sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3aqa | BYH | Bromodomain-containing protein 2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3aqa | BYH | Bromodomain-containing protein 2 | / | 1.000 | |
| 4bjx | 73B | Bromodomain-containing protein 4 | / | 0.664 | |
| 4c67 | L5S | Bromodomain-containing protein 4 | / | 0.651 | |
| 4c66 | H4C | Bromodomain-containing protein 4 | / | 0.650 | |
| 4ogi | R78 | Bromodomain-containing protein 4 | / | 0.649 | |
| 4a9n | A9N | Bromodomain-containing protein 2 | / | 0.630 | |
| 4bw1 | S5B | Bromodomain-containing protein 4 | / | 0.630 | |
| 4mr4 | 1K0 | Bromodomain-containing protein 4 | / | 0.622 | |
| 4a9o | A9O | Bromodomain-containing protein 2 | / | 0.620 | |
| 4hxs | 1A3 | Bromodomain-containing protein 4 | / | 0.619 | |
| 4a9l | P9L | Bromodomain-containing protein 4 | / | 0.617 | |
| 4nqm | Y1Z | Bromodomain-containing protein 4 | / | 0.614 | |
| 4hxr | 1A4 | Bromodomain-containing protein 4 | / | 0.612 | |
| 3zyu | 1GH | Bromodomain-containing protein 4 | / | 0.611 | |
| 4men | 25K | Bromodomain-containing protein 4 | / | 0.611 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.611 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.609 | |
| 2yel | WSH | Bromodomain-containing protein 4 | / | 0.603 | |
| 4bw3 | 9BM | Bromodomain-containing protein 4 | / | 0.602 | |
| 4j0s | 1H3 | Bromodomain-containing protein 4 | / | 0.599 | |
| 4hxn | 1A7 | Bromodomain-containing protein 4 | / | 0.598 | |
| 4lrg | 1XB | Bromodomain-containing protein 4 | / | 0.597 | |
| 4mep | 24Y | Bromodomain-containing protein 4 | / | 0.596 | |
| 4o74 | R78 | Bromodomain-containing protein 4 | / | 0.596 | |
| 4j0r | 1H2 | Bromodomain-containing protein 4 | / | 0.595 | |
| 4flp | JQ1 | Bromodomain testis-specific protein | / | 0.594 | |
| 4uyg | 73B | Bromodomain-containing protein 2 | / | 0.593 | |
| 4hby | 13F | Bromodomain-containing protein 4 | / | 0.592 | |
| 4lyw | 21Q | Bromodomain-containing protein 4 | / | 0.591 | |
| 4qzs | JQ1 | Bromodomain-containing protein 4 | / | 0.591 | |
| 4bw2 | UTH | Bromodomain-containing protein 4 | / | 0.589 | |
| 4lr6 | 1XA | Bromodomain-containing protein 4 | / | 0.587 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.586 | |
| 4alg | 1GH | Bromodomain-containing protein 2 | / | 0.584 | |
| 4hxo | 1A6 | Bromodomain-containing protein 4 | / | 0.581 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.574 | |
| 5bt5 | 2LO | Bromodomain-containing protein 2 | / | 0.565 | |
| 4f3i | 0S6 | Bromodomain-containing protein 4 | / | 0.564 | |
| 4nr5 | 2LL | CREB-binding protein | / | 0.564 | |
| 4hbw | 14Z | Bromodomain-containing protein 4 | / | 0.558 | |
| 4j3i | 1K0 | Bromodomain-containing protein 4 | / | 0.554 | |
| 2yek | EAM | Bromodomain-containing protein 2 | / | 0.553 | |
| 4mr6 | 1K0 | Bromodomain-containing protein 2 | / | 0.549 | |
| 4cfl | 8DQ | Bromodomain-containing protein 4 | / | 0.547 | |
| 4meq | 25O | Bromodomain-containing protein 4 | / | 0.547 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.545 | |
| 2yem | WSH | Bromodomain-containing protein 4 | / | 0.544 | |
| 4gpj | 0Q1 | Bromodomain-containing protein 4 | / | 0.544 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.536 | |
| 4o78 | SAV | Bromodomain-containing protein 4 | / | 0.526 | |
| 4akn | S5B | Bromodomain-containing protein 2 | / | 0.522 | |
| 4mr5 | 1K0 | Bromodomain-containing protein 2 | / | 0.522 | |
| 4nyw | 2O3 | CREB-binding protein | / | 0.513 | |
| 4nr8 | 2LL | Bromodomain-containing protein 4 | / | 0.512 | |
| 4nyv | 15E | CREB-binding protein | / | 0.502 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.499 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.498 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.498 | |
| 4cfk | LY2 | Bromodomain-containing protein 4 | / | 0.498 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.496 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.494 | |
| 4nra | 2LW | Bromodomain adjacent to zinc finger domain protein 2B | / | 0.494 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.491 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.491 | |
| 4ir5 | IR5 | Bromodomain adjacent to zinc finger domain protein 2B | / | 0.490 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.489 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.488 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.488 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.485 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.484 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.483 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.483 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.482 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.482 | |
| 5dfc | EAM | Bromodomain-containing protein 2 | / | 0.482 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.481 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.481 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.480 | |
| 2vwy | 7X5 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.480 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.480 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.479 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.479 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.479 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.479 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.479 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.478 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.478 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.478 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.478 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.477 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.477 | |
| 2bun | FAD | AppA protein | / | 0.476 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.476 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.476 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.476 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 5f0a | 1FB | cGMP-dependent protein kinase, putative | / | 0.476 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.476 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.475 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.475 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.475 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.475 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.475 | |
| 4a33 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.475 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.475 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.475 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.474 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.474 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.474 | |
| 3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3zrb | ORC | Progesterone receptor | / | 0.474 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.473 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.473 | |
| 4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.473 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.472 | |
| 2pvk | P45 | Casein kinase II subunit alpha | 2.7.11.1 | 0.472 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.472 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.471 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.471 | |
| 1lev | CLI | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.471 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.471 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.471 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.471 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.471 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.471 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.471 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.470 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.470 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.470 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.470 | |
| 3vhu | SNL | Mineralocorticoid receptor | / | 0.470 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.470 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.470 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.470 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.470 | |
