sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1oho | EQU | Steroid Delta-isomerase | 5.3.3.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1oho | EQU | Steroid Delta-isomerase | 5.3.3.1 | 1.000 | |
| 1gs3 | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.684 | |
| 3ows | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.617 | |
| 1cqs | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.601 | |
| 1ogx | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.590 | |
| 1e3r | AND | Steroid Delta-isomerase | 5.3.3.1 | 0.569 | |
| 3ipt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.566 | |
| 3owy | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.562 | |
| 3fzw | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.552 | |
| 1e3v | DXC | Steroid Delta-isomerase | 5.3.3.1 | 0.544 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.524 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.524 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.521 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.521 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.518 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.516 | |
| 1oh0 | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.511 | |
| 1w6y | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.511 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.511 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.507 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.506 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.503 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.503 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.503 | |
| 4ax8 | ADP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.503 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.503 | |
| 3up0 | D7S | aceDAF-12 | / | 0.502 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.502 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.502 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.501 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.501 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.500 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.499 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.499 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.499 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.499 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.498 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.498 | |
| 1osv | CHC | Bile acid receptor | / | 0.497 | |
| 3iog | SDF | Metallo-beta-lactamase type 2 | / | 0.497 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.496 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.495 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.495 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.495 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.494 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.494 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.494 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.494 | |
| 4l9q | 9TP | Serum albumin | / | 0.494 | |
| 1qjg | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.493 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.493 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.493 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.493 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.493 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.493 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.492 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.492 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.491 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.491 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.491 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.491 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.490 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.490 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.489 | |
| 4gtt | 7TQ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.489 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.488 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.488 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.488 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.488 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.488 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.487 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 3p9t | TCL | Repressor | / | 0.487 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.487 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.486 | |
| 4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.486 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.485 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.485 | |
| 4ymk | ST9 | Acyl-CoA desaturase 1 | / | 0.485 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.484 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.484 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.484 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.484 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.483 | |
| 1sre | HAB | Streptavidin | / | 0.483 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.483 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.483 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.483 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.482 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.482 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.482 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.482 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.482 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.482 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.481 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.481 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.481 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.480 | |
| 1swt | BTN | Streptavidin | / | 0.480 | |
| 2bxq | IMN | Serum albumin | / | 0.480 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.480 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.480 | |
| 3ov4 | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.480 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.480 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.480 | |
| 1lgt | BP3 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.479 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.479 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.479 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.479 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.478 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.478 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.478 | |
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.478 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.478 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.478 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.477 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.477 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.477 | |
| 3up3 | XCA | aceDAF-12 | / | 0.477 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.476 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.476 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.476 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.476 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.476 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4pb2 | 5UD | Nucleoside permease | / | 0.476 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.476 | |
| 2wcg | MT5 | Glucosylceramidase | 3.2.1.45 | 0.475 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.475 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.475 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.475 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.475 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.474 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.474 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.474 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.474 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.474 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.474 | |
| 3vgn | FNN | Steroid Delta-isomerase | 5.3.3.1 | 0.474 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.474 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.474 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.474 | |
| 1eio | GCH | Gastrotropin | / | 0.473 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.473 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.473 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.473 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.473 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.472 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 1srf | MTB | Streptavidin | / | 0.472 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.472 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.472 | |
| 3c1o | NAP | Eugenol synthase | / | 0.472 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.472 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.472 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.472 | |
| 1fel | FEN | Retinol-binding protein 4 | / | 0.471 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.471 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.471 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.471 | |
| 3ahi | HTL | Probable phosphoketolase | / | 0.471 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.471 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.471 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.471 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.471 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.471 | |
| 1q13 | TES | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.470 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 2lbd | REA | Retinoic acid receptor gamma | / | 0.470 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.470 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 2yat | EEU | Estrogen receptor | / | 0.470 | |
