sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2qmm | SAM | tRNA (pseudouridine(54)-N(1))-methyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2qmm | SAM | tRNA (pseudouridine(54)-N(1))-methyltransferase | / | 1.000 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.539 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.537 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.521 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.518 | |
| 4lz8 | 1YX | Glutamate receptor 2 | / | 0.515 | |
| 1n2i | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.511 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.511 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.508 | |
| 3a3g | DLZ | Lumazine protein | / | 0.502 | |
| 3s2v | 3HU | Glutamate receptor ionotropic, kainate 1 | / | 0.502 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.501 | |
| 2dxx | SAH | Diphthine synthase | / | 0.501 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.501 | |
| 2pca | SAH | Diphthine synthase | / | 0.500 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.500 | |
| 1wng | SAH | Diphthine synthase | / | 0.499 | |
| 3iob | A4D | Pantothenate synthetase | 6.3.2.1 | 0.499 | |
| 2owg | SAH | Diphthine synthase | / | 0.498 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.498 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.497 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.497 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.496 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.495 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.495 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.494 | |
| 1zp4 | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.494 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.494 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.494 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.493 | |
| 3ivx | FG6 | Pantothenate synthetase | 6.3.2.1 | 0.492 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.492 | |
| 1e82 | M90 | Endothiapepsin | 3.4.23.22 | 0.491 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.491 | |
| 2eld | SAH | Diphthine synthase | / | 0.490 | |
| 2huv | SAH | Diphthine synthase | / | 0.490 | |
| 3tza | TZG | Glutamate receptor 2 | / | 0.490 | |
| 2p5c | SAH | Diphthine synthase | / | 0.489 | |
| 3eld | SFG | Methyltransferase | / | 0.489 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.489 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.488 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.488 | |
| 2hux | SAH | Diphthine synthase | / | 0.487 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.487 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.486 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.486 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.486 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.486 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.485 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.485 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.485 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.485 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.484 | |
| 1n2b | PAF | Pantothenate synthetase | 6.3.2.1 | 0.484 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.484 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.484 | |
| 4z54 | GDP | Neuronal-specific septin-3 | / | 0.484 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.484 | |
| 1dj2 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.483 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 1i6l | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.483 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.483 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.483 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.483 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.483 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.483 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.483 | |
| 4y3q | F02 | Endothiapepsin | 3.4.23.22 | 0.483 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.482 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.482 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.481 | |
| 2p6i | SAH | Diphthine synthase | / | 0.481 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.481 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.480 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.479 | |
| 2p9d | SAH | Diphthine synthase | / | 0.479 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.479 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.478 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.478 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.478 | |
| 1ppk | IVV | Penicillopepsin-1 | 3.4.23.20 | 0.477 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.477 | |
| 2e07 | SAH | Diphthine synthase | / | 0.477 | |
| 2e7r | SAH | Diphthine synthase | / | 0.477 | |
| 2egl | SAH | Diphthine synthase | / | 0.477 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.477 | |
| 3fsu | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.477 | |
| 3s7d | LEU_SER_LYS_LYS_MLZ | N-lysine methyltransferase SMYD2 | / | 0.477 | |
| 4de5 | 0JD | Pantothenate synthetase | 6.3.2.1 | 0.477 | |
| 4dtb | GMP | APH(2'')-Id | / | 0.477 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.476 | |
| 1p1h | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.476 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.476 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.476 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.476 | |
| 2el0 | SAH | Diphthine synthase | / | 0.476 | |
| 2pcg | SAH | Diphthine synthase | / | 0.476 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.476 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.476 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.476 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.476 | |
| 2e4n | SAH | Diphthine synthase | / | 0.475 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.475 | |
| 2pch | SAH | Diphthine synthase | / | 0.475 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.475 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.475 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 3wwm | ADP | [LysW]-aminoadipate kinase | / | 0.475 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.475 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.475 | |
| 4xr9 | NAD | CalS8 | / | 0.475 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.474 | |
| 2bac | FAD | Putative aminooxidase | / | 0.474 | |
| 2v8p | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.474 | |
| 3lm9 | ADP | Putative fructokinase | 2.7.1.4 | 0.474 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.474 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.474 | |
| 4iva | 1J5 | Tyrosine-protein kinase JAK2 | / | 0.474 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.474 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.474 | |
| 4z0g | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.474 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.473 | |
| 2en5 | SAH | Diphthine synthase | / | 0.473 | |
| 2f81 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.473 | |
| 2qs1 | UB1 | Glutamate receptor ionotropic, kainate 1 | / | 0.473 | |
| 2yvf | FAD | Ferredoxin reductase | / | 0.473 | |
