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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.26

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.261.000
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.621
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.609
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.592
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.589
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.586
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.568
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.559
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.551
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.550
2jedLG8Protein kinase C theta type2.7.11.130.549
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.548
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.547
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.546
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.543
3du8553Glycogen synthase kinase-3 beta2.7.11.260.539
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.539
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.538
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.537
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.535
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.535
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.534
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.532
3e5aVX6Aurora kinase A2.7.11.10.529
2i0ePDSProtein kinase C beta type2.7.11.130.525
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.524
4bchT7ZCyclin-dependent kinase 92.7.11.220.524
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.522
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.519
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.518
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.517
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.516
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.514
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.512
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.511
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
4ix6ADPUncharacterized protein/0.510
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.507
1zeoC01Peroxisome proliferator-activated receptor gamma/0.506
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.506
3l0lHC3Nuclear receptor ROR-gamma/0.504
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.504
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.503
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.501
3iw4LW4Protein kinase C alpha type2.7.11.130.500
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.500
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.500
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.500
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.500
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.497
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.494
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.493
4othDRNSerine/threonine-protein kinase N1/0.493
1e7aPFLSerum albumin/0.492
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.492
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.491
4ykfFADAlkyl hydroperoxide reductase subunit F1.8.10.491
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.490
3a60STURibosomal protein S6 kinase beta-12.7.11.10.489
3blrCPBCyclin-dependent kinase 92.7.11.220.489
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.489
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.489
1kkq471Peroxisome proliferator-activated receptor alpha/0.488
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.488
2ptfFMNUncharacterized protein MTH_863/0.488
2zjwREFCasein kinase II subunit alpha2.7.11.10.488
4nb6444Nuclear receptor ROR-gamma/0.488
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.488
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.487
3gc9B45Mitogen-activated protein kinase 112.7.11.240.487
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.487
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.487
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.486
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.486
1x8lOXRRetinol dehydratase/0.485
2itqITQEpidermal growth factor receptor2.7.10.10.485
2po7CHDFerrochelatase, mitochondrial4.99.1.10.485
2x7hPFNProstaglandin reductase 310.485
3t2kFADSulfide-quinone reductase/0.485
4nm7ADPGlycogen synthase kinase-3 beta2.7.11.260.485
3bfa9ODOdorant binding protein ASP1/0.484
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.484
4dymIYZActivin receptor type-12.7.11.300.484
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.484
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.484
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.483
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.483
3adaNADSubunit alpha of sarocosine oxidase/0.483
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.483
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.483
3vo30KFVascular endothelial growth factor receptor 22.7.10.10.483
4gk4L90Ephrin type-A receptor 32.7.10.10.483
1oiyN41Cyclin-dependent kinase 22.7.11.220.482
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.482
3lu8IQXSerum albumin/0.482
3oom507Activin receptor type-12.7.11.300.482
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.482
4g2fC07Ephrin type-A receptor 32.7.10.10.482
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.482
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.481
3eb0DRKUncharacterized protein/0.481
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
4g3jVNTLanosterol 14-alpha-demethylase/0.481
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.481
4lopSB4Mitogen-activated protein kinase 14/0.481
4qa0SHHHistone deacetylase 83.5.1.980.481
1bygSTUTyrosine-protein kinase CSK/0.480
1y0s331Peroxisome proliferator-activated receptor delta/0.480
