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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3f8r NAP NADH oxidase/thioredoxin reductase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3f8r NAPNADH oxidase/thioredoxin reductase / 0.878
3f8d FADNADH oxidase/thioredoxin reductase / 0.807
3f8p NADNADH oxidase/thioredoxin reductase / 0.799
2gr1 FADFerredoxin reductase / 0.753
2yvf FADFerredoxin reductase / 0.752
3lzw FADFerredoxin--NADP reductase 2 1.18.1.2 0.751
2q7v FADThioredoxin reductase / 0.749
4nte FADDepH / 0.749
1bxd ANPOsmolarity sensor protein EnvZ 2.7.13.3 0.744
1c4y IH3Prothrombin 3.4.21.5 0.744
1cqs EQUSteroid Delta-isomerase 5.3.3.1 0.744
1crb RTLRetinol-binding protein 1 / 0.744
1cx2 S58Prostaglandin G/H synthase 2 1.14.99.1 0.744
1d3d BZTProthrombin 3.4.21.5 0.744
1dis BDMDihydrofolate reductase 1.5.1.3 0.744
1diu BDMDihydrofolate reductase 1.5.1.3 0.744
1e3k R18Progesterone receptor / 0.744
1e7a PFLSerum albumin / 0.744
1eh4 IC1Casein kinase I homolog 1 2.7.11.1 0.744
1ezv SMACytochrome b / 0.744
1f0q EMOCasein kinase II subunit alpha 2.7.11.1 0.744
1fdu ESTEstradiol 17-beta-dehydrogenase 1 1.1.1.62 0.744
1hnv TBOGag-Pol polyprotein 2.7.7.49 0.744
1hqu HBYGag-Pol polyprotein 2.7.7.49 0.744
1hrv SDZGenome polyprotein / 0.744
1i05 LTLMajor urinary protein 6 / 0.744
1i9m INWCarbonic anhydrase 2 4.2.1.1 0.744
1ikv EFZGag-Pol polyprotein 2.7.7.49 0.744
1iky MSDGag-Pol polyprotein 2.7.7.49 0.744
1jlg UC1Gag-Pol polyprotein 2.7.7.49 0.744
1jlq SBNGag-Pol polyprotein 2.7.7.49 0.744
1jut LYDThymidylate synthase / 0.744
1jx0 DFVChalcone--flavonone isomerase 1 5.5.1.6 0.744
1kb9 SMACytochrome b / 0.744
1kgj FL8Transthyretin / 0.744
1kkq 471Peroxisome proliferator-activated receptor alpha / 0.744
1kqw RTLCellular retinol-binding protein type II / 0.744
1kzu RG1Light-harvesting protein B-800/850 alpha chain / 0.744
1kzu RG1Light-harvesting protein B-800/850 beta chain / 0.744
1m9t INENitric oxide synthase, inducible 1.14.13.39 0.744
1n83 CLRNuclear receptor ROR-alpha / 0.744
1o6q R17Squalene--hopene cyclase 4.2.1.129 0.744
1odc A8BAcetylcholinesterase 3.1.1.7 0.744
1pj6 FOLDimethylglycine oxidase 1.5.3.10 0.744
1q20 PLOSulfotransferase family cytosolic 2B member 1 2.8.2.2 0.744
1qiw DPDCalmodulin / 0.744
1qvt PRLHTH-type transcriptional regulator QacR / 0.744
1rpw DIDHTH-type transcriptional regulator QacR / 0.744
1rt1 MKCGag-Pol polyprotein 2.7.7.49 0.744
1rt2 TNKGag-Pol polyprotein 2.7.7.49 0.744
1rt4 UC1Gag-Pol polyprotein 2.7.7.49 0.744
1rt5 UC2Gag-Pol polyprotein 2.7.7.49 0.744
1s1t UC1Gag-Pol polyprotein 2.7.7.49 0.744
1s1v TNKGag-Pol polyprotein 2.7.7.49 0.744
1s1w UC1Gag-Pol polyprotein 2.7.7.49 0.744
1sej F89Bifunctional dihydrofolate reductase-thymidylate synthase / 0.744
1suo CPZCytochrome P450 2B4 1.14.14.1 0.744
1tkx GWBGag-Pol polyprotein 2.7.7.49 0.744
1tkz H16Gag-Pol polyprotein 2.7.7.49 0.744
1tl3 H20Gag-Pol polyprotein 2.7.7.49 0.744
1tvr TB9Gag-Pol polyprotein 2.7.7.49 0.744
1uyk PUXHeat shock protein HSP 90-alpha / 0.744
1vru AAPGag-Pol polyprotein 2.7.7.49 0.744
1vzd CB3Thymidylate synthase / 0.744
1w4l GL8Acetylcholinesterase 3.1.1.7 0.744
1w76 GNTAcetylcholinesterase 3.1.1.7 0.744
1xk9 P34Exotoxin A 2.4.2.36 0.744
1xws BI1Serine/threonine-protein kinase pim-1 2.7.11.1 0.744
1ysw 43BApoptosis regulator Bcl-2 / 0.744
1z1f STLResveratrol synthase / 0.744
1zg3 2HIIsoflavone 4'-O-methyltransferase / 0.744
1zga HMKIsoflavone 4'-O-methyltransferase / 0.744
1zhy CLROxysterol-binding protein homolog 4 / 0.744
1zhz ERGOxysterol-binding protein homolog 4 / 0.744
1zz1 SHHHistone deacetylase-like amidohydrolase 3.5.1 0.744
2a8g GNGAvidin / 0.744
2acl L05Oxysterols receptor LXR-alpha / 0.744
2agv BHQSarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.744
2aid THKGag-Pol polyprotein 3.4.23.16 0.744
