Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
4avu | LDR | Tankyrase-2 | 2.4.2.30 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
4avu | LDR | Tankyrase-2 | 2.4.2.30 | 1.000 | |
4l2g | 1V4 | Tankyrase-2 | 2.4.2.30 | 0.690 | |
4bs4 | A64 | Tankyrase-2 | 2.4.2.30 | 0.684 | |
4hl5 | 15W | Tankyrase-2 | 2.4.2.30 | 0.665 | |
4buw | F33 | Tankyrase-2 | 2.4.2.30 | 0.656 | |
4bue | JQF | Tankyrase-2 | 2.4.2.30 | 0.655 | |
4l0v | 1V1 | Tankyrase-2 | 2.4.2.30 | 0.644 | |
4hlf | 15Z | Tankyrase-2 | 2.4.2.30 | 0.627 | |
4l2k | 1V8 | Tankyrase-2 | 2.4.2.30 | 0.627 | |
4iue | AJ4 | Tankyrase-2 | 2.4.2.30 | 0.624 | |
4hlm | 16S | Tankyrase-2 | 2.4.2.30 | 0.620 | |
4kzl | 20D | Tankyrase-2 | 2.4.2.30 | 0.617 | |
4hmh | F94 | Tankyrase-2 | 2.4.2.30 | 0.612 | |
4j21 | AJ6 | Tankyrase-2 | 2.4.2.30 | 0.609 | |
4bux | F35 | Tankyrase-2 | 2.4.2.30 | 0.608 | |
4l2f | 1V3 | Tankyrase-2 | 2.4.2.30 | 0.605 | |
3p0p | NNF | Tankyrase-2 | 2.4.2.30 | 0.601 | |
4l32 | 1VF | Tankyrase-2 | 2.4.2.30 | 0.600 | |
4bus | 32F | Tankyrase-2 | 2.4.2.30 | 0.594 | |
4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.592 | |
4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.588 | |
4l33 | F70 | Tankyrase-2 | 2.4.2.30 | 0.588 | |
4buv | 16I | Tankyrase-2 | 2.4.2.30 | 0.587 | |
4l0i | 1UW | Tankyrase-2 | 2.4.2.30 | 0.580 | |
4j3l | AJ5 | Tankyrase-2 | 2.4.2.30 | 0.578 | |
4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.573 | |
4avw | G18 | Tankyrase-2 | 2.4.2.30 | 0.571 | |
4hki | FLN | Tankyrase-2 | 2.4.2.30 | 0.565 | |
4krs | 1SX | Tankyrase-1 | 2.4.2.30 | 0.558 | |
3u9y | 09L | Tankyrase-2 | 2.4.2.30 | 0.553 | |
4tkg | 09L | Tankyrase-2 | 2.4.2.30 | 0.552 | |
1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.537 | |
4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.526 | |
3nx2 | FER | Ferulic acid decarboxylase | / | 0.519 | |
4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.516 | |
3eku | CY9 | Actin-5C | / | 0.511 | |
4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.510 | |
4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.507 | |
1dfo | PLG | Serine hydroxymethyltransferase | 2.1.2.1 | 0.505 | |
4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.503 | |
4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.501 | |
2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.499 | |
1d8f | SPI | Stromelysin-1 | 3.4.24.17 | 0.497 | |
1orr | CDP | CDP-paratose 2-epimerase | / | 0.497 | |
2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.497 | |
4msk | 2C8 | Tankyrase-1 | 2.4.2.30 | 0.495 | |
4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.495 | |
2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.494 | |
3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.494 | |
3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.493 | |
1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.492 | |
2eeq | SAH | Diphthine synthase | / | 0.492 | |
3oho | Z79 | Stromelysin-1 | 3.4.24.17 | 0.492 | |
3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.490 | |
4li8 | 1XQ | Tankyrase-1 | 2.4.2.30 | 0.490 | |
2owu | SAH | Diphthine synthase | / | 0.488 | |
3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.488 | |
3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.488 | |
3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.487 | |
3kry | 3KR | Collagenase 3 | 3.4.24 | 0.487 | |
3vri | 1KX | HLA class I histocompatibility antigen, B-57 alpha chain | / | 0.487 | |
1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.485 | |
5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.485 | |
2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.484 | |
4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.484 | |
3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.483 | |
2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.482 | |
1t3z | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.481 | |
2c20 | NAD | UDP-glucose 4-epimerase | / | 0.481 | |
4qzu | RTL | Retinol-binding protein 2 | / | 0.481 | |
1b8y | IN7 | Stromelysin-1 | 3.4.24.17 | 0.479 | |
1caq | DPS | Stromelysin-1 | 3.4.24.17 | 0.479 | |
1m9n | AMZ | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.479 | |
1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.479 | |
2emu | SAH | Diphthine synthase | / | 0.479 | |
2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.479 | |
3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.479 | |
4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.479 | |
4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.479 | |
2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.478 | |
2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.478 | |
2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.478 | |