2q9fC3SCholesterol 24-hydroxylase/0.480
3zh8C58Protein kinase C iota type2.7.11.130.480
3pe6ZYHMonoglyceride lipase/0.479
1qoqIGPTryptophan synthase alpha chain/0.478
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.478
2vwx7X4Ephrin type-B receptor 42.7.10.10.478
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.478
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.478
4bgg844Activin receptor type-12.7.11.300.478
4uymVOR14-alpha sterol demethylase Cyp51B/0.478
2uxuNARHTH-type transcriptional regulator TtgR/0.477
2vcmM11Isopenicillin N synthase1.21.3.10.477
2yxuATPPyridoxal kinase2.7.1.350.477
3l6jZ90Alr2278 protein/0.477
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.477
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.477
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.476
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.476
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.476
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.476
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.476
1kl2FONSerine hydroxymethyltransferase/0.475
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.475
2qo9ANPEphrin type-A receptor 32.7.10.10.475
3kytHC2Nuclear receptor ROR-gamma/0.475
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.475
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.474
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.474
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.474
2hog710Serine/threonine-protein kinase Chk12.7.11.10.474
2j4z626Aurora kinase A2.7.11.10.474
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.474
2uxoTACHTH-type transcriptional regulator TtgR/0.474
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.474
2zevB71Geranylgeranyl pyrophosphate synthase/0.474
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.474
3pe2E1BCasein kinase II subunit alpha2.7.11.10.474
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.474
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.474
3reyXACAdenosine receptor A2a/0.474
3a1l2CCCytochrome P450/0.473
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.473
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.473
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.473
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.473
4i2q1BTGag-Pol polyprotein2.7.7.490.473
4iarERM5-hydroxytryptamine receptor 1B/0.473
1fmlRTLRetinol dehydratase/0.472
1s19MC9Vitamin D3 receptor/0.472
1xddAAYIntegrin alpha-L/0.472
2uxhQUEHTH-type transcriptional regulator TtgR/0.472
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.472
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.472
3c3dFO12-phospho-L-lactate transferase/0.472
3owuEQUSteroid Delta-isomerase5.3.3.10.472
3qc9ADPRhodopsin kinase/0.472
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.472
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.472
5drdATPAurora kinase A2.7.11.10.472
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.471
1fmjRTLRetinol dehydratase/0.471
1rfuADPPyridoxal kinase2.7.1.350.471
2nr4FMNConserved protein/0.471
4eilCB3Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.471
4gmy0X5Tyrosine-protein kinase JAK2/0.471
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.471
1hvyD16Thymidylate synthase2.1.1.450.470
3cyz9ODPheromone-binding protein ASP1/0.470
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.470
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
3kr6UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.470
4dbzNDPPutative ketoacyl reductase1.3.10.470
4gk2L66Ephrin type-A receptor 32.7.10.10.470
4jq8KJ8Epidermal growth factor receptor2.7.10.10.470
1k7fIAVTryptophan synthase alpha chain/0.469
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.469
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.469
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.469
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.469
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
4l9zCOAL-malyl-CoA/beta-methylmalyl-CoA lyase4.1.3.240.469
1bwlFMNNADPH dehydrogenase 11.6.99.10.468
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.468
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.468
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.468
3ctj320Hepatocyte growth factor receptor2.7.10.10.468
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.468
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.468
3zkuHCVIsopenicillin N synthase1.21.3.10.468
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.468
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.468
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.468
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.468
1dkfBMSRetinoic acid receptor alpha/0.467
1swtBTNStreptavidin/0.467
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.467
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.467
3dds26BGlycogen phosphorylase, liver form2.4.1.10.467
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.467
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.467
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.466
1lp4ANPCasein kinase II subunit alpha2.7.11.10.466
1obnASVIsopenicillin N synthase1.21.3.10.466
2hb7O1CVitamin D3 receptor/0.466
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.466
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.466
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.466
2y6o1N1Ephrin type-A receptor 42.7.10.10.466
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.466
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.466
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
4e5yNDPGDP-L-fucose synthase1.1.1.2710.466
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
4ez8DHFThymidylate synthase2.1.1.450.466
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.466
4ix5ANPUncharacterized protein/0.466
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.465
