sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3f2p | S3B | Thermolysin | 3.4.24.27 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3f2p | S3B | Thermolysin | 3.4.24.27 | 1.000 | |
| 3f28 | S7B | Thermolysin | 3.4.24.27 | 0.698 | |
| 3for | ZNP | Thermolysin | 3.4.24.27 | 0.657 | |
| 4h57 | 0PJ | Thermolysin | 3.4.24.27 | 0.656 | |
| 2tmn | 0FA | Thermolysin | 3.4.24.27 | 0.628 | |
| 6tmn | 0PI | Thermolysin | 3.4.24.27 | 0.611 | |
| 3fgd | BYA | Thermolysin | 3.4.24.27 | 0.602 | |
| 4tmn | 0PK | Thermolysin | 3.4.24.27 | 0.593 | |
| 1qf2 | TI3 | Thermolysin | 3.4.24.27 | 0.587 | |
| 4d9w | X32 | Thermolysin | 3.4.24.27 | 0.572 | |
| 3t8d | UBV | Thermolysin | 3.4.24.27 | 0.570 | |
| 3fvp | UB2 | Thermolysin | 3.4.24.27 | 0.557 | |
| 4tln | LNO | Thermolysin | 3.4.24.27 | 0.557 | |
| 3t8h | UBS | Thermolysin | 3.4.24.27 | 0.553 | |
| 3fv4 | 1U4 | Thermolysin | 3.4.24.27 | 0.537 | |
| 3t87 | UBZ | Thermolysin | 3.4.24.27 | 0.537 | |
| 3t74 | UBY | Thermolysin | 3.4.24.27 | 0.532 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.504 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.504 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.503 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.496 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.496 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.494 | |
| 5cvc | PLP | Serine racemase | / | 0.492 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.491 | |
| 4ifn | 12O | Kelch-like ECH-associated protein 1 | / | 0.491 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.490 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 3qus | AGS | Formate--tetrahydrofolate ligase | / | 0.485 | |
| 1qcw | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.483 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.483 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.483 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.483 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.482 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.482 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.481 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.481 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.481 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.480 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.480 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.480 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.480 | |
| 4xba | GMP | Aprataxin-like protein | 3 | 0.480 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.479 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.479 | |
| 4nmc | FAD | Bifunctional protein PutA | / | 0.479 | |
| 1v5y | 4HC | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.478 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.478 | |
| 4c35 | NU3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.478 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.478 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.477 | |
| 4rnx | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.477 | |
| 1f0y | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.476 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.476 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.476 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.476 | |
| 4d7m | TDC | Tetracycline repressor protein class D | / | 0.475 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.475 | |
| 1z6p | 194 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.474 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.474 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.474 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.473 | |
| 3jvv | ACP | Twitching mobility protein | / | 0.473 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.473 | |
| 1nmd | ATP | Major actin | / | 0.472 | |
| 4kc4 | WS3 | Histo-blood group ABO system transferase | / | 0.472 | |
| 4z54 | GDP | Neuronal-specific septin-3 | / | 0.472 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.471 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.471 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.471 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.471 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.471 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.471 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.471 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.470 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.470 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.470 | |
| 3hl4 | CDC | Choline-phosphate cytidylyltransferase A | / | 0.470 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.470 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.470 | |
| 4ho4 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.470 | |
| 4l8u | 9AZ | Serum albumin | / | 0.470 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.469 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.469 | |
| 3e8x | NAP | BH1520 protein | / | 0.469 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.469 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 4die | C5P | Cytidylate kinase | / | 0.469 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.469 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.468 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.468 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.468 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.468 | |
| 1orr | CDP | CDP-paratose 2-epimerase | / | 0.468 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.468 | |
| 3lnc | 5GP | Guanylate kinase | / | 0.468 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.468 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.468 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.468 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.467 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.467 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.467 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.467 | |
| 3i0a | DBH | Neutrophil gelatinase-associated lipocalin | / | 0.467 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 4okx | 198 | Androgen receptor | / | 0.467 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.466 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.466 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.466 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.466 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.466 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.465 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.465 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 4cfa | WOP | Integrase | / | 0.465 | |
| 1gox | FMN | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.464 | |
| 1wbt | WBT | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.464 | |
| 2jfz | 003 | Glutamate racemase | / | 0.464 | |