| 1e3k | R18 | Progesterone receptor | / | 0.469 | |
| 1u5r | ATP | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.469 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.469 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.469 | |
| 4nqn | Y1Z | Bromodomain-containing protein 9 | / | 0.469 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.468 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.468 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.468 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.468 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.468 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.468 | |
| 5k8b | PDG | 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase | / | 0.468 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.467 | |
| 2piw | DHT | Androgen receptor | / | 0.467 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.467 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.467 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.467 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.467 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.467 | |
| 4cjw | CBJ | Integrase | / | 0.467 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 4gfg | 0XF | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.467 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.467 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.467 | |
| 4oal | 245 | Cytokinin dehydrogenase 4 | / | 0.467 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.466 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.466 | |
| 2q7i | TES | Androgen receptor | / | 0.466 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.466 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.466 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.466 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.466 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3gb4 | D3M | DdmC | / | 0.465 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.465 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.464 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.464 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.464 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.464 | |
| 2q5o | PPY | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.464 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.464 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.464 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.464 | |
| 4twp | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.464 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.463 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.463 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.463 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.463 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.463 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.463 | |
| 4fk8 | FAD | Ferredoxin--NADP reductase | / | 0.463 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.462 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 2oz6 | CMP | Cyclic AMP receptor-like protein | / | 0.462 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.462 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.462 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.462 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.461 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.461 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.461 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.461 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.461 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.461 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.461 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.461 | |
| 4oau | ADP | 2-5A-dependent ribonuclease | 3.1.26 | 0.461 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.461 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.460 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1rev | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 1sn0 | T44 | Transthyretin | / | 0.460 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.460 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.460 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.460 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.460 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.460 | |
| 3wfg | WFG | Mineralocorticoid receptor | / | 0.460 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.460 | |
| 4l8u | 9AZ | Serum albumin | / | 0.460 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.460 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.459 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1tl1 | H18 | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.459 | |
| 1v1a | KDG | 2-dehydro-3-deoxygluconokinase | 2.7.1.45 | 0.459 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.459 | |
| 2bgi | FAD | NADPH:ferredoxin reductase | / | 0.459 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.459 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.459 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.459 | |
| 3myk | ANP | Myosin-2 heavy chain | / | 0.459 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.459 | |
| 4ax8 | ADP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.459 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.459 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.459 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.458 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.458 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.458 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.458 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.458 | |
| 3fyv | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.458 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.458 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.458 | |
| 3w0q | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.458 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.458 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.458 | |
| 4ful | 0VU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.458 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.458 | |
| 4hmb | PZZ | Phospholipase A2 VRV-PL-VIIIa | / | 0.458 | |
| 4py6 | R78 | Bromodomain protein, putative | / | 0.458 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.458 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.458 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.458 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.457 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.457 | |
| 2np8 | CC3 | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.457 | |
| 2pit | DHT | Androgen receptor | / | 0.457 | |
| 2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 2xvw | 9NR | Serum albumin | / | 0.457 | |
| 3fsu | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.457 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.457 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.457 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.457 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.457 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.456 | |
| 1ppj | ANY | Cytochrome b | / | 0.456 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.456 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.456 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.456 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.456 | |
| 2jfa | RAL | Estrogen receptor | / | 0.456 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.456 | |
| 2ydj | YDJ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.456 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.456 | |
| 3dol | GWI | Pol protein | / | 0.456 | |
| 3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3r7v | Z02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.456 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.456 | |
| 4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.456 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.456 | |
| 4lsl | 1YQ | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.456 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.456 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.456 | |