2aot 2PMHistamine N-methyltransferase 2.1.1.8 0.744
2aov C2MHistamine N-methyltransferase 2.1.1.8 0.744
2azy CHDPhospholipase A2, major isoenzyme 3.1.1.4 0.744
2b00 GCHPhospholipase A2, major isoenzyme 3.1.1.4 0.744
2b5j 3ACGag-Pol polyprotein 2.7.7.49 0.744
2ban 357Gag-Pol polyprotein 2.7.7.49 0.744
2bfm TOPPteridine reductase 1 1.5.1.33 0.744
2bil BI1Serine/threonine-protein kinase pim-1 2.7.11.1 0.744
2bjf DXCCholoylglycine hydrolase 3.5.1.24 0.744
2c7x NRBCytochrome P450 monooxygenase PikC / 0.744
2cgf P2NATP-dependent molecular chaperone HSP82 / 0.744
2cib CM6Lanosterol 14-alpha demethylase 1.14.13.70 0.744
2fhj H4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase 2.3.1.101 0.744
2fhk MFNFormylmethanofuran--tetrahydromethanopterin formyltransferase 2.3.1.101 0.744
2fyp RDEEndoplasmin / 0.744
2g44 T3OEstrogen receptor / 0.744
2giu FBREstrogen receptor beta / 0.744
2gm1 2AZKinesin-like protein KIF11 / 0.744
2gyw OBIAcetylcholinesterase 3.1.1.7 0.744
2gz8 F3FOrf1a polyprotein / 0.744
2hnz PC0Gag-Pol polyprotein 2.7.7.49 0.744
2i80 G1LD-alanine--D-alanine ligase / 0.744
2ibz SMACytochrome b / 0.744
2ic3 HBYGag-Pol polyprotein 2.7.7.49 0.744
2j0k 4STFocal adhesion kinase 1 2.7.10.2 0.744
2j2i LY4Serine/threonine-protein kinase pim-1 2.7.11.1 0.744
2kb2 FMNUncharacterized protein / 0.744
2kot ANWProtein S100-A13 / 0.744
2ktd PUCProstaglandin-H2 D-isomerase 5.3.99.2 0.744
2o21 43BApoptosis regulator Bcl-2 / 0.744
2ocf ESTEstrogen receptor / 0.744
2ohv NHLGlutamate racemase / 0.744
2opb F21Phenylethanolamine N-methyltransferase 2.1.1.28 0.744
2pc4 ASP_TRP_ASNFructose-bisphosphate aldolase 4.1.2.13 0.744
2pvh P19Casein kinase II subunit alpha 2.7.11.1 0.744
2q5y TYR_GLY_LEUNuclear pore complex protein Nup98-Nup96 / 0.744
2q6h CXXNa(+):neurotransmitter symporter (Snf family) / 0.744
2q72 IXXNa(+):neurotransmitter symporter (Snf family) / 0.744
2qei CXXNa(+):neurotransmitter symporter (Snf family) / 0.744
2qhw PZZBasic phospholipase A2 VRV-PL-VIIIa 3.1.1.4 0.744
2r9k SGIBeta-galactoside-specific lectin 1 / 0.744
2rbe ZMGCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.744
2std CRPScytalone dehydratase 4.2.1.94 0.744
2uxp CLMHTH-type transcriptional regulator TtgR / 0.744
2vcg S17Histone deacetylase-like amidohydrolase 3.5.1 0.744
2vg5 NNCGag-Pol polyprotein 2.7.7.49 0.744
2vg7 NNIGag-Pol polyprotein 2.7.7.49 0.744
2vq5 LDPS-norcoclaurine synthase / 0.744
2w0b CMWLanosterol 14-alpha demethylase 1.14.13.70 0.744
2w4i VGAGlutamate racemase / 0.744
2w6c BM4Acetylcholinesterase 3.1.1.7 0.744
2xae 2XAKinesin-like protein KIF11 / 0.744
2xby 63CCoagulation factor X 3.4.21.6 0.744
2xiy XIYSerine/threonine-protein kinase pim-1 2.7.11.1 0.744
2xnv VU3Soluble acetylcholine receptor / 0.744
2xuf TZ4Acetylcholinesterase 3.1.1.7 0.744
2xuk TZ5Acetylcholinesterase 3.1.1.7 0.744
2xuo TZ4Acetylcholinesterase 3.1.1.7 0.744
2xw1 9NVSerum albumin / 0.744
2y3s TIRTamL / 0.744
2ycs NXPSerine/threonine-protein kinase Chk2 2.7.11.1 0.744
2yeg XQGHeat shock protein HSP 90-alpha / 0.744
2yne YNEGlycylpeptide N-tetradecanoyltransferase / 0.744
2zdx P4A[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.744
3aba FLICytochrome P450 / 0.744
3aqa BYHBromodomain-containing protein 2 / 0.744
3ar4 TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.744
3arq DM5Chitinase A / 0.744
3ayg HQONitric oxide reductase / 0.744
3bi4 298Polyamine oxidase FMS1 / 0.744
3bpt QUE3-hydroxyisobutyryl-CoA hydrolase, mitochondrial 3.1.2.4 0.744
3br2 DEQHTH-type transcriptional regulator QacR / 0.744
3cgy RDCVirulence sensor histidine kinase PhoQ 2.7.13.3 0.744
3cho 4BGLeukotriene A-4 hydrolase 3.3.2.6 0.744
3clx X22E3 ubiquitin-protein ligase XIAP 6.3.2 0.744
3d27 W29Methionine aminopeptidase / 0.744
3d73 NBBPheromone-binding protein ASP1 / 0.744
3dl9 V2HVitamin D 25-hydroxylase / 0.744
