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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2yemWSHBromodomain-containing protein 4

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2yemWSHBromodomain-containing protein 4/1.000
4mr61K0Bromodomain-containing protein 2/0.613
4j1p1K0Bromodomain-containing protein 2/0.604
4mr51K0Bromodomain-containing protein 2/0.588
4bw39BMBromodomain-containing protein 4/0.587
4uyg73BBromodomain-containing protein 2/0.584
4bw2UTHBromodomain-containing protein 4/0.582
4flpJQ1Bromodomain testis-specific protein/0.578
4hxs1A3Bromodomain-containing protein 4/0.576
4o74R78Bromodomain-containing protein 4/0.575
4bjx73BBromodomain-containing protein 4/0.574
4a9oA9OBromodomain-containing protein 2/0.571
5bt52LOBromodomain-containing protein 2/0.569
4lrg1XBBromodomain-containing protein 4/0.568
4j0r1H2Bromodomain-containing protein 4/0.565
4aknS5BBromodomain-containing protein 2/0.563
4nqmY1ZBromodomain-containing protein 4/0.561
4ogiR78Bromodomain-containing protein 4/0.561
4j0s1H3Bromodomain-containing protein 4/0.560
4uyf73BBromodomain-containing protein 2/0.559
4a9nA9NBromodomain-containing protein 2/0.557
4lr61XABromodomain-containing protein 4/0.554
4mr41K0Bromodomain-containing protein 4/0.554
4men25KBromodomain-containing protein 4/0.553
4hxo1A6Bromodomain-containing protein 4/0.551
3zyu1GHBromodomain-containing protein 4/0.550
4c66H4CBromodomain-containing protein 4/0.548
4mep24YBromodomain-containing protein 4/0.545
4c67L5SBromodomain-containing protein 4/0.544
4bw1S5BBromodomain-containing protein 4/0.542
2yelWSHBromodomain-containing protein 4/0.538
4f3i0S6Bromodomain-containing protein 4/0.536
4j3i1K0Bromodomain-containing protein 4/0.536
4nr52LLCREB-binding protein/0.534
4qzsJQ1Bromodomain-containing protein 4/0.534
4alhA9PBromodomain-containing protein 2/0.529
4hxn1A7Bromodomain-containing protein 4/0.526
4gpj0Q1Bromodomain-containing protein 4/0.525
4hxr1A4Bromodomain-containing protein 4/0.524
4a9iP9IBromodomain-containing protein 2/0.523
2ydwWSHBromodomain-containing protein 2/0.522
4hby13FBromodomain-containing protein 4/0.522
2i40BLZCyclin-dependent kinase 22.7.11.220.520
4o71CPBBromodomain-containing protein 4/0.517
4alg1GHBromodomain-containing protein 2/0.516
4lyw21QBromodomain-containing protein 4/0.516
4ir5IR5Bromodomain adjacent to zinc finger domain protein 2B/0.510
3aqaBYHBromodomain-containing protein 2/0.504
4meq25OBromodomain-containing protein 4/0.503
4hbw14ZBromodomain-containing protein 4/0.500
2znq401Peroxisome proliferator-activated receptor delta/0.499
3nga3NGCasein kinase II subunit alpha2.7.11.10.499
2rhrEMOPutative ketoacyl reductase1.3.10.498
2yekEAMBromodomain-containing protein 2/0.495
4cfl8DQBromodomain-containing protein 4/0.495
4bw49B6Bromodomain-containing protein 4/0.494
4a9lP9LBromodomain-containing protein 4/0.492
1rdt570Peroxisome proliferator-activated receptor gamma/0.491
2znpK55Peroxisome proliferator-activated receptor delta/0.491
5bt42LOBromodomain-containing protein 4/0.491
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.490
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.490
3sn6P0GBeta-2 adrenergic receptor/0.490
4cfkLY2Bromodomain-containing protein 4/0.489
2r6jNDPEugenol synthase 11.1.1.3180.488
2w9hTOPDihydrofolate reductase1.5.1.30.487
3pe2E1BCasein kinase II subunit alpha2.7.11.10.487
4enhFVXCholesterol 24-hydroxylase/0.487
5dfcEAMBromodomain-containing protein 2/0.487
5eccNAPDehydrofolate reductase type I/0.486
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.485
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.485
4gk3L87Ephrin type-A receptor 32.7.10.10.485
2cchATPCyclin-dependent kinase 22.7.11.220.484
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.484
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.482
1m78NDPDihydrofolate reductase1.5.1.30.481
2oaxSNLMineralocorticoid receptor/0.480
3wffWFFMineralocorticoid receptor/0.480
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.480
5e8wSTUTGF-beta receptor type-12.7.11.300.480
5e8xSTUTGF-beta receptor type-12.7.11.300.480
1ndzFR5Adenosine deaminase3.5.4.40.479
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.479
3srqQ19Dihydrofolate reductase1.5.1.30.479
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.479
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.479
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.478
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.478
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.478
1s3uTQDDihydrofolate reductase1.5.1.30.477
3fwjCAMCamphor 5-monooxygenase1.14.15.10.477
3mtlFEFCyclin-dependent kinase 162.7.11.220.477
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.477
1di8DTQCyclin-dependent kinase 22.7.11.220.476
2v5aLZLBiotin carboxylase6.3.4.140.476
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.476
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.476
4o78SAVBromodomain-containing protein 4/0.476
2bkzSBCCyclin-dependent kinase 22.7.11.220.475
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.475
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.475
3kljFADNADH-rubredoxin oxidoreductase1.18.1.10.475
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.475
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.475
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.475
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.474
1phhFADp-hydroxybenzoate hydroxylase/0.474
1y0s331Peroxisome proliferator-activated receptor delta/0.474
