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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4rrdA3TProbable threonine--tRNA ligase 26.1.1.3

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4rrdA3TProbable threonine--tRNA ligase 26.1.1.31.000
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.709
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.697
4rrbA3TProbable threonine--tRNA ligase 26.1.1.30.635
4rrlA3SProbable threonine--tRNA ligase 26.1.1.30.614
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.605
4rr9A3SProbable threonine--tRNA ligase 26.1.1.30.600
4rrcA3TProbable threonine--tRNA ligase 26.1.1.30.600
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.594
4rr8A3SProbable threonine--tRNA ligase 26.1.1.30.587
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.583
4rrrA3TThreonine--tRNA ligase6.1.1.30.582
4rrjA3SProbable threonine--tRNA ligase 26.1.1.30.572
4rrgA3TThreonine--tRNA ligase6.1.1.30.558
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.552
3pd3A3TThreonine--tRNA ligase6.1.1.30.538
4rrfA3SThreonine--tRNA ligase6.1.1.30.535
4rrkA3TProbable threonine--tRNA ligase 26.1.1.30.533
2hl0A3SThreonine--tRNA ligase6.1.1.30.531
3pd2A3SThreonine--tRNA ligase6.1.1.30.526
3pd4A3GThreonine--tRNA ligase6.1.1.30.524
3h3t16HCollagen type IV alpha-3-binding protein/0.519
2hl1A3SThreonine--tRNA ligase6.1.1.30.512
2lbaCHOFatty acid binding protein 6/0.512
2e0nSAHPrecorrin-2 C20-methyltransferase/0.505
3h3r14HCollagen type IV alpha-3-binding protein/0.504
4b2gV1NUncharacterized protein/0.503
2po7CHDFerrochelatase, mitochondrial4.99.1.10.500
4o2bLOCTubulin beta-2B chain/0.498
2hl2SSAThreonine--tRNA ligase6.1.1.30.497
4dc0NDPPutative ketoacyl reductase1.3.10.496
3junAKDPhenazine biosynthesis protein A/B/0.493
3v0p4GWHisto-blood group ABO system transferase/0.493
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.492
4ead0NPThymidine phosphorylase2.4.2.40.492
4iteTEYVitamin D3 receptor/0.491
4rrqA3SThreonine--tRNA ligase6.1.1.30.489
4yekTHMThymidine phosphorylase/0.489
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.488
4nieNBHNuclear receptor ROR-gamma/0.488
4xwtU5PRibonuclease J/0.488
3w0aDS5Vitamin D3 receptor/0.487
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.487
1zgaHMKIsoflavone 4'-O-methyltransferase/0.485
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.485
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.485
3w0yDS4Vitamin D3 receptor/0.485
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.485
4qzuRTLRetinol-binding protein 2/0.485
1fm4DXCMajor pollen allergen Bet v 1-L/0.484
2cy0NAPShikimate dehydrogenase (NADP(+))/0.483
3i0pNADMalate dehydrogenase, putative/0.483
3pqbVGPPutative oxidoreductase/0.483
3qwbNDPProbable quinone oxidoreductase1.6.5.50.483
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.482
3w5p4OAVitamin D3 receptor/0.482
2cdaNAPGlucose 1-dehydrogenase/0.481
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.481
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.481
4cfaWOPIntegrase/0.481
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.480
1k7fIAVTryptophan synthase alpha chain/0.480
1m9hNAD2,5-diketo-D-gluconic acid reductase A1.1.1.3460.480
2v5aLZLBiotin carboxylase6.3.4.140.480
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.480
2xveFADPutative flavin-containing monooxygenase/0.479
3oetNADErythronate-4-phosphate dehydrogenase/0.479
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.478
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.478
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.478
1r2jFADFkbI/0.477
1zdwFLVPrenyltransferase/0.477
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.477
2watCOAFatty acid synthase subunit alpha2.3.1.860.477
4i6gFADCryptochrome-2/0.477
1y0s331Peroxisome proliferator-activated receptor delta/0.476
4az3S35Lysosomal protective protein3.4.16.50.476
4xldBRLPeroxisome proliferator-activated receptor gamma/0.476
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.475
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.475
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.475
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.475
2ywlFADThioredoxin reductase related protein/0.475
3f63GTXGlutathione transferase GST1-4/0.475
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.475
1bwsNDPGDP-L-fucose synthase/0.474
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.474
3a783EVVitamin D3 receptor/0.474
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.474
3v0m5GWHisto-blood group ABO system transferase/0.474
4fogC2FThymidylate synthase ThyA/0.474
4g67SAHUncharacterized ACR, COG1565 superfamily/0.474
1zg32HIIsoflavone 4'-O-methyltransferase/0.473
2ejvNADL-threonine 3-dehydrogenase/0.473
2vn1FK5Peptidylprolyl isomerase/0.473
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.473
4j7uYTZSepiapterin reductase1.1.1.1530.473
1xp8AGSProtein RecA/0.471
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.471
3af0GDPPantothenate kinase2.7.1.330.471
3k4nFADPyranose 2-oxidase/0.471
3phiNDPShikimate dehydrogenase (NADP(+))/0.471
3vt7VDXVitamin D3 receptor/0.471
3vtdTKDVitamin D3 receptor/0.471
4e2bFMNDehydrogenase/0.471
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.471
1xdpATPPolyphosphate kinase/0.470
3b9oFMNAlkane monoxygenase/0.470
3m31FADEndoplasmic oxidoreductin-11.8.40.470