3dnd LL2cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.744
3dy8 IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.744
3dyq IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.744
3exo 5MSBeta-secretase 1 3.4.23.46 0.744
3ey4 352Corticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.744
3f3y 4OABile salt sulfotransferase 2.8.2.14 0.744
3ful 52DLeukotriene A-4 hydrolase 3.3.2.6 0.744
3gcm 5GPPolyribonucleotide nucleotidyltransferase / 0.744
3hxe BD8Geranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.744
3ibd CPZCytochrome P450 2B6 1.14.13 0.744
3il1 B5DGlutamate receptor 2 / 0.744
3inj BXBAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.744
3inl BXBAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.744
3ipt EQUSteroid Delta-isomerase 5.3.3.1 0.744
3itu IBMcGMP-dependent 3',5'-cyclic phosphodiesterase 3.1.4.17 0.744
3iu9 T07Methionine aminopeptidase 2 / 0.744
3iw8 HIZMitogen-activated protein kinase 14 / 0.744
3jx3 JI5Nitric oxide synthase, brain 1.14.13.39 0.744
3keg MREFMN-dependent NADH-azoreductase 1 / 0.744
3kyt HC2Nuclear receptor ROR-gamma / 0.744
3lal KRVGag-Pol polyprotein 2.7.7.49 0.744
3lam KRPGag-Pol polyprotein 2.7.7.49 0.744
3lw0 CCXInsulin-like growth factor 1 receptor 2.7.10.1 0.744
3lzz GDPUncharacterized protein / 0.744
3m6g LO3Actin, alpha skeletal muscle / 0.744
3m8p 65BGag-Pol polyprotein 2.7.7.49 0.744
3mj5 GRMReplicase polyprotein 1a 3.4.22 0.744
3mla JJZProbable nicotinate-nucleotide adenylyltransferase / 0.744
3my5 RFZCyclin-dependent kinase 2 2.7.11.22 0.744
3myu VIBHigh affinity transport system protein p37 / 0.744
3neg PYVAbscisic acid receptor PYL1 / 0.744
3njo P2MAbscisic acid receptor PYR1 / 0.744
3nlj JRRNitric oxide synthase, brain 1.14.13.39 0.744
3nlq JRRNitric oxide synthase, brain 1.14.13.39 0.744
3nly 3XCNitric oxide synthase, brain 1.14.13.39 0.744
3nny 59RNitric oxide synthase, brain 1.14.13.39 0.744
3nzk C90UDP-3-O-acyl-N-acetylglucosamine deacetylase / 0.744
3o73 O73Ribosyldihydronicotinamide dehydrogenase [quinone] / 0.744
3oht 1N1Mitogen-activated protein kinase / 0.744
3owy EQUSteroid Delta-isomerase 5.3.3.1 0.744
3p8h P8HLethal(3)malignant brain tumor-like protein 1 / 0.744
3p99 LNPLanosterol 14-alpha-demethylase / 0.744
3pah XDEPhenylalanine-4-hydroxylase 1.14.16.1 0.744
3pcf FHBProtocatechuate 3,4-dioxygenase beta chain 1.13.11.3 0.744
3pm1 ETHTH-type transcriptional regulator QacR / 0.744
3pmu F7LEndothiapepsin 3.4.23.22 0.744
3psu LJGGag-Pol polyprotein 3.4.23.16 0.744
3pyy 3YYTyrosine-protein kinase ABL1 2.7.10.2 0.744
3q92 XNBKetohexokinase / 0.744
3qgd 26SGenome polyprotein 2.7.7.48 0.744
3qgf 46FGenome polyprotein 2.7.7.48 0.744
3qi4 IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.744
3qm4 PN0Cytochrome P450 2D6 / 0.744
3rox TEPNAD(P)H-hydrate epimerase 5.1.99.6 0.744
3rqj Y2BNitric oxide synthase, brain 1.14.13.39 0.744
3ruk AERSteroid 17-alpha-hydroxylase/17,20 lyase / 0.744
3s1c ZIRCytokinin dehydrogenase 1 1.5.99.12 0.744
3s7b NH5N-lysine methyltransferase SMYD2 / 0.744
3sff 0DIHistone deacetylase 8 3.5.1.98 0.744
3sfh 1DIHistone deacetylase 8 3.5.1.98 0.744
3svp JK5Nitric oxide synthase, brain 1.14.13.39 0.744
3svq JK4Nitric oxide synthase, brain 1.14.13.39 0.744
3szf DCQSulfide-quinone reductase / 0.744
3tk3 CPZCytochrome P450 2B4 1.14.14.1 0.744
3tky N7I(Iso)eugenol O-methyltransferase 2.1.1.146 0.744
3u78 E67Lysine-specific demethylase 7A 1.14.11 0.744
3u9n 09HSerine/threonine-protein kinase Chk1 2.7.11.1 0.744
3ua5 06XCytochrome P450 2B6 1.14.13 0.744
3ufs HW6Nitric oxide synthase, brain 1.14.13.39 0.744
3v1s 0LHStrictosidine synthase 4.3.3.2 0.744
3vgn FNNSteroid Delta-isomerase 5.3.3.1 0.744
3wsb RWZFarnesyltransferase, putative / 0.744
3zr7 OR8Progesterone receptor / 0.744
3zra ORBProgesterone receptor / 0.744
