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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4nbb9CATerminal oxygenase component of carbazole

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4nbb9CATerminal oxygenase component of carbazole/1.000
4nbh9CATerminal oxygenase component of carbazole/0.650
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.519
2b35TCLEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.519
1rkhVD2Vitamin D3 receptor/0.518
3w0hW12Vitamin D3 receptor/0.506
1e7aPFLSerum albumin/0.503
1txiTX5Vitamin D3 receptor/0.503
3kpzZNEVitamin D3 receptor/0.500
4rujVDXVitamin D3 receptor A/0.500
1e3kR18Progesterone receptor/0.499
2aaxPDNMineralocorticoid receptor/0.498
2hl2SSAThreonine--tRNA ligase6.1.1.30.498
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.498
3zraORBProgesterone receptor/0.498
3u8hBHPPhospholipase A2, membrane associated/0.497
4iteTEYVitamin D3 receptor/0.497
1ny2ARG_PRO_PRO_GLYProthrombin3.4.21.50.496
4rupH97Vitamin D3 receptor A/0.496
2hasC3OVitamin D3 receptor/0.495
3w5q3KLVitamin D3 receptor/0.495
2zlcVDXVitamin D3 receptor/0.494
3fu9KIBLaccase-11.10.3.20.494
3zloX8UBcl-2-like protein 1/0.494
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.493
3h0a9RARetinoic acid receptor RXR-alpha/0.493
1axwMTXThymidylate synthase/0.492
2hb7O1CVitamin D3 receptor/0.492
3uvvREARetinoic acid receptor RXR-alpha/0.491
1upw444Oxysterols receptor LXR-beta/0.490
1wsvTHHAminomethyltransferase, mitochondrial/0.490
2wgjVGHHepatocyte growth factor receptor2.7.10.10.490
4ia1BIVVitamin D3 receptor A/0.490
4wa9AXITyrosine-protein kinase ABL12.7.10.20.490
1kmvLIIDihydrofolate reductase1.5.1.30.489
2hamC33Vitamin D3 receptor/0.489
4g1y0VOVitamin D3 receptor A/0.489
4zm6ACON-acetyl-beta-D glucosaminidase/0.489
1zgv501Prothrombin3.4.21.50.488
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.488
5k7uSAMN6-adenosine-methyltransferase 70 kDa subunit/0.488
2aa2AS4Mineralocorticoid receptor/0.487
2hc4VDXVitamin D3 receptor A/0.487
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.487
2wd8VGFPteridine reductase/0.487
3vt3VDXVitamin D3 receptor/0.487
3vt5YI2Vitamin D3 receptor/0.487
3vtbTKAVitamin D3 receptor/0.487
3zbx6XEHepatocyte growth factor receptor2.7.10.10.487
1rdtL79Retinoic acid receptor RXR-alpha/0.486
1z1fSTLResveratrol synthase/0.486
2a3iC0RMineralocorticoid receptor/0.486
2o4jVD4Vitamin D3 receptor/0.486
3fu83DMLaccase-11.10.3.20.486
4egnTWOCytochrome P450/0.486
4ia3BIVVitamin D3 receptor A/0.486
2oaxSNLMineralocorticoid receptor/0.485
3dyaPZLGag-Pol polyprotein2.7.7.490.485
4g2h0VQVitamin D3 receptor A/0.485
1s19MC9Vitamin D3 receptor/0.484
2a5yATPCell death protein 4/0.484
2hb8MVDVitamin D3 receptor/0.484
2o4rVD5Vitamin D3 receptor/0.484
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.484
4g1z0VPVitamin D3 receptor A/0.484
5uviZMAAdenosine receptor A2a/0.484
1fkoEFZGag-Pol polyprotein2.7.7.490.483
1jtqLY3Thymidylate synthase/0.483
1l0lFMXCytochrome b/0.483
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.483
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.483
4itfTFYVitamin D3 receptor/0.483
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.483
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.482
3a4pDFQHepatocyte growth factor receptor2.7.10.10.482
3a783EVVitamin D3 receptor/0.482
4g20484Vitamin D3 receptor A/0.482
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.482
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.481
1p8dCO1Oxysterols receptor LXR-beta/0.481
2ovhAS0Progesterone receptor/0.481
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.481
3qakUKAAdenosine receptor A2a/0.481
2w6nOA2Biotin carboxylase6.3.4.140.480
3vt65YIVitamin D3 receptor/0.480
3w5p4OAVitamin D3 receptor/0.480
4l8u9AZSerum albumin/0.480
5h8tRTLRetinol-binding protein 1/0.480
1fm69CRRetinoic acid receptor RXR-alpha/0.479
1s0zEB1Vitamin D3 receptor/0.479
2xvv9DNSerum albumin/0.479
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.479
3vtdTKDVitamin D3 receptor/0.479
4f700STCyclin-dependent kinase 82.7.11.220.479
1fmlRTLRetinol dehydratase/0.478
1obnASVIsopenicillin N synthase1.21.3.10.478
3vtcTK3Vitamin D3 receptor/0.478
3zze6XPHepatocyte growth factor receptor2.7.10.10.478
4hlm16STankyrase-22.4.2.300.478
1hk5T44Serum albumin/0.477
2aa5STRMineralocorticoid receptor/0.477
2be2R22Gag-Pol polyprotein2.7.7.490.477
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.477
2zlaVDBVitamin D3 receptor/0.477
4fhh0U3Vitamin D3 receptor A/0.477
4gg70J8Hepatocyte growth factor receptor2.7.10.10.477
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.477
2v58LZJBiotin carboxylase6.3.4.140.476
3rg9WRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.476
3w0jT08Vitamin D3 receptor/0.476
1ie8KH1Vitamin D3 receptor/0.475
1mznBM6Retinoic acid receptor RXR-alpha/0.475
1rkgVD1Vitamin D3 receptor/0.475
1rszDIHPurine nucleoside phosphorylase2.4.2.10.475
2opsHBQGag-Pol polyprotein2.7.7.490.475
2p7zOHTEstrogen-related receptor gamma/0.475
2y60M8FIsopenicillin N synthase1.21.3.10.475
3q5pTACMultidrug-efflux transporter 1 regulator/0.475
3t3r9PLCytochrome P450 2A61.14.130.475
4ia7BIVVitamin D3 receptor A/0.475
4k6i9RARetinoic acid receptor RXR-alpha/0.475
4r21STRCytochrome P450 family 17 polypeptide 2/0.475
4rr9A3SProbable threonine--tRNA ligase 26.1.1.30.475
1m9jCLWNitric oxide synthase, endothelial1.14.13.390.474
1mczTDPBenzoylformate decarboxylase4.1.1.70.474
1nhz486Glucocorticoid receptor/0.474
2qpyDHTAndrogen receptor/0.474
2wkmPFYHepatocyte growth factor receptor2.7.10.10.474
3djfBC3Purine nucleoside phosphorylase/0.474
3dlgGWEGag-Pol polyprotein2.7.7.490.474
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.474
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.474
3w0yDS4Vitamin D3 receptor/0.474
1db1VDXVitamin D3 receptor/0.473
