
3zraORBProgesterone receptor/0.464
3zy6GFBGDP-fucose protein O-fucosyltransferase 12.4.1.2210.464
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.464
4b6l9ZPSerine/threonine-protein kinase PLK32.7.11.210.464
4ihl1F514-3-3 protein zeta/delta/0.464
4nmbFADBifunctional protein PutA/0.464
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.464
1gs4ZK5Androgen receptor/0.463
1rk3VDXVitamin D3 receptor/0.463
2atiIHUGlycogen phosphorylase, liver form2.4.1.10.463
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
2on6IMHPurine nucleoside phosphorylase2.4.2.10.463
2pitDHTAndrogen receptor/0.463
3srrQ20Dihydrofolate reductase1.5.1.30.463
3zr7OR8Progesterone receptor/0.463
4a2jAS0Progesterone receptor/0.463
4hlwTESAndrogen receptor/0.463
4kbn25UDihydrofolate reductase1.5.1.30.463
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.462
1jlaTNKGag-Pol polyprotein2.7.7.490.462
1jlgUC1Gag-Pol polyprotein2.7.7.490.462
1pd9CO4Dihydrofolate reductase1.5.1.30.462
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.462
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.462
2o4jVD4Vitamin D3 receptor/0.462
2rd2QSIGlutamine--tRNA ligase6.1.1.180.462
2w6pOA4Biotin carboxylase6.3.4.140.462
3a783EVVitamin D3 receptor/0.462
3hv3R49Mitogen-activated protein kinase 14/0.462
3mlaJJZProbable nicotinate-nucleotide adenylyltransferase/0.462
3ojiPYVAbscisic acid receptor PYL3/0.462
4cdmFO1Deoxyribodipyrimidine photolyase/0.462
4g8cC6LAlpha/beta hydrolase fold protein/0.462
4gg70J8Hepatocyte growth factor receptor2.7.10.10.462
4jxxATPGlutamine--tRNA ligase6.1.1.180.462
4nbh9CATerminal oxygenase component of carbazole/0.462
4xe606UDihydrofolate reductase1.5.1.30.462
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.462
5iubCLRAdenosine receptor A2a/0.462
1felFENRetinol-binding protein 4/0.461
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.461
1hfqMOTDihydrofolate reductase1.5.1.30.461
1kmyBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.461
1qnfHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.461
1rkgVD1Vitamin D3 receptor/0.461
1rzuADPGlycogen synthase 12.4.1.210.461
1s3wTQTDihydrofolate reductase1.5.1.30.461
1t5zDHTAndrogen receptor/0.461
1ve3SAMUncharacterized protein/0.461
1ysx4EBSerum albumin/0.461
2bu9HFVIsopenicillin N synthase1.21.3.10.461
2owb626Serine/threonine-protein kinase PLK12.7.11.210.461
2wgjVGHHepatocyte growth factor receptor2.7.10.10.461
3akzGSUGlutamate--tRNA ligase 2/0.461
3b9lAZZSerum albumin/0.461
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.461
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.461
3eon341Glutaryl-CoA dehydrogenase/0.461
3ghwGHWDihydrofolate reductase1.5.1.30.461
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.461
3r336MEDihydrofolate reductase1.5.1.30.461
4g210VPVitamin D3 receptor A/0.461
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.461
4qjcIXEDihydrofolate reductase1.5.1.30.461
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.460
1fkoEFZGag-Pol polyprotein2.7.7.490.460
1hfrMOTDihydrofolate reductase1.5.1.30.460
1l2iETCEstrogen receptor/0.460
1ludTRRDihydrofolate reductase1.5.1.30.460
1lwlDSOCamphor 5-monooxygenase1.14.15.10.460
1t74DHTAndrogen receptor/0.460
1zprCB3Thymidylate synthase/0.460
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.460
2iwuNP5ATP-dependent molecular chaperone HSP82/0.460
2vdyHCYCorticosteroid-binding globulin/0.460
2w3vTOPDihydrofolate reductase/0.460
2xnpWCXSerine/threonine-protein kinase Nek22.7.11.10.460
2yac937Serine/threonine-protein kinase PLK12.7.11.210.460
2yatEEUEstrogen receptor/0.460
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.460
3bfb9ODPheromone-binding protein ASP1/0.460
3g07SAM7SK snRNA methylphosphate capping enzyme2.1.10.460
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.460
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.460
3s3vTOPDihydrofolate reductase1.5.1.30.460
3ubdSL0Ribosomal protein S6 kinase alpha-32.7.11.10.460
3vtcTK3Vitamin D3 receptor/0.460
4g8zTOPDihydrofolate reductase1.5.1.30.460
4pleCPSNuclear receptor subfamily 5 group A member 2/0.460
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.460
