sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 1.000 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.651 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.638 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.519 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.509 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.509 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.509 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.503 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.503 | |
| 3wid | NAP | Glucose 1-dehydrogenase | / | 0.502 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.500 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.500 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.500 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.500 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.499 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.498 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.498 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.498 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.497 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.497 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.497 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.496 | |
| 2vj6 | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.495 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.495 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.495 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.495 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.494 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.493 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.493 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.493 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.493 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.493 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.492 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.492 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.492 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.492 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.491 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.491 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.490 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.490 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.489 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.489 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.489 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.489 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.489 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.489 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.489 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.489 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.488 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.488 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.486 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.486 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.486 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.486 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.486 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.486 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.486 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.486 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.485 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.485 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.484 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.484 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.483 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.483 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.483 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.482 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.482 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.482 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.482 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.482 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.482 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.481 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.481 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.480 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.480 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.480 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.480 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.479 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.479 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.479 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.479 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.479 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.479 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.479 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.479 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.479 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.478 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.478 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.478 | |
| 3pi5 | 3P5 | Beta-secretase 1 | 3.4.23.46 | 0.478 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.478 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.478 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.478 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.477 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.477 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.477 | |
| 2qtc | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.477 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.477 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.477 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.477 | |
| 4jic | FMN | GTN Reductase | / | 0.477 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.476 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.476 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.476 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.476 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.476 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.476 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.476 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.476 | |
| 3r2f | PB0 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.475 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.475 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.475 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.475 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.475 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.475 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.475 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.474 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.474 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.474 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.474 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.474 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.474 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.474 | |
| 4kcf | AKM | FAD-dependent oxidoreductase | / | 0.474 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.473 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 5ftf | ADP | TPR domain protein | / | 0.473 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.472 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.472 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.472 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.472 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.472 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.472 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.472 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.472 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.472 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.472 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.471 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.471 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.471 | |
| 2xy3 | DUP | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.471 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.471 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.471 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.471 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.471 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.471 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.471 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.471 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.470 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.470 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.470 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.470 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.470 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.470 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 3dv1 | AR9 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.470 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.470 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.469 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 2oah | QIN | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.469 | |
| 3eku | CY9 | Actin-5C | / | 0.469 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.469 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.469 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.469 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.468 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.468 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.468 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.468 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.468 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.468 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.468 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.468 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.468 | |
| 2g94 | ZPQ | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.468 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.468 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.468 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.468 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.468 | |
| 3v2u | ATP | Protein GAL3 | / | 0.468 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.468 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.468 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.467 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.467 | |
| 2wf2 | ZY2 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.467 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.467 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.467 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.467 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.467 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.467 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.466 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.466 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.466 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.466 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.466 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.466 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.466 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.465 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.465 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.465 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.464 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.464 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.464 | |
| 1nqw | 5YL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.464 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.464 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.464 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.464 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.464 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.464 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.464 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.464 | |
| 3wag | TYD | Glycosyltransferase | / | 0.464 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.464 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.464 | |
| 4ohw | ATP | Protein clpf-1 | / | 0.464 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.464 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.463 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.463 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.463 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.463 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.463 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.463 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.463 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.463 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.463 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.463 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.462 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.462 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.462 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.462 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.462 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.462 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.462 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.462 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.462 | |