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.465
2hw2RFPRifampin ADP-ribosyl transferase/0.465
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.465
2wd9IBPAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.465
2zlcVDXVitamin D3 receptor/0.465
3dd125DGlycogen phosphorylase, liver form2.4.1.10.465
3g7jGTXGlutathione transferase GST1-4/0.465
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.465
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.465
3p8jFMNPentaerythritol tetranitrate reductase/0.465
3pl8FADPyranose 2-oxidase/0.465
3r9dX6BCyclin-dependent kinase 22.7.11.220.465
4hvh19RTyrosine-protein kinase JAK32.7.10.20.465
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.464
1r6g442Thyroid hormone receptor beta/0.464
1wsvTHHAminomethyltransferase, mitochondrial/0.464
2qocANPEphrin type-A receptor 32.7.10.10.464
2vn0TDZCytochrome P450 2C8/0.464
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.464
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.464
3arvSAUChitinase A/0.464
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.464
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.464
3jynNDPQuinone oxidoreductase/0.464
3sz0FADSulfide-quinone reductase/0.464
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.464
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.464
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.464
4a6nFADTetX family tetracycline inactivation enzyme/0.464
4bfwZVWPantothenate kinase2.7.1.330.464
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
4jbiNDPAlcohol dehydrogenase (Zinc)/0.464
4l4xNDPAmphI/0.464
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.464
4oauADP2-5A-dependent ribonuclease3.1.260.464
4oavACP2-5A-dependent ribonuclease3.1.260.464
2acxANPG protein-coupled receptor kinase 62.7.11.160.463
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.463
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.463
2xpwOTCTetracycline repressor protein class D/0.463
3bfb9ODPheromone-binding protein ASP1/0.463
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.463
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3rpr25ZCyclin-dependent kinase 22.7.11.220.463
3t2zFADSulfide-quinone reductase/0.463
4jvlESTEstrogen sulfotransferase2.8.2.40.463
4oztP1AEcdysone receptor, putative/0.463
4pd6URINucleoside permease/0.463
1g28FMNPHY3/0.462
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
1pkdUCNCyclin-dependent kinase 22.7.11.220.462
1xuoLA1Integrin alpha-L/0.462
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.462
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.462
2r3yVAL_TYR_TRP_PHESerine endoprotease DegS3.4.21.1070.462
2uxpCLMHTH-type transcriptional regulator TtgR/0.462
2x6dX6DAurora kinase A2.7.11.10.462
3i0rRT3Gag-Pol polyprotein2.7.7.490.462
3rmf20ZCyclin-dependent kinase 22.7.11.220.462
3t113T1Gag-Pol polyprotein3.4.23.160.462
3t14FADSulfide-quinone reductase/0.462
4ambDUDPutative glycosyl transferase/0.462
4g1y0VOVitamin D3 receptor A/0.462
4g7gVFVLanosterol 14-alpha-demethylase/0.462
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.462
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.462
5dp2NAPCurF/0.462
1fgiSU1Fibroblast growth factor receptor 1/0.461
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.461
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.461
1rfvADPPyridoxal kinase2.7.1.350.461
1tysDHFThymidylate synthase/0.461
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.461
2xvdAS6Ephrin type-B receptor 42.7.10.10.461
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.461
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.461
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.461
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.461
3t8oATPRhodopsin kinase/0.461
3vt5YI2Vitamin D3 receptor/0.461
3vtdTKDVitamin D3 receptor/0.461
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.461
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.461
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.461
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.461
4lsjLSJGlucocorticoid receptor/0.461
4qmySTUSerine/threonine-protein kinase 242.7.11.10.461
4tuvCPZCytochrome P450 1191.140.461
5fm7ADPRuvB-like helicase/0.461
3uzcT4EAdenosine receptor A2a/0.461
1m9m6NINitric oxide synthase, endothelial1.14.13.390.460
2bxoOPBSerum albumin/0.460
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.460
2dwbANPAurora kinase A2.7.11.10.460
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.460
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.460
3gwfNAPCyclohexanone monooxygenase/0.460
3mdvCL6Cholesterol 24-hydroxylase/0.460
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.460
3t2yFADSulfide-quinone reductase/0.460
3vtbTKAVitamin D3 receptor/0.460
4bfzZVZPantothenate kinase2.7.1.330.460
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.460
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.460
4riyADPEpidermal growth factor receptor2.7.10.10.460
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.460
4z34ON7Lysophosphatidic acid receptor 1/0.460
3sn6P0GBeta-2 adrenergic receptor/0.460
1cqp803Integrin alpha-L/0.459
1h1r6CPCyclin-dependent kinase 22.7.11.220.459
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1klkPMDDihydrofolate reductase1.5.1.30.459
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.459
1sozVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.459
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.459
2ojg19AMitogen-activated protein kinase 12.7.11.240.459
3dt1P40Mitogen-activated protein kinase 14/0.459
3hx4ANPCalmodulin-domain protein kinase 1/0.459
3nhwZXZRibosyldihydronicotinamide dehydrogenase [quinone]/0.459
4bfyZVYPantothenate kinase2.7.1.330.459
4enhFVXCholesterol 24-hydroxylase/0.459
4i6gFADCryptochrome-2/0.459
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.459
4nieNBHNuclear receptor ROR-gamma/0.459