3zrb OR8Progesterone receptor / 0.744
4a5y G7XKinesin-like protein KIF11 / 0.744
4ahv Z5PGag-Pol polyprotein / 0.744
4apu OR8Progesterone receptor / 0.744
4as7 6LXKinesin-like protein KIF11 / 0.744
4awg CI3Polymerase acidic protein / 0.744
4b6u M7GEukaryotic translation initiation factor 4E type 3 / 0.744
4b71 DJLGenome polyprotein 3.4.21.98 0.744
4b76 PW1Genome polyprotein 3.4.21.98 0.744
4b7z Q4QAcetylcholinesterase 3.1.1.7 0.744
4b8u IBK3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase 4.2.1.59 0.744
4bbh YBNGlycylpeptide N-tetradecanoyltransferase / 0.744
4bls APCNTPase P4 / 0.744
4bqg 50QHeat shock protein HSP 90-alpha / 0.744
4chy C5QIntegrase / 0.744
4cx3 HW8Nitric oxide synthase, brain 1.14.13.39 0.744
4dkp 0LLEnvelope glycoprotein gp160 / 0.744
4dku 0KUEnvelope glycoprotein gp160 / 0.744
4dkv 0KWEnvelope glycoprotein gp160 / 0.744
4dlj 6RGMitogen-activated protein kinase 14 / 0.744
4dvq 1CACytochrome P450 11B2, mitochondrial 1.14.15.4 0.744
4dwv PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
4e0u 0MVCyclic dipeptide N-prenyltransferase / 0.744
4e6a 0O9Mitogen-activated protein kinase 14 / 0.744
4e70 N7IConiferyl alcohol 9-O-methyltransferase / 0.744
4ea0 651Dehydrosqualene synthase / 0.744
4eft EFTHeat shock protein HSP 90-alpha / 0.744
4eh3 IRGMitogen-activated protein kinase 14 / 0.744
4eh6 IRGMitogen-activated protein kinase 14 / 0.744
4eh7 0OOMitogen-activated protein kinase 14 / 0.744
4ejv LCLTranscriptional regulator TcaR / 0.744
4erw STUCyclin-dependent kinase 2 2.7.11.22 0.744
4fox D16Thymidylate synthase ThyA / 0.744
4fxy 0W2Neurolysin, mitochondrial 3.4.24.16 0.744
4g09 0VDHistidinol dehydrogenase / 0.744
4guk P2GNeuronal calcium sensor 1 / 0.744
4hmb PZZPhospholipase A2 VRV-PL-VIIIa / 0.744
4hz5 19YDNA topoisomerase 4 subunit B / 0.744
4i1r LZUMucosa-associated lymphoid tissue lymphoma translocation protein 1 3.4.22 0.744
4ig0 1FGGag-Pol polyprotein 2.7.7.49 0.744
4iqq D16Thymidylate synthase / 0.744
4iyg 1HUStrictosidine synthase 4.3.3.2 0.744
4j6d TESCytochrome P450 monooxygenase / 0.744
4j7d I31E3 ubiquitin-protein ligase Mdm2 6.3.2 0.744
4jlj 1NMDeoxycytidine kinase 2.7.1.74 0.744
4jlk 1NODeoxycytidine kinase 2.7.1.74 0.744
4jlt 8PRCytochrome P450 2B4 1.14.14.1 0.744
4jr5 1LSNicotinamide phosphoribosyltransferase 2.4.2.12 0.744
4k3n 1OTM17 leucyl aminopeptidase / 0.744
4kfo 1QSNicotinamide phosphoribosyltransferase 2.4.2.12 0.744
4kqg DMDNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2.4.2.21 0.744
4lg5 A1OAbscisic acid receptor PYL2 / 0.744
4lm4 JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 3.1.4.17 0.744
4lmu QUESerine/threonine-protein kinase pim-1 2.7.11.1 0.744
4m0f 1YKAcetylcholinesterase 3.1.1.7 0.744
4m48 21BSodium-dependent dopamine transporter / 0.744
4man 1Y1Apoptosis regulator Bcl-2 / 0.744
4mfe BTNPyruvate carboxylase / 0.744
4n6h EJ4Delta-type opioid receptor / 0.744
4nbb 9CATerminal oxygenase component of carbazole / 0.744
4nbh 9CATerminal oxygenase component of carbazole / 0.744
4ng5 PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
4nh9 2LCEndoplasmin / 0.744
4o78 SAVBromodomain-containing protein 4 / 0.744
4ple CPSNuclear receptor subfamily 5 group A member 2 / 0.744
4qer STLPhospholipase A2 VRV-PL-VIIIa / 0.744
4qjq OTRLactoperoxidase / 0.744
4r20 AERCytochrome P450 family 17 polypeptide 2 / 0.744
4u95 MIYMultidrug efflux pump subunit AcrB / 0.744
4uym VOR14-alpha sterol demethylase Cyp51B / 0.744
4xoq F42Coenzyme F420:L-glutamate ligase / 0.744
4xp4 COCSodium-dependent dopamine transporter / 0.744
4zp0 DXCMultidrug transporter MdfA / 0.744
5a4w QCTGlutathione S-transferase F2 2.5.1.18 0.744
5c8a 5ADProbable transcriptional regulator / 0.744
5cdg PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
5cds PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