2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.478 | |
3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.478 | |
4hus | VIR | Virginiamycin A acetyltransferase | 2.3.1 | 0.478 | |
4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.478 | |
4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.478 | |
4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.477 | |
1cqp | 803 | Integrin alpha-L | / | 0.476 | |
1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.476 | |
2dv4 | SAH | Diphthine synthase | / | 0.476 | |
2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.476 | |
4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.476 | |
2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.475 | |
3jpu | TY4 | Transcriptional activator protein LasR | / | 0.475 | |
1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.474 | |
3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.474 | |
3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.474 | |
4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.474 | |
5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.474 | |
1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.473 | |
2bxq | IMN | Serum albumin | / | 0.473 | |
2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.473 | |
3i6r | J5Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.473 | |
4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.473 | |
5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.473 | |
1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.472 | |
1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.472 | |
2d1n | FA4 | Collagenase 3 | 3.4.24 | 0.472 | |
3wyp | BSO | Streptavidin | / | 0.472 | |
1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.471 | |
2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.471 | |
2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.471 | |
2z6r | SAH | Diphthine synthase | / | 0.471 | |
3zxh | E41 | Collagenase 3 | 3.4.24 | 0.471 | |
4ha6 | PXM | Pyridoxine 4-oxidase | / | 0.471 | |
1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.470 | |
4a7b | 3W4 | Collagenase 3 | 3.4.24 | 0.470 | |
4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.470 | |
1sln | INH | Stromelysin-1 | 3.4.24.17 | 0.469 | |
2rge | GNP | GTPase HRas | / | 0.469 | |
2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.469 | |
2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
3ndj | JHZ | Methyltransferase | / | 0.469 | |
3pxy | JWS | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.469 | |
4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.469 | |
4ozt | P1A | Ecdysone receptor, putative | / | 0.469 | |
1txt | CAA | HMG-CoA synthase | / | 0.468 | |
2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.468 | |
3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
4n1g | CEI | Obelin | / | 0.468 | |
2dsi | SAH | Diphthine synthase | / | 0.467 | |
2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.467 | |
3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.467 | |
3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.467 | |
3vhx | GTP | ADP-ribosylation factor 6 | / | 0.467 | |
3x2f | NAI | Adenosylhomocysteinase | / | 0.467 | |
4l4x | NDP | AmphI | / | 0.467 | |
5iu8 | 6DZ | Adenosine receptor A2a | / | 0.467 | |
1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.466 | |
1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
2trs | PLS | Tryptophan synthase beta chain | 4.2.1.20 | 0.466 | |
3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
3w2f | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.466 | |
4jzr | 4JR | Egl nine homolog 1 | / | 0.466 | |
1sep | BIO | Sepiapterin reductase | 1.1.1.153 | 0.465 | |
1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.465 | |
2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.465 | |
2qcx | PF1 | Aminopyrimidine aminohydrolase | / | 0.465 | |
2yig | 5EL | Collagenase 3 | 3.4.24 | 0.465 | |
4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.465 | |
4guy | KLJ | Macrophage metalloelastase | 3.4.24.65 | 0.465 | |
4psb | GA3 | Cytokinin-specific binding protein | / | 0.465 | |
1kqw | RTL | Cellular retinol-binding protein type II | / | 0.464 | |
1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.464 | |
2eka | SAH | Diphthine synthase | / | 0.464 | |
2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.464 | |
2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.464 | |
3lqf | NAD | Galactitol dehydrogenase | / | 0.464 | |
4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.464 | |
5k2b | ZMA | Adenosine receptor A2a | / | 0.464 | |
1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.463 | |
1dd6 | MCI | Metallo-beta-lactamase type 2 | / | 0.463 | |
