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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3reoEUG(Iso)eugenol O-methyltransferase2.1.1.146

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3reoEUG(Iso)eugenol O-methyltransferase2.1.1.1461.000
3tkyN7I(Iso)eugenol O-methyltransferase2.1.1.1460.553
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.530
2fzjDH3Dihydrofolate reductase1.5.1.30.524
2jizADPATP synthase subunit beta, mitochondrial3.6.3.140.520
1o6qR17Squalene--hopene cyclase4.2.1.1290.519
1y56FMNUncharacterized protein/0.516
1y56FMN382aa long hypothetical sarcosine oxidase/0.516
3acy702Dehydrosqualene synthase/0.512
4iarERM5-hydroxytryptamine receptor 1B/0.512
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.505
3nj0PYVAbscisic acid receptor PYL2/0.502
4ea13RXDehydrosqualene synthase/0.500
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.497
1obnASVIsopenicillin N synthase1.21.3.10.496
1sjwNGVNogalonic acid methyl ester cyclase/0.496
1dr4HBIDihydrofolate reductase1.5.1.30.495
4kak06UDihydrofolate reductase1.5.1.30.495
4pnmNU1Tankyrase-22.4.2.300.495
5jr34MUCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.495
2yk2YJXHeat shock protein HSP 90-alpha/0.494
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.494
2j5sKTAAlr4455 protein/0.493
2xpkZ0MO-GlcNAcase NagJ/0.493
4uohADPNucleoside diphosphate kinase/0.493
3lalKRVGag-Pol polyprotein2.7.7.490.492
4qjcIXEDihydrofolate reductase1.5.1.30.492
5jtbZMAAdenosine receptor A2a/0.492
2fpcSCGStrictosidine synthase4.3.3.20.491
2ipjFFAAldo-keto reductase family 1 member C2/0.491
3h3t16HCollagen type IV alpha-3-binding protein/0.491
2aa71CAMineralocorticoid receptor/0.490
3i587NA2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase/0.490
3k47D09Dihydrofolate reductase1.5.1.30.490
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.490
3tfn2CJDehydrosqualene synthase/0.490
4g95OAGDihydrofolate reductase1.5.1.30.490
4hy6FJ1Heat shock protein HSP 90-alpha/0.490
3biz61EWee1-like protein kinase2.7.10.20.489
3p0gP0GBeta-2 adrenergic receptor/0.489
1kmsLIHDihydrofolate reductase1.5.1.30.488
3wv9FEGHmd co-occurring protein HcgE/0.488
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.488
4uofDATNucleoside diphosphate kinase/0.488
3emlZMAAdenosine receptor A2a/0.488
1blzACVIsopenicillin N synthase1.21.3.10.487
1pd9CO4Dihydrofolate reductase1.5.1.30.487
1tvrTB9Gag-Pol polyprotein2.7.7.490.487
3gg2UGASugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family/0.487
3gieACPSensor histidine kinase DesK2.7.13.30.487
4ea2RWZDehydrosqualene synthase/0.487
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.487
1e2jTHMThymidine kinase/0.486
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.486
5k2bZMAAdenosine receptor A2a/0.486
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.485
3bbfGDPNucleoside diphosphate kinase B2.7.4.60.485
3h18PMSEsterase/lipase/0.485
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.485
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.485
4dsbA8SAbscisic acid receptor PYL3/0.485
4k9yK9YFocal adhesion kinase 12.7.10.20.485
4twnB96Ephrin type-A receptor 32.7.10.10.485
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.484
3zkyWT4Isopenicillin N synthase1.21.3.10.484
4jbtASDCytochrome P450 monooxygenase/0.484
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.483
1uydPU8Heat shock protein HSP 90-alpha/0.483
2j62GSZO-GlcNAcase NagJ/0.483
3h3r14HCollagen type IV alpha-3-binding protein/0.483
3oafOAGDihydrofolate reductase1.5.1.30.483
3vg9ZMAAdenosine receptor A2a/0.483
3wznBTNStreptavidin/0.483
1swtBTNStreptavidin/0.482
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.482
2pl0STITyrosine-protein kinase Lck2.7.10.20.482
1klkPMDDihydrofolate reductase1.5.1.30.481
1w06W05Isopenicillin N synthase1.21.3.10.481
2bjsACVIsopenicillin N synthase1.21.3.10.481
2p1u4TNRetinoic acid receptor RXR-alpha/0.481
3zcnATPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.481
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.480
1yhoTRRDihydrofolate reductase1.5.1.30.480
2hm9TRRDihydrofolate reductase1.5.1.30.480
3nmpPYVAbscisic acid receptor PYL2/0.480
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.480
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.480
4bvbOCZNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.480
4u0k744Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.480
1s3wTQTDihydrofolate reductase1.5.1.30.479
3cseN22Uncharacterized protein/0.479
4iaq2GM5-hydroxytryptamine receptor 1B/0.479
4jlj1NMDeoxycytidine kinase2.7.1.740.479
4m6l21VDihydrofolate reductase1.5.1.30.479
5k2aZMAAdenosine receptor A2a/0.479
1x76697Estrogen receptor beta/0.478
3d73NBBPheromone-binding protein ASP1/0.478
3h4vDVPPteridine reductase 11.5.1.330.478
3lakKR1Gag-Pol polyprotein2.7.7.490.478
5iubCLRAdenosine receptor A2a/0.478
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.477
2ykcYKCHeat shock protein HSP 90-alpha/0.477
3d75NBBPheromone-binding protein ASP1/0.477
3l3rOAGDihydrofolate reductase1.5.1.30.477
4i8vBHFCytochrome P450 1A11.14.14.10.477
4m4821BSodium-dependent dopamine transporter/0.477
4y9lFADAcyl-CoA dehydrogenase family member 11/0.477
5iua6DXAdenosine receptor A2a/0.477
1h35R01Squalene--hopene cyclase4.2.1.1290.476
1kmvLIIDihydrofolate reductase1.5.1.30.476
1m7aMQUDihydrofolate reductase1.5.1.30.476
2iviACWIsopenicillin N synthase1.21.3.10.476
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.476
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.476
3negPYVAbscisic acid receptor PYL1/0.476
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.476
