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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3gc52MQQueuine tRNA-ribosyltransferase2.4.2.29

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3gc52MQQueuine tRNA-ribosyltransferase2.4.2.291.000
1q63AIQQueuine tRNA-ribosyltransferase2.4.2.290.607
3gc4AAQQueuine tRNA-ribosyltransferase2.4.2.290.599
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.587
3sm0AEKQueuine tRNA-ribosyltransferase2.4.2.290.579
3ge7AFQQueuine tRNA-ribosyltransferase2.4.2.290.576
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.558
2qzrS79Queuine tRNA-ribosyltransferase2.4.2.290.551
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.543
2z1wBDIQueuine tRNA-ribosyltransferase2.4.2.290.535
3imgBZ3Pantothenate synthetase6.3.2.10.535
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.530
1q4wDQUQueuine tRNA-ribosyltransferase2.4.2.290.529
1f3eDPZQueuine tRNA-ribosyltransferase2.4.2.290.519
2bbf344Queuine tRNA-ribosyltransferase2.4.2.290.519
2z1xPRFQueuine tRNA-ribosyltransferase2.4.2.290.517
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.512
4fps0UXQueuine tRNA-ribosyltransferase2.4.2.290.511
1n2vBDIQueuine tRNA-ribosyltransferase2.4.2.290.509
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.508
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.508
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.505
3qgf46FGenome polyprotein2.7.7.480.505
1efzPRFQueuine tRNA-ribosyltransferase2.4.2.290.502
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.502
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.497
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.497
1kruIPTGalactoside O-acetyltransferase2.3.1.180.495
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.495
2cftPLPPyridoxal phosphate phosphatase/0.494
3gncQQQGlutaryl-CoA dehydrogenase/0.493
4s1iPLPPyridoxal kinase, putative/0.491
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.489
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.488
4rv9SAHD-mycarose 3-C-methyltransferase/0.488
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.487
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.487
4m83ERYOleandomycin glycosyltransferase2.4.10.487
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.485
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.484
4giy0WYQueuine tRNA-ribosyltransferase2.4.2.290.484
4ktkKTKCytochrome P450/0.484
2ejzSAHDiphthine synthase/0.483
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.483
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.481
1rftPXMPyridoxal kinase2.7.1.350.481
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.481
4bftZVTPantothenate kinase2.7.1.330.481
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.480
2w6zL21Biotin carboxylase6.3.4.140.480
3tneRITCandidapepsin-13.4.23.240.480
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.479
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.479
3rsv3RSBeta-secretase 13.4.23.460.479
4fr10V2Queuine tRNA-ribosyltransferase2.4.2.290.479
2x06NADL-sulfolactate dehydrogenase/0.478
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.478
4m9aFDAAcyl-CoA dehydrogenase/0.478
1towCRZFatty acid-binding protein, adipocyte/0.477
3rtnRTNBeta-secretase 13.4.23.460.477
1y5wNEZQueuine tRNA-ribosyltransferase2.4.2.290.476
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.476
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.476
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.476
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.476
5jy1NADPutative short-chain dehydrogenase/reductase/0.476
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.475
2ed3SAHDiphthine synthase/0.475
1touB1VFatty acid-binding protein, adipocyte/0.474
2j9hGTXGlutathione S-transferase P2.5.1.180.474
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.474
