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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fuj1U9Urokinase-type plasminogen activator3.4.21.73

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4fuj1U9Urokinase-type plasminogen activator3.4.21.731.000
4fue7UPUrokinase-type plasminogen activator3.4.21.730.647
4fuiUI3Urokinase-type plasminogen activator3.4.21.730.643
4fud6UPUrokinase-type plasminogen activator3.4.21.730.528
2iyfERYOleandomycin glycosyltransferase2.4.10.524
3qt62P0Mevalonate diphosphate decarboxylase/0.524
2rlcCHDCholoylglycine hydrolase3.5.1.240.518
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.512
1o9bNAIQuinate/shikimate dehydrogenase/0.511
3h06VBPGlutamate receptor 2/0.508
1xe55FEPlasmepsin-23.4.23.390.507
4jicFMNGTN Reductase/0.507
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.507
1tqf32PBeta-secretase 13.4.23.460.504
1w13SM1Urokinase-type plasminogen activator3.4.21.730.504
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.504
2ii6C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.501
2f3rG5PGuanylate kinase2.7.4.80.500
2hfuMEVMevalonate kinase/0.500
3p67FMNPentaerythritol tetranitrate reductase/0.498
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.497
1h50FMNPentaerythritol tetranitrate reductase/0.496
1owe675Urokinase-type plasminogen activator3.4.21.730.496
4nvk2NYPeroxidase/0.496
4w5kPLPAspartate aminotransferase, mitochondrial/0.496
2vkeTACTetracycline repressor protein class D/0.495
3f03FMNPentaerythritol tetranitrate reductase/0.495
1xe65FPPlasmepsin-23.4.23.390.494
2gv8NDPThiol-specific monooxygenase1.14.130.494
1u6q745Urokinase-type plasminogen activator3.4.21.730.493
1w6hTITPlasmepsin-23.4.23.390.493
1h51FMNPentaerythritol tetranitrate reductase/0.492
1h63FMNPentaerythritol tetranitrate reductase/0.491
1vja7INUrokinase-type plasminogen activator3.4.21.730.491
2a94AP0L-lactate dehydrogenase1.1.1.270.491
3b6zCO7Enoyl reductase LovC10.491
3gkaFMNN-ethylmaleimide reductase/0.491
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.491
4k28NADShikimate dehydrogenase family protein/0.491
1owk303Urokinase-type plasminogen activator3.4.21.730.490
3ctyFADProbable thioredoxin reductase/0.490
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.489
3gqvNAPEnoyl reductase LovC10.489
4kbyC2EStimulator of interferon genes protein/0.489
1umaIN2Prothrombin3.4.21.50.488
1x1cSAHC-20 methyltransferase/0.488
3clsFADElectron transfer flavoprotein subunit alpha/0.488
3q9bB3NAcetylpolyamine amidohydrolase/0.488
3t4eNADQuinate/shikimate dehydrogenase/0.488
3b70NAPEnoyl reductase LovC10.487
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.486
3dm6757Beta-secretase 13.4.23.460.486
3lqsPSZD-alanine aminotransferase2.6.1.210.486
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.486
1owd497Urokinase-type plasminogen activator3.4.21.730.485
1w34FADFerredoxin--NADP reductase1.18.1.20.485
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.485
3a3gDLZLumazine protein/0.485
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.484
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.484
2ylrNAPPhenylacetone monooxygenase1.14.13.920.484
4df2FMNNADPH dehydrogenase/0.484
1g1aNADdTDP-glucose 4,6-dehydratase/0.483
1owi426Urokinase-type plasminogen activator3.4.21.730.483
3iocA5DPantothenate synthetase6.3.2.10.483
4b1rITCTetracycline repressor protein class D/0.483
3tjlFMNNADPH dehydrogenase/0.482
4dx7DM2Multidrug efflux pump subunit AcrB/0.482
4e2dFMNDehydrogenase/0.482
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.482
4opgFDAConserved Archaeal protein/0.482
2dftADPShikimate kinase2.7.1.710.481
3a1nNADNDP-sugar epimerase/0.481
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.481
4fub4UPUrokinase-type plasminogen activator3.4.21.730.481
4m83ERYOleandomycin glycosyltransferase2.4.10.481
1cnfFADNitrate reductase [NADH]1.7.1.10.480
1nfyRTRCoagulation factor X3.4.21.60.480
1xvaSAMGlycine N-methyltransferase2.1.1.200.480
2fj1CTCTetracycline repressor protein class D/0.480
2oapANPType II secretion system protein (GspE-2)/0.480
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.480
3fhxPLPPyridoxal kinase2.7.1.350.480
3vg10GTBeta-secretase 13.4.23.460.480
3zeiAWHO-acetylserine sulfhydrylase/0.480
4de2DN3Beta-lactamase/0.480
4kgkGTPUncharacterized protein/0.480
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.479
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.479
2cy0NAPShikimate dehydrogenase (NADP(+))/0.479
3iqgASN_TRP_ASN_ILECysteine synthase2.5.1.470.479
3kpbSAMUncharacterized protein MJ0100/0.479
1gpuTHDTransketolase 12.2.1.10.478
1npdNADQuinate/shikimate dehydrogenase/0.478
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.478
1rkwPNTHTH-type transcriptional regulator QacR/0.478
