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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4hjoAQ4Epidermal growth factor receptor2.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4hjoAQ4Epidermal growth factor receptor2.7.10.11.000
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.576
1m17AQ4Epidermal growth factor receptor2.7.10.10.575
4jq8KJ8Epidermal growth factor receptor2.7.10.10.569
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.569
4riyADPEpidermal growth factor receptor2.7.10.10.564
4i22IREEpidermal growth factor receptor2.7.10.10.563
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.562
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.560
3vryB43Tyrosine-protein kinase HCK2.7.10.20.557
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.555
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.554
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.550
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.547
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.546
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.545
2itnANPEpidermal growth factor receptor2.7.10.10.543
3w33W19Epidermal growth factor receptor2.7.10.10.543
1xkkFMMEpidermal growth factor receptor2.7.10.10.541
1bygSTUTyrosine-protein kinase CSK/0.539
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.539
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.537
4i231C9Epidermal growth factor receptor2.7.10.10.537
3w32W32Epidermal growth factor receptor2.7.10.10.536
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.534
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.533
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.533
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.531
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.530
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.530
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.528
3vs3VSETyrosine-protein kinase HCK2.7.10.20.528
4jr3KJREpidermal growth factor receptor2.7.10.10.523
2hk51BMTyrosine-protein kinase HCK2.7.10.20.522
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.521
2gs7ANPEpidermal growth factor receptor2.7.10.10.521
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.520
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.519
3poz03PEpidermal growth factor receptor2.7.10.10.518
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.517
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.517
2of2547Tyrosine-protein kinase Lck2.7.10.20.516
4jq7KJQEpidermal growth factor receptor2.7.10.10.515
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.514
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.514
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.514
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.514
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.513
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.513
2itpAEEEpidermal growth factor receptor2.7.10.10.512
2yn8STUEphrin type-B receptor 42.7.10.10.512
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.512
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.509
2wouZZFTGF-beta receptor type-12.7.11.300.509
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.509
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.508
1rw8580TGF-beta receptor type-12.7.11.300.507
3uvqFS8Mitogen-activated protein kinase 14/0.506
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.505
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.505
3vs1VSATyrosine-protein kinase HCK2.7.10.20.505
4wkqIREEpidermal growth factor receptor2.7.10.10.505
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.503
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.503
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.503
4gk2L66Ephrin type-A receptor 32.7.10.10.502
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.501
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.501
4yuqKS1Calmodulin-like domain protein kinase/0.501
1vjy460TGF-beta receptor type-12.7.11.300.500
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.499
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.499
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.499
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.498
3vjoANPEpidermal growth factor receptor2.7.10.10.498
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.498
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.497
4id71G0Activated CDC42 kinase 1/0.497
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.497
1y0s331Peroxisome proliferator-activated receptor delta/0.496
4gk3L87Ephrin type-A receptor 32.7.10.10.496
2ituITQEpidermal growth factor receptor2.7.10.10.494
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.494
2wotZZGTGF-beta receptor type-12.7.11.300.494
5e8wSTUTGF-beta receptor type-12.7.11.300.494
2ittAEEEpidermal growth factor receptor2.7.10.10.493
2itzIREEpidermal growth factor receptor2.7.10.10.493
4ih8B43Calmodulin-domain protein kinase 1/0.493
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.493
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.492
2vwx7X4Ephrin type-B receptor 42.7.10.10.491
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.491
4bb3KKAIsopenicillin N synthase1.21.3.10.491
5k2bZMAAdenosine receptor A2a/0.491
1fm4DXCMajor pollen allergen Bet v 1-L/0.490
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.490
2balPQAMitogen-activated protein kinase 14/0.490
3h86AP5Adenylate kinase/0.490
4i6gFADCryptochrome-2/0.490
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.490
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.490
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.490
1jpaANPEphrin type-B receptor 22.7.10.10.489
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.489
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.489
1yb5NAPQuinone oxidoreductase1.6.5.50.488
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.488
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.487
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.487
