Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4fuj | 1U9 | Urokinase-type plasminogen activator | 3.4.21.73 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4fuj | 1U9 | Urokinase-type plasminogen activator | 3.4.21.73 | 1.000 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.647 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.643 | |
| 4fud | 6UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.528 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.524 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.524 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.518 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.512 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.511 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.508 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.507 | |
| 4jic | FMN | GTN Reductase | / | 0.507 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.507 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.504 | |
| 1w13 | SM1 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.504 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.504 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.501 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.500 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.500 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.498 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.497 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.496 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.496 | |
| 4nvk | 2NY | Peroxidase | / | 0.496 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.496 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.495 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.495 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.494 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.494 | |
| 1u6q | 745 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.493 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.493 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.492 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.491 | |
| 1vja | 7IN | Urokinase-type plasminogen activator | 3.4.21.73 | 0.491 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.491 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.491 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.491 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.491 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.491 | |
| 1owk | 303 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.490 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.490 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.489 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.489 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.489 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.488 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.488 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.488 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.488 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.488 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.487 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.486 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.486 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.486 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.486 | |
| 1owd | 497 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.485 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.485 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.485 | |
| 3a3g | DLZ | Lumazine protein | / | 0.485 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.484 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.484 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.484 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.484 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.483 | |
| 1owi | 426 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.483 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.483 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.483 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.482 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.482 | |
| 4e2d | FMN | Dehydrogenase | / | 0.482 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.482 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.482 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.481 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.481 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.481 | |
| 4fub | 4UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.481 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.481 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.480 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.480 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.480 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.480 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.480 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.480 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.480 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.480 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.480 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.480 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.479 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.479 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.479 | |
| 3iqg | ASN_TRP_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.479 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.479 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.478 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.478 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.478 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.478 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.478 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.478 | |
| 3u9e | COA | Lmo1369 protein | / | 0.478 | |
| 4kgn | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.478 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.478 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.477 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.477 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.477 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.477 | |
| 4fdu | IHS | Putative multiple inositol polyphosphate histidine phosphatase 1 | / | 0.477 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.477 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.477 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.476 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.476 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.476 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.476 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.475 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.475 | |
| 3ens | ENS | Coagulation factor X | 3.4.21.6 | 0.475 | |
| 3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.475 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.475 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.474 | |
| 2g00 | 4QC | Coagulation factor X | 3.4.21.6 | 0.474 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.474 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.474 | |
| 4de1 | 0J6 | Beta-lactamase | / | 0.474 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.474 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.474 | |
| 1f92 | UKP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.473 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.473 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.473 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.473 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.473 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.473 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.473 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.473 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.472 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.472 | |
| 2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.472 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.472 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.472 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.472 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.472 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.472 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.471 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.471 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.471 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.471 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.471 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.471 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 4bti | 7R9 | Coagulation factor X | 3.4.21.6 | 0.471 | |
| 4fuf | 8UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.471 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.471 | |
| 5ftf | ADP | TPR domain protein | / | 0.471 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.470 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.470 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.470 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.470 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.470 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.470 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.470 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.470 | |
| 4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.470 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.470 | |
| 5cyo | GDP | Septin-9 | / | 0.470 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.469 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.469 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.469 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.469 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.469 | |
| 4bvb | AR6 | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.469 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.469 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.469 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.469 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.469 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.468 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 2dsg | SAH | Diphthine synthase | / | 0.468 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.468 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.467 | |
| 1ds7 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.467 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.467 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.467 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.467 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.467 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.467 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.467 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.467 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.467 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.467 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.467 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.466 | |
| 1nj6 | A5A | Proline--tRNA ligase | / | 0.466 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.466 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.466 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 3d2p | COA | Amino-acid acetyltransferase | / | 0.466 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.466 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.466 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.466 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.466 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 4blr | UTP | NTPase P4 | / | 0.466 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.465 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.465 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.465 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.465 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.465 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.465 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.465 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.465 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.465 | |
| 4e2b | FMN | Dehydrogenase | / | 0.465 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.465 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.464 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.464 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.464 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.464 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.464 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.464 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.464 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.464 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.464 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.464 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.464 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.463 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.463 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.463 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.463 | |