1hpzAAPGag-Pol polyprotein2.7.7.490.459
1n4hREANuclear receptor ROR-beta/0.459
1pq6965Oxysterols receptor LXR-beta/0.459
1qiqACCIsopenicillin N synthase1.21.3.10.459
1rt5UC2Gag-Pol polyprotein2.7.7.490.459
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.459
1x7e244Estrogen receptor/0.459
1xq3R18Androgen receptor/0.459
2ao6R18Androgen receptor/0.459
2piuDHTAndrogen receptor/0.459
2vagV25Dual specificity protein kinase CLK12.7.12.10.459
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.459
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.459
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
3cd2MTXDihydrofolate reductase1.5.1.30.459
3d80Q22Dihydrofolate reductase1.5.1.30.459
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.459
3mb601ICasein kinase II subunit alpha2.7.11.10.459
3nl1GTQGentisate 1,2-dioxygenase/0.459
3pffADPATP-citrate synthase2.3.3.80.459
3qly55VUncharacterized protein/0.459
1hniAAAGag-Pol polyprotein2.7.7.490.458
1mznBM6Retinoic acid receptor RXR-alpha/0.458
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.458
1t79DHTAndrogen receptor/0.458
1tkzH16Gag-Pol polyprotein2.7.7.490.458
1upw444Oxysterols receptor LXR-beta/0.458
1zy5ANPeIF-2-alpha kinase GCN2/0.458
2bf7HBIPteridine reductase 11.5.1.330.458
2hb8MVDVitamin D3 receptor/0.458
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.458
3e5aVX6Aurora kinase A2.7.11.10.458
3eem53VUncharacterized protein/0.458
3meeT27Gag-Pol polyprotein2.7.7.490.458
3ncz3NCRho-associated protein kinase 12.7.11.10.458
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.458
4fhh0U3Vitamin D3 receptor A/0.458
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.458
4myq19TcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.458
5dxgESTEstrogen receptor/0.458
1aq1STUCyclin-dependent kinase 22.7.11.220.457
1hb1OCVIsopenicillin N synthase1.21.3.10.457
1nhz486Glucocorticoid receptor/0.457
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.457
1x78244Estrogen receptor beta/0.457
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.457
2g1pSAHDNA adenine methylase2.1.1.720.457
2g8aUMPThymidylate synthase/0.457
2p1v5TNRetinoic acid receptor RXR-alpha/0.457
2q7lTESAndrogen receptor/0.457
2w8y486Progesterone receptor/0.457
2zd1T27Gag-Pol polyprotein2.7.7.490.457
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.457
3gyf51PDihydrofolate reductase1.5.1.30.457
3p8iFMNPentaerythritol tetranitrate reductase/0.457
3pqbVGPPutative oxidoreductase/0.457
3r6pA8SAbscisic acid receptor PYL10/0.457
3rg9WRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.457
3w0jT08Vitamin D3 receptor/0.457
4b1fKRHGlutamate racemase/0.457
4j6bPLOCytochrome P450 monooxygenase/0.457
4jlj1NMDeoxycytidine kinase2.7.1.740.457
5bt42LOBromodomain-containing protein 4/0.457
9mhtSAHModification methylase HhaI2.1.1.370.457
5k2aZMAAdenosine receptor A2a/0.457
3qakUKAAdenosine receptor A2a/0.457
1bozPRDDihydrofolate reductase1.5.1.30.456
1e3kR18Progesterone receptor/0.456
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1qjfACSIsopenicillin N synthase1.21.3.10.456
1tl1H18Gag-Pol polyprotein2.7.7.490.456
1vj3TABDihydrofolate reductase1.5.1.30.456
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.456
2ea2F77Methionine aminopeptidase 2/0.456
2fyuFDNCytochrome b/0.456
2oreSAHDNA adenine methylase2.1.1.720.456
2tdmUMPThymidylate synthase/0.456
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.456
2w3wVG9Dihydrofolate reductase/0.456
3fhxPXLPyridoxal kinase2.7.1.350.456
3gobHXXDdmC/0.456
3hucG97Mitogen-activated protein kinase 14/0.456
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.456
3l034OHEstrogen receptor/0.456
3m8p65BGag-Pol polyprotein2.7.7.490.456
3uvvREARetinoic acid receptor RXR-alpha/0.456
3vrvYSDVitamin D3 receptor/0.456
3w0c6DSVitamin D3 receptor/0.456
3w6hAZMCarbonic anhydrase 14.2.1.10.456
4gg50J3Hepatocyte growth factor receptor2.7.10.10.456
4rw6494Gag-Pol polyprotein2.7.7.490.456
4z9rNADOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.456
3reyXACAdenosine receptor A2a/0.456
1a4lDCFAdenosine deaminase3.5.4.40.455
1axwMTXThymidylate synthase/0.455