5cuq NSCGenome polyprotein / 0.744
5fli QUEQuercetinase QueD / 0.744
5flj QUEQuercetinase QueD / 0.744
5kj1 PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
5kjc PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
5kje PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
6std MS2Scytalone dehydratase 4.2.1.94 0.744
7std CRPScytalone dehydratase 4.2.1.94 0.744
5xra CLRCannabinoid receptor 1 / 0.744
5l7d CLRSmoothened homolog / 0.744
5dhh DGWNociceptin receptor / 0.744
5dhg DGVNociceptin receptor / 0.744
3pbl ETQD(3) dopamine receptor / 0.744
2eq8 FADDihydrolipoyl dehydrogenase / 0.743
4h4s FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.740
2eq6 FADDihydrolipoyl dehydrogenase / 0.734
3ada NADSubunit alpha of sarocosine oxidase / 0.733
3lzx FADFerredoxin--NADP reductase 2 1.18.1.2 0.732
4jn9 FADDepH / 0.730
2gh5 FADGlutathione reductase, mitochondrial 1.8.1.7 0.727
4h4q FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.724
1ger FADGlutathione reductase 1.8.1.7 0.721
1grb FADGlutathione reductase, mitochondrial 1.8.1.7 0.721
1q1r FADPutidaredoxin reductase 1.18.1.5 0.720
3ab1 FADFerredoxin--NADP reductase 1.18.1.2 0.720
4h50 FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.719
3nlc FADUncharacterized protein / 0.717
2yg6 FADPutrescine oxidase / 0.716
2yg5 FADPutrescine oxidase / 0.715
1cl0 FADThioredoxin reductase 1.8.1.9 0.714
1d4c FADFumarate reductase flavoprotein subunit 1.3.5.4 0.714
2yg3 FADPutrescine oxidase / 0.714
2x8h FADThioredoxin glutathione reductase / 0.713
3rha FDAPutrescine oxidase / 0.713
4ntd FADThioredoxin reductase / 0.713
2yg4 FADPutrescine oxidase / 0.712
4a5l FADThioredoxin reductase / 0.712
2du8 FADD-amino-acid oxidase 1.4.3.3 0.710
3gwf FADCyclohexanone monooxygenase / 0.709
1geu FADGlutathione reductase 1.8.1.7 0.708
1rp0 AHZThiamine thiazole synthase, chloroplastic / 0.708
3ad9 NADSubunit alpha of sarocosine oxidase / 0.708
4la1 FADThioredoxin glutathione reductase / 0.708
5fs6 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.708
1ng3 FADGlycine oxidase 1.4.3.19 0.707
4h4y FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.707
2jb1 FADL-amino acid oxidase / 0.706
3ef6 FADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component 1.18.1.3 0.706
3lb8 FADPutidaredoxin reductase 1.18.1.5 0.706
2jae FADL-amino acid oxidase / 0.705
2gr3 FADFerredoxin reductase / 0.704
2x8g FADThioredoxin glutathione reductase / 0.704
5buk FADFADH2-dependent halogenase / 0.704
2zbw FADFerredoxin--NADP reductase / 0.703
1d4d FADFumarate reductase flavoprotein subunit 1.3.5.4 0.702
3klj FADNADH-rubredoxin oxidoreductase 1.18.1.1 0.702
4up3 FADThioredoxin reductase / 0.702
2v3a FADRubredoxin-NAD(+) reductase 1.18.1.1 0.701
2ym1 FADPhenylacetone monooxygenase 1.14.13.92 0.701
2tmd ADPTrimethylamine dehydrogenase 1.5.8.2 0.700
3t2z FADSulfide-quinone reductase / 0.700
1djn ADPTrimethylamine dehydrogenase 1.5.8.2 0.699
2iid FADL-amino-acid oxidase 1.4.3.2 0.699
2ylr FADPhenylacetone monooxygenase 1.14.13.92 0.699
3r9u FADThioredoxin reductase / 0.699
1dnc FADGlutathione reductase, mitochondrial 1.8.1.7 0.698
1m6i FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.698
3t2k FADSulfide-quinone reductase / 0.698
4jdr FADDihydrolipoyl dehydrogenase 1.8.1.4 0.698
1lqu FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.697
2gvc FADThiol-specific monooxygenase 1.14.13 0.697
3kve FADL-amino-acid oxidase / 0.697
4d04 FADPhenylacetone monooxygenase 1.14.13.92 0.697
4jq9 FADDihydrolipoyl dehydrogenase / 0.697
1gre FADGlutathione reductase, mitochondrial 1.8.1.7 0.696
1grg FADGlutathione reductase, mitochondrial 1.8.1.7 0.696
1tdf FADThioredoxin reductase 1.8.1.9 0.696
4d03 FADPhenylacetone monooxygenase 1.14.13.92 0.696
1grh FADGlutathione reductase, mitochondrial 1.8.1.7 0.695
1gsn FADGlutathione reductase, mitochondrial 1.8.1.7 0.695