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.476
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.476
1nueGDPNucleoside diphosphate kinase B2.7.4.60.475
2jj1ADPATP synthase subunit alpha, mitochondrial/0.475
2jj1ADPATP synthase subunit beta, mitochondrial3.6.3.140.475
3gi2GHWDihydrofolate reductase1.5.1.30.475
3k4551PDihydrofolate reductase1.5.1.30.475
3kb0A8SAbscisic acid receptor PYL2/0.475
3nxvD2FDihydrofolate reductase1.5.1.30.475
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.475
1ohkCOPDihydrofolate reductase1.5.1.30.474
2jblSMAReaction center protein L chain/0.474
2w8y486Progesterone receptor/0.474
5hs1VORLanosterol 14-alpha demethylase/0.474
1e79ADPATP synthase subunit alpha, mitochondrial/0.473
1e79ADPATP synthase subunit beta, mitochondrial3.6.3.140.473
1hb3SCVIsopenicillin N synthase1.21.3.10.473
1ia1TQ3Dihydrofolate reductase1.5.1.30.473
1m52P17Tyrosine-protein kinase ABL12.7.10.20.473
2bf7HBIPteridine reductase 11.5.1.330.473
2p1v5TNRetinoic acid receptor RXR-alpha/0.473
3g70A5TRenin3.4.23.150.473
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.473
4dm6TTBRetinoic acid receptor beta/0.473
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.473
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.473
1bmfADPATP synthase subunit alpha, mitochondrial/0.472
1bmfADPATP synthase subunit beta, mitochondrial3.6.3.140.472
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.472
1oc1ASVIsopenicillin N synthase1.21.3.10.472
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.472
2io6330Wee1-like protein kinase2.7.10.20.472
1dajMOTDihydrofolate reductase1.5.1.30.471
1dghNDPCatalase1.11.1.60.471
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.471
1v7aFRCAdenosine deaminase3.5.4.40.471
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.471
2in6839Wee1-like protein kinase2.7.10.20.471
2z7gEH9Adenosine deaminase3.5.4.40.471
3rg9WRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.471
3ry2BTNStreptavidin/0.471
4apuOR8Progesterone receptor/0.471
4c2wANPAurora kinase B-A2.7.11.10.471
5k2cZMAAdenosine receptor A2a/0.471
1u3s797Estrogen receptor beta/0.470
1uzwCDHIsopenicillin N synthase1.21.3.10.470
1zdwFLVPrenyltransferase/0.470
2cl5BIECatechol O-methyltransferase2.1.1.60.470
2i9kSAHModification methylase HhaI2.1.1.370.470
2jb4A14Isopenicillin N synthase1.21.3.10.470
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.470
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.470
3v2yML5Sphingosine 1-phosphate receptor 1/0.470
1fkoEFZGag-Pol polyprotein2.7.7.490.469
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.469
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
3dokGWJPol protein/0.469
3h3sH15Collagen type IV alpha-3-binding protein/0.469
3nxoD2BDihydrofolate reductase1.5.1.30.469
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.469
4dneDTBStreptavidin/0.469
4h9753SDihydrofolate reductase1.5.1.30.469
4ivy1GTEstrogen receptor/0.469
4p68MTXDihydrofolate reductase/0.469
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.469
1bq1CB3Thymidylate synthase/0.468
1hfrMOTDihydrofolate reductase1.5.1.30.468
1m79MQ1Dihydrofolate reductase1.5.1.30.468
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.468
3d80Q22Dihydrofolate reductase1.5.1.30.468
3eppSFGmRNA cap guanine-N7 methyltransferase2.1.1.560.468
3q95ESLEstrogen receptor/0.468
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.468
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.468
5iu86DZAdenosine receptor A2a/0.468
5uviZMAAdenosine receptor A2a/0.468
1exa394Retinoic acid receptor gamma/0.467
1hb1OCVIsopenicillin N synthase1.21.3.10.467
1jtqLY3Thymidylate synthase/0.467
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.467
1s3uTQDDihydrofolate reductase1.5.1.30.467
1t76DHTAndrogen receptor/0.467
2izgBTNStreptavidin/0.467
2pitDHTAndrogen receptor/0.467
2ydvNECAdenosine receptor A2a/0.467
3cd2MTXDihydrofolate reductase1.5.1.30.467
3d2dRENReticuline oxidase1.21.3.30.467
3d74NBBPheromone-binding protein ASP1/0.467
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.467
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
3qly55VUncharacterized protein/0.467
3sai9DRDihydrofolate reductase/0.467
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.467
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.467
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.467
5iu4ZMAAdenosine receptor A2a/0.467
7dfrFOLDihydrofolate reductase1.5.1.30.467
1lrhNLAAuxin-binding protein 1/0.466
1pq6965Oxysterols receptor LXR-beta/0.466
2bbqPFGThymidylate synthase/0.466
2igxA1TPlasmepsin 2/0.466
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.466
2pioDHTAndrogen receptor/0.466
2rtnIMIStreptavidin/0.466
2z3uCRRCytochrome P450/0.466
3nxtD2EDihydrofolate reductase1.5.1.30.466
3ukrCKHActin-related protein 3/0.466
3ukrCKHActin-related protein 2/0.466
3vi5M4MHematopoietic prostaglandin D synthase/0.466
4ddrMMVDihydrofolate reductase1.5.1.30.466
4j6cSTRCytochrome P450 monooxygenase/0.466
4z28BTNHoefavidin/0.466
5k2dZMAAdenosine receptor A2a/0.466
1fcy564Retinoic acid receptor gamma/0.465
1kziTHGThymidylate synthase/0.465
1t7tDHTAndrogen receptor/0.465
1u9e397Estrogen receptor beta/0.465
2rtdBTNStreptavidin/0.465
3bqdDAYGlucocorticoid receptor/0.465
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.465
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.465
3jzfJZKBiotin carboxylase6.3.4.140.465
4bchT7ZCyclin-dependent kinase 92.7.11.220.465
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.465
1diuBDMDihydrofolate reductase1.5.1.30.464