1opbRETRetinol-binding protein 2/0.473
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.473
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.473
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.473
3up0D7SaceDAF-12/0.473
4inb1F6Gag protein/0.473
4j6dTESCytochrome P450 monooxygenase/0.473
4lsjLSJGlucocorticoid receptor/0.473
4u0k744Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.473
1rjkVDZVitamin D3 receptor/0.472
1s9qOHTEstrogen-related receptor gamma/0.472
2aa71CAMineralocorticoid receptor/0.472
2xvw9NRSerum albumin/0.472
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.472
3vrtYS2Vitamin D3 receptor/0.472
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.472
4g210VPVitamin D3 receptor A/0.472
4k9yK9YFocal adhesion kinase 12.7.10.20.472
5bukFADFADH2-dependent halogenase/0.472
5iubCLRAdenosine receptor A2a/0.472
1c4vIH2Prothrombin3.4.21.50.471
1galFADGlucose oxidase1.1.3.40.471
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
3w0gW07Vitamin D3 receptor/0.471
4ia2BIVVitamin D3 receptor A/0.471
4pnmNU1Tankyrase-22.4.2.300.471
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.471
1rk3VDXVitamin D3 receptor/0.470
1zgaHMKIsoflavone 4'-O-methyltransferase/0.470
2ab2SNLMineralocorticoid receptor/0.470
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.470
2ydoADNAdenosine receptor A2a/0.470
3e5aVX6Aurora kinase A2.7.11.10.470
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.470
3jzfJZKBiotin carboxylase6.3.4.140.470
3pd5TSBThreonine--tRNA ligase6.1.1.30.470
3w5rLOAVitamin D3 receptor/0.470
4bu908CTankyrase-22.4.2.300.470
4ejgNCTCytochrome P450 2A131.14.14.10.470
3sn6P0GBeta-2 adrenergic receptor/0.470
1x8lOXRRetinol dehydratase/0.469
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.469
3ghh2NFCD38 molecule/0.469
3pd2A3SThreonine--tRNA ligase6.1.1.30.469
3u9y09LTankyrase-22.4.2.300.469
3vt7VDXVitamin D3 receptor/0.469
3w5tLHPVitamin D3 receptor/0.469
4bj9UHBTankyrase-22.4.2.300.469
4hnc0UTMandelate racemase/0.469
4ruoBIVVitamin D3 receptor A/0.469
1dnaCB3Thymidylate synthase/0.468
1synF89Thymidylate synthase/0.468
2aclREARetinoic acid receptor RXR-alpha/0.468
2fpcSCGStrictosidine synthase4.3.3.20.468
2imfTOM2-hydroxychromene-2-carboxylate isomerase5.99.1.40.468
2rhrEMOPutative ketoacyl reductase1.3.10.468
3ln1CELProstaglandin G/H synthase 21.14.99.10.468
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.468
4fw05KJNitric oxide synthase, brain1.14.13.390.468
4hkkAGITankyrase-22.4.2.300.468
4i9i1DYTankyrase-12.4.2.300.468
1ay0TPPTransketolase 12.2.1.10.467
1dduCB3Thymidylate synthase/0.467
1h51FMNPentaerythritol tetranitrate reductase/0.467
1t4v14AProthrombin3.4.21.50.467
2aa6STRMineralocorticoid receptor/0.467
2hcdBIVVitamin D3 receptor A/0.467
2p1u4TNRetinoic acid receptor RXR-alpha/0.467
2pirDHTAndrogen receptor/0.467
2zbaZBATrichothecene 3-O-acetyltransferase/0.467
3c14FOKAdenylate cyclase type 2/0.467
3c14FOKAdenylate cyclase type 5/0.467
3c1xCKKHepatocyte growth factor receptor2.7.10.10.467
3ipq965Oxysterols receptor LXR-alpha/0.467
3oafOAGDihydrofolate reductase1.5.1.30.467
3up3XCAaceDAF-12/0.467
3vrvYSDVitamin D3 receptor/0.467
4bfrJ82Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform2.7.1.1530.467
4fhi0S4Vitamin D3 receptor A/0.467
4mr51K0Bromodomain-containing protein 2/0.467
4o71CPBBromodomain-containing protein 4/0.467
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.466
1mvsDTMDihydrofolate reductase1.5.1.30.466
3fmz2T1Retinol-binding protein 4/0.466
3jpuTY4Transcriptional activator protein LasR/0.466
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.466
3pd4A3GThreonine--tRNA ligase6.1.1.30.466
3qviK95HAP protein/0.466
3vt9YI4Vitamin D3 receptor/0.466
4bcqTJFCyclin-dependent kinase 22.7.11.220.466
5k2bZMAAdenosine receptor A2a/0.466
1fmjRTLRetinol dehydratase/0.465
1jtuLYBThymidylate synthase/0.465
2gpvOHTEstrogen-related receptor gamma/0.465
2hl1A3SThreonine--tRNA ligase6.1.1.30.465
2ovmAS0Progesterone receptor/0.465
3angDCCTranscriptional repressor, TetR family/0.465
3ibqATPPyridoxal kinase/0.465
4ej1FOLDihydrofolate reductase1.5.1.30.465
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.465
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.465
4rrqA3SThreonine--tRNA ligase6.1.1.30.465
1hk4T44Serum albumin/0.464
1kzjCB3Thymidylate synthase/0.464
1v79FR7Adenosine deaminase3.5.4.40.464
2ahvCOAAcetate CoA-transferase YdiF2.8.3.80.464
2j62GSZO-GlcNAcase NagJ/0.464
3nlrJRSNitric oxide synthase, brain1.14.13.390.464
3nmpPYVAbscisic acid receptor PYL2/0.464
3q0vLL4HTH-type transcriptional regulator EthR/0.464
3qwkX62Cyclin-dependent kinase 22.7.11.220.464
3vg9ZMAAdenosine receptor A2a/0.464
3w0aDS5Vitamin D3 receptor/0.464
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.464
4bjx73BBromodomain-containing protein 4/0.464
4fvz4KJNitric oxide synthase, brain1.14.13.390.464
4pkl1GHUncharacterized protein/0.464
3emlZMAAdenosine receptor A2a/0.464
1jlaTNKGag-Pol polyprotein2.7.7.490.463
1m7aMQUDihydrofolate reductase1.5.1.30.463
1mczRMNBenzoylformate decarboxylase4.1.1.70.463
1umlFR4Adenosine deaminase3.5.4.40.463
2amb17HAndrogen receptor/0.463
2jb4A14Isopenicillin N synthase1.21.3.10.463
2mseGNPMHC class I alpha chain/0.463
2ociTYCValacyclovir hydrolase3.10.463
2r0g7CKPutative FAD-monooxygenase/0.463
2zjwREFCasein kinase II subunit alpha2.7.11.10.463
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.463
3dhbC6LN-acyl homoserine lactonase AiiA3.1.1.810.463
3nrcTCLEnoyl-[acyl-carrier-protein] reductase [NADH]/0.463
3zr7OR8Progesterone receptor/0.463
4dymIYZActivin receptor type-12.7.11.300.463
4jhiEMUNodulin-13/0.463
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.463
4rrxLURProstaglandin G/H synthase 21.14.99.10.463
1cf3FADGlucose oxidase1.1.3.40.462
1ci7CB3Thymidylate synthase2.1.1.450.462