2qboCAMCamphor 5-monooxygenase1.14.15.10.474
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.474
4cggK5QIntegrase/0.474
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.474
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.473
4fv7E94Mitogen-activated protein kinase 12.7.11.240.473
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.472
1pkdUCNCyclin-dependent kinase 22.7.11.220.472
1rjkVDZVitamin D3 receptor/0.472
2hckQUETyrosine-protein kinase HCK2.7.10.20.472
3sp9IL2Peroxisome proliferator-activated receptor delta/0.472
3t2zFADSulfide-quinone reductase/0.472
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.472
4gurFADLysine-specific histone demethylase 1B10.472
2zjwREFCasein kinase II subunit alpha2.7.11.10.471
3cgdCOACoenzyme A disulfide reductase/0.471
4ia3BIVVitamin D3 receptor A/0.471
1dz6CAMCamphor 5-monooxygenase1.14.15.10.470
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.470
1jkx138Phosphoribosylglycinamide formyltransferase/0.470
1w6hTITPlasmepsin-23.4.23.390.470
2pvkP45Casein kinase II subunit alpha2.7.11.10.470
2v58LZJBiotin carboxylase6.3.4.140.470
2wpa889Cyclin-dependent kinase 22.7.11.220.470
3h4vNAPPteridine reductase 11.5.1.330.470
3vruYS3Vitamin D3 receptor/0.470
4c62XWWTyrosine-protein kinase JAK2/0.470
4hgs15GCasein kinase I isoform gamma-32.7.11.10.470
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.470
1phgMYTCamphor 5-monooxygenase1.14.15.10.469
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.469
2ovhAS0Progesterone receptor/0.469
2zbaZBATrichothecene 3-O-acetyltransferase/0.469
3c3xNAPEugenol synthase 11.1.1.3180.469
3pxyJWSCyclin-dependent kinase 22.7.11.220.469
3rmf20ZCyclin-dependent kinase 22.7.11.220.469
3vt9YI4Vitamin D3 receptor/0.469
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.469
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.469
4fkr45KCyclin-dependent kinase 22.7.11.220.469
1eh4IC1Casein kinase I homolog 12.7.11.10.468
2qo9ANPEphrin type-A receptor 32.7.10.10.468
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.468
3ia4MTXDihydrofolate reductase/0.468
3up3XCAaceDAF-12/0.468
4a8v2ANMajor pollen allergen Bet v 1-J/0.468
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.468
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.468
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.468
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.467
2wihP48Cyclin-dependent kinase 22.7.11.220.467
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.467
4c02TAKActivin receptor type-12.7.11.300.467
4c9pCAMCytochrome P450/0.467
4l4xNDPAmphI/0.467
1zemNADXylitol dehydrogenase/0.466
2balPQAMitogen-activated protein kinase 14/0.466
2q8sL92Peroxisome proliferator-activated receptor gamma/0.466
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.466
3s7a684Dihydrofolate reductase1.5.1.30.466
3vjcZGASqualene synthase2.5.1.210.466
4g2rH1LProbable propionyl-CoA carboxylase beta chain 66.4.1.30.466
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.466
4mv8ACPBiotin carboxylase6.3.4.140.466
4nr82LLBromodomain-containing protein 4/0.466
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.466
1rx8FOLDihydrofolate reductase1.5.1.30.465
1vyw292Cyclin-dependent kinase 22.7.11.220.465
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.465
2vwx7X4Ephrin type-B receptor 42.7.10.10.465
3cgcCOACoenzyme A disulfide reductase/0.465
3eptFDAPutative FAD-monooxygenase/0.465
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.465
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.465
4b8zNAPGDP-L-fucose synthase1.1.1.2710.465
4g1z0VPVitamin D3 receptor A/0.465
4h4m494Gag-Pol polyprotein2.7.7.490.465
4hsuFADLysine-specific histone demethylase 1B10.465
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.465
2excJNKMitogen-activated protein kinase 102.7.11.240.464
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.464
2o4rVD5Vitamin D3 receptor/0.464
3sf6FDAGlutaryl-CoA dehydrogenase/0.464
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
4dpuAGSMevalonate diphosphate decarboxylase/0.464
4eor4SPCyclin-dependent kinase 22.7.11.220.464
4fko20KCyclin-dependent kinase 22.7.11.220.464
4rujVDXVitamin D3 receptor A/0.464
1fmlRTLRetinol dehydratase/0.463
1nq24HYThyroid hormone receptor beta/0.463
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.463
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.463
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.463
2p4yC03Peroxisome proliferator-activated receptor gamma/0.463
2r1rTTPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.463
2vwqNAPGlucose 1-dehydrogenase/0.463
3dr1C5DVitamin D3 receptor A/0.463
3fql79ZGenome polyprotein2.7.7.480.463
3oafOAGDihydrofolate reductase1.5.1.30.463
3rvg17PTyrosine-protein kinase JAK2/0.463
3t8vBTJM1 family aminopeptidase3.4.110.463
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.463
3w0jT08Vitamin D3 receptor/0.463
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.463
4b8wNAPGDP-L-fucose synthase1.1.1.2710.463
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
1ke9LS5Cyclin-dependent kinase 22.7.11.220.462
1pd9CO4Dihydrofolate reductase1.5.1.30.462
1rfuADPPyridoxal kinase2.7.1.350.462
1uyuCAMCamphor 5-monooxygenase1.14.15.10.462
2a4lRRCCyclin-dependent kinase 22.7.11.220.462
2fzhDH1Dihydrofolate reductase1.5.1.30.462
2o12FMNChorismate synthase/0.462
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.462
2xa4AZ5Tyrosine-protein kinase JAK2/0.462
2xneASHAurora kinase A2.7.11.10.462
3cukFADD-amino-acid oxidase1.4.3.30.462
