sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1fkd | 818 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1fkd | 818 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 1.000 | |
| 2fke | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.823 | |
| 1fkj | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.696 | |
| 1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.665 | |
| 3o5r | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.643 | |
| 2dg3 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.639 | |
| 1c9h | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1B | 5.2.1.8 | 0.629 | |
| 4dh0 | MR8 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.626 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.624 | |
| 1bkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.623 | |
| 4dz2 | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.621 | |
| 1fkl | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.616 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.613 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.608 | |
| 1a7x | FKA | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.606 | |
| 1q6i | FK5 | FKBP-type peptidyl-prolyl cis-trans isomerase FkpA | 5.2.1.8 | 0.601 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.600 | |
| 2dg9 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.593 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.593 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.588 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.588 | |
| 1fki | SB1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.585 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.575 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.575 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.574 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.574 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.571 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.571 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.567 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.567 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.566 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.566 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.563 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.563 | |
| 4qt3 | RAP | Peptidylprolyl isomerase | / | 0.563 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.561 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.561 | |
| 4drp | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.561 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.560 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.559 | |
| 4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.558 | |
| 1fkh | SBX | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.553 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.551 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.546 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.546 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.540 | |
| 1j4h | SUB | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.539 | |
| 1fkg | SB3 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.535 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.535 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.512 | |
| 2gg3 | U13 | Methionine aminopeptidase | / | 0.507 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.505 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.502 | |
| 1oz0 | MS1 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.501 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.500 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.500 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.500 | |
| 3b4p | 3B4 | Phenazine biosynthesis protein A/B | / | 0.498 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.498 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.495 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.493 | |
| 4iif | CTS | Beta-glucosidase 1 | 3.2.1.21 | 0.493 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 1lbm | 137 | N-(5'-phosphoribosyl)anthranilate isomerase | 5.3.1.24 | 0.491 | |
| 4hn1 | TYD | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.490 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.489 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.488 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.488 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.487 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.487 | |
| 4e31 | JHZ | Methyltransferase | / | 0.487 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.486 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.486 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.486 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.486 | |
| 4d2d | ALA_ALA_ALA | Di-or tripeptide:H+ symporter | / | 0.486 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.486 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.486 | |
| 5dv2 | C5P | CCR4-NOT transcription complex subunit 6-like | 3.1.13.4 | 0.486 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.485 | |
| 2x3j | ATP | AcsD | / | 0.485 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.485 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.483 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.482 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.481 | |
| 2ggb | U17 | Methionine aminopeptidase | / | 0.480 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.480 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.480 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.478 | |
| 2gg8 | U15 | Methionine aminopeptidase | / | 0.478 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.478 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.478 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.478 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.478 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.478 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.477 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.477 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.476 | |
| 3d28 | B34 | Genome polyprotein | 2.7.7.48 | 0.476 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.476 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.476 | |
| 3u4o | 08E | Genome polyprotein | 2.7.7.48 | 0.475 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.474 | |
| 1vrq | FMN | Subunit alpha of sarocosine oxidase | / | 0.474 | |
| 1vrq | FMN | Subunit beta of sarcosine oxidase | / | 0.474 | |
| 1xuz | MMN | Capsule biosynthesis protein | / | 0.474 | |
| 3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.474 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.473 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 3g5i | DNB | Pyrimidine-specific ribonucleoside hydrolase RihA | / | 0.473 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.473 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.473 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.472 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.472 | |
| 3h59 | H59 | Genome polyprotein | 2.7.7.48 | 0.472 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.472 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.472 | |
| 5i2f | BS5 | Histidine triad nucleotide-binding protein 1 | 3 | 0.472 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.471 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.471 | |
| 3fvl | BHK | Carboxypeptidase A1 | 3.4.17.1 | 0.471 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 4xcz | T3Q | Qdtf | / | 0.471 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.470 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.470 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.470 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.470 | |
| 1m9n | AMZ | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.469 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.469 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.469 | |
| 4o30 | SAH | Probable Histone-lysine N-methyltransferase ATXR5 | 2.1.1.43 | 0.469 | |
| 1qvt | PRL | HTH-type transcriptional regulator QacR | / | 0.468 | |
| 2r8p | T6F | Transketolase 1 | / | 0.468 | |
| 3d27 | W29 | Methionine aminopeptidase | / | 0.468 | |
| 3i0o | SMI | Spectinomycin phosphotransferase | / | 0.468 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.468 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.468 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.468 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.468 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.468 | |
| 5c8d | 5AD | Probable transcriptional regulator | / | 0.468 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.468 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.467 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.467 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.467 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.467 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.467 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.467 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.466 | |
| 3iu8 | T03 | Methionine aminopeptidase 2 | / | 0.466 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.465 | |
| 1qs2 | NAD | Vip2Ac | / | 0.465 | |
| 2dxf | GNP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.465 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.465 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.465 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.465 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.465 | |
