sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3le9 | 727 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3le9 | 727 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 1.000 | |
| 3l0v | 724 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.742 | |
| 2i47 | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.636 | |
| 3kmc | 403 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.626 | |
| 1zxc | IH6 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.625 | |
| 2i47 | KGY | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.619 | |
| 3kme | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.615 | |
| 3b92 | 440 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.601 | |
| 3l0t | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.572 | |
| 2a8h | 4NH | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.557 | |
| 1zvx | FIN | Neutrophil collagenase | 3.4.24.34 | 0.546 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.545 | |
| 1mnc | PLH | Neutrophil collagenase | 3.4.24.34 | 0.540 | |
| 1biw | S80 | Stromelysin-1 | 3.4.24.17 | 0.535 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.535 | |
| 1bzs | BSI | Neutrophil collagenase | 3.4.24.34 | 0.534 | |
| 1atl | 0QI | Snake venom metalloproteinase atrolysin-D | 3.4.24.42 | 0.532 | |
| 3lgp | 50X | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.529 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.519 | |
| 3e8r | 615 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.519 | |
| 1gkc | NFH | Matrix metalloproteinase-9 | 3.4.24.35 | 0.513 | |
| 4gr8 | R4C | Macrophage metalloelastase | 3.4.24.65 | 0.513 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.512 | |
| 1rm8 | BAT | Matrix metalloproteinase-16 | 3.4.24 | 0.511 | |
| 1g05 | BBH | Stromelysin-1 | 3.4.24.17 | 0.510 | |
| 2wo8 | 077 | Macrophage metalloelastase | 3.4.24.65 | 0.510 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.510 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.509 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.507 | |
| 2woa | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.506 | |
| 1b8y | IN7 | Stromelysin-1 | 3.4.24.17 | 0.502 | |
| 2jih | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | 3.4.24 | 0.502 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.502 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.499 | |
| 1caq | DPS | Stromelysin-1 | 3.4.24.17 | 0.497 | |
| 3kds | NHX | ATP-dependent zinc metalloprotease FtsH | / | 0.497 | |
| 1hv5 | RXP | Stromelysin-3 | 3.4.24 | 0.496 | |
| 1hy7 | MBS | Stromelysin-1 | 3.4.24.17 | 0.496 | |
| 2wo8 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.496 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.496 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.495 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.493 | |
| 2w14 | WR2 | Snake venom metalloproteinase BaP1 | 3.4.24 | 0.493 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.493 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.493 | |
| 3i7g | 732 | Collagenase 3 | 3.4.24 | 0.491 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.490 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.489 | |
| 1zs0 | EIN | Neutrophil collagenase | 3.4.24.34 | 0.489 | |
| 3aig | 0ZC | Snake venom metalloproteinase adamalysin-2 | 3.4.24.46 | 0.489 | |
| 4gr3 | R45 | Macrophage metalloelastase | 3.4.24.65 | 0.489 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.487 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.487 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.486 | |
| 3f28 | S7B | Thermolysin | 3.4.24.27 | 0.486 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.486 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.484 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.484 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.484 | |
| 2w13 | WR2 | Snake venom metalloproteinase BaP1 | 3.4.24 | 0.484 | |
| 2wo9 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.484 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.484 | |
| 2o4c | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.483 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.483 | |
| 2w0d | CGS | Macrophage metalloelastase | 3.4.24.65 | 0.482 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.482 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.481 | |
| 5a3c | NAD | SIR2 family protein | / | 0.481 | |
| 1axw | MTX | Thymidylate synthase | / | 0.480 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.480 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.480 | |
| 4ja1 | NGH | Stromelysin-1 | 3.4.24.17 | 0.480 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.479 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.479 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.479 | |
| 2ovz | 5MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.478 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.478 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.478 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.478 | |
| 5kj1 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.478 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.477 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.477 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.477 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.477 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.477 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.477 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.477 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.477 | |
| 1g4k | HQQ | Stromelysin-1 | 3.4.24.17 | 0.476 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.476 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.476 | |
| 2jnp | NGH | Stromelysin-1 | 3.4.24.17 | 0.476 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.476 | |
| 3ie3 | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.476 | |
| 2e83 | FMN | FMN-binding protein | / | 0.475 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.475 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 1g49 | 111 | Stromelysin-1 | 3.4.24.17 | 0.474 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.474 | |
| 2f3m | GTD | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.474 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.474 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.474 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.473 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.473 | |
| 1sln | INH | Stromelysin-1 | 3.4.24.17 | 0.473 | |
| 2dw0 | GM6 | Zinc metalloproteinase-disintegrin-like VAP2B | 3.4.24 | 0.473 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.473 | |
| 4hxy | NDP | Plm1 | / | 0.473 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.472 | |
| 4r3a | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.472 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.471 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.471 | |
| 2xs3 | ALA_PHE_THR_SER | Karilysin | 3.4.24 | 0.471 | |
| 3beo | UD1 | UDP-N-acetylglucosamine 2-epimerase | / | 0.471 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.471 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.471 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.470 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.470 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.470 | |