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.462
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.462
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.462
4k771Q4Tyrosine-protein kinase JAK1/0.462
1cdeGARPhosphoribosylglycinamide formyltransferase/0.461
1qoqIGPTryptophan synthase alpha chain/0.461
1rw8580TGF-beta receptor type-12.7.11.300.461
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.461
2kceD16Thymidylate synthase/0.461
3ctj320Hepatocyte growth factor receptor2.7.10.10.461
4aotGW8Serine/threonine-protein kinase 102.7.11.10.461
4c58824Cyclin-G-associated kinase2.7.11.10.461
4eol1ROCyclin-dependent kinase 22.7.11.220.461
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.461
4g2fC07Ephrin type-A receptor 32.7.10.10.461
4iteTEYVitamin D3 receptor/0.461
4ure1PSCyclohexanol dehydrogenase/0.461
1a59COA2-methylcitrate synthase/0.460
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.460
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.460
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.460
2vr1ATFBiotin carboxylase6.3.4.140.460
3ibqATPPyridoxal kinase/0.460
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.460
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.460
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.460
4fks46KCyclin-dependent kinase 22.7.11.220.460
4nra2LWBromodomain adjacent to zinc finger domain protein 2B/0.460
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.460
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.460
1d7aAIRN5-carboxyaminoimidazole ribonucleotide mutase/0.459
1dkfBMSRetinoic acid receptor alpha/0.459
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.459
1py5PY1TGF-beta receptor type-12.7.11.300.459
1sowNADL-lactate dehydrogenase1.1.1.270.459
2a5kAZPReplicase polyprotein 1ab3.4.220.459
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.459
2q9fC3SCholesterol 24-hydroxylase/0.459
2qbmCAMCamphor 5-monooxygenase1.14.15.10.459
2y3rTRKTamL/0.459
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.459
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.459
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.459
3qt62P0Mevalonate diphosphate decarboxylase/0.459
3so9017Pol protein/0.459
3uli1N3Cyclin-dependent kinase 22.7.11.220.459
3w0hW12Vitamin D3 receptor/0.459
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.459
4fv8E63Mitogen-activated protein kinase 12.7.11.240.459
4looSB4Mitogen-activated protein kinase 14/0.459
4tuvCPZCytochrome P450 1191.140.459
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
5dp2NAPCurF/0.459
2rh1CAUBeta-2 adrenergic receptor/0.459
1aq1STUCyclin-dependent kinase 22.7.11.220.458
1bw9NADPhenylalanine dehydrogenase/0.458
2bakAQZMitogen-activated protein kinase 14/0.458
2bunFADAppA protein/0.458
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.458
2i1vADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.458
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.458
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.458
2uzdC85Cyclin-dependent kinase 22.7.11.220.458
2uzlC94Cyclin-dependent kinase 22.7.11.220.458
2v59LZKBiotin carboxylase6.3.4.140.458
2x7jTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.458
2x8hFADThioredoxin glutathione reductase/0.458
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.458
3ddw055Glycogen phosphorylase, liver form2.4.1.10.458
3t2kFADSulfide-quinone reductase/0.458
3v9v21LPeroxisome proliferator-activated receptor gamma/0.458
4a9yAQZMitogen-activated protein kinase 14/0.458
4fk8FADFerredoxin--NADP reductase/0.458
4fki09KCyclin-dependent kinase 22.7.11.220.458
4i8vBHFCytochrome P450 1A11.14.14.10.458
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
1mvsDTMDihydrofolate reductase1.5.1.30.457
2h96893Mitogen-activated protein kinase 82.7.11.240.457
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
2qbnCAMCamphor 5-monooxygenase1.14.15.10.457
2rhgIGPTryptophan synthase alpha chain/0.457
3bbrBHYGlutamate receptor 2/0.457
3gb4D3MDdmC/0.457
3h0a9RARetinoic acid receptor RXR-alpha/0.457
3mdmFJZCholesterol 24-hydroxylase/0.457
3oibFDAPutative acyl-CoA dehydrogenase/0.457
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.457
3vspEK8Peroxisome proliferator-activated receptor gamma/0.457
4fx360KCyclin-dependent kinase 22.7.11.220.457
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.457
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.457
4i22IREEpidermal growth factor receptor2.7.10.10.457
4ivb1J5Tyrosine-protein kinase JAK1/0.457
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.457
4wucANPDNA gyrase subunit B/0.457
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1ia1NDPDihydrofolate reductase1.5.1.30.456
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.456
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1rkhVD2Vitamin D3 receptor/0.456
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.456
1yw2PGJMitogen-activated protein kinase 14/0.456
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.456
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.456
3c6uM22Gag-Pol polyprotein2.7.7.490.456
3dlcSAMSAM (And some other nucleotide) binding motif:Generic methyltransferase/0.456
3qqgX06Cyclin-dependent kinase 22.7.11.220.456
3s1dZIRCytokinin dehydrogenase 11.5.99.120.456
3tnwF18Cyclin-dependent kinase 22.7.11.220.456
3w33W19Epidermal growth factor receptor2.7.10.10.456
4eji0QACytochrome P450 2A131.14.14.10.456
4fi1ATPCasein kinase II subunit alpha2.7.11.10.456
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.456