4xwtU5PRibonuclease J/0.459
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.458
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.458
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.458
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.458
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.458
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.458
3hk1B64Fatty acid-binding protein, adipocyte/0.458
3ijdC2FMethylenetetrahydrofolate reductase/0.458
3my5RFZCyclin-dependent kinase 22.7.11.220.458
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3qlrNDPDihydrofolate reductase1.5.1.30.458
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.458
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.458
5jtbZMAAdenosine receptor A2a/0.458
1ke9LS5Cyclin-dependent kinase 22.7.11.220.457
1osvCHCBile acid receptor/0.457
2vu3LZECyclin-dependent kinase 22.7.11.220.457
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.457
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.457
3h18PMSEsterase/lipase/0.457
3h65I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.457
3qtsX46Cyclin-dependent kinase 22.7.11.220.457
3slkNDPPolyketide synthase extender module 2/0.457
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.457
4g1z0VPVitamin D3 receptor A/0.457
4ips1G4Mycocyclosin synthase1.14.21.90.457
4j97ACPFibroblast growth factor receptor 2/0.457
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.457
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.456
1p93DEXGlucocorticoid receptor/0.456
1rbzKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.456
1txiTX5Vitamin D3 receptor/0.456
2ejvNADL-threonine 3-dehydrogenase/0.456
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3d7kD7KBenzaldehyde lyase/0.456
3fln3FNMitogen-activated protein kinase 14/0.456
3gwfFADCyclohexanone monooxygenase/0.456
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.456
3ibqATPPyridoxal kinase/0.456
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.456
3qe2FADNADPH--cytochrome P450 reductase/0.456
4dgmAGICasein kinase II subunit alpha2.7.11.10.456
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.456
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.456
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.456
4jlj1NMDeoxycytidine kinase2.7.1.740.456
4jvmXDIEstrogen sulfotransferase2.8.2.40.456
4jxrACOAcetyltransferase/0.456
4wsqKSAAP2-associated protein kinase 12.7.11.10.456
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.456
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.456
1bwsNDPGDP-L-fucose synthase/0.455
1cbrREACellular retinoic acid-binding protein 1/0.455
1dduCB3Thymidylate synthase/0.455
1fm4DXCMajor pollen allergen Bet v 1-L/0.455
1os1ATPPhosphoenolpyruvate carboxykinase (ATP)/0.455
1unlRRCCyclin-dependent-like kinase 52.7.11.10.455
2fzwNADAlcohol dehydrogenase class-31.1.1.10.455
2hamC33Vitamin D3 receptor/0.455
2iw84SPCyclin-dependent kinase 22.7.11.220.455
2w05FRTCyclin-dependent kinase 22.7.11.220.455
3c50ADPRhodopsin kinase/0.455
3d75NBBPheromone-binding protein ASP1/0.455
3hub469Mitogen-activated protein kinase 14/0.455
3iaeD7KBenzaldehyde lyase/0.455
3mg3ECHOrange carotenoid-binding protein/0.455
3new3NEMitogen-activated protein kinase 14/0.455
3nj0PYVAbscisic acid receptor PYL2/0.455
3oxfSAHHistone-lysine N-methyltransferase SMYD32.1.1.430.455
3p3zP3ZPutative cytochrome P450/0.455
3roy22ZCyclin-dependent kinase 22.7.11.220.455
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.455
4g210VPVitamin D3 receptor A/0.455
4nka2K7Fibroblast growth factor receptor 1/0.455
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.455
5uviZMAAdenosine receptor A2a/0.455
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.454
1g63FMNEpidermin decarboxylase4.1.10.454
1jxzBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.454
1lriCLRBeta-elicitin cryptogein/0.454
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.454
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.454
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.454
2imkGTXAGAP009194-PA/0.454
2iorADPChaperone protein HtpG/0.454
2xlsFADPutative flavin-containing monooxygenase/0.454
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.454
3bgxMEFThymidylate synthase/0.454
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.454
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.454
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3gbuATPUncharacterized sugar kinase PH14592.7.10.454
3p62FMNPentaerythritol tetranitrate reductase/0.454
3v94WYQPhosphodiesterase/0.454
4bfpSWYTankyrase-22.4.2.300.454
4iah1DXAlr2278 protein/0.454
4jqeANPCasein kinase II subunit alpha2.7.11.10.454
4jqh1MFAlr2278 protein/0.454
4xumIMNPeroxisome proliferator-activated receptor gamma/0.454
5k2bZMAAdenosine receptor A2a/0.454
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
1rdtL79Retinoic acid receptor RXR-alpha/0.453
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.453
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.453
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.453
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.453
2vbpVB1Isopenicillin N synthase1.21.3.10.453
2vnhFADNADPH:ferredoxin reductase/0.453
2w4qCBWProstaglandin reductase 21.3.1.480.453
2wleCOAPolysialic acid O-acetyltransferase/0.453
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.453
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.453
3c1xCKKHepatocyte growth factor receptor2.7.10.10.453
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.453
3ddw055Glycogen phosphorylase, liver form2.4.1.10.453
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3p99LNPLanosterol 14-alpha-demethylase/0.453
3vt9YI4Vitamin D3 receptor/0.453
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.453
4b4vL34Bifunctional protein FolD/0.453
4bfsZVSPantothenate kinase2.7.1.330.453
4bfvZVVPantothenate kinase2.7.1.330.453
