sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2iyg | FMN | AppA, antirepressor of ppsR, sensor of blue light |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2iyg | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 1.000 | |
| 1yrx | FMN | AppA protein | / | 0.647 | |
| 4hh0 | FMN | AppA protein | / | 0.587 | |
| 1x0p | FAD | Tll0078 protein | / | 0.558 | |
| 4yus | FMN | Family 3 adenylate cyclase | / | 0.532 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.525 | |
| 2iyi | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.521 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.515 | |
| 3gfz | FMN | Uncharacterized protein | / | 0.513 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.511 | |
| 2byc | FMN | Blue-light receptor of the BLUF-family | / | 0.510 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.508 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.508 | |
| 3gg0 | FMN | Uncharacterized protein | / | 0.507 | |
| 3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.507 | |
| 4yut | FMN | Family 3 adenylate cyclase | / | 0.505 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.503 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.503 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.502 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.501 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.500 | |
| 3gfx | FMN | Uncharacterized protein | / | 0.499 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.498 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.498 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.497 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.496 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.496 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.495 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.495 | |
| 4okw | 198 | Androgen receptor | / | 0.495 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.494 | |
| 1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.493 | |
| 2pmn | K51 | Protein kinase 7 | / | 0.493 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.492 | |
| 4ct1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.492 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.491 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.491 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.490 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.490 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.489 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.489 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.488 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.487 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.487 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.486 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.485 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.485 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.484 | |
| 3gfy | FMN | Uncharacterized protein | / | 0.483 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.483 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.483 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.483 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.482 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.482 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.482 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.481 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.481 | |
| 2bxq | IMN | Serum albumin | / | 0.481 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.481 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.480 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.480 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.480 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.479 | |
| 1osv | CHC | Bile acid receptor | / | 0.479 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.479 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.478 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.478 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.478 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.478 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.478 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.478 | |
| 1u26 | IHS | Myo-inositol hexaphosphate phosphohydrolase | / | 0.477 | |
| 1f28 | UMP | Thymidylate synthase | 2.1.1.45 | 0.476 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.476 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.476 | |
| 4ftq | 4HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.476 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.475 | |
| 3ua3 | SAH | Protein arginine N-methyltransferase 5 | / | 0.475 | |
| 1uvr | BI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.474 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 2f02 | ATP | Tagatose-6-phosphate kinase | / | 0.474 | |
| 2ibz | UQ6 | Cytochrome b | / | 0.474 | |
| 2wmv | ZYV | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.474 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 2hfn | FMN | Activator of photopigment and puc expression | / | 0.473 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
| 2wms | ZYS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.473 | |
| 4b5b | BBE | Glucose-1-phosphate thymidylyltransferase | / | 0.473 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.472 | |
| 1um0 | FMN | Chorismate synthase | / | 0.472 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.472 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
| 3b9l | AZZ | Serum albumin | / | 0.472 | |
| 3dol | GWI | Pol protein | / | 0.472 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.472 | |
| 3s8a | DGT | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.472 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.471 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.471 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.471 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 3gg1 | FMN | Uncharacterized protein | / | 0.471 | |
| 3lm9 | ADP | Putative fructokinase | 2.7.1.4 | 0.471 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.471 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.471 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.471 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.471 | |
| 1yin | CM3 | Estrogen receptor | / | 0.470 | |
| 2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.470 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.470 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.470 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.470 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.470 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.470 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.470 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.470 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.469 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.469 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.469 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.469 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4ej4 | EJ4 | Delta-type opioid receptor | / | 0.469 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.468 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.468 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2ym3 | YM3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.468 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.468 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.467 | |
| 2wec | PP5 | Penicillopepsin-1 | 3.4.23.20 | 0.467 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.467 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.467 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.467 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.466 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.466 | |
| 1yp4 | ADQ | Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic | 2.7.7.27 | 0.466 | |
| 2cvv | ANP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.466 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.466 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.466 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3nta | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.466 | |
| 4b42 | 942 | Glucose-1-phosphate thymidylyltransferase | / | 0.466 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.465 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.465 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.465 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.465 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.465 | |