| 5d12 | G97 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.456 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.455 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.455 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.455 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.455 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 2pix | DHT | Androgen receptor | / | 0.455 | |
| 3b9l | AZZ | Serum albumin | / | 0.455 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.455 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.455 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.455 | |
| 4mlh | VO2 | Glucokinase | 2.7.1.2 | 0.455 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.455 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 5ca0 | ACP | Tubulin tyrosine ligase | / | 0.455 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.454 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1th6 | OIN | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.454 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2a3i | C0R | Mineralocorticoid receptor | / | 0.454 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.454 | |
| 2q5o | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.454 | |
| 2z6j | TUI | 2-nitropropane dioxygenase | / | 0.454 | |
| 3cse | N22 | Uncharacterized protein | / | 0.454 | |
| 3gb2 | G3B | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.454 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.454 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4a9e | 3PF | Bromodomain-containing protein 2 | / | 0.454 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.454 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.454 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.454 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.454 | |
| 4rw6 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.454 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.453 | |
| 2ab2 | SNL | Mineralocorticoid receptor | / | 0.453 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.453 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.453 | |
| 2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.453 | |
| 3c3e | FO1 | 2-phospho-L-lactate transferase | / | 0.453 | |
| 3f88 | 3HT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3iw4 | LW4 | Protein kinase C alpha type | 2.7.11.13 | 0.453 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.453 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.453 | |
| 3u4u | LNH | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.453 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.453 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.453 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.453 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.453 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.453 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.453 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.453 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.453 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1g4s | TPS | Thiamine-phosphate synthase | / | 0.452 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 1rt5 | UC2 | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.452 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2xvv | 9DN | Serum albumin | / | 0.452 | |
| 3r32 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.452 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.452 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.452 | |
| 4b7p | 9UN | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 4hxm | 1A8 | Bromodomain-containing protein 4 | / | 0.452 | |
| 4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.452 | |
| 4kb8 | 1QN | Casein kinase I isoform delta | 2.7.11.1 | 0.452 | |
| 4ko0 | JLJ | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.452 | |
| 4y0x | ADP | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.452 | |
| 5cyq | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 5kp2 | COA | 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 | / | 0.452 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.451 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.451 | |
| 1lik | ADN | Adenosine kinase | 2.7.1.20 | 0.451 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.451 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.451 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.451 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.451 | |
| 2ocf | EST | Estrogen receptor | / | 0.451 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2vg7 | NNI | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 2w8y | 486 | Progesterone receptor | / | 0.451 | |
| 2w9g | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2xne | ASH | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.451 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.451 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.451 | |
| 3fre | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.451 | |
| 3i0s | RT7 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 3qrt | X14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 3w55 | 1FM | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.451 | |
| 4b7t | CWT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 4ez3 | 0S0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.451 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.451 | |
| 4gfo | 0X2 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.451 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.451 | |
| 4gnc | ASO | Regucalcin | 3.1.1.17 | 0.451 | |
| 4r3a | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.451 | |
| 5csh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.450 | |
| 1dtp | APU | Diphtheria toxin | / | 0.450 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.450 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1nde | MON | Estrogen receptor beta | / | 0.450 | |
| 1qvn | FRI | Interleukin-2 | / | 0.450 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.450 | |
| 2uxi | G50 | HTH-type transcriptional regulator TtgR | / | 0.450 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.450 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 3rvg | 17P | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 3sfi | 3SF | HTH-type transcriptional regulator EthR | / | 0.450 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.450 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.450 | |
| 4btk | DTQ | Tau-tubulin kinase 1 | 2.7.11.1 | 0.450 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.450 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.450 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.450 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.450 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.450 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.450 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.450 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 4pzt | SOP | Histone acetyltransferase p300 | / | 0.450 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.450 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.449 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 1upa | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.449 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 2vos | ADP | Folylpolyglutamate synthase | / | 0.449 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.449 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.449 | |
| 3cy3 | JN5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 3eej | 53R | Uncharacterized protein | / | 0.449 | |
| 3fd6 | ADP | Selenide, water dikinase 1 | 2.7.9.3 | 0.449 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.449 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.449 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.449 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.449 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.449 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.449 | |
| 3wff | WFF | Mineralocorticoid receptor | / | 0.449 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.449 | |