| 3f2p | S3B | Thermolysin | 3.4.24.27 | 0.470 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.470 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.470 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.469 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.469 | |
| 1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.469 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.469 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.469 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 4f9c | 0SX | Cell division cycle 7-related protein kinase | 2.7.11.1 | 0.469 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.469 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.468 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.467 | |
| 1odx | 0E8 | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.467 | |
| 2rkg | AB1 | Pol protein | / | 0.467 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.467 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 3qw8 | CYS_ARG_GLY_CYS_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.467 | |
| 3zhb | NAP | Putative dehydrogenase | / | 0.467 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.466 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 1vbn | YSA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.466 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.466 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.466 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 2xs4 | ALA_PHE_THR | Karilysin | 3.4.24 | 0.466 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.466 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.466 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.466 | |
| 4o4f | ATP | Kinase | / | 0.466 | |
| 5cds | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.466 | |
| 1gqt | ACP | Ribokinase | / | 0.465 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.465 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.465 | |
| 2bun | FAD | AppA protein | / | 0.465 | |
| 2e8h | SAH | Diphthine synthase | / | 0.465 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.465 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.465 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.465 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.465 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.465 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.465 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.465 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.465 | |
| 4o4e | ATP | Kinase | / | 0.465 | |
| 4uoc | NCN | CinA-like protein | / | 0.465 | |
| 1lm1 | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.464 | |
| 1p9w | ANP | Type II secretion system protein E | / | 0.464 | |
| 2eva | ADN | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.464 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.464 | |
| 2pzi | AXX | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.464 | |
| 3u9e | COA | Lmo1369 protein | / | 0.464 | |
| 3zmm | F9J | Tyrosine-protein kinase JAK2 | / | 0.464 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.464 | |
| 5cdt | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.464 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.463 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.463 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.463 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.463 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.463 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.463 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.463 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.463 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.463 | |
| 5cdg | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.463 | |
| 1c6y | MK1 | Protease | / | 0.462 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.462 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.462 | |
| 1wng | SAH | Diphthine synthase | / | 0.462 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 2emr | SAH | Diphthine synthase | / | 0.462 | |
| 2owk | SAH | Diphthine synthase | / | 0.462 | |
| 2oxw | ILE_ALA_GLY | Macrophage metalloelastase | 3.4.24.65 | 0.462 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.462 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3i81 | EBI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.462 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.462 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.462 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.462 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.462 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.462 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.462 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.461 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.461 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.461 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.461 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.461 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.461 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.461 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.461 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.461 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.461 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.461 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.461 | |
| 4cje | Q31 | Integrase | / | 0.461 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.461 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.461 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.461 | |
| 4yqf | GDP | Septin-9 | / | 0.461 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.460 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.460 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2c3c | NAP | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.460 | |
| 2dsg | SAH | Diphthine synthase | / | 0.460 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.460 | |
| 2e8q | SAH | Diphthine synthase | / | 0.460 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.460 | |
| 2r8o | T5X | Transketolase 1 | / | 0.460 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.460 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.460 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.460 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 1kor | ANP | Argininosuccinate synthase | / | 0.459 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.459 | |
| 2el0 | SAH | Diphthine synthase | / | 0.459 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.459 | |
| 2ow0 | 6MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.459 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.459 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.459 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.459 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.459 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.459 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4c4o | NAD | SADH | / | 0.459 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.459 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.459 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.459 | |
| 4eub | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.459 | |
| 4k77 | 1Q4 | Tyrosine-protein kinase JAK1 | / | 0.459 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.459 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.459 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.458 | |