1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
1ef9 | 2CP | Methylmalonyl-CoA decarboxylase | 4.1.1.41 | 0.463 | |
1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.463 | |
1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.463 | |
1x8l | OXR | Retinol dehydratase | / | 0.463 | |
1ysl | COA | Hydroxymethylglutaryl-CoA synthase | 2.3.3.10 | 0.463 | |
2gvd | FKP | Adenylate cyclase type 2 | / | 0.463 | |
2gvd | FKP | Adenylate cyclase type 5 | / | 0.463 | |
2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.463 | |
2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.463 | |
3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.463 | |
4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.462 | |
2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
2emr | SAH | Diphthine synthase | / | 0.462 | |
2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.462 | |
2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.462 | |
3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.462 | |
3i7i | 518 | Collagenase 3 | 3.4.24 | 0.462 | |
3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
3l3m | A92 | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.462 | |
3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.462 | |
3tqc | ADP | Pantothenate kinase | / | 0.462 | |
4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.462 | |
4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.462 | |
1fw0 | KAI | Glutamate receptor 2 | / | 0.461 | |
1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.461 | |
1pr6 | XYA | Purine nucleoside phosphorylase DeoD-type | / | 0.461 | |
1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.461 | |
2ejk | SAH | Diphthine synthase | / | 0.461 | |
2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.461 | |
2p2x | SAH | Diphthine synthase | / | 0.461 | |
4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
4rel | KMP | Glycosyltransferase | / | 0.461 | |
1d3d | BZT | Prothrombin | 3.4.21.5 | 0.460 | |
1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.460 | |
1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.460 | |
1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.460 | |
2e15 | SAH | Diphthine synthase | / | 0.460 | |
2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.460 | |
3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.460 | |
3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.460 | |
4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
4j7g | TRH | PCZA361.3 | / | 0.460 | |
4l8u | 9AZ | Serum albumin | / | 0.460 | |
4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.460 | |
1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.459 | |
2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.459 | |
3b9l | AZZ | Serum albumin | / | 0.459 | |
3ew2 | BTN | Hypothetical conserved protein | / | 0.459 | |
3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.459 | |
4gd9 | BTN | Streptavidin | / | 0.459 | |
4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.459 | |
4wuc | ANP | DNA gyrase subunit B | / | 0.459 | |
5k2c | ZMA | Adenosine receptor A2a | / | 0.459 | |
1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.458 | |
1ciz | DPS | Stromelysin-1 | 3.4.24.17 | 0.458 | |
1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.458 | |
1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.458 | |
2egl | SAH | Diphthine synthase | / | 0.458 | |
2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
2vnm | CM8 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.458 | |
2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
3arv | SAU | Chitinase A | / | 0.458 | |
3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.458 | |
3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.458 | |
4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.458 | |
4f1y | CNI | Glutamate receptor 3 | / | 0.458 | |
4lh7 | 1X8 | DNA ligase | / | 0.458 | |
4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.458 | |
5uvi | ZMA | Adenosine receptor A2a | / | 0.458 | |
1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
1wdk | ACO | 3-ketoacyl-CoA thiolase | / | 0.457 | |
1wur | 8DG | GTP cyclohydrolase 1 | / | 0.457 | |
1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
2dxv | SAH | Diphthine synthase | / | 0.457 | |
2e07 | SAH | Diphthine synthase | / | 0.457 | |
2e4n | SAH | Diphthine synthase | / | 0.457 | |
2iea | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.457 | |
2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.457 | |
3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
4prv | ADP | DNA gyrase subunit B | / | 0.457 | |
5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.457 | |