| 4fl1 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.449 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.449 | |
| 4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.449 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4mf1 | 29Y | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.449 | |
| 4oae | CLM | Uncharacterized protein | / | 0.449 | |
| 1bif | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.448 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 1hni | AAA | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.448 | |
| 1ol6 | ATP | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 1q3e | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.448 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.448 | |
| 1rt4 | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.448 | |
| 2bxq | IMN | Serum albumin | / | 0.448 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.448 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.448 | |
| 2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.448 | |
| 2y5s | 78H | Dihydropteroate synthase | / | 0.448 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.448 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.448 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.448 | |
| 3mtl | FEF | Cyclin-dependent kinase 16 | 2.7.11.22 | 0.448 | |
| 3nfa | CBJ | Gag-Pol polyprotein | / | 0.448 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.448 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 3qqg | X06 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3up3 | XCA | aceDAF-12 | / | 0.448 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.448 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.448 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.448 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.448 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.448 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.448 | |
| 4ix5 | ANP | Uncharacterized protein | / | 0.448 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.447 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.447 | |
| 1s9p | DES | Estrogen-related receptor gamma | / | 0.447 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.447 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.447 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.447 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.447 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.447 | |
| 3nxe | 2NC | Protease | / | 0.447 | |
| 3ocs | 746 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.447 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.447 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.447 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.447 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.447 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.447 | |
| 5ikr | ID8 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.447 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.446 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.446 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 1t74 | DHT | Androgen receptor | / | 0.446 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 1xow | R18 | Androgen receptor | / | 0.446 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.446 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.446 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.446 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 2piv | DHT | Androgen receptor | / | 0.446 | |
| 2v1a | FMN | NPH1-1 | / | 0.446 | |
| 2ydx | STL | Methionine adenosyltransferase 2 subunit beta | / | 0.446 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.446 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.446 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.446 | |
| 3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3cly | ACP | Fibroblast growth factor receptor 2 | / | 0.446 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.446 | |
| 3jpv | 1DR | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.446 | |
| 3rnn | RNN | Glutamate receptor 2 | / | 0.446 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.446 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.446 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.446 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.446 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.446 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 4a95 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4fkp | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.446 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.446 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.446 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 5cu6 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 5dt4 | ATP | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.445 | |
| 1pxx | DIF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.445 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2l84 | J28 | CREB-binding protein | / | 0.445 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.445 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2vnj | FAD | NADPH:ferredoxin reductase | / | 0.445 | |
| 2x4f | 16X | Myosin light chain kinase family member 4 | 2.7.11.1 | 0.445 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.445 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.445 | |
| 3ez2 | ADP | Plasmid partition protein A | / | 0.445 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3gob | HXX | DdmC | / | 0.445 | |
| 3ih0 | ANP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.445 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 3k2h | LYA | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 3ls8 | AJZ | Phosphatidylinositol 3-kinase catalytic subunit type 3 | 2.7.1.137 | 0.445 | |
| 3q9y | TXQ | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3q9z | TXQ | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3r37 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.445 | |
| 3r6t | LU1 | Catechol O-methyltransferase | 2.1.1.6 | 0.445 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.445 | |
| 3w2s | W2R | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 4agu | D15 | Cyclin-dependent kinase-like 1 | / | 0.445 | |
| 4aoi | 4K0 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 4bmo | FMN | Protein NrdI | / | 0.445 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.445 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.445 | |
| 4l2y | XXK | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.445 | |
| 4pda | CTN | Nucleoside permease | / | 0.445 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.445 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.445 | |
| 1f28 | UMP | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.444 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.444 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.444 | |
| 1qiw | DPD | Calmodulin | / | 0.444 | |
| 1sn5 | T3 | Transthyretin | / | 0.444 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.444 | |
| 2ama | DHT | Androgen receptor | / | 0.444 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2ihv | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.444 | |
| 2q7k | TES | Androgen receptor | / | 0.444 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.444 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.444 | |
| 3ad6 | KSC | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.444 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.444 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.444 | |
| 3o99 | K13 | Pol polyprotein | / | 0.444 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.444 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.444 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.444 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.444 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.444 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.444 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 4gyi | ADP | Uncharacterized protein | / | 0.444 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.444 | |
| 4nbb | 9CA | Terminal oxygenase component of carbazole | / | 0.444 | |