3vtbTKAVitamin D3 receptor/0.470
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.469
2x7hPFNProstaglandin reductase 310.469
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.469
3imgBZ2Pantothenate synthetase6.3.2.10.469
3q43D66M1 family aminopeptidase3.4.110.469
4psbGA3Cytokinin-specific binding protein/0.469
1fmlRTLRetinol dehydratase/0.468
1qorNDPQuinone oxidoreductase 1/0.468
1qy5NECEndoplasmin/0.468
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.468
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.468
2x7gPVBSRSF protein kinase 22.7.11.10.468
3gwfFADCyclohexanone monooxygenase/0.468
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
3lkhLT6Genome polyprotein2.7.7.480.468
3zhvTDWMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.468
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
1s0zEB1Vitamin D3 receptor/0.467
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.467
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.467
3vf60H6Glucokinase2.7.1.20.467
5p2pDHGPhospholipase A2, major isoenzyme3.1.1.40.467
1dirNADDihydropteridine reductase1.5.1.340.466
1j21ATPArgininosuccinate synthase/0.466
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.466
1oyaFMNNADPH dehydrogenase 11.6.99.10.466
1upw444Oxysterols receptor LXR-beta/0.466
2gvdFKPAdenylate cyclase type 2/0.466
2gvdFKPAdenylate cyclase type 5/0.466
2hasC3OVitamin D3 receptor/0.466
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.466
2r8oT5XTransketolase 1/0.466
2wi72KLHeat shock protein HSP 90-alpha/0.466
3ddw055Glycogen phosphorylase, liver form2.4.1.10.466
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3kp4MIITranscriptional regulator TcaR/0.466
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.466
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.466
4qi7FADCellobiose dehydrogenase/0.466
4z9g1Q5Corticotropin-releasing factor receptor 1/0.466
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.465
1rq1FADEndoplasmic oxidoreductin-11.8.40.465
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.465
2iko7IGRenin3.4.23.150.465
2tpsTPSThiamine-phosphate synthase/0.465
2x9dITCTetracycline repressor protein class D/0.465
3ndjJHZMethyltransferase/0.465
3nr4PYVAbscisic acid receptor PYL2/0.465
3w0gW07Vitamin D3 receptor/0.465
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.465
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.465
4kc1WS1Histo-blood group ABO system transferase/0.465
1zw9H64ATP-dependent molecular chaperone HSP82/0.464
2jb4A14Isopenicillin N synthase1.21.3.10.464
2q8sL92Peroxisome proliferator-activated receptor gamma/0.464
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.464
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.464
3hub469Mitogen-activated protein kinase 14/0.464
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3up3XCAaceDAF-12/0.464
4e2dFMNDehydrogenase/0.464
3sn6P0GBeta-2 adrenergic receptor/0.464
1oycFMNNADPH dehydrogenase 11.6.99.10.463
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.463
2vnhFADNADPH:ferredoxin reductase/0.463
2vqbFADPutative flavin-containing monooxygenase/0.463
3c3xNAPEugenol synthase 11.1.1.3180.463
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3f03FMNPentaerythritol tetranitrate reductase/0.463
3h3qH13Collagen type IV alpha-3-binding protein/0.463
3jynNDPQuinone oxidoreductase/0.463
3tk3CPZCytochrome P450 2B41.14.14.10.463
3v0o4GWHisto-blood group ABO system transferase/0.463
3v2uATPProtein GAL3/0.463
4ipw1G7Mycocyclosin synthase1.14.21.90.463
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.462
1oc1ASVIsopenicillin N synthase1.21.3.10.462
1pw1HELD-alanyl-D-alanine carboxypeptidase3.4.16.40.462
1pz0NAPProtein IolS1.1.10.462
2ejzSAHDiphthine synthase/0.462
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.462
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.462
2xvfFADPutative flavin-containing monooxygenase/0.462
3akn11DFatty acid-binding protein, intestinal/0.462
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.462
3gncQQQGlutaryl-CoA dehydrogenase/0.462
3iaaTYDCalG2/0.462
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3oqkS52Renin3.4.23.150.462
3qlsNDPDihydrofolate reductase1.5.1.30.462
3w0c6DSVitamin D3 receptor/0.462
3w0iO11Vitamin D3 receptor/0.462
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.462
1bwlFMNNADPH dehydrogenase 11.6.99.10.461
1crbRTLRetinol-binding protein 1/0.461
1dr2TAPDihydrofolate reductase1.5.1.30.461
1g6kNADGlucose 1-dehydrogenase1.1.1.470.461
1mczRMNBenzoylformate decarboxylase4.1.1.70.461
1rsgFADPolyamine oxidase FMS1/0.461
1umcTDP2-oxoisovalerate dehydrogenase subunit alpha1.2.4.40.461
1umcTDP2-oxoisovalerate dehydrogenase subunit beta1.2.4.40.461
2gs9SAHUncharacterized protein/0.461
2oyuIMSProstaglandin G/H synthase 11.14.99.10.461
3rbqGLY_ALA_GLY_DAOProtein unc-119 homolog A/0.461
4b4w9L9Bifunctional protein FolD/0.461
4bb3KKAIsopenicillin N synthase1.21.3.10.461
4nh82LCHeat shock protein HSP 90-alpha/0.461
1hb1OCVIsopenicillin N synthase1.21.3.10.460
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.460
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.460
2nr4FMNConserved protein/0.460
2ohvNHLGlutamate racemase/0.460
2pvkP45Casein kinase II subunit alpha2.7.11.10.460
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.460
3b9lAZZSerum albumin/0.460