1p0hACOMycothiol acetyltransferase2.3.1.1890.486
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.486
3hmm855TGF-beta receptor type-12.7.11.300.486
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.486
1mp0NADAlcohol dehydrogenase class-31.1.1.10.485
1uzwCDHIsopenicillin N synthase1.21.3.10.485
2itvANPEpidermal growth factor receptor2.7.10.10.484
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.484
3gubGUBDeath-associated protein kinase 12.7.11.10.484
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.484
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.483
1xddAAYIntegrin alpha-L/0.483
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.483
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.483
1cqp803Integrin alpha-L/0.482
4btkDTQTau-tubulin kinase 12.7.11.10.482
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.482
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.481
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.481
3to6LYS_CMCHistone acetyltransferase ESA1/0.481
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.480
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.480
2xyuQ9GEphrin type-A receptor 42.7.10.10.479
4eiyZMAAdenosine receptor A2a/0.479
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.479
4lgh0JNProto-oncogene tyrosine-protein kinase Src2.7.10.20.479
4nxvGDPMitochondrial dynamics protein MID51/0.479
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.479
1gqtACPRibokinase/0.478
1h74AGSHomoserine kinase2.7.1.390.478
2vx07X7Ephrin type-B receptor 42.7.10.10.478
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.478
2znnS44Peroxisome proliferator-activated receptor alpha/0.478
3ac2KSETyrosine-protein kinase Lck2.7.10.20.478
3gxlQIGTGF-beta receptor type-12.7.11.300.478
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.478
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.478
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.478
4dpwAGSMevalonate diphosphate decarboxylase/0.478
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.478
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.478
1bxoPP7Penicillopepsin-13.4.23.200.477
1i8tFADUDP-galactopyranose mutase5.4.99.90.477
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.477
1u4dDBQActivated CDC42 kinase 1/0.477
1u8fNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.477
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.477
2ebaFADPutative glutaryl-CoA dehydrogenase/0.477
3b70NAPEnoyl reductase LovC10.477
3q43D66M1 family aminopeptidase3.4.110.477
4bb432WEphrin type-B receptor 42.7.10.10.477
2ahrNAPPyrroline-5-carboxylate reductase/0.476
2hcdBIVVitamin D3 receptor A/0.476
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.476
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.476
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.476
4kiq1RAMitogen-activated protein kinase 14/0.476
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.475
2c475IDCasein kinase I isoform gamma-2/0.475
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.475
2eb3ANPEpidermal growth factor receptor2.7.10.10.475
2xp2VGHALK tyrosine kinase receptor2.7.10.10.475
3gc9B45Mitogen-activated protein kinase 112.7.11.240.475
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.475
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.475
5jtbZMAAdenosine receptor A2a/0.475
2of4979Tyrosine-protein kinase Lck2.7.10.20.474
2po7CHDFerrochelatase, mitochondrial4.99.1.10.474
2q5g1FAPeroxisome proliferator-activated receptor delta/0.474
2qo9ANPEphrin type-A receptor 32.7.10.10.474
2xx91NFGlutamate receptor 2/0.474
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.474
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.474
4fv9E71Mitogen-activated protein kinase 12.7.11.240.474
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.473
2hog710Serine/threonine-protein kinase Chk12.7.11.10.473
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.473
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.473
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.473
3ac1KZITyrosine-protein kinase Lck2.7.10.20.473
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.473
4c02TAKActivin receptor type-12.7.11.300.473
4c62XWWTyrosine-protein kinase JAK2/0.473
4kba1QMCasein kinase I isoform delta2.7.11.10.473
1u54ACPActivated CDC42 kinase 1/0.472
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.472
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.472
4h1m0YJProtein-tyrosine kinase 2-beta2.7.10.20.472
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.472
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.472
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.471
2g226IGRenin3.4.23.150.471
2gtnLIEMitogen-activated protein kinase 14/0.471
2itwITQEpidermal growth factor receptor2.7.10.10.471
2jb4A14Isopenicillin N synthase1.21.3.10.471
3d84NDPDihydrofolate reductase1.5.1.30.471
3r9dX6BCyclin-dependent kinase 22.7.11.220.471
3syiFADSulfide-quinone reductase/0.471
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.471
3w2rW2REpidermal growth factor receptor2.7.10.10.471
4jrvKJVEpidermal growth factor receptor2.7.10.10.471
5br4NADLactaldehyde reductase1.1.1.770.471
1c6yMK1Protease/0.470
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.470
2x3nFADProbable FAD-dependent monooxygenase/0.470
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.470
3fln3FNMitogen-activated protein kinase 14/0.470
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.470
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.470
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.470
4ejmNAPPutative zinc-binding dehydrogenase/0.470
4lj6ACPChaperone protein ClpB/0.470
5kjeNAJAlcohol dehydrogenase E chain1.1.1.10.470
5k2cZMAAdenosine receptor A2a/0.470
2fhnBNIAvidin-related protein 4/5/0.469
2g1r3IGRenin3.4.23.150.469
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.469
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.469
3gbuATPUncharacterized sugar kinase PH14592.7.10.469