| 1c7o | PPG | Hemolysin | / | 0.461 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.461 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.461 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.461 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.461 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.461 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.461 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.461 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.461 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.461 | |
| 2ohv | NHL | Glutamate racemase | / | 0.461 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.461 | |
| 3eks | CY9 | Actin-5C | / | 0.461 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.461 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.461 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.461 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.461 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.461 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.460 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.460 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.460 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.460 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.460 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.460 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.460 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.460 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.460 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.460 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.460 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.460 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.460 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.459 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.459 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.459 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.459 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.459 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.459 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.459 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.459 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.459 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.459 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.459 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.459 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.459 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.459 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.459 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.459 | |
| 4p63 | NAD | Probable deoxyhypusine synthase | 2.5.1.46 | 0.459 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.459 | |
| 8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.458 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.458 | |
| 1pz0 | NAP | Protein IolS | 1.1.1 | 0.458 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.458 | |
| 2e77 | FMN | Lactate oxidase | / | 0.458 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.458 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.458 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.458 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.458 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.458 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.458 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.458 | |
| 5dp2 | NAP | CurF | / | 0.458 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.458 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.457 | |
| 1o29 | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.457 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.457 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.457 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.457 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.457 | |
| 3u9e | COA | Lmo1369 protein | / | 0.457 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.457 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.457 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.457 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 4lrl | TTP | HD domain protein | / | 0.457 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.457 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.457 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.456 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.456 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 1qy5 | NEC | Endoplasmin | / | 0.456 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.456 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.456 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.456 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 3a3g | DLZ | Lumazine protein | / | 0.456 | |
| 3c21 | 2BA | DNA integrity scanning protein DisA | / | 0.456 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.456 | |
| 3t7s | SAM | Uncharacterized protein | / | 0.456 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.456 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.456 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.456 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.456 | |
| 4p53 | NAI | 2-epi-5-epi-valiolone synthase | / | 0.456 | |
| 4y7c | NAP | NADPH--cytochrome P450 reductase | / | 0.456 | |
| 5c41 | ACP | Ribokinase | / | 0.456 | |
| 5ebu | FMN | Lactate oxidase | / | 0.456 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.456 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.455 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.455 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.455 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.455 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.455 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.455 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 2x92 | X92 | Angiotensin-converting enzyme | 3.4.15.1 | 0.455 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.455 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.455 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.455 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.455 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.455 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.455 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.454 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.454 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.454 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.454 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.454 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.454 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.454 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.454 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.454 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.454 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.454 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.454 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3gnv | XNZ | Genome polyprotein | 2.7.7.48 | 0.454 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.454 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.454 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.454 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 4rnx | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.454 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.454 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.453 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.453 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.453 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 2ha8 | SAH | Probable methyltransferase TARBP1 | / | 0.453 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.453 | |
| 2wf0 | ZY0 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3fzf | ATP | Heat shock cognate 71 kDa protein | / | 0.453 | |
| 3iaa | TYD | CalG2 | / | 0.453 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.453 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.453 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.453 | |
| 4fdu | IHS | Putative multiple inositol polyphosphate histidine phosphatase 1 | / | 0.453 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.453 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.453 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.453 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.453 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.452 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.452 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.452 | |
| 2vnn | CM7 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.452 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.452 | |
| 3d3x | ARG_ILE_MET_GLU_NH2 | Type E botulinum toxin | / | 0.452 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.452 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.452 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.452 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.452 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.452 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.452 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.452 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.452 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.451 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.451 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.451 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.451 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.451 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.451 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.451 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.451 | |
| 2iiq | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.451 | |
| 2p4j | 23I | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.451 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.451 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.451 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.451 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.451 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.451 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.451 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.451 | |
| 4gsu | DWZ | L,D-transpeptidase 2 | 2.3.2 | 0.451 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.451 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.451 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.451 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.450 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.450 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.450 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.450 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.450 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.450 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.450 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.450 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.450 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.450 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.450 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.450 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.450 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.450 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.450 | |
| 4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.450 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.450 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.450 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.449 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.449 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.449 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.449 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.449 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.449 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.449 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.449 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.449 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.449 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.449 | |