| 4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.444 | |
| 4utd | ACP | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 5cb4 | ACP | Tubulin tyrosine ligase | / | 0.444 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 1jx0 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.443 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1t65 | DHT | Androgen receptor | / | 0.443 | |
| 1z69 | F42 | 5,10-methylenetetrahydromethanopterin reductase | / | 0.443 | |
| 2abi | 1CA | Mineralocorticoid receptor | / | 0.443 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.443 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 2pvr | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 2w8y | NDR | Progesterone receptor | / | 0.443 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 2x2m | X2M | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.443 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.443 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3dle | GFA | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.443 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.443 | |
| 3qly | 55V | Uncharacterized protein | / | 0.443 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.443 | |
| 3tnw | F18 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.443 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.443 | |
| 3zm4 | 22T | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.443 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.443 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4dca | ADP | Aminoglycoside phosphotransferase | / | 0.443 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 4eh7 | 0OO | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.443 | |
| 4fa6 | 0TA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.443 | |
| 4k9p | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.443 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.443 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.443 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.443 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1csc | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.442 | |
| 1fml | RTL | Retinol dehydratase | / | 0.442 | |
| 1gij | 2PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.442 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.442 | |
| 1osv | CHC | Bile acid receptor | / | 0.442 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.442 | |
| 1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.442 | |
| 1sxj | ADP | Replication factor C subunit 5 | / | 0.442 | |
| 2acw | UPG | Glycosyltransferase | / | 0.442 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.442 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.442 | |
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3mb7 | 14I | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.442 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.442 | |
| 3qwj | X6A | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3rep | ATP | Integrin-linked protein kinase | 2.7.11.1 | 0.442 | |
| 3rm7 | 19Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3wd7 | COA | Acridone synthase | / | 0.442 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.442 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.442 | |
| 4c73 | TLH | 3-oxoacyl-ACP synthase | / | 0.442 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.442 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.442 | |
| 4lyn | 1YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 4oth | DRN | Serine/threonine-protein kinase N1 | / | 0.442 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.442 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.442 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.442 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.442 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.442 | |
| 5c03 | AGS | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.442 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.442 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.441 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.441 | |
| 1hnv | TBO | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1ikw | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.441 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.441 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1t7m | DHT | Androgen receptor | / | 0.441 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2g97 | DGB | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.441 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.441 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.441 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.441 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.441 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3d90 | NOG | Progesterone receptor | / | 0.441 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.441 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3h1j | SMA | Cytochrome b | / | 0.441 | |
| 3i0r | RT3 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.441 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.441 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.441 | |
| 3ujl | A8S | Abscisic acid receptor PYL2 | / | 0.441 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.441 | |
| 4c3r | ACP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4e1z | 0MX | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.441 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.441 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.441 | |
| 4h0d | ZZ7 | Metallo-beta-lactamase type 2 | / | 0.441 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4k7a | DHT | Androgen receptor | / | 0.441 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.441 | |
| 4uya | AGS | Mitogen-activated protein kinase kinase kinase 21 | 2.7.11.25 | 0.441 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.441 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1c6z | ROC | Protease | / | 0.440 | |
| 1err | RAL | Estrogen receptor | / | 0.440 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.440 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.440 | |
| 1tl3 | H20 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1upb | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.440 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.440 | |
| 2aa2 | AS4 | Mineralocorticoid receptor | / | 0.440 | |
| 2aa5 | STR | Mineralocorticoid receptor | / | 0.440 | |
| 2be2 | R22 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.440 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.440 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.440 | |
| 3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.440 | |
| 3gu6 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.440 | |
| 3mee | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3pyy | 3YY | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 3qar | QAR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3t1a | 5MA | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 3uvp | 048 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3v5j | 0F2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.440 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.440 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 3zv5 | BPY | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.440 | |
| 4a4v | YFD | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4aoj | V4Z | High affinity nerve growth factor receptor | 2.7.10.1 | 0.440 | |
| 4apu | A2K | Progesterone receptor | / | 0.440 | |
| 4bgh | 3I6 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4egn | TWO | Cytochrome P450 | / | 0.440 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4fv4 | EK7 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4fyo | 0VF | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4gvj | ADP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.440 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.440 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4oav | ACP | 2-5A-dependent ribonuclease | 3.1.26 | 0.440 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 5c8y | ACP | Tubulin tyrosine ligase | / | 0.440 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 |