1ep4S11Gag-Pol polyprotein2.7.7.490.455
1kziTHGThymidylate synthase/0.455
1ndyFR3Adenosine deaminase3.5.4.40.455
1qruATPGlutamine--tRNA ligase6.1.1.180.455
1s0zEB1Vitamin D3 receptor/0.455
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
1xduSFGAclacinomycin 10-hydroxylase RdmB4.1.10.455
2cd2FOLDihydrofolate reductase1.5.1.30.455
2cjfRP43-dehydroquinate dehydratase4.2.1.100.455
2vbpVB1Isopenicillin N synthase1.21.3.10.455
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.455
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.455
3elm24FCollagenase 33.4.240.455
3kpzZNEVitamin D3 receptor/0.455
3qm4PN0Cytochrome P450 2D6/0.455
3vmmP0DAlanine--anticapsin ligase/0.455
3w0hW12Vitamin D3 receptor/0.455
3w5tLHPVitamin D3 receptor/0.455
3zqtTESAndrogen receptor/0.455
4bcmT7ZCyclin-dependent kinase 22.7.11.220.455
4c6zTLE3-oxoacyl-ACP synthase/0.455
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
4n1fCZHObelin/0.455
4rtkSAHDNA adenine methylase2.1.1.720.455
1cd2FOLDihydrofolate reductase1.5.1.30.454
1dr3HBIDihydrofolate reductase1.5.1.30.454
1f3eDPZQueuine tRNA-ribosyltransferase2.4.2.290.454
1jkhEFZGag-Pol polyprotein2.7.7.490.454
1kyzFERCaffeic acid 3-O-methyltransferase2.1.1.680.454
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.454
1r2jFADFkbI/0.454
1uyiPUZHeat shock protein HSP 90-alpha/0.454
1z4iUMP5'(3')-deoxyribonucleotidase, mitochondrial3.1.30.454
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
1zzlTZYMitogen-activated protein kinase 14/0.454
2c7qSAHModification methylase HhaI2.1.1.370.454
2pl0STITyrosine-protein kinase Lck2.7.10.20.454
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.454
2q7iTESAndrogen receptor/0.454
2qhxFE1Pteridine reductase 11.5.1.330.454
2w0hNDPTrypanothione reductase/0.454
2xveFADPutative flavin-containing monooxygenase/0.454
3at4CCKCasein kinase II subunit alpha2.7.11.10.454
3beaIXHMacrophage colony-stimulating factor 1 receptor2.7.10.10.454
3bgrT27Gag-Pol polyprotein2.7.7.490.454
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.454
3icpNADNAD-dependent epimerase/dehydratase/0.454
3nxvD2FDihydrofolate reductase1.5.1.30.454
3oiaA31Camphor 5-monooxygenase1.14.15.10.454
3sqyQ11Dihydrofolate reductase1.5.1.30.454
3ujlA8SAbscisic acid receptor PYL2/0.454
3v0p4GWHisto-blood group ABO system transferase/0.454
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4bgq38RCyclin-dependent kinase-like 52.7.11.220.454
4f700STCyclin-dependent kinase 82.7.11.220.454
4ia7BIVVitamin D3 receptor A/0.454
4oedDHTAndrogen receptor/0.454
4oicA8SBet v I allergen-like/0.454
5f2kSAHUncharacterized protein/0.454
1jf2CZHObelin/0.453
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.453
1lhuESTSex hormone-binding globulin/0.453
1th6OINBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.453
1tktH12Gag-Pol polyprotein2.7.7.490.453
2ban357Gag-Pol polyprotein2.7.7.490.453
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
2eauCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.453
2ftoCB3Thymidylate synthase/0.453
2opqHBQGag-Pol polyprotein2.7.7.490.453
2ov2GCPRas-related C3 botulinum toxin substrate 3/0.453
2puiADPMethylthioribose kinase2.7.1.1000.453
2r0pK2CPutative FAD-monooxygenase/0.453
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.453
2zshGA3Gibberellin receptor GID1A30.453
3c3ySAHO-methyltransferase/0.453
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.453
3dd125DGlycogen phosphorylase, liver form2.4.1.10.453
3ha3SAHHydroxymycolate synthase MmaA42.1.10.453
3ix4TX1Transcriptional activator protein LasR/0.453
3njoPYVAbscisic acid receptor PYR1/0.453
3pd3A3TThreonine--tRNA ligase6.1.1.30.453
3qlzQLZUncharacterized protein/0.453
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.453
4bcqTJFCyclin-dependent kinase 22.7.11.220.453
4c2wANPAurora kinase B-A2.7.11.10.453
4k38SAMAnaerobic sulfatase-maturating enzyme1.8.980.453
4twnB96Ephrin type-A receptor 32.7.10.10.453
1a50FIPTryptophan synthase alpha chain/0.452
1ikyMSDGag-Pol polyprotein2.7.7.490.452
1uy7PU4Heat shock protein HSP 90-alpha/0.452
1wdkACO3-ketoacyl-CoA thiolase/0.452
2az3CDPNucleoside diphosphate kinase/0.452
