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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1f9aATPNicotinamide-nucleotide adenylyltransferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1f9aATPNicotinamide-nucleotide adenylyltransferase/1.000
1qjfACSIsopenicillin N synthase1.21.3.10.534
4loh1SYStimulator of interferon genes protein/0.532
1qiqACCIsopenicillin N synthase1.21.3.10.511
2qo9ANPEphrin type-A receptor 32.7.10.10.507
2bunFADAppA protein/0.506
4f5dC2EStimulator of interferon genes protein/0.506
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.504
1blzACVIsopenicillin N synthase1.21.3.10.501
4n8iCOAPutative 4-hydroxybutyrate coenzyme A transferase/0.501
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.500
4ffrATPUncharacterized protein/0.499
2zdyADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.497
1g4pFQPThiamine-phosphate synthase/0.496
3vjoANPEpidermal growth factor receptor2.7.10.10.496
4qxp1YEStimulator of interferon genes protein/0.496
1z5cADPType 2 DNA topoisomerase 6 subunit B/0.495
4dieC5PCytidylate kinase/0.495
1i58ADPChemotaxis protein CheA2.7.13.30.494
1mezGDPAdenylosuccinate synthetase isozyme 1/0.493
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.493
2yxuATPPyridoxal kinase2.7.1.350.493
3eblGA4Gibberellin receptor GID1/0.493
3ed1GA3Gibberellin receptor GID1/0.491
4yp12BAStimulator of interferon genes protein/0.491
1i59ADPChemotaxis protein CheA2.7.13.30.490
1hv9UD1Bifunctional protein GlmU/0.489
4hmvWUBPhenazine biosynthesis protein PhzG1.40.489
1jedADPSulfate adenylyltransferase/0.488
1touB1VFatty acid-binding protein, adipocyte/0.488
2jlbUDMUncharacterized protein/0.488
3ad9NADSubunit alpha of sarocosine oxidase/0.488
4jdcNADProbable pyrroline-5-carboxylate dehydrogenase RocA/0.488
4qxr1YEStimulator of interferon genes protein/0.488
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.488
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.488
1m8jNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.487
2iviACWIsopenicillin N synthase1.21.3.10.487
3otwCOAPhosphopantetheine adenylyltransferase/0.487
1u1gBBBUridine phosphorylase2.4.2.30.486
3crlANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.486
3crzFADFerredoxin--NADP+ reductase/0.486
4loi1YCStimulator of interferon genes protein/0.486
3fnlSHALactoperoxidase/0.485
3ntaCOAFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.485
3oev3OEProteasome subunit beta type-53.4.25.10.485
3oev3OEProteasome subunit beta type-63.4.25.10.485
4h6rFDAProline dehydrogenase/0.485
1u71MXADihydrofolate reductase1.5.1.30.484
2y6fM9FIsopenicillin N synthase1.21.3.10.484
3adaNADSubunit alpha of sarocosine oxidase/0.484
4bb3KKAIsopenicillin N synthase1.21.3.10.484
2zsaADPPantothenate kinase2.7.1.330.483
1g4tFTPThiamine-phosphate synthase/0.482
1u1f183Uridine phosphorylase2.4.2.30.482
1xq6NAPUncharacterized protein At5g02240/0.482
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.482
1gjvAGS[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial2.7.11.40.481
1hb1OCVIsopenicillin N synthase1.21.3.10.481
2qo7ANPEphrin type-A receptor 32.7.10.10.481
1hb3SCVIsopenicillin N synthase1.21.3.10.479
1mf0GDPAdenylosuccinate synthetase isozyme 1/0.479
2ituITQEpidermal growth factor receptor2.7.10.10.479
4mv1ADPBiotin carboxylase6.3.4.140.479
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.478
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.478
2qocANPEphrin type-A receptor 32.7.10.10.478
3o153NMThiamine-phosphate synthase/0.478
2rhrEMOPutative ketoacyl reductase1.3.10.477
4jxxATPGlutamine--tRNA ligase6.1.1.180.477
2ft9CHDFatty acid-binding protein 2, liver/0.476
2rd2QSIGlutamine--tRNA ligase6.1.1.180.476
2re8GSUGlutamine--tRNA ligase6.1.1.180.476
3wdsNADNADH-dependent quinuclidinone reductase/0.476
4ead0NPThymidine phosphorylase2.4.2.40.476
1xjqADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.475
