sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Macrophage colony-stimulating factor 1 receptor
ID:	CSF1R_HUMAN
AC:	P07333
Organism:	Homo sapiens
Reign:	Eukaryota
TaxID:	9606
EC Number:	2.7.10.1

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Chains:

Chain Name:	Percentage of Residues within binding site
A	100 %

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Ligand binding site composition:

B-Factor:	22.735
Number of residues:	35
Including
Standard Amino Acids:	34
Non Standard Amino Acids:	0
Water Molecules:	1
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
0.543	334.125

% Hydrophobic	% Polar
54.55	45.45
According to VolSite

HET Code:	IXH
Formula:	C29H32N7O2
Molecular weight:	510.610 g/mol
DrugBank ID:	-
Buried Surface Area:	54.8 %
Polar Surface area:	121.06 Å2

Number of
H-Bond Acceptors:	7
H-Bond Donors:	3
Rings:	6
Aromatic rings:	3
Anionic atoms:	0
Cationic atoms:	1
Rule of Five Violation:	1
Rotatable Bonds:	5

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Mass center Coordinates

X	Y	Z
5.04061	28.7956	6.1385

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