| 3vjk | M51 | Dipeptidyl peptidase 4 | / | 0.465 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.465 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.465 | |
| 4xd1 | T3Q | Qdtf | / | 0.465 | |
| 5c48 | URM | Histo-blood group ABO system transferase | / | 0.465 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.464 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.464 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.464 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.464 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.464 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.464 | |
| 1c7o | PPG | Hemolysin | / | 0.463 | |
| 1p4r | 354 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.463 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.463 | |
| 2evm | FC2 | Methionine aminopeptidase | / | 0.463 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.463 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.463 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.463 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.463 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.463 | |
| 3zgz | 84T | Leucine--tRNA ligase | / | 0.463 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.463 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.463 | |
| 1kia | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.462 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.462 | |
| 1w1v | ALJ | Chitinase | / | 0.462 | |
| 1x31 | FMN | Subunit alpha of sarocosine oxidase | / | 0.462 | |
| 1x31 | FMN | Subunit beta of sarcosine oxidase | / | 0.462 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.462 | |
| 2wcg | MT5 | Glucosylceramidase | 3.2.1.45 | 0.462 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.462 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.462 | |
| 4ikt | TFV | Methionine aminopeptidase 1 | / | 0.462 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.462 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.461 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.461 | |
| 1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.461 | |
| 1lke | DOG | Bilin-binding protein | / | 0.461 | |
| 1tg2 | H2B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.461 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.461 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.461 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.461 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.461 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.461 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 4xp4 | COC | Sodium-dependent dopamine transporter | / | 0.461 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.461 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.460 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.460 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.460 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.460 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.460 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2wzg | UPG | Uncharacterized protein | / | 0.460 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.460 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.460 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.460 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.460 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.460 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.459 | |
| 1i9c | 5AD | Glutamate mutase epsilon subunit | / | 0.459 | |
| 1jyw | 147 | Beta-galactosidase | 3.2.1.23 | 0.459 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.459 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.459 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.459 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2ejz | SAH | Diphthine synthase | / | 0.459 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.459 | |
| 2qs1 | UB1 | Glutamate receptor ionotropic, kainate 1 | / | 0.459 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.459 | |
| 3i97 | 8DR | Neuropilin-1 | / | 0.459 | |
| 3nh8 | DC2 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) | 3.5.1.114 | 0.459 | |
| 3tyc | XHP | Dihydropteroate synthase | / | 0.459 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.459 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.459 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.458 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.458 | |
| 2b1i | 93A | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.458 | |
| 2pid | YSA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.458 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.458 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.458 | |
| 3s2v | 3HU | Glutamate receptor ionotropic, kainate 1 | / | 0.458 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.458 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.458 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.457 | |
| 2gl0 | ADN | Uncharacterized protein | / | 0.457 | |
| 2rgu | 356 | Dipeptidyl peptidase 4 | / | 0.457 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.457 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.457 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.457 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.457 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.457 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.457 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.456 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.456 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.456 | |
| 3fx6 | BPX | Carboxypeptidase A1 | 3.4.17.1 | 0.456 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.456 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 4wxg | 2BO | Serine hydroxymethyltransferase | / | 0.456 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.455 | |
| 1rp7 | TZD | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.455 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2cv1 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.455 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.455 | |
| 2pja | 33Z | Carboxypeptidase B | / | 0.455 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 3udj | 092 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.455 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.455 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.454 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.454 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.454 | |
| 2fhk | MFN | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.454 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.454 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.454 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.454 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.454 | |
| 3e6e | DCS | Alanine racemase | / | 0.454 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.454 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.454 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.454 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 1qvu | PRL | HTH-type transcriptional regulator QacR | / | 0.453 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.453 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.453 | |
| 2wca | NP6 | O-GlcNAcase BT_4395 | / | 0.453 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.453 | |
| 3rth | RTH | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 4flj | Y08 | Methionine aminopeptidase 1 | / | 0.453 | |
| 4ikz | AFS | Di-tripeptide ABC transporter (Permease) | / | 0.453 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.453 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.453 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.452 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2gg0 | U11 | Methionine aminopeptidase | / | 0.452 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 3ccc | 7AC | Dipeptidyl peptidase 4 | / | 0.452 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.452 | |
| 4e2w | JHZ | Methyltransferase | / | 0.452 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.452 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.452 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.452 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.451 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.451 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.451 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.451 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.451 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.451 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.451 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.451 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.451 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4iah | 1DX | Alr2278 protein | / | 0.451 | |
| 4isu | IKM | Glutamate receptor 2 | / | 0.451 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 4lut | DCS | Alanine racemase | / | 0.451 | |
| 4rel | KMP | Glycosyltransferase | / | 0.451 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.451 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.450 | |
| 1pr0 | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.450 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.450 | |
| 1xh5 | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.450 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.450 | |