1gs4ZK5Androgen receptor/0.464
1rdtL79Retinoic acid receptor RXR-alpha/0.464
1rh3MTXDihydrofolate reductase1.5.1.30.464
1s36CEIObelin/0.464
2bu9HFVIsopenicillin N synthase1.21.3.10.464
3cqeP91Wee1-like protein kinase2.7.10.20.464
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.464
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.464
4edfUPGUDP-glucose 6-dehydrogenase1.1.1.220.464
4g8cC6LAlpha/beta hydrolase fold protein/0.464
4j6dTESCytochrome P450 monooxygenase/0.464
4n1fCZHObelin/0.464
5epvACPBlue-light-activated histidine kinase2.7.13.30.464
4phu2YBFree fatty acid receptor 1/0.464
1bk0ACVIsopenicillin N synthase1.21.3.10.463
1cd2FOLDihydrofolate reductase1.5.1.30.463
1dgbNDPCatalase1.11.1.60.463
1lcoPPYCytochrome b2, mitochondrial1.1.2.30.463
1mvtDTMDihydrofolate reductase1.5.1.30.463
1nceCB3Thymidylate synthase/0.463
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.463
1s9qOHTEstrogen-related receptor gamma/0.463
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.463
1sreHABStreptavidin/0.463
1x7rGENEstrogen receptor/0.463
1xdkREARetinoic acid receptor beta/0.463
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
2piuDHTAndrogen receptor/0.463
2rtfBTNStreptavidin/0.463
2rtoIMIStreptavidin/0.463
2tohHBITyrosine 3-monooxygenase1.14.16.20.463
2w5bAGSSerine/threonine-protein kinase Nek22.7.11.10.463
3bgiSAHThiopurine S-methyltransferase2.1.1.670.463
3datMTXDihydrofolate reductase/0.463
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
4bwaN0BPyrrolysine--tRNA ligase/0.463
4h9506UDihydrofolate reductase1.5.1.30.463
4iw61GUEstrogen receptor/0.463
4qa0SHHHistone deacetylase 83.5.1.980.463
1e7aPFLSerum albumin/0.462
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.462
1yy44NAEstrogen receptor beta/0.462
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.462
2q7kTESAndrogen receptor/0.462
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.462
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3hv3R49Mitogen-activated protein kinase 14/0.462
3n0yAPCAdenylate cyclase 2/0.462
3njoPYVAbscisic acid receptor PYR1/0.462
3oapREARetinoic acid receptor RXR-alpha/0.462
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.462
4uogYYYNucleoside diphosphate kinase/0.462
1e92HBIPteridine reductase 11.5.1.330.461
1qiqACCIsopenicillin N synthase1.21.3.10.461
2bakAQZMitogen-activated protein kinase 14/0.461
2ewaSB2Mitogen-activated protein kinase 14/0.461
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.461
2piwDHTAndrogen receptor/0.461
2rabNADGlutathione amide reductase/0.461
2ykbYKBHeat shock protein HSP 90-alpha/0.461
3a7dFBNCatechol O-methyltransferase2.1.1.60.461
3mhtSAHModification methylase HhaI2.1.1.370.461
3qclNXVReceptor-type tyrosine-protein phosphatase gamma3.1.3.480.461
3qfcFADNADPH--cytochrome P450 reductase/0.461
4a9yAQZMitogen-activated protein kinase 14/0.461
4hqvQEIQueuine tRNA-ribosyltransferase2.4.2.290.461
4kbn25UDihydrofolate reductase1.5.1.30.461
4mr61K0Bromodomain-containing protein 2/0.461
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.461
1crbRTLRetinol-binding protein 1/0.460
1dubCAAEnoyl-CoA hydratase, mitochondrial4.2.1.170.460
1lcwSHMStreptavidin/0.460
1mk5BTNStreptavidin/0.460
1mvsDTMDihydrofolate reductase1.5.1.30.460
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
1qjfACSIsopenicillin N synthase1.21.3.10.460
1sqqOSTCytochrome b/0.460
1vruAAPGag-Pol polyprotein2.7.7.490.460
1w7kADPDihydrofolate synthase/folylpolyglutamate synthase6.3.2.120.460
2bktRPFRenin3.4.23.150.460
2kceD16Thymidylate synthase/0.460
2ydoADNAdenosine receptor A2a/0.460
3b9lAZZSerum albumin/0.460
3f3y4OABile salt sulfotransferase2.8.2.140.460
3jw5TOPDihydrofolate reductase/0.460
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
3up3XCAaceDAF-12/0.460
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
3zs5SB2Mitogen-activated protein kinase 14/0.460
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.460
4i9i1DYTankyrase-12.4.2.300.460
4kfj1R0Dihydrofolate reductase1.5.1.30.460
4mk928RGenome polyprotein2.7.7.480.460
4oeaDHTAndrogen receptor/0.460
4ofuDHTAndrogen receptor/0.460
4rbs0RVMetallo-beta-lactamase type 2/0.460
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.460
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.459
1kkq471Peroxisome proliferator-activated receptor alpha/0.459
1ly4COQDihydrofolate reductase1.5.1.30.459
2b5j3ACGag-Pol polyprotein2.7.7.490.459
2bfpH4BPteridine reductase 11.5.1.330.459
2rtpIMIStreptavidin/0.459
2tscCB3Thymidylate synthase/0.459
2uxhQUEHTH-type transcriptional regulator TtgR/0.459
2uz2BTNAvd protein/0.459
2vbpVB1Isopenicillin N synthase1.21.3.10.459
2w3aTOPDihydrofolate reductase1.5.1.30.459
2ylqTESAndrogen receptor/0.459
2z2w770Wee1-like protein kinase2.7.10.20.459
3ghvGHCDihydrofolate reductase1.5.1.30.459
3k1wBFXRenin3.4.23.150.459
3kdiA8SAbscisic acid receptor PYL2/0.459
3ntz3TZDihydrofolate reductase1.5.1.30.459
3zraORBProgesterone receptor/0.459
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4equG6ISerine/threonine-protein kinase 102.7.11.10.459
4g2i0VQVitamin D3 receptor/0.459
4h4m494Gag-Pol polyprotein2.7.7.490.459
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.459
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.458
1jtuLYBThymidylate synthase/0.458
1ludTRRDihydrofolate reductase1.5.1.30.458
1m78CLZDihydrofolate reductase1.5.1.30.458
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.458
1s19MC9Vitamin D3 receptor/0.458
2fyuFDNCytochrome b/0.458
2j9lATPH(+)/Cl(-) exchange transporter 5/0.458
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.458