1szgFNSCytochrome b2, mitochondrial1.1.2.30.478
2cndFADNitrate reductase [NADH]1.7.1.10.478
3u9eCOALmo1369 protein/0.478
4kgnSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.478
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.478
1h73ANPHomoserine kinase2.7.1.390.477
2abbFMNPentaerythritol tetranitrate reductase/0.477
2vyqFADFerredoxin--NADP reductase1.18.1.20.477
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.477
3p62FMNPentaerythritol tetranitrate reductase/0.477
3tjzGNPADP-ribosylation factor 1/0.477
4fduIHSPutative multiple inositol polyphosphate histidine phosphatase 1/0.477
4h1e10JBeta-secretase 13.4.23.460.477
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.477
5d3qGDPDynamin-13.6.5.50.477
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.476
2qbuSAHPrecorrin-2 methyltransferase/0.476
3tozNADShikimate dehydrogenase (NADP(+))/0.476
4ambDUDPutative glycosyl transferase/0.476
1gj5130Prothrombin3.4.21.50.475
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.475
3ensENSCoagulation factor X3.4.21.60.475
3px3T3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.475
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.475
1nvtNAPShikimate dehydrogenase (NADP(+))/0.474
2g004QCCoagulation factor X3.4.21.60.474
2gh5FADGlutathione reductase, mitochondrial1.8.1.70.474
2v16C47Renin3.4.23.150.474
4de10J6Beta-lactamase/0.474
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.474
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.474
1f92UKPUrokinase-type plasminogen activator3.4.21.730.473
1h74ADPHomoserine kinase2.7.1.390.473
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.473
1udaUFGUDP-glucose 4-epimerase5.1.3.20.473
3djjFADGlutathione reductase, mitochondrial1.8.1.70.473
3in6FMNUncharacterized protein/0.473
3p74FMNPentaerythritol tetranitrate reductase/0.473
3rpeFADPutative modulator of drug activity/0.473
4g95OAGDihydrofolate reductase1.5.1.30.473
1icpFMN12-oxophytodienoate reductase 11.3.1.420.472
1vi2NADQuinate/shikimate dehydrogenase/0.472
2xvhNAPPutative flavin-containing monooxygenase/0.472
3atzFMNProstaglandin F2a synthase/0.472
3fr5I4AFatty acid-binding protein, adipocyte/0.472
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.472
4k8s1QTBeta-secretase 13.4.23.460.472
4m5pFMNNADPH dehydrogenase/0.472
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.472
1bil0IURenin3.4.23.150.471
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.471
2iqgF2IBeta-secretase 13.4.23.460.471
2j2pSC2Ficolin-2/0.471
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.471
3gfbNADL-threonine 3-dehydrogenase/0.471
3tr05GPGuanylate kinase/0.471
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.471
4bti7R9Coagulation factor X3.4.21.60.471
4fuf8UPUrokinase-type plasminogen activator3.4.21.730.471
4ke11R6Beta-secretase 13.4.23.460.471
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.471
5ftfADPTPR domain protein/0.471
1ay0TPPTransketolase 12.2.1.10.470
1icqFMN12-oxophytodienoate reductase 11.3.1.420.470
1lc3NADBiliverdin reductase A1.3.1.240.470
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.470
1vyrFMNPentaerythritol tetranitrate reductase/0.470
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.470
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.470
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.470
4dptAGSMevalonate diphosphate decarboxylase/0.470
4fsl0VBBeta-secretase 13.4.23.460.470
4j75TYMTryptophan--tRNA ligase/0.470
4rnuFMNNADPH dehydrogenase 11.6.99.10.470
5cyoGDPSeptin-9/0.470
1kqnNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.469
1x1aSAMC-20 methyltransferase/0.469
2a5kAZPReplicase polyprotein 1ab3.4.220.469
2dhfDZFDihydrofolate reductase1.5.1.30.469
2wf4ZY4Beta-secretase 13.4.23.460.469
3atyFMNProstaglandin F2a synthase/0.469
3veu0GOBeta-secretase 13.4.23.460.469
3vydVYDRenin3.4.23.150.469
4bvbAR6NAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.469
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.469
4f5yC2EStimulator of interferon genes protein/0.469
4oqyNDP(S)-imine reductase/0.469
5fwnNAPPutative dehydrogenase/0.469
1dyhDZFDihydrofolate reductase1.5.1.30.468
1f20FADNitric oxide synthase, brain1.14.13.390.468
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.468
2dsgSAHDiphthine synthase/0.468
3p82FMNPentaerythritol tetranitrate reductase/0.468
4gid0GHBeta-secretase 13.4.23.460.468
4i101BSBeta-secretase 13.4.23.460.468
4opiFDAConserved Archaeal protein/0.468
1bwsNDPGDP-L-fucose synthase/0.467
1ds7FMNOxygen-insensitive NAD(P)H nitroreductase/0.467
1v453DGPurine nucleoside phosphorylase2.4.2.10.467
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.467
2p8hMY9Beta-secretase 13.4.23.460.467
2rcyNAPPyrroline-5-carboxylate reductase/0.467
2vijC44Beta-secretase 13.4.23.460.467