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.462
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.462
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.462
1n5vNOMActVA 6 protein/0.462
1pd9CO4Dihydrofolate reductase1.5.1.30.462
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.462
1s3yTQTDihydrofolate reductase1.5.1.30.462
1vq1SAMRelease factor glutamine methyltransferase2.1.1.2970.462
2pklDHTAndrogen receptor/0.462
2zfr46UProthrombin3.4.21.50.462
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.462
3dolGWIPol protein/0.462
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.462
3t195MAGag-Pol polyprotein2.7.7.490.462
3vi7CBDHematopoietic prostaglandin D synthase/0.462
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.462
4hyf1AKTankyrase-22.4.2.300.462
4ok1198Androgen receptor/0.462
4q0a4OAVitamin D3 receptor A/0.462
5fliQUEQuercetinase QueD/0.462
5il2SAHN6-adenosine-methyltransferase 70 kDa subunit/0.462
1ejeFMNProtein MTH_152/0.461
1sqnNDRProgesterone receptor/0.461
1wxyFRKAdenosine deaminase3.5.4.40.461
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
2vbdV10Isopenicillin N synthase1.21.3.10.461
2w6pOA4Biotin carboxylase6.3.4.140.461
2xk730ESerine/threonine-protein kinase Nek22.7.11.10.461
2zb45OPProstaglandin reductase 21.3.1.480.461
2zhf49UProthrombin3.4.21.50.461
2znq401Peroxisome proliferator-activated receptor delta/0.461
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
3litE15Protease/0.461
3lkhLT6Genome polyprotein2.7.7.480.461
3w0c6DSVitamin D3 receptor/0.461
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.461
4l2yXXKPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.461
4pkwGM6Lethal factor3.4.24.830.461
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.461
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.461
5cyqT27Gag-Pol polyprotein2.7.7.490.461
1aiqCB3Thymidylate synthase/0.460
1m9k7NINitric oxide synthase, endothelial1.14.13.390.460
2h94FADLysine-specific histone demethylase 1A10.460
2hbhXE4Vitamin D3 receptor A/0.460
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.460
2qzsADPGlycogen synthase2.4.1.210.460
3bgiSAHThiopurine S-methyltransferase2.1.1.670.460
3d76NBBPheromone-binding protein ASP1/0.460
3h18PMSEsterase/lipase/0.460
3n8yDIFProstaglandin G/H synthase 11.14.99.10.460
3p8iFMNPentaerythritol tetranitrate reductase/0.460
3vt45YIVitamin D3 receptor/0.460
3vt8YI3Vitamin D3 receptor/0.460
3zrbORCProgesterone receptor/0.460
4apuOR8Progesterone receptor/0.460
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.460
4f3i0S6Bromodomain-containing protein 4/0.460
4h6pFMNChromate reductase/0.460
4i7fNVEGag-Pol polyprotein2.7.7.490.460
4li71XPTankyrase-12.4.2.300.460
4mt92D6Tankyrase-12.4.2.300.460
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.460
4rrfA3SThreonine--tRNA ligase6.1.1.30.460
1f5fDHTSex hormone-binding globulin/0.459
1g28FMNPHY3/0.459
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.459
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.459
2w71L23Biotin carboxylase6.3.4.140.459
2w8y486Progesterone receptor/0.459
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
3exnACOProbable acetyltransferase/0.459
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.459
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.459
4k4fK4FTankyrase-12.4.2.300.459
4rrwLURProstaglandin G/H synthase 21.14.99.10.459
4rrzLURProstaglandin G/H synthase 21.14.99.10.459
1diuBDMDihydrofolate reductase1.5.1.30.458
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.458
1mvcBM6Retinoic acid receptor RXR-alpha/0.458
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.458
1tsdF89Thymidylate synthase/0.458
1ve3SAMUncharacterized protein/0.458
2harOCCVitamin D3 receptor/0.458
2r0pK2CPutative FAD-monooxygenase/0.458
2ziq26UProthrombin3.4.21.50.458
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.458
3e7iB2Nitric oxide synthase, inducible1.14.13.390.458
3ns2PYVAbscisic acid receptor PYL2/0.458
3p9tTCLRepressor/0.458
3zrbOR8Progesterone receptor/0.458
4bchT7ZCyclin-dependent kinase 92.7.11.220.458
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4g1d0VKVitamin D3 receptor A/0.458
4k4eK4ETankyrase-12.4.2.300.458
4okt198Androgen receptor/0.458
4py6R78Bromodomain protein, putative/0.458
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.458
5k2cZMAAdenosine receptor A2a/0.458
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.457
1d6w00RProthrombin3.4.21.50.457
1e92HBIPteridine reductase 11.5.1.330.457
1kt5RTLRetinol-binding protein 4/0.457
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.457
1r35I58Nitric oxide synthase, inducible1.14.13.390.457
1s9pDESEstrogen-related receptor gamma/0.457
2bfpH4BPteridine reductase 11.5.1.330.457
2dhfDZFDihydrofolate reductase1.5.1.30.457
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.457
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.457
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.457
3c3ySAHO-methyltransferase/0.457
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3kmyD8YBeta-secretase 13.4.23.460.457
3p3zP3ZPutative cytochrome P450/0.457
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.457
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.457
3v49PK0Androgen receptor/0.457
4a9oA9OBromodomain-containing protein 2/0.457
4b1iA8PPoly(ADP-ribose) glycohydrolase3.2.1.1430.457
4g2i0VQVitamin D3 receptor/0.457
4rrcA3TProbable threonine--tRNA ligase 26.1.1.30.457
5c1mCLRMu-type opioid receptor/0.457
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
1ddtAPUDiphtheria toxin/0.456
1ppjANYCytochrome b/0.456
1t5zDHTAndrogen receptor/0.456
1tdcUMPThymidylate synthase/0.456
1trkTPPTransketolase 12.2.1.10.456
1tysDHFThymidylate synthase/0.456
1uy6PU3Heat shock protein HSP 90-alpha/0.456
1yhjR6CPyridoxal kinase2.7.1.350.456
2bbqPFGThymidylate synthase/0.456