4c02TAKActivin receptor type-12.7.11.300.453
4cdmFO1Deoxyribodipyrimidine photolyase/0.453
4g090VDHistidinol dehydrogenase/0.453
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.453
4jq7KJQEpidermal growth factor receptor2.7.10.10.453
4jr3KJREpidermal growth factor receptor2.7.10.10.453
4o0sADNAurora kinase A2.7.11.10.453
4p6wMOFGlucocorticoid receptor/0.453
4q71FADBifunctional protein PutA/0.453
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.453
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.452
1h1s4SPCyclin-dependent kinase 22.7.11.220.452
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1k74544Peroxisome proliferator-activated receptor gamma/0.452
1nzyBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.452
1p0fNAPNADP-dependent alcohol dehydrogenase1.1.1.20.452
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.452
2bbqPFGThymidylate synthase/0.452
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.452
2pvmP29Casein kinase II subunit alpha2.7.11.10.452
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.452
2xaaNADSecondary alcohol dehydrogenase/0.452
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.452
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.452
3c3xNAPEugenol synthase 11.1.1.3180.452
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.452
3dogNNNCyclin-dependent kinase 22.7.11.220.452
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3ha7B32Hydroxymycolate synthase MmaA42.1.10.452
3kpkFADSulfide-quinone reductase/0.452
3l8p0CEAngiopoietin-1 receptor2.7.10.10.452
3mcyZH1FimH/0.452
3otwCOAPhosphopantetheine adenylyltransferase/0.452
3owj1ELCasein kinase II subunit alpha2.7.11.10.452
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.452
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.452
4aotGW8Serine/threonine-protein kinase 102.7.11.10.452
4egnTWOCytochrome P450/0.452
4f640S8Fibroblast growth factor receptor 1/0.452
4fgrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.452
4i22IREEpidermal growth factor receptor2.7.10.10.452
4ia1BIVVitamin D3 receptor A/0.452
4jia1K3Tyrosine-protein kinase JAK2/0.452
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.452
4nmdFDABifunctional protein PutA/0.452
4xivACPChemotaxis protein CheA2.7.13.30.452
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1ep4S11Gag-Pol polyprotein2.7.7.490.451
1ke6LS2Cyclin-dependent kinase 22.7.11.220.451
1oiuN76Cyclin-dependent kinase 22.7.11.220.451
1vyrFMNPentaerythritol tetranitrate reductase/0.451
1ykdCMPAdenylate cyclase/0.451
1zhwHC2Oxysterol-binding protein homolog 4/0.451
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.451
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.451
2jlbUDMUncharacterized protein/0.451
2om9AJAPeroxisome proliferator-activated receptor gamma/0.451
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.451
3bc3OPTCathepsin L13.4.22.150.451
3f63GTXGlutathione transferase GST1-4/0.451
3fp0FP015-O-acetyltransferase/0.451
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.451
3nga3NGCasein kinase II subunit alpha2.7.11.10.451
3oqkS52Renin3.4.23.150.451
3p6nDSOCamphor 5-monooxygenase1.14.15.10.451
3sm2478Putative gag-pro-pol polyprotein/0.451
3uleC69Actin-related protein 3/0.451
3w0jT08Vitamin D3 receptor/0.451
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.451
4cukNAID-lactate dehydrogenase/0.451
4eevL1XHepatocyte growth factor receptor2.7.10.10.451
4fdpFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.451
4i8vBHFCytochrome P450 1A11.14.14.10.451
4v2gITCTetracycline repressor protein class D/0.451
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.450
1kzjCB3Thymidylate synthase/0.450
1r2jFADFkbI/0.450
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.450
2cchATPCyclin-dependent kinase 22.7.11.220.450
2hb8MVDVitamin D3 receptor/0.450
2i40BLZCyclin-dependent kinase 22.7.11.220.450
2o7oDXTTetracycline repressor protein class D/0.450
2tscCB3Thymidylate synthase/0.450
2vd5BI8Myotonin-protein kinase2.7.11.10.450
2xveFADPutative flavin-containing monooxygenase/0.450
2y6fM9FIsopenicillin N synthase1.21.3.10.450
2ym1FADPhenylacetone monooxygenase1.14.13.920.450
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.450
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.450
3bqdDAYGlucocorticoid receptor/0.450
3gcoVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.450
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.450
3hllI45Mitogen-activated protein kinase 14/0.450
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.450
3p74FMNPentaerythritol tetranitrate reductase/0.450
3q9oNADCholix toxin2.4.2.360.450
3tk3CPZCytochrome P450 2B41.14.14.10.450
3vt7VDXVitamin D3 receptor/0.450
4at0FADPossible succinate dehydrogenase/0.450
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.450
4jbtASDCytochrome P450 monooxygenase/0.450
4klaCHDFerrochelatase, mitochondrial4.99.1.10.450
4qe6JN3Bile acid receptor/0.450
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.450
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.450
5cvhADPCasein kinase II subunit alpha2.7.11.10.450
1bk0ACVIsopenicillin N synthase1.21.3.10.449
1blzACVIsopenicillin N synthase1.21.3.10.449
1tduCB3Thymidylate synthase/0.449
1uzwCDHIsopenicillin N synthase1.21.3.10.449
1ysx4EBSerum albumin/0.449
2am22LGUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.449
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.449
2dw4FADLysine-specific histone demethylase 1A10.449
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.449
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2izsBRQCasein kinase I isoform gamma-32.7.11.10.449
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.449
2p2jPRXAcetyl-coenzyme A synthetase/0.449
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.449
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2xvw9NRSerum albumin/0.449
2y37A54Nitric oxide synthase, inducible1.14.13.390.449