2bj4OHTEstrogen receptor/0.452
2cig1DGDihydrofolate reductase1.5.1.30.452
2f8pCEIObelin/0.452
2fzhDH1Dihydrofolate reductase1.5.1.30.452
2olcADPMethylthioribose kinase2.7.1.1000.452
2re8GSUGlutamine--tRNA ligase6.1.1.180.452
2vqoTFGHistone deacetylase 43.5.1.980.452
2w5bAGSSerine/threonine-protein kinase Nek22.7.11.10.452
2xk4OL2Serine/threonine-protein kinase Nek22.7.11.10.452
2zwaSAHtRNA wybutosine-synthesizing protein 42.1.1.2900.452
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.452
3ih0ANPUncharacterized sugar kinase PH14592.7.10.452
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3koo24DBifunctional epoxide hydrolase 23.3.2.100.452
3vrwYS5Vitamin D3 receptor/0.452
4at2ASDPossible succinate dehydrogenase/0.452
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.452
4fogC2FThymidylate synthase ThyA/0.452
4id5T27Gag-Pol polyprotein2.7.7.490.452
4s1iPLPPyridoxal kinase, putative/0.452
4u0mGTPCyclic GMP-AMP synthase/0.452
5cyqT27Gag-Pol polyprotein2.7.7.490.452
1errRALEstrogen receptor/0.451
1hfpMOTDihydrofolate reductase1.5.1.30.451
1sqi8694-hydroxyphenylpyruvate dioxygenase/0.451
1t7fDHTAndrogen receptor/0.451
1uyfPU1Heat shock protein HSP 90-alpha/0.451
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
2aaxPDNMineralocorticoid receptor/0.451
2hc4VDXVitamin D3 receptor A/0.451
2i0v6C3Macrophage colony-stimulating factor 1 receptor2.7.10.10.451
2iviACWIsopenicillin N synthase1.21.3.10.451
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.451
2zjwREFCasein kinase II subunit alpha2.7.11.10.451
3blrCPBCyclin-dependent kinase 92.7.11.220.451
3egvSAHRibosomal protein L11 methyltransferase2.1.10.451
3ekuCY9Actin-5C/0.451
3fhxPLPPyridoxal kinase2.7.1.350.451
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
3iw8HIZMitogen-activated protein kinase 14/0.451
3ko8NADNAD-dependent epimerase/dehydratase/0.451
3m6rBB2Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.451
3sm0AEKQueuine tRNA-ribosyltransferase2.4.2.290.451
4jlm1NNDeoxycytidine kinase2.7.1.740.451
4mrxCZHObelin/0.451
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.451
4zfn5GPPurine phosphoribosyltransferase (GpT-2)/0.451
5dx3ESTEstrogen receptor/0.451
5k0s0OUMethionine--tRNA ligase/0.451
4mqt2CUMuscarinic acetylcholine receptor M2/0.451
1dyrTOPDihydrofolate reductase1.5.1.30.450
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.450
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.450
1fmjRTLRetinol dehydratase/0.450
1g50ESTEstrogen receptor/0.450
1jg0DDTThymidylate synthase/0.450
1jujLYAThymidylate synthase2.1.1.450.450
1ly4COQDihydrofolate reductase1.5.1.30.450
1r6aSAHGenome polyprotein2.7.7.480.450
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
1tkaN3TTransketolase 12.2.1.10.450
1xngDNDNH(3)-dependent NAD(+) synthetase6.3.1.50.450
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.450
2b1z17MEstrogen receptor/0.450
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2bfpH4BPteridine reductase 11.5.1.330.450
2jkcFADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.450
2ovhAS0Progesterone receptor/0.450
2ph5NADHomospermidine synthase/0.450
2qe0NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase1.2.1.90.450
2w6oOA3Biotin carboxylase6.3.4.140.450
3aklADPSerine/threonine-protein kinase CtkA2.7.11.10.450
3d76NBBPheromone-binding protein ASP1/0.450
3gvuSTIAbelson tyrosine-protein kinase 22.7.10.20.450
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
3o8uBMUMitogen-activated protein kinase 14/0.450
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
3tq9MTXDihydrofolate reductase/0.450
3uudESTEstrogen receptor/0.450
4apuOR8Progesterone receptor/0.450
4bfvZVVPantothenate kinase2.7.1.330.450
4p5fAR6Inosine-uridine nucleoside N-ribohydrolase/0.450
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.450
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.450
4zasTYDCalS13/0.450
1aoeGW3Dihydrofolate reductase1.5.1.30.449
1blzACVIsopenicillin N synthase1.21.3.10.449
1kmsLIHDihydrofolate reductase1.5.1.30.449
1n5qTNCActVA 6 protein/0.449
1njaDCMThymidylate synthase/0.449
1rzy5ASHistidine triad nucleotide-binding protein 130.449