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2rteBTNStreptavidin/0.458
2y30SM8Putative repressor SimReg2/0.458
2z1wBDIQueuine tRNA-ribosyltransferase2.4.2.290.458
3aklADPSerine/threonine-protein kinase CtkA2.7.11.10.458
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.458
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.458
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.458
3t0kDCQSulfide-quinone reductase/0.458
3t2wBTNAvidin/streptavidin/0.458
3v94WYQPhosphodiesterase/0.458
4at2ASDPossible succinate dehydrogenase/0.458
4bvhOCZNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.458
4iyg1HUStrictosidine synthase4.3.3.20.458
1coyANDCholesterol oxidase1.1.3.60.457
1e3kR18Progesterone receptor/0.457
1ly3COGDihydrofolate reductase1.5.1.30.457
1mj3HXCEnoyl-CoA hydratase, mitochondrial4.2.1.170.457
1n5qTNCActVA 6 protein/0.457
1rx6DDFDihydrofolate reductase1.5.1.30.457
1t74DHTAndrogen receptor/0.457
1z6tADPApoptotic protease-activating factor 1/0.457
2aazCB3Thymidylate synthase2.1.1.450.457
2bxqIMNSerum albumin/0.457
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.457
2xlrFADPutative flavin-containing monooxygenase/0.457
2ylpTESAndrogen receptor/0.457
2zozETTranscriptional regulator/0.457
3ewrAPRReplicase polyprotein 1a3.4.220.457
3pdtADPMyosin heavy chain kinase A2.7.11.70.457
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.457
3q2mCKISpectinomycin phosphotransferase/0.457
4dscA8SAbscisic acid receptor PYL3/0.457
4gg70J8Hepatocyte growth factor receptor2.7.10.10.457
9mhtSAHModification methylase HhaI2.1.1.370.457
5g53NECAdenosine receptor A2a/0.457
1rkhVD2Vitamin D3 receptor/0.456
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.456
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
2bfmTOPPteridine reductase 11.5.1.330.456
2fs4PZ1Renin3.4.23.150.456
2pulACPMethylthioribose kinase2.7.1.1000.456
2vcmM11Isopenicillin N synthase1.21.3.10.456
2vi5Y196,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
2wqoVGKSerine/threonine-protein kinase Nek22.7.11.10.456
2xvw9NRSerum albumin/0.456
2ynhEURGag-Pol polyprotein2.7.7.490.456
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.456
3arvSAUChitinase A/0.456
3iptEQUSteroid Delta-isomerase5.3.3.10.456
3nmvPYVAbscisic acid receptor PYL2/0.456
3pqbVGPPutative oxidoreductase/0.456
3tq8TOPDihydrofolate reductase/0.456
3wixLC3Induced myeloid leukemia cell differentiation protein Mcl-1/0.456
4bkjSTIEpithelial discoidin domain-containing receptor 12.7.10.10.456
4eiyZMAAdenosine receptor A2a/0.456
4el9AFERibosomal protein S6 kinase alpha-32.7.11.10.456
4hmbPZZPhospholipase A2 VRV-PL-VIIIa/0.456
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.456
1aoeGW3Dihydrofolate reductase1.5.1.30.455
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1jujLYAThymidylate synthase2.1.1.450.455
1kceCB3Thymidylate synthase/0.455
1q3hANPCystic fibrosis transmembrane conductance regulator/0.455
1q6nP90Tyrosine-protein phosphatase non-receptor type 13.1.3.480.455
1s3yTQTDihydrofolate reductase1.5.1.30.455
2ban357Gag-Pol polyprotein2.7.7.490.455
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.455
2izjBTNStreptavidin/0.455
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.455
2opqHBQGag-Pol polyprotein2.7.7.490.455
2pupADPMethylthioribose kinase2.7.1.1000.455
2xtbKRMAdenosine kinase, putative/0.455
2yloTESAndrogen receptor/0.455
3hz137DHeat shock protein HSP 90-alpha/0.455
3mb601ICasein kinase II subunit alpha2.7.11.10.455
3nr4PYVAbscisic acid receptor PYL2/0.455
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.455
3pd3A3TThreonine--tRNA ligase6.1.1.30.455
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.455
3qlwN22Dihydrofolate reductase1.5.1.30.455
3vt3VDXVitamin D3 receptor/0.455
4jlm1NNDeoxycytidine kinase2.7.1.740.455
4nbjD3YD-tyrosyl-tRNA(Tyr) deacylase/0.455
4qjqOTRLactoperoxidase/0.455
5h8tRTLRetinol-binding protein 1/0.455
5iqbGNPBifunctional AAC/APH2.3.10.455
1avdBTNAvidin/0.454
1efzPRFQueuine tRNA-ribosyltransferase2.4.2.290.454
1jomFFODihydrofolate reductase1.5.1.30.454
1kdmDHTSex hormone-binding globulin/0.454
1rd4L08Integrin alpha-L/0.454
1s3vTQDDihydrofolate reductase1.5.1.30.454
1t7fDHTAndrogen receptor/0.454
1upw444Oxysterols receptor LXR-beta/0.454
2aaxPDNMineralocorticoid receptor/0.454
2gj3FADNitrogen fixation regulatory protein2.7.13.30.454
2pixDHTAndrogen receptor/0.454
2yayDUPDUTPase/0.454
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.454
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.454
3l8sBFFMitogen-activated protein kinase 14/0.454
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
3w0aDS5Vitamin D3 receptor/0.454
4deg0JJHepatocyte growth factor receptor2.7.10.10.454
4ej1FOLDihydrofolate reductase1.5.1.30.454
4gevCB3Thymidylate synthase/0.454
4h4o506Gag-Pol polyprotein2.7.7.490.454
4l8u9AZSerum albumin/0.454
4lgaA2OAbscisic acid receptor PYL2/0.454
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.453
1p8dCO1Oxysterols receptor LXR-beta/0.453
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
1wklATPNucleoside diphosphate kinase/0.453
1xj7DHTAndrogen receptor/0.453
2a9z26AAdenosine kinase2.7.1.200.453
2h94FADLysine-specific histone demethylase 1A10.453
2lbdREARetinoic acid receptor gamma/0.453
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.453
2oscMUHAngiopoietin-1 receptor2.7.10.10.453
2qk8MTXDihydrofolate reductase/0.453
2xvv9DNSerum albumin/0.453
2y60M8FIsopenicillin N synthase1.21.3.10.453
3bfa9ODOdorant binding protein ASP1/0.453
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.453
3ielU5PRibonuclease TTHA02523.10.453
3is9AC7Gag-Pol polyprotein2.7.7.490.453