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
3fr5I4AFatty acid-binding protein, adipocyte/0.449
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.449
3mdmFJZCholesterol 24-hydroxylase/0.449
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.449
3p6pA6BCamphor 5-monooxygenase1.14.15.10.449
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.449
3s4qNK0Mitogen-activated protein kinase 14/0.449
3sruQ26Dihydrofolate reductase1.5.1.30.449
3tucFPWTyrosine-protein kinase SYK2.7.10.20.449
3u9y09LTankyrase-22.4.2.300.449
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.449
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.449
4g2h0VQVitamin D3 receptor A/0.449
4ia3BIVVitamin D3 receptor A/0.449
4mihFADPyranose 2-oxidase1.1.3.100.449
4pnmNU1Tankyrase-22.4.2.300.449
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.449
4qmzB49Serine/threonine-protein kinase 242.7.11.10.449
5ahsCOAAcyl-CoA dehydrogenase/0.449
5dozNDPJamJ/0.449
1fvt106Cyclin-dependent kinase 22.7.11.220.448
1jpaANPEphrin type-B receptor 22.7.10.10.448
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1qvnFRIInterleukin-2/0.448
1s6qTPBGag-Pol polyprotein2.7.7.490.448
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.448
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.448
2ed3SAHDiphthine synthase/0.448
2jn3JN3Fatty acid-binding protein, liver/0.448
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.448
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.448
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.448
2vx17X8Ephrin type-B receptor 42.7.10.10.448
2xk730ESerine/threonine-protein kinase Nek22.7.11.10.448
2y60M8FIsopenicillin N synthase1.21.3.10.448
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.448
3ad9NADSubunit alpha of sarocosine oxidase/0.448
3elm24FCollagenase 33.4.240.448
3g0fB49Mast/stem cell growth factor receptor Kit2.7.10.10.448
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.448
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.448
3rk909ZCyclin-dependent kinase 22.7.11.220.448
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.448
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.448
3v3vMYUMitogen-activated protein kinase 82.7.11.240.448
4a8v2ANMajor pollen allergen Bet v 1-J/0.448
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4f630S7Fibroblast growth factor receptor 1/0.448
4fv7E94Mitogen-activated protein kinase 12.7.11.240.448
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.448
4ib4ERM5-hydroxytryptamine receptor 2B/0.448
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.448
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.448
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.448
4x5jFOLDihydrofolate reductase1.5.1.30.448
4zgsNADPutative D-lactate dehydrogenase/0.448
5auuLU2Death-associated protein kinase 12.7.11.10.448
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.448
5dg3U21Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase/0.448
5e8xSTUTGF-beta receptor type-12.7.11.300.448
3uzaT4GAdenosine receptor A2a/0.448
1f4fTP3Thymidylate synthase/0.447
1ha3MAUElongation factor Tu-A/0.447
1ot7IU5Bile acid receptor/0.447
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.447
1q23FUAChloramphenicol acetyltransferase2.3.1.280.447
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.447
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.447
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.447
2wgjVGHHepatocyte growth factor receptor2.7.10.10.447
2yn8STUEphrin type-B receptor 42.7.10.10.447
3be9P04Casein kinase II subunit alpha2.7.11.10.447
3fktSIIBeta-secretase 13.4.23.460.447
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.447
3kpzZNEVitamin D3 receptor/0.447
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.447
3nfrEWQRibosyldihydronicotinamide dehydrogenase [quinone]/0.447
3nksACJProtoporphyrinogen oxidase1.3.3.40.447
3s79ASDAromatase1.14.14.140.447
3t3q9PLCytochrome P450 2A61.14.130.447
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.447
3zep1NXTyrosine-protein kinase JAK32.7.10.20.447
4dru0LNGenome polyprotein2.7.7.480.447
4fehFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.447
4fhh0U3Vitamin D3 receptor A/0.447
4fx360KCyclin-dependent kinase 22.7.11.220.447
4grb0XGCasein kinase II subunit alpha2.7.11.10.447
4jjiNADAlcohol dehydrogenase class-3/0.447
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.447
4ocvANPAminoglycoside phosphotransferase/0.447
5dt4ATPAurora kinase A2.7.11.10.447
1db1VDXVitamin D3 receptor/0.446
1fm69CRRetinoic acid receptor RXR-alpha/0.446
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.446
1fvv107Cyclin-dependent kinase 22.7.11.220.446
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1jujLYAThymidylate synthase2.1.1.450.446
1pjcNADAlanine dehydrogenase/0.446
1rkhVD2Vitamin D3 receptor/0.446
1szcCNANAD-dependent protein deacetylase HST23.5.10.446
1y4lSVRBasic phospholipase A2 homolog 2/0.446
2abbFMNPentaerythritol tetranitrate reductase/0.446
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.446
2b03TUDPhospholipase A2, major isoenzyme3.1.1.40.446
2hk9NAPShikimate dehydrogenase (NADP(+))/0.446
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.446
2z3uCRRCytochrome P450/0.446
2zdt46CMitogen-activated protein kinase 102.7.11.240.446
3anmSYD1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.446
3btjDEQHTH-type transcriptional regulator QacR/0.446
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.446
3gc8B45Mitogen-activated protein kinase 112.7.11.240.446
3h06VBPGlutamate receptor 2/0.446
3h3sH15Collagen type IV alpha-3-binding protein/0.446
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
3p67FMNPentaerythritol tetranitrate reductase/0.446
3ua506XCytochrome P450 2B61.14.130.446
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
3wleNAD(R)-specific carbonyl reductase/0.446
3zuyTCHTransporter/0.446
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.446