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
3b9lAZZSerum albumin/0.456
3bqdDAYGlucocorticoid receptor/0.456
3r7kFDAProbable acyl CoA dehydrogenase/0.456
3s79ASDAromatase1.14.14.140.456
3znqSS8D-amino-acid oxidase1.4.3.30.456
4ead0NPThymidine phosphorylase2.4.2.40.456
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.456
4oh5HFTAndrogen receptor/0.456
4pabTHGDimethylglycine dehydrogenase, mitochondrial1.5.8.40.456
4relKMPGlycosyltransferase/0.456
5jtbZMAAdenosine receptor A2a/0.456
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.455
1wdkACO3-ketoacyl-CoA thiolase/0.455
1yhoTRRDihydrofolate reductase1.5.1.30.455
2bxmIMNSerum albumin/0.455
2hr8SAHDiphthine synthase/0.455
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
2pioDHTAndrogen receptor/0.455
2vgoAD5Aurora kinase B-A2.7.11.10.455
2w3aTOPDihydrofolate reductase1.5.1.30.455
3bhtMFRCyclin-dependent kinase 22.7.11.220.455
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.455
3d90NOGProgesterone receptor/0.455
3fc6REARetinoic acid receptor RXR-alpha/0.455
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
3hk1B64Fatty acid-binding protein, adipocyte/0.455
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
3pqbVGPPutative oxidoreductase/0.455
4bcmT7ZCyclin-dependent kinase 22.7.11.220.455
4ds8A8SAbscisic acid receptor PYL3/0.455
4g95OAGDihydrofolate reductase1.5.1.30.455
4la7A1OAbscisic acid receptor PYL2/0.455
4ofrDHTAndrogen receptor/0.455
4udaDEXMineralocorticoid receptor/0.455
1bozPRDDihydrofolate reductase1.5.1.30.454
1ie9VDXVitamin D3 receptor/0.454
1n83CLRNuclear receptor ROR-alpha/0.454
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
1ypkCCRProthrombin3.4.21.50.454
1zg32HIIsoflavone 4'-O-methyltransferase/0.454
2ao6R18Androgen receptor/0.454
2cchATPCyclin-dependent kinase 22.7.11.220.454
2p1v5TNRetinoic acid receptor RXR-alpha/0.454
2y37A54Nitric oxide synthase, inducible1.14.13.390.454
3aqaBYHBromodomain-containing protein 2/0.454
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
3fnhJPJEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
3iptEQUSteroid Delta-isomerase5.3.3.10.454
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.454
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.454
3pd3A3TThreonine--tRNA ligase6.1.1.30.454
3pm1ETHTH-type transcriptional regulator QacR/0.454
3q0uLL3HTH-type transcriptional regulator EthR/0.454
3qlzQLZUncharacterized protein/0.454
3zxzKRWHepatocyte growth factor receptor2.7.10.10.454
4haiI23Bifunctional epoxide hydrolase 23.1.3.760.454
4j1p1K0Bromodomain-containing protein 2/0.454
4jseQJ2Nitric oxide synthase, brain1.14.13.390.454
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
4mr61K0Bromodomain-containing protein 2/0.454
4uyg73BBromodomain-containing protein 2/0.454
4xmxBESAminopeptidase N3.4.11.20.454
5es7FONLinear gramicidin synthase subunit A/0.454
1kqwRTLCellular retinol-binding protein type II/0.453
1m52P17Tyrosine-protein kinase ABL12.7.10.20.453
1s3vTQDDihydrofolate reductase1.5.1.30.453
1ykdCMPAdenylate cyclase/0.453
2b5j3ACGag-Pol polyprotein2.7.7.490.453
2fjn073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.453
2jfaRALEstrogen receptor/0.453
2p1t3TNRetinoic acid receptor RXR-alpha/0.453
2tsrD16Thymidylate synthase2.1.1.450.453
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
2w6oOA3Biotin carboxylase6.3.4.140.453
2xkeWI2Serine/threonine-protein kinase Nek22.7.11.10.453
2z97CAMCamphor 5-monooxygenase1.14.15.10.453
3c6uM22Gag-Pol polyprotein2.7.7.490.453
3dmjGWEPol protein/0.453
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3h3t16HCollagen type IV alpha-3-binding protein/0.453
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
3w0iO11Vitamin D3 receptor/0.453
4a9iP9IBromodomain-containing protein 2/0.453
4iw8KN3Estrogen receptor/0.453
4mfb29TGag-Pol polyprotein2.7.7.490.453
4nteFADDepH/0.453
4ofuDHTAndrogen receptor/0.453
4qa0SHHHistone deacetylase 83.5.1.980.453
4udcDEXGlucocorticoid receptor/0.453
4ug91EWNitric oxide synthase oxygenase1.14.13.1650.453
5iu4ZMAAdenosine receptor A2a/0.453
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.452
1fm4DXCMajor pollen allergen Bet v 1-L/0.452
1hb1OCVIsopenicillin N synthase1.21.3.10.452
1hfqMOTDihydrofolate reductase1.5.1.30.452
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
1klkPMDDihydrofolate reductase1.5.1.30.452
1og5SWFCytochrome P450 2C9/0.452
1pq6965Oxysterols receptor LXR-beta/0.452
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.452
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.452
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.452
2ibyCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.452
2j9lATPH(+)/Cl(-) exchange transporter 5/0.452
2ph5NADHomospermidine synthase/0.452
2qimZEAClass 10 plant pathogenesis-related protein/0.452
2w8yNDRProgesterone receptor/0.452
3a60STURibosomal protein S6 kinase beta-12.7.11.10.452
3akm11DFatty acid-binding protein, intestinal/0.452
3c6tM14Gag-Pol polyprotein2.7.7.490.452
3d75NBBPheromone-binding protein ASP1/0.452
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.452
3dr1C5DVitamin D3 receptor A/0.452
3lfeZ84Mitogen-activated protein kinase 14/0.452
3nefPYVAbscisic acid receptor PYL1/0.452
3ntz3TZDihydrofolate reductase1.5.1.30.452
3pllF06Endothiapepsin3.4.23.220.452
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.452
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.452
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
4cdmFO1Deoxyribodipyrimidine photolyase/0.452
4dneDTBStreptavidin/0.452
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
4gqe6KJNitric oxide synthase, brain1.14.13.390.452
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.452
4ix5ANPUncharacterized protein/0.452
4otyLURProstaglandin G/H synthase 21.14.99.10.452
4twnB96Ephrin type-A receptor 32.7.10.10.452