3f63GTXGlutathione transferase GST1-4/0.467
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.467
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.467
3nsh957Beta-secretase 13.4.23.460.467
3o0o5ADVitamin B12-dependent ribonucleotide reductase/0.467
3s1dZIRCytokinin dehydrogenase 11.5.99.120.467
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.467
4ewo996Beta-secretase 13.4.23.460.467
4g7gVFVLanosterol 14-alpha-demethylase/0.467
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.467
4i0i957Beta-secretase 13.4.23.460.467
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.466
1nj6A5AProline--tRNA ligase/0.466
1o2g696Prothrombin3.4.21.50.466
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.466
2zsaADPPantothenate kinase2.7.1.330.466
3d2pCOAAmino-acid acetyltransferase/0.466
3d3wNAPL-xylulose reductase1.1.1.100.466
3imgBZ3Pantothenate synthetase6.3.2.10.466
3nutSAHPrecorrin-3 methylase/0.466
3vswR31Renin3.4.23.150.466
4acxS8ZBeta-secretase 13.4.23.460.466
4blrUTPNTPase P4/0.466
1bwlFMNNADPH dehydrogenase 11.6.99.10.465
1ia1NDPDihydrofolate reductase1.5.1.30.465
1n2jPAFPantothenate synthetase6.3.2.10.465
1x1bSAHC-20 methyltransferase/0.465
2g1n1IGRenin3.4.23.150.465
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.465
2zhe13UProthrombin3.4.21.50.465
3c1kT15Prothrombin3.4.21.50.465
3ixj586Beta-secretase 13.4.23.460.465
3nl6TPSUncharacterized protein/0.465
4c13UMLUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase/0.465
4e2bFMNDehydrogenase/0.465
4eb5PLPCysteine desulfurase IscS 2/0.465
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.464
1icsFMN12-oxophytodienoate reductase 11.3.1.420.464
1pjcNADAlanine dehydrogenase/0.464
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.464
2gz7D3FOrf1a polyprotein/0.464
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.464
3opxU5PSuppressor of disruption of TFIIS/0.464
3tneRITCandidapepsin-13.4.23.240.464
4dfrMTXDihydrofolate reductase1.5.1.30.464
4f9gC2EStimulator of interferon genes protein/0.464
4lxk1YTBeta-secretase 13.4.23.460.464
4q0kGA3Phytohormone-binding protein/0.464
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.463
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.463
2iko7IGRenin3.4.23.150.463
2ph6712Beta-secretase 13.4.23.460.463
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.463
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.463
3v2uATPProtein GAL3/0.463
4bttVYRCoagulation factor X3.4.21.60.463
4nbwNADShort-chain dehydrogenase/reductase SDR/0.463
4yaiNAIC alpha-dehydrogenase/0.463
1aj22PHDihydropteroate synthase/0.462
1lbcCYZGlutamate receptor 2/0.462
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.462
2ifaFMNUncharacterized protein/0.462
2zvbSAHPrecorrin-3 C17-methyltransferase/0.462
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.462
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.462
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.462
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.462
4yj2GTPTubulin alpha-1B chain/0.462
1bim0QBRenin3.4.23.150.461
1ddsMTXDihydrofolate reductase1.5.1.30.461
1h65GDPTranslocase of chloroplast 343.6.50.461
1sdmADPKinesin heavy chain-like protein/0.461
2abjPLPBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.461
2b3dFADModulator of drug activity B/0.461
2ghlLIBMitogen-activated protein kinase 14/0.461
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.461
2ntrL00Beta-secretase 13.4.23.460.461
2viyVG3Beta-secretase 13.4.23.460.461
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.461
3g0bT22Dipeptidyl peptidase 4/0.461
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.461
3lsmSFDPyranose 2-oxidase/0.461
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.461
3r9uFADThioredoxin reductase/0.461
3rfxNADUronate dehydrogenase/0.461
3zkyWT4Isopenicillin N synthase1.21.3.10.461
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.461
4driRAPSerine/threonine-protein kinase mTOR2.7.11.10.461
4driRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.461
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.461
4k6fNAPPutative Acetoacetyl-CoA reductase/0.461
4qaiFMNNADPH dehydrogenase/0.461
5a1tNAIL-lactate dehydrogenase/0.461
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.460
1omoNADAlanine dehydrogenase/0.460
1qrrUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.460
1udbUFGUDP-glucose 4-epimerase5.1.3.20.460
2a9y26AAdenosine kinase2.7.1.200.460
2drcMTXDihydrofolate reductase1.5.1.30.460
2iiqC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.460
2il2LIXRenin3.4.23.150.460
2z3nPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.460
2znq401Peroxisome proliferator-activated receptor delta/0.460
3axkNDPRibulose bisphosphate carboxylase large chain4.1.1.390.460