| 2qg4 | NAD | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.464 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 3w23 | 3RO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.464 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.464 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.464 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 2bf4 | NAP | NADPH--cytochrome P450 reductase | / | 0.463 | |
| 2c6c | 24I | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.463 | |
| 2cbr | A80 | Cellular retinoic acid-binding protein 1 | / | 0.463 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.463 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.462 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.462 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.462 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.462 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.462 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.461 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.461 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.461 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.461 | |
| 3pzc | COA | Amino acid--[acyl-carrier-protein] ligase 1 | 6.2.1.n2 | 0.461 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.461 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.461 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.461 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.461 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.460 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.460 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.460 | |
| 1vzb | UMP | Thymidylate synthase | / | 0.460 | |
| 2iyp | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.460 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
| 2ohv | NHL | Glutamate racemase | / | 0.460 | |
| 2pfg | DDD | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.460 | |
| 2wtk | ANP | STE20-related kinase adapter protein alpha | / | 0.460 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.460 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.460 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.460 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.460 | |
| 4nzo | ANP | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 | / | 0.460 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.460 | |
| 1fdi | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.459 | |
| 1zxc | IH6 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.459 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.459 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.459 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.459 | |
| 5c48 | URM | Histo-blood group ABO system transferase | / | 0.459 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.458 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.458 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.458 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.458 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.458 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.458 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.458 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.458 | |
| 1eio | GCH | Gastrotropin | / | 0.457 | |
| 1njf | ADP | DNA polymerase III subunit tau | 2.7.7.7 | 0.457 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.457 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.457 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.457 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.457 | |
| 4ema | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.457 | |
| 5k5z | ANP | Uncharacterized protein | / | 0.457 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.456 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.456 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.456 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.456 | |
| 3dsz | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.456 | |
| 3eo8 | FMN | Putative nitroreductase | / | 0.456 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.456 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.456 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.456 | |
| 4dpm | COA | Malonyl-CoA reductase | 1.2.1.75 | 0.456 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.456 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.456 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.455 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.455 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.455 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.455 | |
| 2e77 | FMN | Lactate oxidase | / | 0.455 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.455 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.455 | |
| 2oz0 | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.455 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.455 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.455 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.455 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.455 | |
| 3smk | CW7 | 14-3-3 protein sigma | / | 0.455 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.455 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.455 | |
| 4v2g | CTC | Tetracycline repressor protein class D | / | 0.455 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.455 | |
| 5fkl | TDC | Tetracycline repressor protein class D | / | 0.455 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.455 | |
| 1bxr | ANP | Carbamoyl-phosphate synthase large chain | / | 0.454 | |
| 1m2o | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.454 | |
| 1tww | HH2 | Dihydropteroate synthase | / | 0.454 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.454 | |
| 2nli | FMN | Lactate oxidase | / | 0.454 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.454 | |
| 2y3s | TIR | TamL | / | 0.454 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.454 | |
| 3w1t | WRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.454 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.454 | |
| 4eo3 | FMN | Bacterioferritin comigratory protein/NADH dehydrogenase | / | 0.454 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.454 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4jva | 1OR | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.454 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.454 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 4xmx | BES | Aminopeptidase N | 3.4.11.2 | 0.454 | |
| 1bux | PPS | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.453 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.453 | |