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.456
1h51FMNPentaerythritol tetranitrate reductase/0.455
1t88CAMCamphor 5-monooxygenase1.14.15.10.455
1xduSFGAclacinomycin 10-hydroxylase RdmB4.1.10.455
1zeoC01Peroxisome proliferator-activated receptor gamma/0.455
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.455
2w71L23Biotin carboxylase6.3.4.140.455
3freTOPDihydrofolate reductase1.5.1.30.455
3fwiCAMCamphor 5-monooxygenase1.14.15.10.455
4dh60KNBeta-secretase 13.4.23.460.455
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.455
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.455
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.455
1jtqLY3Thymidylate synthase/0.454
1ke6LS2Cyclin-dependent kinase 22.7.11.220.454
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.454
1txiTX5Vitamin D3 receptor/0.454
2a1nCAMCamphor 5-monooxygenase1.14.15.10.454
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.454
2b7aIZATyrosine-protein kinase JAK2/0.454
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.454
2xnbY8LCyclin-dependent kinase 22.7.11.220.454
3eyhIZATyrosine-protein kinase JAK1/0.454
3gwfFADCyclohexanone monooxygenase/0.454
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
3mdvCL6Cholesterol 24-hydroxylase/0.454
3nxxNDPDihydrofolate reductase1.5.1.30.454
3rnnRNNGlutamate receptor 2/0.454
3v9y24LPeroxisome proliferator-activated receptor gamma/0.454
3zh8C58Protein kinase C iota type2.7.11.130.454
4an4DUDPutative glycosyl transferase/0.454
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.454
4f9mFCMPeroxisome proliferator-activated receptor gamma/0.454
4nqnY1ZBromodomain-containing protein 9/0.454
4nyw2O3CREB-binding protein/0.454
4ruoBIVVitamin D3 receptor A/0.454
4y93746Tyrosine-protein kinase/0.454
1nqoNADGlyceraldehyde-3-phosphate dehydrogenase/0.453
1udaUFGUDP-glucose 4-epimerase5.1.3.20.453
2b1pAIZMitogen-activated protein kinase 102.7.11.240.453
2rh9IGPTryptophan synthase alpha chain/0.453
2vwz7X6Ephrin type-B receptor 42.7.10.10.453
3gxlQIGTGF-beta receptor type-12.7.11.300.453
3h6vNS6Glutamate receptor 2/0.453
3owaFADAcyl-CoA dehydrogenase/0.453
3pd2A3SThreonine--tRNA ligase6.1.1.30.453
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.453
3reoEUG(Iso)eugenol O-methyltransferase2.1.1.1460.453
3w0gW07Vitamin D3 receptor/0.453
4cf1IY7Integrase/0.453
4dgo0JWCasein kinase II subunit alpha2.7.11.10.453
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.453
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.453
4mwhATPCasein kinase II subunit alpha2.7.11.10.453
5dr6SKEAurora kinase A2.7.11.10.453
1q1rFADPutidaredoxin reductase1.18.1.50.452
1v1aKDG2-dehydro-3-deoxygluconokinase2.7.1.450.452
2ag0TPPBenzaldehyde lyase/0.452
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.452
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.452
2feuCAMCamphor 5-monooxygenase1.14.15.10.452
2xlsFADPutative flavin-containing monooxygenase/0.452
2y6o1N1Ephrin type-A receptor 42.7.10.10.452
3dolGWIPol protein/0.452
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.452
3lshFADPyranose 2-oxidase/0.452
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.452
3nj0PYVAbscisic acid receptor PYL2/0.452
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.452
3wrmCAMCamphor 5-monooxygenase1.14.15.10.452
4acm7YGCyclin-dependent kinase 22.7.11.220.452
4cfbOM3Integrase/0.452
4g1d0VKVitamin D3 receptor A/0.452
4ixgIXGDihydrofolate reductase1.5.1.30.452
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.452
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.452
4qnaX11Serine/threonine-protein kinase 242.7.11.10.452
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.452
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.452
1cm8ANPMitogen-activated protein kinase 12/0.451
1f4fTP3Thymidylate synthase/0.451
1fxsNAPGDP-L-fucose synthase/0.451
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.451
1wn3HXCPhenylacetic acid degradation protein PaaI/0.451
1xny191Propionyl-CoA carboxylase complex B subunit/0.451
1zrzBI1Protein kinase C iota type2.7.11.130.451
2aaxPDNMineralocorticoid receptor/0.451
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.451
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.451
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.451
2m56CAMCamphor 5-monooxygenase1.14.15.10.451
2po7CHDFerrochelatase, mitochondrial4.99.1.10.451
2w3vTOPDihydrofolate reductase/0.451
2wxvWXVCyclin-dependent kinase 22.7.11.220.451
2yee2ECHeat shock protein HSP 90-alpha/0.451
2yeiXQIHeat shock protein HSP 90-alpha/0.451
2ym2FADPhenylacetone monooxygenase1.14.13.920.451
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.451
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
3iok1P6Tyrosine-protein kinase JAK2/0.451
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.451
3t1a5MAGag-Pol polyprotein2.7.7.490.451
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.451
4cgiNZLIntegrase/0.451
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.451
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.451
4jr7GNPCasein kinase II subunit alpha2.7.11.10.451
4okt198Androgen receptor/0.451
4rvnCOAPhenylacetate-coenzyme A ligase/0.451
4xpdACON-terminal acetyltransferase A complex subunit NAT52.3.10.451
1c3eGARPhosphoribosylglycinamide formyltransferase/0.450
1drhNAPDihydrofolate reductase1.5.1.30.450
1gij2PUCyclin-dependent kinase 22.7.11.220.450
1iwiCAMCamphor 5-monooxygenase1.14.15.10.450
1y4lSVRBasic phospholipase A2 homolog 2/0.450
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.450