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.460
3hk1B64Fatty acid-binding protein, adipocyte/0.460
3n0hTOPDihydrofolate reductase1.5.1.30.460
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.460
4yagNAIC alpha-dehydrogenase/0.460
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.460
1cl0FADThioredoxin reductase1.8.1.90.459
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.459
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.459
2a1oCAMCamphor 5-monooxygenase1.14.15.10.459
2c20NADUDP-glucose 4-epimerase/0.459
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.459
2nniMTKCytochrome P450 2C8/0.459
2wp9CBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.459
2wp9CBESuccinate dehydrogenase cytochrome b556 subunit/0.459
2xpuTDCTetracycline repressor protein class D/0.459
3ivgFG5Pantothenate synthetase6.3.2.10.459
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.459
3p8iFMNPentaerythritol tetranitrate reductase/0.459
3zcnATPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.459
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.459
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.459
4qecNAPElxO/0.459
1jolFFODihydrofolate reductase1.5.1.30.458
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.458
1zgi382Prothrombin3.4.21.50.458
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.458
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.458
2whqHI6Acetylcholinesterase3.1.1.70.458
3a0tADPSensor histidine kinase/0.458
3ieuGDPGTPase Era/0.458
3imgBZ2Pantothenate synthetase6.3.2.10.458
3otwCOAPhosphopantetheine adenylyltransferase/0.458
3ut5LOCTubulin beta chain/0.458
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.458
4r81FMNPredicted NADH dehydrogenase/0.458
4xboSAHtRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ2.1.1.2000.458
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.457
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1mbbEEBUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.457
1mvsDTMDihydrofolate reductase1.5.1.30.457
2dxiATPGlutamate--tRNA ligase6.1.1.170.457
2ejzSAHDiphthine synthase/0.457
2zff53UProthrombin3.4.21.50.457
3ai3NDPNADPH-sorbose reductase/0.457
3hlwCE3Beta-lactamase/0.457
3ivxFG6Pantothenate synthetase6.3.2.10.457
3zhbNAPPutative dehydrogenase/0.457
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.457
4hmxFMNPyridoxamine 5'-phosphate oxidase/0.457
4lcjNADC-terminal-binding protein 2/0.457
5ao1DG3Deoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.457
1dr3HBIDihydrofolate reductase1.5.1.30.456
1i5eU5PUracil phosphoribosyltransferase/0.456
1ja0NAPNADPH--cytochrome P450 reductase/0.456
1kp3ATPArgininosuccinate synthase6.3.4.50.456
1sqtUI3Urokinase-type plasminogen activator3.4.21.730.456
1tj0FADBifunctional protein PutA1.5.5.20.456
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.456
2daaDCSD-alanine aminotransferase2.6.1.210.456
2e07SAHDiphthine synthase/0.456
2futH1SHeparin and heparin-sulfate lyase/0.456
3coy53HPantothenate synthetase6.3.2.10.456
3ioeA7DPantothenate synthetase6.3.2.10.456
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.456
3mk6ACOPantothenate kinase 32.7.1.330.456
3oafOAGDihydrofolate reductase1.5.1.30.456
3r96ACOMccE protein/0.456
4ccqFADThioredoxin reductase/0.456
4dpuAGSMevalonate diphosphate decarboxylase/0.456
4e31JHZMethyltransferase/0.456
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.456
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.456
5c41ACPRibokinase/0.456
1bp6UMPThymidylate synthase/0.455
1ddrMTXDihydrofolate reductase1.5.1.30.455
1dj2GDPAdenylosuccinate synthetase, chloroplastic/0.455
1drhNAPDihydrofolate reductase1.5.1.30.455
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.455
1k7l544Peroxisome proliferator-activated receptor alpha/0.455
1ra3NAPDihydrofolate reductase1.5.1.30.455
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.455
2cjiGSKCoagulation factor X3.4.21.60.455
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.455
2pncCLUPrimary amine oxidase, liver isozyme/0.455
2zbaZBATrichothecene 3-O-acetyltransferase/0.455
3lsiFADPyranose 2-oxidase/0.455
3ziuLSSLeucyl-tRNA synthetase/0.455
4btu6XSCoagulation factor X3.4.21.60.455
4e2yJHZMethyltransferase/0.455
4gddNAIUDP-galactopyranose mutase/0.455
5czySAMEukaryotic huntingtin interacting protein B/0.455
1j9zFADNADPH--cytochrome P450 reductase/0.454
1kh3ANPArgininosuccinate synthase/0.454
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.454
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.454
2ab8MTPAdenosine kinase2.7.1.200.454
2g247IGRenin3.4.23.150.454
2iibC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.454
2p6dSAHDiphthine synthase/0.454
2qzlIXSBeta-secretase 13.4.23.460.454
2xhd7T9Glutamate receptor 2/0.454
