sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2srt | INH | Stromelysin-1 | 3.4.24.17 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2srt | INH | Stromelysin-1 | 3.4.24.17 | 1.000 | |
| 1g05 | BBH | Stromelysin-1 | 3.4.24.17 | 0.551 | |
| 1d7x | SPC | Stromelysin-1 | 3.4.24.17 | 0.540 | |
| 1g4k | HQQ | Stromelysin-1 | 3.4.24.17 | 0.538 | |
| 2woa | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.532 | |
| 3aig | 0ZC | Snake venom metalloproteinase adamalysin-2 | 3.4.24.46 | 0.532 | |
| 4i03 | L88 | Macrophage metalloelastase | 3.4.24.65 | 0.524 | |
| 1atl | 0QI | Snake venom metalloproteinase atrolysin-D | 3.4.24.42 | 0.523 | |
| 1bzs | BSI | Neutrophil collagenase | 3.4.24.34 | 0.520 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.517 | |
| 2ow0 | 6MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.514 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.512 | |
| 1rm8 | BAT | Matrix metalloproteinase-16 | 3.4.24 | 0.510 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.510 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.510 | |
| 1dth | BAT | Snake venom metalloproteinase atrolysin-D | 3.4.24.42 | 0.509 | |
| 1biw | S80 | Stromelysin-1 | 3.4.24.17 | 0.507 | |
| 2wo8 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.507 | |
| 2v0u | FMN | NPH1-1 | / | 0.505 | |
| 1b8y | IN7 | Stromelysin-1 | 3.4.24.17 | 0.503 | |
| 1jk3 | BAT | Macrophage metalloelastase | 3.4.24.65 | 0.502 | |
| 1you | PFD | Collagenase 3 | 3.4.24 | 0.501 | |
| 2xs3 | ALA_PHE_THR_SER | Karilysin | 3.4.24 | 0.500 | |
| 3tsk | QEG | Macrophage metalloelastase | 3.4.24.65 | 0.500 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.499 | |
| 3ayk | CGS | Interstitial collagenase | 3.4.24.7 | 0.499 | |
| 3u04 | BB2 | Peptide deformylase | / | 0.499 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.498 | |
| 1zvx | FIN | Neutrophil collagenase | 3.4.24.34 | 0.497 | |
| 1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.496 | |
| 2dw0 | GM6 | Zinc metalloproteinase-disintegrin-like VAP2B | 3.4.24 | 0.496 | |
| 2ddy | MDW | Matrilysin | 3.4.24.23 | 0.495 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.495 | |
| 1fls | WAY | Collagenase 3 | 3.4.24 | 0.494 | |
| 2xs4 | ALA_PHE_THR | Karilysin | 3.4.24 | 0.494 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.492 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.491 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.491 | |
| 3mje | NDP | AmphB | / | 0.490 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.490 | |
| 2jih | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | 3.4.24 | 0.489 | |
| 2ovz | 5MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.489 | |
| 2owu | SAH | Diphthine synthase | / | 0.489 | |
| 2w13 | WR2 | Snake venom metalloproteinase BaP1 | 3.4.24 | 0.489 | |
| 4ros | APR | Malate dehydrogenase | / | 0.489 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.488 | |
| 2w14 | WR2 | Snake venom metalloproteinase BaP1 | 3.4.24 | 0.487 | |
| 1gkc | NFH | Matrix metalloproteinase-9 | 3.4.24.35 | 0.486 | |
| 1zs0 | EIN | Neutrophil collagenase | 3.4.24.34 | 0.486 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.486 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.485 | |
| 1mnc | PLH | Neutrophil collagenase | 3.4.24.34 | 0.484 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.483 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.483 | |
| 2jsd | NGH | Matrix metalloproteinase-20 | 3.4.24 | 0.482 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.481 | |
| 1g28 | FMN | PHY3 | / | 0.481 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.481 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.481 | |
| 2oy2 | ILE_ALA_GLY | Neutrophil collagenase | 3.4.24.34 | 0.481 | |
| 3oho | Z79 | Stromelysin-1 | 3.4.24.17 | 0.481 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 3b92 | 440 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.480 | |
| 3eks | CY9 | Actin-5C | / | 0.480 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.480 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 2i47 | KGY | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.478 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.478 | |
| 3qge | 26F | Genome polyprotein | 2.7.7.48 | 0.478 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.477 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.477 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.477 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.476 | |
| 2dxv | SAH | Diphthine synthase | / | 0.476 | |
| 2e07 | SAH | Diphthine synthase | / | 0.476 | |
| 4ew3 | DXZ | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.476 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.475 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.475 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.475 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.475 | |
| 2wo9 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.475 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.475 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.474 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.474 | |
| 4lb2 | DM5 | Serum albumin | / | 0.474 | |
| 2dxw | SAH | Diphthine synthase | / | 0.473 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.473 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.473 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.472 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.472 | |
| 1hv5 | RXP | Stromelysin-3 | 3.4.24 | 0.472 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.472 | |
| 2a8h | 4NH | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.472 | |
| 2pda | TPP | Pyruvate synthase | / | 0.472 | |
| 2v1a | FMN | NPH1-1 | / | 0.472 | |
| 2zro | ADP | Protein RecA | / | 0.472 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.472 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.471 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.471 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.471 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3b9l | AZZ | Serum albumin | / | 0.470 | |
| 1m8g | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.469 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.469 | |
| 1zxc | IH6 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.469 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.469 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.468 | |
| 2zkj | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.468 | |
| 3u7l | UDB | Peptide deformylase | / | 0.468 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.468 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.467 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.467 | |
| 1l4f | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.467 | |
| 2emr | SAH | Diphthine synthase | / | 0.467 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.467 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.466 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.466 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.466 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.466 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.466 | |
| 3eku | CY9 | Actin-5C | / | 0.466 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.466 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.466 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.466 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.465 | |
| 1pwu | GM6 | Lethal factor | 3.4.24.83 | 0.465 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.465 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.465 | |
| 4guk | P2G | Neuronal calcium sensor 1 | / | 0.465 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.465 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.465 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.464 | |
| 2bxm | IMN | Serum albumin | / | 0.464 | |
| 2el0 | SAH | Diphthine synthase | / | 0.464 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.464 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.464 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.464 | |