1vrqFONSubunit alpha of sarocosine oxidase/0.449
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.449
2ahvCOAAcetate CoA-transferase YdiF2.8.3.80.449
2fszOHTEstrogen receptor beta/0.449
2gblATPCircadian clock protein kinase KaiC2.7.11.10.449
2hl1A3SThreonine--tRNA ligase6.1.1.30.449
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.449
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.449
2vtqLZACyclin-dependent kinase 22.7.11.220.449
2watCOAFatty acid synthase subunit alpha2.3.1.860.449
2wggTLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.449
2y01Y00Beta-1 adrenergic receptor/0.449
2z2w770Wee1-like protein kinase2.7.10.20.449
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.449
3cqeP91Wee1-like protein kinase2.7.10.20.449
3gb4D3MDdmC/0.449
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.449
3q95ESLEstrogen receptor/0.449
3q9zTXQCasein kinase II subunit alpha2.7.11.10.449
3rm719ZCyclin-dependent kinase 22.7.11.220.449
3v49PK0Androgen receptor/0.449
3vi7CBDHematopoietic prostaglandin D synthase/0.449
4a8v2ANMajor pollen allergen Bet v 1-J/0.449
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.449
4gkt0O1Queuine tRNA-ribosyltransferase2.4.2.290.449
4h6pFMNChromate reductase/0.449
4ise1FWGlucokinase2.7.1.20.449
4kko1REGag-Pol polyprotein2.7.7.490.449
4l64C2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase2.1.1.140.449
4la7A1OAbscisic acid receptor PYL2/0.449
4qe6JN3Bile acid receptor/0.449
4rupH97Vitamin D3 receptor A/0.449
5k2cZMAAdenosine receptor A2a/0.449
1fkwPURAdenosine deaminase3.5.4.40.448
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.448
1mabADPATP synthase subunit beta, mitochondrial3.6.3.140.448
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.448
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.448
1t73DHTAndrogen receptor/0.448
2og81N8Tyrosine-protein kinase Lck2.7.10.20.448
2pogWSTEstrogen receptor/0.448
2pulACPMethylthioribose kinase2.7.1.1000.448
2vcmM11Isopenicillin N synthase1.21.3.10.448
2w3aTOPDihydrofolate reductase1.5.1.30.448
2yloTESAndrogen receptor/0.448
2zlcVDXVitamin D3 receptor/0.448
3bbfGDPNucleoside diphosphate kinase B2.7.4.60.448
3d0bSNXHeat shock protein HSP 90-alpha/0.448
3dmjGWEPol protein/0.448
3dr1C5DVitamin D3 receptor A/0.448
3oafOAGDihydrofolate reductase1.5.1.30.448
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.448
3qlxQLRUncharacterized protein/0.448
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.448
3sai9DRDihydrofolate reductase/0.448
3w0iO11Vitamin D3 receptor/0.448
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.448
3zoiM2WIsopenicillin N synthase1.21.3.10.448
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.448
4m8e29VRetinoic acid receptor RXR-alpha/0.448
4nieNBHNuclear receptor ROR-gamma/0.448
4ofrDHTAndrogen receptor/0.448
4ofuDHTAndrogen receptor/0.448
5iw4NADNADH pyrophosphatase/0.448
4ug2NGIAdenosine receptor A2a/0.448
1e3vDXCSteroid Delta-isomerase5.3.3.10.447
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
1fkxPRHAdenosine deaminase3.5.4.40.447
1nceCB3Thymidylate synthase/0.447
1og5SWFCytochrome P450 2C9/0.447
1sjwNGVNogalonic acid methyl ester cyclase/0.447
1t7rDHTAndrogen receptor/0.447
1tojHCIAspartate aminotransferase2.6.1.10.447
1uzwCDHIsopenicillin N synthase1.21.3.10.447
1x7jGENEstrogen receptor beta/0.447
2ab2SNLMineralocorticoid receptor/0.447
2b96ANNPhospholipase A23.1.1.40.447
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.447
2chlDKICasein kinase I isoform gamma-32.7.11.10.447
2gv8NDPThiol-specific monooxygenase1.14.130.447
2hndNVPGag-Pol polyprotein2.7.7.490.447
2ihuTP9N(2)-(2-carboxyethyl)arginine synthase/0.447
2rqfJH3Hemolymph juvenile hormone binding protein/0.447
2v58LZJBiotin carboxylase6.3.4.140.447
3bejMUFBile acid receptor/0.447
3dntATPSerine/threonine-protein kinase toxin HipA/0.447
3n0hTOPDihydrofolate reductase1.5.1.30.447
3nmhPYVAbscisic acid receptor PYL2/0.447
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.447
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.447
4hxs1A3Bromodomain-containing protein 4/0.447
4iv21GREstrogen receptor/0.447
4k6i9RARetinoic acid receptor RXR-alpha/0.447