3akzGSUGlutamate--tRNA ligase 2/0.454
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.454
3duyAFJBeta-secretase 13.4.23.460.454
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.454
3k5c0BIBeta-secretase 13.4.23.460.454
3ov7ATPCCA-adding enzyme2.7.7.720.454
3q43D66M1 family aminopeptidase3.4.110.454
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.454
4jayNAPUDP-N-acetylenolpyruvoylglucosamine reductase/0.454
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.454
5a3cNADSIR2 family protein/0.454
1c4uIH1Prothrombin3.4.21.50.453
1d0lBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.453
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.453
1jil485Tyrosine--tRNA ligase/0.453
1pqc444Oxysterols receptor LXR-beta/0.453
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.453
1rneC60Renin3.4.23.150.453
1u71MXADihydrofolate reductase1.5.1.30.453
1wngSAHDiphthine synthase/0.453
1yb5NAPQuinone oxidoreductase1.6.5.50.453
2e0nSAHPrecorrin-2 C20-methyltransferase/0.453
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.453
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.453
3gvhNADMalate dehydrogenase/0.453
3ibqATPPyridoxal kinase/0.453
3ig6438Urokinase-type plasminogen activator3.4.21.730.453
3ivmZPRProlyl endopeptidase/0.453
3ohh3HHBeta-secretase 13.4.23.460.453
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.453
3p8jFMNPentaerythritol tetranitrate reductase/0.453
4dd8BATDisintegrin and metalloproteinase domain-containing protein 83.4.240.453
4eb7PLPCysteine desulfurase IscS 2/0.453
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.453
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.453
4wzhFMNDihydroorotate dehydrogenase (fumarate)/0.453
1g63FMNEpidermin decarboxylase4.1.10.452
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1mvtDTMDihydrofolate reductase1.5.1.30.452
1o6zNADMalate dehydrogenase/0.452
1pd9CO4Dihydrofolate reductase1.5.1.30.452
1s3uTQDDihydrofolate reductase1.5.1.30.452
1vjiFMN12-oxophytodienoate reductase 11.3.1.420.452
2bjfDXCCholoylglycine hydrolase3.5.1.240.452
2g0bNLTLong-chain N-acyl amino acid synthase/0.452
2g1s4IGRenin3.4.23.150.452
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.452
2xfsJ01Uncharacterized protein/0.452
3ai2NDPNADPH-sorbose reductase/0.452
3i25MV7Beta-secretase 13.4.23.460.452
3kkzSAMUncharacterized protein/0.452
3tnlNADShikimate dehydrogenase (NADP(+))/0.452
3zpoK0IHistone demethylase UTY1.14.110.452
4du82P0Mevalonate diphosphate decarboxylase/0.452
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.452
4irnFADAnaB/0.452
4j4nD44Peptidylprolyl isomerase/0.452
4loi1YCStimulator of interferon genes protein/0.452
4rnwFMNNADPH dehydrogenase 11.6.99.10.452
4wecNADShort chain dehydrogenase/0.452
4ycpFMNtRNA-dihydrouridine(16) synthase/0.452
4xnw2IDP2Y purinoceptor 1/0.452
3vw7VPXProteinase-activated receptor 1/0.452
1dr3TAPDihydrofolate reductase1.5.1.30.451
1dyiFOLDihydrofolate reductase1.5.1.30.451
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.451
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.451
1tehNADAlcohol dehydrogenase class-31.1.1.10.451
1towCRZFatty acid-binding protein, adipocyte/0.451
2he5NDPAldo-keto reductase family 1 member C211.1.10.451
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.451
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.451
2pckSAHDiphthine synthase/0.451
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.451
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.451
2y5hY5HCoagulation factor X3.4.21.60.451
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.451
3fr4F8AFatty acid-binding protein, adipocyte/0.451
3h3t16HCollagen type IV alpha-3-binding protein/0.451
3hyoADPPyridoxal kinase/0.451
3lpiZ74Beta-secretase 13.4.23.460.451
3muoZPRProlyl endopeptidase/0.451
3s2v3HUGlutamate receptor ionotropic, kainate 1/0.451
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.451
4bb3KKAIsopenicillin N synthase1.21.3.10.451
4dpi0N1Beta-secretase 13.4.23.460.451
4ha9NDP2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase1.1.1.3020.451
4q71FADBifunctional protein PutA/0.451
5dw50T1Succinyl-CoA:acetate CoA-transferase/0.451
1draMTXDihydrofolate reductase1.5.1.30.450
1p0pBCHCholinesterase3.1.1.80.450
1tkaN3TTransketolase 12.2.1.10.450
1v5z2HCMajor NAD(P)H-flavin oxidoreductase1.6.990.450
2hm1LIQBeta-secretase 13.4.23.460.450
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.450
2oegUPGUDP-glucose pyrophosphorylase/0.450
2zcvNDPQuinone oxidoreductase 21.6.5.20.450
2znk31UProthrombin3.4.21.50.450
3hatGLY_VAL_ARG_RNGProthrombin3.4.21.50.450
3ingNDPHomoserine dehydrogenase related protein/0.450
3kjm245Cytokinin dehydrogenase 11.5.99.120.450
3kxw1ZZSaframycin Mx1 synthetase B/0.450