| 3zrb | OR8 | Progesterone receptor | / | 0.470 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.470 | |
| 1jum | BER | HTH-type transcriptional regulator QacR | / | 0.469 | |
| 2cah | NDP | Catalase | 1.11.1.6 | 0.469 | |
| 3nuv | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.469 | |
| 3rth | RTH | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.469 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.469 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.468 | |
| 1td2 | PXL | Pyridoxal kinase PdxY | / | 0.468 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.468 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.468 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.468 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.468 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.468 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.468 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.468 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.468 | |
| 4je5 | PLP | Aromatic/aminoadipate aminotransferase 1 | 2.6.1.39 | 0.468 | |
| 4lb2 | DM5 | Serum albumin | / | 0.468 | |
| 4u95 | MIY | Multidrug efflux pump subunit AcrB | / | 0.468 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.468 | |
| 1brp | RTL | Retinol-binding protein 4 | / | 0.467 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.467 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.467 | |
| 2zym | ACX | Periplasmic binding protein | / | 0.467 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.467 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.467 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.467 | |
| 4a33 | PS8 | Glycylpeptide N-tetradecanoyltransferase | / | 0.467 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.467 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.467 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.467 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.466 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.466 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.466 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.466 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.466 | |
| 2oyf | IAC | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.466 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.466 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 3fnu | 006 | HAP protein | / | 0.466 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.466 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.465 | |
| 2hxd | DUP | dCTP deaminase, dUMP-forming | 3.5.4.30 | 0.465 | |
| 3bgi | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.465 | |
| 3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.465 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.465 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.465 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.465 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.465 | |
| 4rrc | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.465 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.465 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.464 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.464 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.464 | |
| 1xxj | UNC | Uricase | 1.7.3.3 | 0.464 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.464 | |
| 2nxe | SAM | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.464 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.464 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.464 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.464 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.464 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.464 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.463 | |
| 1e7a | PFL | Serum albumin | / | 0.463 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.463 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.463 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.463 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.463 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.463 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.463 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.463 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.462 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.462 | |
| 1kt5 | RTL | Retinol-binding protein 4 | / | 0.462 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.462 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.462 | |
| 2cl5 | BIE | Catechol O-methyltransferase | 2.1.1.6 | 0.462 | |
| 2oli | IOP | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.462 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.462 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.461 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.461 | |
| 1u2r | SO1 | Elongation factor 2 | / | 0.461 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.461 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.461 | |
| 2hvc | LGD | Androgen receptor | / | 0.461 | |
| 2jfz | 003 | Glutamate racemase | / | 0.461 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.461 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 3w8z | HTK | Putative FAD-dependent oxygenase EncM | / | 0.461 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.461 | |
| 4l8u | 9AZ | Serum albumin | / | 0.461 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.460 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.460 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.460 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.460 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.460 | |
| 2a5c | 8DA | Avidin | / | 0.460 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 4c2p | X8Z | Angiotensin-converting enzyme | 3.2.1 | 0.460 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.460 | |
| 4eb4 | UMP | Thymidylate synthase | 2.1.1.45 | 0.460 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.460 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.459 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.459 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.459 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.459 | |
| 1tkb | N1T | Transketolase 1 | 2.2.1.1 | 0.459 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.459 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.459 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.459 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.459 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.459 | |
| 4hwk | SFY | Sepiapterin reductase | 1.1.1.153 | 0.459 | |
| 4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.459 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.459 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.459 | |
| 1eir | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.458 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.458 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.458 | |
| 1pua | COA | HAT A1 | / | 0.458 | |
| 1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.458 | |
| 1uhh | CZP | Aequorin-2 | / | 0.458 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.458 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.458 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.458 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3kxo | KXO | Hematopoietic prostaglandin D synthase | / | 0.458 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3nfr | EWQ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.458 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.458 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.458 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.458 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.458 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.458 | |
| 5epo | TUD | 7-alpha-hydroxysteroid deydrogenase | / | 0.458 | |
| 1axw | MTX | Thymidylate synthase | / | 0.457 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.457 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.457 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.457 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.457 | |
| 2uup | LK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.457 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.457 | |
| 2y67 | N21 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.457 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.457 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 3lm4 | HPX | Catechol 2,3-dioxygenase | / | 0.457 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.457 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.457 | |
| 4trj | 665 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.456 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.456 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.456 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.456 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.456 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3e7i | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.456 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.456 | |
| 3fsu | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.456 | |
| 3nhp | HGZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.456 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.456 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.456 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.456 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.455 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.455 | |
| 1i9h | BNI | Streptavidin | / | 0.455 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.455 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.455 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.455 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.455 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4iae | 1DX | Alr2278 protein | / | 0.455 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.455 | |