4em9TCEPeroxisome proliferator-activated receptor gamma/0.446
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4o71CPBBromodomain-containing protein 4/0.446
4qa1B3NHistone deacetylase 83.5.1.980.446
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.446
5dn3ATPAurora kinase A2.7.11.10.446
5iua6DXAdenosine receptor A2a/0.446
1di8DTQCyclin-dependent kinase 22.7.11.220.445
1diuBDMDihydrofolate reductase1.5.1.30.445
1fwkADPHomoserine kinase2.7.1.390.445
1gih1PUCyclin-dependent kinase 22.7.11.220.445
1ie8KH1Vitamin D3 receptor/0.445
1jstATPCyclin-dependent kinase 22.7.11.220.445
1m9jCLWNitric oxide synthase, endothelial1.14.13.390.445
1mq4ADPAurora kinase A2.7.11.10.445
1oi9N20Cyclin-dependent kinase 22.7.11.220.445
1ol5ADPAurora kinase A2.7.11.10.445
1rm4NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.445
1t2cNAIL-lactate dehydrogenase1.1.1.270.445
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2bgiFADNADPH:ferredoxin reductase/0.445
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.445
2fonFADAcyl-coenzyme A oxidase/0.445
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.445
2itpAEEEpidermal growth factor receptor2.7.10.10.445
2ittAEEEpidermal growth factor receptor2.7.10.10.445
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.445
2q7vFADThioredoxin reductase/0.445
2tohHBITyrosine 3-monooxygenase1.14.16.20.445
2uxxFAJLysine-specific histone demethylase 1A10.445
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.445
2zb3NDPProstaglandin reductase 21.3.1.480.445
2zbaZBATrichothecene 3-O-acetyltransferase/0.445
3glmCOOGlutaconyl-CoA decarboxylase alpha subunit/0.445
3issEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.445
3pm1ETHTH-type transcriptional regulator QacR/0.445
3r9hZ67Cyclin-dependent kinase 22.7.11.220.445
3rni21ZCyclin-dependent kinase 22.7.11.220.445
3tdl11DSerum albumin/0.445
3tmz06XCytochrome P450 2B41.14.14.10.445
3uhmRFNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.445
4asg814ATP-dependent molecular chaperone HSP82/0.445
4b3aTACTetracycline repressor protein class D/0.445
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.445
4h6pFMNChromate reductase/0.445
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.445
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.445
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4q72FADBifunctional protein PutA/0.445
5k2cZMAAdenosine receptor A2a/0.445
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1nhz486Glucocorticoid receptor/0.444
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.444
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.444
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2chlDKICasein kinase I isoform gamma-32.7.11.10.444
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.444
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.444
2o7pNAPRiboflavin biosynthesis protein RibD/0.444
2x1nX1NCyclin-dependent kinase 22.7.11.220.444
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.444
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.444
3bheBZNGag-Pol polyprotein3.4.23.160.444
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.444
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3l8sBFFMitogen-activated protein kinase 14/0.444
3mqe416Prostaglandin G/H synthase 21.14.99.10.444
3mtlFEFCyclin-dependent kinase 162.7.11.220.444
3p84FMNPentaerythritol tetranitrate reductase/0.444
3q9xEMOCasein kinase II subunit alpha2.7.11.10.444
3slz3TLPutative gag-pro-pol polyprotein/0.444
3tfq07MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.444
3vf9477Tyrosine-protein kinase SYK2.7.10.20.444
3vt8YI3Vitamin D3 receptor/0.444
3zkyWT4Isopenicillin N synthase1.21.3.10.444
4auxXTCTetracycline repressor protein class D/0.444
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.444
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.444
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.444
4gg70J8Hepatocyte growth factor receptor2.7.10.10.444
4isg1FYGlucokinase2.7.1.20.444
4ix4ADPUncharacterized protein/0.444
4jbqVX6Aurora kinase A2.7.11.10.444
4pkl1GHUncharacterized protein/0.444
4qjqOTRLactoperoxidase/0.444
3qakUKAAdenosine receptor A2a/0.444
1cbqRE9Cellular retinoic acid-binding protein 2/0.443
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1e3eNAIAlcohol dehydrogenase 41.1.1.10.443
1hpzAAPGag-Pol polyprotein2.7.7.490.443
1ke7LS3Cyclin-dependent kinase 22.7.11.220.443
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.443
2cig1DGDihydrofolate reductase1.5.1.30.443
2ignFADPyranose 2-oxidase/0.443
2m56CAMCamphor 5-monooxygenase1.14.15.10.443
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.443
2vqoTFGHistone deacetylase 43.5.1.980.443
2vwz7X6Ephrin type-B receptor 42.7.10.10.443
2ydfIO3Serum albumin/0.443
2zbzVDXVitamin D3 dihydroxylase/0.443
3a783EVVitamin D3 receptor/0.443
3coy53HPantothenate synthetase6.3.2.10.443
3fwjCAMCamphor 5-monooxygenase1.14.15.10.443
3gw9VNILanosterol 14-alpha-demethylase/0.443
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.443
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3iw7IPKMitogen-activated protein kinase 14/0.443
3med65BGag-Pol polyprotein2.7.7.490.443
3mjeNDPAmphB/0.443
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.443
3qu0X40Cyclin-dependent kinase 22.7.11.220.443
3zewSTUEphrin type-B receptor 42.7.10.10.443
4eomATPCyclin-dependent kinase 22.7.11.220.443
4fgj1PQRibosyldihydronicotinamide dehydrogenase [quinone]/0.443
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.443
4iteTEYVitamin D3 receptor/0.443
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.443
4rupH97Vitamin D3 receptor A/0.443
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.443
5iu4ZMAAdenosine receptor A2a/0.443
5k2aZMAAdenosine receptor A2a/0.443
1k6tXN1Gag-Pol polyprotein3.4.23.160.442
1rm5NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.442
2c3qGTXGlutathione S-transferase theta-12.5.1.180.442