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
3udn09BBeta-secretase 13.4.23.460.474
4ips1G4Mycocyclosin synthase1.14.21.90.474
1ay0TPPTransketolase 12.2.1.10.473
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.473
2ij7TPFMycocyclosin synthase1.14.21.90.473
2ztsADPUncharacterized protein/0.473
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.473
1bk0ACVIsopenicillin N synthase1.21.3.10.472
1juvNDPDihydrofolate reductase1.5.1.30.472
1p0ePRFQueuine tRNA-ribosyltransferase2.4.2.290.472
1x28PGUAspartate aminotransferase2.6.1.10.472
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.472
3c1y2BADNA integrity scanning protein DisA/0.472
4j7gTRHPCZA361.3/0.472
3ssoSAHMycinamicin VI 2''-O-methyltransferase/0.471
3sufSUEPolyprotein/0.471
1ivsVAAValine--tRNA ligase6.1.1.90.470
1rxjBNIStreptavidin/0.470
1ygkRRCPyridoxal kinase2.7.1.350.470
2f2sCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.470
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.470
3udk095Beta-secretase 13.4.23.460.470
4araC56Acetylcholinesterase3.1.1.70.470
4bfzZVZPantothenate kinase2.7.1.330.470
4dptAGSMevalonate diphosphate decarboxylase/0.470
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.470
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.470
1a9cGTPGTP cyclohydrolase 13.5.4.160.469
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.469
1yhjR6CPyridoxal kinase2.7.1.350.469
2z6rSAHDiphthine synthase/0.469
3af1GDPPantothenate kinase2.7.1.330.469
3fr5I4AFatty acid-binding protein, adipocyte/0.469
3fvqATPFe(3+) ions import ATP-binding protein FbpC/0.469
4bfuZVUPantothenate kinase2.7.1.330.469
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.469
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.469
2ed5SAHDiphthine synthase/0.468
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.468
2gjnFMNNitronate monooxygenase1.13.12.160.468
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.468
3rdqDTBStreptavidin/0.468
3wagTYDGlycosyltransferase/0.468
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.290.468
4tx9AMZPhosphoribosyl isomerase A/0.468
1kvkATPMevalonate kinase2.7.1.360.467
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.467
1yw8A75Methionine aminopeptidase 2/0.467
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.467
2zu8GDDMannosyl-3-phosphoglycerate synthase2.4.1.2170.467
3fpzAHZThiamine thiazole synthase/0.467
3gusN11Glutathione S-transferase P2.5.1.180.467
3h06VBPGlutamate receptor 2/0.467
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.467
4eu4COASuccinyl-CoA:acetate CoA-transferase/0.467
4gkt0O1Queuine tRNA-ribosyltransferase2.4.2.290.467
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.467
1i59ANPChemotaxis protein CheA2.7.13.30.466
2ea2F77Methionine aminopeptidase 2/0.466
2p6kSAHDiphthine synthase/0.466
3ivcFG4Pantothenate synthetase6.3.2.10.466
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.466
3qiyQI1Botulinum neurotoxin type A3.4.24.690.466
2hxzH7JCathepsin S3.4.22.270.465
2pswCOAN-alpha-acetyltransferase 50/0.465
2x9dITCTetracycline repressor protein class D/0.465
3br3ETHTH-type transcriptional regulator QacR/0.465
4ijrNDPD-arabinose dehydrogenase [NAD(P)+] heavy chain1.1.1.1170.465
1eyqNARChalcone--flavonone isomerase 15.5.1.60.464
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.464
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.464
1xddAAYIntegrin alpha-L/0.464
2clmF6FTryptophan synthase alpha chain/0.464
2e8rSAHDiphthine synthase/0.464
2y6fM9FIsopenicillin N synthase1.21.3.10.464
2zsdCOAPantothenate kinase2.7.1.330.464
3cow52HPantothenate synthetase6.3.2.10.464
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3rbaCODPhosphopantetheine adenylyltransferase/0.464
4bfxZVXPantothenate kinase2.7.1.330.464
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.464