1g2vTTPGlucose-1-phosphate thymidylyltransferase/0.474
1vyrFMNPentaerythritol tetranitrate reductase/0.474
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.474
2h2aDNDProbable nicotinate-nucleotide adenylyltransferase/0.474
2qf2GDPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.474
2vbpVB1Isopenicillin N synthase1.21.3.10.474
2vo4GTB2,4-D inducible glutathione S-transferase/0.474
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.474
3uwqU5POrotidine 5'-phosphate decarboxylase/0.474
4fwfFADLysine-specific histone demethylase 1B10.474
4mvcCDCCholine-phosphate cytidylyltransferase A/0.474
1adfTADAlcohol dehydrogenase E chain1.1.1.10.473
1jpaANPEphrin type-B receptor 22.7.10.10.473
2nnqT4BFatty acid-binding protein, adipocyte/0.473
2qw034Z4-chlorobenzoyl CoA ligase/0.473
3mw9NAIGlutamate dehydrogenase 1, mitochondrial1.4.1.30.473
4qms1N1Serine/threonine-protein kinase 242.7.11.10.473
5dstSAHProtein arginine N-methyltransferase 82.1.10.473
5iw5NMNNADH pyrophosphatase/0.473
1euyQSIGlutamine--tRNA ligase6.1.1.180.472
2jlaTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.472
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.472
4du82P0Mevalonate diphosphate decarboxylase/0.472
4mv8ACPBiotin carboxylase6.3.4.140.472
1bk0ACVIsopenicillin N synthase1.21.3.10.471
1f20NAPNitric oxide synthase, brain1.14.13.390.471
1mc5AHEAlcohol dehydrogenase class-31.1.1.10.471
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.471
1ybmNAPUncharacterized protein At5g02240/0.471
2b36NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.471
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.471
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.471
1x8vESLLanosterol 14-alpha demethylase1.14.13.700.470
2w2lNADD-mandelate dehydrogenase/0.470
4jloADPAdenylate kinase/0.470
1xjeGDPVitamin B12-dependent ribonucleotide reductase/0.469
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.469
2a84ATPPantothenate synthetase6.3.2.10.469
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.469
1h6vNDPThioredoxin reductase 1, cytoplasmic1.8.1.90.468
2hayFMNPutative NAD(P)H-flavin oxidoreductase/0.468
2oapANPType II secretion system protein (GspE-2)/0.468
2yx6ADPUncharacterized protein/0.468
3mflDHYProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.468
3mflDHYProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.468
1q19SSCCarbapenam-3-carboxylate synthase6.3.3.60.467
1z2nADPInositol-tetrakisphosphate 1-kinase2.7.1.1340.467
2c3qGTXGlutathione S-transferase theta-12.5.1.180.467
2q46NAPUncharacterized protein At5g02240/0.467
2x0rNADMalate dehydrogenase/0.467
3s79ASDAromatase1.14.14.140.467
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
5cnsCDPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.467
1towCRZFatty acid-binding protein, adipocyte/0.466
2vprTDCTetracycline repressor protein class H/0.466
2zkjADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.466
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.466
3up4NAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.466
4nu0AP5Adenylate kinase/0.466
4nu5NADPhosphonate dehydrogenase1.20.1.10.466
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
5fm7ADPRuvB-like helicase/0.466
1lrkUD1UDP-glucose 4-epimerase5.1.3.20.465
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.465
1suwNAPNAD kinase/0.465
2lbaCHOFatty acid binding protein 6/0.465
2ok7FADFerredoxin--NADP reductase, apicoplast/0.465
2vcmM11Isopenicillin N synthase1.21.3.10.465
3apwDP0Alpha-1-acid glycoprotein 2/0.465
3nl6TPSUncharacterized protein/0.465
4lrjANPUncharacterized protein/0.465
1efvFADElectron transfer flavoprotein subunit alpha, mitochondrial/0.464
1oc1ASVIsopenicillin N synthase1.21.3.10.464
1xjnCDPVitamin B12-dependent ribonucleotide reductase/0.464
2l0xGDPGTP-binding protein Rheb/0.464
2x7hPFNProstaglandin reductase 310.464
