sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	tRNA (guanine-N(1)-)-methyltransferase
ID:	TRMD_HAEIN
AC:	P43912
Organism:	Haemophilus influenzae
Reign:	Bacteria
TaxID:	71421
EC Number:	2.1.1.228

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Chains:

Chain Name:	Percentage of Residues within binding site
A	89 %
B	11 %

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Ligand binding site composition:

B-Factor:	30.482
Number of residues:	29
Including
Standard Amino Acids:	28
Non Standard Amino Acids:	0
Water Molecules:	1
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
1.134	914.625

% Hydrophobic	% Polar
46.49	53.51
According to VolSite

HET Code:	21X
Formula:	C15H15N4O2S
Molecular weight:	315.370 g/mol
DrugBank ID:	-
Buried Surface Area:	66.6 %
Polar Surface area:	126.43 Å2

Number of
H-Bond Acceptors:	3
H-Bond Donors:	3
Rings:	3
Aromatic rings:	2
Anionic atoms:	0
Cationic atoms:	1
Rule of Five Violation:	0
Rotatable Bonds:	4

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Mass center Coordinates

X	Y	Z
22.2185	42.6479	-1.556

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