sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.755 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.729 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.728 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.724 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.715 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.707 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.700 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.653 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.638 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.633 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.621 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.611 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.606 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.603 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.599 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.584 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.578 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.578 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.570 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.564 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.562 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.559 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.559 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.559 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.555 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.555 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.555 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.555 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.552 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.551 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.550 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.550 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.550 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.546 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.546 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.542 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.540 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.540 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.538 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.537 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.537 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.535 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.535 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.534 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.534 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.533 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.532 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.531 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.530 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.529 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.528 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.526 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.525 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.523 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.521 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.518 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.517 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.516 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.514 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.513 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.512 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.511 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.509 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.507 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.502 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.502 | |
| 4iah | 1DX | Alr2278 protein | / | 0.500 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.499 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.497 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.494 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.494 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.494 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.493 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.493 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.493 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.492 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.492 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.490 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.490 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.489 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.489 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.488 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.488 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.488 | |
| 4iae | 1DX | Alr2278 protein | / | 0.488 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.487 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.487 | |
| 3ieu | GDP | GTPase Era | / | 0.487 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.487 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.486 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.486 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.485 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.485 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.485 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.484 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.484 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.483 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.483 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.483 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.482 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.482 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.482 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.482 | |
| 3eks | CY9 | Actin-5C | / | 0.481 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.481 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.480 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.480 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.480 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.480 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.480 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.479 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.479 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.479 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.479 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.479 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.479 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.478 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.478 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.478 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.478 | |
| 3fnl | SHA | Lactoperoxidase | / | 0.478 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.478 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.477 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.477 | |
| 2ohv | NHL | Glutamate racemase | / | 0.477 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.477 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.477 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.477 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.476 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.476 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.476 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.476 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.476 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.475 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.475 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.475 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.475 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.475 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.474 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.474 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.474 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.474 | |
| 4jic | FMN | GTN Reductase | / | 0.474 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.473 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.473 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.473 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.473 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.473 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.473 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.472 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.472 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.472 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.472 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.472 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.472 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.471 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.471 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.471 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.471 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.471 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.471 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.471 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.471 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.470 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.470 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.470 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.470 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.470 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.470 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.470 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.470 | |
| 3r1r | ATP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.470 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.470 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.470 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.470 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.469 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.469 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.469 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.469 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.469 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.469 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.469 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.469 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.469 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.469 | |
| 4r87 | COA | Spermidine N(1)-acetyltransferase | / | 0.469 | |
| 5ftf | ADP | TPR domain protein | / | 0.469 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.469 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.468 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.468 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.468 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.468 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.468 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.468 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.467 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.467 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.467 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.467 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.467 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.467 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.467 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.467 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.467 | |
| 4e2b | FMN | Dehydrogenase | / | 0.467 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.467 | |
| 5bn3 | ADP | NEQ263 | / | 0.467 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.467 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.466 | |
| 1vf3 | GDN | Glutathione S-transferase 3 | 2.5.1.18 | 0.466 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.466 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.466 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.466 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.466 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.466 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.466 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.465 | |
| 1qy8 | RDI | Endoplasmin | / | 0.465 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.465 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.465 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.465 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.465 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.465 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.465 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.464 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.464 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.464 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.464 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.464 | |
| 2i7n | ACO | Pantothenate kinase 1 | 2.7.1.33 | 0.464 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.464 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.464 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.464 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.463 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.463 | |
| 1r2j | FAD | FkbI | / | 0.463 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.463 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.463 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.463 | |