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
3vdqNAD3-hydroxybutyrate dehydrogenase/0.460
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.460
4fhh0U3Vitamin D3 receptor A/0.460
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
4l1xNAPAldo-keto reductase family 1 member C2/0.460
4v12POGMaoC like domain protein/0.460
4zu44TGWxcM-like protein/0.460
1ddtAPUDiphtheria toxin/0.459
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1fvpFMANon-fluorescent flavoprotein/0.459
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.459
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
2flhZEACytokinin-specific binding protein/0.459
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.459
2pakTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.459
2r8pT6FTransketolase 1/0.459
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3gfbNADL-threonine 3-dehydrogenase/0.459
3pd5TSBThreonine--tRNA ligase6.1.1.30.459
3qe2FADNADPH--cytochrome P450 reductase/0.459
3zhtTD9Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.459
4cigX0PIntegrase/0.459
4df2FMNNADPH dehydrogenase/0.459
4i7fNVEGag-Pol polyprotein2.7.7.490.459
4kc4WS3Histo-blood group ABO system transferase/0.459
4mm729JNa(+):neurotransmitter symporter (Snf family)/0.459
1f4gTP4Thymidylate synthase/0.458
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.458
1ie9VDXVitamin D3 receptor/0.458
1rp4FADEndoplasmic oxidoreductin-11.8.40.458
2fxuBIDActin, alpha skeletal muscle/0.458
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.458
2y6fM9FIsopenicillin N synthase1.21.3.10.458
3af1GDPPantothenate kinase2.7.1.330.458
3atyFMNProstaglandin F2a synthase/0.458
3atzFMNProstaglandin F2a synthase/0.458
3eksCY9Actin-5C/0.458
3h3sH15Collagen type IV alpha-3-binding protein/0.458
3vt8YI3Vitamin D3 receptor/0.458
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.458
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.458
4dlcUMPDeoxyuridine triphosphatase, putative/0.458
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.458
5c1gGDUHisto-blood group ABO system transferase/0.458
1bp6UMPThymidylate synthase/0.457
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.457
1wc4APCAdenylate cyclase/0.457
2cnsACORibosomal-protein-alanine acetyltransferase/0.457
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.457
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.457
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.457
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.457
3d84NDPDihydrofolate reductase1.5.1.30.457
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.457
3ha3SAHHydroxymycolate synthase MmaA42.1.10.457
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3nmpPYVAbscisic acid receptor PYL2/0.457
3q9bB3NAcetylpolyamine amidohydrolase/0.457
3ut5LOCTubulin beta chain/0.457
4mwzSAMPhosphoethanolamine N-methyltransferase, putative/0.457
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.457
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.457
1buxPPSNucleoside diphosphate kinase, cytosolic2.7.4.60.456
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.456
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.456
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.456
2z9dFMNFMN-dependent NADH-azoreductase/0.456
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.456
3kpzZNEVitamin D3 receptor/0.456
3nx2FERFerulic acid decarboxylase/0.456
3p3zP3ZPutative cytochrome P450/0.456
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.456
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.456
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.456
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.456
4g1z0VPVitamin D3 receptor A/0.456
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.456
4k28NADShikimate dehydrogenase family protein/0.456
4qi5FADCellobiose dehydrogenase/0.456
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.456
5fsxADPUncharacterized protein/0.456
1db48INPhospholipase A2, membrane associated/0.455
1e7qNAPGDP-L-fucose synthase/0.455
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1k6tXN1Gag-Pol polyprotein3.4.23.160.455
1o6qR17Squalene--hopene cyclase4.2.1.1290.455
1rzy5ASHistidine triad nucleotide-binding protein 130.455
1u0yPA7Endoplasmin/0.455
1x1aSAMC-20 methyltransferase/0.455
1zeoC01Peroxisome proliferator-activated receptor gamma/0.455
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.455
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.455
3bk2U5PRibonuclease J/0.455
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3ftxRE2Leukotriene A-4 hydrolase3.3.2.60.455
3ieiSAHLeucine carboxyl methyltransferase 12.1.1.2330.455
3p82FMNPentaerythritol tetranitrate reductase/0.455
3up0D7SaceDAF-12/0.455
4a862ANMajor pollen allergen Bet v 1-A/0.455
4at0FADPossible succinate dehydrogenase/0.455
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.455
4oztP1AEcdysone receptor, putative/0.455
4rpjFADUDP-galactopyranose mutase5.4.99.90.455
5emhNAPIridoid synthase1.3.1.990.455
1ay0TPPTransketolase 12.2.1.10.454
1bk0ACVIsopenicillin N synthase1.21.3.10.454
1culFOKAdenylate cyclase type 2/0.454
1culFOKAdenylate cyclase type 5/0.454
1ef92CPMethylmalonyl-CoA decarboxylase4.1.1.410.454
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.454
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.454
1svlADPLarge T antigen3.6.40.454