3ndvAICBeta-peptidyl aminopeptidase BapA/0.453
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.453
4ap1NAPSteroid monooxygenase/0.453
4dymIYZActivin receptor type-12.7.11.300.453
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.453
4h380YXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.453
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4hyf1AKTankyrase-22.4.2.300.453
4kf1HT5Aryldialkylphosphatase3.1.8.10.453
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.453
4li61XOTankyrase-12.4.2.300.453
4o71CPBBromodomain-containing protein 4/0.453
4ldeP0GBeta-2 adrenergic receptor/0.453
1hniAAAGag-Pol polyprotein2.7.7.490.452
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.452
2aa6STRMineralocorticoid receptor/0.452
2aclL05Oxysterols receptor LXR-alpha/0.452
2bj4OHTEstrogen receptor/0.452
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.452
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.452
2jkcFADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.452
2wonZZEGag-Pol polyprotein2.7.7.490.452
2yjxYJXHeat shock protein HSP 90-alpha/0.452
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.452
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.452
3dkoIHZEphrin type-A receptor 72.7.10.10.452
3frfXCFDihydrofolate reductase1.5.1.30.452
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
3lfcZ86Mitogen-activated protein kinase 14/0.452
3lfeZ84Mitogen-activated protein kinase 14/0.452
3p8iFMNPentaerythritol tetranitrate reductase/0.452
3rimTPPTransketolase2.2.1.10.452
3seqNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.452
4hni16WCasein kinase I isoform epsilon2.7.11.10.452
4ixeIXEDihydrofolate reductase1.5.1.30.452
4nbb9CATerminal oxygenase component of carbazole/0.452
4othDRNSerine/threonine-protein kinase N1/0.452
1ep4S11Gag-Pol polyprotein2.7.7.490.451
1hk5T44Serum albumin/0.451
1mczRMNBenzoylformate decarboxylase4.1.1.70.451
1z4iUMP5'(3')-deoxyribonucleotidase, mitochondrial3.1.30.451
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2fzhDH1Dihydrofolate reductase1.5.1.30.451
2izfBTNStreptavidin/0.451
2jn3JN3Fatty acid-binding protein, liver/0.451
2oazI96Methionine aminopeptidase 2/0.451
2ofv242Tyrosine-protein kinase Lck2.7.10.20.451
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
2vq3NAPMetalloreductase STEAP3/0.451
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.451
2zbaZBATrichothecene 3-O-acetyltransferase/0.451
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.451
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3wthIM4Acetylcholine-binding protein/0.451
4aosNAPSteroid monooxygenase/0.451
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.451
4mrxCZHObelin/0.451
5f2kSAHUncharacterized protein/0.451
1c1bGCAGag-Pol polyprotein2.7.7.490.450
1disBDMDihydrofolate reductase1.5.1.30.450
1e3gR18Androgen receptor/0.450
1fbyREARetinoic acid receptor RXR-alpha/0.450
1ie8KH1Vitamin D3 receptor/0.450
1lhuESTSex hormone-binding globulin/0.450
1mrqSTRAldo-keto reductase family 1 member C1/0.450
1nq24HYThyroid hormone receptor beta/0.450
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
1srhMOBStreptavidin/0.450
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.450
1zg32HIIsoflavone 4'-O-methyltransferase/0.450
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.450
2bfaCB3Pteridine reductase 11.5.1.330.450
2fmn4HF5,10-methylenetetrahydrofolate reductase1.5.1.200.450
2hamC33Vitamin D3 receptor/0.450
2izlIMIStreptavidin/0.450
2rtkGLLStreptavidin/0.450
2v59LZKBiotin carboxylase6.3.4.140.450
2vmyFFOSerine hydroxymethyltransferase/0.450
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
3dd125DGlycogen phosphorylase, liver form2.4.1.10.450
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
3t195MAGag-Pol polyprotein2.7.7.490.450
3w78CBDFMN-dependent NADH-azoreductase/0.450
4bmpFMNProtein NrdI/0.450
4fkxCDPNucleoside diphosphate kinase/0.450
4ia1BIVVitamin D3 receptor A/0.450
4m8hR4MRetinoic acid receptor RXR-alpha/0.450
4nh92LCEndoplasmin/0.450
4q15HFGProline--tRNA ligase6.1.1.150.450
3pwhZMAAdenosine receptor A2a/0.450
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
1kt5RTLRetinol-binding protein 4/0.449
1tvcFDAMethane monooxygenase component C1.14.13.250.449
2c9dPHR6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
2izhBTNStreptavidin/0.449
2izkGLLStreptavidin/0.449
2l98STLTroponin C, slow skeletal and cardiac muscles/0.449
2qgtEEDEstrogen receptor/0.449
2wo7ASVIsopenicillin N synthase1.21.3.10.449
2xveFADPutative flavin-containing monooxygenase/0.449
2zcePYLPyrrolysine--tRNA ligase/0.449
3a8iC2FAminomethyltransferase2.1.2.100.449
3e01PZ2Gag-Pol polyprotein2.7.7.490.449
3gb4D3MDdmC/0.449
3ix4TX1Transcriptional activator protein LasR/0.449
3qm4PN0Cytochrome P450 2D6/0.449
3tq9MTXDihydrofolate reductase/0.449
3zloX8UBcl-2-like protein 1/0.449
3zze6XPHepatocyte growth factor receptor2.7.10.10.449
4b6l9ZPSerine/threonine-protein kinase PLK32.7.11.210.449
4b8mVX6Aurora kinase B-A2.7.11.10.449
4gdaBTNStreptavidin/0.449
4lsjLSJGlucocorticoid receptor/0.449
5c80URIUridine phosphorylase/0.449
1aiqCB3Thymidylate synthase/0.448
1cqp803Integrin alpha-L/0.448
1dlrMXADihydrofolate reductase1.5.1.30.448
1dreMTXDihydrofolate reductase1.5.1.30.448
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.448
1ne4RP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.448
1nenDNTSuccinate dehydrogenase iron-sulfur subunit1.3.5.10.448
1nenDNTSuccinate dehydrogenase cytochrome b556 subunit/0.448
1s0zEB1Vitamin D3 receptor/0.448
1trgCB3Thymidylate synthase/0.448
1wsvTHHAminomethyltransferase, mitochondrial/0.448