| 2xw1 | 9NV | Serum albumin | / | 0.463 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.463 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.463 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.463 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.463 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.463 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.463 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.463 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.463 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.463 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.463 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.463 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.462 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.462 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.462 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.462 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.462 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.462 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.462 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.462 | |
| 3v2u | ATP | Protein GAL3 | / | 0.462 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.462 | |
| 4p53 | NAI | 2-epi-5-epi-valiolone synthase | / | 0.462 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.462 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.461 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.461 | |
| 1z69 | F42 | 5,10-methylenetetrahydromethanopterin reductase | / | 0.461 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.461 | |
| 4xr9 | NAD | CalS8 | / | 0.461 | |
| 5cyo | GDP | Septin-9 | / | 0.461 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 1i5b | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.460 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.460 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.460 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.460 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.460 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.460 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.460 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.460 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.459 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.459 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.459 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.459 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.459 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.459 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.459 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.459 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.459 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.459 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.459 | |
| 1bmd | NAD | Malate dehydrogenase | / | 0.458 | |
| 1coz | CTP | Glycerol-3-phosphate cytidylyltransferase | 2.7.7.39 | 0.458 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.458 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.458 | |
| 2bxo | OPB | Serum albumin | / | 0.458 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.458 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.458 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.458 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.458 | |
| 4iax | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.458 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.458 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.458 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.458 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.458 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.457 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.457 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 2nli | FMN | Lactate oxidase | / | 0.457 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.457 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.457 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.457 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.457 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.456 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.456 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.456 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.456 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.456 | |
| 3u2m | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.456 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.456 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.455 | |
| 1jq5 | NAD | Glycerol dehydrogenase | 1.1.1.6 | 0.455 | |
| 1n75 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.455 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.455 | |
| 2bxf | DZP | Serum albumin | / | 0.455 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.455 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.455 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.455 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.455 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.455 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.455 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.455 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.455 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 1c7o | PPG | Hemolysin | / | 0.454 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.454 | |
| 1nqw | 5YL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.454 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.454 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.454 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.454 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.454 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.454 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.454 | |
| 2xvq | 9DS | Serum albumin | / | 0.454 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.454 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.454 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.454 | |
| 3wag | TYD | Glycosyltransferase | / | 0.454 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.454 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.454 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.454 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.454 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.453 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.453 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.453 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.453 | |
| 1tez | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.453 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.453 | |
| 2bl4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.453 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.453 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.453 | |
| 2w03 | ADN | AcsD | / | 0.453 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.453 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.453 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
| 3eej | 53R | Uncharacterized protein | / | 0.453 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.453 | |
| 3h3f | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.453 | |
| 3r32 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.453 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.453 | |
| 3vax | PLP | Uncharacterized protein | / | 0.453 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.453 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.453 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.453 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1qy5 | NEC | Endoplasmin | / | 0.452 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.452 | |
| 1xp8 | AGS | Protein RecA | / | 0.452 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.452 | |
| 2yqs | UD1 | UDP-N-acetylglucosamine pyrophosphorylase | 2.7.7.23 | 0.452 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.452 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.452 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.452 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.452 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.452 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.452 | |
| 4n1g | CEI | Obelin | / | 0.452 | |
| 4rje | FNR | Lactate oxidase | / | 0.452 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.452 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.452 | |
| 5dn1 | AMZ | Phosphoribosyl isomerase A | 5.3.1.16 | 0.452 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.451 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 1qr6 | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.451 | |
| 1uhh | CZP | Aequorin-2 | / | 0.451 | |
| 1zio | AP5 | Adenylate kinase | / | 0.451 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.451 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.451 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.451 | |
| 3a3g | DLZ | Lumazine protein | / | 0.451 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.451 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.451 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.451 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.451 | |
| 3tgy | ASC | Lactoperoxidase | 1.11.1.7 | 0.451 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.451 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.451 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.451 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.451 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.451 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.451 | |
| 4v12 | POG | MaoC like domain protein | / | 0.451 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.451 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.450 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.450 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 1yp3 | ATP | Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic | 2.7.7.27 | 0.450 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.450 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.450 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.450 | |
| 2wzw | FMN | Nitroreductase NfnB | / | 0.450 | |
| 3b9l | AZZ | Serum albumin | / | 0.450 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.450 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.450 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.450 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3ogx | H1S | Peptidoglycan recognition protein 1 | / | 0.450 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.450 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.450 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.450 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.450 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.450 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.449 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.449 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.449 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.449 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.449 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.449 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.449 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 2jt2 | C90 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.449 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.449 | |
| 3coz | 54H | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3fpa | DTB | ATP-dependent dethiobiotin synthetase BioD | / | 0.449 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.449 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.449 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.449 | |
| 4gkv | NAD | Alcohol dehydrogenase, propanol-preferring | 1.1.1.1 | 0.449 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.449 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.449 | |
| 4x9m | FAD | Uncharacterized protein MG039 homolog | / | 0.449 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.448 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.448 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.448 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.448 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.448 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.448 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.448 | |
| 2y3r | TRK | TamL | / | 0.448 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.448 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.448 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.448 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.448 | |
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 | 0.448 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.448 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 3w1t | WRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.448 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.448 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.448 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.448 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.448 | |
| 5c41 | ACP | Ribokinase | / | 0.448 | |
| 5dp2 | NAP | CurF | / | 0.448 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.447 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.447 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.447 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.447 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.447 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.447 | |