| 2rto | IMI | Streptavidin | / | 0.465 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.465 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.465 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.465 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.465 | |
| 4a9r | RU5 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.465 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.465 | |
| 1g0r | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.464 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.464 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.464 | |
| 2vwp | NDP | Glucose 1-dehydrogenase | / | 0.464 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.464 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.464 | |
| 2xvv | 9DN | Serum albumin | / | 0.464 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.464 | |
| 3nuy | JPZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.464 | |
| 4cvl | ACP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.464 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.464 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.464 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.463 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.463 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 3s8c | ANP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.463 | |
| 4e0i | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.463 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.463 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.462 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.462 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.462 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.462 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.462 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 4rd2 | GNP | Translation initiation factor 2 subunit gamma | / | 0.462 | |
| 1mbt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.461 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.461 | |
| 2q5o | PPY | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.461 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.461 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.461 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.461 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3k8t | DGT | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.461 | |
| 3rsr | N5P | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.461 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.461 | |
| 4cje | Q31 | Integrase | / | 0.461 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.461 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.460 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.460 | |
| 2cvw | TTP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.460 | |
| 2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.460 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 2ym8 | YM8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.460 | |
| 4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.460 | |
| 4ceq | QCH | Integrase | / | 0.460 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.460 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.460 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.460 | |
| 4okx | 198 | Androgen receptor | / | 0.460 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.460 | |
| 4yqf | GDP | Septin-9 | / | 0.460 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.459 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.459 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.459 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.459 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.459 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.459 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.459 | |
| 3eej | 53R | Uncharacterized protein | / | 0.459 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.459 | |
| 4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 4dh5 | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 4gfv | PRO_GLU_LEU_THR_PTR | Tyrosine-protein phosphatase non-receptor type 18 | 3.1.3.48 | 0.459 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.459 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.458 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.458 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 1kbj | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.458 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.458 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.458 | |
| 2b5v | NAP | Glucose 1-dehydrogenase | / | 0.458 | |
| 2bxm | IMN | Serum albumin | / | 0.458 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.458 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.458 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.458 | |
| 3m6p | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.458 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.458 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.458 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.458 | |
| 4ieb | ANP | Calmodulin-domain protein kinase 1 | / | 0.458 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.458 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.457 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.457 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.457 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 2x2k | X2K | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.457 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 3gon | ANP | Phosphomevalonate kinase | / | 0.457 | |
| 3vqh | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.457 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.457 | |
| 4u7w | NDP | MxaA | / | 0.457 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.457 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.456 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 1rkd | ADP | Ribokinase | / | 0.456 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.456 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.456 | |
| 1u33 | LM2 | Pancreatic alpha-amylase | / | 0.456 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.456 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2cvu | ANP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.456 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.456 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.456 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.456 | |
| 2xvw | 9NR | Serum albumin | / | 0.456 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.456 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 3qcx | 3Q2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.456 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.455 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.455 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 1pzf | A3D | Lactate dehydrogenase | / | 0.455 | |
| 1t7j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 1u30 | GOX | Pancreatic alpha-amylase | / | 0.455 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.455 | |
| 3anx | MTA | Polyamine aminopropyltransferase | / | 0.455 | |
| 3p0j | TYE | Putative tyrosyl-tRNA synthetase | / | 0.455 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.455 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.455 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.455 | |
| 4cj3 | E4F | Integrase | / | 0.455 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4n57 | ADP | APH(2'')-Id | / | 0.455 | |
| 4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.455 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.455 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.454 | |
| 1c70 | L75 | Protease | / | 0.454 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.454 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.454 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.454 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.454 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.454 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.454 | |
| 1v0o | INR | Cell division control protein 2 homolog | 2.7.11.22 | 0.454 | |
| 2e83 | FMN | FMN-binding protein | / | 0.454 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.454 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.454 | |