4pkwGM6Lethal factor3.4.24.830.464
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.464
1aqv0HGGlutathione S-transferase P2.5.1.180.463
1ascNPLAspartate aminotransferase2.6.1.10.463
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.463
1n3sGTPGTP cyclohydrolase 13.5.4.160.463
1p0ySAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.463
1q84TZ4Acetylcholinesterase3.1.1.70.463
1vbiNADMalate/L-lactate dehydrogenase family protein/0.463
1vhzAPRADP compounds hydrolase NudE3.6.10.463
1x1cSAHC-20 methyltransferase/0.463
1z0dGDPRas-related protein Rab-5C/0.463
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.463
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.463
3fhxPXLPyridoxal kinase2.7.1.350.463
3in6FMNUncharacterized protein/0.463
3r7kFDAProbable acyl CoA dehydrogenase/0.463
4df2FMNNADPH dehydrogenase/0.463
4obuPLPPyridoxal-dependent decarboxylase domain protein/0.463
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.462
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.462
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.462
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.462
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.462
2pb6SAHDiphthine synthase/0.462
2pckSAHDiphthine synthase/0.462
2wjoQUDBeta-secretase 13.4.23.460.462
4bb2STRCorticosteroid-binding globulin/0.462
4hy6FJ1Heat shock protein HSP 90-alpha/0.462
2e16SAHDiphthine synthase/0.461
2f3rG5PGuanylate kinase2.7.4.80.461
2gevCOKPantothenate kinase2.7.1.330.461
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.461
3arvSAUChitinase A/0.461
3d4pNADL-lactate dehydrogenase 11.1.1.270.461
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3sf6FDAGlutaryl-CoA dehydrogenase/0.461
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.461
4iarERM5-hydroxytryptamine receptor 1B/0.461
1bwlFMNNADPH dehydrogenase 11.6.99.10.460
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.460
1nceCB3Thymidylate synthase/0.460
1x1aSAMC-20 methyltransferase/0.460
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.460
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.460
3eon341Glutaryl-CoA dehydrogenase/0.460
3iobA4DPantothenate synthetase6.3.2.10.460
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.460
3ts1TYATyrosine--tRNA ligase6.1.1.10.460
4fsa0V3Queuine tRNA-ribosyltransferase2.4.2.290.460
4isk1JYThymidylate synthase/0.460
4n4v2GYTankyrase-12.4.2.300.460
4pnmNU1Tankyrase-22.4.2.300.460
1a9p9DIPurine nucleoside phosphorylase2.4.2.10.459
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.459
1zgbA1EAcetylcholinesterase3.1.1.70.459
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.459
2dsiSAHDiphthine synthase/0.459
2dv4SAHDiphthine synthase/0.459
2el0SAHDiphthine synthase/0.459
2owuSAHDiphthine synthase/0.459
2w6oOA3Biotin carboxylase6.3.4.140.459
3g5hYTTMycocyclosin synthase1.14.21.90.459
3gwfFADCyclohexanone monooxygenase/0.459
3ig6438Urokinase-type plasminogen activator3.4.21.730.459
3tifADPUncharacterized ABC transporter ATP-binding protein MJ0796/0.459
4xbfFADLysine-specific histone demethylase 1A10.459
1trkTPPTransketolase 12.2.1.10.458
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.458
1x1dSAHC-20 methyltransferase/0.458
1y5vNE8Queuine tRNA-ribosyltransferase2.4.2.290.458
2gjlFMNNitronate monooxygenase1.13.12.160.458
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.458
3fpkFADFerredoxin-NADP reductase/0.458
3pqbVGPPutative oxidoreductase/0.458
3udq09EBeta-secretase 13.4.23.460.458
4g7gVFVLanosterol 14-alpha-demethylase/0.458
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.458
4ycpFMNtRNA-dihydrouridine(16) synthase/0.458
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.458
1n2hPAJPantothenate synthetase6.3.2.10.457
1rzuADPGlycogen synthase 12.4.1.210.457
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.457