| 3v2u | ATP | Protein GAL3 | / | 0.463 | |
| 4btt | VYR | Coagulation factor X | 3.4.21.6 | 0.463 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.463 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.463 | |
| 1aj2 | 2PH | Dihydropteroate synthase | / | 0.462 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.462 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.462 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.462 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.462 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.462 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.462 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.462 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.462 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.462 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.461 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.461 | |
| 1sdm | ADP | Kinesin heavy chain-like protein | / | 0.461 | |
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.461 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.461 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.461 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.461 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.461 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.461 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.461 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.461 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.461 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.461 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.461 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.461 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.461 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.461 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.461 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.461 | |
| 5a1t | NAI | L-lactate dehydrogenase | / | 0.461 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.460 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.460 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.460 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.460 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.460 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2iiq | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.460 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.460 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.460 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.460 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.460 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.460 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.460 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.460 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.460 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.460 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.459 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.459 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.459 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.459 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.459 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.459 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.459 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.459 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.459 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.459 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.459 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.459 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.459 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.459 | |
| 4qec | NAP | ElxO | / | 0.459 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.458 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.458 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.458 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.458 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.458 | |
| 3ieu | GDP | GTPase Era | / | 0.458 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.458 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.458 | |
| 3ut5 | LOC | Tubulin beta chain | / | 0.458 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.458 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.458 | |
| 4xbo | SAH | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.1.1.200 | 0.458 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.457 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1mbb | EEB | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.457 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.457 | |
| 2ejz | SAH | Diphthine synthase | / | 0.457 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.457 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.457 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.457 | |
| 3ivx | FG6 | Pantothenate synthetase | 6.3.2.1 | 0.457 | |
| 3zhb | NAP | Putative dehydrogenase | / | 0.457 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.457 | |
| 4hmx | FMN | Pyridoxamine 5'-phosphate oxidase | / | 0.457 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.457 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.457 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1i5e | U5P | Uracil phosphoribosyltransferase | / | 0.456 | |
| 1ja0 | NAP | NADPH--cytochrome P450 reductase | / | 0.456 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.456 | |
| 1sqt | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.456 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.456 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.456 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.456 | |
| 2e07 | SAH | Diphthine synthase | / | 0.456 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.456 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.456 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.456 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3r96 | ACO | MccE protein | / | 0.456 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.456 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 4e31 | JHZ | Methyltransferase | / | 0.456 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.456 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.456 | |
| 5c41 | ACP | Ribokinase | / | 0.456 | |
| 1bp6 | UMP | Thymidylate synthase | / | 0.455 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1dj2 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.455 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.455 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.455 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.455 | |
| 2cji | GSK | Coagulation factor X | 3.4.21.6 | 0.455 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.455 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.455 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.455 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.455 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.455 | |
| 4btu | 6XS | Coagulation factor X | 3.4.21.6 | 0.455 | |
| 4e2y | JHZ | Methyltransferase | / | 0.455 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.455 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.455 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.454 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.454 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.454 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.454 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.454 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.454 | |
| 2p6d | SAH | Diphthine synthase | / | 0.454 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.454 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.454 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.454 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3ov7 | ATP | CCA-adding enzyme | 2.7.7.72 | 0.454 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.454 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.454 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.454 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.454 | |
| 5a3c | NAD | SIR2 family protein | / | 0.454 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.453 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.453 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.453 | |
| 1jil | 485 | Tyrosine--tRNA ligase | / | 0.453 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.453 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.453 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1wng | SAH | Diphthine synthase | / | 0.453 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.453 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.453 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.453 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.453 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.453 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.453 | |
| 3ivm | ZPR | Prolyl endopeptidase | / | 0.453 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.453 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.453 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.453 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.453 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.453 | |
| 4wzh | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.453 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.452 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1o6z | NAD | Malate dehydrogenase | / | 0.452 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.452 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.452 | |
| 2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.452 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.452 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.452 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.452 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.452 | |
| 3i25 | MV7 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.452 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 3zpo | K0I | Histone demethylase UTY | 1.14.11 | 0.452 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.452 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.452 | |
| 4irn | FAD | AnaB | / | 0.452 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.452 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.452 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.452 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.452 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.452 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.452 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.452 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.451 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.451 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.451 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.451 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.451 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.451 | |
| 2pck | SAH | Diphthine synthase | / | 0.451 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.451 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.451 | |
| 2y5h | Y5H | Coagulation factor X | 3.4.21.6 | 0.451 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.451 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.451 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.451 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.451 | |
| 3s2v | 3HU | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4ha9 | NDP | 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase | 1.1.1.302 | 0.451 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.451 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.451 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.450 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.450 | |
| 1v5z | 2HC | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.450 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.450 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.450 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.450 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.450 | |
| 3ing | NDP | Homoserine dehydrogenase related protein | / | 0.450 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.450 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.450 | |
| 3rfa | SAM | Dual-specificity RNA methyltransferase RlmN | / | 0.450 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.450 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.450 | |
| 4e32 | DWN | Methyltransferase | / | 0.450 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.450 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.450 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.450 | |