2dwbANPAurora kinase A2.7.11.10.450
2fypRDEEndoplasmin/0.450
2hamC33Vitamin D3 receptor/0.450
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.450
2ic3HBYGag-Pol polyprotein2.7.7.490.450
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.450
2rtoIMIStreptavidin/0.450
2wi72KLHeat shock protein HSP 90-alpha/0.450
3ac1KZITyrosine-protein kinase Lck2.7.10.20.450
3at4CCKCasein kinase II subunit alpha2.7.11.10.450
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
3fwfCAMCamphor 5-monooxygenase1.14.15.10.450
3gobHXXDdmC/0.450
3lqfNADGalactitol dehydrogenase/0.450
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.450
3ral04ZCyclin-dependent kinase 22.7.11.220.450
3w5rLOAVitamin D3 receptor/0.450
3wrjCAMCamphor 5-monooxygenase1.14.15.10.450
3zuyTCHTransporter/0.450
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
4cdmFO1Deoxyribodipyrimidine photolyase/0.450
4cgd8P3Integrase/0.450
4du82P0Mevalonate diphosphate decarboxylase/0.450
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.450
4ei40Q2Tyrosine-protein kinase JAK1/0.450
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.450
4jqeANPCasein kinase II subunit alpha2.7.11.10.450
4jxrACOAcetyltransferase/0.450
4lxhC1EAlpha/beta hydrolase fold/0.450
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.450
3qakUKAAdenosine receptor A2a/0.450
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1fvt106Cyclin-dependent kinase 22.7.11.220.449
1itzTPPTransketolase, chloroplastic2.2.1.10.449
1k6pXN3Gag-Pol polyprotein3.4.23.160.449
1p0hACOMycothiol acetyltransferase2.3.1.1890.449
1rszDIHPurine nucleoside phosphorylase2.4.2.10.449
1t85CAMCamphor 5-monooxygenase1.14.15.10.449
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.449
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.449
2bxmIMNSerum albumin/0.449
2eufLQQCyclin-dependent kinase 62.7.11.220.449
2rc6NAPFerredoxin--NADP reductase/0.449
2vbpVB1Isopenicillin N synthase1.21.3.10.449
2x7hPFNProstaglandin reductase 310.449
3bi2FADPolyamine oxidase FMS1/0.449
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.449
3cppCAMCamphor 5-monooxygenase1.14.15.10.449
3eo8FMNPutative nitroreductase/0.449
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.449
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.449
3lalKRVGag-Pol polyprotein2.7.7.490.449
3r9oZ71Cyclin-dependent kinase 22.7.11.220.449
3vt7VDXVitamin D3 receptor/0.449
3vt8YI3Vitamin D3 receptor/0.449
4a81DXCMajor pollen allergen Bet v 1-A/0.449
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.449
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.449
4fod0UVALK tyrosine kinase receptor2.7.10.10.449
4fqsLYAThymidylate synthase ThyA/0.449
4iva1J5Tyrosine-protein kinase JAK2/0.449
4ivd15TTyrosine-protein kinase JAK1/0.449
4lfiGNPCasein kinase II subunit alpha2.7.11.10.449
4lsl1YQGag-Pol polyprotein2.7.7.490.449
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.449
4u0mGTPCyclic GMP-AMP synthase/0.449
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.449
5fe112QHistone acetyltransferase KAT2B2.3.1.480.449
1cqp803Integrin alpha-L/0.448
1dz4CAMCamphor 5-monooxygenase1.14.15.10.448
1kziTHGThymidylate synthase/0.448
1oc1ASVIsopenicillin N synthase1.21.3.10.448
1pl8NADSorbitol dehydrogenase1.1.1.140.448
2cyeCOAPutative thioesterase/0.448
2h39ADQADP-glucose phosphorylase/0.448
2hb7O1CVitamin D3 receptor/0.448
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.448
2ow9SP6Collagenase 33.4.240.448
2qblCAMCamphor 5-monooxygenase1.14.15.10.448
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.448
2zuiCAMCamphor 5-monooxygenase1.14.15.10.448
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.448
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.448
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.448
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.448
3mtfA3FActivin receptor type-12.7.11.300.448
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.448
3p8jFMNPentaerythritol tetranitrate reductase/0.448
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.448
3vrwYS5Vitamin D3 receptor/0.448
3zewSTUEphrin type-B receptor 42.7.10.10.448
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.448
4awp99AHeat shock protein HSP 90-alpha/0.448
4bwxAGSPAB-dependent poly(A)-specific ribonuclease subunit pan3/0.448
4j6dTESCytochrome P450 monooxygenase/0.448
4ji91M3Tyrosine-protein kinase JAK2/0.448
4l49CAMCamphor 5-monooxygenase1.14.15.10.448
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.448
4loqSB4Mitogen-activated protein kinase 14/0.448
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
5cshATPCasein kinase II subunit alpha2.7.11.10.448
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.447
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.447
1ke5LS1Cyclin-dependent kinase 22.7.11.220.447
1rx1NAPDihydrofolate reductase1.5.1.30.447
1xddAAYIntegrin alpha-L/0.447
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2b53D23Cyclin-dependent kinase 22.7.11.220.447
2c3qGTXGlutathione S-transferase theta-12.5.1.180.447
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.447
2h94FADLysine-specific histone demethylase 1A10.447
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.447
2q46NAPUncharacterized protein At5g02240/0.447
2tpsTPSThiamine-phosphate synthase/0.447
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2x4f16XMyosin light chain kinase family member 42.7.11.10.447
2xyuQ9GEphrin type-A receptor 42.7.10.10.447
2z97CAMCamphor 5-monooxygenase1.14.15.10.447
3d84NDPDihydrofolate reductase1.5.1.30.447