1tojHCIAspartate aminotransferase2.6.1.10.457
1vceSAHDiphthine synthase/0.457
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.457
2qw034Z4-chlorobenzoyl CoA ligase/0.457
2v2qNVG4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.457
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.457
2w02ATPAcsD/0.457
3coz54HPantothenate synthetase6.3.2.10.457
3otwCOAPhosphopantetheine adenylyltransferase/0.457
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.457
4h0yLARActin, alpha skeletal muscle/0.457
2c29NAPDihydroflavonol 4-reductase/0.456
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.456
2cleF6FTryptophan synthase alpha chain/0.456
2e94364Geranylgeranyl pyrophosphate synthase/0.456
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.456
2x3jATPAcsD/0.456
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.456
3anmSYD1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.456
3hkyIX6Genome polyprotein2.7.7.480.456
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3ohh3HHBeta-secretase 13.4.23.460.456
3ox4NADAlcohol dehydrogenase 21.1.1.10.456
3ufl508Beta-secretase 13.4.23.460.456
3uk6ADPRuvB-like 23.6.4.120.456
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.456
4i9h1E4L-lactate dehydrogenase A chain1.1.1.270.456
1je1GMPPurine nucleoside phosphorylase/0.455
1kziTHGThymidylate synthase/0.455
1swgBTNStreptavidin/0.455
1typFADTrypanothione reductase1.8.1.120.455
2h21SAMRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.455
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.455
2x7tWZBCarbonic anhydrase 24.2.1.10.455
3hl0NADMaleylacetate reductase/0.455
3qftFADNADPH--cytochrome P450 reductase/0.455
3qt62P0Mevalonate diphosphate decarboxylase/0.455
4d9fDCSD-cysteine desulfhydrase/0.455
4fhf0TTSpore photoproduct lyase/0.455
4fhpUTPTerminal uridylyltransferase cid1/0.455
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.455
4l3q926Glucokinase2.7.1.20.455
4y380A9Endothiapepsin3.4.23.220.455
1queFADFerredoxin--NADP reductase1.18.1.20.454
1sxjAGSReplication factor C subunit 1/0.454
2eldSAHDiphthine synthase/0.454
2g226IGRenin3.4.23.150.454
3fp0FP015-O-acetyltransferase/0.454
3mauEXTPutative sphingosine-1-phosphate lyase/0.454
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.454
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.454
4j7hTRHPCZA361.3/0.454
4jlm1NNDeoxycytidine kinase2.7.1.740.454
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.454
1a8rGTPGTP cyclohydrolase 13.5.4.160.453
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.453
1l8qADPChromosomal replication initiator protein DnaA/0.453
1ove358Mitogen-activated protein kinase 14/0.453
2bgiFADNADPH:ferredoxin reductase/0.453
2emuSAHDiphthine synthase/0.453
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.453
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
2p6lSAHDiphthine synthase/0.453
2p8hMY9Beta-secretase 13.4.23.460.453
2ptfFMNUncharacterized protein MTH_863/0.453
2yk2YJXHeat shock protein HSP 90-alpha/0.453
3af0GDPPantothenate kinase2.7.1.330.453
3biz61EWee1-like protein kinase2.7.10.20.453
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.453
3c35KAIGlutamate receptor ionotropic, kainate 1/0.453
3cx8GSPGuanine nucleotide-binding protein subunit alpha-13/0.453
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.453
3jv7NADSecondary alcohol dehydrogenase/0.453
3nx2FERFerulic acid decarboxylase/0.453
4a83DXCMajor pollen allergen Bet v 1-A/0.453
4gd9BTNStreptavidin/0.453
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
4o9kCMKArabinose 5-phosphate isomerase/0.453
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.452
1odcA8BAcetylcholinesterase3.1.1.70.452
1qorNDPQuinone oxidoreductase 1/0.452
1x1bSAHC-20 methyltransferase/0.452
1xvaSAMGlycine N-methyltransferase2.1.1.200.452
2huvSAHDiphthine synthase/0.452