| 2zh6 | ATP | CCA-adding enzyme | 2.7.7.72 | 0.454 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 3n4m | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.454 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.454 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.454 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.454 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.454 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.454 | |
| 4g8b | HL6 | Alpha/beta hydrolase fold protein | / | 0.454 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.454 | |
| 4k41 | ATP | Actin, alpha skeletal muscle | / | 0.454 | |
| 4n49 | MGT | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 | 2.1.1.57 | 0.454 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.454 | |
| 1bwb | 146 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1ckp | PVB | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.453 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.453 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.453 | |
| 1svm | ATP | Large T antigen | 3.6.4 | 0.453 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.453 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.453 | |
| 2pzi | AXX | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.453 | |
| 2wky | IBC | Glutamate receptor ionotropic, kainate 1 | / | 0.453 | |
| 2wmr | ZYR | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2wou | ZZF | TGF-beta receptor type-1 | 2.7.11.30 | 0.453 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.453 | |
| 3pp1 | IZG | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.453 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.453 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4e8w | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.453 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.453 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4k77 | 1Q4 | Tyrosine-protein kinase JAK1 | / | 0.453 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.453 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.453 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.452 | |
| 1e80 | 0GQ | Endothiapepsin | 3.4.23.22 | 0.452 | |
| 1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.452 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.452 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.452 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2gtm | LID | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.452 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.452 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.452 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.452 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.452 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.452 | |
| 3zra | ORB | Progesterone receptor | / | 0.452 | |
| 4fkq | 42K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.452 | |
| 4kwh | NAP | Reductase homolog | / | 0.452 | |
| 4o0s | ADN | Aurora kinase A | 2.7.11.1 | 0.452 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.452 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.451 | |
| 1hmp | 5GP | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.451 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.451 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.451 | |
| 2e5a | LAQ | Lipoyltransferase 1, mitochondrial | 2.3.1 | 0.451 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2rgx | AP5 | Adenylate kinase | / | 0.451 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.451 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 2wmw | ZYW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.451 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.451 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.451 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3qcq | 3Q0 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 3tij | URI | Nucleoside permease | / | 0.451 | |
| 3vi5 | M4M | Hematopoietic prostaglandin D synthase | / | 0.451 | |
| 4cfa | WOP | Integrase | / | 0.451 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.451 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 4dxd | 9PC | Cell division protein FtsZ | / | 0.451 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.451 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.451 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 5f8f | SFG | Possible transcriptional regulatory protein | / | 0.451 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.450 | |
| 1nf7 | RVP | Inosine-5'-monophosphate dehydrogenase 2 | / | 0.450 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.450 | |
| 1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.450 | |
| 1qf5 | RPL | Adenylosuccinate synthetase | / | 0.450 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.450 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.450 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.450 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 2q5o | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.450 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.450 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.450 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.450 | |
| 3rpo | 24Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 3zt1 | OM1 | Integrase | / | 0.450 | |
| 4a9t | A9T | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.450 | |
| 4gub | 0Y4 | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 4ku3 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.450 | |
| 4nt0 | 3DU | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.450 | |
| 5aun | ADP | Iron-sulfur cluster carrier protein | / | 0.450 | |
| 5e6y | ACX | 1,4-alpha-glucan branching enzyme GlgB | / | 0.450 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.449 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.449 | |
| 1x14 | NAD | NAD(P) transhydrogenase subunit alpha | 1.6.1.2 | 0.449 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.449 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2bun | FAD | AppA protein | / | 0.449 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2pml | ANP | Uncharacterized protein | / | 0.449 | |
| 2qn7 | HBZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.449 | |
| 2rti | GLL | Streptavidin | / | 0.449 | |
| 2xau | ADP | Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 | 3.6.4.13 | 0.449 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.449 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.449 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.449 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.449 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.449 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.449 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.449 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.449 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.449 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 4cgj | NZL | Integrase | / | 0.449 | |
| 4iae | 1DX | Alr2278 protein | / | 0.449 | |
| 4iah | 1DX | Alr2278 protein | / | 0.449 | |
| 4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.449 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.449 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.449 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.449 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.449 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.448 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.448 | |
| 1u1i | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.448 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.448 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.448 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.448 | |
| 2izt | 23D | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.448 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 2r9k | SGI | Beta-galactoside-specific lectin 1 | / | 0.448 | |
| 2tys | PLT | Tryptophan synthase beta chain | 4.2.1.20 | 0.448 | |
| 2ywv | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | / | 0.448 | |
| 3c16 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.448 | |
| 3dok | GWJ | Pol protein | / | 0.448 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.448 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3py0 | SU9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3rn8 | RN8 | Glutamate receptor 2 | / | 0.448 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.448 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.448 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4eu5 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.448 | |