6tmn | 0PI | Thermolysin | 3.4.24.27 | 0.457 | |
1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
1zoy | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.456 | |
1zoy | UQ1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.456 | |
2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
2dv7 | SAH | Diphthine synthase | / | 0.456 | |
2eh4 | SAH | Diphthine synthase | / | 0.456 | |
2ejz | SAH | Diphthine synthase | / | 0.456 | |
2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.456 | |
2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.456 | |
2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.456 | |
2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.456 | |
3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.456 | |
3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.456 | |
3rdq | DTB | Streptavidin | / | 0.456 | |
3rs0 | GNP | GTPase HRas | / | 0.456 | |
4cf7 | ADP | Adenylate kinase | / | 0.456 | |
4eqr | COA | Coenzyme A disulfide reductase | / | 0.456 | |
4hxy | NDP | Plm1 | / | 0.456 | |
4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.456 | |
4lpk | GDP | GTPase KRas | / | 0.456 | |
1e2n | RCA | Thymidine kinase | / | 0.455 | |
1mep | BTN | Streptavidin | / | 0.455 | |
1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.455 | |
2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.455 | |
2vd4 | P21 | Bifunctional protein GlmU | / | 0.455 | |
2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.455 | |
3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.455 | |
3uel | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.455 | |
4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.455 | |
4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.455 | |
1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.454 | |
1yhn | GTP | Ras-related protein Rab-7a | / | 0.454 | |
2dxw | SAH | Diphthine synthase | / | 0.454 | |
2e17 | SAH | Diphthine synthase | / | 0.454 | |
2e8h | SAH | Diphthine synthase | / | 0.454 | |
2ek2 | SAH | Diphthine synthase | / | 0.454 | |
2y88 | 2ER | Phosphoribosyl isomerase A | 5.3.1.16 | 0.454 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.454 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.454 | |
3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.454 | |
3vi5 | M4M | Hematopoietic prostaglandin D synthase | / | 0.454 | |
4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.454 | |
4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.454 | |
4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
4gsu | DWZ | L,D-transpeptidase 2 | 2.3.2 | 0.454 | |
4kxj | P34 | Nucleoprotein | / | 0.454 | |
4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.454 | |
1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.453 | |
1rd4 | L08 | Integrin alpha-L | / | 0.453 | |
1s36 | CEI | Obelin | / | 0.453 | |
1wng | SAH | Diphthine synthase | / | 0.453 | |
1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.453 | |
1xur | PB5 | Collagenase 3 | 3.4.24 | 0.453 | |
1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.453 | |
2d81 | RB3 | Poly(3-hydroxybutyrate) depolymerase | / | 0.453 | |
2eni | SAH | Diphthine synthase | / | 0.453 | |
2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.453 | |
2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.453 | |
2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.453 | |
3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
3fpj | SAM | Uncharacterized protein | / | 0.453 | |
4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.453 | |
4ceq | QCH | Integrase | / | 0.453 | |
4dne | DTB | Streptavidin | / | 0.453 | |
4imf | SI3 | N-acetylneuraminate lyase | / | 0.453 | |
5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.453 | |
5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.453 | |
1gqy | ACP | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.452 | |
1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
1lrm | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.452 | |
1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.452 | |
1y52 | BTN | Avidin-related protein 4/5 | / | 0.452 | |
1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.452 | |
2dsh | SAH | Diphthine synthase | / | 0.452 | |
2dv5 | SAH | Diphthine synthase | / | 0.452 | |
2p9d | SAH | Diphthine synthase | / | 0.452 | |
2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.452 | |
2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.452 | |
2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.452 | |
3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.452 | |
3eks | CY9 | Actin-5C | / | 0.452 | |
3gwd | FAD | Cyclohexanone monooxygenase | / | 0.452 | |
3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.452 | |
