sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3g0d | XIH | Dipeptidyl peptidase 4 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3g0d | XIH | Dipeptidyl peptidase 4 | / | 1.000 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.810 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.726 | |
| 3ccc | 7AC | Dipeptidyl peptidase 4 | / | 0.702 | |
| 3opm | LUI | Dipeptidyl peptidase 4 | / | 0.670 | |
| 4a5s | N7F | Dipeptidyl peptidase 4 | / | 0.631 | |
| 4g1f | 0WG | Dipeptidyl peptidase 4 | / | 0.570 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.553 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.547 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.546 | |
| 2aj8 | SC3 | Dipeptidyl peptidase 4 | / | 0.536 | |
| 1z44 | FMN | NADPH dehydrogenase | / | 0.512 | |
| 2rgu | 356 | Dipeptidyl peptidase 4 | / | 0.511 | |
| 3fvl | BHK | Carboxypeptidase A1 | 3.4.17.1 | 0.509 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.505 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.504 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.504 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.501 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.498 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.496 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.495 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.495 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.495 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.494 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.493 | |
| 3kej | 3EJ | Collagenase 3 | 3.4.24 | 0.493 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.493 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.492 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.492 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.492 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.490 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.490 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.488 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.487 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.486 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.486 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.486 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.486 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.485 | |
| 2yqz | SAM | Uncharacterized protein | / | 0.485 | |
| 3ivx | FG6 | Pantothenate synthetase | 6.3.2.1 | 0.485 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.484 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.484 | |
| 1i6k | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.483 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.483 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.483 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.483 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.482 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.482 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.481 | |
| 4fdu | IHS | Putative multiple inositol polyphosphate histidine phosphatase 1 | / | 0.481 | |
| 4lut | DCS | Alanine racemase | / | 0.481 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.480 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.480 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.480 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.480 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.480 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.480 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.479 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.479 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.479 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.478 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.478 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.477 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.477 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.477 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.477 | |
| 4zol | GTP | Tubulin alpha-1B chain | / | 0.477 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.476 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.476 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.476 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.475 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.475 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.474 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.474 | |
| 2wca | NP6 | O-GlcNAcase BT_4395 | / | 0.474 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.474 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.474 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.474 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.474 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.473 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.473 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.473 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.473 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.473 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.473 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.472 | |
| 3kt3 | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.472 | |
| 4e31 | JHZ | Methyltransferase | / | 0.472 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.471 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.471 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.471 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.471 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.471 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.471 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.471 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.471 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.471 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.471 | |
| 5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.471 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.470 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.470 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.470 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 4ffw | 715 | Dipeptidyl peptidase 4 | / | 0.470 | |
| 1z48 | FMN | NADPH dehydrogenase | / | 0.469 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.469 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.469 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.469 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.469 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.469 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.469 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.469 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.469 | |
| 4rvd | SAM | D-mycarose 3-C-methyltransferase | / | 0.469 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.469 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.468 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.468 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.468 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.468 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.468 | |
| 4blr | UTP | NTPase P4 | / | 0.468 | |
| 4e32 | DWN | Methyltransferase | / | 0.468 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.468 | |
| 4q23 | RIS | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.468 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.468 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.468 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.467 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.467 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.467 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.467 | |
| 3ukf | GDU | UDP-galactopyranose mutase | / | 0.467 | |
| 4die | C5P | Cytidylate kinase | / | 0.467 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.466 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.466 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.466 | |
| 2q9c | GNP | Signal recognition particle receptor FtsY | / | 0.466 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 3zxi | TYA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.466 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.465 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 2b8v | 3BN | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.465 | |
| 3l67 | FMN | Xenobiotic reductase | / | 0.465 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.465 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 4o4l | GTP | Tubulin alpha-1B chain | / | 0.465 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.464 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.464 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.464 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.464 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.464 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.464 | |
| 3daa | PDD | D-alanine aminotransferase | 2.6.1.21 | 0.464 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.464 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.464 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.464 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.464 | |
| 4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.464 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.464 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.463 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.463 | |
| 2viv | VG2 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.463 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.463 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.463 | |
| 3ivm | ZPR | Prolyl endopeptidase | / | 0.463 | |
| 3w8r | ACP | Uridine kinase | / | 0.463 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.463 | |
| 4tlz | NAP | KtzI | / | 0.463 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.462 | |
| 1p4a | PCP | Pur operon repressor | / | 0.462 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.462 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.462 | |