| 3gr8 | FMN | NADPH dehydrogenase | / | 0.449 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.449 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.449 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.449 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.449 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.449 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.449 | |
| 4fkz | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.449 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.449 | |
| 4gi5 | FAD | Putative NAD(P)H dehydrogenase (Quinone) | / | 0.449 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.449 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.449 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.449 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.449 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.449 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.448 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.448 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.448 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.448 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.448 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.448 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.448 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.448 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.448 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.448 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.448 | |
| 4bxk | 1IU | Angiotensin-converting enzyme | 3.2.1 | 0.448 | |
| 4eu5 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.448 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.448 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.448 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.448 | |
| 4xr9 | NAD | CalS8 | / | 0.448 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.448 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.448 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.448 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.447 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1vza | UMP | Thymidylate synthase | / | 0.447 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.447 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.447 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.447 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.447 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.447 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.447 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.447 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.447 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.447 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.447 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.447 | |
| 3ieu | GDP | GTPase Era | / | 0.447 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3uce | NDP | Dehydrogenase | / | 0.447 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.447 | |
| 4djx | 0KQ | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.447 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.447 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.447 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.447 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.447 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.447 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.447 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.447 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.447 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.447 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.447 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.446 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.446 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.446 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.446 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.446 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.446 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 2qs4 | LY5 | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.446 | |
| 2zr9 | DTP | Protein RecA | / | 0.446 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.446 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.446 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.446 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.446 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.446 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.446 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.446 | |
| 3ohf | 3HF | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.446 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.446 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.446 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.446 | |
| 4lut | DCS | Alanine racemase | / | 0.446 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.446 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.446 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.446 | |
| 1az2 | NAP | Aldose reductase | 1.1.1.21 | 0.445 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 1o86 | LPR | Angiotensin-converting enzyme | 3.2.1 | 0.445 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.445 | |
| 2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.445 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.445 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.445 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.445 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.445 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.445 | |
| 2qjo | NAD | Bifunctional NMN adenylyltransferase/Nudix hydrolase | 2.7.7.1 | 0.445 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.445 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.445 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.445 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.445 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.445 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3cwq | ADP | ParA family chromosome partitioning protein | / | 0.445 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.445 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.445 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.445 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.445 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.445 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.445 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.445 | |
| 1bp6 | UMP | Thymidylate synthase | / | 0.444 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.444 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.444 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2ejz | SAH | Diphthine synthase | / | 0.444 | |
| 2f3f | AXF | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.444 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.444 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.444 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.444 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.444 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.444 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.444 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3r96 | ACO | MccE protein | / | 0.444 | |
| 3swc | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.444 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.444 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.444 | |
| 4ybr | NAP | Probable nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.444 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.444 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.443 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.443 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.443 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.443 | |
| 2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.443 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.443 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.443 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.443 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.443 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.443 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.443 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.443 | |
| 4az3 | S35 | Lysosomal protective protein | 3.4.16.5 | 0.443 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.443 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.443 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.443 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.443 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.443 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.443 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.443 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.443 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.443 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.443 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.443 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.443 | |
| 1kor | ANP | Argininosuccinate synthase | / | 0.442 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.442 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 1q43 | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.442 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.442 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.442 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.442 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.442 | |
| 2o8j | SAH | Histone-lysine N-methyltransferase EHMT2 | / | 0.442 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.442 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.442 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.442 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.442 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.442 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.442 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.442 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.442 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.442 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.442 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.442 | |
| 4rxq | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.442 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.442 | |
| 5ahs | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.441 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1p0f | NAP | NADP-dependent alcohol dehydrogenase | 1.1.1.2 | 0.441 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.441 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.441 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.441 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.441 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.441 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.441 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.441 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.441 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.441 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.441 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.441 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.441 | |
| 3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4frj | DWB | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4h1q | 0XX | Matrix metalloproteinase-9 | 3.4.24.35 | 0.441 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.441 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.441 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.441 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.440 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.440 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1z41 | FMN | NADPH dehydrogenase | / | 0.440 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.440 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.440 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.440 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.440 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.440 | |
| 3fpa | DTB | ATP-dependent dethiobiotin synthetase BioD | / | 0.440 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.440 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.440 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.440 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.440 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.440 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.440 | |
| 4b00 | I6X | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.440 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.440 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.440 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.440 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.440 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4qg1 | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 | |
| 4to0 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 | |
| 5cyo | GDP | Septin-9 | / | 0.440 |