3rfaSAMDual-specificity RNA methyltransferase RlmN/0.450
3t64DU3Deoxyuridine 5'-triphosphate nucleotidohydrolase/0.450
3toxNAPPutative oxidoreductase/0.450
4e32DWNMethyltransferase/0.450
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.450
4i1iNADMalate dehydrogenase/0.450
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.450
4pleCPSNuclear receptor subfamily 5 group A member 2/0.450
4rp8ASCAscorbate-specific PTS system EIIC component/0.450
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1dyjDDFDihydrofolate reductase1.5.1.30.449
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1ri3SAHmRNA cap guanine-N7 methyltransferase2.1.1.560.449
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.449
2ekaSAHDiphthine synthase/0.449
2emuSAHDiphthine synthase/0.449
2g1y5IGRenin3.4.23.150.449
2wzySQXSoluble acetylcholine receptor/0.449
2x8hFADThioredoxin glutathione reductase/0.449
2xfiXFIBeta-secretase 13.4.23.460.449
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.449
3hl0NADMaleylacetate reductase/0.449
3n4kSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.449
4azy7F3Beta-secretase 13.4.23.460.449
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.449
4d89BXDBeta-secretase 13.4.23.460.449
4ddhMS0Pantothenate synthetase6.3.2.10.449
4hmsFMNPhenazine biosynthesis protein PhzG1.40.449
4ipw1G7Mycocyclosin synthase1.14.21.90.449
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.449
5b0oADPFlagellum-specific ATP synthase3.6.3.140.449
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.448
1nm6L86Prothrombin3.4.21.50.448
1q84TZ4Acetylcholinesterase3.1.1.70.448
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.448
1ri4SAMmRNA cap guanine-N7 methyltransferase2.1.1.560.448
1t2cNAIL-lactate dehydrogenase1.1.1.270.448
1t4u81AProthrombin3.4.21.50.448
2e15SAHDiphthine synthase/0.448
2emrSAHDiphthine synthase/0.448
2gnaGDUUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.448
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.448
2hizLIJBeta-secretase 13.4.23.460.448
2hp2KE4Glutamate-1-semialdehyde 2,1-aminomutase5.4.3.80.448
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.448
2owkSAHDiphthine synthase/0.448
2qo9ANPEphrin type-A receptor 32.7.10.10.448
2wsiFADFAD synthase2.7.7.20.448
2y60M8FIsopenicillin N synthase1.21.3.10.448
3cluFADElectron transfer flavoprotein subunit alpha/0.448
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.448
3m30COMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.448
3m30COMMethyl-coenzyme M reductase I subunit beta2.8.4.10.448
3o7bSAHRibosomal RNA small subunit methyltransferase Nep1/0.448
3uylTYDProbable NDP-rhamnosyltransferase/0.448
3wagTYDGlycosyltransferase/0.448
4b79NADProbable short-chain dehydrogenase/0.448
4gk3L87Ephrin type-A receptor 32.7.10.10.448
4m6jNDPDihydrofolate reductase1.5.1.30.448
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.448
1bk0ACVIsopenicillin N synthase1.21.3.10.447
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.447
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.447
1nzdUPGDNA beta-glucosyltransferase/0.447
1xs7MMIBeta-secretase 13.4.23.460.447
2aa3AP0L-lactate dehydrogenase/0.447
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.447
2cftPLPPyridoxal phosphate phosphatase/0.447
2dv4SAHDiphthine synthase/0.447
2ikuLIYRenin3.4.23.150.447
2irzI02Beta-secretase 13.4.23.460.447
2iviACWIsopenicillin N synthase1.21.3.10.447
2yy8SAMtRNA (cytidine(56)-2'-O)-methyltransferase/0.447
3kgcLY7Glutamate receptor 2/0.447
3l5lFMNXenobiotic reductase/0.447
3oixFMNDihydroorotate dehydrogenase/0.447
3zoiM2WIsopenicillin N synthase1.21.3.10.447
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.447
4fm80UQBeta-secretase 13.4.23.460.447
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.447
4iv6FDAIsovaleryl-CoA dehydrogenase/0.447
4u0mATPCyclic GMP-AMP synthase/0.447
4wxxSAHDNA (cytosine-5)-methyltransferase 12.1.1.370.447
4yqfGDPSeptin-9/0.447
1b5tFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.446
1dhjMTXDihydrofolate reductase1.5.1.30.446
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.446
1kkq471Peroxisome proliferator-activated receptor alpha/0.446
1ri1GTGmRNA cap guanine-N7 methyltransferase2.1.1.560.446
1rx8NAPDihydrofolate reductase1.5.1.30.446
1touB1VFatty acid-binding protein, adipocyte/0.446
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.446
1vhzAPRADP compounds hydrolase NudE3.6.10.446
1yhnGTPRas-related protein Rab-7a/0.446
2dc1NADProbable L-aspartate dehydrogenase/0.446
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.446
2gjlFMNNitronate monooxygenase1.13.12.160.446
2w6zL21Biotin carboxylase6.3.4.140.446
2zvcSAHPrecorrin-3 C17-methyltransferase/0.446
3bk2U5PRibonuclease J/0.446
3ijoB4DGlutamate receptor 2/0.446
3lqfNADGalactitol dehydrogenase/0.446