2r8oT5XTransketolase 1/0.452
2xb9XNW3-dehydroquinate dehydratase4.2.1.100.452
2ym1FADPhenylacetone monooxygenase1.14.13.920.452
3akzGSUGlutamate--tRNA ligase 2/0.452
3fr4F8AFatty acid-binding protein, adipocyte/0.452
3ihgVAKAklavinone 12-hydroxylase RdmE/0.452
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3qizQI2Botulinum neurotoxin type A3.4.24.690.452
3udj092Beta-secretase 13.4.23.460.452
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.452
3zeiAWHO-acetylserine sulfhydrylase/0.452
4dx7DM2Multidrug efflux pump subunit AcrB/0.452
4g3jVNTLanosterol 14-alpha-demethylase/0.452
1a5bIGPTryptophan synthase alpha chain/0.451
1zgv501Prothrombin3.4.21.50.451
2briANPUridylate kinase2.7.4.220.451
2e8sSAHDiphthine synthase/0.451
2rlcCHDCholoylglycine hydrolase3.5.1.240.451
2z4zSC0Geranylgeranyl pyrophosphate synthase/0.451
2zrfDTPProtein RecA/0.451
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.451
3c1oNAPEugenol synthase/0.451
3e6eDCSAlanine racemase/0.451
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.451
3kmyD8YBeta-secretase 13.4.23.460.451
3ld6BCDLanosterol 14-alpha demethylase1.14.13.700.451
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.451
4frkDWDBeta-secretase 13.4.23.460.451
4g47TZFMycocyclosin synthase1.14.21.90.451
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.451
4rphGDUUDP-galactopyranose mutase5.4.99.90.451
4v12POGMaoC like domain protein/0.451
5jscFADPutative acyl-CoA dehydrogenase/0.451
7stdCRPScytalone dehydratase4.2.1.940.451
1c7oPPGHemolysin/0.450
1udaUFGUDP-glucose 4-epimerase5.1.3.20.450
1wuuANPGalactokinase2.7.1.60.450
2abaSTRPentaerythritol tetranitrate reductase/0.450
2eeqSAHDiphthine synthase/0.450
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2p6dSAHDiphthine synthase/0.450
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3hdqGDUUDP-galactopyranose mutase/0.450
3hk1B64Fatty acid-binding protein, adipocyte/0.450
3nxyD2HDihydrofolate reductase1.5.1.30.450
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.450
3pfdFDAAcyl-CoA dehydrogenase FadE25/0.450
3q43D66M1 family aminopeptidase3.4.110.450
3rykTYDdTDP-4-dehydrorhamnose 3,5-epimerase/0.450
3uqdADPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.450
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.450
4ktl1CQCytochrome P450/0.450
4ocvANPAminoglycoside phosphotransferase/0.450
4tl9AGSCircadian clock protein kinase KaiC2.7.11.10.450
4wudANPDNA gyrase subunit B/0.450
1pgtGTXGlutathione S-transferase P2.5.1.180.449
1qtqQSIGlutamine--tRNA ligase6.1.1.180.449
1rdwLARActin, alpha skeletal muscle/0.449
1sm4FADFerredoxin--NADP reductase/0.449
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.449
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.449
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.449
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.449
2z54AB1Gag-Pol polyprotein3.4.23.160.449
3fql79ZGenome polyprotein2.7.7.480.449
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3kr8XAVTankyrase-22.4.2.300.449
3nmpPYVAbscisic acid receptor PYL2/0.449
3nxxNDPDihydrofolate reductase1.5.1.30.449
3sl2ATPSensor histidine kinase WalK/0.449
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.449
4b1e6T6Beta-secretase 13.4.23.460.449
4ddhMS0Pantothenate synthetase6.3.2.10.449
4jeyPLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.449
5f54TMPSingle-stranded-DNA-specific exonuclease/0.449
1dr3TAPDihydrofolate reductase1.5.1.30.448
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.448
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.448
1gc5ADPADP-dependent glucokinase2.7.1.1470.448
1lv89PPPurine nucleoside phosphorylase2.4.2.10.448
1me6IVSPlasmepsin-23.4.23.390.448
1msmJE2Gag-Pol polyprotein3.4.23.160.448
1n2eAPCPantothenate synthetase6.3.2.10.448
2bf4FMNNADPH--cytochrome P450 reductase/0.448
2hk9NAPShikimate dehydrogenase (NADP(+))/0.448