| 4eep | FMN | Phototropin-2 | 2.7.11.1 | 0.464 | |
| 1fm1 | WAY | Collagenase 3 | 3.4.24 | 0.463 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 2hut | SAH | Diphthine synthase | / | 0.463 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.463 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.463 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.463 | |
| 4ayk | CGS | Interstitial collagenase | 3.4.24.7 | 0.463 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4l4x | NDP | AmphI | / | 0.463 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.462 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.462 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1l4m | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.462 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.462 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.462 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.462 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.462 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.462 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.462 | |
| 5c4c | UPG | Histo-blood group ABO system transferase | / | 0.462 | |
| 1f0y | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.461 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2huq | SAH | Diphthine synthase | / | 0.461 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.461 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.461 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.461 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.461 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.461 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.461 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.460 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.460 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.460 | |
| 2jnp | NGH | Stromelysin-1 | 3.4.24.17 | 0.460 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.460 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.460 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.460 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.460 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.460 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.460 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.460 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.460 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.459 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.459 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.459 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.459 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.459 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.459 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.459 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.459 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.459 | |
| 4b4g | KKT | Glucose-1-phosphate thymidylyltransferase | / | 0.459 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.459 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.459 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.459 | |
| 1d5j | MM3 | Stromelysin-1 | 3.4.24.17 | 0.458 | |
| 1l4k | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.458 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.458 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.458 | |
| 1ywn | LIF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.458 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.458 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.458 | |
| 2iyp | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.458 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.458 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.458 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.458 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.458 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.458 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.458 | |
| 5hgc | HCY | Uncharacterized protein | / | 0.458 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.457 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.457 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.457 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1z4u | PH9 | Polyprotein | / | 0.457 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2egs | SAH | Diphthine synthase | / | 0.457 | |
| 2vdg | NDP | Aldose reductase | 1.1.1.21 | 0.457 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.457 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.457 | |
| 3pn4 | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.457 | |
| 4e9b | BB2 | Peptide deformylase | / | 0.457 | |
| 4ew2 | DXY | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.457 | |
| 4hxy | NDP | Plm1 | / | 0.457 | |
| 1l4l | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.456 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.456 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.456 | |
| 2zre | AGS | Protein RecA | / | 0.456 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3rlp | 3RP | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 4hj6 | FMN | LOV protein | / | 0.456 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.456 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.456 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.455 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.455 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2bkj | FMN | NADPH-flavin oxidoreductase | / | 0.455 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.455 | |
| 2dsg | SAH | Diphthine synthase | / | 0.455 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.455 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.455 | |
| 2qfo | A13 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 2xvv | 9DN | Serum albumin | / | 0.455 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.455 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.455 | |
| 5efw | FMN | NPH1-1 | / | 0.455 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.454 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.454 | |
| 2cji | GSK | Coagulation factor X | 3.4.21.6 | 0.454 | |
| 2e8h | SAH | Diphthine synthase | / | 0.454 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.454 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.454 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 3evb | SAH | Genome polyprotein | 2.1.1.56 | 0.454 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.454 | |
| 4egi | B2J | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.454 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.454 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.454 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1pvg | ANP | DNA topoisomerase 2 | 5.99.1.3 | 0.453 | |
| 1q6y | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.453 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 2e08 | SAH | Diphthine synthase | / | 0.453 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.453 | |
| 2emu | SAH | Diphthine synthase | / | 0.453 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.453 | |
| 2yvg | NAD | Ferredoxin reductase | / | 0.453 | |
| 3e6y | CW1 | 14-3-3-like protein C | / | 0.453 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 4hia | FMN | LOV protein | / | 0.453 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.453 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 4umy | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.453 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.453 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.452 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.452 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.452 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.452 | |
| 2ahc | VNL | Chorismate pyruvate-lyase | / | 0.452 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.452 | |
| 2zrf | DTP | Protein RecA | / | 0.452 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.452 | |
| 4kgn | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.452 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.452 | |