3lu1UD2UDP-N-acetylglucosamine 4-epimerase/0.446
3t2vKKJPeptidoglycan recognition protein 1/0.446
4acuQN7Beta-secretase 13.4.23.460.446
4relKMPGlycosyltransferase/0.446
5bsgNAPPyrroline-5-carboxylate reductase/0.446
1culFOKAdenylate cyclase type 2/0.445
1culFOKAdenylate cyclase type 5/0.445
1hb1OCVIsopenicillin N synthase1.21.3.10.445
1i6xCMPcAMP-activated global transcriptional regulator CRP/0.445
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.445
1ozpACOMycothiol acetyltransferase2.3.1.1890.445
1re7FOLDihydrofolate reductase1.5.1.30.445
2a7r5GPGMP reductase 2/0.445
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2g1o2IGRenin3.4.23.150.445
2hr8SAHDiphthine synthase/0.445
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.445
2rirNAPDipicolinate synthase subunit A/0.445
2vhtATPNTPase P4/0.445
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.445
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.445
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.445
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.445
3k4cFADPyranose 2-oxidase/0.445
3khuUPGUDP-glucose 6-dehydrogenase1.1.1.220.445
3pm1ETHTH-type transcriptional regulator QacR/0.445
3zhyFM61-deoxy-D-xylulose 5-phosphate reductoisomerase/0.445
4lol1YEStimulator of interferon genes protein/0.445
4m4922YL-lactate dehydrogenase A chain1.1.1.270.445
4rvdSAMD-mycarose 3-C-methyltransferase/0.445
4ure1PSCyclohexanol dehydrogenase/0.445
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.445
1bdmNAXMalate dehydrogenase/0.444
1dhfFOLDihydrofolate reductase1.5.1.30.444
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.444
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.444
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.444
1kbiFMNCytochrome b2, mitochondrial1.1.2.30.444
1kvuUPGUDP-glucose 4-epimerase5.1.3.20.444
1udcUFMUDP-glucose 4-epimerase5.1.3.20.444
2bn4FMNNADPH--cytochrome P450 reductase/0.444
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.444
2e17SAHDiphthine synthase/0.444
2fznFADBifunctional protein PutA1.5.5.20.444
2xx91NFGlutamate receptor 2/0.444
3jv7NADSecondary alcohol dehydrogenase/0.444
3lcjCOAPhosphopantetheine adenylyltransferase/0.444
3lpjZ75Beta-secretase 13.4.23.460.444
3oetNADErythronate-4-phosphate dehydrogenase/0.444
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.444
3udk095Beta-secretase 13.4.23.460.444
4b4vL34Bifunctional protein FolD/0.444
4b7754MBeta-secretase 13.4.23.460.444
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.444
4dbzNDPPutative ketoacyl reductase1.3.10.444
4dpy2P0Mevalonate diphosphate decarboxylase/0.444
4eu4COASuccinyl-CoA:acetate CoA-transferase/0.444
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.444
4tmbFMNOld yellow enzyme/0.444
4x9mFADUncharacterized protein MG039 homolog/0.444
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.444
4yxm2BADNA integrity scanning protein DisA/0.444
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.444
5l3dFADLysine-specific histone demethylase 1A10.444
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.443
1sb1165Prothrombin3.4.21.50.443
1ty9FMNPhenazine biosynthesis protein PhzG1.40.443
1uxkNADMalate dehydrogenase/0.443
2djxFMNDihydroorotate dehydrogenase (fumarate)1.3.98.10.443
2ed3SAHDiphthine synthase/0.443
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.443
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.443
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.443
2vbdV10Isopenicillin N synthase1.21.3.10.443
2vkmBSDBeta-secretase 13.4.23.460.443
2wu4HBPAcetylcholinesterase3.1.1.70.443
2x3fAPCPantothenate synthetase/0.443
3a9wNADNDP-sugar epimerase/0.443
3b2eADPATPase GET3/0.443
3d91REMRenin3.4.23.150.443
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.443
3fp0FP015-O-acetyltransferase/0.443
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.443
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.443
3q70RITCandidapepsin-23.4.23.240.443
3wqmB29Diterpene synthase3.1.7.80.443
4b70WM9Beta-secretase 13.4.23.460.443
4bfxZVXPantothenate kinase2.7.1.330.443
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.443
4er6AW2Histone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.443
4g3jVNTLanosterol 14-alpha-demethylase/0.443
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.443
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.443
1dr2TAPDihydrofolate reductase1.5.1.30.442
1f8fNADBenzyl alcohol dehydrogenase/0.442
1gw2FERPeroxidase C1A1.11.1.70.442
1h62ANBPentaerythritol tetranitrate reductase/0.442
1honGNHAdenylosuccinate synthetase/0.442
1kp2ATPArgininosuccinate synthase6.3.4.50.442
1l5s700Glycogen phosphorylase, liver form2.4.1.10.442
1nzfUPGDNA beta-glucosyltransferase/0.442
1w51L01Beta-secretase 13.4.23.460.442