| 3coz | 54H | Pantothenate synthetase | 6.3.2.1 | 0.473 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.473 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.473 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.473 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.472 | |
| 2e17 | SAH | Diphthine synthase | / | 0.471 | |
| 2emr | SAH | Diphthine synthase | / | 0.471 | |
| 3a37 | ADP | ATPase GET3 | / | 0.471 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.471 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.471 | |
| 3zhy | FM6 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.471 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.471 | |
| 2e08 | SAH | Diphthine synthase | / | 0.470 | |
| 2gz8 | F3F | Orf1a polyprotein | / | 0.470 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.470 | |
| 2r6g | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.470 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.470 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.470 | |
| 3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.470 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.470 | |
| 4y45 | F91 | Endothiapepsin | 3.4.23.22 | 0.470 | |
| 1a7x | FKA | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.469 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.469 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 3pi5 | 3P5 | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.469 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.468 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.468 | |
| 2x94 | X94 | Angiotensin-converting enzyme | 3.4.15.1 | 0.468 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.467 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.467 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.467 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.467 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.467 | |
| 2dsg | SAH | Diphthine synthase | / | 0.467 | |
| 2okc | SAM | Probable type I restriction enzyme BthVORF4518P M protein | 2.1.1.72 | 0.467 | |
| 2qs4 | LY5 | Glutamate receptor ionotropic, kainate 1 | / | 0.467 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.467 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.467 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.467 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.466 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.466 | |
| 1y56 | ATP | Uncharacterized protein | / | 0.466 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 3cow | 52H | Pantothenate synthetase | 6.3.2.1 | 0.466 | |
| 3rk1 | ATP | N-type ATP pyrophosphatase superfamily | / | 0.466 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.466 | |
| 3w8r | ACP | Uridine kinase | / | 0.466 | |
| 4dt9 | GMP | APH(2'')-Id | / | 0.466 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.465 | |
| 2dsi | SAH | Diphthine synthase | / | 0.465 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.465 | |
| 2e16 | SAH | Diphthine synthase | / | 0.465 | |
| 2fmo | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.465 | |
| 2huq | SAH | Diphthine synthase | / | 0.465 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.465 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.465 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.465 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.464 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.464 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.464 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.464 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.464 | |
| 3tdj | 3TJ | Glutamate receptor 2 | / | 0.464 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.464 | |
| 1b5t | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.463 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.463 | |
| 1f06 | NDP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.463 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.463 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.463 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.463 | |
| 2j08 | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.463 | |
| 2v2v | V12 | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.463 | |
| 3ea0 | ATP | ATPase, ParA family | / | 0.463 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.463 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.463 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.463 | |
| 4xvu | ATP | ATPase GET3 | / | 0.463 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.462 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.462 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 2dxw | SAH | Diphthine synthase | / | 0.462 | |
| 3af4 | GCP | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.462 | |
| 3r9i | ADP | Septum site-determining protein MinD | / | 0.462 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.462 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.462 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.461 | |
| 1zpt | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.461 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.461 | |
| 2e8q | SAH | Diphthine synthase | / | 0.461 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.461 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.461 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 3hr4 | FMN | Nitric oxide synthase, inducible | 1.14.13.39 | 0.461 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.461 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.461 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.461 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.461 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.461 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.461 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.460 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.460 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.460 | |
| 2e8r | SAH | Diphthine synthase | / | 0.460 | |
| 2e8s | SAH | Diphthine synthase | / | 0.460 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.460 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 2p6d | SAH | Diphthine synthase | / | 0.460 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3ing | NDP | Homoserine dehydrogenase related protein | / | 0.460 | |
| 3l7d | DK5 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.460 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.460 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.460 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.460 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.459 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.459 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 2ejz | SAH | Diphthine synthase | / | 0.459 | |
| 2emu | SAH | Diphthine synthase | / | 0.459 | |
| 2ewv | ADP | Twitching motility protein PilT | / | 0.459 | |
| 2pci | SAH | Diphthine synthase | / | 0.459 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.459 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.459 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.459 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.459 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.459 | |
| 3rqq | BA3 | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.459 | |
| 3ts1 | TYA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.459 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.459 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.459 | |
| 4id9 | NAD | Putative UDP-glucose 4-epimerase | / | 0.459 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.459 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.459 | |