| 1n08 | ADP | Riboflavin kinase | 2.7.1.26 | 0.453 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.453 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.453 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.453 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.453 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.453 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.453 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.453 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.453 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.453 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 4e2b | FMN | Dehydrogenase | / | 0.453 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.453 | |
| 5aga | ANP | DNA polymerase theta | / | 0.453 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.453 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.452 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.452 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.452 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.452 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.452 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.452 | |
| 2yx6 | ADP | Uncharacterized protein | / | 0.452 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3l5b | BDO | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.452 | |
| 3x2w | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 3zkd | ANP | DNA gyrase subunit B | / | 0.452 | |
| 3zsr | O3N | Integrase | / | 0.452 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4cez | O3N | Integrase | / | 0.452 | |
| 4goj | GNP | ADP-ribosylation factor-like protein 3 | / | 0.452 | |
| 4hia | FMN | LOV protein | / | 0.452 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 4yp1 | 2BA | Stimulator of interferon genes protein | / | 0.452 | |
| 4yqf | GDP | Septin-9 | / | 0.452 | |
| 1bo4 | COA | Aminoglycoside-(3)-N-acetyltransferase | / | 0.451 | |
| 1jmg | UMP | Thymidylate synthase | / | 0.451 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.451 | |
| 1rjd | SAM | Leucine carboxyl methyltransferase 1 | 2.1.1.233 | 0.451 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1vfr | FMN | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.451 | |
| 2dsg | SAH | Diphthine synthase | / | 0.451 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.451 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.451 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.451 | |
| 2py7 | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.451 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2qll | PLP | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.451 | |
| 2wq6 | FAD | RE11660p | / | 0.451 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.451 | |
| 2xvq | 9DS | Serum albumin | / | 0.451 | |
| 2xw1 | 9NV | Serum albumin | / | 0.451 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.451 | |
| 3lu1 | UD2 | UDP-N-acetylglucosamine 4-epimerase | / | 0.451 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.451 | |
| 4h1m | 0YJ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.451 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4iax | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.451 | |
| 4nvk | 2NY | Peroxidase | / | 0.451 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.451 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.451 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.451 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.451 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.451 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1f20 | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.450 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.450 | |
| 1nqw | 5YL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.450 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.450 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.450 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.450 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.450 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.450 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3asj | XYN | Homoisocitrate dehydrogenase | / | 0.450 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.450 | |
| 3hf3 | FMN | Chromate reductase | / | 0.450 | |
| 3iog | SDF | Metallo-beta-lactamase type 2 | / | 0.450 | |
| 3qh2 | 3NM | Thiazole tautomerase | / | 0.450 | |
| 3v2u | ATP | Protein GAL3 | / | 0.450 | |
| 3x2u | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 3zsq | O4N | Integrase | / | 0.450 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.450 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.449 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.449 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.449 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.449 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.449 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.449 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.449 | |
| 1z48 | FMN | NADPH dehydrogenase | / | 0.449 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.449 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.449 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.449 | |
| 2j0s | ANP | Eukaryotic initiation factor 4A-III | 3.6.4.13 | 0.449 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.449 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.449 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.449 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.449 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.449 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.449 | |
| 3qcx | 3Q2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 4j7h | TRH | PCZA361.3 | / | 0.449 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.449 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.449 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.448 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 1nj6 | A5A | Proline--tRNA ligase | / | 0.448 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.448 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.448 | |
| 1yf8 | P6C | Beta-galactoside-specific lectin 4 | 3.2.2.22 | 0.448 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 2du2 | FMN | Lactate oxidase | / | 0.448 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.448 | |
| 2zfa | FMN | Lactate oxidase | / | 0.448 | |
| 3a4l | ANP | L-seryl-tRNA(Sec) kinase | 2.7.1.164 | 0.448 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.448 | |
| 3mje | NDP | AmphB | / | 0.448 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.448 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.448 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.448 | |
| 3w3o | ROE | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.448 | |
| 3x2v | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 3zsy | OM3 | Integrase | / | 0.448 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.448 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.448 | |