| 2ehl | SAH | Diphthine synthase | / | 0.458 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.458 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.458 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.458 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.458 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.458 | |
| 6gsw | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.458 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.457 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.457 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.457 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.457 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.457 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.457 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.457 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.457 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.457 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.457 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.457 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.457 | |
| 3sdi | 3SD | Proteasome subunit beta type-5 | 3.4.25.1 | 0.457 | |
| 3sdi | 3SD | Proteasome subunit beta type-6 | 3.4.25.1 | 0.457 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.457 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.457 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.457 | |
| 4g9l | NGH | Stromelysin-1 | 3.4.24.17 | 0.457 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.457 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.457 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.457 | |
| 1d7x | SPC | Stromelysin-1 | 3.4.24.17 | 0.456 | |
| 1q12 | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.456 | |
| 1zp4 | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.456 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.456 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.456 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.456 | |
| 3a3g | DLZ | Lumazine protein | / | 0.456 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.456 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.456 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.456 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.456 | |
| 3e8x | NAP | BH1520 protein | / | 0.456 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.456 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.456 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.456 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.456 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4k39 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.456 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4wcx | SAM | Biotin and thiamin synthesis associated | / | 0.456 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.456 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.455 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.455 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.455 | |
| 2jsd | NGH | Matrix metalloproteinase-20 | 3.4.24 | 0.455 | |
| 2pch | SAH | Diphthine synthase | / | 0.455 | |
| 2z6r | SAH | Diphthine synthase | / | 0.455 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.455 | |
| 3fst | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.455 | |
| 3kry | 3KR | Collagenase 3 | 3.4.24 | 0.455 | |
| 3oho | Z79 | Stromelysin-1 | 3.4.24.17 | 0.455 | |
| 3w3o | ROE | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.455 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.455 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.455 | |
| 4h57 | 0PJ | Thermolysin | 3.4.24.27 | 0.455 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 5cyo | GDP | Septin-9 | / | 0.455 | |
| 5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.455 | |
| 1bmf | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.454 | |
| 1bmf | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.454 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.454 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.454 | |
| 1jk3 | BAT | Macrophage metalloelastase | 3.4.24.65 | 0.454 | |
| 1l7x | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.454 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.454 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.454 | |
| 2nli | FMN | Lactate oxidase | / | 0.454 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.454 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.454 | |
| 3a3b | RBF | Lumazine protein | / | 0.454 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.454 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.454 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.454 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.454 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.454 | |
| 3ts1 | TYA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.454 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.454 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.454 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.454 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.454 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.454 | |
| 5es7 | FON | Linear gramicidin synthase subunit A | / | 0.454 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.453 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.453 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 1i9c | 5AD | Glutamate mutase epsilon subunit | / | 0.453 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1r2j | FAD | FkbI | / | 0.453 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.453 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.453 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.453 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2e07 | SAH | Diphthine synthase | / | 0.453 | |
| 2ejz | SAH | Diphthine synthase | / | 0.453 | |
| 2fmo | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.453 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.453 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.453 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.453 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.453 | |
| 3b2e | ADP | ATPase GET3 | / | 0.453 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.453 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.453 | |
| 3nbv | ANP | Ketohexokinase | / | 0.453 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.453 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.453 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.453 | |
| 4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.453 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.453 | |
| 4kgn | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.453 | |
| 4mk7 | 28O | Genome polyprotein | 2.7.7.48 | 0.453 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.453 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.453 | |
| 5ej6 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.453 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.453 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.452 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 1vce | SAH | Diphthine synthase | / | 0.452 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2du2 | FMN | Lactate oxidase | / | 0.452 | |