| 5dhg | DGV | Nociceptin receptor | / | 0.455 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.454 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1s36 | CEI | Obelin | / | 0.454 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.454 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.454 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.454 | |
| 3acy | 702 | Dehydrosqualene synthase | / | 0.454 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.454 | |
| 3c3e | FO1 | 2-phospho-L-lactate transferase | / | 0.454 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.454 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.454 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.454 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.454 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.454 | |
| 4ez7 | 2AN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.454 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.454 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4n1g | CEI | Obelin | / | 0.454 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 1h9z | RWF | Serum albumin | / | 0.453 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.453 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.453 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.453 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.453 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.453 | |
| 2acw | UPG | Glycosyltransferase | / | 0.453 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.453 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.453 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.453 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.453 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.453 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.453 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.453 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.453 | |
| 4exs | X8Z | Metallo-beta-lactamase type 2 | / | 0.453 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.453 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.453 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.453 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.453 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.453 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.453 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.452 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.452 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.452 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.452 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.452 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 1zpr | CB3 | Thymidylate synthase | / | 0.452 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.452 | |
| 3d76 | NBB | Pheromone-binding protein ASP1 | / | 0.452 | |
| 3e6c | 3C4 | Cyclic nucleotide-binding protein | / | 0.452 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.452 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.452 | |
| 3ox2 | 79X | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.452 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.452 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.452 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.452 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.452 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.451 | |
| 1tg2 | H2B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.451 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.451 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.451 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 3fmz | 2T1 | Retinol-binding protein 4 | / | 0.451 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.451 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.451 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.451 | |
| 3q2m | CKI | Spectinomycin phosphotransferase | / | 0.451 | |
| 3rme | RME | Acidic mammalian chitinase | 3.2.1.14 | 0.451 | |
| 3tpt | ADP | Serine/threonine-protein kinase toxin HipA | / | 0.451 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.451 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.450 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.450 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1m9j | CLW | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.450 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.450 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.450 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.450 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.450 | |
| 2gzl | 2AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.450 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.450 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2qds | MCO | Metallo-beta-lactamase type 2 | / | 0.450 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.450 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.450 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.450 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.450 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.450 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.450 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3ghh | 2NF | CD38 molecule | / | 0.450 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 4e6a | 0O9 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.450 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.450 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.449 | |
| 1ddu | DDU | Thymidylate synthase | / | 0.449 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.449 | |
| 1kt4 | RTL | Retinol-binding protein 4 | / | 0.449 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.449 | |
| 1pwu | GM6 | Lethal factor | 3.4.24.83 | 0.449 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.449 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.449 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.449 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 2ab2 | SNL | Mineralocorticoid receptor | / | 0.449 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 2g72 | F21 | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.449 | |
| 2j9g | ADP | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.449 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.449 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.449 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.449 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.449 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.449 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.449 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.449 | |
| 4mm9 | FVX | Na(+):neurotransmitter symporter (Snf family) | / | 0.449 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.449 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.449 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.449 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 1gs4 | ZK5 | Androgen receptor | / | 0.448 | |
| 1k9s | FM2 | Purine nucleoside phosphorylase DeoD-type | / | 0.448 | |
| 1lrh | NLA | Auxin-binding protein 1 | / | 0.448 | |
| 1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.448 | |
| 1sri | DMB | Streptavidin | / | 0.448 | |
| 1th6 | OIN | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.448 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 2hzq | STR | Apolipoprotein D | / | 0.448 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.448 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.448 | |
| 2rtd | BTN | Streptavidin | / | 0.448 | |
| 2rtk | GLL | Streptavidin | / | 0.448 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.448 | |
| 3cgy | RDC | Virulence sensor histidine kinase PhoQ | 2.7.13.3 | 0.448 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.448 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.448 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.448 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.448 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.448 | |
| 3w2e | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 3zra | ORB | Progesterone receptor | / | 0.448 | |
| 4dkb | DUN | Deoxyuridine triphosphatase, putative | / | 0.448 | |
| 4iah | 1DX | Alr2278 protein | / | 0.448 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.448 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.448 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.448 | |
| 1db5 | 6IN | Phospholipase A2, membrane associated | / | 0.447 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.447 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.447 | |
| 1ga8 | UPF | LgtC | / | 0.447 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.447 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.447 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2rab | NAD | Glutathione amide reductase | / | 0.447 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2x20 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.447 | |
| 2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.447 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.447 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.447 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.447 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.447 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.447 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.447 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.447 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.447 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.447 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.447 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.447 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.447 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4mmf | 29Q | Na(+):neurotransmitter symporter (Snf family) | / | 0.447 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.447 | |
| 5k8b | PDG | 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase | / | 0.447 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.447 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.447 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.446 | |