| 4rje | FNR | Lactate oxidase | / | 0.448 | |
| 4zr5 | RDF | Neprilysin | / | 0.448 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.447 | |
| 1c6y | MK1 | Protease | / | 0.447 | |
| 1f0y | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.447 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.447 | |
| 1nj5 | P5A | Proline--tRNA ligase | / | 0.447 | |
| 1o1v | TCH | Gastrotropin | / | 0.447 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.447 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.447 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.447 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.447 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.447 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.447 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.447 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.447 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.447 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.447 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.447 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3ppr | 4CS | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.447 | |
| 3tyc | XHP | Dihydropteroate synthase | / | 0.447 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.447 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.447 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.447 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.447 | |
| 4jic | FMN | GTN Reductase | / | 0.447 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.447 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.447 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.446 | |
| 1h72 | ANP | Homoserine kinase | 2.7.1.39 | 0.446 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 1oyc | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.446 | |
| 1snf | UMP | Deoxyuridine 5'-triphosphate nucleotidohydrolase | 3.6.1.23 | 0.446 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.446 | |
| 1xvt | COA | L-carnitine CoA-transferase | / | 0.446 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.446 | |
| 2olr | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.446 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.446 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3dt2 | GTP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.446 | |
| 3ix3 | OHN | Transcriptional activator protein LasR | / | 0.446 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.446 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.446 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
| 4hxy | NDP | Plm1 | / | 0.446 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.446 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.446 | |
| 4utl | FNR | Xenobiotic reductase | / | 0.446 | |
| 5ccy | TMP | Polymerase acidic protein | / | 0.446 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.446 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 5i4n | ATP | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 1fdr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.445 | |
| 1m76 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.445 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.445 | |
| 1tsl | A15 | Thymidylate synthase | / | 0.445 | |
| 1uay | ADN | Oxidoreductase | / | 0.445 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.445 | |
| 2bpo | NAP | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.445 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.445 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.445 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.445 | |
| 2yec | XQ0 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3au2 | DGT | DNA polymerase beta family (X family) | / | 0.445 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.445 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.445 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.445 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3iqg | ASN_TRP_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.445 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.445 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.445 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.445 | |
| 3nzp | PLP | Arginine decarboxylase | / | 0.445 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3r1r | ATP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.445 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4cgh | LOZ | Integrase | / | 0.445 | |
| 4de3 | DN8 | Beta-lactamase | / | 0.445 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.445 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.445 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.445 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.445 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.444 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.444 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1sxj | AGS | Replication factor C subunit 1 | / | 0.444 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.444 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.444 | |
| 1vza | UMP | Thymidylate synthase | / | 0.444 | |
| 1wbs | LI2 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.444 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.444 | |
| 2dxv | SAH | Diphthine synthase | / | 0.444 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.444 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.444 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.444 | |
| 3c1o | NAP | Eugenol synthase | / | 0.444 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.444 | |
| 3kmc | 403 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.444 | |
| 3lxp | IZA | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.444 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 3p0h | FSE | Putative tyrosyl-tRNA synthetase | / | 0.444 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 4cjr | FYM | Integrase | / | 0.444 | |
| 4ekk | ANP | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.444 | |
| 4kc2 | WS2 | Histo-blood group ABO system transferase | / | 0.444 | |
| 4l0s | 1UZ | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4loh | 1SY | Stimulator of interferon genes protein | / | 0.444 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.444 | |
| 5cku | NAP | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 5ebu | FMN | Lactate oxidase | / | 0.444 | |
| 5kjf | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1bdu | DUR | Thymidylate synthase | / | 0.443 | |
| 1fyf | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.443 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.443 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.443 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.443 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.443 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.443 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.443 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2fyp | RDE | Endoplasmin | / | 0.443 | |