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
1y6bAAXVascular endothelial growth factor receptor 22.7.10.10.448
2aclREARetinoic acid receptor RXR-alpha/0.448
2bn4FADNADPH--cytochrome P450 reductase/0.448
2fziDH3Dihydrofolate reductase1.5.1.30.448
2g263LGRenin3.4.23.150.448
2gzl2AA2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.448
2hb8MVDVitamin D3 receptor/0.448
2oalFADFlavin-dependent tryptophan halogenase RebH1.14.19.90.448
3d76NBBPheromone-binding protein ASP1/0.448
3ew2BTNHypothetical conserved protein/0.448
3fy8XCFDihydrofolate reductase1.5.1.30.448
3gkjHC3Niemann-Pick C1 protein/0.448
3i8aN22Dihydrofolate reductase1.5.1.30.448
3pd2A3SThreonine--tRNA ligase6.1.1.30.448
3u8dU8DPhospholipase A2, membrane associated/0.448
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
3vhuSNLMineralocorticoid receptor/0.448
3vi7CBDHematopoietic prostaglandin D synthase/0.448
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.448
3zoiM2WIsopenicillin N synthase1.21.3.10.448
3zr7OR8Progesterone receptor/0.448
4at5MUJBDNF/NT-3 growth factors receptor2.7.10.10.448
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.448
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.448
4e6a0O9Mitogen-activated protein kinase 14/0.448
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4kfbT27Gag-Pol polyprotein2.7.7.490.448
4u95MIYMultidrug efflux pump subunit AcrB/0.448
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.448
5bn4ANPV-type ATP synthase alpha chain/0.448
3qakUKAAdenosine receptor A2a/0.448
1df8BTNStreptavidin/0.447
1hlk113Metallo-beta-lactamase type 2/0.447
1kyzFERCaffeic acid 3-O-methyltransferase2.1.1.680.447
1nbhSAMGlycine N-methyltransferase2.1.1.200.447
1skmSAHModification methylase HhaI2.1.1.370.447
1t7rDHTAndrogen receptor/0.447
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.447
1vj3TABDihydrofolate reductase1.5.1.30.447
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
2qw8NAPEugenol synthase 11.1.1.3180.447
2vt4P32Beta-1 adrenergic receptor/0.447
2w3mFOLDihydrofolate reductase1.5.1.30.447
2y53NAP3,4-dehydroadipyl-CoA semialdehyde dehydrogenase/0.447
3fgoACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.447
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3of3DIHPurine nucleoside phosphorylase DeoD-type 1/0.447
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
3tp0FO5HTH-type transcriptional regulator EthR/0.447
3wiyLC6Induced myeloid leukemia cell differentiation protein Mcl-1/0.447
4bx7B4FStreptavidin/0.447
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4hdrDMDNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase/0.447
4hdrDMDArsB/0.447
4jv41ORcAMP-dependent protein kinase type I-alpha regulatory subunit/0.447
4k4j1O8Retinoic acid receptor RXR-alpha/0.447
4l1xSTRAldo-keto reductase family 1 member C2/0.447
4mmd29ENa(+):neurotransmitter symporter (Snf family)/0.447
4mmf29QNa(+):neurotransmitter symporter (Snf family)/0.447
4pkl1GHUncharacterized protein/0.447
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.447
4zs2FLUAlpha-ketoglutarate-dependent dioxygenase FTO/0.447
5eq1BEAPeregrin/0.447
7mhtSAHModification methylase HhaI2.1.1.370.447
1bucFADAcyl-CoA dehydrogenase, short-chain specific1.3.8.10.446
1krv147Galactoside O-acetyltransferase2.3.1.180.446
1mvcBM6Retinoic acid receptor RXR-alpha/0.446
1uy6PU3Heat shock protein HSP 90-alpha/0.446
1x8b824Wee1-like protein kinase2.7.10.20.446
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.446
2fhnBNIAvidin-related protein 4/5/0.446
2hc4VDXVitamin D3 receptor A/0.446
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
2ociTYCValacyclovir hydrolase3.10.446
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.446
2wdqCBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.446
2wdqCBESuccinate dehydrogenase cytochrome b556 subunit/0.446
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
2zb1GK4Mitogen-activated protein kinase 14/0.446
2zi53L1Deoxycytidine kinase2.7.1.740.446
3akkADPSerine/threonine-protein kinase CtkA2.7.11.10.446
3ctj320Hepatocyte growth factor receptor2.7.10.10.446
3d77NBBPheromone-binding protein ASP1/0.446
3fznD7KBenzoylformate decarboxylase4.1.1.70.446
3hy4N5G5-formyltetrahydrofolate cyclo-ligase6.3.3.20.446
3jq7DX2Pteridine reductase, putative/0.446
3sh25DRDihydrofolate reductase1.5.1.30.446
3w5q3KLVitamin D3 receptor/0.446
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.446
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.446
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.446
4hshQEIQueuine tRNA-ribosyltransferase2.4.2.290.446
4hwkSFYSepiapterin reductase1.1.1.1530.446
4j6bPLOCytochrome P450 monooxygenase/0.446
4kd79DRDihydrofolate reductase1.5.1.30.446
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.446
4x24TDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.446
4ldlXQCBeta-2 adrenergic receptor/0.446
3rfmCFFAdenosine receptor A2a/0.446
1dlsMTXDihydrofolate reductase1.5.1.30.445
1gwqZTWEstrogen receptor/0.445
1olmVTQSEC14-like protein 2/0.445
1revTB9Gag-Pol polyprotein2.7.7.490.445
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
1rszDIHPurine nucleoside phosphorylase2.4.2.10.445
1sriDMBStreptavidin/0.445
1u3gTHF5-formyltetrahydrofolate cyclo-ligase6.3.3.20.445
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.445
2a3iC0RMineralocorticoid receptor/0.445
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.445
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2pipDHTAndrogen receptor/0.445
2rtgBTNStreptavidin/0.445
2wd8VGFPteridine reductase/0.445
2yatEEUEstrogen receptor/0.445