| 5djt | FMN | NPH1-2 | / | 0.452 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1ix1 | BB2 | Peptide deformylase | / | 0.451 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.451 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.451 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.451 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.451 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.451 | |
| 1til | ATP | Anti-sigma F factor | / | 0.451 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.451 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.451 | |
| 2e16 | SAH | Diphthine synthase | / | 0.451 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.451 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.451 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.451 | |
| 2owv | SAH | Diphthine synthase | / | 0.451 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.451 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.451 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.451 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3rzp | PRF | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.451 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.451 | |
| 4j7u | YTZ | Sepiapterin reductase | 1.1.1.153 | 0.451 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.451 | |
| 1caq | DPS | Stromelysin-1 | 3.4.24.17 | 0.450 | |
| 1odx | 0E8 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1rp4 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.450 | |
| 2bxq | IMN | Serum albumin | / | 0.450 | |
| 2ejk | SAH | Diphthine synthase | / | 0.450 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.450 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 2vw5 | BC6 | ATP-dependent molecular chaperone HSP82 | / | 0.450 | |
| 2xb8 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.450 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.450 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.450 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3rqh | B6P | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.450 | |
| 3zcb | ATP | Adenosine monophosphate-protein transferase VbhT | 2.7.7.n1 | 0.450 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 4ih7 | 1ER | Genome polyprotein | 2.7.7.48 | 0.450 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.450 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.450 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.450 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.450 | |
| 1a80 | NDP | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.449 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.449 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.449 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.449 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2aie | SB9 | Peptide deformylase | / | 0.449 | |
| 2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.449 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.449 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.449 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.449 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 2z2d | HSI | Macrophage metalloelastase | 3.4.24.65 | 0.449 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.449 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.449 | |
| 4cgh | LOZ | Integrase | / | 0.449 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.449 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.449 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.449 | |
| 4rrj | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.449 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.449 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.449 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.448 | |
| 1nas | ASE | Sepiapterin reductase | 1.1.1.153 | 0.448 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.448 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.448 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.448 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.448 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.448 | |
| 2p5f | SAH | Diphthine synthase | / | 0.448 | |
| 2pd8 | FAD | Vivid PAS protein VVD | / | 0.448 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3kmc | 403 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.448 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.448 | |
| 3v2u | ATP | Protein GAL3 | / | 0.448 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.448 | |
| 4de5 | 0JD | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.448 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.448 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.447 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.447 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.447 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.447 | |
| 1mxi | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.447 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.447 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.447 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.447 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.447 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 3kds | NHX | ATP-dependent zinc metalloprotease FtsH | / | 0.447 | |
| 3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 4hhd | FMN | Phototropin-1 | 2.7.11.1 | 0.447 | |
| 4kuo | RBF | Putative blue-light photoreceptor | / | 0.447 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.446 | |
| 1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.446 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.446 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.446 | |
| 2egl | SAH | Diphthine synthase | / | 0.446 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.446 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.446 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.446 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.446 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.446 | |
| 4bn1 | ADP | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4ees | FMN | Phototropin-2 | 2.7.11.1 | 0.446 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.446 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.446 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.445 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.445 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.445 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.445 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.445 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.445 | |
| 2ol0 | DUD | DUTP pyrophosphatase | / | 0.445 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.445 | |
| 2xw1 | 9NV | Serum albumin | / | 0.445 | |
| 2zrj | AGS | Protein RecA | / | 0.445 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 3c23 | 3AT | DNA integrity scanning protein DisA | / | 0.445 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.445 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.445 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.445 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.445 | |
| 3gts | D3M | DdmC | / | 0.445 | |
| 3k8t | 2A5 | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.445 | |
| 3m6r | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.445 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.445 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.445 | |
| 3tb9 | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.445 | |
| 3u7k | MDB | Peptide deformylase | / | 0.445 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.445 | |
| 3zt1 | OM1 | Integrase | / | 0.445 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.445 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.445 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.445 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.445 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.445 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.445 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 1kol | NAD | Glutathione-independent formaldehyde dehydrogenase | / | 0.444 | |