| 4kb9 | G79 | Protease | / | 0.459 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 4ypu | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.459 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.459 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.458 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.458 | |
| 1ppl | 1Z7 | Penicillopepsin-1 | 3.4.23.20 | 0.458 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.458 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.458 | |
| 2dxv | SAH | Diphthine synthase | / | 0.458 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.458 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.458 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.458 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3eks | CY9 | Actin-5C | / | 0.458 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.458 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.458 | |
| 3pll | F06 | Endothiapepsin | 3.4.23.22 | 0.458 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.458 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.458 | |
| 5fe1 | 12Q | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.458 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.457 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.457 | |
| 2dek | SAH | Diphthine synthase | / | 0.457 | |
| 2e8h | SAH | Diphthine synthase | / | 0.457 | |
| 2owk | SAH | Diphthine synthase | / | 0.457 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.457 | |
| 2p3b | 3TL | V-1 protease | / | 0.457 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.457 | |
| 2z6r | SAH | Diphthine synthase | / | 0.457 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.457 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.457 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.457 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.457 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.457 | |
| 4z87 | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.457 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.456 | |
| 1i6k | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.456 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.456 | |
| 2egb | SAH | Diphthine synthase | / | 0.456 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 2p5f | SAH | Diphthine synthase | / | 0.456 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.456 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.456 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.456 | |
| 3dv1 | AR9 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3dzv | ADP | Hydroxyethylthiazole kinase | / | 0.456 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.456 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.456 | |
| 3r4b | 74T | Gag-Pol polyprotein | / | 0.456 | |
| 3tog | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.456 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4d9m | 0JO | Diaminopropionate ammonia-lyase | 4.3.1.15 | 0.456 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.456 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.456 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.455 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.455 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 2vhx | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.455 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.455 | |
| 3p8z | 36A | Genome polyprotein | 2.1.1.56 | 0.455 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.455 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.455 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.455 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.454 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.454 | |
| 1sxj | AGS | Replication factor C subunit 1 | / | 0.454 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.454 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.454 | |
| 2pwc | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 2qrq | S13 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.454 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.454 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.454 | |
| 3iaa | TYD | CalG2 | / | 0.454 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3t6i | NC9 | Endothiapepsin | 3.4.23.22 | 0.454 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4a7b | 3W5 | Collagenase 3 | 3.4.24 | 0.454 | |
| 4bup | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.454 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.454 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.453 | |
| 2dph | NAD | Formaldehyde dismutase | / | 0.453 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.453 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.453 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.453 | |
| 2v5u | FMN | Flavodoxin | / | 0.453 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.453 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.453 | |
| 4dxd | 9PC | Cell division protein FtsZ | / | 0.453 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.453 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4ypa | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.453 | |
| 5egh | PC | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 | / | 0.453 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.452 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1i5e | U5P | Uracil phosphoribosyltransferase | / | 0.452 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.452 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.452 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.452 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.452 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.452 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.452 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.452 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.452 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.452 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.452 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.452 | |
| 3a3b | RBF | Lumazine protein | / | 0.452 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.452 | |
| 3fvq | ATP | Fe(3+) ions import ATP-binding protein FbpC | / | 0.452 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.452 | |
| 3h3c | P1E | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.452 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.452 | |
| 4hh4 | SAH | CcbJ | / | 0.452 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.451 | |
| 1hi0 | GTP | RNA-directed RNA polymerase | 2.7.7.48 | 0.451 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.451 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.451 | |
| 2eka | SAH | Diphthine synthase | / | 0.451 | |
| 2ele | SAH | Diphthine synthase | / | 0.451 | |
| 2gg9 | U16 | Methionine aminopeptidase | / | 0.451 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.451 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.451 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.451 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.451 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.451 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.451 | |
| 4hxy | NDP | Plm1 | / | 0.451 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.451 | |
| 4ww0 | ADP | ATP-dependent zinc metalloprotease FtsH | / | 0.451 | |