3bi6396Wee1-like protein kinase2.7.10.20.445
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.445
3c3dFO12-phospho-L-lactate transferase/0.445
3fu83DMLaccase-11.10.3.20.445
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.445
3h0a9RARetinoic acid receptor RXR-alpha/0.445
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.445
3kpzZNEVitamin D3 receptor/0.445
3mneDEXGlucocorticoid receptor/0.445
3nhuM42Ribosyldihydronicotinamide dehydrogenase [quinone]/0.445
3nxrD2DDihydrofolate reductase1.5.1.30.445
3o9lLPNRenin3.4.23.150.445
3q0vLL4HTH-type transcriptional regulator EthR/0.445
3r6pA8SAbscisic acid receptor PYL10/0.445
4a86H35Major pollen allergen Bet v 1-A/0.445
4bjcRPBTankyrase-22.4.2.300.445
4e37NDPCatalase1.11.1.60.445
4eilCB3Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
4f7l0SOCyclin-dependent kinase 82.7.11.220.445
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4g1nNZTPyruvate kinase PKM2.7.1.400.445
4iw8KN3Estrogen receptor/0.445
4m6kFOLDihydrofolate reductase1.5.1.30.445
4mhtSAHModification methylase HhaI2.1.1.370.445
5cp4CAMCamphor 5-monooxygenase1.14.15.10.445
1gt5BZQOdorant-binding protein/0.444
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.444
1kqwRTLCellular retinol-binding protein type II/0.444
1kzjCB3Thymidylate synthase/0.444
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.444
1odnAPVIsopenicillin N synthase1.21.3.10.444
1pqc444Oxysterols receptor LXR-beta/0.444
1qxlFR8Adenosine deaminase3.5.4.40.444
1srfMTBStreptavidin/0.444
1uykPUXHeat shock protein HSP 90-alpha/0.444
1w2cANPInositol-trisphosphate 3-kinase A2.7.1.1270.444
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2b1z17MEstrogen receptor/0.444
2gpvOHTEstrogen-related receptor gamma/0.444
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.444
2j7cIDEBeta-glucosidase A3.2.1.210.444
2oaxSNLMineralocorticoid receptor/0.444
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.444
2pklDHTAndrogen receptor/0.444
2q7gCCLPyrrolysine--tRNA ligase/0.444
2v5aLZLBiotin carboxylase6.3.4.140.444
2vbdV10Isopenicillin N synthase1.21.3.10.444
3ebiBEYM1 family aminopeptidase3.4.110.444
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.444
3fowIMHPurine nucleoside phosphorylase/0.444
3lamKRPGag-Pol polyprotein2.7.7.490.444
3n10CMPAdenylate cyclase 2/0.444
3njoP2MAbscisic acid receptor PYR1/0.444
3olsESTEstrogen receptor beta/0.444
3sgy06WDihydrofolate reductase1.5.1.30.444
3tguWF3Cytochrome b/0.444
3u8hBHPPhospholipase A2, membrane associated/0.444
3zrbOR8Progesterone receptor/0.444
4bewACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.444
4bfpSWYTankyrase-22.4.2.300.444
4dk70KSOxysterols receptor LXR-beta/0.444
4fgrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.444
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
4i7fNVEGag-Pol polyprotein2.7.7.490.444
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.444
4kykIMNLactoylglutathione lyase4.4.1.50.444
4p6wMOFGlucocorticoid receptor/0.444
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.444
1cqsEQUSteroid Delta-isomerase5.3.3.10.443
1e2nRCAThymidine kinase/0.443
1g60SAMModification methylase MboII2.1.1.720.443
1gwrESTEstrogen receptor/0.443
1ikwEFZGag-Pol polyprotein2.7.7.490.443
1luqBTNStreptavidin/0.443
1mq0BRDCytidine deaminase3.5.4.50.443
1mznBM6Retinoic acid receptor RXR-alpha/0.443
1ot7IU5Bile acid receptor/0.443
1re0AFBADP-ribosylation factor 1/0.443
1re0AFBARF guanine-nucleotide exchange factor 1/0.443
1t7mDHTAndrogen receptor/0.443
1xq3R18Androgen receptor/0.443
1ygkRRCPyridoxal kinase2.7.1.350.443
2acwUPGGlycosyltransferase/0.443
2d06ESTSulfotransferase 1A12.8.2.10.443
2xk4OL2Serine/threonine-protein kinase Nek22.7.11.10.443
2zevB71Geranylgeranyl pyrophosphate synthase/0.443
3bfb9ODPheromone-binding protein ASP1/0.443
3bgrT27Gag-Pol polyprotein2.7.7.490.443
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3hziATPSerine/threonine-protein kinase toxin HipA/0.443
3i64DNA2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase/0.443
3ihgVAKAklavinone 12-hydroxylase RdmE/0.443
3lm4HPXCatechol 2,3-dioxygenase/0.443
3ql3FOLDihydrofolate reductase1.5.1.30.443
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.443
3rmeRMEAcidic mammalian chitinase3.2.1.140.443
3sqyQ11Dihydrofolate reductase1.5.1.30.443
3srwQ27Dihydrofolate reductase1.5.1.30.443
3tdaPN0Cytochrome P450 2D6/0.443
3tfq07MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3thrC2FGlycine N-methyltransferase2.1.1.200.443
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.443
4f0fACPProbable serine/threonine-protein kinase roco42.7.11.10.443
4fevPP1Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.443
4g1z0VPVitamin D3 receptor A/0.443
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.443
4j3mAJ8Tankyrase-22.4.2.300.443
4jtrIZPAldo-keto reductase family 1 member C2/0.443
4k88HFGBifunctional glutamate/proline--tRNA ligase6.1.1.150.443
4kfjFOLDihydrofolate reductase1.5.1.30.443
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.443
4ofrDHTAndrogen receptor/0.443
4v12POGMaoC like domain protein/0.443
1c7oPPGHemolysin/0.442
1cbrREACellular retinoic acid-binding protein 1/0.442
1dkfBMSRetinoic acid receptor alpha/0.442
1el4CTZObelin/0.442
1g50ESTEstrogen receptor/0.442
1hrvSDZGenome polyprotein/0.442
1n83CLRNuclear receptor ROR-alpha/0.442
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
1pd8CO4Dihydrofolate reductase1.5.1.30.442
1s9dAFBCytohesin-2/0.442
1s9dAFBADP-ribosylation factor 1/0.442
1t48BB3Tyrosine-protein phosphatase non-receptor type 13.1.3.480.442
1xiuREARetinoic acid receptor RXR/0.442
1xlsREARetinoic acid receptor RXR-alpha/0.442