4qa2SHHHistone deacetylase 83.5.1.980.447
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.447
4zp1TPPPyruvate decarboxylase4.1.1.10.447
1cqp803Integrin alpha-L/0.446
1dhfFOLDihydrofolate reductase1.5.1.30.446
1gs3EQUSteroid Delta-isomerase5.3.3.10.446
1ie8KH1Vitamin D3 receptor/0.446
1ohkCOPDihydrofolate reductase1.5.1.30.446
1s1vTNKGag-Pol polyprotein2.7.7.490.446
1uydPU8Heat shock protein HSP 90-alpha/0.446
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2d06ESTSulfotransferase 1A12.8.2.10.446
2fai459Estrogen receptor/0.446
2gsqGBIGlutathione S-transferase2.5.1.180.446
2hcdBIVVitamin D3 receptor A/0.446
2j62GSZO-GlcNAcase NagJ/0.446
2ociTYCValacyclovir hydrolase3.10.446
2pdlTOLAldose reductase1.1.1.210.446
2q7kTESAndrogen receptor/0.446
2uzbC75Cyclin-dependent kinase 22.7.11.220.446
2vz0D64Pteridine reductase/0.446
2zlaVDBVitamin D3 receptor/0.446
2zxbZXBAlpha-L-fucosidase, putative/0.446
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.446
3h0a9RARetinoic acid receptor RXR-alpha/0.446
3hy4N5G5-formyltetrahydrofolate cyclo-ligase6.3.3.20.446
3jq6DX1Pteridine reductase, putative/0.446
3kb3A8SAbscisic acid receptor PYL2/0.446
3lfcZ86Mitogen-activated protein kinase 14/0.446
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3nga3NGCasein kinase II subunit alpha2.7.11.10.446
3rmeRMEAcidic mammalian chitinase3.2.1.140.446
3td8D2RDihydrofolate reductase1.5.1.30.446
3vt3VDXVitamin D3 receptor/0.446
4bchT7ZCyclin-dependent kinase 92.7.11.220.446
4bmpFMNProtein NrdI/0.446
4c717RD3-oxoacyl-ACP synthase/0.446
4dm6TTBRetinoic acid receptor beta/0.446
4dymIYZActivin receptor type-12.7.11.300.446
4ej1FOLDihydrofolate reductase1.5.1.30.446
4ko0JLJGag-Pol polyprotein2.7.7.490.446
4v26TF3[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.446
1bq1CB3Thymidylate synthase/0.445
1e2jTHMThymidine kinase/0.445
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1gy3ATPCyclin-dependent kinase 22.7.11.220.445
1kt5RTLRetinol-binding protein 4/0.445
1pkdUCNCyclin-dependent kinase 22.7.11.220.445
1qjgEQUSteroid Delta-isomerase5.3.3.10.445
1rt4UC1Gag-Pol polyprotein2.7.7.490.445
1yy44NAEstrogen receptor beta/0.445
2j5sKTAAlr4455 protein/0.445
2uxhQUEHTH-type transcriptional regulator TtgR/0.445
2wqpWQPPolysialic acid capsule biosynthesis protein SiaC/0.445
2xjgXJGHeat shock protein HSP 90-alpha/0.445
3a60STURibosomal protein S6 kinase beta-12.7.11.10.445
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
3gn2AX8Pteridine reductase/0.445
3iogSDFMetallo-beta-lactamase type 2/0.445
3jziJZLBiotin carboxylase6.3.4.140.445
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.445
4b4w9L9Bifunctional protein FolD/0.445
4ea2RWZDehydrosqualene synthase/0.445
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.445
4fevPP1Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.445
4kvgGTPRas-related protein Rap-1A/0.445
4o71CPBBromodomain-containing protein 4/0.445
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.445
1dd6MCIMetallo-beta-lactamase type 2/0.444
1ej3CZHAequorin-2/0.444
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1hb3SCVIsopenicillin N synthase1.21.3.10.444
1ie9VDXVitamin D3 receptor/0.444
1jlqSBNGag-Pol polyprotein2.7.7.490.444
1ndzFR5Adenosine deaminase3.5.4.40.444
1rjkVDZVitamin D3 receptor/0.444
1t76DHTAndrogen receptor/0.444
1t7mDHTAndrogen receptor/0.444
2bfaCB3Pteridine reductase 11.5.1.330.444
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.444
2fk8SAMHydroxymycolate synthase MmaA42.1.10.444
2i9kSAHModification methylase HhaI2.1.1.370.444
2parTMP5'-deoxynucleotidase YfbR/0.444
2qjySMACytochrome b/0.444
2ylqTESAndrogen receptor/0.444
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3fgoACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.444
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
3nhyA7BRibosyldihydronicotinamide dehydrogenase [quinone]/0.444
3ns2PYVAbscisic acid receptor PYL2/0.444
3nu03TUDihydrofolate reductase1.5.1.30.444
3qx4X4BCyclin-dependent kinase 22.7.11.220.444
3vzdUULSphingosine kinase 12.7.1.910.444
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.444