3eej53RUncharacterized protein/0.464
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.464
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.464
1g9cBABBotulinum neurotoxin type B3.4.24.690.463
1i59ANPChemotaxis protein CheA2.7.13.30.463
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.463
2q4bNAPUncharacterized protein At5g02240/0.463
2wo7ASVIsopenicillin N synthase1.21.3.10.463
2xh9J01Uncharacterized protein/0.463
3gbuATPUncharacterized sugar kinase PH14592.7.10.463
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.463
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.463
4jc51K5Stimulator of interferon genes protein/0.463
4uz6SCRPalmitoleoyl-protein carboxylesterase NOTUM/0.463
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.462
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.462
3dmhSAMProbable ribosomal RNA small subunit methyltransferase/0.462
3enkUPGUDP-glucose 4-epimerase/0.462
4jxzATPGlutamine--tRNA ligase6.1.1.180.462
4lb2DM5Serum albumin/0.462
5hwsNAP2-dehydropantoate 2-reductase/0.462
1p4aPCPPur operon repressor/0.461
2qujTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.461
2vbdV10Isopenicillin N synthase1.21.3.10.461
2x86ADPADP-L-glycero-D-manno-heptose-6-epimerase/0.461
2xzwATPNitrogen regulatory protein P-II/0.461
3ft8MOJHeat shock protein HSP 90-alpha/0.461
3lfcZ86Mitogen-activated protein kinase 14/0.461
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.461
3zkyWT4Isopenicillin N synthase1.21.3.10.461
4fxy0W2Neurolysin, mitochondrial3.4.24.160.461
4gusFADLysine-specific histone demethylase 1B10.461
4qxq1YEStimulator of interferon genes protein/0.461
4ycoFMNtRNA-dihydrouridine(16) synthase/0.461
1hk1T44Serum albumin/0.460
1kqdFMNOxygen-insensitive NAD(P)H nitroreductase/0.460
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.460
1obnASVIsopenicillin N synthase1.21.3.10.460
1phhFADp-hydroxybenzoate hydroxylase/0.460
1rq1FADEndoplasmic oxidoreductin-11.8.40.460
2fypRDEEndoplasmin/0.460
2qoqANPEphrin type-A receptor 32.7.10.10.460
2qtrNXXProbable nicotinate-nucleotide adenylyltransferase/0.460
2w03ADNAcsD/0.460
2x3jATPAcsD/0.460
3af0GDPPantothenate kinase2.7.1.330.460
3mdmFJZCholesterol 24-hydroxylase/0.460
3pchCHBProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.460
3rgaILDEpoxide hydrolase LasB5.5.10.460
3sptUD1Bifunctional protein GlmU/0.460
4ffmADPUncharacterized protein/0.460
4i02CMPcAMP-activated global transcriptional regulator CRP/0.460
4k9u5AWCytochrome P450 3A4/0.460
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.460
4u0oMTALipoyl synthase 2/0.460
4x8oAP5Adenylate kinase/0.460
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.459
1uzwCDHIsopenicillin N synthase1.21.3.10.459
2bn4NAPNADPH--cytochrome P450 reductase/0.459
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.459
3fr5I4AFatty acid-binding protein, adipocyte/0.459
3gcq1BUMitogen-activated protein kinase 14/0.459
3lu6IMXSerum albumin/0.459
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.459
1i5aACPChemotaxis protein CheA2.7.13.30.458
1j1zATPArgininosuccinate synthase/0.458
1m8gNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.458
1mx0ANPType 2 DNA topoisomerase 6 subunit B/0.458
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.458
3n8nN883-dehydroquinate dehydratase4.2.1.100.458
3qs817DAnthranilate phosphoribosyltransferase/0.458
4en4ATPPyridoxal kinase2.7.1.350.458
4ix5ANPUncharacterized protein/0.458
1ci0FMNPyridoxamine 5'-phosphate oxidase1.4.3.50.457
1l8qADPChromosomal replication initiator protein DnaA/0.457
1snyNAPLD36273p/0.457
2a5kAZPReplicase polyprotein 1ab3.4.220.457
2v3aFADRubredoxin-NAD(+) reductase1.18.1.10.457
3cgcCOACoenzyme A disulfide reductase/0.457
3jzdNADMaleylacetate reductase/0.457
3p62FMNPentaerythritol tetranitrate reductase/0.457
3w8rACPUridine kinase/0.457
4dymIYZActivin receptor type-12.7.11.300.457