1y9r1CAMineralocorticoid receptor/0.442
1yqj6NPMitogen-activated protein kinase 14/0.442
2aa5STRMineralocorticoid receptor/0.442
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.442
2ejuSAHtRNA (guanine(26)-N(2))-dimethyltransferase/0.442
2oh4GIGVascular endothelial growth factor receptor 22.7.10.10.442
2ol4JPNEnoyl-ACP reductase/0.442
2op18PCEnoyl-ACP reductase/0.442
2po7CHDFerrochelatase, mitochondrial4.99.1.10.442
2vqoTFGHistone deacetylase 43.5.1.980.442
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.442
3anmSYD1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.442
3ar7TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.442
3d4bDZDNAD-dependent protein deacetylase/0.442
3d7zGK5Mitogen-activated protein kinase 14/0.442
3dlgGWEGag-Pol polyprotein2.7.7.490.442
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3fy9XCFDihydrofolate reductase1.5.1.30.442
3h3qH13Collagen type IV alpha-3-binding protein/0.442
3hx3RETRetinaldehyde-binding protein 1/0.442
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3itzP66Mitogen-activated protein kinase 14/0.442
3l9hADPKinesin-like protein KIF11/0.442
3nxyD2HDihydrofolate reductase1.5.1.30.442
3t8xT8XT-cell surface glycoprotein CD1b/0.442
4af3VX6Aurora kinase B2.7.11.10.442
4b4w9L9Bifunctional protein FolD/0.442
4bfwZVWPantothenate kinase2.7.1.330.442
4cdmFO1Deoxyribodipyrimidine photolyase/0.442
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.442
4eos1ROCyclin-dependent kinase 22.7.11.220.442
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.442
4h1j0YHProtein-tyrosine kinase 2-beta2.7.10.20.442
4nbh9CATerminal oxygenase component of carbazole/0.442
4nmbFADBifunctional protein PutA/0.442
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.442
4y6gF6FTryptophan synthase alpha chain/0.442
5dx3ESTEstrogen receptor/0.442
5hbsRTLRetinol-binding protein 1/0.442
5il2SAHN6-adenosine-methyltransferase 70 kDa subunit/0.442
3reyXACAdenosine receptor A2a/0.442
1dggNDPCatalase1.11.1.60.441
1lhnAONSex hormone-binding globulin/0.441
1n3sGTPGTP cyclohydrolase 13.5.4.160.441
1p0pBCHCholinesterase3.1.1.80.441
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.441
1qjgEQUSteroid Delta-isomerase5.3.3.10.441
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.441
1srjNABStreptavidin/0.441
1w7h3IPMitogen-activated protein kinase 14/0.441
1xp9AIJEstrogen receptor/0.441
1z5uCMPClass B acid phosphatase/0.441
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.441
2g274LGRenin3.4.23.150.441
2q7iTESAndrogen receptor/0.441
2rehFADNitroalkane oxidase1.7.3.10.441
2rtrIMIStreptavidin/0.441
2xk85R1Serine/threonine-protein kinase Nek22.7.11.10.441
2yhdTESAndrogen receptor/0.441
3a1l2CCCytochrome P450/0.441
3aosJH2Hemolymph juvenile hormone binding protein/0.441
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.441
3qrtX14Cyclin-dependent kinase 22.7.11.220.441
3r6iJMSAldo-keto reductase family 1 member C3/0.441
3w8zHTKPutative FAD-dependent oxygenase EncM/0.441
3zk6H1IBcl-2-like protein 1/0.441
4a2jAS0Progesterone receptor/0.441
4a4l939Serine/threonine-protein kinase PLK12.7.11.210.441
4bgq38RCyclin-dependent kinase-like 52.7.11.220.441
4g210VPVitamin D3 receptor A/0.441
4h7zGUNQueuine tRNA-ribosyltransferase2.4.2.290.441
4jq3ZOMAldo-keto reductase family 1 member C2/0.441
4udaDEXMineralocorticoid receptor/0.441
5fd8A5APutative carboxypeptidase yocD/0.441
5mhtSAHModification methylase HhaI2.1.1.370.441
1hvyD16Thymidylate synthase2.1.1.450.440
1iiuRTLRetinol-binding protein 4/0.440
1nw6SFGModification methylase RsrI2.1.1.720.440
1rx5DDFDihydrofolate reductase1.5.1.30.440
1tgv5UDUridine phosphorylase2.4.2.30.440
1tkxGWBGag-Pol polyprotein2.7.7.490.440
1typNAPTrypanothione reductase1.8.1.120.440
1ux0THUCytidine deaminase3.5.4.50.440
1wc0APCAdenylate cyclase/0.440
1xpcAITEstrogen receptor/0.440
2ab2SNLMineralocorticoid receptor/0.440
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.440
2f2cAP9Cyclin-dependent kinase 62.7.11.220.440
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.440
2iziBTNStreptavidin/0.440
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
2owb626Serine/threonine-protein kinase PLK12.7.11.210.440
2pivDHTAndrogen receptor/0.440
2puiADPMethylthioribose kinase2.7.1.1000.440
2rtiGLLStreptavidin/0.440
2ykiYKIHeat shock protein HSP 90-alpha/0.440
2zlaVDBVitamin D3 receptor/0.440
3a60STURibosomal protein S6 kinase beta-12.7.11.10.440
3a783EVVitamin D3 receptor/0.440
3cr0809Wee1-like protein kinase2.7.10.20.440
3e5aVX6Aurora kinase A2.7.11.10.440
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.440
3n0z3ATAdenylate cyclase 2/0.440
3nefPYVAbscisic acid receptor PYL1/0.440
3nwlNDPCatalase1.11.1.60.440
3r43ID8Aldo-keto reductase family 1 member C3/0.440
3tptADPSerine/threonine-protein kinase toxin HipA/0.440
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.440
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
3vo30KFVascular endothelial growth factor receptor 22.7.10.10.440
3vruYS3Vitamin D3 receptor/0.440
3vt5YI2Vitamin D3 receptor/0.440
4a81DXCMajor pollen allergen Bet v 1-A/0.440
4bfuZVUPantothenate kinase2.7.1.330.440
4demYS4Farnesyl pyrophosphate synthase2.5.1.100.440
4dvq1CACytochrome P450 11B2, mitochondrial1.14.15.40.440
4ea0651Dehydrosqualene synthase/0.440
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.440
4g8zTOPDihydrofolate reductase1.5.1.30.440
4kaoKAOFocal adhesion kinase 12.7.10.20.440
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.440
4l5b1UXDeoxycytidine kinase2.7.1.740.440
4mryCEIObelin/0.440
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.440