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.469
3oqfS51Renin3.4.23.150.469
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.469
3t14FADSulfide-quinone reductase/0.469
4dxd9PCCell division protein FtsZ/0.469
4nka2K7Fibroblast growth factor receptor 1/0.469
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.469
5k2aZMAAdenosine receptor A2a/0.469
1hvyD16Thymidylate synthase2.1.1.450.468
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.468
2vwy7X5Ephrin type-B receptor 42.7.10.10.468
2y0mACOHistone acetyltransferase KAT8/0.468
3aoxEMHALK tyrosine kinase receptor2.7.10.10.468
3ruqADPChaperonin/0.468
3sdi3SDProteasome subunit beta type-53.4.25.10.468
3sdi3SDProteasome subunit beta type-63.4.25.10.468
3w0iO11Vitamin D3 receptor/0.468
4b99R4LMitogen-activated protein kinase 72.7.11.240.468
4jqh1MFAlr2278 protein/0.468
5e8xSTUTGF-beta receptor type-12.7.11.300.468
1nqaNADGlyceraldehyde-3-phosphate dehydrogenase/0.467
1py5PY1TGF-beta receptor type-12.7.11.300.467
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.467
2vx17X8Ephrin type-B receptor 42.7.10.10.467
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.467
3ggfGVDSerine/threonine-protein kinase 26/0.467
3oqkS52Renin3.4.23.150.467
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
3t2zFADSulfide-quinone reductase/0.467
3w18N13Aurora kinase A2.7.11.10.467
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.467
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.467
4wsqKSAAP2-associated protein kinase 12.7.11.10.467
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.467
1fxsNAPGDP-L-fucose synthase/0.466
1yqxNAPSinapyl alcohol dehydrogenase/0.466
2jn3JN3Fatty acid-binding protein, liver/0.466
2pmoHMDProtein kinase 7/0.466
2qoqANPEphrin type-A receptor 32.7.10.10.466
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.466
3kpkFADSulfide-quinone reductase/0.466
3nbvANPKetohexokinase/0.466
3oibFDAPutative acyl-CoA dehydrogenase/0.466
5a3cNADSIR2 family protein/0.466
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
2hziJINTyrosine-protein kinase ABL12.7.10.20.465
2vbdV10Isopenicillin N synthase1.21.3.10.465
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.465
3cukFADD-amino-acid oxidase1.4.3.30.465
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.465
3l8p0CEAngiopoietin-1 receptor2.7.10.10.465
4ez8DHFThymidylate synthase2.1.1.450.465
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.465
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.465
2obyNAPQuinone oxidoreductase PIG310.464
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.464
2xvdAS6Ephrin type-B receptor 42.7.10.10.464
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.464
3mvm39PMitogen-activated protein kinase 14/0.464
4aa4QC0Mitogen-activated protein kinase 14/0.464
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
4g7gVFVLanosterol 14-alpha-demethylase/0.464
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.464
4xgiNADGlutamate dehydrogenase/0.464
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.464
1blzACVIsopenicillin N synthase1.21.3.10.463
1bwsNDPGDP-L-fucose synthase/0.463
1nboNADGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.463
1ppm0P1Penicillopepsin-13.4.23.200.463
2c27ACOMycothiol acetyltransferase2.3.1.1890.463
2j3iNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.463
2j3kNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.463
3cic316Beta-secretase 13.4.23.460.463
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3lvfNADGlyceraldehyde-3-phosphate dehydrogenase 1/0.463
3qa2XNAKetohexokinase/0.463
3t2yFADSulfide-quinone reductase/0.463
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.463
4a6bQG8Gag-Pol polyprotein3.4.23.160.463
4dxhNAJAlcohol dehydrogenase E chain1.1.1.10.463
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.463
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.463
4i02CMPcAMP-activated global transcriptional regulator CRP/0.463
4kb81QNCasein kinase I isoform delta2.7.11.10.463
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.463
4q72FADBifunctional protein PutA/0.463
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.462
1zmdNAIDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.462
2ejvNADL-threonine 3-dehydrogenase/0.462
2fzwNADAlcohol dehydrogenase class-31.1.1.10.462
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.462
2rc3NADCBS domain/0.462
3ds6A17Mitogen-activated protein kinase 14/0.462
3g0eB49Mast/stem cell growth factor receptor Kit2.7.10.10.462
3qlrNDPDihydrofolate reductase1.5.1.30.462
3t2kFADSulfide-quinone reductase/0.462
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.462
4g2fC07Ephrin type-A receptor 32.7.10.10.462
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.462
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
1eh4IC1Casein kinase I homolog 12.7.11.10.461
2excJNKMitogen-activated protein kinase 102.7.11.240.461
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.461
2iviACWIsopenicillin N synthase1.21.3.10.461
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.461
2y6o1N1Ephrin type-A receptor 42.7.10.10.461
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.461
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.461
3gw9VNILanosterol 14-alpha-demethylase/0.461
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.461
4a6cQG9Gag-Pol polyprotein3.4.23.160.461
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.461
5eccNAPDehydrofolate reductase type I/0.461
1nzdUPGDNA beta-glucosyltransferase/0.460
1qorNDPQuinone oxidoreductase 1/0.460
1rneC60Renin3.4.23.150.460
1sguMK1Gag-Pol polyprotein3.4.23.160.460
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.460
2dfvNADL-threonine 3-dehydrogenase/0.460
2j7t274Serine/threonine-protein kinase 102.7.11.10.460
2pmdGNPTranslation initiation factor 2 subunit gamma/0.460
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2rg6287Mitogen-activated protein kinase 14/0.460
2vrx447Aurora kinase B-A2.7.11.10.460
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.460
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.460