4idgNADPutative UDP-glucose 4-epimerase/0.457
4yp5NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.457
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.457
5dt9NADErythronate-4-phosphate dehydrogenase/0.457
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.456
1qm5PLPMaltodextrin phosphorylase2.4.1.10.456
1z5aADPType 2 DNA topoisomerase 6 subunit B/0.456
2cx8SAHRibosomal RNA small subunit methyltransferase E/0.456
2p2fCOAAcetyl-coenzyme A synthetase/0.456
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.456
2tpsTPSThiamine-phosphate synthase/0.456
3fr4F8AFatty acid-binding protein, adipocyte/0.456
3orkAGSSerine/threonine protein kinase/0.456
3zgz84TLeucine--tRNA ligase/0.456
4a862ANMajor pollen allergen Bet v 1-A/0.456
4cf7ADPAdenylate kinase/0.456
4fflADPUncharacterized protein/0.456
4fvqATPTyrosine-protein kinase JAK2/0.456
4tleAGSCircadian clock protein kinase KaiC2.7.11.10.456
1cjvDADAdenylate cyclase type 2/0.455
1cjvDADAdenylate cyclase type 5/0.455
1qruATPGlutamine--tRNA ligase6.1.1.180.455
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.455
1vhnFMNtRNA-dihydrouridine synthase/0.455
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.455
2henADPEphrin type-B receptor 22.7.10.10.455
2wb2FADRE11660p/0.455
3ddnHPVD-3-phosphoglycerate dehydrogenase1.1.1.950.455
3fd6ADPSelenide, water dikinase 12.7.9.30.455
3gcnTYR_GLN_PHESerine endoprotease DegS3.4.21.1070.455
3tnlNADShikimate dehydrogenase (NADP(+))/0.455
4ajj88RL-lactate dehydrogenase A chain1.1.1.270.455
4d04NAPPhenylacetone monooxygenase1.14.13.920.455
4dpy2P0Mevalonate diphosphate decarboxylase/0.455
4e5mNAPPhosphonate dehydrogenase1.20.1.10.455
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.455
1cf2NAPGlyceraldehyde-3-phosphate dehydrogenase/0.454
1i2cUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.454
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.454
1nzfUPGDNA beta-glucosyltransferase/0.454
2g9uG27Glycogen phosphorylase, muscle form2.4.1.10.454
2zbaZBATrichothecene 3-O-acetyltransferase/0.454
3pcg4HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.454
3pcg4HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.454
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.454
4ku2MYA3-oxoacyl-[ACP] synthase III/0.454
4yryNADGlutamate synthase, beta subunit/0.454
5kf9ACOPredicted acetyltransferase/0.454
1cozCTPGlycerol-3-phosphate cytidylyltransferase2.7.7.390.453
1fgxU5PBeta-1,4-galactosyltransferase 1/0.453
1h47C5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.453
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.453
1i5bANPChemotaxis protein CheA2.7.13.30.453
1joaFADNADH peroxidase1.11.1.10.453
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.453
1vbiNADMalate/L-lactate dehydrogenase family protein/0.453
2hchN5AEndoplasmin/0.453
2j5xGSPADP-ribosylation factor 6/0.453
2jb4A14Isopenicillin N synthase1.21.3.10.453
2pakTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.453
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.453
2w6nOA2Biotin carboxylase6.3.4.140.453
2x1eX1EAcyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form2.3.1.1640.453
2zvcSAHPrecorrin-3 C17-methyltransferase/0.453
3kb6NADD-lactate dehydrogenase/0.453
3o15IFPThiamine-phosphate synthase/0.453
4ebfNADPhosphonate dehydrogenase1.20.1.10.453
4g2fC07Ephrin type-A receptor 32.7.10.10.453
4in44IDKelch-like ECH-associated protein 1/0.453
4nmdFDABifunctional protein PutA/0.453
4orkGDPBifunctional AAC/APH2.3.10.453
4own5RGAnthranilate phosphoribosyltransferase/0.453
5kgpACOPredicted acetyltransferase/0.453
1g0rTHMGlucose-1-phosphate thymidylyltransferase/0.452
1lrlUPGUDP-glucose 4-epimerase5.1.3.20.452
1nzdUPGDNA beta-glucosyltransferase/0.452
2eudGCQRibonucleoside-diphosphate reductase large chain 11.17.4.10.452
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.452
2yn8STUEphrin type-B receptor 42.7.10.10.452