2iviACWIsopenicillin N synthase1.21.3.10.448
2o7pNAPRiboflavin biosynthesis protein RibD/0.448
2p5fSAHDiphthine synthase/0.448
2wo7ASVIsopenicillin N synthase1.21.3.10.448
3dj4UD1Bifunctional protein GlmU/0.448
3h3t16HCollagen type IV alpha-3-binding protein/0.448
3hdyGDUUDP-galactopyranose mutase/0.448
3ioeA7DPantothenate synthetase6.3.2.10.448
4dpuAGSMevalonate diphosphate decarboxylase/0.448
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.448
4g090VDHistidinol dehydrogenase/0.448
4ryvZEAProtein LlR18A/0.448
4y3jHICEndothiapepsin3.4.23.220.448
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.448
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.447
1ahgTYR_PLPAspartate aminotransferase2.6.1.10.447
1dljUGAUDP-glucose 6-dehydrogenase/0.447
1drhNAPDihydrofolate reductase1.5.1.30.447
1h74ADPHomoserine kinase2.7.1.390.447
1lkeDOGBilin-binding protein/0.447
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.447
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.447
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.447
1tqf32PBeta-secretase 13.4.23.460.447
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
2ab8MTPAdenosine kinase2.7.1.200.447
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.447
2i7nACOPantothenate kinase 12.7.1.330.447
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.447
2trsPLSTryptophan synthase beta chain4.2.1.200.447
2vcmM11Isopenicillin N synthase1.21.3.10.447
3gbuATPUncharacterized sugar kinase PH14592.7.10.447
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.447
3q3cNADNAD-dependent L-serine dehydrogenase/0.447
3q9bB3NAcetylpolyamine amidohydrolase/0.447
3t82SG4Carbonic anhydrase 24.2.1.10.447
3wquATPCell division protein FtsA/0.447
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.447
3ziuLSSLeucyl-tRNA synthetase/0.447
4acuQN7Beta-secretase 13.4.23.460.447
4b68NAPL-ornithine N(5)-monooxygenase/0.447
4fsl0VBBeta-secretase 13.4.23.460.447
4fv7E94Mitogen-activated protein kinase 12.7.11.240.447
4iilRBFMembrane lipoprotein TpN38(b)/0.447
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.447
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.447
1ez0NAPNADP-dependent fatty aldehyde dehydrogenase1.2.1.40.446
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.446
1r5yDQUQueuine tRNA-ribosyltransferase2.4.2.290.446
1waj5GPDNA-directed DNA polymerase/0.446
1ywgNADGlyceraldehyde-3-phosphate dehydrogenase/0.446
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.446
2e4nSAHDiphthine synthase/0.446
2hm1LIQBeta-secretase 13.4.23.460.446
2tysPLTTryptophan synthase beta chain4.2.1.200.446
2zsaADPPantothenate kinase2.7.1.330.446
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.446
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.446
3slkNDPPolyketide synthase extender module 2/0.446
4b7754MBeta-secretase 13.4.23.460.446
4gg90WWQueuine tRNA-ribosyltransferase2.4.2.290.446
4ke11R6Beta-secretase 13.4.23.460.446
4mv8ACPBiotin carboxylase6.3.4.140.446
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.446
1dr2TAPDihydrofolate reductase1.5.1.30.445
1e66HUXAcetylcholinesterase3.1.1.70.445
1ja0FADNADPH--cytochrome P450 reductase/0.445
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
1qy8RDIEndoplasmin/0.445
1s4oGDPGlycolipid 2-alpha-mannosyltransferase/0.445
2dsgSAHDiphthine synthase/0.445
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.445
2flhZEACytokinin-specific binding protein/0.445
2g8yNADHydroxycarboxylate dehydrogenase B/0.445
2gv8NDPThiol-specific monooxygenase1.14.130.445
2npxNADNADH peroxidase1.11.1.10.445
3e23SAMUncharacterized protein/0.445
3iocA5DPantothenate synthetase6.3.2.10.445
3l7gM44Xaa-Pro dipeptidase3.4.13.90.445
3p67FMNPentaerythritol tetranitrate reductase/0.445
3p74FMNPentaerythritol tetranitrate reductase/0.445
3vaxPLPUncharacterized protein/0.445