1ygjRMCPyridoxal kinase2.7.1.350.454
1yw8A75Methionine aminopeptidase 2/0.454
2b3vACODiamine acetyltransferase 1/0.454
2dshSAHDiphthine synthase/0.454
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.454
2iviACWIsopenicillin N synthase1.21.3.10.454
2p33J07Mitogen-activated protein kinase 102.7.11.240.454
2pa7TYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.454
3a1nNADNDP-sugar epimerase/0.454
3gw9VNILanosterol 14-alpha-demethylase/0.454
3gwfNAPCyclohexanone monooxygenase/0.454
3w5rLOAVitamin D3 receptor/0.454
4b8wNAPGDP-L-fucose synthase1.1.1.2710.454
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.454
4dieC5PCytidylate kinase/0.454
4e32DWNMethyltransferase/0.454
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.454
4haiI23Bifunctional epoxide hydrolase 23.1.3.760.454
4jazSTLPeroxisome proliferator-activated receptor gamma/0.454
4kotCE3Uncharacterized protein/0.454
4lsl1YQGag-Pol polyprotein2.7.7.490.454
4q71FADBifunctional protein PutA/0.454
4r81FMNPredicted NADH dehydrogenase/0.454
1h50FMNPentaerythritol tetranitrate reductase/0.453
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.453
1ppjANYCytochrome b/0.453
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.453
1ri1GTGmRNA cap guanine-N7 methyltransferase2.1.1.560.453
1xddAAYIntegrin alpha-L/0.453
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
2gjlFMNNitronate monooxygenase1.13.12.160.453
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
2rtoIMIStreptavidin/0.453
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.453
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.453
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.453
3inrGDUUDP-galactopyranose mutase5.4.99.90.453
3ixp834Ecdysone receptor/0.453
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.453
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.453
3vt3VDXVitamin D3 receptor/0.453
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.453
4a8v2ANMajor pollen allergen Bet v 1-J/0.453
4ambDUDPutative glycosyl transferase/0.453
4emaBRLPeroxisome proliferator-activated receptor gamma/0.453
4kc2WS2Histo-blood group ABO system transferase/0.453
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.453
4qfyDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.453
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.453
4y8wSTRSteroid 21-hydroxylase/0.453
1kquBR4Phospholipase A2, membrane associated/0.452
1kqwRTLCellular retinol-binding protein type II/0.452
1m4dCOAAminoglycoside 2'-N-acetyltransferase2.3.10.452
1p8dCO1Oxysterols receptor LXR-beta/0.452
1trkTPPTransketolase 12.2.1.10.452
1uyePU9Heat shock protein HSP 90-alpha/0.452
1ykdCMPAdenylate cyclase/0.452
2ahrNAPPyrroline-5-carboxylate reductase/0.452
2am22LGUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.452
2hbhXE4Vitamin D3 receptor A/0.452
2j9gANPBiotin carboxylase6.3.4.140.452
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.452
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.452
2uxoTACHTH-type transcriptional regulator TtgR/0.452
2v58LZJBiotin carboxylase6.3.4.140.452
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.452
2zs9ADPPantothenate kinase2.7.1.330.452
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3ha5SFGHydroxymycolate synthase MmaA42.1.10.452
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.452
3orfNADDihydropteridine reductase1.5.1.340.452
3toxNAPPutative oxidoreductase/0.452
3w8eNAD3-hydroxybutyrate dehydrogenase/0.452
4ce9O3NIntegrase/0.452
4dbs0HVAldo-keto reductase family 1 member C3/0.452
4g090VDHistidinol dehydrogenase/0.452
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.452
4mo2FADUDP-galactopyranose mutase/0.452
4mv4ACPBiotin carboxylase6.3.4.140.452
4n3r2GUTankyrase-12.4.2.300.452
4nbiD3YD-tyrosyl-tRNA(Tyr) deacylase/0.452
4xbjIN5Alanine racemase, biosynthetic/0.452
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
5cb3APRO-acetyl-ADP-ribose deacetylase/0.452
5irnADPNucleotide binding oligomerization domain containing 2/0.452
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.451
1f5fDHTSex hormone-binding globulin/0.451
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1uymPU3Heat shock protein HSP 90-beta/0.451
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
2clfF6FTryptophan synthase alpha chain/0.451
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
2gpjFADSiderophore-interacting protein/0.451
2harOCCVitamin D3 receptor/0.451
2hb8MVDVitamin D3 receptor/0.451
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.451
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.451
2w6oOA3Biotin carboxylase6.3.4.140.451
2w71L23Biotin carboxylase6.3.4.140.451
2wdzNADGalactitol dehydrogenase/0.451
3e8r615Disintegrin and metalloproteinase domain-containing protein 173.4.24.860.451
3ivcFG4Pantothenate synthetase6.3.2.10.451
3ln1CELProstaglandin G/H synthase 21.14.99.10.451
3mj4URMUDP-galactopyranose mutase/0.451
3p67FMNPentaerythritol tetranitrate reductase/0.451
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.451
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.451
4b1fKRHGlutamate racemase/0.451
4g2h0VQVitamin D3 receptor A/0.451
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.451
4kovKOVUncharacterized protein/0.451
4l9kEHFSerum albumin/0.451
4ryvZEAProtein LlR18A/0.451
5dg3U21Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase/0.451