3cgdCOACoenzyme A disulfide reductase/0.452
3fhyATPPyridoxal kinase2.7.1.350.452
3ioeA7DPantothenate synthetase6.3.2.10.452
3kb1ADPIron-sulfur cluster carrier protein/0.452
3mx5UTPNucleoprotein/0.452
3nszANPCasein kinase II subunit alpha2.7.11.10.452
3wb2YGPUncharacterized protein MJ0488/0.452
4ji91M3Tyrosine-protein kinase JAK2/0.452
4kgmATPUncharacterized protein/0.452
4wouGDPPhosphoenolpyruvate carboxykinase [GTP]/0.452
1udcUFMUDP-glucose 4-epimerase5.1.3.20.451
1w06W05Isopenicillin N synthase1.21.3.10.451
1xjnDTPVitamin B12-dependent ribonucleotide reductase/0.451
2bu8ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.451
2e0aANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.451
2g8yNADHydroxycarboxylate dehydrogenase B/0.451
2qtvGNPSmall COPII coat GTPase SAR13.6.50.451
2w71L23Biotin carboxylase6.3.4.140.451
3aw9GDUNAD-dependent epimerase/dehydratase/0.451
3nf8CDQGag-Pol polyprotein/0.451
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
4egbNADdTDP-glucose 4,6-dehydratase/0.451
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4gn6TYLLactoperoxidase1.11.1.70.451
4iirANPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.451
4je7BB2Peptide deformylase 1A, chloroplastic/mitochondrial3.5.1.880.451
4jl5ADPAdenylate kinase/0.451
5a65TPPThiamine-triphosphatase3.6.1.280.451
5dozNDPJamJ/0.451
1g9bBABBotulinum neurotoxin type B3.4.24.690.450
1i3nUD1UDP-glucose 4-epimerase/0.450
1i58ACPChemotaxis protein CheA2.7.13.30.450
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.450
2gevCOKPantothenate kinase2.7.1.330.450
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.450
2izrBRKCasein kinase I isoform gamma-32.7.11.10.450
2y6o1N1Ephrin type-A receptor 42.7.10.10.450
2zshGA3Gibberellin receptor GID1A30.450
3cgbCOACoenzyme A disulfide reductase/0.450
3fr28CAFatty acid-binding protein, adipocyte/0.450
3i0aDBHNeutrophil gelatinase-associated lipocalin/0.450
3oibFDAPutative acyl-CoA dehydrogenase/0.450
3q8hAO92-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.450
3sdkP3NProteasome subunit beta type-53.4.25.10.450
3sdkP3NProteasome subunit beta type-63.4.25.10.450
4f9fGDPPutative glycosyltransferase/0.450
4jxrACOAcetyltransferase/0.450
4xgxADPFAD:protein FMN transferase/0.450
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.450
5im3DTPRibonucleoside-diphosphate reductase/0.450
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.449
1cq7PY5Aspartate aminotransferase2.6.1.10.449
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
1eq2ADQADP-L-glycero-D-manno-heptose-6-epimerase/0.449
1yw7A41Methionine aminopeptidase 2/0.449
2dbqNAPGlyoxylate reductase1.1.1.260.449
2pz8APCNH(3)-dependent NAD(+) synthetase/0.449
2wvlGDDMannosyl-3-phosphogylcerate synthase/0.449
2xauADPPre-mRNA-splicing factor ATP-dependent RNA helicase PRP433.6.4.130.449
3dj4UD1Bifunctional protein GlmU/0.449
3w2wATPCRISPR system Cmr subunit Cmr2/0.449
4avlTMPPolymerase acidic protein/0.449
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.449
4iawLIZNeutrophil gelatinase-associated lipocalin/0.449
4k39SAMAnaerobic sulfatase-maturating enzyme1.8.980.449
4kp5E1FCarbonic anhydrase 124.2.1.10.449
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.449
5bt9NAP3-oxoacyl-(Acyl-carrier-protein) reductase/0.449
5eomCTPPutative nucleotidyltransferase MAB21L1/0.449
1hkuNADC-terminal-binding protein 11.1.10.448
1wpgADPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.448
1yrcCAMCamphor 5-monooxygenase1.14.15.10.448
2c29NAPDihydroflavonol 4-reductase/0.448
2hekGDPUncharacterized protein/0.448
2po3T4K4-dehydrase/0.448
2qqfA1RNAD-dependent protein deacetylase HST23.5.10.448
2ylzFADPhenylacetone monooxygenase1.14.13.920.448
3cx8GSPGuanine nucleotide-binding protein subunit alpha-13/0.448
3hpqAP5Adenylate kinase/0.448
3mjrAC2Deoxycytidine kinase2.7.1.740.448
3mx2TTPNucleoprotein/0.448
3ojoPDCCap5O/0.448