4iah1DXAlr2278 protein/0.445
4jtqNAPAldo-keto reductase family 1 member C2/0.445
4jxxATPGlutamine--tRNA ligase6.1.1.180.445
4k6fNAPPutative Acetoacetyl-CoA reductase/0.445
4l33F70Tankyrase-22.4.2.300.445
4qlyFMNEnone reductase CLA-ER/0.445
1dr5NAPDihydrofolate reductase1.5.1.30.444
1lbcCYZGlutamate receptor 2/0.444
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.444
2eh5SAHDiphthine synthase/0.444
2hp2KE4Glutamate-1-semialdehyde 2,1-aminomutase5.4.3.80.444
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2rc6FADFerredoxin--NADP reductase/0.444
2vwqNAPGlucose 1-dehydrogenase/0.444
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.444
3cgyRDCVirulence sensor histidine kinase PhoQ2.7.13.30.444
3h3r14HCollagen type IV alpha-3-binding protein/0.444
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.444
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.444
3lzwNAPFerredoxin--NADP reductase 21.18.1.20.444
3o0qADNVitamin B12-dependent ribonucleotide reductase/0.444
4m5pFMNNADPH dehydrogenase/0.444
4ubfADPKinesin-like protein KIF2C/0.444
9gssGTXGlutathione S-transferase P2.5.1.180.444
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.443
1krv147Galactoside O-acetyltransferase2.3.1.180.443
1n77ATPGlutamate--tRNA ligase6.1.1.170.443
1t0iFMNNAD(P)H-dependent FMN reductase LOT6/0.443
1x8lOXRRetinol dehydratase/0.443
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2bi4NADLactaldehyde reductase1.1.1.770.443
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.443
2hdjNDPAldo-keto reductase family 1 member C2/0.443
2p2qPRXAcetyl-coenzyme A synthetase/0.443
2tdmUMPThymidylate synthase/0.443
2v58LZJBiotin carboxylase6.3.4.140.443
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.443
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.443
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.443
3wdsNADNADH-dependent quinuclidinone reductase/0.443
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.443
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.443
4g3pUD1Bifunctional protein GlmU/0.443
4i8zG08Gag-Pol polyprotein3.4.23.160.443
4iq71G9Mycocyclosin synthase1.14.21.90.443
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.443
4u0mGTPCyclic GMP-AMP synthase/0.443
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.443
5hg0SAMPantothenate synthetase/0.443
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.442
1ivrCBAAspartate aminotransferase, mitochondrial2.6.1.10.442
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1mp0NADAlcohol dehydrogenase class-31.1.1.10.442
1mxfMTXPutative pteridine reductase 2/0.442
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.442
1txtCAAHMG-CoA synthase/0.442
1vf2GTXGlutathione S-transferase 32.5.1.180.442
1vgqCAOFormyl-CoA:oxalate CoA-transferase/0.442
1xf0ASDAldo-keto reductase family 1 member C3/0.442
1yjqNAP2-dehydropantoate 2-reductase1.1.1.1690.442
1zapA70Candidapepsin-23.4.23.240.442
2b53D23Cyclin-dependent kinase 22.7.11.220.442
2g0nGDPRas-related C3 botulinum toxin substrate 3/0.442
2oadGTBGlutathione S-transferase P 12.5.1.180.442
2p5cSAHDiphthine synthase/0.442
2pb4SAHDiphthine synthase/0.442
3b2sB2STrichothecene 3-O-acetyltransferase/0.442
3bk2U5PRibonuclease J/0.442
3oiaA31Camphor 5-monooxygenase1.14.15.10.442
3q70RITCandidapepsin-23.4.23.240.442
3qj0QI3Botulinum neurotoxin type A3.4.24.690.442
3ukoNADAlcohol dehydrogenase class-3/0.442
3wqmB29Diterpene synthase3.1.7.80.442
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.442
4aosFADSteroid monooxygenase/0.442
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.442
4jyzATPGlutamine--tRNA ligase6.1.1.180.442
4l4fCAMCamphor 5-monooxygenase1.14.15.10.442
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.442
4nmbFADBifunctional protein PutA/0.442
4prxADPDNA gyrase subunit B/0.442