| 4f70 | 0ST | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.448 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.448 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.448 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.448 | |
| 4k6z | 1Q3 | Tyrosine-protein kinase JAK1 | / | 0.448 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.448 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.448 | |
| 4r8h | SP1 | cAMP-activated global transcriptional regulator CRP | / | 0.448 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.447 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1g28 | FMN | PHY3 | / | 0.447 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.447 | |
| 1qy5 | NEC | Endoplasmin | / | 0.447 | |
| 1zoy | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.447 | |
| 1zoy | UQ1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.447 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.447 | |
| 2bl4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.447 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2gcq | DOI | Adenylosuccinate synthetase | / | 0.447 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.447 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.447 | |
| 2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2xf0 | 4UB | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2zv9 | PP2 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.447 | |
| 3bgc | LJH | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.447 | |
| 3iaa | TYD | CalG2 | / | 0.447 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.447 | |
| 3oht | 1N1 | Mitogen-activated protein kinase | / | 0.447 | |
| 3ova | APC | CCA-adding enzyme | 2.7.7.72 | 0.447 | |
| 3ovb | ATP | CCA-adding enzyme | 2.7.7.72 | 0.447 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.447 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3tb9 | ANP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.447 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.447 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 5hq8 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.447 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.447 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.446 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.446 | |
| 1efp | FAD | Electron transfer flavoprotein subunit alpha | / | 0.446 | |
| 1ez0 | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.446 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.446 | |
| 1pxm | CK5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1q19 | SSC | Carbapenam-3-carboxylate synthase | 6.3.3.6 | 0.446 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1tys | TMP | Thymidylate synthase | / | 0.446 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.446 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.446 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.446 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.446 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.446 | |
| 2of2 | 547 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.446 | |
| 2qtg | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1 | 3.2.2.9 | 0.446 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.446 | |
| 2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.446 | |
| 2wti | WTI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.446 | |
| 2xuu | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 2ynh | EUR | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.446 | |
| 2zm1 | KSF | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.446 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.446 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.446 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.446 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.446 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3tba | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.446 | |
| 3u2m | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.446 | |
| 3vri | 1KX | HLA class I histocompatibility antigen, B-57 alpha chain | / | 0.446 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.446 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.446 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.446 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.446 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.446 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.446 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.446 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.446 | |
| 1c6x | 3IN | Protease | / | 0.445 | |
| 1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.445 | |
| 1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.445 | |
| 1u3w | FXY | Alcohol dehydrogenase 1C | 1.1.1.1 | 0.445 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.445 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.445 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 2c3c | NAP | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.445 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2fto | TMP | Thymidylate synthase | / | 0.445 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.445 | |
| 2hnd | NVP | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 2imp | NAI | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.445 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.445 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.445 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.445 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.445 | |
| 3ac5 | KZM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 3cwk | REA | Cellular retinoic acid-binding protein 2 | / | 0.445 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.445 | |
| 3e01 | PZ2 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3g2h | KOT | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.445 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.445 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3nj8 | NJ8 | Enoyl-acyl carrier reductase | / | 0.445 | |
| 3r7u | X96 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3s87 | DGT | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.445 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 3w55 | 1FM | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.445 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4dta | ADN | APH(2'')-Id | / | 0.445 | |
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 0.445 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4fvr | ATP | Tyrosine-protein kinase JAK2 | / | 0.445 | |
| 4j54 | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.445 | |
| 5a3b | APR | SIR2 family protein | / | 0.445 | |
| 5alu | HD2 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.445 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.444 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.444 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.444 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.444 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.444 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 2gdo | 12C | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.444 | |
| 2lzg | 13Q | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.444 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.444 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.444 | |
| 2wtk | ANP | STE20-related kinase adapter protein alpha | / | 0.444 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 2yyy | NAP | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.59 | 0.444 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.444 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.444 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.444 | |
| 3fnl | SHA | Lactoperoxidase | / | 0.444 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.444 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.444 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3mje | NDP | AmphB | / | 0.444 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.444 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.444 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 3tye | XTZ | Dihydropteroate synthase | / | 0.444 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.444 | |