5ifiPRXAcetyl-coenzyme A synthetase/0.451
1fxsNAPGDP-L-fucose synthase/0.450
1h51FMNPentaerythritol tetranitrate reductase/0.450
1mp0NADAlcohol dehydrogenase class-31.1.1.10.450
2bl4NADLactaldehyde reductase1.1.1.770.450
2i4qUA4Renin3.4.23.150.450
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.450
2vf0F89Thymidylate synthase/0.450
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.450
2yg6FADPutrescine oxidase/0.450
2ylzFADPhenylacetone monooxygenase1.14.13.920.450
2zynBCDPeriplasmic binding protein/0.450
3gqvNAPEnoyl reductase LovC10.450
3q44D50M1 family aminopeptidase3.4.110.450
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.450
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.450
3vt9YI4Vitamin D3 receptor/0.450
4a83DXCMajor pollen allergen Bet v 1-A/0.450
4azwSAMO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.450
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.450
4bfuZVUPantothenate kinase2.7.1.330.450
4g1y0VOVitamin D3 receptor A/0.450
4g7gVFVLanosterol 14-alpha-demethylase/0.450
4kgmATPUncharacterized protein/0.450
4klaCHDFerrochelatase, mitochondrial4.99.1.10.450
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.450
4l8u9AZSerum albumin/0.450
4xiwAZMCarbonic anhydrase, alpha type/0.450
5dmhADP3-oxo-tetronate kinase/0.450
1fxvPNNPenicillin G acylase3.5.1.110.449
1icpFMN12-oxophytodienoate reductase 11.3.1.420.449
1nhz486Glucocorticoid receptor/0.449
1pkfEPDEpothilone C/D epoxidase1.140.449
1q3aNGHStromelysin-23.4.24.220.449
1qrpHH0Pepsin A-43.4.23.10.449
1wc1TATAdenylate cyclase/0.449
1wuuANPGalactokinase2.7.1.60.449
1ygkRRCPyridoxal kinase2.7.1.350.449
1yhjR6CPyridoxal kinase2.7.1.350.449
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.449
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.449
2qimZEAClass 10 plant pathogenesis-related protein/0.449
2vbdV10Isopenicillin N synthase1.21.3.10.449
2vcmM11Isopenicillin N synthase1.21.3.10.449
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.449
2xweAMFGlucosylceramidase3.2.1.450.449
3dgeADPSensor histidine kinase/0.449
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.449
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
3g5hYTTMycocyclosin synthase1.14.21.90.449
3jziJZLBiotin carboxylase6.3.4.140.449
3n33AESBeta-peptidyl aminopeptidase BapA/0.449
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
3p62FMNPentaerythritol tetranitrate reductase/0.449
3pe2E1BCasein kinase II subunit alpha2.7.11.10.449
3q7fED2Uncharacterized protein/0.449
3qgzADNHistidine triad nucleotide-binding protein 130.449
3tfq07MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
4cdmFO1Deoxyribodipyrimidine photolyase/0.449
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.449
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.449
4kvzSAHPtnL protein/0.449
4phlPILPhosphodiesterase/0.449
4rnuFMNNADPH dehydrogenase 11.6.99.10.449
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.449
5iqiGNPBifunctional AAC/APH2.3.10.449
1fmjRTLRetinol dehydratase/0.448
1m13HYFNuclear receptor subfamily 1 group I member 2/0.448
1txiTX5Vitamin D3 receptor/0.448
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.448
2aviBTNAvidin/0.448
2h55DZ8Heat shock protein HSP 90-alpha/0.448
2j9lATPH(+)/Cl(-) exchange transporter 5/0.448
2r5nTPPTransketolase 1/0.448
2rds1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.448
3egvSAHRibosomal protein L11 methyltransferase2.1.10.448
3ekuCY9Actin-5C/0.448
3gbuATPUncharacterized sugar kinase PH14592.7.10.448
3ibdCPZCytochrome P450 2B61.14.130.448
3iogSDFMetallo-beta-lactamase type 2/0.448
3kkzSAMUncharacterized protein/0.448
3lu8IQXSerum albumin/0.448
3n1s5GPPurine nucleoside phosphoramidase/0.448
3ox4NADAlcohol dehydrogenase 21.1.1.10.448
3pm9FADPutative oxidoreductase/0.448
3rpeFADPutative modulator of drug activity/0.448
3v9y24LPeroxisome proliferator-activated receptor gamma/0.448
3vg9ZMAAdenosine receptor A2a/0.448
3vtcTK3Vitamin D3 receptor/0.448
4a6rTA8Probable aminotransferase/0.448
4a84DXCMajor pollen allergen Bet v 1-A/0.448
4a86H35Major pollen allergen Bet v 1-A/0.448
4ck1OM1Integrase/0.448
4fqsLYAThymidylate synthase ThyA/0.448
4mzuTYDWxcM-like protein/0.448
4pnmNU1Tankyrase-22.4.2.300.448
4r7uUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.448
4yauFADNADPH--cytochrome P450 reductase/0.448
4yvjSFGtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.448
5dbvCOAAldehyde Dehydrogenase/0.448
5hs1VORLanosterol 14-alpha demethylase/0.448
1bpjUMPThymidylate synthase/0.447
1i5cADPChemotaxis protein CheA2.7.13.30.447
1khrCOAStreptogramin A acetyltransferase2.3.10.447
1tl7ONMAdenylate cyclase type 2/0.447
1tl7ONMAdenylate cyclase type 5/0.447
1udaUFGUDP-glucose 4-epimerase5.1.3.20.447
1uydPU8Heat shock protein HSP 90-alpha/0.447
1x1cSAHC-20 methyltransferase/0.447
1xe65FPPlasmepsin-23.4.23.390.447
1y6oMJIPhospholipase A2, major isoenzyme3.1.1.40.447
2du8FADD-amino-acid oxidase1.4.3.30.447
2e20B4PPropionate kinase/0.447
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.447
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.447
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.447
2rlcCHDCholoylglycine hydrolase3.5.1.240.447
2wkmPFYHepatocyte growth factor receptor2.7.10.10.447
2x8hFADThioredoxin glutathione reductase/0.447
3da24MDCarbonic anhydrase 134.2.1.10.447
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