4qzuRTLRetinol-binding protein 2/0.442
4r81FMNPredicted NADH dehydrogenase/0.442
5cpmFNRNADH:flavin oxidoreductase/0.442
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.442
1b2lNDCAlcohol dehydrogenase1.1.1.10.441
1bn3AL6Carbonic anhydrase 24.2.1.10.441
1gaxVAAValine--tRNA ligase6.1.1.90.441
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
1q1gMTIPurine nucleoside phosphorylase/0.441
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
2a9y26AAdenosine kinase2.7.1.200.441
2e07SAHDiphthine synthase/0.441
2el3SAHDiphthine synthase/0.441
2gesCOKPantothenate kinase2.7.1.330.441
2h2eSA8Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.441
2jb4A14Isopenicillin N synthase1.21.3.10.441
2yj4ATPCopper-transporting ATPase/0.441
2z4sADPChromosomal replication initiator protein DnaA/0.441
2zhe13UProthrombin3.4.21.50.441
3au2DGTDNA polymerase beta family (X family)/0.441
3coy53HPantothenate synthetase6.3.2.10.441
3csoXNIGenome polyprotein2.7.7.480.441
3docNADGlyceraldehyde-3-phosphate dehydrogenase/0.441
3ooiSAMHistone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific2.1.1.430.441
3owaFADAcyl-CoA dehydrogenase/0.441
3q44D50M1 family aminopeptidase3.4.110.441
4a4qUX9Pol protein/0.441
4c717RD3-oxoacyl-ACP synthase/0.441
4hshQEIQueuine tRNA-ribosyltransferase2.4.2.290.441
4ipw1G7Mycocyclosin synthase1.14.21.90.441
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.441
4k38SAMAnaerobic sulfatase-maturating enzyme1.8.980.441
4kx6FADFumarate reductase flavoprotein subunit1.3.5.40.441
4l7h1W1Beta-secretase 13.4.23.460.441
4lzwTHMUridine phosphorylase/0.441
4pgtGBXGlutathione S-transferase P2.5.1.180.441
4q0kGA3Phytohormone-binding protein/0.441
4tl6ANPCircadian clock protein kinase KaiC2.7.11.10.441
4ttcFMNIodotyrosine deiodinase 1/0.441
3vw7VPXProteinase-activated receptor 1/0.441
17gsGTXGlutathione S-transferase P2.5.1.180.440
1gqyACPUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.440
1kp3ATPArgininosuccinate synthase6.3.4.50.440
1psa0ZLPepsin A3.4.23.10.440
1thnADPAnti-sigma F factor/0.440
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.440
1z71L17Prothrombin3.4.21.50.440
2a94AP0L-lactate dehydrogenase1.1.1.270.440
2cekN8TAcetylcholinesterase3.1.1.70.440
2dekSAHDiphthine synthase/0.440
2futH1SHeparin and heparin-sulfate lyase/0.440
2hveADPNucleoside diphosphate kinase A2.7.4.60.440
2ji6TPWOxalyl-CoA decarboxylase4.1.1.80.440
2mokFMNFlavodoxin 1/0.440
2p83MR0Beta-secretase 13.4.23.460.440
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.440
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.440
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.440
2x7hPFNProstaglandin reductase 310.440
2xvv9DNSerum albumin/0.440
2xx91NFGlutamate receptor 2/0.440
2zc922UProthrombin3.4.21.50.440
2zi224UProthrombin3.4.21.50.440
3ag6PAJPantothenate synthetase/0.440
3b6pTMPThree-prime repair exonuclease 13.1.11.20.440
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3c212BADNA integrity scanning protein DisA/0.440
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.440
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.440
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.440
3o26NDPSalutaridine reductase/0.440
3pdnSFGHistone-lysine N-methyltransferase SMYD32.1.1.430.440
3sigAR6Uncharacterized protein/0.440
3ssmSAHMycinamicin VI 2''-O-methyltransferase/0.440
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.440
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.440
4d89BXDBeta-secretase 13.4.23.460.440
4eb5PLPCysteine desulfurase IscS 2/0.440
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.440
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.440
4kkyCAMCamphor 5-monooxygenase1.14.15.10.440
4rrrA3TThreonine--tRNA ligase6.1.1.30.440
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.440
4yaw2AMNADPH--cytochrome P450 reductase/0.440