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.460
3s4qNK0Mitogen-activated protein kinase 14/0.460
4a84DXCMajor pollen allergen Bet v 1-A/0.460
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.460
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.460
4j5j478Gag-Pol polyprotein3.4.23.160.460
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.460
4nxwADPMitochondrial dynamics protein MID51/0.460
4qe6JN3Bile acid receptor/0.460
5kjcNAJAlcohol dehydrogenase E chain1.1.1.10.460
1hncGDNGlutathione S-transferase Mu 22.5.1.180.459
1k6pXN3Gag-Pol polyprotein3.4.23.160.459
1mj9COAHistone acetyltransferase ESA1/0.459
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.459
1qjfACSIsopenicillin N synthase1.21.3.10.459
2bpw1INGag-Pol polyprotein3.4.23.160.459
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.459
2vwz7X6Ephrin type-B receptor 42.7.10.10.459
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.459
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.459
2xa4AZ5Tyrosine-protein kinase JAK2/0.459
2xgs44PUncharacterized protein/0.459
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.459
3jynNDPQuinone oxidoreductase/0.459
3q3cNADNAD-dependent L-serine dehydrogenase/0.459
3qaiXNNKetohexokinase/0.459
3tucFPWTyrosine-protein kinase SYK2.7.10.20.459
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.459
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.459
3zkyWT4Isopenicillin N synthase1.21.3.10.459
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.459
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.459
4kip1R9Mitogen-activated protein kinase 14/0.459
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.459
4nks2M2Fibroblast growth factor receptor 1/0.459
4yryFADGlutamate synthase, beta subunit/0.459
5br7FADUDP-galactopyranose mutase/0.459
5iu86DZAdenosine receptor A2a/0.459
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.458
1lluNADAlcohol dehydrogenase/0.458
1m78NDPDihydrofolate reductase1.5.1.30.458
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.458
2b8l5HABeta-secretase 13.4.23.460.458
2bu9HFVIsopenicillin N synthase1.21.3.10.458
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.458
2i4qUA4Renin3.4.23.150.458
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.458
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.458
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.458
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.458
2y05NAPProstaglandin reductase 1/0.458
3pm9FADPutative oxidoreductase/0.458
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.458
4ansVGHALK tyrosine kinase receptor2.7.10.10.458
4b7dQLECytochrome P450 monooxygenase PikC/0.458
4b7xNAPProbable oxidoreductase/0.458
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.458
4fnzNZFALK tyrosine kinase receptor2.7.10.10.458
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.458
1bk0ACVIsopenicillin N synthase1.21.3.10.457
1kkq471Peroxisome proliferator-activated receptor alpha/0.457
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.457
2c6o4SPCyclin-dependent kinase 22.7.11.220.457
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
2cig1DGDihydrofolate reductase1.5.1.30.457
2d4vNADIsocitrate dehydrogenase [NADP]/0.457
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.457
2gjlFMNNitronate monooxygenase1.13.12.160.457
2r0cFADPutative FAD-monooxygenase/0.457
2uxoTACHTH-type transcriptional regulator TtgR/0.457
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.457
3k9vCPS1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial/0.457
3oq6NAJAlcohol dehydrogenase E chain1.1.1.10.457
3qlsNDPDihydrofolate reductase1.5.1.30.457
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.457
4l9kEHFSerum albumin/0.457
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.457
4y93746Tyrosine-protein kinase/0.457
5kczNAJAlcohol dehydrogenase E chain1.1.1.10.457
1heuNADAlcohol dehydrogenase E chain1.1.1.10.456
1wuuANPGalactokinase2.7.1.60.456
2dteNAIGlucose 1-dehydrogenase related protein/0.456
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.456
2h3wCOACarnitine O-acetyltransferase2.3.1.70.456
2iko7IGRenin3.4.23.150.456
2nmtNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.456
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.456
2vn0TDZCytochrome P450 2C8/0.456
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.456
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.456
3fhyATPPyridoxal kinase2.7.1.350.456
3hjaNADGlyceraldehyde-3-phosphate dehydrogenase/0.456
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.456
4anqVGHALK tyrosine kinase receptor2.7.10.10.456
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4dieC5PCytidylate kinase/0.456
4jia1K3Tyrosine-protein kinase JAK2/0.456
4q71FADBifunctional protein PutA/0.456
4qgiROCGag-Pol polyprotein3.4.23.160.456
5aaaVGHALK tyrosine kinase receptor2.7.10.10.456
1oc1ASVIsopenicillin N synthase1.21.3.10.455
1qiqACCIsopenicillin N synthase1.21.3.10.455
1rfvADPPyridoxal kinase2.7.1.350.455
1rrmAPRLactaldehyde reductase1.1.1.770.455
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.455
2yutNAPPutative short-chain oxidoreductase/0.455
3bpzCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2/0.455
3d7kD7KBenzaldehyde lyase/0.455
3e2sFADBifunctional protein PutA1.5.5.20.455
3efwAK8Aurora kinase A2.7.11.10.455
3hv5R24Mitogen-activated protein kinase 14/0.455
3js2VM1Fibroblast growth factor receptor 1/0.455
3sjzGNPTranslation initiation factor 2 subunit gamma/0.455
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
4fdnFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.455
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.455
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.455
4j33FADKynurenine 3-monooxygenase/0.455
4lopSB4Mitogen-activated protein kinase 14/0.455
5j3wFMNSensory box protein/0.455
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.455
1bxsNADRetinal dehydrogenase 11.2.1.360.454
1e3eNAIAlcohol dehydrogenase 41.1.1.10.454
1iyzNDPProbable quinone oxidoreductase/0.454