3ielU5PRibonuclease TTHA02523.10.447
3kboNDPGlyoxylate/hydroxypyruvate reductase A/0.447
3kybFADUDP-galactopyranose mutase5.4.99.90.447
3lqfNADGalactitol dehydrogenase/0.447
3p8iFMNPentaerythritol tetranitrate reductase/0.447
3s1dZIRCytokinin dehydrogenase 11.5.99.120.447
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.447
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
3vrtYS2Vitamin D3 receptor/0.447
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.447
4g2i0VQVitamin D3 receptor/0.447
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4nxuADPMitochondrial dynamics protein MID51/0.447
4rvgTYDD-mycarose 3-C-methyltransferase/0.447
4tmcFMNOld yellow enzyme/0.447
5dozNDPJamJ/0.447
5h8tRTLRetinol-binding protein 1/0.447
1bim0QBRenin3.4.23.150.446
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.446
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.446
1gcoNADGlucose 1-dehydrogenase1.1.1.470.446
1h63FMNPentaerythritol tetranitrate reductase/0.446
1j49NADD-lactate dehydrogenase1.1.1.280.446
1nzdUPGDNA beta-glucosyltransferase/0.446
1q23FUAChloramphenicol acetyltransferase2.3.1.280.446
1u1gBBBUridine phosphorylase2.4.2.30.446
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2a4nCOAAac(6')-Ii protein/0.446
2bgjFADNADPH:ferredoxin reductase/0.446
2ctsCOACitrate synthase, mitochondrial2.3.3.10.446
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.446
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.446
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.446
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.446
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.446
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2tctCTCTetracycline repressor protein class D/0.446
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.446
3b70NAPEnoyl reductase LovC10.446
3br3ETHTH-type transcriptional regulator QacR/0.446
3fknFKNMitogen-activated protein kinase 14/0.446
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.446
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.446
3nga3NGCasein kinase II subunit alpha2.7.11.10.446
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.446
3qt62P0Mevalonate diphosphate decarboxylase/0.446
3qwiCUE17beta-hydroxysteroid dehydrogenase/0.446
3rsv3RSBeta-secretase 13.4.23.460.446
3w0hW12Vitamin D3 receptor/0.446
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
4jicFMNGTN Reductase/0.446
4tmbFMNOld yellow enzyme/0.446
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.446
4xo7NAPAldo-keto reductase family 1 member C2/0.446
4yaoFMNNADPH--cytochrome P450 reductase/0.446
6gswGPSGlutathione S-transferase Mu 12.5.1.180.446
1cs4FOKAdenylate cyclase type 2/0.445
1cs4FOKAdenylate cyclase type 5/0.445
1ewyFADFerredoxin--NADP reductase1.18.1.20.445
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.445
1ma0NADAlcohol dehydrogenase class-31.1.1.10.445
1n3rGTPGTP cyclohydrolase 13.5.4.160.445
1nyxDRFPeroxisome proliferator-activated receptor gamma/0.445
1obnASVIsopenicillin N synthase1.21.3.10.445
1pqc444Oxysterols receptor LXR-beta/0.445
1rk3VDXVitamin D3 receptor/0.445
1uxkNADMalate dehydrogenase/0.445
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
1ycfFMNNitric oxide reductase10.445
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.445
2abi1CAMineralocorticoid receptor/0.445
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.445
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.445
2ea2F77Methionine aminopeptidase 2/0.445
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
2givACOHistone acetyltransferase KAT8/0.445
2oazI96Methionine aminopeptidase 2/0.445
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.445
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.445
2vz0D64Pteridine reductase/0.445
2wd9IBPAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.445
2xlsFADPutative flavin-containing monooxygenase/0.445
2xvhFADPutative flavin-containing monooxygenase/0.445
2yj5ATPCopper-transporting ATPase/0.445
3aw9GDUNAD-dependent epimerase/dehydratase/0.445
3bhrTHGThymidylate synthase/0.445
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.445
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3g70A5TRenin3.4.23.150.445
3gkaFMNN-ethylmaleimide reductase/0.445
3gstGPRGlutathione S-transferase Mu 12.5.1.180.445
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3nz4TCAPhenylalanine aminomutase (L-beta-phenylalanine forming)/0.445
3sigAR6Uncharacterized protein/0.445
3stv3HOMethylketone synthase I/0.445
3upr1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.445
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
3w8qAGSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.445
3zraORBProgesterone receptor/0.445
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.445
4du82P0Mevalonate diphosphate decarboxylase/0.445
4g20484Vitamin D3 receptor A/0.445
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4q0kGA3Phytohormone-binding protein/0.445
4rxqDUTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.445
1b87ACOAac(6')-Ii protein/0.444
1cjtFOKAdenylate cyclase type 2/0.444
1cjtFOKAdenylate cyclase type 5/0.444
1eioGCHGastrotropin/0.444
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.444
1lf3EH5Plasmepsin-23.4.23.390.444
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.444