| 2b8v | 3BN | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2dek | SAH | Diphthine synthase | / | 0.444 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.444 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.444 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.444 | |
| 2gfd | RDA | Endoplasmin | / | 0.444 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.444 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.444 | |
| 2j7p | GNP | Signal recognition particle protein | / | 0.444 | |
| 2j7p | GNP | Signal recognition particle receptor FtsY | / | 0.444 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.444 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.444 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.444 | |
| 3pcg | 4HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.444 | |
| 3pcg | 4HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.444 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.444 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3zuy | TCH | Transporter | / | 0.444 | |
| 4bmp | FMN | Protein NrdI | / | 0.444 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.444 | |
| 4fvq | ATP | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.444 | |
| 4jwf | SAH | tRNA (guanine(9)-N1)-methyltransferase | / | 0.444 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.444 | |
| 5a8a | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.444 | |
| 5i4n | ATP | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.443 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1ht2 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.443 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.443 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.443 | |
| 1w35 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.443 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.443 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.443 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.443 | |
| 2eft | COA | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.443 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.443 | |
| 3co9 | 3MS | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3cvk | N34 | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.443 | |
| 3t50 | FMN | Blue-light-activated histidine kinase | 2.7.13.3 | 0.443 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.443 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.443 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.443 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.443 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.443 | |
| 5a3b | APR | SIR2 family protein | / | 0.443 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.442 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.442 | |
| 1cx2 | S58 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.442 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.442 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.442 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.442 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.442 | |
| 1z45 | UPG | Bifunctional protein GAL10 | 5.1.3.2 | 0.442 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.442 | |
| 2hux | SAH | Diphthine synthase | / | 0.442 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.442 | |
| 2owg | SAH | Diphthine synthase | / | 0.442 | |
| 2pch | SAH | Diphthine synthase | / | 0.442 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.442 | |
| 2r3a | SAM | Histone-lysine N-methyltransferase SUV39H2 | 2.1.1.43 | 0.442 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2z6c | FMN | Phototropin-1 | 2.7.11.1 | 0.442 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.442 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.442 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.442 | |
| 3cwj | 321 | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.442 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.442 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.442 | |
| 4cgi | NZL | Integrase | / | 0.442 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.442 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.442 | |
| 4uxq | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.442 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.442 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.442 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.442 | |
| 4z87 | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.442 | |
| 5a3c | NAD | SIR2 family protein | / | 0.442 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.442 | |
| 1fnn | ADP | ORC1-type DNA replication protein | / | 0.441 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.441 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.441 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
| 1sxj | AGS | Replication factor C subunit 1 | / | 0.441 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.441 | |
| 2d81 | RB3 | Poly(3-hydroxybutyrate) depolymerase | / | 0.441 | |
| 2eck | ADP | Adenylate kinase | / | 0.441 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.441 | |
| 3ae4 | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.441 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.441 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.441 | |
| 3fpk | FAD | Ferredoxin-NADP reductase | / | 0.441 | |
| 3gag | FMN | Putative NADH dehydrogenase NAD(P)H nitroreductase | / | 0.441 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.441 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.441 | |
| 3vaq | ADN | Putative adenosine kinase | / | 0.441 | |
| 3w3o | ROE | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.441 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 3zv6 | 4HB | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.441 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4egn | TWO | Cytochrome P450 | / | 0.441 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4rcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.441 | |
| 4xbo | SAH | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.1.1.200 | 0.441 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.441 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.440 | |
| 1m8j | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.440 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1ozv | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.440 | |
| 1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.440 | |
| 1sxj | ADP | Replication factor C subunit 5 | / | 0.440 | |
| 1szj | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.440 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1vce | SAH | Diphthine synthase | / | 0.440 | |
| 1wng | SAH | Diphthine synthase | / | 0.440 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.440 | |
| 2c3p | 1TP | Pyruvate synthase | / | 0.440 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.440 | |
| 2e8r | SAH | Diphthine synthase | / | 0.440 | |
| 2o1v | ADP | Endoplasmin | / | 0.440 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.440 | |
| 2r26 | CMC | Citrate synthase | 2.3.3.16 | 0.440 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.440 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.440 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.440 | |
| 3koq | FMN | Putative nitroreductase | / | 0.440 | |
| 3lxp | IZA | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.440 | |
| 3tw6 | ADP | Pyruvate carboxylase | / | 0.440 | |
| 3uaw | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.440 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4buv | 16I | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4eox | 0S5 | Peptide deformylase | / | 0.440 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.440 | |
| 4kwh | NAP | Reductase homolog | / | 0.440 | |
| 4lvg | 20O | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.440 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 5dkk | FMN | Predicted protein | / | 0.440 |