3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.452 | |
4an4 | DUD | Putative glycosyl transferase | / | 0.452 | |
4ggz | BTN | Bll1558 protein | / | 0.452 | |
4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.452 | |
4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
4u15 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.452 | |
4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.452 | |
1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
1eio | GCH | Gastrotropin | / | 0.451 | |
1f5f | DHT | Sex hormone-binding globulin | / | 0.451 | |
1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.451 | |
1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.451 | |
1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.451 | |
1trg | CB3 | Thymidylate synthase | / | 0.451 | |
1xjq | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.451 | |
2d1o | FA4 | Stromelysin-1 | 3.4.24.17 | 0.451 | |
2eh5 | SAH | Diphthine synthase | / | 0.451 | |
2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.451 | |
2el3 | SAH | Diphthine synthase | / | 0.451 | |
2woa | 576 | Macrophage metalloelastase | 3.4.24.65 | 0.451 | |
2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
3atz | FMN | Prostaglandin F2a synthase | / | 0.451 | |
3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.451 | |
3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.451 | |
4agd | B49 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.451 | |
4hfp | 15U | Prothrombin | 3.4.21.5 | 0.451 | |
4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.451 | |
5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.451 | |
1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.450 | |
2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.450 | |
2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.450 | |
2e7r | SAH | Diphthine synthase | / | 0.450 | |
2egs | SAH | Diphthine synthase | / | 0.450 | |
2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
2iby | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.450 | |
2ol4 | JPN | Enoyl-ACP reductase | / | 0.450 | |
2pnu | ENM | Androgen receptor | / | 0.450 | |
2xvw | 9NR | Serum albumin | / | 0.450 | |
2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.450 | |
2zl9 | VDA | Vitamin D3 receptor | / | 0.450 | |
3a0t | ADP | Sensor histidine kinase | / | 0.450 | |
3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
3q33 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.450 | |
3q7f | ED2 | Uncharacterized protein | / | 0.450 | |
3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.450 | |
3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.450 | |
4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.450 | |
4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.450 | |
3eml | ZMA | Adenosine receptor A2a | / | 0.450 | |
1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.449 | |
1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
1u30 | GOX | Pancreatic alpha-amylase | / | 0.449 | |
1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
1wl4 | COA | Acetyl-CoA acetyltransferase, cytosolic | 2.3.1.9 | 0.449 | |
2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.449 | |
2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.449 | |
2dsg | SAH | Diphthine synthase | / | 0.449 | |
2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.449 | |
2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.449 | |
2hvd | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.449 | |
2izl | IMI | Streptavidin | / | 0.449 | |
2rgx | AP5 | Adenylate kinase | / | 0.449 | |
2vig | COS | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.449 | |
2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.449 | |
3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
3fvq | ATP | Fe(3+) ions import ATP-binding protein FbpC | / | 0.449 | |
3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.449 | |
3ixp | 834 | Ecdysone receptor | / | 0.449 | |
3ksl | SZH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.449 | |
3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
3utu | 1TS | Prothrombin | 3.4.21.5 | 0.449 | |
4avl | TMP | Polymerase acidic protein | / | 0.449 | |
4bcs | BTN | Avidin-related protein 4/5 | / | 0.449 | |
4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.449 | |
4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.449 | |
4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.449 | |
4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.449 | |
1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
1eii | RTL | Retinol-binding protein 2 | / | 0.448 | |
1g05 | BBH | Stromelysin-1 | 3.4.24.17 | 0.448 | |
1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