1kzjCB3Thymidylate synthase/0.454
1npvL27Gag-Pol polyprotein3.4.23.160.454
1psa0ZLPepsin A3.4.23.10.454
1s60COAAminoglycoside N(6')-acetyltransferase type 1/0.454
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
2bl4NADLactaldehyde reductase1.1.1.770.454
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.454
2givACOHistone acetyltransferase KAT8/0.454
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.454
2ozuACOHistone acetyltransferase KAT6A/0.454
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.454
3b6zCO7Enoyl reductase LovC10.454
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.454
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.454
3i0pNADMalate dehydrogenase, putative/0.454
3lpkZ76Beta-secretase 13.4.23.460.454
3lu8IQXSerum albumin/0.454
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.454
4g3jVNTLanosterol 14-alpha-demethylase/0.454
4k2xFADPolyketide oxygenase/hydroxylase/0.454
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.454
4ly91YYGlucokinase regulatory protein/0.454
4q73FADBifunctional protein PutA/0.454
4yagNAIC alpha-dehydrogenase/0.454
5dozNDPJamJ/0.454
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.453
1k6cMK1Gag-Pol polyprotein3.4.23.160.453
1me6IVSPlasmepsin-23.4.23.390.453
1nvtNAPShikimate dehydrogenase (NADP(+))/0.453
1qvrANPChaperone protein ClpB/0.453
1reoFADL-amino-acid oxidase1.4.3.20.453
1xkdNAPIsocitrate dehydrogenase [NADP]/0.453
2aa0MTPAdenosine kinase2.7.1.200.453
2bi4NADLactaldehyde reductase1.1.1.770.453
2itqITQEpidermal growth factor receptor2.7.10.10.453
2j14GNIPeroxisome proliferator-activated receptor delta/0.453
2q61SF1Peroxisome proliferator-activated receptor gamma/0.453
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.453
2xrwANPMitogen-activated protein kinase 82.7.11.240.453
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.453
3g70A5TRenin3.4.23.150.453
3hazFADBifunctional protein PutA/0.453
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.453
3q44D50M1 family aminopeptidase3.4.110.453
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.453
3uyt0CKCasein kinase I isoform delta2.7.11.10.453
3vt7VDXVitamin D3 receptor/0.453
3vtdTKDVitamin D3 receptor/0.453
4at0FADPossible succinate dehydrogenase/0.453
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.453
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.453
4nxuADPMitochondrial dynamics protein MID51/0.453
4o8aFADBifunctional protein PutA1.2.1.880.453
4wudANPDNA gyrase subunit B/0.453
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.453
4xiwAZMCarbonic anhydrase, alpha type/0.453
4y8wSTRSteroid 21-hydroxylase/0.453
1bil0IURenin3.4.23.150.452
1fm9570Peroxisome proliferator-activated receptor gamma/0.452
1hb3SCVIsopenicillin N synthase1.21.3.10.452
1j4jACOAcetyltransferase2.3.10.452
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1zemNADXylitol dehydrogenase/0.452
2ev9NAPShikimate dehydrogenase (NADP(+))/0.452
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.452
2ou2ACOHistone acetyltransferase KAT5/0.452
2oz6CMPCyclic AMP receptor-like protein/0.452
3cifNADGlyceraldehyde-3-phosphate dehydrogenase/0.452
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.452
3g0fB49Mast/stem cell growth factor receptor Kit2.7.10.10.452
3gqvNAPEnoyl reductase LovC10.452
3il1B5DGlutamate receptor 2/0.452
3oom507Activin receptor type-12.7.11.300.452
3slkNDPPolyketide synthase extender module 2/0.452
3vrvYSDVitamin D3 receptor/0.452
3zoiM2WIsopenicillin N synthase1.21.3.10.452
4aa5NQBMitogen-activated protein kinase 14/0.452
4euaCOASuccinyl-CoA:acetate CoA-transferase/0.452
4kl9NDPDihydrofolate reductase1.5.1.30.452
4tuvCPZCytochrome P450 1191.140.452
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
5iu4ZMAAdenosine receptor A2a/0.452
1adfTADAlcohol dehydrogenase E chain1.1.1.10.451
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.451
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1k6tXN1Gag-Pol polyprotein3.4.23.160.451
1likADNAdenosine kinase2.7.1.200.451
1nptNADGlyceraldehyde-3-phosphate dehydrogenase/0.451
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2bb9AKCGag-Pol polyprotein3.4.23.160.451
2g20L1ARenin3.4.23.150.451
2npaMMBPeroxisome proliferator-activated receptor alpha/0.451
2pwcG3GGag-Pol polyprotein3.4.23.160.451
2yfxVGHALK tyrosine kinase receptor2.7.10.10.451
3cid318Beta-secretase 13.4.23.460.451
3cwkREACellular retinoic acid-binding protein 2/0.451
3eksCY9Actin-5C/0.451
3k5uPFQAurora kinase A2.7.11.10.451
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.451
3ttjJBIMitogen-activated protein kinase 102.7.11.240.451
3umsGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.451
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.451
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.451
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.451
1bv7XV6Gag-Pol polyprotein3.4.23.160.450
1di9MSQMitogen-activated protein kinase 14/0.450
1me7RVPInosine-5'-monophosphate dehydrogenase/0.450
1mjbACOHistone acetyltransferase ESA1/0.450
1rm5NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.450
1wc4APCAdenylate cyclase/0.450
1xl5190Gag-Pol polyprotein3.4.23.160.450
2a94AP0L-lactate dehydrogenase1.1.1.270.450
2c6eHPMAurora kinase A2.7.11.10.450
2q4wFADCytokinin dehydrogenase 71.5.99.120.450
2vojNADAlanine dehydrogenase1.4.1.10.450
3fql79ZGenome polyprotein2.7.7.480.450
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.450
3o9aK14Pol polyprotein/0.450
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.450
3tvuB37Acetyl-CoA carboxylase/0.450
3uylTYDProbable NDP-rhamnosyltransferase/0.450
4eb4D16Thymidylate synthase2.1.1.450.450
4fod0UVALK tyrosine kinase receptor2.7.10.10.450
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.450
4hgt15GCasein kinase I isoform delta2.7.11.10.450
4iarERM5-hydroxytryptamine receptor 1B/0.450
4nfsNAJAlcohol dehydrogenase E chain1.1.1.10.450
4zohFADPutative oxidoreductase FAD-binding subunit/0.450
5dp2NAPCurF/0.450
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