1s3zCOAAminoglycoside N(6')-acetyltransferase type 1/0.444
1w6jR71Lanosterol synthase5.4.99.70.444
1wlvCOAPhenylacetic acid degradation protein PaaI/0.444
1wuaAP8Actin, alpha skeletal muscle/0.444
2abbFMNPentaerythritol tetranitrate reductase/0.444
2dvlFADAcyl-CoA dehydrogenase/0.444
2g5cNADPrephenate dehydrogenase/0.444
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.444
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.444
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.444
2jfz003Glutamate racemase/0.444
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.444
2q59240Peroxisome proliferator-activated receptor gamma/0.444
2qf2GDPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.444
2vprTDCTetracycline repressor protein class H/0.444
2xb5I7TTetracycline repressor protein class D/0.444
2xpwOTCTetracycline repressor protein class D/0.444
2xvq9DSSerum albumin/0.444
2y60M8FIsopenicillin N synthase1.21.3.10.444
2zlcVDXVitamin D3 receptor/0.444
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3f90FMNFlavodoxin/0.444
3fl4FL4Mitogen-activated protein kinase 14/0.444
3g8dADPBiotin carboxylase6.3.4.140.444
3gc8B45Mitogen-activated protein kinase 112.7.11.240.444
3hz5Z64Heat shock protein HSP 90-alpha/0.444
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.444
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3r324CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.444
3tdaPN0Cytochrome P450 2D6/0.444
3tqhNDPQuinone oxidoreductase/0.444
3vrwYS5Vitamin D3 receptor/0.444
3vt5YI2Vitamin D3 receptor/0.444
3zoiM2WIsopenicillin N synthase1.21.3.10.444
4awo99BHeat shock protein HSP 90-alpha/0.444
4b65FADL-ornithine N(5)-monooxygenase/0.444
4c3sNADAldehyde Dehydrogenase/0.444
4ey7E20Acetylcholinesterase3.1.1.70.444
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.444
4g3jVNTLanosterol 14-alpha-demethylase/0.444
4jdcNADProbable pyrroline-5-carboxylate dehydrogenase RocA/0.444
4q0a4OAVitamin D3 receptor A/0.444
4rujVDXVitamin D3 receptor A/0.444
4rupH97Vitamin D3 receptor A/0.444
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.444
4wriOKAOkadaic acid binding protein 2-alpha/0.444
4xmxBESAminopeptidase N3.4.11.20.444
5fm7ADPRuvB-like helicase/0.444
1bp0UMPThymidylate synthase/0.443
1hb3SCVIsopenicillin N synthase1.21.3.10.443
1jnzFADAdenylylsulfate reductase, subunit A (AprA)/0.443
1mmaADPMyosin-2 heavy chain/0.443
1s7lCOAAcetyl transferase/0.443
1swtBTNStreptavidin/0.443
1uamSAHtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.443
1xs7MMIBeta-secretase 13.4.23.460.443
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2fhnBNIAvidin-related protein 4/5/0.443
2fnaADPUncharacterized protein/0.443
2hb7O1CVitamin D3 receptor/0.443
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.443
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.443
2r0pK2CPutative FAD-monooxygenase/0.443
2vbpVB1Isopenicillin N synthase1.21.3.10.443
2vnjFADNADPH:ferredoxin reductase/0.443
2w06FRVCyclin-dependent kinase 22.7.11.220.443
2wo7ASVIsopenicillin N synthase1.21.3.10.443
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.443
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3dr8ACOL-methionine sulfoximine/L-methionine sulfone acetyltransferase/0.443
3ew2BTNHypothetical conserved protein/0.443
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
3gcoVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.443
3i2834NBifunctional epoxide hydrolase 23.3.2.100.443
3mnrSD1Heat shock protein HSP 90-alpha/0.443
3nz2ACOHexapeptide-repeat containing-acetyltransferase/0.443
3pvt3HC1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.443
3q8uADPNucleoside diphosphate kinase/0.443
3qlrNDPDihydrofolate reductase1.5.1.30.443
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.443
3u8hBHPPhospholipase A2, membrane associated/0.443
3vruYS3Vitamin D3 receptor/0.443
3w5tLHPVitamin D3 receptor/0.443
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.443
4ejmNAPPutative zinc-binding dehydrogenase/0.443
4f9mFCMPeroxisome proliferator-activated receptor gamma/0.443
4g48PZBMycocyclosin synthase1.14.21.90.443
4kx6FADFumarate reductase flavoprotein subunit1.3.5.40.443
4ubuCOASteroid 3-ketoacyl-CoA thiolase/0.443
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
5cwa0GAAnthranilate synthase component 14.1.3.270.443
1a80NDP2,5-diketo-D-gluconic acid reductase A1.1.1.3460.442
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1egcCO8Medium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.442
1f4fTP3Thymidylate synthase/0.442
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.442
1nvtNAPShikimate dehydrogenase (NADP(+))/0.442
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.442
1rfuADPPyridoxal kinase2.7.1.350.442
1u1jC2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 12.1.1.140.442
1uyfPU1Heat shock protein HSP 90-alpha/0.442
1ye6NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.442
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.442
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.442
2fxfACODiamine acetyltransferase 1/0.442
2j08IRFDeoxyribodipyrimidine photo-lyase4.1.99.30.442
2lfoGCHFatty acid-binding protein, liver/0.442
2ociTYCValacyclovir hydrolase3.10.442
2tdmUMPThymidylate synthase/0.442
2tplHPPTyrosine phenol-lyase4.1.99.20.442
2xrlDXTTetracycline repressor protein class D/0.442
2xvv9DNSerum albumin/0.442