| 4y38 | 0A9 | Endothiapepsin | 3.4.23.22 | 0.451 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.451 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.450 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.450 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.450 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.450 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 2ccu | 2D9 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.450 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.450 | |
| 2e83 | FMN | FMN-binding protein | / | 0.450 | |
| 2egs | SAH | Diphthine synthase | / | 0.450 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.450 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.450 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.450 | |
| 4k1x | FAD | NADPH:ferredoxin reductase | / | 0.450 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.450 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.449 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.449 | |
| 1qr2 | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.449 | |
| 1upu | U5P | Uracil phosphoribosyltransferase | / | 0.449 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.449 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.449 | |
| 2dsh | SAH | Diphthine synthase | / | 0.449 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.449 | |
| 2g94 | ZPQ | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2g9r | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.449 | |
| 2p6l | SAH | Diphthine synthase | / | 0.449 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.449 | |
| 3t8w | DGZ | M17 leucyl aminopeptidase | / | 0.449 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.449 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.449 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.449 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.448 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.448 | |
| 1gia | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.448 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.448 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.448 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.448 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.448 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.448 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.448 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.448 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.448 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.448 | |
| 2ejj | SAH | Diphthine synthase | / | 0.448 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.448 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2vnj | FAD | NADPH:ferredoxin reductase | / | 0.448 | |
| 2wky | IBC | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.448 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.448 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3koz | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.448 | |
| 3qdl | FMN | Oxygen-insensitive NADPH nitroreductase | / | 0.448 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.448 | |
| 3wbb | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.448 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 4f6r | GDP | Tubulin beta chain | / | 0.448 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.448 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.448 | |
| 4r38 | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.448 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.447 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.447 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.447 | |
| 1z0d | GDP | Ras-related protein Rab-5C | / | 0.447 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.447 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.447 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.447 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.447 | |
| 2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.447 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2zr9 | DTP | Protein RecA | / | 0.447 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.447 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.447 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.447 | |
| 3oii | SAH | Ribosomal RNA small subunit methyltransferase NEP1 | / | 0.447 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.447 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.447 | |
| 4h2d | FMN | NADPH-dependent diflavin oxidoreductase 1 | / | 0.447 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.447 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.447 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.446 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.446 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.446 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.446 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.446 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.446 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.446 | |
| 2e15 | SAH | Diphthine synthase | / | 0.446 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.446 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.446 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.446 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 2yye | APC | Selenide, water dikinase | 2.7.9.3 | 0.446 | |
| 3clt | FAD | Electron transfer flavoprotein subunit alpha | / | 0.446 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.446 | |
| 3ieu | GDP | GTPase Era | / | 0.446 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.446 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.446 | |
| 3prs | RIT | Endothiapepsin | 3.4.23.22 | 0.446 | |
| 3t7p | 7SP | Endothiapepsin | 3.4.23.22 | 0.446 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.446 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.446 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.446 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 1cg1 | IMO | Adenylosuccinate synthetase | / | 0.445 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.445 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1kqb | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.445 | |
| 1vce | SAH | Diphthine synthase | / | 0.445 | |
| 1w5t | ADP | ORC1-type DNA replication protein 2 | / | 0.445 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.445 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.445 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.445 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.445 | |
| 3o7b | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | / | 0.445 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.445 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.445 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.445 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3vob | 9PC | Cell division protein FtsZ | / | 0.445 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.445 | |
| 3zxv | MXI | Glutamine synthetase | 6.3.1.2 | 0.445 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.445 | |
| 4h1v | GNP | Dynamin-1-like protein | 3.6.5.5 | 0.445 | |
| 4j7g | TRH | PCZA361.3 | / | 0.445 | |
| 4kgn | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.445 | |
| 5cyp | GSP | Septin-9 | / | 0.445 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.444 | |