| 2dxx | SAH | Diphthine synthase | / | 0.452 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.452 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.452 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.452 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.452 | |
| 4jic | FMN | GTN Reductase | / | 0.452 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.452 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.452 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.452 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.452 | |
| 1e3l | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.451 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.451 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 1n2i | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.451 | |
| 1ppj | ANY | Cytochrome b | / | 0.451 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.451 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.451 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.451 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.451 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.451 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
| 2p6l | SAH | Diphthine synthase | / | 0.451 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.451 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.451 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 3c89 | ARG_ARG_GLY_MET_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.451 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.451 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.451 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 3zt0 | ZT0 | Integrase | / | 0.451 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.451 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.451 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4oae | CLM | Uncharacterized protein | / | 0.451 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.451 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.451 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 5fkl | TDC | Tetracycline repressor protein class D | / | 0.451 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.451 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.450 | |
| 1dth | BAT | Snake venom metalloproteinase atrolysin-D | 3.4.24.42 | 0.450 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.450 | |
| 1nw6 | SFG | Modification methylase RsrI | 2.1.1.72 | 0.450 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.450 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 1xgj | HTC | Beta-lactamase | 3.5.2.6 | 0.450 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.450 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.450 | |
| 2emu | SAH | Diphthine synthase | / | 0.450 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.450 | |
| 2gn4 | UD1 | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.450 | |
| 2jt2 | C90 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.450 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.450 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.450 | |
| 2ya3 | J7V | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.450 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.450 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.450 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.450 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3ivm | ZPR | Prolyl endopeptidase | / | 0.450 | |
| 3o96 | IQO | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.450 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.450 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.450 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.450 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.450 | |
| 4gap | NAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.450 | |
| 4loc | BTN | Pyruvate carboxylase | / | 0.450 | |
| 4u7w | NDP | MxaA | / | 0.450 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.450 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.450 | |
| 1bqo | N25 | Stromelysin-1 | 3.4.24.17 | 0.449 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.449 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.449 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.449 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.449 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.449 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.449 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.449 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.449 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.449 | |
| 2hut | SAH | Diphthine synthase | / | 0.449 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.449 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.449 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.449 | |
| 2r8p | T6F | Transketolase 1 | / | 0.449 | |
| 2vj6 | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 2yvl | SAM | tRNA (adenine(58)-N(1))-methyltransferase TrmI | / | 0.449 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.449 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 3ieu | GDP | GTPase Era | / | 0.449 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.449 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3tif | ADP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.449 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.449 | |
| 4fv4 | EK7 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4h6p | FMN | Chromate reductase | / | 0.449 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.449 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.449 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.449 | |
| 5a3b | APR | SIR2 family protein | / | 0.449 | |
| 1b3d | S27 | Stromelysin-1 | 3.4.24.17 | 0.448 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.448 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.448 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2aqj | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.448 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.448 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.448 | |
| 2ejk | SAH | Diphthine synthase | / | 0.448 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.448 | |
| 2huv | SAH | Diphthine synthase | / | 0.448 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.448 | |
| 2i51 | FMN | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding | / | 0.448 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2qn7 | HBZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.448 | |
| 2rc3 | NAD | CBS domain | / | 0.448 | |
| 2srt | INH | Stromelysin-1 | 3.4.24.17 | 0.448 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3awh | FMN | FMN-binding protein | / | 0.448 | |
| 3bmo | NAP | Pteridine reductase | / | 0.448 | |
| 3fr8 | NDP | Ketol-acid reductoisomerase, chloroplastic | 1.1.1.86 | 0.448 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.448 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4gu6 | 10N | Focal adhesion kinase 1 | 2.7.10.2 | 0.448 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.448 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.448 | |
| 5hq8 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.448 | |
| 1aa6 | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.447 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.447 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.447 | |
