sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3bhm | AHE | Carbonyl reductase [NADPH] 1 | 1.1.1.184 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3bhm | AHE | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 1.000 | |
| 3bhm | AB3 | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.930 | |
| 1wma | AB3 | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.573 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.508 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.507 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.500 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.499 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.499 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.498 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.498 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.496 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.495 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.494 | |
| 4h6p | FMN | Chromate reductase | / | 0.494 | |
| 1osv | CHC | Bile acid receptor | / | 0.493 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.492 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.491 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.490 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.490 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.489 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.489 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.488 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.487 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.486 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.485 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.484 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.483 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.482 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.482 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 1g28 | FMN | PHY3 | / | 0.481 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.481 | |
| 1tg2 | H2B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.480 | |
| 4ear | IM5 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.480 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.480 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 1ri4 | SAM | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.478 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.478 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.478 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.477 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.477 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.477 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.476 | |
| 1pua | COA | HAT A1 | / | 0.476 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.476 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.476 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.475 | |
| 2wgg | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.475 | |
| 3ksl | SZH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.475 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 4li8 | 1XQ | Tankyrase-1 | 2.4.2.30 | 0.475 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.474 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.474 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.474 | |
| 3b9l | AZZ | Serum albumin | / | 0.474 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.474 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.473 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.473 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.473 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.473 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.472 | |
| 1vgr | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.472 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.472 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.472 | |
| 3dlp | 174 | 4-chlorobenzoyl CoA ligase | / | 0.472 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.472 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.471 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.471 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.471 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.471 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.470 | |
| 1b8n | IMG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 1b8o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.470 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.470 | |
| 2hux | SAH | Diphthine synthase | / | 0.470 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.470 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.470 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
| 4y1b | NAP | AntE | / | 0.470 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.469 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.469 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.469 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.469 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.469 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.468 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.468 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.468 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.468 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.468 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.468 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.467 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.467 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.467 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.467 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.466 | |
| 3n4l | 842 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 3pd5 | TSB | Threonine--tRNA ligase | 6.1.1.3 | 0.466 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.466 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.466 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.465 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 4rrk | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.465 | |
| 1a4l | DCF | Adenosine deaminase | 3.5.4.4 | 0.464 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.464 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.464 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.464 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.464 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.464 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.463 | |
| 2vcx | D26 | Hematopoietic prostaglandin D synthase | / | 0.463 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.463 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.463 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.462 | |
| 1ppj | ANY | Cytochrome b | / | 0.462 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.462 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.462 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.462 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.462 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.462 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.462 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.462 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 2pch | SAH | Diphthine synthase | / | 0.461 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.461 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.461 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.461 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.460 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.460 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.460 | |
| 1upb | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.460 | |
| 1xqp | 8HG | N-glycosylase/DNA lyase | / | 0.460 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.460 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.460 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.460 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.460 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4l4x | NDP | AmphI | / | 0.460 | |
| 1lwx | AZD | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.459 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.459 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.459 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.459 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4j0y | 1H6 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 4l33 | F70 | Tankyrase-2 | 2.4.2.30 | 0.459 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.459 | |
| 4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.459 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.459 | |
| 5kp2 | COA | 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 | / | 0.459 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.458 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.458 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.458 | |
| 2o8b | ADP | DNA mismatch repair protein Msh2 | / | 0.458 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.458 | |
| 3i6r | J5Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.458 | |
| 4bub | ADP | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase | / | 0.458 | |
| 4f1y | CNI | Glutamate receptor 3 | / | 0.458 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.458 | |
| 4lb2 | DM5 | Serum albumin | / | 0.458 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.457 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.457 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.457 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 2qds | MCO | Metallo-beta-lactamase type 2 | / | 0.457 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.457 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.457 | |