4jx1CAHCamphor 5-monooxygenase1.14.15.10.448
4k2rANPTyrosine-protein kinase ZAP-702.7.10.20.448
4k33ACPFibroblast growth factor receptor 32.7.10.10.448
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.448
4ohvANPProtein clpf-1/0.448
4pl3ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.448
4r1lADPPhenylacetate-coenzyme A ligase/0.448
5c8yACPTubulin tyrosine ligase/0.448
1os1ATPPhosphoenolpyruvate carboxykinase (ATP)/0.447
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.447
2dbrNAPGlyoxylate reductase1.1.1.260.447
2j9gADPBiotin carboxylase6.3.4.140.447
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
3d8vUD1Bifunctional protein GlmU/0.447
3epoMP5Phosphomethylpyrimidine synthase/0.447
3f03FMNPentaerythritol tetranitrate reductase/0.447
3rlq3RQHeat shock protein HSP 90-alpha/0.447
3to3ATPPetrobactin biosynthesis protein AsbB/0.447
3tr9PT1Dihydropteroate synthase/0.447
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.447
4c77N01Phenylacetone monooxygenase1.14.13.920.447
4dqwATPInosine-5'-monophosphate dehydrogenase/0.447
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.447
4ivoACJProtoporphyrinogen oxidase1.3.3.40.447
4o4iACPTubulin tyrosine ligase/0.447
4riyANPReceptor tyrosine-protein kinase erbB-32.7.10.10.447
4uyf73BBromodomain-containing protein 2/0.447
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.447
4yswNAIXanthine dehydrogenase/oxidase/0.447
1qrrUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.446
1u3cFADCryptochrome-1/0.446
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
2gjnFMNNitronate monooxygenase1.13.12.160.446
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.446
2ittAEEEpidermal growth factor receptor2.7.10.10.446
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.446
2zsiGA4Gibberellin receptor GID1A30.446
3e8xNAPBH1520 protein/0.446
3hkoANPCalcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands/0.446
3k6l2BBPeptide deformylase3.5.1.880.446
3p3c3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.446
3r9iADPSeptum site-determining protein MinD/0.446
3siiA1RUncharacterized protein/0.446
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
3w233RODihydroorotate dehydrogenase (fumarate)1.3.98.10.446
4f6w0SSCyclin-dependent kinase 82.7.11.220.446
4ipeANPTNF receptor-associated protein 1/0.446
4nm7ADPGlycogen synthase kinase-3 beta2.7.11.260.446
5dw0PLSTryptophan synthase beta chain 14.2.1.200.446
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.446
1bwlFMNNADPH dehydrogenase 11.6.99.10.445
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.445
1g9aBABBotulinum neurotoxin type B3.4.24.690.445
1i44ACPInsulin receptor2.7.10.10.445
1og4NAIT-cell ecto-ADP-ribosyltransferase 2/0.445
1ri2GTGmRNA cap guanine-N7 methyltransferase2.1.1.560.445
1u1cBAUUridine phosphorylase2.4.2.30.445
1yunATPProbable nicotinate-nucleotide adenylyltransferase2.7.7.180.445
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
2cjfRP43-dehydroquinate dehydratase4.2.1.100.445
2eckADPAdenylate kinase/0.445
2ehuNAD1-pyrroline-5-carboxylate dehydrogenase/0.445
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.445
2vkvTDCTetracycline repressor protein class D/0.445
3c35KAIGlutamate receptor ionotropic, kainate 1/0.445
3ddw055Glycogen phosphorylase, liver form2.4.1.10.445
3onwGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.445
3zc3NAPFerredoxin--NADP reductase1.18.1.20.445
4asyN5YGlucose-1-phosphate thymidylyltransferase/0.445
4ig01FGGag-Pol polyprotein2.7.7.490.445
4jyzATPGlutamine--tRNA ligase6.1.1.180.445
4m2bUPGUDP-glucose pyrophosphorylase/0.445
4s32ANPMitogen-activated protein kinase 12.7.11.240.445
5a3bAPRSIR2 family protein/0.445
5iqbGNPBifunctional AAC/APH2.3.10.445
5kf8ACOPredicted acetyltransferase/0.445
1gtrATPGlutamine--tRNA ligase6.1.1.180.444
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.444
1m17AQ4Epidermal growth factor receptor2.7.10.10.444