| 3t6i | NC8 | Endothiapepsin | 3.4.23.22 | 0.450 | |
| 3wag | TYD | Glycosyltransferase | / | 0.450 | |
| 4h0x | NAD | Iota toxin component Ia | / | 0.450 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.450 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.450 | |
| 5c8a | 5AD | Probable transcriptional regulator | / | 0.450 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.449 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.449 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.449 | |
| 1nue | GDP | Nucleoside diphosphate kinase B | 2.7.4.6 | 0.449 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.449 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1x2b | STX | Proline iminopeptidase | 3.4.11.5 | 0.449 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.449 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.449 | |
| 2r7n | ADP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase | / | 0.449 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.449 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.449 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.449 | |
| 4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.449 | |
| 4e32 | DWN | Methyltransferase | / | 0.449 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.449 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2b0q | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.448 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.448 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.448 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.448 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.448 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.448 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.447 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.447 | |
| 1jum | BER | HTH-type transcriptional regulator QacR | / | 0.447 | |
| 1njb | UMP | Thymidylate synthase | / | 0.447 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1zdw | FLV | Prenyltransferase | / | 0.447 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.447 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.447 | |
| 2ylx | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 3c8a | ARG_ARG_GLY_LEU_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.447 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.447 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.447 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.447 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.446 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.446 | |
| 2p99 | YE6 | Methionine aminopeptidase | / | 0.446 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.446 | |
| 2xwe | AMF | Glucosylceramidase | 3.2.1.45 | 0.446 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.446 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.446 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.446 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.446 | |
| 4kl1 | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.446 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.446 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.446 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 1e2n | RCA | Thymidine kinase | / | 0.445 | |
| 1hv9 | UD1 | Bifunctional protein GlmU | / | 0.445 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.445 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.445 | |
| 1xnz | FCD | Methionine aminopeptidase | / | 0.445 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.445 | |
| 2gg9 | U16 | Methionine aminopeptidase | / | 0.445 | |
| 2p98 | YE7 | Methionine aminopeptidase | / | 0.445 | |
| 2qs4 | LY5 | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 2uv0 | OHN | Transcriptional activator protein LasR | / | 0.445 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.445 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.445 | |
| 3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.445 | |
| 3v2u | ATP | Protein GAL3 | / | 0.445 | |
| 3zxi | TYA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.445 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.445 | |
| 4kq1 | U5P | Glycogen [starch] synthase | / | 0.445 | |
| 5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.445 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.445 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.444 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 1n75 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.444 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.444 | |
| 2v5u | FMN | Flavodoxin | / | 0.444 | |
| 2w03 | ADN | AcsD | / | 0.444 | |
| 2xjc | 5GP | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.444 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.444 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.444 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.444 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.444 | |
| 3pkc | Y08 | Methionine aminopeptidase 2 | / | 0.444 | |
| 3zki | WZV | Beta-secretase 2 | 3.4.23.45 | 0.444 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.444 | |
| 4e2x | TYD | Methyltransferase | / | 0.444 | |
| 4rtb | SAM | Putative thiazole biosynthesis protein ThiH | / | 0.444 | |
| 1c23 | MPH | Methionine aminopeptidase | / | 0.443 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.443 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.443 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.443 | |
| 3f6s | FMN | Flavodoxin | / | 0.443 | |
| 3g86 | T18 | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.443 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.443 | |
| 4d6q | PD2 | Lysine-specific demethylase 4D | 1.14.11 | 0.443 | |
| 4eqg | A5A | Histidine triad nucleotide-binding protein 1 | 3 | 0.443 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.443 | |
| 1a80 | NDP | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.442 | |
| 1el4 | CTZ | Obelin | / | 0.442 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.442 | |
| 1que | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 1th6 | OIN | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.442 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1z5u | CMP | Class B acid phosphatase | / | 0.442 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.442 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.442 | |
| 2cmo | M1L | Glutamate receptor 2 | / | 0.442 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.442 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.442 | |
| 2gg2 | U12 | Methionine aminopeptidase | / | 0.442 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.442 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.442 | |
| 3ivx | FG6 | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 3ksl | SZH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 3rzp | PRF | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.442 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.442 | |
| 4hai | I23 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.442 | |
| 4j7h | TRH | PCZA361.3 | / | 0.442 | |
| 4jnc | 1LF | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.442 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.442 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.442 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.442 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.441 | |
| 1wkg | POI | [LysW]-aminoadipate semialdehyde transaminase | / | 0.441 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.441 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.441 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.441 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.441 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.441 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.441 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 3n76 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.441 | |
| 4a1o | AMZ | Bifunctional purine biosynthesis protein PurH | 2.1.2.3 | 0.441 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4es5 | MGT | Polymerase basic protein 2 | / | 0.441 | |
| 4req | 5AD | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.441 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.441 | |
| 5brp | PNG | Glycoside Hydrolase Family 13 | / | 0.441 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.441 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.441 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.440 | |
| 2aj8 | SC3 | Dipeptidyl peptidase 4 | / | 0.440 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.440 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.440 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2x0y | X0T | O-GlcNAcase NagJ | / | 0.440 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.440 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.440 | |
| 3f90 | FMN | Flavodoxin | / | 0.440 | |
| 3g0c | RUF | Dipeptidyl peptidase 4 | / | 0.440 | |
| 3m4p | 4AD | Asparaginyl-tRNA synthetase, putative | / | 0.440 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.440 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.440 | |
| 4mk8 | 28Q | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 4mx1 | 1MX | Ricin | 3.2.2.22 | 0.440 | |
| 4phl | PIL | Phosphodiesterase | / | 0.440 | |
| 4x81 | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.440 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.440 |