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.452
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.452
1bsvNDPGDP-L-fucose synthase/0.451
1d4pBPPProthrombin3.4.21.50.451
1o6qR17Squalene--hopene cyclase4.2.1.1290.451
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.451
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.451
1uymPU3Heat shock protein HSP 90-beta/0.451
1y6aAAZVascular endothelial growth factor receptor 22.7.10.10.451
2on6IMHPurine nucleoside phosphorylase2.4.2.10.451
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
2v5aLZLBiotin carboxylase6.3.4.140.451
2wggTLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.451
2xk3XK3Serine/threonine-protein kinase Nek22.7.11.10.451
2yelWSHBromodomain-containing protein 4/0.451
3drrR8EGag-Pol polyprotein2.7.7.490.451
3fwjCAMCamphor 5-monooxygenase1.14.15.10.451
3hdyGDUUDP-galactopyranose mutase/0.451
3hz5Z64Heat shock protein HSP 90-alpha/0.451
3m7rVDXVitamin D3 receptor/0.451
3mqe416Prostaglandin G/H synthase 21.14.99.10.451
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.451
3vrwYS5Vitamin D3 receptor/0.451
4bfpSWYTankyrase-22.4.2.300.451
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.451
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.451
4dphP65Bifunctional dihydrofolate reductase-thymidylate synthase/0.451
4foxD16Thymidylate synthase ThyA/0.451
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.451
4j21AJ6Tankyrase-22.4.2.300.451
4jbsP52Endoplasmic reticulum aminopeptidase 23.4.110.451
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.451
4l9kEHFSerum albumin/0.451
4m6l21VDihydrofolate reductase1.5.1.30.451
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.451
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.450
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
1fwmCB3Thymidylate synthase/0.450
1fxsNAPGDP-L-fucose synthase/0.450
1ly4COQDihydrofolate reductase1.5.1.30.450
1nenDNTSuccinate dehydrogenase iron-sulfur subunit1.3.5.10.450
1nenDNTSuccinate dehydrogenase cytochrome b556 subunit/0.450
1r2jFADFkbI/0.450
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.450
1tvcFDAMethane monooxygenase component C1.14.13.250.450
2gniM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
2op18PCEnoyl-ACP reductase/0.450
3br3ETHTH-type transcriptional regulator QacR/0.450
3d0bSNXHeat shock protein HSP 90-alpha/0.450
3ddw055Glycogen phosphorylase, liver form2.4.1.10.450
3fp0FP015-O-acetyltransferase/0.450
3gkjHC3Niemann-Pick C1 protein/0.450
3i0rRT3Gag-Pol polyprotein2.7.7.490.450
3ii43IIDihydrolipoyl dehydrogenase1.8.1.40.450
3kxoKXOHematopoietic prostaglandin D synthase/0.450
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.450
3miaANPCyclin-dependent kinase 92.7.11.220.450
3tp0FO5HTH-type transcriptional regulator EthR/0.450
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
4enhFVXCholesterol 24-hydroxylase/0.450
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
4h0xNADIota toxin component Ia/0.450
4l1xSTRAldo-keto reductase family 1 member C2/0.450
4li61XOTankyrase-12.4.2.300.450
4oicA8SBet v I allergen-like/0.450
1culFOKAdenylate cyclase type 2/0.449
1culFOKAdenylate cyclase type 5/0.449
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1rl4BRRPeptide deformylase/0.449
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.449
1trgCB3Thymidylate synthase/0.449
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.449
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.449
2jibTPPOxalyl-CoA decarboxylase4.1.1.80.449
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.449
2pg0FADAcyl-CoA dehydrogenase/0.449
2q9fC3SCholesterol 24-hydroxylase/0.449
2r2mI50Prothrombin3.4.21.50.449
2rgbGNPGTPase HRas/0.449
2vb8TLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.449
2zymACXPeriplasmic binding protein/0.449
3friSAH16S rRNA methylase/0.449
3i8aN22Dihydrofolate reductase1.5.1.30.449
3mg3ECHOrange carotenoid-binding protein/0.449
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.449
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.449
3sa27DRDihydrofolate reductase/0.449
4a2aATPCell division protein FtsA/0.449
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.449
4alhA9PBromodomain-containing protein 2/0.449
4bw39BMBromodomain-containing protein 4/0.449
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
4ek1CAMCamphor 5-monooxygenase1.14.15.10.449
4idgNADPutative UDP-glucose 4-epimerase/0.449
4iqqD16Thymidylate synthase/0.449
4jbtASDCytochrome P450 monooxygenase/0.449
4l9wGNPGTPase HRas/0.449
4mv3ACPBiotin carboxylase6.3.4.140.449
4ohaHFTAndrogen receptor/0.449
4xclAGSHeat shock cognate 90 kDa protein/0.449
5bt42LOBromodomain-containing protein 4/0.449
5eq1BEAPeregrin/0.449
4uhrNGIAdenosine receptor A2a/0.449
1kyoSMACytochrome b/0.448
1m78NDPDihydrofolate reductase1.5.1.30.448
1m9m6NINitric oxide synthase, endothelial1.14.13.390.448
1pd8CO4Dihydrofolate reductase1.5.1.30.448
2f2cAP9Cyclin-dependent kinase 62.7.11.220.448
2fzjDH3Dihydrofolate reductase1.5.1.30.448
2g263LGRenin3.4.23.150.448
2gpuOHTEstrogen-related receptor gamma/0.448
2i40BLZCyclin-dependent kinase 22.7.11.220.448
2jedLG8Protein kinase C theta type2.7.11.130.448
2nnqT4BFatty acid-binding protein, adipocyte/0.448
2xk85R1Serine/threonine-protein kinase Nek22.7.11.10.448
3bejMUFBile acid receptor/0.448
3e01PZ2Gag-Pol polyprotein2.7.7.490.448
3f4bTCLEnoyl-acyl carrier protein reductase/0.448
3h3sH15Collagen type IV alpha-3-binding protein/0.448
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
3is9AC7Gag-Pol polyprotein2.7.7.490.448
3lanKBTGag-Pol polyprotein2.7.7.490.448
3negPYVAbscisic acid receptor PYL1/0.448
3oapREARetinoic acid receptor RXR-alpha/0.448
3oq6PFBAlcohol dehydrogenase E chain1.1.1.10.448
3oqkS52Renin3.4.23.150.448
3p5sAVUCD38 molecule/0.448