1x1dSAHC-20 methyltransferase/0.442
1zji2PG2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.442
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.442
2d8aNADL-threonine 3-dehydrogenase/0.442
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.442
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.442
2ehlSAHDiphthine synthase/0.442
2eleSAHDiphthine synthase/0.442
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.442
2p83MR0Beta-secretase 13.4.23.460.442
2q14ADPPhosphohydrolase/0.442
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.442
2wzwNDPNitroreductase NfnB/0.442
2x0rNADMalate dehydrogenase/0.442
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.442
2xlrFADPutative flavin-containing monooxygenase/0.442
2zfq45UProthrombin3.4.21.50.442
3ag6PAJPantothenate synthetase/0.442
3beoUD1UDP-N-acetylglucosamine 2-epimerase/0.442
3dm5GDPSignal recognition particle 54 kDa protein/0.442
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.442
3fktSIIBeta-secretase 13.4.23.460.442
3ixk929Beta-secretase 13.4.23.460.442
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.442
3pftFMNFlavin reductase/0.442
3phiNDPShikimate dehydrogenase (NADP(+))/0.442
3pndFADFAD:protein FMN transferase/0.442
4a30MYAGlycylpeptide N-tetradecanoyltransferase/0.442
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.442
4ef4C2EStimulator of interferon genes protein/0.442
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.442
4gdcNDPUDP-galactopyranose mutase/0.442
4jpe1M7Beta-secretase 13.4.23.460.442
4nesUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.442
4rnvFMNNADPH dehydrogenase 11.6.99.10.442
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.442
4u3jGTPTubulin beta chain/0.442
1beuIPLTryptophan synthase alpha chain/0.441
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.441
1ex75GPGuanylate kinase2.7.4.80.441
1gj4132Prothrombin3.4.21.50.441
1mq6XLDCoagulation factor X3.4.21.60.441
1n2hPAJPantothenate synthetase6.3.2.10.441
1nj5P5AProline--tRNA ligase/0.441
1nlyAGSCag alpha/0.441
1pr9NAPL-xylulose reductase1.1.1.100.441
1pvgANPDNA topoisomerase 25.99.1.30.441
1qyvNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1tllFMNNitric oxide synthase, brain1.14.13.390.441
2dekSAHDiphthine synthase/0.441
2eh5SAHDiphthine synthase/0.441
2hk9NAPShikimate dehydrogenase (NADP(+))/0.441
2hrbNAPCarbonyl reductase [NADPH] 31.1.1.1840.441
2zgx29UProthrombin3.4.21.50.441
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.441
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.441
3k5gBJCBeta-secretase 13.4.23.460.441
3kruFMNNADH:flavin oxidoreductase/NADH oxidase/0.441
3p80P80Pentaerythritol tetranitrate reductase/0.441
3qfbFADThioredoxin reductase 1, cytoplasmic1.8.1.90.441
3qgi33FGenome polyprotein2.7.7.480.441
3qlsNDPDihydrofolate reductase1.5.1.30.441
3widNAPGlucose 1-dehydrogenase/0.441
3wswNADL-lactate dehydrogenase/0.441
4c49HCYCorticosteroid-binding globulin/0.441
4cukNAID-lactate dehydrogenase/0.441
4emtC2EStimulator of interferon genes protein/0.441
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.441
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.441
4jtqNAPAldo-keto reductase family 1 member C2/0.441
4yvz3ATDNA integrity scanning protein DisA/0.441
5hg0SAMPantothenate synthetase/0.441
8dfrNDPDihydrofolate reductase1.5.1.30.441
1a9sNOSPurine nucleoside phosphorylase2.4.2.10.440
1daaPLPD-alanine aminotransferase2.6.1.210.440
1me6IVSPlasmepsin-23.4.23.390.440
1n7hNDPGDP-mannose 4,6 dehydratase 24.2.1.470.440
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.440
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.440
1nhhANPDNA mismatch repair protein MutL/0.440
1ra8FOLDihydrofolate reductase1.5.1.30.440
1rb3MTXDihydrofolate reductase1.5.1.30.440
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.440
1u1gBBBUridine phosphorylase2.4.2.30.440
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.440
2a92NAIL-lactate dehydrogenase/0.440
2abaSTRPentaerythritol tetranitrate reductase/0.440
2b4rAESGlyceraldehyde-3-phosphate dehydrogenase/0.440
2bkjFMNNADPH-flavin oxidoreductase/0.440
2dgnDOIAdenylosuccinate synthetase isozyme 1/0.440
2dxwSAHDiphthine synthase/0.440
2g8yNADHydroxycarboxylate dehydrogenase B/0.440
2ha8SAHProbable methyltransferase TARBP1/0.440
2yd0BESEndoplasmic reticulum aminopeptidase 13.4.110.440
2znnS44Peroxisome proliferator-activated receptor alpha/0.440
3enkUPGUDP-glucose 4-epimerase/0.440
3junAJDPhenazine biosynthesis protein A/B/0.440
3mtwM3RXaa-Pro dipeptidase, putative/0.440
3sxjSAMPutative methyltransferase/0.440
3t7sSAMUncharacterized protein/0.440
4dpf0LGBeta-secretase 13.4.23.460.440
4h9tHL4Phosphotriesterase/0.440
4wriOKAOkadaic acid binding protein 2-alpha/0.440
4djhJDCKappa-type opioid receptor/0.440