2apg FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.695
3djg FADGlutathione reductase, mitochondrial 1.8.1.7 0.695
4hsu FADLysine-specific histone demethylase 1B 1 0.695
1gra FADGlutathione reductase, mitochondrial 1.8.1.7 0.694
3cgb FADCoenzyme A disulfide reductase / 0.694
3uox FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.694
4lii FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.694
4ntc FADThioredoxin reductase gliT / 0.694
1k4q FADGlutathione reductase, mitochondrial 1.8.1.7 0.693
3cgc FADCoenzyme A disulfide reductase / 0.693
3djj FADGlutathione reductase, mitochondrial 1.8.1.7 0.693
4jnq FDAThioredoxin reductase / 0.693
1get FADGlutathione reductase 1.8.1.7 0.692
2eq7 FADDihydrolipoyl dehydrogenase / 0.692
4gus FADLysine-specific histone demethylase 1B 1 0.692
2ard FDAFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.691
2nvk FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.691
3qfa FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.691
4fwf FADLysine-specific histone demethylase 1B 1 0.691
1e1n FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.690
1tde FADThioredoxin reductase 1.8.1.9 0.690
1trb FADThioredoxin reductase 1.8.1.9 0.690
4h4v FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.690
3nta FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.689
3t14 FADSulfide-quinone reductase / 0.689
4gr1 FADGlutathione reductase, mitochondrial 1.8.1.7 0.689
4h4z FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.689
1djq ADPTrimethylamine dehydrogenase 1.5.8.2 0.687
1e1l FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.687
1i8t FADUDP-galactopyranose mutase 5.4.99.9 0.687
1o94 ADPTrimethylamine dehydrogenase 1.5.8.2 0.687
2gr0 FADFerredoxin reductase / 0.687
3dh9 FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.686
4opg FDAConserved Archaeal protein / 0.686
5fs8 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.686
3fbs FADOxidoreductase / 0.685
3sz0 FADSulfide-quinone reductase / 0.685
4cnk FADL-amino acid oxidase / 0.685
4ykg FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.685
1e6e FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.684
3syi FADSulfide-quinone reductase / 0.684
2wow FADTrypanothione reductase / 0.683
2ylw FADPhenylacetone monooxygenase 1.14.13.92 0.683
2ylx FADPhenylacetone monooxygenase 1.14.13.92 0.682
2c7g FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.681
3gd3 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.681
4opi FDAConserved Archaeal protein / 0.681
1cjc FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.680
2bry FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.680
2yls FADPhenylacetone monooxygenase 1.14.13.92 0.680
4opc FDAConserved Archaeal protein / 0.680
4opd FDAConserved Archaeal protein / 0.680
1cf3 FADGlucose oxidase 1.1.3.4 0.679
1e1k FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.679
1e1m FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.679
1jnz FADAdenylylsulfate reductase, subunit A (AprA) / 0.679
2whd FADThioredoxin reductase / 0.679
3k4c FADPyranose 2-oxidase / 0.679
3kpk FADSulfide-quinone reductase / 0.679
1v59 FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.678
1zmd FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.678
3m0o FADMonomeric sarcosine oxidase 1.5.3.1 0.678
3uoy FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.678
1ges FADGlutathione reductase 1.8.1.7 0.677
2jkc FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.677
3pl8 FADPyranose 2-oxidase / 0.677
4gut FADLysine-specific histone demethylase 1B 1 0.677
2qa1 FADPgaE / 0.676
3m12 FADMonomeric sarcosine oxidase 1.5.3.1 0.676
1bwc FADGlutathione reductase, mitochondrial 1.8.1.7 0.675
1gv4 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.675