| 1j3j | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.456 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.456 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.456 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.456 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.456 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.456 | |
| 3tc5 | 3T5 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 5.2.1.8 | 0.456 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.456 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.456 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.456 | |
| 4qbi | AP5 | Adenylate kinase | / | 0.456 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.456 | |
| 1g8o | U5P | N-acetyllactosaminide alpha-1,3-galactosyltransferase | / | 0.455 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.455 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 2e95 | B75 | Geranylgeranyl pyrophosphate synthase | / | 0.455 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.455 | |
| 3cso | XNI | Genome polyprotein | 2.7.7.48 | 0.455 | |
| 3wag | TYD | Glycosyltransferase | / | 0.455 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.455 | |
| 4lwp | SAH | Arginine N-methyltransferase, putative | / | 0.455 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.455 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.455 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.454 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.454 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.454 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.454 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.454 | |
| 2buf | ADP | Acetylglutamate kinase | / | 0.454 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3g1o | RF1 | HTH-type transcriptional regulator EthR | / | 0.454 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.454 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.454 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.454 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 4v2g | CTC | Tetracycline repressor protein class D | / | 0.454 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.453 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.453 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2v7q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.453 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.453 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.453 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.453 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.453 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.453 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.453 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.453 | |
| 3up5 | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.453 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.453 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.453 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.453 | |
| 4i0f | 1BF | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.453 | |
| 4jhi | EMU | Nodulin-13 | / | 0.453 | |
| 4nbb | 9CA | Terminal oxygenase component of carbazole | / | 0.453 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.453 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.453 | |
| 5hgc | HCY | Uncharacterized protein | / | 0.453 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.453 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 2a5c | 8DA | Avidin | / | 0.452 | |
| 2bxm | IMN | Serum albumin | / | 0.452 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2rtm | IMI | Streptavidin | / | 0.452 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.452 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3ndj | JHZ | Methyltransferase | / | 0.452 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.452 | |
| 3tpr | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.452 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.452 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.452 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.452 | |
| 4ih7 | 1ER | Genome polyprotein | 2.7.7.48 | 0.452 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.452 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.452 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.451 | |
| 1cm0 | COA | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.451 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.451 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1lke | DOG | Bilin-binding protein | / | 0.451 | |
| 1p4m | ADP | Riboflavin kinase | 2.7.1.26 | 0.451 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.451 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2dxw | SAH | Diphthine synthase | / | 0.451 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.451 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.451 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3dg8 | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3eks | CY9 | Actin-5C | / | 0.451 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.451 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.451 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.451 | |
| 4bfd | 8T3 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.451 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.451 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.451 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.450 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1rti | HEF | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.450 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.450 | |
| 2huq | SAH | Diphthine synthase | / | 0.450 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.450 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 2x0e | TYD | WsaF | / | 0.450 | |
| 2z6r | SAH | Diphthine synthase | / | 0.450 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.450 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.450 | |
| 3pej | BC2 | Endoplasmin homolog, putative | / | 0.450 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.450 | |
| 3w2f | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.450 | |
| 4f1q | 0RZ | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.450 | |
| 4h6u | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 4j49 | NAI | Uncharacterized protein | / | 0.450 | |
| 4jv3 | N32 | Beta-ketoacyl synthase | / | 0.450 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.450 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.449 | |
| 1qy2 | IPZ | Major urinary protein 1 | / | 0.449 | |
| 1tlc | F89 | Thymidylate synthase | / | 0.449 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.449 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.449 | |
| 2d81 | RB3 | Poly(3-hydroxybutyrate) depolymerase | / | 0.449 | |
| 2huv | SAH | Diphthine synthase | / | 0.449 | |
| 2iyp | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.449 | |
| 2pck | SAH | Diphthine synthase | / | 0.449 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.449 | |
| 3ae4 | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.449 | |
| 3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.449 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.449 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.449 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.449 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 3rbq | GLY_ALA_GLY_DAO | Protein unc-119 homolog A | / | 0.449 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.449 | |
| 4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.449 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.449 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.449 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.449 | |
| 4gtp | 7TP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.449 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.449 | |
| 4uof | DAT | Nucleoside diphosphate kinase | / | 0.449 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1rxj | BNI | Streptavidin | / | 0.448 | |
| 1ulb | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2dsg | SAH | Diphthine synthase | / | 0.448 | |
| 2vk8 | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.448 | |
| 2xvv | 9DN | Serum albumin | / | 0.448 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.448 | |
| 3dmj | GWE | Pol protein | / | 0.448 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 3gy9 | COA | GCN5-related N-acetyltransferase | / | 0.448 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
| 3v1u | HXC | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.448 | |
| 4fgj | 1PQ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.448 | |
| 4j3l | AJ5 | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.448 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.448 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.447 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.447 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.447 | |
| 2emu | SAH | Diphthine synthase | / | 0.447 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.447 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3keo | NAD | Redox-sensing transcriptional repressor Rex | / | 0.447 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.447 | |
| 4dpd | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.447 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.447 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.447 | |
| 4tla | ADP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.447 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.447 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.446 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1n0u | SO1 | Elongation factor 2 | / | 0.446 | |
| 1ych | FMN | Nitric oxide reductase | 1 | 0.446 | |
| 2bxq | IMN | Serum albumin | / | 0.446 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.446 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2izf | BTN | Streptavidin | / | 0.446 | |