2ejzSAHDiphthine synthase/0.442
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.442
2fzeAPRAlcohol dehydrogenase class-31.1.1.10.442
2ghlLIBMitogen-activated protein kinase 14/0.442
2iutAGSDNA translocase FtsK/0.442
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.442
2j9lATPH(+)/Cl(-) exchange transporter 5/0.442
2pvnP63Casein kinase II subunit alpha2.7.11.10.442
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.442
2xikJ60Serine/threonine-protein kinase 252.7.11.10.442
2xviFADPutative flavin-containing monooxygenase/0.442
3cntFADPolyamine oxidase FMS1/0.442
3falREARetinoic acid receptor RXR-alpha/0.442
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.442
3k7tFAD6-hydroxy-L-nicotine oxidase/0.442
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.442
3mb601ICasein kinase II subunit alpha2.7.11.10.442
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.442
3nhkVAPRibosyldihydronicotinamide dehydrogenase [quinone]/0.442
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.442
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.442
3vrwYS5Vitamin D3 receptor/0.442
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.442
4ac0MIYTetracycline repressor protein class B from transposon Tn10/0.442
4aguD15Cyclin-dependent kinase-like 1/0.442
4bcpT3CCyclin-dependent kinase 22.7.11.220.442
4bfuZVUPantothenate kinase2.7.1.330.442
4dcaADPAminoglycoside phosphotransferase/0.442
4en4ATPPyridoxal kinase2.7.1.350.442
4f650S9Fibroblast growth factor receptor 1/0.442
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.442
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.442
4ia7BIVVitamin D3 receptor A/0.442
4iae1DXAlr2278 protein/0.442
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.442
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.442
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.442
5jscFADPutative acyl-CoA dehydrogenase/0.442
1db48INPhospholipase A2, membrane associated/0.441
1e9hINRCyclin-dependent kinase 22.7.11.220.441
1ezfIN0Squalene synthase2.5.1.210.441
1kt3RTLRetinol-binding protein 4/0.441
1m52P17Tyrosine-protein kinase ABL12.7.10.20.441
1trgCB3Thymidylate synthase/0.441
1zgaHMKIsoflavone 4'-O-methyltransferase/0.441
2e9dB76Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.441
2gjnFMNNitronate monooxygenase1.13.12.160.441
2j0m4STFocal adhesion kinase 12.7.10.20.441
2jkkBI9Focal adhesion kinase 12.7.10.20.441
2kceD16Thymidylate synthase/0.441
2pmdGNPTranslation initiation factor 2 subunit gamma/0.441
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.441
2rhrEMOPutative ketoacyl reductase1.3.10.441
2rl2UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
2rlcCHDCholoylglycine hydrolase3.5.1.240.441
2rqfJH3Hemolymph juvenile hormone binding protein/0.441
2vf0F89Thymidylate synthase/0.441
2vwy7X5Ephrin type-B receptor 42.7.10.10.441
2x9dITCTetracycline repressor protein class D/0.441
3ac2KSETyrosine-protein kinase Lck2.7.10.20.441
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.441
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
3bzuA21Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.441
3cth319Hepatocyte growth factor receptor2.7.10.10.441
3ezpB3NHistone deacetylase 83.5.1.980.441
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.441
3mtfA3FActivin receptor type-12.7.11.300.441
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3r0tFU9Casein kinase II subunit alpha2.7.11.10.441
4a9e3PFBromodomain-containing protein 2/0.441
4ap1NAPSteroid monooxygenase/0.441
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4c3yFAD3-ketosteroid dehydrogenase/0.441
4esoNAPPutative oxidoreductase/0.441
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.441
4ia2BIVVitamin D3 receptor A/0.441
4j6bPLOCytochrome P450 monooxygenase/0.441
4lxhC1EAlpha/beta hydrolase fold/0.441
4mubOAQSulfotransferase oxamniquine resistance protein/0.441
4nk92K5Fibroblast growth factor receptor 1/0.441
4nks2M2Fibroblast growth factor receptor 1/0.441
4qa2SHHHistone deacetylase 83.5.1.980.441
4utdACPAurora kinase A2.7.11.10.441
5c1mCLRMu-type opioid receptor/0.441
5cb3APRO-acetyl-ADP-ribose deacetylase/0.441
5k2dZMAAdenosine receptor A2a/0.441
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.440
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.440
1pjkANPCasein kinase II subunit alpha2.7.11.10.440
1u54ACPActivated CDC42 kinase 1/0.440
2aclREARetinoic acid receptor RXR-alpha/0.440
2btrU73Cyclin-dependent kinase 22.7.11.220.440
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
2dvlFADAcyl-CoA dehydrogenase/0.440
2hs0ATPPhosphoribosylformylglycinamidine synthase subunit PurL/0.440
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.440
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.440
2k62ITLFatty acid-binding protein, liver/0.440
2ovhAS0Progesterone receptor/0.440
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.440
3d1z017Gag-Pol polyprotein3.4.23.160.440
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3ezvEZVCyclin-dependent kinase 22.7.11.220.440
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3ih0ANPUncharacterized sugar kinase PH14592.7.10.440
3il1B5DGlutamate receptor 2/0.440
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.440
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.440
3tm0ANPAminoglycoside 3'-phosphotransferase2.7.1.950.440
4a2jAS0Progesterone receptor/0.440
4c3xFAD3-ketosteroid dehydrogenase/0.440
4e730NRMitogen-activated protein kinase 82.7.11.240.440
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.440
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.440
4kbyC2EStimulator of interferon genes protein/0.440
4nc3ERM5-hydroxytryptamine receptor 2B/0.440
4q73FADBifunctional protein PutA/0.440
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.440
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.440
4zasTYDCalS13/0.440
5iubCLRAdenosine receptor A2a/0.440