| 1mlz | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.446 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1rti | HEF | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.446 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.446 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.446 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.446 | |
| 2ilu | NDP | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.446 | |
| 2mji | KTR | Fatty acid-binding protein, intestinal | / | 0.446 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.446 | |
| 2wvl | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.446 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.446 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.446 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.446 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.446 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.446 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.446 | |
| 3kt8 | LTN | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.446 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.446 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.446 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.446 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.446 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.446 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.445 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.445 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.445 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.445 | |
| 1u72 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.445 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.445 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.445 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.445 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3hy3 | 10F | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.445 | |
| 3jqc | JU2 | Pteridine reductase, putative | / | 0.445 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.445 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.445 | |
| 4b1f | KRH | Glutamate racemase | / | 0.445 | |
| 4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.445 | |
| 4hmb | PZZ | Phospholipase A2 VRV-PL-VIIIa | / | 0.445 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.445 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.445 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.445 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.445 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.444 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.444 | |
| 1qsn | COA | HAT A1 | / | 0.444 | |
| 1syn | F89 | Thymidylate synthase | / | 0.444 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.444 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.444 | |
| 1w22 | NHB | Histone deacetylase 8 | 3.5.1.98 | 0.444 | |
| 1x2b | STX | Proline iminopeptidase | 3.4.11.5 | 0.444 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.444 | |
| 1zp4 | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.444 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.444 | |
| 2oth | NIM | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.444 | |
| 2vk8 | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.444 | |
| 2y37 | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.444 | |
| 3drr | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.444 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.444 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.444 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 3zrb | ORC | Progesterone receptor | / | 0.444 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.444 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.444 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.444 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.444 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.444 | |
| 5fmm | MGT | Polymerase basic protein 2 | / | 0.444 | |
| 5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.444 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 1fml | RTL | Retinol dehydratase | / | 0.443 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.443 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1n0u | SO1 | Elongation factor 2 | / | 0.443 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.443 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.443 | |
| 1srj | NAB | Streptavidin | / | 0.443 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 2ido | TMP | DNA polymerase III subunit epsilon | 2.7.7.7 | 0.443 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.443 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.443 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.443 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 3fu5 | 492 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.443 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.443 | |
| 3s6a | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.443 | |
| 3ssm | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.443 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 3zr7 | OR8 | Progesterone receptor | / | 0.443 | |
| 4at2 | ASD | Possible succinate dehydrogenase | / | 0.443 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4c1f | X8Z | Metallo-beta-lactamase type 2 | / | 0.443 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.443 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.443 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.443 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.443 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.443 | |
| 1aqb | RTL | Retinol-binding protein 4 | / | 0.442 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.442 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.442 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.442 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1hni | AAA | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.442 | |
| 1lke | DOG | Bilin-binding protein | / | 0.442 | |
| 1o2e | ANN | Phospholipase A2 | 3.1.1.4 | 0.442 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.442 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1sqn | NDR | Progesterone receptor | / | 0.442 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.442 | |
| 1tys | TMP | Thymidylate synthase | / | 0.442 | |
| 1tys | DHF | Thymidylate synthase | / | 0.442 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.442 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.442 | |
| 2rto | IMI | Streptavidin | / | 0.442 | |
| 2uz2 | BTN | Avd protein | / | 0.442 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.442 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.442 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4gnc | ASO | Regucalcin | 3.1.1.17 | 0.442 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.442 | |
| 4kyk | IMN | Lactoylglutathione lyase | 4.4.1.5 | 0.442 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 4n1f | CZH | Obelin | / | 0.442 | |
| 4qof | FMN | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.442 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.442 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.441 | |
| 1enp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.441 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 1m8d | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.441 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.441 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.441 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.441 | |
| 1zz1 | SHH | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.441 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.441 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.441 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 2xvv | 9DN | Serum albumin | / | 0.441 | |
| 2xvw | 9NR | Serum albumin | / | 0.441 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.441 | |
| 3dmj | GWE | Pol protein | / | 0.441 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.441 | |
| 3h18 | PMS | Esterase/lipase | / | 0.441 | |
| 3hx3 | RET | Retinaldehyde-binding protein 1 | / | 0.441 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.441 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.441 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.441 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 3r1r | ATP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.441 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.441 | |
| 3w0u | HPW | Lactoylglutathione lyase | 4.4.1.5 | 0.441 | |
| 4e5o | UMP | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 4lg5 | A1O | Abscisic acid receptor PYL2 | / | 0.441 | |
| 4oic | A8S | Bet v I allergen-like | / | 0.441 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.441 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4uda | DEX | Mineralocorticoid receptor | / | 0.441 | |
| 4wlj | IK2 | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.441 | |
| 1bzm | MZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.440 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1e3k | R18 | Progesterone receptor | / | 0.440 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.440 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.440 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
| 1uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.440 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.440 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2jbl | SMA | Reaction center protein L chain | / | 0.440 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.440 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3ujl | A8S | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.440 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.440 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.440 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.440 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 |