2cfy FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.675
2gv8 FADThiol-specific monooxygenase 1.14.13 0.675
4j57 FADThioredoxin reductase 2 1.8.1.9 0.675
4yry FADGlutamate synthase, beta subunit / 0.675
1zk7 FADMercuric reductase 1.16.1.1 0.674
1zx9 FADMercuric reductase 1.16.1.1 0.674
4h4r FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.674
4h4t FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.674
1gte FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.673
1h7w FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.673
3cge FADCoenzyme A disulfide reductase / 0.673
3k7m FAD6-hydroxy-L-nicotine oxidase / 0.673
2fjb SFDAdenylylsulfate reductase, subunit A (AprA) / 0.672
4o5u FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.672
3cgd FADCoenzyme A disulfide reductase / 0.671
3dgh FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.671
3oz2 FADDigeranylgeranylglycerophospholipid reductase / 0.671
2i0z FADNAD(FAD)-utilizing dehydrogenases / 0.670
4o5q FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.670
2wba FADTrypanothione reductase 1.8.1.12 0.669
3atq FDAConserved Archaeal protein / 0.669
2ym2 FADPhenylacetone monooxygenase 1.14.13.92 0.668
3k30 ADPHistamine dehydrogenase / 0.668
4bjz FADProbable salicylate monooxygenase / 0.668
2cul FADGidA-related protein / 0.667
3uoz FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.667
3urh FADDihydrolipoyl dehydrogenase / 0.667
4ccq FADThioredoxin reductase / 0.667
4fk1 FADPutative thioredoxin reductase / 0.667
1ng4 FADGlycine oxidase 1.4.3.19 0.666
1w4x FADPhenylacetone monooxygenase 1.14.13.92 0.666
2aqj FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.666
2fje FADAdenylylsulfate reductase, subunit A (AprA) / 0.665
2hqm FADGlutathione reductase 1.8.1.7 0.665
2ar8 FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.664
3t2y FADSulfide-quinone reductase / 0.664
4k2x FADPolyketide oxygenase/hydroxylase / 0.664
1fl2 FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.663
2yg7 FADPutrescine oxidase / 0.663
3lsh FADPyranose 2-oxidase / 0.663
2tpr FADTrypanothione reductase 1.8.1.12 0.662
2ylt FADPhenylacetone monooxygenase 1.14.13.92 0.662
3cnt FADPolyamine oxidase FMS1 / 0.661
4b1b FADThioredoxin reductase 1.8.1.9 0.661
4x9m FADUncharacterized protein MG039 homolog / 0.661
1a8t 061Metallo-beta-lactamase type 2 / 0.660
1acj THAAcetylcholinesterase 3.1.1.7 0.660
1c3x 8IGPurine nucleoside phosphorylase 2.4.2.1 0.660
1d3p BT3Prothrombin 3.4.21.5 0.660
1jt6 DEQHTH-type transcriptional regulator QacR / 0.660
1lqd CMICoagulation factor X 3.4.21.6 0.660
1q0z AKAAclacinomycin methylesterase RdmC 3.1.1.95 0.660
1tvv CB3Thymidylate synthase / 0.660
1yho TRRDihydrofolate reductase 1.5.1.3 0.660
1zzq DP9Nitric oxide synthase, brain 1.14.13.39 0.660
1zzr DP9Nitric oxide synthase, brain 1.14.13.39 0.660
2c6h PXICytochrome P450 monooxygenase PikC / 0.660
2cd8 PXICytochrome P450 monooxygenase PikC / 0.660
2g72 F21Phenylethanolamine N-methyltransferase 2.1.1.28 0.660
2jf0 HBPAcetylcholinesterase 3.1.1.7 0.660
2oae AILDipeptidyl peptidase 4 / 0.660
2pjl 047Steroid hormone receptor ERR1 / 0.660
2pks G44Prothrombin 3.4.21.5 0.660
2qjp ANJCytochrome b / 0.660
2qmz LDPRibosyldihydronicotinamide dehydrogenase [quinone] / 0.660
2v57 PRLTetR family transcriptional regulator / 0.660
2va6 H24Beta-secretase 1 3.4.23.46 0.660
2wd8 VGFPteridine reductase / 0.660
2wog ZZDKinesin-like protein KIF11 / 0.660
3bc4 LLGGag-Pol polyprotein 3.4.23.16 0.660
3bt9 DEQHTH-type transcriptional regulator QacR / 0.660
3btj DEQHTH-type transcriptional regulator QacR / 0.660
3cy2 MB9Serine/threonine-protein kinase pim-1 2.7.11.1 0.660
3dg8 RJ6Bifunctional dihydrofolate reductase-thymidylate synthase 1.5.1.3 0.660
3fu5 492Leukotriene A-4 hydrolase 3.3.2.6 0.660
3fun 798Leukotriene A-4 hydrolase 3.3.2.6 0.660
3gn2 AX8Pteridine reductase / 0.660