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.448
3wsjMK1Protease/0.448
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.448
4bb3KKAIsopenicillin N synthase1.21.3.10.448
4h9614QDihydrofolate reductase1.5.1.30.448
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.448
4jzr4JREgl nine homolog 1/0.448
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.448
4lgaA2OAbscisic acid receptor PYL2/0.448
4nmbFADBifunctional protein PutA/0.448
4qysPLRTryptophan synthase beta chain 24.2.1.200.448
4zp1TPPPyruvate decarboxylase4.1.1.10.448
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.448
5hbsRTLRetinol-binding protein 1/0.448
1al7HSTPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.447
1dyrTOPDihydrofolate reductase1.5.1.30.447
1gs4ZK5Androgen receptor/0.447
1ludTRRDihydrofolate reductase1.5.1.30.447
1ndyFR3Adenosine deaminase3.5.4.40.447
1qw514WNitric oxide synthase, inducible1.14.13.390.447
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.447
1t4u81AProthrombin3.4.21.50.447
1uhlMEIRetinoic acid receptor RXR-beta/0.447
1y6bAAXVascular endothelial growth factor receptor 22.7.10.10.447
1ysx4EBSerum albumin/0.447
1zgi382Prothrombin3.4.21.50.447
2bu9HFVIsopenicillin N synthase1.21.3.10.447
2cn0F25Prothrombin3.4.21.50.447
2fk8SAMHydroxymycolate synthase MmaA42.1.10.447
2jfz003Glutamate racemase/0.447
2o2yTCLEnoyl-ACP reductase/0.447
2zi224UProthrombin3.4.21.50.447
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
3dd125DGlycogen phosphorylase, liver form2.4.1.10.447
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
3maaFKPAdenylate cyclase type 2/0.447
3maaFKPAdenylate cyclase type 5/0.447
3qwc98PProthrombin3.4.21.50.447
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
3tamM06Gag-Pol polyprotein2.7.7.490.447
3uibSB2Putative mitogen-activated protein kinase/0.447
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.447
3vmmP0DAlanine--anticapsin ligase/0.447
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.447
3zkyWT4Isopenicillin N synthase1.21.3.10.447
4a81DXCMajor pollen allergen Bet v 1-A/0.447
4c717RD3-oxoacyl-ACP synthase/0.447
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.447
4i13FOLDihydrofolate reductase1.5.1.30.447
4iah1DXAlr2278 protein/0.447
4jsfQJ4Nitric oxide synthase, brain1.14.13.390.447
4l5b1UXDeoxycytidine kinase2.7.1.740.447
4msk2C8Tankyrase-12.4.2.300.447
4n4v2GYTankyrase-12.4.2.300.447
4oeyDHTAndrogen receptor/0.447
4qmuSKESerine/threonine-protein kinase 242.7.11.10.447
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.447
4tjy3GNTankyrase-22.4.2.300.447
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.447
5iqaGNPBifunctional AAC/APH2.3.10.447
1cqp803Integrin alpha-L/0.446
1mueCDDProthrombin3.4.21.50.446
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
1prcUQ1Reaction center protein L chain/0.446
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.446
1s0xC3SNuclear receptor ROR-alpha/0.446
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
1tg56454-hydroxyphenylpyruvate dioxygenase1.13.11.270.446
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.446
1z95198Androgen receptor/0.446
1zprCB3Thymidylate synthase/0.446
2aclL05Oxysterols receptor LXR-alpha/0.446
2amaDHTAndrogen receptor/0.446
2bxqIMNSerum albumin/0.446
2bzgSAHThiopurine S-methyltransferase2.1.1.670.446
2eixFADNADH-cytochrome b5 reductase/0.446
2g0nGDPRas-related C3 botulinum toxin substrate 3/0.446
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.446
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
2jh6894Prothrombin3.4.21.50.446
2olcADPMethylthioribose kinase2.7.1.1000.446
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.446
2rlcCHDCholoylglycine hydrolase3.5.1.240.446
2tohHBITyrosine 3-monooxygenase1.14.16.20.446
2xwyIB8Genome polyprotein2.7.7.480.446
2z2w770Wee1-like protein kinase2.7.10.20.446
2zda32UProthrombin3.4.21.50.446
3b8z294A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.446
3b99U51Prostacyclin synthase/0.446
3di6PDZGag-Pol polyprotein2.7.7.490.446
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.446
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.446
3k47D09Dihydrofolate reductase1.5.1.30.446
3l0lHC3Nuclear receptor ROR-gamma/0.446
3lalKRVGag-Pol polyprotein2.7.7.490.446
3linE13Protease/0.446
3m4nPA9N-acetylornithine carbamoyltransferase2.1.3.90.446
3nr4PYVAbscisic acid receptor PYL2/0.446
3p0pNNFTankyrase-22.4.2.300.446
3q7dNPXProstaglandin G/H synthase 21.14.99.10.446
3r7uX96Cyclin-dependent kinase 22.7.11.220.446
3sfi3SFHTH-type transcriptional regulator EthR/0.446
3tkyN7I(Iso)eugenol O-methyltransferase2.1.1.1460.446
4at2ASDPossible succinate dehydrogenase/0.446
4c61LMMTyrosine-protein kinase JAK2/0.446
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
4ivy1GTEstrogen receptor/0.446
4xg1LLPDiaminopimelate decarboxylase/0.446
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.446
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.446
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.446
1coyANDCholesterol oxidase1.1.3.60.445
1d3dBZTProthrombin3.4.21.50.445
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.445
1hb3SCVIsopenicillin N synthase1.21.3.10.445
1lf2R37Plasmepsin-23.4.23.390.445
1p4mADPRiboflavin kinase2.7.1.260.445
1pq944BOxysterols receptor LXR-beta/0.445
1sr7MOFProgesterone receptor/0.445
1t79DHTAndrogen receptor/0.445
1uh5TCLEnoyl-ACP reductase/0.445
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
2bfmTOPPteridine reductase 11.5.1.330.445
2fhnBNIAvidin-related protein 4/5/0.445
2fziDH3Dihydrofolate reductase1.5.1.30.445
2hw2RFPRifampin ADP-ribosyl transferase/0.445
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.445
2p5uNADUDP-glucose 4-epimerase/0.445
2piuDHTAndrogen receptor/0.445
2pmdGNPTranslation initiation factor 2 subunit gamma/0.445
2pnuENMAndrogen receptor/0.445
2qgtEEDEstrogen receptor/0.445