1llzFMNFerredoxin-dependent glutamate synthase 21.4.7.10.449
1xe55FEPlasmepsin-23.4.23.390.449
1zdwFLVPrenyltransferase/0.449
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2g247IGRenin3.4.23.150.449
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.449
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.449
3e5rNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.449
3hx4ANPCalmodulin-domain protein kinase 1/0.449
3lpiZ74Beta-secretase 13.4.23.460.449
3ocgOCGMitogen-activated protein kinase 14/0.449
3ocpCMPcGMP-dependent protein kinase 12.7.11.120.449
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.449
3w2sW2REpidermal growth factor receptor2.7.10.10.449
3w78CBDFMN-dependent NADH-azoreductase/0.449
4ambDUDPutative glycosyl transferase/0.449
4ckjADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.449
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.449
4r20AERCytochrome P450 family 17 polypeptide 2/0.449
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.449
4xumIMNPeroxisome proliferator-activated receptor gamma/0.449
5ijzNAPNADP-specific glutamate dehydrogenase1.4.1.40.449
1adcPADAlcohol dehydrogenase E chain1.1.1.10.448
1fm6BRLPeroxisome proliferator-activated receptor gamma/0.448
1hw5CMPcAMP-activated global transcriptional regulator CRP/0.448
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1j39UPGDNA beta-glucosyltransferase/0.448
1kzkJE2Gag-Pol polyprotein3.4.23.160.448
1mjaCOAHistone acetyltransferase ESA1/0.448
1nhhANPDNA mismatch repair protein MutL/0.448
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.448
1rfuADPPyridoxal kinase2.7.1.350.448
1txiTX5Vitamin D3 receptor/0.448
1ysx4EBSerum albumin/0.448
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.448
2bhpNAD1-pyrroline-5-carboxylate dehydrogenase/0.448
2c12FADNitroalkane oxidase1.7.3.10.448
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.448
2dvlFADAcyl-CoA dehydrogenase/0.448
2ft9CHDFatty acid-binding protein 2, liver/0.448
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.448
2ikuLIYRenin3.4.23.150.448
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.448
2p83MR0Beta-secretase 13.4.23.460.448
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.448
2rcyNAPPyrroline-5-carboxylate reductase/0.448
2wedPP6Penicillopepsin-13.4.23.200.448
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.448
3i7eDJRGag-Pol polyprotein/0.448
3kvxFMYMitogen-activated protein kinase 102.7.11.240.448
3qwbNDPProbable quinone oxidoreductase1.6.5.50.448
3r374CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.448
3rf7NADIron-containing alcohol dehydrogenase/0.448
3sz0FADSulfide-quinone reductase/0.448
3vucHHERenin3.4.23.150.448
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
4a0mNADBetaine aldehyde dehydrogenase, chloroplastic1.2.1.80.448
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.448
4aotGW8Serine/threonine-protein kinase 102.7.11.10.448
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.448
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.448
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4uymVOR14-alpha sterol demethylase Cyp51B/0.448
5k2dZMAAdenosine receptor A2a/0.448
1aq1STUCyclin-dependent kinase 22.7.11.220.447
1i6xCMPcAMP-activated global transcriptional regulator CRP/0.447
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.447
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.447
1yonA2R2-dehydropantoate 2-reductase1.1.1.1690.447
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.447
2b9wFADPutative aminooxidase/0.447
2c29NAPDihydroflavonol 4-reductase/0.447
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.447
2hamC33Vitamin D3 receptor/0.447
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
2q7vFADThioredoxin reductase/0.447
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
2wecPP5Penicillopepsin-13.4.23.200.447
2y60M8FIsopenicillin N synthase1.21.3.10.447
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.447
2zb3NDPProstaglandin reductase 21.3.1.480.447
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.447
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.447
3fklFKLMitogen-activated protein kinase 14/0.447
3nxxNDPDihydrofolate reductase1.5.1.30.447
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.447
3vt9YI4Vitamin D3 receptor/0.447
3w8wFADPutative FAD-dependent oxygenase EncM/0.447
3zuyTCHTransporter/0.447
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.447
4a99FADTetX family tetracycline inactivation enzyme/0.447
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.447
4fv7E94Mitogen-activated protein kinase 12.7.11.240.447
4g160VMCasein kinase I isoform gamma-32.7.11.10.447
4h3qANPMitogen-activated protein kinase 12.7.11.240.447
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4l06NAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.447
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
1e3lNADAlcohol dehydrogenase 41.1.1.10.446
1efpFADElectron transfer flavoprotein subunit alpha/0.446
1k6vXN2Gag-Pol polyprotein3.4.23.160.446
1pjkANPCasein kinase II subunit alpha2.7.11.10.446
1vdcFADThioredoxin reductase 1, mitochondrial1.8.1.90.446
1w06W05Isopenicillin N synthase1.21.3.10.446
2v16C47Renin3.4.23.150.446
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.446
3aw9NADNAD-dependent epimerase/dehydratase/0.446
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.446
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.446
3gu83GUDeath-associated protein kinase 12.7.11.10.446
3iaeD7KBenzaldehyde lyase/0.446
3kybFADUDP-galactopyranose mutase5.4.99.90.446
3nu6478Gag-Pol polyprotein3.4.23.160.446
3own3OWRenin3.4.23.150.446
4b4w9L9Bifunctional protein FolD/0.446
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
4elf35IDihydrofolate reductase/0.446
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4j31FADKynurenine 3-monooxygenase/0.446
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.446
3emlZMAAdenosine receptor A2a/0.446
1f8fNADBenzyl alcohol dehydrogenase/0.445
1gd1NADGlyceraldehyde-3-phosphate dehydrogenase/0.445