1nsy | ATP | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.448 | |
1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.448 | |
1u33 | LM2 | Pancreatic alpha-amylase | / | 0.448 | |
1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.448 | |
1w7i | ADP | Unconventional myosin-Va | / | 0.448 | |
1xxj | UNC | Uricase | 1.7.3.3 | 0.448 | |
2eld | SAH | Diphthine synthase | / | 0.448 | |
2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.448 | |
2hut | SAH | Diphthine synthase | / | 0.448 | |
2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
2j7p | GNP | Signal recognition particle protein | / | 0.448 | |
2j7p | GNP | Signal recognition particle receptor FtsY | / | 0.448 | |
2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.448 | |
2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
2p6l | SAH | Diphthine synthase | / | 0.448 | |
2xtn | GTP | GTPase IMAP family member 2 | / | 0.448 | |
2yy7 | NAD | L-threonine dehydrogenase | / | 0.448 | |
3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.448 | |
3djf | BC3 | Purine nucleoside phosphorylase | / | 0.448 | |
3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
3fx4 | FX4 | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.448 | |
3in6 | FMN | Uncharacterized protein | / | 0.448 | |
3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.448 | |
4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.448 | |
5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.448 | |
1c5n | ESI | Prothrombin | 3.4.21.5 | 0.447 | |
1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.447 | |
1p0y | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.447 | |
1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.447 | |
2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
3amf | FMN | FMN-binding protein | / | 0.447 | |
3b1d | PLS | BetaC-S lyase | / | 0.447 | |
3bv3 | P39 | Mitogen-activated protein kinase 14 | / | 0.447 | |
3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.447 | |
3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
3oqf | S51 | Renin | 3.4.23.15 | 0.447 | |
3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.447 | |
3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.447 | |
3u2m | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.447 | |
4dmg | SAM | Uncharacterized protein | / | 0.447 | |
4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.447 | |
4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.447 | |
4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.447 | |
4nu0 | AP5 | Adenylate kinase | / | 0.447 | |
4qxa | GTP | Ras-related protein Rab-9A | / | 0.447 | |
1b3d | S27 | Stromelysin-1 | 3.4.24.17 | 0.446 | |
1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.446 | |
2p5c | SAH | Diphthine synthase | / | 0.446 | |
2zit | NAD | Exotoxin A | 2.4.2.36 | 0.446 | |
2zw5 | COA | Bleomycin acetyltransferase | / | 0.446 | |
3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.446 | |
3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.446 | |
3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
3ebi | BEY | M1 family aminopeptidase | 3.4.11 | 0.446 | |
3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.446 | |
4bix | ADP | Sensor histidine kinase CpxA | / | 0.446 | |
4eqs | COA | Coenzyme A disulfide reductase | / | 0.446 | |
4f3g | KAI | Glutamate receptor 3 | / | 0.446 | |
4gdp | FAD | Polyamine oxidase FMS1 | / | 0.446 | |
4pyo | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.446 | |
1d8m | BBH | Stromelysin-1 | 3.4.24.17 | 0.445 | |
1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
1o2g | 696 | Prothrombin | 3.4.21.5 | 0.445 | |
1qf4 | RPD | Adenylosuccinate synthetase | / | 0.445 | |
1t91 | GTP | Ras-related protein Rab-7a | / | 0.445 | |
1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.445 | |
1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.445 | |
1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
1xgi | NST | Beta-lactamase | 3.5.2.6 | 0.445 | |
2bjh | FER | Feruloyl esterase A | 3.1.1.73 | 0.445 | |
2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.445 | |
2fb3 | 5AD | GTP 3',8-cyclase | 4.1.99.18 | 0.445 | |
2fyp | RDE | Endoplasmin | / | 0.445 | |
2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.445 | |
2pbz | ATP | Uncharacterized protein | / | 0.445 | |
2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.445 | |
2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
2wn6 | NDP | ADP-ribosyltransferase enzymatic component | / | 0.445 | |
3awh | FMN | FMN-binding protein | / | 0.445 | |
3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.445 | |
3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.445 | |
4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.445 | |