| 3ndj | JHZ | Methyltransferase | / | 0.462 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.462 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.461 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.461 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.461 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 1z41 | FMN | NADPH dehydrogenase | / | 0.461 | |
| 2dra | ATP | CCA-adding enzyme | 2.7.7.72 | 0.461 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.461 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.461 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.461 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.461 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.461 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.461 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.461 | |
| 4j7h | TRH | PCZA361.3 | / | 0.461 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.460 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.460 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.460 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.460 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.460 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.460 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.460 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.460 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.459 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.459 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.459 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.459 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.459 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.459 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.459 | |
| 3nh8 | DC2 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) | 3.5.1.114 | 0.459 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.459 | |
| 4e2w | JHZ | Methyltransferase | / | 0.459 | |
| 4e2z | JHZ | Methyltransferase | / | 0.459 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.459 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.459 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.459 | |
| 1i6l | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.458 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.458 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.458 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.458 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.458 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.458 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.458 | |
| 4blv | SAM | Ribosomal RNA large subunit methyltransferase J | / | 0.458 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.458 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.458 | |
| 4xd1 | T3Q | Qdtf | / | 0.458 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.458 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.457 | |
| 1nl4 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.457 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.457 | |
| 3kek | 3EK | Collagenase 3 | 3.4.24 | 0.457 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.457 | |
| 3ua8 | 08W | Glutamate receptor 2 | / | 0.457 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.457 | |
| 1cne | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.456 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.456 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 1n0s | FLU | Bilin-binding protein | / | 0.456 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.456 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.456 | |
| 1wkh | PPE | [LysW]-aminoadipate semialdehyde transaminase | / | 0.456 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.456 | |
| 2r8p | T6F | Transketolase 1 | / | 0.456 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.456 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.456 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.456 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.456 | |
| 5c41 | ACP | Ribokinase | / | 0.456 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.456 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.455 | |
| 1dj2 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.455 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.455 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.455 | |
| 2pid | YSA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.455 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.455 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.455 | |
| 3pnd | FAD | FAD:protein FMN transferase | / | 0.455 | |
| 3t70 | DU4 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.455 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.455 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.455 | |
| 4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.455 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.455 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.454 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.454 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.454 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.454 | |
| 2pja | 33Z | Carboxypeptidase B | / | 0.454 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.454 | |
| 4e2d | FMN | Dehydrogenase | / | 0.454 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.454 | |
| 4gv8 | DUP | DUTPase | / | 0.454 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.454 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1zpt | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.453 | |
| 2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.453 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.453 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2jgs | BTN | Avidin | / | 0.453 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.453 | |
| 2oah | QIN | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.453 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.453 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.453 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.453 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.453 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.453 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.453 | |
| 3zxh | E41 | Collagenase 3 | 3.4.24 | 0.453 | |
| 4b0q | GMF | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.453 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.452 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.452 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.452 | |
| 2r5n | TPP | Transketolase 1 | / | 0.452 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.452 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.452 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.452 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.452 | |
| 3c8a | ARG_ARG_GLY_LEU_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.452 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.452 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.452 | |
| 4e2y | JHZ | Methyltransferase | / | 0.452 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.451 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.451 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.451 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.451 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.451 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.451 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2zue | ANP | Arginine--tRNA ligase | 6.1.1.19 | 0.451 | |
| 3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.451 | |
| 3e30 | ED4 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4iv8 | SAM | Phosphoethanolamine N-methyltransferase,putative | / | 0.451 | |
| 4kcf | AKM | FAD-dependent oxidoreductase | / | 0.451 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.451 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.451 | |
| 4tv9 | GTP | Tubulin alpha-1B chain | / | 0.451 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.450 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.450 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.450 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.450 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.450 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.450 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.450 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.450 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.450 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4axa | RKD | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.450 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.450 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.450 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.450 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.450 | |
| 4z54 | GDP | Neuronal-specific septin-3 | / | 0.450 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 1lon | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.449 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.449 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.449 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.449 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.449 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3e6e | DCS | Alanine racemase | / | 0.449 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.449 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 4h12 | SAH | Histone-lysine N-methyltransferase SETD2 | 2.1.1.43 | 0.449 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.449 | |
| 4jb1 | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.449 | |
| 4kc4 | WS3 | Histo-blood group ABO system transferase | / | 0.449 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.449 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 1e1c | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.448 | |
| 1rz1 | NAD | Phenol 2-hydroxylase component B | / | 0.448 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.448 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.448 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.448 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2r8o | T5X | Transketolase 1 | / | 0.448 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.448 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3e8x | NAP | BH1520 protein | / | 0.448 | |