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.445
1ot7IU5Bile acid receptor/0.445
1qvnFRIInterleukin-2/0.445
1xq6NAPUncharacterized protein At5g02240/0.445
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.445
2bxoOPBSerum albumin/0.445
2ca0PXICytochrome P450 monooxygenase PikC/0.445
2dr3ADPUPF0273 protein PH0284/0.445
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.445
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.445
2vwu7X1Ephrin type-B receptor 42.7.10.10.445
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.445
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.445
3a1l2CCCytochrome P450/0.445
3bbrBHYGlutamate receptor 2/0.445
3cgcCOACoenzyme A disulfide reductase/0.445
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
3hk1B64Fatty acid-binding protein, adipocyte/0.445
3iodA6DPantothenate synthetase6.3.2.10.445
3iupNDPPossible NADH oxidoreductase/0.445
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.445
3mkhFADNitroalkane oxidase/0.445
3ol5SAWCamphor 5-monooxygenase1.14.15.10.445
3p62FMNPentaerythritol tetranitrate reductase/0.445
3r4b74TGag-Pol polyprotein/0.445
3sa9A68Protease/0.445
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.445
3vetADPnebramycin 5' synthase6.1.2.20.445
3w0hW12Vitamin D3 receptor/0.445
3wmxNADNAD dependent epimerase/dehydratase/0.445
4a61ANPPlasmid segregation protein ParM/0.445
4aqkADPInositol-pentakisphosphate 2-kinase2.7.1.1580.445
4dpuAGSMevalonate diphosphate decarboxylase/0.445
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4fc7NAPPeroxisomal 2,4-dienoyl-CoA reductase1.3.1.340.445
4h6rFDAProline dehydrogenase/0.445
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.445
4i3wNADAldehyde dehydrogenase (NAD+)/0.445
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.445
4jbiNDPAlcohol dehydrogenase (Zinc)/0.445
4kcfAKMFAD-dependent oxidoreductase/0.445
4l4xNDPAmphI/0.445
4qi5FADCellobiose dehydrogenase/0.445
4qi7FADCellobiose dehydrogenase/0.445
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.445
5jscFADPutative acyl-CoA dehydrogenase/0.445
5uviZMAAdenosine receptor A2a/0.445
1fy7COAHistone acetyltransferase ESA1/0.444
1ia1NDPDihydrofolate reductase1.5.1.30.444
1qbrXV6Gag-Pol polyprotein3.4.23.160.444
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.444
1zrzBI1Protein kinase C iota type2.7.11.130.444
2b7aIZATyrosine-protein kinase JAK2/0.444
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.444
2j0j4STFocal adhesion kinase 12.7.10.20.444
2j9lATPH(+)/Cl(-) exchange transporter 5/0.444
2o0uC0MMitogen-activated protein kinase 102.7.11.240.444
2w2lNADD-mandelate dehydrogenase/0.444
3cr0809Wee1-like protein kinase2.7.10.20.444
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.444
3gfbNADL-threonine 3-dehydrogenase/0.444
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.444
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.444
3mtfA3FActivin receptor type-12.7.11.300.444
3nr4PYVAbscisic acid receptor PYL2/0.444
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.444
3vob9PCCell division protein FtsZ/0.444
3vyfVYFRenin3.4.23.150.444
3wv9FEGHmd co-occurring protein HcgE/0.444
4b5pACOAlpha-tubulin N-acetyltransferase 1/0.444
4b7sQLECytochrome P450 monooxygenase PikC/0.444
4fc00T2Serine/threonine-protein kinase B-raf2.7.11.10.444
4fob0USALK tyrosine kinase receptor2.7.10.10.444
4gk4L90Ephrin type-A receptor 32.7.10.10.444
4hbnCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.444
4l04NAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.444
4l2iFADElectron transfer flavoprotein alpha/beta-subunit/0.444
4loqSB4Mitogen-activated protein kinase 14/0.444
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.444
4wucANPDNA gyrase subunit B/0.444
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.444
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.444
5jlaNADPutative short-chain dehydrogenase/reductase/0.444
4k5y1Q5Corticotropin-releasing factor receptor 1/0.444
1agwSU2Fibroblast growth factor receptor 1/0.443
1bv9XV6Gag-Pol polyprotein3.4.23.160.443
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.443
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.443
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1t2dNADL-lactate dehydrogenase1.1.1.270.443
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
2b1pAIZMitogen-activated protein kinase 102.7.11.240.443
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.443
2cduFADNADH oxidase/0.443
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
2d4eNAD5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenaseiheyensis HTE831]/0.443
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.443
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.443
2r43G3GGag-Pol polyprotein3.4.23.160.443
2wleCOAPolysialic acid O-acetyltransferase/0.443
3a7rLAQLipoate-protein ligase A6.3.1.200.443
3cib314Beta-secretase 13.4.23.460.443
3fmkFMKMitogen-activated protein kinase 14/0.443
3h0aD30Peroxisome proliferator-activated receptor gamma/0.443
3rusADPChaperonin/0.443
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.443
4a6nFADTetX family tetracycline inactivation enzyme/0.443
4c58824Cyclin-G-associated kinase2.7.11.10.443
4c59FEFCyclin-G-associated kinase2.7.11.10.443
4dymIYZActivin receptor type-12.7.11.300.443
4er6AW2Histone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.443
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.443
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.443
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.443
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.443
4ocvANPAminoglycoside phosphotransferase/0.443
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4oztP1AEcdysone receptor, putative/0.443
4uirFADOleate hydratase4.2.1.530.443
4wlvNADMalate dehydrogenase, mitochondrial1.1.1.370.443
4z24FADPutative GMC-type oxidoreductase R13510.443
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.443
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.443
5ejaTD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.443
1g4tFTPThiamine-phosphate synthase/0.442