| 1d5j | MM3 | Stromelysin-1 | 3.4.24.17 | 0.447 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 1q3a | NGH | Stromelysin-2 | 3.4.24.22 | 0.447 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.447 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 2bqv | A1A | Protease | / | 0.447 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.447 | |
| 2dxv | SAH | Diphthine synthase | / | 0.447 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.447 | |
| 2en5 | SAH | Diphthine synthase | / | 0.447 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.447 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 2y4g | TIR | TamL | / | 0.447 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.447 | |
| 3fpj | SAM | Uncharacterized protein | / | 0.447 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3mje | NDP | AmphB | / | 0.447 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.447 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.447 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.447 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.446 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.446 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.446 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.446 | |
| 2e8s | SAH | Diphthine synthase | / | 0.446 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.446 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.446 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.446 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.446 | |
| 2ou5 | FMN | Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein | / | 0.446 | |
| 2owu | SAH | Diphthine synthase | / | 0.446 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.446 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.446 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.446 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.446 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.446 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.446 | |
| 3r9i | ADP | Septum site-determining protein MinD | / | 0.446 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.446 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.446 | |
| 4cj3 | E4F | Integrase | / | 0.446 | |
| 4egk | RDC | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.446 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 4j55 | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4lut | DCS | Alanine racemase | / | 0.446 | |
| 5dp2 | NAP | CurF | / | 0.446 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.445 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.445 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.445 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.445 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.445 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.445 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.445 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.445 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.445 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.445 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.445 | |
| 2ejj | SAH | Diphthine synthase | / | 0.445 | |
| 2ji6 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.445 | |
| 2p6i | SAH | Diphthine synthase | / | 0.445 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.445 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.445 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.445 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.445 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.445 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.445 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.445 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.445 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.445 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.445 | |
| 3w1r | MRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.445 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.445 | |
| 3zlx | 5EZ | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.445 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.445 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.445 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.445 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.445 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.445 | |
| 4iva | 1J5 | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.445 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.445 | |
| 4req | 5AD | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.445 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.445 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.445 | |
| 4z87 | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.445 | |
| 1cde | DZF | Phosphoribosylglycinamide formyltransferase | / | 0.444 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.444 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.444 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.444 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.444 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.444 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.444 | |
| 2e17 | SAH | Diphthine synthase | / | 0.444 | |
| 2gbl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.444 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.444 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2vw5 | BC6 | ATP-dependent molecular chaperone HSP82 | / | 0.444 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.444 | |
| 2wtk | ANP | STE20-related kinase adapter protein alpha | / | 0.444 | |
| 3ayk | CGS | Interstitial collagenase | 3.4.24.7 | 0.444 | |
| 3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.444 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 3h3c | P1E | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.444 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.444 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.444 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.444 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.444 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.444 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.444 | |
| 4hr2 | ADP | Nucleoside diphosphate kinase | / | 0.444 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 4q4k | FMN | Uncharacterized protein | / | 0.444 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.444 | |
| 5c48 | URM | Histo-blood group ABO system transferase | / | 0.444 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.443 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.443 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.443 | |
| 1g5q | ASP_SER_TYR_THR_CYS | Epidermin decarboxylase | 4.1.1 | 0.443 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.443 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.443 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.443 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.443 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.443 | |
| 2g8a | UMP | Thymidylate synthase | / | 0.443 | |
| 2p5c | SAH | Diphthine synthase | / | 0.443 | |
| 2p5f | SAH | Diphthine synthase | / | 0.443 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.443 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.443 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.443 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.443 | |
| 3i0a | DBH | Neutrophil gelatinase-associated lipocalin | / | 0.443 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.443 | |