| 1udc | UFM | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.447 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 2ejz | SAH | Diphthine synthase | / | 0.447 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.447 | |
| 2v8p | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.447 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.447 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.447 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.447 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.447 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 3l5l | FMN | Xenobiotic reductase | / | 0.447 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.447 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.447 | |
| 3vgl | ANP | Glucokinase | / | 0.447 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.447 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.447 | |
| 4kln | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.447 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.447 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.447 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.446 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.446 | |
| 1dj2 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.446 | |
| 1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.446 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.446 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.446 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.446 | |
| 1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.446 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.446 | |
| 2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.446 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.446 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.446 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.446 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.446 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.446 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.446 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.446 | |
| 3qw4 | U5P | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | / | 0.446 | |
| 3u9e | COA | Lmo1369 protein | / | 0.446 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4boe | CLR | Japanin | / | 0.446 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.446 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.446 | |
| 4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.446 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.446 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.446 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.446 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.446 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.446 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.446 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.446 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.445 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.445 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.445 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.445 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.445 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.445 | |
| 2dbz | NAP | Glyoxylate reductase | 1.1.1.26 | 0.445 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.445 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.445 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.445 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.445 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.445 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.445 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.445 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.445 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.445 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3uf6 | COD | Lmo1369 protein | / | 0.445 | |
| 3w2n | ROD | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.445 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.445 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.445 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.445 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.445 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.445 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.445 | |
| 1dgg | NDP | Catalase | 1.11.1.6 | 0.444 | |
| 1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.444 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.444 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.444 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.444 | |
| 2e20 | B4P | Propionate kinase | / | 0.444 | |
| 2fsv | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.444 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.444 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.444 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.444 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.444 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.444 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.444 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.444 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 4die | C5P | Cytidylate kinase | / | 0.444 | |
| 4eet | FMN | Phototropin-2 | 2.7.11.1 | 0.444 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.444 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4k7y | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.444 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.444 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.444 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.444 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.444 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.444 | |
| 5bz4 | COA | Beta-ketothiolase | / | 0.444 | |
| 5cdt | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 5doz | NDP | JamJ | / | 0.444 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.443 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.443 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.443 | |
| 1jf2 | CZH | Obelin | / | 0.443 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.443 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.443 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.443 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.443 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.443 | |
| 2g97 | DGB | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.443 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.443 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.443 | |
| 2y3s | TIR | TamL | / | 0.443 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.443 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.443 | |
| 3c21 | 2BA | DNA integrity scanning protein DisA | / | 0.443 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3clx | X22 | E3 ubiquitin-protein ligase XIAP | 6.3.2 | 0.443 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.443 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.443 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.443 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.443 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.443 | |
| 3w4y | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.443 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.443 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 4dja | FAD | (6-4) photolyase | / | 0.443 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.443 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.443 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.443 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.443 | |
| 4xwt | U5P | Ribonuclease J | / | 0.443 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.443 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.442 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.442 | |
| 1n2b | PAF | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.442 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.442 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.442 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.442 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.442 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 3amf | FMN | FMN-binding protein | / | 0.442 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.442 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.442 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.442 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.442 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.442 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.442 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.442 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.442 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.442 | |
| 4abz | T1C | Tetracycline repressor protein class D | / | 0.442 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.442 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.442 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.442 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.442 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.442 | |
| 4p63 | NAD | Probable deoxyhypusine synthase | 2.5.1.46 | 0.442 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.442 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.442 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.441 | |
| 1r8b | ATP | CCA-adding enzyme | 2.7.7.72 | 0.441 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.441 | |
| 1z44 | FMN | NADPH dehydrogenase | / | 0.441 | |
| 1zdw | FLV | Prenyltransferase | / | 0.441 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.441 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.441 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.441 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.441 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.441 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.441 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.441 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.441 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.441 | |
| 3gf4 | UPG | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.441 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 3t50 | FMN | Blue-light-activated histidine kinase | 2.7.13.3 | 0.441 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.441 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 4cfa | WOP | Integrase | / | 0.441 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.441 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.441 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.441 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.441 | |
| 4fdp | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.441 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4kc2 | WS2 | Histo-blood group ABO system transferase | / | 0.441 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.441 | |
| 4otp | ADP | Serine/threonine-protein kinase RIO1 | 2.7.11.1 | 0.441 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.441 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.441 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1bmf | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.440 | |
| 1bmf | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.440 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.440 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.440 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.440 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.440 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.440 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.440 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.440 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.440 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2e77 | FMN | Lactate oxidase | / | 0.440 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.440 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.440 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.440 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.440 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.440 | |
| 3eld | SFG | Methyltransferase | / | 0.440 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.440 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.440 | |
| 3iob | A4D | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.440 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.440 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.440 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.440 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.440 | |
| 3zuy | TCH | Transporter | / | 0.440 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.440 | |
| 4azw | SAM | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.440 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4e2d | FMN | Dehydrogenase | / | 0.440 | |
| 4e2y | JHZ | Methyltransferase | / | 0.440 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4f9f | GDP | Putative glycosyltransferase | / | 0.440 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.440 | |
| 4h4y | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.440 | |
| 4hms | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.440 | |
| 4l96 | LRG | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.440 |