2ym1FADPhenylacetone monooxygenase1.14.13.920.442
2zbaZBATrichothecene 3-O-acetyltransferase/0.442
2znpK55Peroxisome proliferator-activated receptor delta/0.442
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.442
3i5xANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.442
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3otqMZLBifunctional epoxide hydrolase 23.3.2.100.442
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.442
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.442
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3vt65YIVitamin D3 receptor/0.442
3w5q3KLVitamin D3 receptor/0.442
3zh8C58Protein kinase C iota type2.7.11.130.442
3zsrO3NIntegrase/0.442
4afgQMRAchbp/0.442
4bcsBTNAvidin-related protein 4/5/0.442
4bfvZVVPantothenate kinase2.7.1.330.442
4cezO3NIntegrase/0.442
4e5pNADPhosphonate dehydrogenase1.20.1.10.442
4e9aQAPPeptide deformylase/0.442
4eqgA5AHistidine triad nucleotide-binding protein 130.442
4fv7E94Mitogen-activated protein kinase 12.7.11.240.442
4kxjP34Nucleoprotein/0.442
4lsjLSJGlucocorticoid receptor/0.442
4nmbFADBifunctional protein PutA/0.442
4y7cFADNADPH--cytochrome P450 reductase/0.442
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.442
4k5y1Q5Corticotropin-releasing factor receptor 1/0.442
3pwhZMAAdenosine receptor A2a/0.442
1a8pFADFerredoxin--NADP reductase/0.441
1db1VDXVitamin D3 receptor/0.441
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.441
1frbZSTAldose reductase-related protein 2/0.441
1i9c5ADGlutamate mutase epsilon subunit/0.441
1kiaSAMGlycine N-methyltransferase2.1.1.200.441
1nq7ARLNuclear receptor ROR-beta/0.441
1oi9N20Cyclin-dependent kinase 22.7.11.220.441
1psa0ZLPepsin A3.4.23.10.441
1uy9PU6Heat shock protein HSP 90-alpha/0.441
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.441
2bu9HFVIsopenicillin N synthase1.21.3.10.441
2cekN8TAcetylcholinesterase3.1.1.70.441
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.441
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.441
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.441
2hc4VDXVitamin D3 receptor A/0.441
2jkvNAP6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.441
2rhrEMOPutative ketoacyl reductase1.3.10.441
2rqfJH3Hemolymph juvenile hormone binding protein/0.441
2wzySQXSoluble acetylcholine receptor/0.441
2zl9VDAVitamin D3 receptor/0.441
3cv9VDXVitamin D3 dihydroxylase/0.441
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.441
3d4bDZDNAD-dependent protein deacetylase/0.441
3go4SAHUncharacterized protein/0.441
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.441
3ohh3HHBeta-secretase 13.4.23.460.441
3pm1ETHTH-type transcriptional regulator QacR/0.441
3w8fNAD3-hydroxybutyrate dehydrogenase/0.441
3zsh469Mitogen-activated protein kinase 14/0.441
4b4gKKTGlucose-1-phosphate thymidylyltransferase/0.441
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4cukNAID-lactate dehydrogenase/0.441
4dbzNDPPutative ketoacyl reductase1.3.10.441
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4dvi2IWTankyrase-12.4.2.300.441
4gh5NADShort-chain dehydrogenase/reductase SDR/0.441
4lfiGNPCasein kinase II subunit alpha2.7.11.10.441
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.441
4tuvCPZCytochrome P450 1191.140.441
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.441
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.441
4xnw2IDP2Y purinoceptor 1/0.441
1aj8COACitrate synthase/0.440
1dhiMTXDihydrofolate reductase1.5.1.30.440
1dr3TAPDihydrofolate reductase1.5.1.30.440
1fduNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1hfqMOTDihydrofolate reductase1.5.1.30.440
1j1zATPArgininosuccinate synthase/0.440
1m78NDPDihydrofolate reductase1.5.1.30.440
1ojtFADDihydrolipoyl dehydrogenase/0.440
1s7gNADNAD-dependent protein deacylase 2/0.440
1u4dDBQActivated CDC42 kinase 1/0.440
1yreCOAUncharacterized protein/0.440
2dxdANPNucleoside diphosphate kinase2.7.4.60.440
2hcdBIVVitamin D3 receptor A/0.440
2hk9NAPShikimate dehydrogenase (NADP(+))/0.440
2iyaZIOOleandomycin glycosyltransferase/0.440
2pobGW4Peroxisome proliferator-activated receptor gamma/0.440
2qbuSAHPrecorrin-2 methyltransferase/0.440
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.440
2vn0TDZCytochrome P450 2C8/0.440
2wedPP6Penicillopepsin-13.4.23.200.440
2xlpFADPutative flavin-containing monooxygenase/0.440
2yyyNAPGlyceraldehyde-3-phosphate dehydrogenase1.2.1.590.440
2z3uCRRCytochrome P450/0.440
3adaNADSubunit alpha of sarocosine oxidase/0.440
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.440
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.440
3ns2PYVAbscisic acid receptor PYL2/0.440
3otwCOAPhosphopantetheine adenylyltransferase/0.440
3stw2TDMethylketone synthase I/0.440
4a6cQG9Gag-Pol polyprotein3.4.23.160.440
4a87NARMajor pollen allergen Bet v 1-A/0.440
4b1iA8PPoly(ADP-ribose) glycohydrolase3.2.1.1430.440
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.440
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.440
4fdnFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.440
4fj1GEN17beta-hydroxysteroid dehydrogenase/0.440
4h9tHL4Phosphotriesterase/0.440
4ips1G4Mycocyclosin synthase1.14.21.90.440
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.440
4jxrACOAcetyltransferase/0.440
4u7wNDPMxaA/0.440
4xgxADPFAD:protein FMN transferase/0.440
4yaw2AMNADPH--cytochrome P450 reductase/0.440
5itzLOCTubulin beta-2B chain/0.440