| 3v49 | PK0 | Androgen receptor | / | 0.444 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.444 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.444 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4at9 | UTP | Interleukin enhancer-binding factor 2 | / | 0.444 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.444 | |
| 4cer | VL4 | Integrase | / | 0.444 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.444 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.444 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.443 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.443 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.443 | |
| 1h1p | CMG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.443 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.443 | |
| 1tqp | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.443 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2eud | ANP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.443 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.443 | |
| 2ycf | YCF | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.443 | |
| 3h3c | P1E | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.443 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.443 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.443 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 3qge | 26F | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3rdo | BTN | Streptavidin | / | 0.443 | |
| 3sjh | LAR | Actin, alpha skeletal muscle | / | 0.443 | |
| 3uwb | BB2 | RIIA-RIIB membrane-associated protein | / | 0.443 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.443 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.443 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.443 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4ck2 | NVU | Integrase | / | 0.443 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.443 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.443 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.443 | |
| 4fkj | 11K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.443 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.443 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.443 | |
| 1hnd | COA | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.442 | |
| 1ht5 | FL2 | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.442 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.442 | |
| 1swt | BTN | Streptavidin | / | 0.442 | |
| 1tys | DHF | Thymidylate synthase | / | 0.442 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.442 | |
| 2b56 | UTP | RNA editing complex protein MP57 | / | 0.442 | |
| 2eva | ADN | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.442 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 2hfo | FMN | Activator of photopigment and puc expression | / | 0.442 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.442 | |
| 2izh | BTN | Streptavidin | / | 0.442 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.442 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.442 | |
| 2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.442 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.442 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.442 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3e39 | FMN | Nitroreductase | / | 0.442 | |
| 3eld | SFG | Methyltransferase | / | 0.442 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.442 | |
| 3iaf | TPP | Benzaldehyde lyase | / | 0.442 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3nlb | 5BE | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.442 | |
| 3upt | TPP | Transketolase | / | 0.442 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.442 | |
| 3zpt | M8Y | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4asj | N6A | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 4b4g | KKT | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.442 | |
| 4g3p | UD1 | Bifunctional protein GlmU | / | 0.442 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.442 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.442 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.442 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.442 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.442 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.442 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.442 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.441 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.441 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.441 | |
| 1ja0 | NAP | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.441 | |
| 2ada | HPR | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.441 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.441 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.441 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.441 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.441 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.441 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2z1x | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 3b5i | SAH | Indole-3-acetate O-methyltransferase 1 | / | 0.441 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3elu | SAM | Methyltransferase | / | 0.441 | |
| 3f8k | COA | Uncharacterized protein | / | 0.441 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.441 | |
| 3lcd | BDY | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.441 | |
| 3lfs | A07 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.441 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.441 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.441 | |
| 3tw6 | ADP | Pyruvate carboxylase | / | 0.441 | |
| 4abz | T1C | Tetracycline repressor protein class D | / | 0.441 | |
| 4ajb | TAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.441 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 4cef | D0T | Integrase | / | 0.441 | |
| 4cif | JDX | Integrase | / | 0.441 | |
| 4d7m | TDC | Tetracycline repressor protein class D | / | 0.441 | |
| 4e2b | FMN | Dehydrogenase | / | 0.441 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.441 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.441 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.441 | |
| 4ojb | 198 | Androgen receptor | / | 0.441 | |
| 4pb2 | 5UD | Nucleoside permease | / | 0.441 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.441 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.441 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.441 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 5fko | TDC | Tetracycline repressor protein class D | / | 0.441 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1ats | ADP | Heat shock cognate 71 kDa protein | / | 0.440 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.440 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.440 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.440 | |
| 1nbu | PH2 | Dihydroneopterin aldolase | / | 0.440 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.440 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.440 | |
| 1tdc | UMP | Thymidylate synthase | / | 0.440 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.440 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.440 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.440 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.440 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.440 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.440 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.440 | |
| 2g37 | FAD | Proline dehydrogenase | / | 0.440 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.440 | |
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.440 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.440 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.440 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.440 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.440 | |
| 3w0q | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.440 | |
| 4ag5 | ADP | Type IV secretory pathway VirB4 components-like protein | / | 0.440 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.440 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 4i7f | NVE | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4iaf | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4jlo | ADP | Adenylate kinase | / | 0.440 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.440 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.440 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.440 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.440 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.440 |