3dhbC6LN-acyl homoserine lactonase AiiA3.1.1.810.447
3dleGFAGag-Pol polyprotein2.7.7.490.447
3eljGS7Mitogen-activated protein kinase 82.7.11.240.447
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.447
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.447
3qiyQI1Botulinum neurotoxin type A3.4.24.690.447
3r9uFADThioredoxin reductase/0.447
3rn8RN8Glutamate receptor 2/0.447
3s79ASDAromatase1.14.14.140.447
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4ax8ADPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.447
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.447
4e960NSBromodomain-containing protein 4/0.447
4eevL1XHepatocyte growth factor receptor2.7.10.10.447
4fhh0U3Vitamin D3 receptor A/0.447
4fkw62KCyclin-dependent kinase 22.7.11.220.447
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.447
4j6cSTRCytochrome P450 monooxygenase/0.447
4mcc21XtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.447
4ph9IBPProstaglandin G/H synthase 21.14.99.10.447
4y95746Tyrosine-protein kinase/0.447
4yryNADGlutamate synthase, beta subunit/0.447
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.447
5cb4ACPTubulin tyrosine ligase/0.447
5ctsCMCCitrate synthase, mitochondrial2.3.3.10.447
1cbqRE9Cellular retinoic acid-binding protein 2/0.446
1cerNADGlyceraldehyde-3-phosphate dehydrogenase/0.446
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1m2rMNYCasein kinase II subunit alpha2.7.11.10.446
1nooCAHCamphor 5-monooxygenase1.14.15.10.446
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.446
2bfyH1NAurora kinase B-A2.7.11.10.446
2g1n1IGRenin3.4.23.150.446
2ghlLIBMitogen-activated protein kinase 14/0.446
2hr8SAHDiphthine synthase/0.446
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.446
2jamJ60Calcium/calmodulin-dependent protein kinase type 1G2.7.11.170.446
2jih097A disintegrin and metalloproteinase with thrombospondin motifs 13.4.240.446
2vagV25Dual specificity protein kinase CLK12.7.12.10.446
2xvw9NRSerum albumin/0.446
2zlaVDBVitamin D3 receptor/0.446
3b9lAZZSerum albumin/0.446
3bptQUE3-hydroxyisobutyryl-CoA hydrolase, mitochondrial3.1.2.40.446
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3fhxPXLPyridoxal kinase2.7.1.350.446
3pj8404Cyclin-dependent kinase 22.7.11.220.446
3s00Z60Cyclin-dependent kinase 22.7.11.220.446
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.446
4ceqQCHIntegrase/0.446
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.446
4fkv61KCyclin-dependent kinase 22.7.11.220.446
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.446
4kb81QOCasein kinase I isoform delta2.7.11.10.446
4kl9NDPDihydrofolate reductase1.5.1.30.446
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.446
4qmpDKISerine/threonine-protein kinase 242.7.11.10.446
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.446
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.446
1dr2TAPDihydrofolate reductase1.5.1.30.445
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.445
1fwkADPHomoserine kinase2.7.1.390.445
1g6kNADGlucose 1-dehydrogenase1.1.1.470.445
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.445
1rk3VDXVitamin D3 receptor/0.445
1veaHBNHut operon positive regulatory protein/0.445
2abi1CAMineralocorticoid receptor/0.445
2bgiFADNADPH:ferredoxin reductase/0.445
2bhhRYUCyclin-dependent kinase 22.7.11.220.445
2dekSAHDiphthine synthase/0.445
2ociTYCValacyclovir hydrolase3.10.445
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.445
2qx7NAPEugenol synthase 11.1.1.3180.445
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.445
2vwpNDPGlucose 1-dehydrogenase/0.445
2wipP49Cyclin-dependent kinase 22.7.11.220.445
3akn11DFatty acid-binding protein, intestinal/0.445
3bvb017Gag-Pol polyprotein3.4.23.160.445
3dds26BGlycogen phosphorylase, liver form2.4.1.10.445
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3ii43IIDihydrolipoyl dehydrogenase1.8.1.40.445
3imgBZ3Pantothenate synthetase6.3.2.10.445
3lsiFADPyranose 2-oxidase/0.445
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.445
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.445
3rk507ZCyclin-dependent kinase 22.7.11.220.445
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.445
3tq9MTXDihydrofolate reductase/0.445
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.445
4bgg844Activin receptor type-12.7.11.300.445
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.445
4c2xNHWGlycylpeptide N-tetradecanoyltransferase 2/0.445
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.445
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.445
4l4dCAMCamphor 5-monooxygenase1.14.15.10.445
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.445
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.445
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.445
1ai9NDPDihydrofolate reductase1.5.1.30.444
1dr3TAPDihydrofolate reductase1.5.1.30.444
1eioGCHGastrotropin/0.444
1g5sI17Cyclin-dependent kinase 22.7.11.220.444
1ie8KH1Vitamin D3 receptor/0.444
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.444
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.444
1u0wSTLChalcone synthase 22.3.1.740.444
1u54ACPActivated CDC42 kinase 1/0.444
1v35NAIEnoyl-ACP reductase/0.444
1x8vESLLanosterol 14-alpha demethylase1.14.13.700.444
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.444
2b55D31Cyclin-dependent kinase 22.7.11.220.444
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.444
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.444
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.444