4fgh0U6Dihydrofolate reductase1.5.1.30.444
4hxr1A4Bromodomain-containing protein 4/0.444
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.444
3rfmCFFAdenosine receptor A2a/0.444
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
1hvyD16Thymidylate synthase2.1.1.450.443
1kceCB3Thymidylate synthase/0.443
1kdmDHTSex hormone-binding globulin/0.443
1lcoPPYCytochrome b2, mitochondrial1.1.2.30.443
1mczTDPBenzoylformate decarboxylase4.1.1.70.443
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
1osvCHCBile acid receptor/0.443
1txiTX5Vitamin D3 receptor/0.443
1uymPU3Heat shock protein HSP 90-beta/0.443
1v7aFRCAdenosine deaminase3.5.4.40.443
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2o7pNAPRiboflavin biosynthesis protein RibD/0.443
2ofv242Tyrosine-protein kinase Lck2.7.10.20.443
2xlrFADPutative flavin-containing monooxygenase/0.443
2yelWSHBromodomain-containing protein 4/0.443
3bmqAX5Pteridine reductase/0.443
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.443
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3ffi3OBGag-Pol polyprotein2.7.7.490.443
3irxUDRGag-Pol polyprotein2.7.7.490.443
3qj5022Alcohol dehydrogenase class-31.1.1.10.443
3tm0ANPAminoglycoside 3'-phosphotransferase2.7.1.950.443
3vufADPGranule-bound starch synthase 1, chloroplastic/amyloplastic2.4.1.2420.443
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
4biwANPSensor histidine kinase CpxA/0.443
4c73TLH3-oxoacyl-ACP synthase/0.443
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.443
4cvbPQQAlcohol dehydrogenase/0.443
4g2h0VQVitamin D3 receptor A/0.443
4gbeSAHDNA adenine methylase2.1.1.720.443
4h3g10QBeta-secretase 13.4.23.460.443
4j7xSASSepiapterin reductase1.1.1.1530.443
4kfbT27Gag-Pol polyprotein2.7.7.490.443
4l0qNADAlcohol dehydrogenase class-3/0.443
4mk728OGenome polyprotein2.7.7.480.443
4qjqOTRLactoperoxidase/0.443
4wboANWRhodopsin kinase/0.443
3v2wML5Sphingosine 1-phosphate receptor 1/0.443
3emlZMAAdenosine receptor A2a/0.443
1af7SAHChemotaxis protein methyltransferase2.1.1.800.442
1d2sDHTSex hormone-binding globulin/0.442
1dnaCB3Thymidylate synthase/0.442
1eqbFFOSerine hydroxymethyltransferase2.1.2.10.442
1jxzBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.442
1rdtL79Retinoic acid receptor RXR-alpha/0.442
1rx8FOLDihydrofolate reductase1.5.1.30.442
1s0xC3SNuclear receptor ROR-alpha/0.442
1u72MTXDihydrofolate reductase1.5.1.30.442
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
1vruAAPGag-Pol polyprotein2.7.7.490.442
1yimCM4Estrogen receptor/0.442
1zrqNAI5,10-methylenetetrahydrofolate reductase1.5.1.200.442
2dhfDZFDihydrofolate reductase1.5.1.30.442
2fziDH3Dihydrofolate reductase1.5.1.30.442
2gcpGSPRho-related GTP-binding protein RhoC/0.442
2giuFBREstrogen receptor beta/0.442
2hpsCTZCa2+-triggered coelenterazine-binding protein 1/0.442
2j9gADPBiotin carboxylase6.3.4.140.442
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.442
2jn3JN3Fatty acid-binding protein, liver/0.442
2oalFADFlavin-dependent tryptophan halogenase RebH1.14.19.90.442
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.442
2wkyIBCGlutamate receptor ionotropic, kainate 1/0.442
2xvfFADPutative flavin-containing monooxygenase/0.442
2zl9VDAVitamin D3 receptor/0.442
3be9P04Casein kinase II subunit alpha2.7.11.10.442
3bmnAX3Pteridine reductase/0.442
3fowIMHPurine nucleoside phosphorylase/0.442
3gyaCOAGCN5-related N-acetyltransferase/0.442
3i8aN22Dihydrofolate reductase1.5.1.30.442
3ipq965Oxysterols receptor LXR-alpha/0.442
3k47D09Dihydrofolate reductase1.5.1.30.442
3llaACPMyosin heavy chain kinase A2.7.11.70.442
3o9lLPNRenin3.4.23.150.442
3t1a5MAGag-Pol polyprotein2.7.7.490.442
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.442
3vtdTKDVitamin D3 receptor/0.442
4af3VX6Aurora kinase B2.7.11.10.442
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4au7SAHHistone-lysine N-methyltransferase KMT5C2.1.1.430.442
4g1d0VKVitamin D3 receptor A/0.442
4h4m494Gag-Pol polyprotein2.7.7.490.442
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4hni16WCasein kinase I isoform epsilon2.7.11.10.442
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.442
4itfTFYVitamin D3 receptor/0.442