| 3c15 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.443 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3eku | CY9 | Actin-5C | / | 0.443 | |
| 3gdv | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.443 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.443 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.443 | |
| 3srz | UPG | Toxin A | / | 0.443 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.443 | |
| 4cgg | K5Q | Integrase | / | 0.443 | |
| 4chy | C5Q | Integrase | / | 0.443 | |
| 4e2d | FMN | Dehydrogenase | / | 0.443 | |
| 4e93 | GUI | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.443 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4hmv | WUB | Phenazine biosynthesis protein PhzG | 1.4 | 0.443 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.443 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.443 | |
| 4zo3 | C6L | Acylhomoserine lactonase | / | 0.443 | |
| 1atn | ATP | Actin, alpha skeletal muscle | / | 0.442 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1fdo | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.442 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.442 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.442 | |
| 1rq1 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.442 | |
| 1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.442 | |
| 1wbv | LI3 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2e20 | B4P | Propionate kinase | / | 0.442 | |
| 2h8x | FMN | XenA | / | 0.442 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.442 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.442 | |
| 2q3k | MUW | Gag-Pol polyprotein | / | 0.442 | |
| 2vax | CSC | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.442 | |
| 2yww | ATP | Aspartate carbamoyltransferase regulatory chain | / | 0.442 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.442 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.442 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.442 | |
| 4ceo | G0T | Integrase | / | 0.442 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.442 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.442 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.442 | |
| 4hr2 | ADP | Nucleoside diphosphate kinase | / | 0.442 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.442 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.442 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.442 | |
| 4nu0 | AP5 | Adenylate kinase | / | 0.442 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.442 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.441 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1bwf | ATF | Glycerol kinase | / | 0.441 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.441 | |
| 1mx0 | ANP | Type 2 DNA topoisomerase 6 subunit B | / | 0.441 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.441 | |
| 1oo5 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.441 | |
| 1p0y | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.441 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.441 | |
| 1til | ATP | Anti-sigma F factor | / | 0.441 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.441 | |
| 2a8h | 4NH | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.441 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 2bb9 | AKC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.441 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.441 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.441 | |
| 2cts | COA | Citrate synthase, mitochondrial | 2.3.3.1 | 0.441 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.441 | |
| 2j6x | FMN | Lactate oxidase | / | 0.441 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.441 | |
| 3fui | 812 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.441 | |
| 3gf4 | UPG | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.441 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 3o15 | IFP | Thiamine-phosphate synthase | / | 0.441 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.441 | |
| 3zhy | FM6 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.441 | |
| 3zsw | ZSW | Integrase | / | 0.441 | |
| 4e09 | ACP | Plasmid partitioning protein ParF | / | 0.441 | |
| 4h0y | LAR | Actin, alpha skeletal muscle | / | 0.441 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.441 | |
| 4lez | 1SY | Cyclic GMP-AMP synthase | / | 0.441 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.441 | |
| 4y6u | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.441 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.441 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.440 | |
| 1c70 | L75 | Protease | / | 0.440 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.440 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.440 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.440 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.440 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1qg0 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.440 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.440 | |
| 1sln | INH | Stromelysin-1 | 3.4.24.17 | 0.440 | |
| 1t7k | BH0 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1xnj | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.440 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.440 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.440 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.440 | |
| 2oxn | OAN | Beta-hexosaminidase | / | 0.440 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.440 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 3elc | F01 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.440 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.440 | |
| 3ing | NDP | Homoserine dehydrogenase related protein | / | 0.440 | |
| 3lff | Z83 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3nh8 | DC2 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) | 3.5.1.114 | 0.440 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.440 | |
| 3rep | ATP | Integrin-linked protein kinase | 2.7.11.1 | 0.440 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.440 | |
| 4gtm | 7TM | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 4in4 | 4ID | Kelch-like ECH-associated protein 1 | / | 0.440 | |
| 4k7y | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.440 | |
| 4m2a | UPG | UDP-glucose pyrophosphorylase | / | 0.440 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.440 | |
| 4ng2 | OHN | Transcriptional activator protein LasR | / | 0.440 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.440 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.440 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.440 |