3iu8 T03Methionine aminopeptidase 2 / 0.660
3ken ZZDKinesin-like protein KIF11 / 0.660
3kjm 245Cytokinin dehydrogenase 1 1.5.99.12 0.660
3ko0 TFPProtein S100-A4 / 0.660
3pld F90Endothiapepsin 3.4.23.22 0.660
3qai XNNKetohexokinase / 0.660
3t40 3RGIndole-3-glycerol phosphate synthase 4.1.1.48 0.660
3ufv HW9Nitric oxide synthase, brain 1.14.13.39 0.660
3wb4 0B3Beta-secretase 1 3.4.23.46 0.660
3wb5 0B4Beta-secretase 1 3.4.23.46 0.660
4a51 DQ8Kinesin-like protein KIF11 / 0.660
4b12 C23Glycylpeptide N-tetradecanoyltransferase / 0.660
4bbg V02Kinesin-like protein KIF11 / 0.660
4c59 FEFCyclin-G-associated kinase 2.7.11.1 0.660
4c5o FADPutative monooxygenase / 0.660
4cfn JYMCyclin-dependent kinase 2 2.7.11.22 0.660
4cx4 HW9Nitric oxide synthase, brain 1.14.13.39 0.660
4da5 0H7Choline kinase alpha 2.7.1.32 0.660
4eh4 IRGMitogen-activated protein kinase 14 / 0.660
4eip K2CPutative FAD-monooxygenase / 0.660
4enh FVXCholesterol 24-hydroxylase / 0.660
4fog C2FThymidylate synthase ThyA / 0.660
4ha5 13WBeta-secretase 1 3.4.23.46 0.660
4jhz 1KVBeta-glucuronidase 3.2.1.31 0.660
4kfp 1R7Nicotinamide phosphoribosyltransferase 2.4.2.12 0.660
4lm5 Q17Serine/threonine-protein kinase pim-1 2.7.11.1 0.660
4m6p 20RNicotinamide phosphoribosyltransferase 2.4.2.12 0.660
4mm4 8PRNa(+):neurotransmitter symporter (Snf family) / 0.660
4mmd 29ENa(+):neurotransmitter symporter (Snf family) / 0.660
4oal 245Cytokinin dehydrogenase 4 / 0.660
4uco IWHDNA ligase / 0.660
4y3q F02Endothiapepsin 3.4.23.22 0.660
4y3r F06Endothiapepsin 3.4.23.22 0.660
4y4j LNREndothiapepsin 3.4.23.22 0.660
5d7p OCZNAD-dependent protein deacetylase sirtuin-2 3.5.1 0.660
1mo9 FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.659
2igo FADPyranose 2-oxidase / 0.659
2xvi FADPutative flavin-containing monooxygenase / 0.659
3dgz FADThioredoxin reductase 2, mitochondrial 1.8.1.9 0.659
3pvc FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC / 0.659
4mih FADPyranose 2-oxidase 1.1.3.10 0.659
4yjd FADD-amino-acid oxidase 1.4.3.3 0.659
4z43 FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.659
1h81 FADPolyamine oxidase 1.5.3.14 0.658
1y56 ATPUncharacterized protein / 0.658
2wes FADTryptophan 5-halogenase / 0.658
3ute FADUDP-galactopyranose mutase / 0.658
1feb FADTrypanothione reductase 1.8.1.12 0.657
2qa2 FADPolyketide oxygenase CabE / 0.657
3b6d FAECholesterol oxidase 1.1.3.6 0.657
1ju2 FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.656
2yr4 FADPhenylalanine 2-monooxygenase precursor 1.13.12.9 0.656
4dsg FADUncharacterized protein / 0.656
1gth FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.655
1ps9 FAD2,4-dienoyl-CoA reductase 1.3.1.34 0.655
2yqu FADDihydrolipoyl dehydrogenase / 0.654
3int FDAUDP-galactopyranose mutase 5.4.99.9 0.654
3utg FDAUDP-galactopyranose mutase / 0.654
4h4p FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.654
2ylz FADPhenylacetone monooxygenase 1.14.13.92 0.653
3ntd FADFAD-dependent pyridine nucleotide-disulphide oxidoreductase / 0.653
3uth FDAUDP-galactopyranose mutase / 0.653
4aox FADSteroid monooxygenase / 0.653
4j2w FADKynurenine 3-monooxygenase / 0.653
4tlz NAPKtzI / 0.653
4ykf FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.653
5j60 FADThioredoxin reductase / 0.653
2bra FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.652
2wp5 FADTrypanothione reductase / 0.652
3icr FADCoenzyme A disulfide reductase / 0.652
4aos FADSteroid monooxygenase / 0.652
2e1m FADL-glutamate oxidase / 0.651
2r9z FADGlutathione amide reductase / 0.651
3ean FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.651
3ics FADCoenzyme A disulfide reductase / 0.651
3jsk AHZThiamine thiazole synthase / 0.651
4hb9 FADUncharacterized protein / 0.651
5dbj FADFADH2-dependent halogenase PltA / 0.651
4fx9 FADCoenzyme A disulfide reductase 1.8.1.14 0.650