1ie3NADMalate dehydrogenase/0.442
1iepSTITyrosine-protein kinase ABL12.7.10.20.442
1ma0NADAlcohol dehydrogenase class-31.1.1.10.442
1msmJE2Gag-Pol polyprotein3.4.23.160.442
1phhFADp-hydroxybenzoate hydroxylase/0.442
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.442
1qrpHH0Pepsin A-43.4.23.10.442
1s19MC9Vitamin D3 receptor/0.442
1yp3ATPGlucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic2.7.7.270.442
2cen4AHProtease/0.442
2om9AJAPeroxisome proliferator-activated receptor gamma/0.442
2vbpVB1Isopenicillin N synthase1.21.3.10.442
2vcmM11Isopenicillin N synthase1.21.3.10.442
3gstGPRGlutathione S-transferase Mu 12.5.1.180.442
3hdyFADUDP-galactopyranose mutase/0.442
3imgBZ2Pantothenate synthetase6.3.2.10.442
3kq7KQ7Mitogen-activated protein kinase 14/0.442
3mnrSD1Heat shock protein HSP 90-alpha/0.442
3p8z36AGenome polyprotein2.1.1.560.442
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.442
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.442
3zewSTUEphrin type-B receptor 42.7.10.10.442
4c57FEFCyclin-G-associated kinase2.7.11.10.442
4cf8V7HIntegrase/0.442
4do30LAFatty-acid amide hydrolase 13.5.1.990.442
4e8wIHAD-beta-D-heptose 7-phosphate kinase/0.442
4eh60ONMitogen-activated protein kinase 14/0.442
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4ia3BIVVitamin D3 receptor A/0.442
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.442
4lxhC1EAlpha/beta hydrolase fold/0.442
4nmdFDABifunctional protein PutA/0.442
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.442
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
5aacVGHALK tyrosine kinase receptor2.7.10.10.442
5f0a1FBcGMP-dependent protein kinase, putative/0.442
1cf3FADGlucose oxidase1.1.3.40.441
1e7qNAPGDP-L-fucose synthase/0.441
1hb1OCVIsopenicillin N synthase1.21.3.10.441
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.441
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.441
1ps9FAD2,4-dienoyl-CoA reductase1.3.1.340.441
1tj2FADBifunctional protein PutA1.5.5.20.441
1w2xRCPAcetyl-CoA carboxylase/0.441
1zyjBI5Mitogen-activated protein kinase 14/0.441
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.441
2h96893Mitogen-activated protein kinase 82.7.11.240.441
2lfoGCHFatty acid-binding protein, liver/0.441
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.441
2xynVX6Abelson tyrosine-protein kinase 22.7.10.20.441
2zlcVDXVitamin D3 receptor/0.441
3ekv478Gag-Pol polyprotein3.4.23.160.441
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.441
3nbwTR4Ketohexokinase/0.441
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.441
3q92XNBKetohexokinase/0.441
3uceNDPDehydrogenase/0.441
3vqsJT1Genome polyprotein/0.441
3vydVYDRenin3.4.23.150.441
3w5p4OAVitamin D3 receptor/0.441
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.441
4f3xNADPutative aldehyde dehydrogenase/0.441
4fyo0VFTyrosine-protein kinase SYK2.7.10.20.441
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.441
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4i1wNAD2-aminomuconate 6-semialdehyde dehydrogenase/0.441
4ia7BIVVitamin D3 receptor A/0.441
4iaq2GM5-hydroxytryptamine receptor 1B/0.441
4jq9FADDihydrolipoyl dehydrogenase/0.441
4r8hSP1cAMP-activated global transcriptional regulator CRP/0.441
4wa9AXITyrosine-protein kinase ABL12.7.10.20.441
4yntFDAGlucose oxidase, putative/0.441
5a27MYAGlycylpeptide N-tetradecanoyltransferase/0.441
5c41ACPRibokinase/0.441
5iubCLRAdenosine receptor A2a/0.441
6adhNADAlcohol dehydrogenase E chain1.1.1.10.441
1di8DTQCyclin-dependent kinase 22.7.11.220.440
1dr5NAPDihydrofolate reductase1.5.1.30.440
1hf3NADAlcohol dehydrogenase E chain1.1.1.10.440
1mesDMPGag-Pol polyprotein3.4.23.160.440
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.440
1tehNADAlcohol dehydrogenase class-31.1.1.10.440
1tj0FADBifunctional protein PutA1.5.5.20.440
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.440
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.440
2g1o2IGRenin3.4.23.150.440
2g1s4IGRenin3.4.23.150.440
2gejGDDPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.440
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.440
2wesFADTryptophan 5-halogenase/0.440
2wo7ASVIsopenicillin N synthase1.21.3.10.440
2x9fX9FEphrin type-B receptor 42.7.10.10.440
2xhd7T9Glutamate receptor 2/0.440
3b2eADPATPase GET3/0.440
3b895GP16S rRNA methylase/0.440
3cp9C19Vascular endothelial growth factor receptor 22.7.10.10.440
3gwdFADCyclohexanone monooxygenase/0.440
3hz5Z64Heat shock protein HSP 90-alpha/0.440
3i59N6SCRP-like cAMP-activated global transcriptional regulator/0.440
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.440
3l8xN4DMitogen-activated protein kinase 14/0.440
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.440
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.440
3r5zF42Uncharacterized protein/0.440
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.440
3tdaPN0Cytochrome P450 2D6/0.440
3tqhNDPQuinone oxidoreductase/0.440
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.440
3zh8C58Protein kinase C iota type2.7.11.130.440
3znpFADD-amino-acid oxidase1.4.3.30.440
4a32MYAGlycylpeptide N-tetradecanoyltransferase/0.440
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.440
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
4c4g7RODual specificity protein kinase TTK2.7.12.10.440
4enhFVXCholesterol 24-hydroxylase/0.440
4fz70VHTyrosine-protein kinase SYK2.7.10.20.440
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.440
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.440
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.440
4l8u9AZSerum albumin/0.440
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.440
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.440
4o701QKBromodomain-containing protein 4/0.440
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.440
4ryvZEAProtein LlR18A/0.440
4utdACPAurora kinase A2.7.11.10.440
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.440
5cdgPFBAlcohol dehydrogenase E chain1.1.1.10.440
5kj6NAJAlcohol dehydrogenase E chain1.1.1.10.440