| 3pmu | F7L | Endothiapepsin | 3.4.23.22 | 0.443 | |
| 3qvi | K95 | HAP protein | / | 0.443 | |
| 3rfa | SAM | Dual-specificity RNA methyltransferase RlmN | / | 0.443 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.443 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4abz | T1C | Tetracycline repressor protein class D | / | 0.443 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.443 | |
| 4dxd | 9PC | Cell division protein FtsZ | / | 0.443 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.443 | |
| 4mqy | 2CW | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.443 | |
| 4nif | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 4pzd | NAD | 3-Hydroxyacyl-CoA dehydrogenase | / | 0.443 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.443 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.443 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.443 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.443 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.443 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1d4j | MSC | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.442 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.442 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.442 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.442 | |
| 1nj5 | P5A | Proline--tRNA ligase | / | 0.442 | |
| 1p0y | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.442 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.442 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.442 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.442 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.442 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.442 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.442 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.442 | |
| 2z6j | TUI | 2-nitropropane dioxygenase | / | 0.442 | |
| 3b1j | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.442 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.442 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.442 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.442 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.442 | |
| 3rbq | GLY_ALA_GLY_DAO | Protein unc-119 homolog A | / | 0.442 | |
| 3unj | 0BX | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.442 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.442 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.442 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.442 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.442 | |
| 4gt3 | ATP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.442 | |
| 4id9 | NAD | Putative UDP-glucose 4-epimerase | / | 0.442 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.442 | |
| 4nfh | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 4o1p | ANP | Ribonuclease L | / | 0.442 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.442 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.442 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.441 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 1f4e | TPR | Thymidylate synthase | / | 0.441 | |
| 1gil | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.441 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.441 | |
| 1i6k | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.441 | |
| 1ig1 | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.441 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.441 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1m0b | 0ZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.441 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.441 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1zio | AP5 | Adenylate kinase | / | 0.441 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.441 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.441 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.441 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 2jdv | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.441 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.441 | |
| 3a20 | FMN | FMN-binding protein | / | 0.441 | |
| 3coz | 54H | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.441 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.441 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3t8v | BTJ | M1 family aminopeptidase | 3.4.11 | 0.441 | |
| 3zsw | ZSW | Integrase | / | 0.441 | |
| 4axa | RKD | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 4dja | FAD | (6-4) photolyase | / | 0.441 | |
| 4e2y | JHZ | Methyltransferase | / | 0.441 | |
| 4ebf | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.441 | |
| 4eh9 | 0OQ | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.441 | |
| 4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4hzp | COA | Conserved hypthetical protein | / | 0.441 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.441 | |
| 4wso | NAD | Probable nicotinate-nucleotide adenylyltransferase | / | 0.441 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 4xbo | SAH | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.1.1.200 | 0.441 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.441 | |
| 4z54 | GDP | Neuronal-specific septin-3 | / | 0.441 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.441 | |
| 1bof | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.440 | |
| 1d8f | SPI | Stromelysin-1 | 3.4.24.17 | 0.440 | |
| 1e1x | NW1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.440 | |
| 1q8w | M77 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 1qf2 | TI3 | Thermolysin | 3.4.24.27 | 0.440 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.440 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.440 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.440 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.440 | |
| 2e77 | FMN | Lactate oxidase | / | 0.440 | |
| 2egs | SAH | Diphthine synthase | / | 0.440 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.440 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.440 | |
| 2fze | APR | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.440 | |
| 2iyg | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.440 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.440 | |
| 2npf | MOU | Elongation factor 2 | / | 0.440 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.440 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.440 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.440 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.440 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.440 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.440 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3q1f | YPP | Beta-lactamase | / | 0.440 | |
| 3qtt | ANP | Pantothenate synthetase | / | 0.440 | |
| 3zsr | O3N | Integrase | / | 0.440 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.440 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.440 | |
| 4cez | O3N | Integrase | / | 0.440 | |
| 4ck1 | OM1 | Integrase | / | 0.440 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.440 | |
| 4erk | OLO | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.440 | |
| 4tln | LNO | Thermolysin | 3.4.24.27 | 0.440 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4y9d | NAI | C alpha-dehydrogenase | / | 0.440 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.440 | |
| 5cnn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 |