2dvlFADAcyl-CoA dehydrogenase/0.444
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.444
2gfdRDAEndoplasmin/0.444
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.444
2np8CC3Aurora kinase A2.7.11.10.444
2ovmAS0Progesterone receptor/0.444
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.444
2wotZZGTGF-beta receptor type-12.7.11.300.444
2xpuTDCTetracycline repressor protein class D/0.444
2znnS44Peroxisome proliferator-activated receptor alpha/0.444
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.444
3dokGWJPol protein/0.444
3il1B5DGlutamate receptor 2/0.444
3syiFADSulfide-quinone reductase/0.444
3wv7ADPHmd co-occurring protein HcgE/0.444
3zr7OR8Progesterone receptor/0.444
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4at0FADPossible succinate dehydrogenase/0.444
4cj54VWIntegrase/0.444
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4egnTWOCytochrome P450/0.444
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.444
4f650S9Fibroblast growth factor receptor 1/0.444
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.444
4hvi19STyrosine-protein kinase JAK32.7.10.20.444
4qa2SHHHistone deacetylase 83.5.1.980.444
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.444
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.444
4yuqKS1Calmodulin-like domain protein kinase/0.444
5bsrCOA4-coumarate--CoA ligase 26.2.1.120.444
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.444
3p0gP0GBeta-2 adrenergic receptor/0.444
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.443
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
1jpaANPEphrin type-B receptor 22.7.10.10.443
1k7l544Peroxisome proliferator-activated receptor alpha/0.443
1kqwRTLCellular retinol-binding protein type II/0.443
1m17AQ4Epidermal growth factor receptor2.7.10.10.443
1mjaCOAHistone acetyltransferase ESA1/0.443
1mvtDTMDihydrofolate reductase1.5.1.30.443
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.443
1tdrMTXDihydrofolate reductase1.5.1.30.443
1xelUPGUDP-glucose 4-epimerase5.1.3.20.443
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.443
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
2o0uC0MMitogen-activated protein kinase 102.7.11.240.443
2p20PRXAcetyl-coenzyme A synthetase/0.443
2tscCB3Thymidylate synthase/0.443
3adaNADSubunit alpha of sarocosine oxidase/0.443
3awhFMNFMN-binding protein/0.443
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3gw9VNILanosterol 14-alpha-demethylase/0.443
3h3sH15Collagen type IV alpha-3-binding protein/0.443
3l8p0CEAngiopoietin-1 receptor2.7.10.10.443
3mykANPMyosin-2 heavy chain/0.443
3owj1ELCasein kinase II subunit alpha2.7.11.10.443
3p3zP3ZPutative cytochrome P450/0.443
3q9zTXQCasein kinase II subunit alpha2.7.11.10.443
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.443
3t3q9PLCytochrome P450 2A61.14.130.443
3uleC69Actin-related protein 3/0.443
3vt5YI2Vitamin D3 receptor/0.443
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.443
4askK0ILysine-specific demethylase 6B1.14.110.443
4bcoT6QCyclin-dependent kinase 22.7.11.220.443
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.443
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.443
4g7gVFVLanosterol 14-alpha-demethylase/0.443
4gevCB3Thymidylate synthase/0.443
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.443
4ia7BIVVitamin D3 receptor A/0.443
4jajXU1Aurora kinase A2.7.11.10.443
4jqh1MFAlr2278 protein/0.443
4jucTPPBenzoylformate decarboxylase4.1.1.70.443
4ocvANPAminoglycoside phosphotransferase/0.443
4okx198Androgen receptor/0.443
4pkl1GHUncharacterized protein/0.443
4prvADPDNA gyrase subunit B/0.443
4wkqIREEpidermal growth factor receptor2.7.10.10.443
5fwnNAPPutative dehydrogenase/0.443
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.442
1og5SWFCytochrome P450 2C9/0.442
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.442
1sguMK1Gag-Pol polyprotein3.4.23.160.442
1sxjADPReplication factor C subunit 5/0.442
1t87CAMCamphor 5-monooxygenase1.14.15.10.442
1vjy460TGF-beta receptor type-12.7.11.300.442
2a3iC0RMineralocorticoid receptor/0.442
2c27ACOMycothiol acetyltransferase2.3.1.1890.442
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.442
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2ijmATPFocal adhesion kinase 12.7.10.20.442
2izuP01Casein kinase I isoform gamma-32.7.11.10.442
2x06NADL-sulfolactate dehydrogenase/0.442
2y6fM9FIsopenicillin N synthase1.21.3.10.442
2zb45OPProstaglandin reductase 21.3.1.480.442
3bg7FADPyranose 2-oxidase/0.442
3hl7I47Mitogen-activated protein kinase 14/0.442
3kfs3TLGag-Pol polyprotein/0.442
3lxiCAMCytochrome P450/0.442
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.442
3qtqX35Cyclin-dependent kinase 22.7.11.220.442
3rni21ZCyclin-dependent kinase 22.7.11.220.442
3sheI85MAP kinase-activated protein kinase 32.7.11.10.442
3tw6ADPPyruvate carboxylase/0.442
3ukoNADAlcohol dehydrogenase class-3/0.442
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.442
3vf80JETyrosine-protein kinase SYK2.7.10.20.442
3vjhJ35Peroxisome proliferator-activated receptor gamma/0.442
3vtbTKAVitamin D3 receptor/0.442
4asyN5YGlucose-1-phosphate thymidylyltransferase/0.442
4bfvZVVPantothenate kinase2.7.1.330.442
4bfxZVXPantothenate kinase2.7.1.330.442
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.442
4dc1NDPPutative ketoacyl reductase1.3.10.442
4eomATPCyclin-dependent kinase 22.7.11.220.442
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.442
4gk2L66Ephrin type-A receptor 32.7.10.10.442
4hy6FJ1Heat shock protein HSP 90-alpha/0.442
4iaq2GM5-hydroxytryptamine receptor 1B/0.442