4jlt8PRCytochrome P450 2B41.14.14.10.442
4jxzATPGlutamine--tRNA ligase6.1.1.180.442
4mv3ACPBiotin carboxylase6.3.4.140.442
4wctFADFructosyl amine:oxygen oxidoreductase/0.442
4wevSUZAldo-keto reductase family 1 member B101.1.10.442
5dr6SKEAurora kinase A2.7.11.10.442
6cp4CAMCamphor 5-monooxygenase1.14.15.10.442
1e7wMTXPteridine reductase 11.5.1.330.441
1knpFADL-aspartate oxidase1.4.3.160.441
1mewXMPInosine-5'-monophosphate dehydrogenase/0.441
1qknRALEstrogen receptor beta/0.441
1rt2TNKGag-Pol polyprotein2.7.7.490.441
1w29TS06,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
2ab8ACPAdenosine kinase2.7.1.200.441
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.441
2harOCCVitamin D3 receptor/0.441
2ocfESTEstrogen receptor/0.441
2ojg19AMitogen-activated protein kinase 12.7.11.240.441
2v57PRLTetR family transcriptional regulator/0.441
2werRDCATP-dependent molecular chaperone HSP82/0.441
2yjaESTEstrogen receptor/0.441
2ykjYKJHeat shock protein HSP 90-alpha/0.441
3bqdDAYGlucocorticoid receptor/0.441
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.441
3freTOPDihydrofolate reductase1.5.1.30.441
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3kdjA8SAbscisic acid receptor PYL1/0.441
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
3rl35GPMetallophosphoesterase MPPED23.10.441
3tq8TOPDihydrofolate reductase/0.441
4a99MIYTetX family tetracycline inactivation enzyme/0.441
4a9e3PFBromodomain-containing protein 2/0.441
4b8mVX6Aurora kinase B-A2.7.11.10.441
4fps0UXQueuine tRNA-ribosyltransferase2.4.2.290.441
4giy0WYQueuine tRNA-ribosyltransferase2.4.2.290.441
4golSA8DNA adenine methylase2.1.1.720.441
4hnc0UTMandelate racemase/0.441
4hneADPPhosphatidylinositol 4-kinase type 2-alpha/0.441
4jln18VDeoxycytidine kinase2.7.1.740.441
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4oezDHTAndrogen receptor/0.441
4uogYYYNucleoside diphosphate kinase/0.441
4zvmDM2Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
5mhtSAHModification methylase HhaI2.1.1.370.441
5g53NECAdenosine receptor A2a/0.441
1a5sFIPTryptophan synthase alpha chain/0.440
1k0aGTXTranscriptional regulator URE2/0.440
1kv2B96Mitogen-activated protein kinase 14/0.440
1lrhNLAAuxin-binding protein 1/0.440
1m78CLZDihydrofolate reductase1.5.1.30.440
1qrtATPGlutamine--tRNA ligase6.1.1.180.440
1sqnNDRProgesterone receptor/0.440
1srjNABStreptavidin/0.440
1tsdF89Thymidylate synthase/0.440
1xowR18Androgen receptor/0.440
1xp1AIHEstrogen receptor/0.440
2a4xBLMMitomycin-binding protein/0.440
2ag0TPPBenzaldehyde lyase/0.440
2j9lATPH(+)/Cl(-) exchange transporter 5/0.440
2r2mI50Prothrombin3.4.21.50.440
2vmyFFOSerine hydroxymethyltransferase/0.440
2vr0HQOCytochrome c-type protein/0.440
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3eej53RUncharacterized protein/0.440
3gi2GHWDihydrofolate reductase1.5.1.30.440
3i0sRT7Gag-Pol polyprotein2.7.7.490.440
3jq8DX3Pteridine reductase, putative/0.440
3megT27Gag-Pol polyprotein2.7.7.490.440
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3nmvPYVAbscisic acid receptor PYL2/0.440
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.440
3q2mCKISpectinomycin phosphotransferase/0.440
3qzyFADFAD-linked sulfhydryl oxidase/0.440
3rinI2OMitogen-activated protein kinase 14/0.440
3srsM23Dihydrofolate reductase1.5.1.30.440
3t0kDCQSulfide-quinone reductase/0.440
3tdl11DSerum albumin/0.440
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.440
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.440
3zrbOR8Progesterone receptor/0.440
4a9iP9IBromodomain-containing protein 2/0.440
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.440
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
4f1oACPProbable serine/threonine-protein kinase roco42.7.11.10.440
4g1qT27Gag-Pol polyprotein2.7.7.490.440
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4ig3T27Gag-Pol polyprotein2.7.7.490.440
4j3lAJ5Tankyrase-22.4.2.300.440
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.440
4jdaA9SAbscisic acid receptor PYL3/0.440
4mubOAQSulfotransferase oxamniquine resistance protein/0.440
4nqgCZHMitrocomin/0.440
7mhtSAHModification methylase HhaI2.1.1.370.440