| 1djq | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.444 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.444 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.444 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.444 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2eeq | SAH | Diphthine synthase | / | 0.444 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.444 | |
| 2ha8 | SAH | Probable methyltransferase TARBP1 | / | 0.444 | |
| 2iiq | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.444 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2jji | 0QS | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 2pck | SAH | Diphthine synthase | / | 0.444 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.444 | |
| 2v00 | V15 | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.444 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.444 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.444 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.444 | |
| 3q9l | ATP | Septum site-determining protein MinD | / | 0.444 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3rn8 | RN8 | Glutamate receptor 2 | / | 0.444 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.444 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.444 | |
| 4eo3 | FMN | Bacterioferritin comigratory protein/NADH dehydrogenase | / | 0.444 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.444 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.444 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.444 | |
| 4ynp | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.444 | |
| 5fv0 | ONA | ESX secretion system protein EccC | / | 0.444 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.444 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.444 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.443 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.443 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.443 | |
| 1qf4 | RPD | Adenylosuccinate synthetase | / | 0.443 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.443 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.443 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.443 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.443 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2ogy | C2F | 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase | 2.1.1.258 | 0.443 | |
| 2op9 | WR1 | Orf1ab polyprotein | / | 0.443 | |
| 2owu | SAH | Diphthine synthase | / | 0.443 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.443 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3ms4 | 21N | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.443 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 4ctk | SAM | Genome polyprotein | / | 0.443 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.443 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.443 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.443 | |
| 4h4u | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.443 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.443 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.443 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.443 | |
| 4pgh | SAM | Caffeic acid O-methyltransferase | / | 0.443 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.443 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.443 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.443 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.443 | |
| 1u7h | NAD | Putative ornithine cyclodeaminase | / | 0.442 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 1zp3 | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.442 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.442 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 2hut | SAH | Diphthine synthase | / | 0.442 | |
| 2l8r | APR | O-acetyl-ADP-ribose deacetylase 1 | 3.5.1 | 0.442 | |
| 2qtc | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.442 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 2xyd | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.442 | |
| 2zja | ACP | ATP-dependent DNA helicase Hel308 | / | 0.442 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.442 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.442 | |
| 3ely | SAH | Methyltransferase | / | 0.442 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.442 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.442 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4de1 | 0J6 | Beta-lactamase | / | 0.442 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4i9h | 1E4 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.442 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.442 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.442 | |
| 5b0o | ADP | Flagellum-specific ATP synthase | 3.6.3.14 | 0.442 | |
| 5la6 | GDP | Tubulin beta-2B chain | / | 0.442 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.441 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2iea | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.441 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.441 | |
| 2owv | SAH | Diphthine synthase | / | 0.441 | |
| 2vw5 | BC6 | ATP-dependent molecular chaperone HSP82 | / | 0.441 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.441 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.441 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.441 | |
| 3g2h | KOT | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.441 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.441 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3pb5 | F63 | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.441 | |
| 3t7q | RB4 | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 3zgz | 84T | Leucine--tRNA ligase | / | 0.441 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.441 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.441 | |
| 4gkv | NAD | Alcohol dehydrogenase, propanol-preferring | 1.1.1.1 | 0.441 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 4yvk | SFG | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.441 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.441 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.441 | |
| 1c7o | PPG | Hemolysin | / | 0.440 | |
| 1kh2 | ATP | Argininosuccinate synthase | / | 0.440 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.440 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.440 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1u28 | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.440 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1vso | AT1 | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2bab | FAD | Putative aminooxidase | / | 0.440 | |
| 2el3 | SAH | Diphthine synthase | / | 0.440 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.440 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.440 | |
| 2p2x | SAH | Diphthine synthase | / | 0.440 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.440 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.440 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.440 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 3dm5 | GDP | Signal recognition particle 54 kDa protein | / | 0.440 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.440 | |
| 3e8x | NAP | BH1520 protein | / | 0.440 | |
| 3gon | ANP | Phosphomevalonate kinase | / | 0.440 | |
| 3pm4 | F5N | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.440 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.440 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.440 | |
| 5k5z | ANP | Uncharacterized protein | / | 0.440 |