sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Glutamate receptor 2
ID:	GRIA2_RAT
AC:	P19491
Organism:	Rattus norvegicus
Reign:	Eukaryota
TaxID:	10116
EC Number:	/

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Chains:

Chain Name:	Percentage of Residues within binding site
B	36 %
E	64 %

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Ligand binding site composition:

B-Factor:	28.013
Number of residues:	35
Including
Standard Amino Acids:	33
Non Standard Amino Acids:	1
Water Molecules:	1
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
1.368	1147.500

% Hydrophobic	% Polar
45.88	54.12
According to VolSite

HET Code:	B4D
Formula:	C11H14ClN3O4S3
Molecular weight:	383.895 g/mol
DrugBank ID:	-
Buried Surface Area:	63.17 %
Polar Surface area:	160.41 Å2

Number of
H-Bond Acceptors:	6
H-Bond Donors:	3
Rings:	2
Aromatic rings:	1
Anionic atoms:	0
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	5

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Mass center Coordinates

X	Y	Z
-5.07364	52.1325	-20.9215

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