4b4w | 9L9 | Bifunctional protein FolD | / | 0.445 | |
4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.445 | |
4eqw | COA | Coenzyme A disulfide reductase | / | 0.445 | |
4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.445 | |
4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.445 | |
4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.445 | |
4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.445 | |
4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.445 | |
5fm6 | ADP | RuvB-like helicase | / | 0.445 | |
5k2a | ZMA | Adenosine receptor A2a | / | 0.445 | |
1guy | NAD | Malate dehydrogenase | / | 0.444 | |
1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
1khr | VIR | Streptogramin A acetyltransferase | 2.3.1 | 0.444 | |
1kol | NAD | Glutathione-independent formaldehyde dehydrogenase | / | 0.444 | |
1l0o | ADP | Anti-sigma F factor | / | 0.444 | |
1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.444 | |
2gtb | AZP | Orf1ab polyprotein | / | 0.444 | |
2ozr | GG1 | Collagenase 3 | 3.4.24 | 0.444 | |
2pb4 | SAH | Diphthine synthase | / | 0.444 | |
2r8o | T5X | Transketolase 1 | / | 0.444 | |
2rgc | GNP | GTPase HRas | / | 0.444 | |
2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.444 | |
2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.444 | |
2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.444 | |
2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
3dme | FAD | Putative conserved exported protein | / | 0.444 | |
3elm | 24F | Collagenase 3 | 3.4.24 | 0.444 | |
3fpz | AHZ | Thiamine thiazole synthase | / | 0.444 | |
3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
4j49 | 1J1 | Uncharacterized protein | / | 0.444 | |
4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
5hyn | SAH | Histone-lysine N-methyltransferase EZH2 | 2.1.1.43 | 0.444 | |
1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.443 | |
1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.443 | |
1j8u | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.443 | |
1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.443 | |
2c9b | PUG | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.443 | |
2ek4 | SAH | Diphthine synthase | / | 0.443 | |
2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
2pcm | SAH | Diphthine synthase | / | 0.443 | |
2q3f | GNP | Ras-related GTP-binding protein D | / | 0.443 | |
3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.443 | |
3kn0 | 3TO | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
3qtv | 06P | Prothrombin | 3.4.21.5 | 0.443 | |
3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.443 | |
3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.443 | |
3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.443 | |
3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.443 | |
4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.443 | |
4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
4mv3 | ACP | Biotin carboxylase | 6.3.4.14 | 0.443 | |
4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.443 | |
4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.443 | |
4okw | 198 | Androgen receptor | / | 0.443 | |
4uth | FMN | Xenobiotic reductase | / | 0.443 | |
4v01 | 0LI | Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b | / | 0.443 | |
4xvy | SAH | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.443 | |
4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.443 | |
5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.443 | |
1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
1cjt | FOK | Adenylate cyclase type 2 | / | 0.442 | |
1cjt | FOK | Adenylate cyclase type 5 | / | 0.442 | |
1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.442 | |
1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.442 | |
1lke | DOG | Bilin-binding protein | / | 0.442 | |
1mlz | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.442 | |
1mxf | MTX | Putative pteridine reductase 2 | / | 0.442 | |
1nce | CB3 | Thymidylate synthase | / | 0.442 | |
1ur5 | NAD | Malate dehydrogenase | / | 0.442 | |
1w35 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
1x31 | FMN | Subunit alpha of sarocosine oxidase | / | 0.442 | |
1x31 | FMN | Subunit beta of sarcosine oxidase | / | 0.442 | |
1xdd | AAY | Integrin alpha-L | / | 0.442 | |
1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.442 | |
2ed3 | SAH | Diphthine synthase | / | 0.442 | |
2lfo | GCH | Fatty acid-binding protein, liver | / | 0.442 | |
2nli | FMN | Lactate oxidase | / | 0.442 | |
2rtg | BTN | Streptavidin | / | 0.442 | |
2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.442 | |
3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.442 | |