| 2yhu | WHF | Pteridine reductase | / | 0.446 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.446 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.446 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.446 | |
| 3dga | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.446 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.446 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1e2n | RCA | Thymidine kinase | / | 0.445 | |
| 1f9a | ATP | Nicotinamide-nucleotide adenylyltransferase | / | 0.445 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.445 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.445 | |
| 1tdc | UMP | Thymidylate synthase | / | 0.445 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.445 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.445 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.445 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.445 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.445 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.445 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.445 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.445 | |
| 2ihv | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.445 | |
| 2iu8 | UD1 | UDP-3-O-acylglucosamine N-acyltransferase | 2.3.1 | 0.445 | |
| 2k1q | GLU_LEU_IBU_OBF_FE3 | Polyprotein | / | 0.445 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.445 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.445 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.445 | |
| 3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.445 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.445 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.445 | |
| 4boe | CLR | Japanin | / | 0.445 | |
| 4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4li7 | 1XP | Tankyrase-1 | 2.4.2.30 | 0.445 | |
| 4ple | CPS | Nuclear receptor subfamily 5 group A member 2 | / | 0.445 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.445 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.444 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.444 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.444 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.444 | |
| 1tys | TMP | Thymidylate synthase | / | 0.444 | |
| 2b8v | 3BN | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.444 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.444 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.444 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.444 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.444 | |
| 2rtq | IMI | Streptavidin | / | 0.444 | |
| 2xjc | 5GP | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.444 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2z4j | DHT | Androgen receptor | / | 0.444 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.444 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.444 | |
| 3gg2 | UGA | Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family | / | 0.444 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.444 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.444 | |
| 3mne | DEX | Glucocorticoid receptor | / | 0.444 | |
| 3nhl | YTR | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.444 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.444 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.444 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.444 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.444 | |
| 4img | NGF | N-acetylneuraminate lyase | / | 0.444 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4l7v | SAH | Protein-L-isoaspartate O-methyltransferase | / | 0.444 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 4njo | NAD | D-3-phosphoglycerate dehydrogenase, putative | / | 0.444 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.444 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.444 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.444 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 4ybr | NAP | Probable nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.444 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.443 | |
| 1dd6 | MCI | Metallo-beta-lactamase type 2 | / | 0.443 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 1nas | ASE | Sepiapterin reductase | 1.1.1.153 | 0.443 | |
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.443 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.443 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.443 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.443 | |
| 2p15 | EZT | Estrogen receptor | / | 0.443 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.443 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.443 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.443 | |
| 3g11 | P9C | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.443 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3pn4 | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.443 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.443 | |
| 4bew | ACP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.443 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.443 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.443 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.443 | |
| 1cgz | STL | Chalcone synthase 2 | 2.3.1.74 | 0.442 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.442 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.442 | |
| 1mx0 | ANP | Type 2 DNA topoisomerase 6 subunit B | / | 0.442 | |
| 1qv0 | CZH | Obelin | / | 0.442 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 1srh | MOB | Streptavidin | / | 0.442 | |
| 1til | ATP | Anti-sigma F factor | / | 0.442 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 2ako | ADP | Glutamate 5-kinase | / | 0.442 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.442 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.442 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2ow9 | SP6 | Collagenase 3 | 3.4.24 | 0.442 | |
| 2piw | DHT | Androgen receptor | / | 0.442 | |
| 2rgx | AP5 | Adenylate kinase | / | 0.442 | |
| 2rti | GLL | Streptavidin | / | 0.442 | |
| 2tsr | UMP | Thymidylate synthase | 2.1.1.45 | 0.442 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.442 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.442 | |
| 3c11 | GDM | ATP-dependent molecular chaperone HSP82 | / | 0.442 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.442 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.442 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3n0y | APC | Adenylate cyclase 2 | / | 0.442 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.442 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.442 | |
| 3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.442 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.442 | |
| 4eb3 | 0O3 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.442 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.442 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4odo | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.442 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.442 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
| 5cuq | NSC | Genome polyprotein | / | 0.442 | |
| 1clq | GDP | DNA-directed DNA polymerase | / | 0.441 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.441 | |
| 1eir | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.441 | |
| 1fcx | 184 | Retinoic acid receptor gamma | / | 0.441 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.441 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1q4x | G24 | Thyroid hormone receptor beta | / | 0.441 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.441 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.441 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.441 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.441 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.441 | |
| 2p6l | SAH | Diphthine synthase | / | 0.441 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.441 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3hfb | ML4 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.441 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.441 | |
| 3pcn | DHY | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.441 | |
| 3pcn | DHY | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.441 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.441 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.441 | |
| 4ie0 | PD2 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.441 | |
| 4krs | 1SX | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 4l7h | 1W1 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4qxm | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.441 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 5a3b | APR | SIR2 family protein | / | 0.441 | |
| 5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.441 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.440 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.440 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.440 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.440 | |
| 2dsh | SAH | Diphthine synthase | / | 0.440 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.440 | |
| 3fr8 | NDP | Ketol-acid reductoisomerase, chloroplastic | 1.1.1.86 | 0.440 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3gb4 | D3M | DdmC | / | 0.440 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3nhx | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.440 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.440 | |
| 4gt8 | ADP | Sensor protein VraS | 2.7.13.3 | 0.440 | |
| 4j1c | 1HO | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.440 | |
| 4l3q | 926 | Glucokinase | 2.7.1.2 | 0.440 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.440 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.440 |