| 3irh | DTP | HD domain protein | / | 0.448 | |
| 3l7g | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.448 | |
| 3vrb | FTN | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.448 | |
| 3vrb | FTN | Cytochrome b-large subunit | / | 0.448 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 3wcz | NAP | Aldo-keto reductase AKR2E4 | / | 0.448 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.448 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.447 | |
| 1p3d | UMA | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.447 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.447 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 2e15 | SAH | Diphthine synthase | / | 0.447 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.447 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.447 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.447 | |
| 2oae | AIL | Dipeptidyl peptidase 4 | / | 0.447 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.447 | |
| 2q3e | NAI | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.447 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.447 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.447 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.447 | |
| 3qdl | FMN | Oxygen-insensitive NADPH nitroreductase | / | 0.447 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.447 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.447 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.447 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.446 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.446 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.446 | |
| 2h8x | FMN | XenA | / | 0.446 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.446 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.446 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.446 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.446 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.446 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.446 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.446 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.446 | |
| 3iex | GMP | Purine nucleoside phosphorylase | / | 0.446 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.446 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.446 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.446 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.446 | |
| 6req | 3CP | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.446 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.445 | |
| 1j21 | ATP | Argininosuccinate synthase | / | 0.445 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 1n2g | APC | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.445 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.445 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3d3x | ARG_ILE_MET_GLU_NH2 | Type E botulinum toxin | / | 0.445 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.445 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.445 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.445 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.445 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.445 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 4rxr | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.445 | |
| 4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.445 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.445 | |
| 5ebu | FMN | Lactate oxidase | / | 0.445 | |
| 1jik | 545 | Tyrosine--tRNA ligase | / | 0.444 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.444 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.444 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.444 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.444 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.444 | |
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.444 | |
| 2fbw | CBE | Succinate dehydrogenase cytochrome b, large subunit | / | 0.444 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.444 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.444 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.444 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.444 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.444 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.444 | |
| 3w1q | YRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.444 | |
| 3zid | GDP | Tubulin-like protein CetZ | / | 0.444 | |
| 3zmg | 6Z0 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.444 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.444 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.444 | |
| 4jic | FMN | GTN Reductase | / | 0.444 | |
| 4oaq | NDP | R-specific carbonyl reductase | / | 0.444 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.443 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.443 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.443 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.443 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.443 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.443 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.443 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2eka | SAH | Diphthine synthase | / | 0.443 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.443 | |
| 3c1o | NAP | Eugenol synthase | / | 0.443 | |
| 3euf | BAU | Uridine phosphorylase 1 | / | 0.443 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.443 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.443 | |
| 3pz4 | 3PZ | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.443 | |
| 3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.443 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.443 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.443 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.443 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.443 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.443 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.443 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.443 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.443 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 1njj | ORX | Ornithine decarboxylase | / | 0.442 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.442 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.442 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.442 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.442 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.442 | |
| 3eks | CY9 | Actin-5C | / | 0.442 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.442 | |
| 3pi5 | 3P5 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.442 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4frj | DWB | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.442 | |
| 4lh7 | 1X8 | DNA ligase | / | 0.442 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.442 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.441 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.441 | |
| 1kev | NDP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.441 | |
| 1kh2 | ATP | Argininosuccinate synthase | / | 0.441 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.441 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.441 | |
| 2bkj | FMN | NADPH-flavin oxidoreductase | / | 0.441 | |
| 2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2h6i | CYS_VAL_LEU_SER_GER | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.441 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.441 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.441 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3c96 | FAD | Flavin-containing monooxygenase | / | 0.441 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.441 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.441 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.441 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.441 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.441 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4b70 | WM9 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 4fx9 | COA | Coenzyme A disulfide reductase | 1.8.1.14 | 0.441 | |
| 4hmv | WUB | Phenazine biosynthesis protein PhzG | 1.4 | 0.441 | |
| 4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.441 | |
| 4xsv | CTP | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.441 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.441 | |
| 5fl3 | ADP | Pili retraction protein PilT | / | 0.441 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.440 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.440 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.440 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.440 | |
| 1ksz | PGS | Adenylosuccinate synthetase | / | 0.440 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.440 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.440 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.440 | |
| 1v5y | 4HC | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.440 | |
| 1xnj | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.440 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.440 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.440 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.440 | |
| 2rgj | FAD | Flavin-containing monooxygenase | / | 0.440 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.440 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.440 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.440 | |
| 3ppo | DCK | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.440 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.440 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4d5g | FAD | Cyclohexane-1,2-dione hydrolase | 3.7.1.11 | 0.440 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.440 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 |