3c1o | NAP | Eugenol synthase | / | 0.442 | |
3c27 | DKK | Prothrombin | 3.4.21.5 | 0.442 | |
3t3i | GPW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.442 | |
3t8v | BTJ | M1 family aminopeptidase | 3.4.11 | 0.442 | |
4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.442 | |
4bak | M67 | Prothrombin | 3.4.21.5 | 0.442 | |
4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.442 | |
4jau | ADP | Sensor histidine kinase | / | 0.442 | |
4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.442 | |
4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.442 | |
4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.442 | |
4tmn | 0PK | Thermolysin | 3.4.24.27 | 0.442 | |
4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.442 | |
5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.442 | |
1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.441 | |
1jmh | UMP | Thymidylate synthase | / | 0.441 | |
1mdt | APU | Diphtheria toxin | / | 0.441 | |
1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
1s9d | AFB | Cytohesin-2 | / | 0.441 | |
1s9d | AFB | ADP-ribosylation factor 1 | / | 0.441 | |
1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
1u2y | GOX | Pancreatic alpha-amylase | / | 0.441 | |
1vce | SAH | Diphthine synthase | / | 0.441 | |
1xud | PB4 | Collagenase 3 | 3.4.24 | 0.441 | |
1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
1y4s | ADP | Chaperone protein HtpG | / | 0.441 | |
2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
2avi | BTN | Avidin | / | 0.441 | |
2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
2gpj | FAD | Siderophore-interacting protein | / | 0.441 | |
2huv | SAH | Diphthine synthase | / | 0.441 | |
2izh | BTN | Streptavidin | / | 0.441 | |
2j62 | GSZ | O-GlcNAcase NagJ | / | 0.441 | |
2jl1 | NAP | Triphenylmethane reductase | / | 0.441 | |
2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.441 | |
2pca | SAH | Diphthine synthase | / | 0.441 | |
3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.441 | |
3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.441 | |
3g1o | RF1 | HTH-type transcriptional regulator EthR | / | 0.441 | |
3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.441 | |
4ajb | TAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.441 | |
4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
4cfa | WOP | Integrase | / | 0.441 | |
4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.441 | |
4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.441 | |
5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.440 | |
1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.440 | |
1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.440 | |
1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.440 | |
1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.440 | |
2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.440 | |
2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.440 | |
2ed5 | SAH | Diphthine synthase | / | 0.440 | |
2ejj | SAH | Diphthine synthase | / | 0.440 | |
2fhn | BNI | Avidin-related protein 4/5 | / | 0.440 | |
2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
2owk | SAH | Diphthine synthase | / | 0.440 | |
2r0p | K2C | Putative FAD-monooxygenase | / | 0.440 | |
2r9x | WH6 | Beta-lactamase | 3.5.2.6 | 0.440 | |
2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.440 | |
2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
2wge | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.440 | |
2x9d | ITC | Tetracycline repressor protein class D | / | 0.440 | |
2y05 | NAP | Prostaglandin reductase 1 | / | 0.440 | |
3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.440 | |
3co9 | 3MS | Genome polyprotein | 2.7.7.48 | 0.440 | |
3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
3f8w | ADN | Purine nucleoside phosphorylase | / | 0.440 | |
3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.440 | |
3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.440 | |
3pi0 | F91 | Endothiapepsin | 3.4.23.22 | 0.440 | |
3rk1 | ATP | N-type ATP pyrophosphatase superfamily | / | 0.440 | |
3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
3rpe | FAD | Putative modulator of drug activity | / | 0.440 | |
3upt | TPP | Transketolase | / | 0.440 | |
3vqx | BLK | Pyrrolysine--tRNA ligase | / | 0.440 | |
4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
4l0t | 1V0 | Tankyrase-2 | 2.4.2.30 | 0.440 | |
4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.440 | |
4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.440 | |
5c3a | URM | Histo-blood group ABO system transferase | / | 0.440 | |
5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.440 | |
3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.440 |