2r64740Cyclin-dependent kinase 22.7.11.220.445
2w3wVG9Dihydrofolate reductase/0.445
3drpR8EGag-Pol polyprotein2.7.7.490.445
3f03FMNPentaerythritol tetranitrate reductase/0.445
3fznD7KBenzoylformate decarboxylase4.1.1.70.445
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.445
3mdvCL6Cholesterol 24-hydroxylase/0.445
3n5vXFHNitric oxide synthase, brain1.14.13.390.445
3ov4EQUSteroid Delta-isomerase5.3.3.10.445
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.445
3zoiM2WIsopenicillin N synthase1.21.3.10.445
4eomATPCyclin-dependent kinase 22.7.11.220.445
4hxs1A3Bromodomain-containing protein 4/0.445
4jlk1NODeoxycytidine kinase2.7.1.740.445
4ma628EAra h 8 allergen/0.445
4p66MTXDihydrofolate reductase/0.445
4ph9IBPProstaglandin G/H synthase 21.14.99.10.445
4qa1B3NHistone deacetylase 83.5.1.980.445
4rrlA3SProbable threonine--tRNA ligase 26.1.1.30.445
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
4zgsNADPutative D-lactate dehydrogenase/0.445
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.445
5k2dZMAAdenosine receptor A2a/0.445
1cjuFOKAdenylate cyclase type 2/0.444
1cjuFOKAdenylate cyclase type 5/0.444
1crbRTLRetinol-binding protein 1/0.444
1dr4HBIDihydrofolate reductase1.5.1.30.444
1m8h6NINitric oxide synthase, inducible1.14.13.390.444
1qjgEQUSteroid Delta-isomerase5.3.3.10.444
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.444
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.444
1tezHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.444
1u33LM2Pancreatic alpha-amylase/0.444
1uzwCDHIsopenicillin N synthase1.21.3.10.444
1w06W05Isopenicillin N synthase1.21.3.10.444
2eckADPAdenylate kinase/0.444
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.444
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.444
2ofv242Tyrosine-protein kinase Lck2.7.10.20.444
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.444
2vagV25Dual specificity protein kinase CLK12.7.12.10.444
2xlsFADPutative flavin-containing monooxygenase/0.444
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.444
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3dqrJI2Nitric oxide synthase, brain1.14.13.390.444
3h3r14HCollagen type IV alpha-3-binding protein/0.444
3o8gO8GHTH-type transcriptional regulator EthR/0.444
3p67FMNPentaerythritol tetranitrate reductase/0.444
3pn1IVHDNA ligase/0.444
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
3tq8TOPDihydrofolate reductase/0.444
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.444
3wrhCAMCamphor 5-monooxygenase1.14.15.10.444
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.444
4ddrMMVDihydrofolate reductase1.5.1.30.444
4eiyZMAAdenosine receptor A2a/0.444
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4tuvCPZCytochrome P450 1191.140.444
5ansRX87,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.444
5fsxADPUncharacterized protein/0.444
5iqgGDPBifunctional AAC/APH2.3.10.444
1an5CB3Thymidylate synthase/0.443
1aqbRTLRetinol-binding protein 4/0.443
1dajMOTDihydrofolate reductase1.5.1.30.443
1dgbNDPCatalase1.11.1.60.443
1ndzFR5Adenosine deaminase3.5.4.40.443
1olmVTQSEC14-like protein 2/0.443
1s3wTQTDihydrofolate reductase1.5.1.30.443
1uwzTHUCytidine deaminase3.5.4.50.443
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
1y0s331Peroxisome proliferator-activated receptor delta/0.443
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
1zzlTZYMitogen-activated protein kinase 14/0.443
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2j14GNIPeroxisome proliferator-activated receptor delta/0.443
2jh5895Prothrombin3.4.21.50.443
2pixDHTAndrogen receptor/0.443
2wpa889Cyclin-dependent kinase 22.7.11.220.443
2x7gPVBSRSF protein kinase 22.7.11.10.443
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.443
2ylpTESAndrogen receptor/0.443
2zb8IMNProstaglandin reductase 21.3.1.480.443
3gdsVAL_TYR_TYR_PHESerine endoprotease DegS3.4.21.1070.443
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.443
3jw5TOPDihydrofolate reductase/0.443
3mdmFJZCholesterol 24-hydroxylase/0.443
3ndvAICBeta-peptidyl aminopeptidase BapA/0.443
3p6pA6BCamphor 5-monooxygenase1.14.15.10.443
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.443
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.443
3qrtX14Cyclin-dependent kinase 22.7.11.220.443
3r0tFU9Casein kinase II subunit alpha2.7.11.10.443
3rs7GNPGTPase HRas/0.443
3ufqHW5Nitric oxide synthase, brain1.14.13.390.443
3ufrH5WNitric oxide synthase, brain1.14.13.390.443
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.443
3zmmF9JTyrosine-protein kinase JAK2/0.443
4a0sCO8Octenoyl-CoA reductase/carboxylase/0.443
4fgrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.443
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4h9506UDihydrofolate reductase1.5.1.30.443
4hkiFLNTankyrase-22.4.2.300.443
4j0s1H3Bromodomain-containing protein 4/0.443
4k4j1O8Retinoic acid receptor RXR-alpha/0.443
4m8e29VRetinoic acid receptor RXR-alpha/0.443
4nm9FADBifunctional protein PutA/0.443
4r20AERCytochrome P450 family 17 polypeptide 2/0.443
4rr8A3SProbable threonine--tRNA ligase 26.1.1.30.443
5cmx0G6Prothrombin3.4.21.50.443
5d1bTSNHistone deacetylase 83.5.1.980.443
5kgjACOPredicted acetyltransferase/0.443
5g53NECAdenosine receptor A2a/0.443
5iu86DZAdenosine receptor A2a/0.443
1ankANPAdenylate kinase/0.442
1brpRTLRetinol-binding protein 4/0.442
1dhfFOLDihydrofolate reductase1.5.1.30.442
1eqhFLPProstaglandin G/H synthase 11.14.99.10.442
1khrVIRStreptogramin A acetyltransferase2.3.10.442
1kl2FONSerine hydroxymethyltransferase/0.442
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.442
1xj7DHTAndrogen receptor/0.442
1zdwFLVPrenyltransferase/0.442
1zzrDP9Nitric oxide synthase, brain1.14.13.390.442
2ab8MTPAdenosine kinase2.7.1.200.442
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
2hvcLGDAndrogen receptor/0.442