4j6bPLOCytochrome P450 monooxygenase/0.442
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.442
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.442
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.442
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.442
4rrgA3TThreonine--tRNA ligase6.1.1.30.442
4yqfGDPSeptin-9/0.442
5dt0SKEAurora kinase A2.7.11.10.442
5esdTDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.442
5kgpACOPredicted acetyltransferase/0.442
1a8pFADFerredoxin--NADP reductase/0.441
1bwsNDPGDP-L-fucose synthase/0.441
1cscCMCCitrate synthase, mitochondrial2.3.3.10.441
1gebCAMCamphor 5-monooxygenase1.14.15.10.441
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
1k6tXN1Gag-Pol polyprotein3.4.23.160.441
1l4mNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.441
1nceCB3Thymidylate synthase/0.441
1o76CAMCamphor 5-monooxygenase1.14.15.10.441
1phePIYCamphor 5-monooxygenase1.14.15.10.441
1ppjANYCytochrome b/0.441
1pzfA3DLactate dehydrogenase/0.441
1v79FR7Adenosine deaminase3.5.4.40.441
1x8lOXRRetinol dehydratase/0.441
1y91CT9Cyclin-dependent kinase 22.7.11.220.441
1z6tADPApoptotic protease-activating factor 1/0.441
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
2e7zMGDAcetylene hydratase/0.441
2eleSAHDiphthine synthase/0.441
2fj1CTCTetracycline repressor protein class D/0.441
2gjlFMNNitronate monooxygenase1.13.12.160.441
2hcdBIVVitamin D3 receptor A/0.441
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.441
2nnpROCProtease/0.441
2vttLZDCyclin-dependent kinase 22.7.11.220.441
2zaxCAMCamphor 5-monooxygenase1.14.15.10.441
2zcePYLPyrrolysine--tRNA ligase/0.441
3a0iAJIGlucokinase2.7.1.20.441
3a783EVVitamin D3 receptor/0.441
3f03FMNPentaerythritol tetranitrate reductase/0.441
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3mneDEXGlucocorticoid receptor/0.441
3nwq2NCGag-Pol polyprotein3.4.23.160.441
3q33ACOHistone acetyltransferase RTT1092.3.1.480.441
3r8zZ63Cyclin-dependent kinase 22.7.11.220.441
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3w0c6DSVitamin D3 receptor/0.441
3wrhCAMCamphor 5-monooxygenase1.14.15.10.441
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.441
4ap3FADSteroid monooxygenase/0.441
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.441
4c9oCAMCytochrome P450/0.441
4df2FMNNADPH dehydrogenase/0.441
4emaBRLPeroxisome proliferator-activated receptor gamma/0.441
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.441
4g95OAGDihydrofolate reductase1.5.1.30.441
4jq8KJ8Epidermal growth factor receptor2.7.10.10.441
4l4bCAMCamphor 5-monooxygenase1.14.15.10.441
4oal245Cytokinin dehydrogenase 4/0.441
4qi7FADCellobiose dehydrogenase/0.441
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.441
4ux9ANPMitogen-activated protein kinase 82.7.11.240.441
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.441
1d3gBREDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.440
1diuBDMDihydrofolate reductase1.5.1.30.440
1e1xNW1Cyclin-dependent kinase 22.7.11.220.440
1h65GDPTranslocase of chloroplast 343.6.50.440
1njsKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.440
1nvtNAPShikimate dehydrogenase (NADP(+))/0.440
1osvCHCBile acid receptor/0.440
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.440
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1u8fNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.440
1xjjDGTVitamin B12-dependent ribonucleotide reductase/0.440
1xurPB5Collagenase 33.4.240.440
2aclREARetinoic acid receptor RXR-alpha/0.440
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.440
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.440
2iehMOYKinesin-like protein KIF11/0.440
2ittAEEEpidermal growth factor receptor2.7.10.10.440
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.440
2r3lSCWCyclin-dependent kinase 22.7.11.220.440
2uxiG50HTH-type transcriptional regulator TtgR/0.440
2v1aFMNNPH1-1/0.440
2xngA0HAurora kinase A2.7.11.10.440
2yac937Serine/threonine-protein kinase PLK12.7.11.210.440
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.440
2zdu446Mitogen-activated protein kinase 102.7.11.240.440
3ajrNADNDP-sugar epimerase/0.440
3bhtMFRCyclin-dependent kinase 22.7.11.220.440
3cbsR12Cellular retinoic acid-binding protein 2/0.440
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3jzfJZKBiotin carboxylase6.3.4.140.440
3k4nFADPyranose 2-oxidase/0.440
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.440
3nksACJProtoporphyrinogen oxidase1.3.3.40.440
3nxe2NCProtease/0.440
3ttjJBIMitogen-activated protein kinase 102.7.11.240.440
3zhyFM61-deoxy-D-xylulose 5-phosphate reductoisomerase/0.440
4a2jAS0Progesterone receptor/0.440
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.440
4apuA2KProgesterone receptor/0.440
4bb432WEphrin type-B receptor 42.7.10.10.440
4fxy0W2Neurolysin, mitochondrial3.4.24.160.440
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440
4iah1DXAlr2278 protein/0.440
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.440
4jjiNADAlcohol dehydrogenase class-3/0.440
4k9oTPPBenzoylformate decarboxylase4.1.1.70.440
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.440
4lrjANPUncharacterized protein/0.440
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.440
4qa0SHHHistone deacetylase 83.5.1.980.440
4qi5FADCellobiose dehydrogenase/0.440
4rupH97Vitamin D3 receptor A/0.440
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.440
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.440
5li5THR_ALA_ASN_PRO_SEPKLTH0G14146p/0.440
3emlZMAAdenosine receptor A2a/0.440