| 4ple | CPS | Nuclear receptor subfamily 5 group A member 2 | / | 0.450 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.450 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1ri3 | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.449 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.449 | |
| 2eka | SAH | Diphthine synthase | / | 0.449 | |
| 2emu | SAH | Diphthine synthase | / | 0.449 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.449 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.449 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.449 | |
| 2xfi | XFI | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.449 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.449 | |
| 3n4k | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.449 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.449 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 4hms | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.449 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.449 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.449 | |
| 5b0o | ADP | Flagellum-specific ATP synthase | 3.6.3.14 | 0.449 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.448 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1ri4 | SAM | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.448 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.448 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.448 | |
| 2e15 | SAH | Diphthine synthase | / | 0.448 | |
| 2emr | SAH | Diphthine synthase | / | 0.448 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.448 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.448 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.448 | |
| 2owk | SAH | Diphthine synthase | / | 0.448 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 2wsi | FAD | FAD synthase | 2.7.7.2 | 0.448 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.448 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.448 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.448 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.448 | |
| 3o7b | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | / | 0.448 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.448 | |
| 3wag | TYD | Glycosyltransferase | / | 0.448 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.448 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.448 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.447 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.447 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.447 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.447 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.447 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.447 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.447 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.447 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2yy8 | SAM | tRNA (cytidine(56)-2'-O)-methyltransferase | / | 0.447 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.447 | |
| 3l5l | FMN | Xenobiotic reductase | / | 0.447 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.447 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.447 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.447 | |
| 4u0m | ATP | Cyclic GMP-AMP synthase | / | 0.447 | |
| 4wxx | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.447 | |
| 4yqf | GDP | Septin-9 | / | 0.447 | |
| 1b5t | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.446 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.446 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.446 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.446 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.446 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.446 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.446 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.446 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.446 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.446 | |
| 3lu1 | UD2 | UDP-N-acetylglucosamine 4-epimerase | / | 0.446 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.446 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4rel | KMP | Glycosyltransferase | / | 0.446 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.446 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1i6x | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.445 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.445 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.445 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.445 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.445 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.445 | |
| 2rir | NAP | Dipicolinate synthase subunit A | / | 0.445 | |
| 2vht | ATP | NTPase P4 | / | 0.445 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.445 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.445 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.445 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.445 | |
| 3khu | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.445 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.445 | |
| 3zhy | FM6 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.445 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.445 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.445 | |
| 4rvd | SAM | D-mycarose 3-C-methyltransferase | / | 0.445 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.445 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.445 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.444 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.444 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.444 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.444 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.444 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 1udc | UFM | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.444 | |
| 2e17 | SAH | Diphthine synthase | / | 0.444 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.444 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.444 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.444 | |
| 3lcj | COA | Phosphopantetheine adenylyltransferase | / | 0.444 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.444 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.444 | |
| 3udk | 095 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.444 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.444 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 4eu4 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.444 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.444 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.444 | |
| 4x9m | FAD | Uncharacterized protein MG039 homolog | / | 0.444 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.444 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.444 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.444 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.444 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1ty9 | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.443 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.443 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.443 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.443 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.443 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.443 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.443 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.443 | |
| 3b2e | ADP | ATPase GET3 | / | 0.443 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.443 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.443 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.443 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.443 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.443 | |
| 3q70 | RIT | Candidapepsin-2 | 3.4.23.24 | 0.443 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.443 | |
| 4b70 | WM9 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.443 | |
| 4er6 | AW2 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.443 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.443 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.443 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.443 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.442 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.442 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1hon | GNH | Adenylosuccinate synthetase | / | 0.442 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.442 | |
| 1l5s | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.442 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.442 | |
| 1w51 | L01 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.442 | |
| 1zji | 2PG | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.442 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.442 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.442 | |
| 2ehl | SAH | Diphthine synthase | / | 0.442 | |
| 2ele | SAH | Diphthine synthase | / | 0.442 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.442 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2q14 | ADP | Phosphohydrolase | / | 0.442 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.442 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.442 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.442 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.442 | |
| 3beo | UD1 | UDP-N-acetylglucosamine 2-epimerase | / | 0.442 | |
| 3dm5 | GDP | Signal recognition particle 54 kDa protein | / | 0.442 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.442 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 3pft | FMN | Flavin reductase | / | 0.442 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 3pnd | FAD | FAD:protein FMN transferase | / | 0.442 | |
| 4a30 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.442 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.442 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.442 | |
| 4jpe | 1M7 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.442 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.442 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.442 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.442 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.441 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.441 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.441 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1mq6 | XLD | Coagulation factor X | 3.4.21.6 | 0.441 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 1nj5 | P5A | Proline--tRNA ligase | / | 0.441 | |
| 1nly | AGS | Cag alpha | / | 0.441 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.441 | |
| 1pvg | ANP | DNA topoisomerase 2 | 5.99.1.3 | 0.441 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 2dek | SAH | Diphthine synthase | / | 0.441 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.441 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.441 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.441 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.441 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.441 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.441 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3wid | NAP | Glucose 1-dehydrogenase | / | 0.441 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.441 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.441 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.441 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.441 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.441 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.441 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.441 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.441 | |
| 8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1a9s | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1daa | PLP | D-alanine aminotransferase | 2.6.1.21 | 0.440 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.440 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.440 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.440 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.440 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.440 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.440 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 2bkj | FMN | NADPH-flavin oxidoreductase | / | 0.440 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.440 | |
| 2dxw | SAH | Diphthine synthase | / | 0.440 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.440 | |
| 2ha8 | SAH | Probable methyltransferase TARBP1 | / | 0.440 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.440 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.440 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3mtw | M3R | Xaa-Pro dipeptidase, putative | / | 0.440 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.440 | |
| 3t7s | SAM | Uncharacterized protein | / | 0.440 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.440 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.440 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.440 |