2hvdADPNucleoside diphosphate kinase A2.7.4.60.442
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.442
2tscCB3Thymidylate synthase/0.442
2vcxD26Hematopoietic prostaglandin D synthase/0.442
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.442
2yloTESAndrogen receptor/0.442
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.442
3cseN22Uncharacterized protein/0.442
3d73NBBPheromone-binding protein ASP1/0.442
3d78NBBPheromone-binding protein ASP1/0.442
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3le62BZCyclin-dependent kinase 22.7.11.220.442
3mnrSD1Heat shock protein HSP 90-alpha/0.442
3nj0PYVAbscisic acid receptor PYL2/0.442
3nxoD2BDihydrofolate reductase1.5.1.30.442
3o8hO8HHTH-type transcriptional regulator EthR/0.442
3p62FMNPentaerythritol tetranitrate reductase/0.442
3qlrNDPDihydrofolate reductase1.5.1.30.442
3qxpX64Cyclin-dependent kinase 22.7.11.220.442
3tmz06XCytochrome P450 2B41.14.14.10.442
3tn8F18Cyclin-dependent kinase 92.7.11.220.442
3uwlFOZThymidylate synthase/0.442
4fkpLS5Cyclin-dependent kinase 22.7.11.220.442
4g8zTOPDihydrofolate reductase1.5.1.30.442
4h4m494Gag-Pol polyprotein2.7.7.490.442
4l33F70Tankyrase-22.4.2.300.442
4m7vRARDihydrofolate reductase/0.442
4myq19TcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.442
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.442
4ug71EVNitric oxide synthase oxygenase1.14.13.1650.442
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.442
5ewjQELNMDA glutamate receptor subunit/0.442
5ewjQELGlutamate receptor ionotropic, NMDA 2B/0.442
5fd8A5APutative carboxypeptidase yocD/0.442
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1ia4TQ6Dihydrofolate reductase1.5.1.30.441
1iiuRTLRetinol-binding protein 4/0.441
1mrqSTRAldo-keto reductase family 1 member C1/0.441
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.441
1ot7CHCBile acid receptor/0.441
1ya3STRMineralocorticoid receptor/0.441
1zucT98Progesterone receptor/0.441
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.441
2b7aIZATyrosine-protein kinase JAK2/0.441
2bf7HBIPteridine reductase 11.5.1.330.441
2ejzSAHDiphthine synthase/0.441
2iviACWIsopenicillin N synthase1.21.3.10.441
2ptfFMNUncharacterized protein MTH_863/0.441
2xd6XD6ATP-dependent molecular chaperone HSP82/0.441
2xvfFADPutative flavin-containing monooxygenase/0.441
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.441
3deiRXBCaspase-33.4.22.560.441
3fgoACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.441
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.441
3kr8XAVTankyrase-22.4.2.300.441
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3nj8NJ8Enoyl-acyl carrier reductase/0.441
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
3pxyJWSCyclin-dependent kinase 22.7.11.220.441
3zvuA8SAbscisic acid receptor PYR1/0.441
4a2jAS0Progesterone receptor/0.441
4ap7F47Hepatocyte growth factor receptor2.7.10.10.441
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.441
4erwSTUCyclin-dependent kinase 22.7.11.220.441
4fhd0TTSpore photoproduct lyase/0.441
4gk4L90Ephrin type-A receptor 32.7.10.10.441
4gqkADPActin cross-linking toxin VgrG1/0.441
4j0r1H2Bromodomain-containing protein 4/0.441
4k9nTZDBenzoylformate decarboxylase4.1.1.70.441
4kfj1R0Dihydrofolate reductase1.5.1.30.441
4nfhPFBAlcohol dehydrogenase E chain1.1.1.10.441
4nyiGNPGTPase HRas/0.441
5hs1VORLanosterol 14-alpha demethylase/0.441
5jscFADPutative acyl-CoA dehydrogenase/0.441
5kj1PFBAlcohol dehydrogenase E chain1.1.1.10.441
5kjePFBAlcohol dehydrogenase E chain1.1.1.10.441
1blzACVIsopenicillin N synthase1.21.3.10.440
1cjkFOKAdenylate cyclase type 2/0.440
1cjkFOKAdenylate cyclase type 5/0.440
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1eqgIBPProstaglandin G/H synthase 11.14.99.10.440
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
1q4gBFLProstaglandin G/H synthase 11.14.99.10.440
1tkcM6TTransketolase 12.2.1.10.440
1vzaUMPThymidylate synthase/0.440
1xq3R18Androgen receptor/0.440
1ypeUIPProthrombin3.4.21.50.440
2aazCB3Thymidylate synthase2.1.1.450.440
2bn4FADNADPH--cytochrome P450 reductase/0.440
2ds11CDCyclin-dependent kinase 22.7.11.220.440
2ea1GPGRibonuclease I3.1.27.60.440
2hl0A3SThreonine--tRNA ligase6.1.1.30.440
2opqHBQGag-Pol polyprotein2.7.7.490.440
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.440
2v18FMNDodecin/0.440
2vbpVB1Isopenicillin N synthase1.21.3.10.440
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.440
2x7hPFNProstaglandin reductase 310.440
2ynfWHUGag-Pol polyprotein2.7.7.490.440
3a8wATPProtein kinase C iota type2.7.11.130.440
3c15FOKAdenylate cyclase type 2/0.440
3c15FOKAdenylate cyclase type 5/0.440
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.440
3ielU5PRibonuclease TTHA02523.10.440
3ix4TX1Transcriptional activator protein LasR/0.440
3kdiA8SAbscisic acid receptor PYL2/0.440
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.440
3lfsA07Cyclin-dependent kinase 22.7.11.220.440
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
3ql3FOLDihydrofolate reductase1.5.1.30.440
3rak03ZCyclin-dependent kinase 22.7.11.220.440
3rinI2OMitogen-activated protein kinase 14/0.440
3v94WYQPhosphodiesterase/0.440
3vhuSNLMineralocorticoid receptor/0.440
3w0uHPWLactoylglutathione lyase4.4.1.50.440
4bfyZVYPantothenate kinase2.7.1.330.440
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.440
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4gqiM49Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
4jq7KJQEpidermal growth factor receptor2.7.10.10.440
4lwaQ13Nitric oxide synthase oxygenase1.14.13.1650.440
4mv8ACPBiotin carboxylase6.3.4.140.440
4oilHFTAndrogen receptor/0.440
4okb198Androgen receptor/0.440
5irnADPNucleotide binding oligomerization domain containing 2/0.440
5jr34MUCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.440
3pwhZMAAdenosine receptor A2a/0.440