1mzs6693-oxoacyl-[acyl-carrier-protein] synthase 3/0.444
1o01NADAldehyde dehydrogenase, mitochondrial1.2.1.30.444
1v3sATPSignaling protein/0.444
1ybaNADD-3-phosphoglycerate dehydrogenase1.1.1.950.444
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.444
2bxnIDBSerum albumin/0.444
2iyiFMNAppA, antirepressor of ppsR, sensor of blue light/0.444
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.444
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.444
2v5aLZLBiotin carboxylase6.3.4.140.444
2vd0D27Hematopoietic prostaglandin D synthase/0.444
2vtbFADCryptochrome DASH, chloroplastic/mitochondrial/0.444
2vwu7X1Ephrin type-B receptor 42.7.10.10.444
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.444
3c212BADNA integrity scanning protein DisA/0.444
3dmgSAHProbable ribosomal RNA small subunit methyltransferase/0.444
3frqERYErythromycin resistance repressor protein/0.444
3keuATPPyridoxal kinase2.7.1.350.444
3muoZPRProlyl endopeptidase/0.444
4eji0QACytochrome P450 2A131.14.14.10.444
4qbiAP5Adenylate kinase/0.444
4uyg73BBromodomain-containing protein 2/0.444
4ybnFADFlavin-nucleotide-binding protein/0.444
5c3aURMHisto-blood group ABO system transferase/0.444
5l8lADPAurora kinase A2.7.11.10.444
1jgtAPCCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.443
1lqaNDPProtein tas/0.443
1pkfEPDEpothilone C/D epoxidase1.140.443
1z7eATPBifunctional polymyxin resistance protein ArnA/0.443
2aazCB3Thymidylate synthase2.1.1.450.443
2acxANPG protein-coupled receptor kinase 62.7.11.160.443
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.443
2g8aUMPThymidylate synthase/0.443
2gn8NAPUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.443
2ijgFADCryptochrome DASH, chloroplastic/mitochondrial/0.443
2j2pSC2Ficolin-2/0.443
2nq8ZIDEnoyl-ACP reductase/0.443
2qbuSAHPrecorrin-2 methyltransferase/0.443
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.443
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.443
2y3sTIRTamL/0.443
2z7qACPRibosomal protein S6 kinase alpha-12.7.11.10.443
3gwfFADCyclohexanone monooxygenase/0.443
3kt3TYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.443
3q1kADPD-alanine--D-alanine ligase A6.3.2.40.443
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.443
4bcoT6QCyclin-dependent kinase 22.7.11.220.443
4bfzZVZPantothenate kinase2.7.1.330.443
4ho5DAUGlucose-1-phosphate thymidylyltransferase/0.443
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.443
4ly91YYGlucokinase regulatory protein/0.443
4njoNADD-3-phosphoglycerate dehydrogenase, putative/0.443
4r2mANPUniversal stress protein F/0.443
5cnnANPEpidermal growth factor receptor2.7.10.10.443
5dbyNPSSerum albumin/0.443
5esoISC2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.443
1e7qNAPGDP-L-fucose synthase/0.442
1ej2NADNicotinamide-nucleotide adenylyltransferase2.7.7.10.442
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.442
1kvrNADUDP-glucose 4-epimerase5.1.3.20.442
1np7FADCryptochrome DASH/0.442
1pl6572Sorbitol dehydrogenase1.1.1.140.442
1qvrANPChaperone protein ClpB/0.442
1rm5NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.442
1u4dDBQActivated CDC42 kinase 1/0.442
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.442
2cloPLSTryptophan synthase beta chain4.2.1.200.442
2f3rG5PGuanylate kinase2.7.4.80.442
2ozoANPTyrosine-protein kinase ZAP-702.7.10.20.442
2q9fC3SCholesterol 24-hydroxylase/0.442
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.442
2vcwZZAHematopoietic prostaglandin D synthase/0.442
2w02ATPAcsD/0.442
2ylxFADPhenylacetone monooxygenase1.14.13.920.442
2zsbADPPantothenate kinase2.7.1.330.442
3af1GDPPantothenate kinase2.7.1.330.442
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.442
3q2kNAIProbable oxidoreductase/0.442
3r4oFU3Heat shock protein HSP 90-alpha/0.442
3sxpNADADP-L-glycero-D-mannoheptose-6-epimerase/0.442
3ziaATPATP synthase subunit alpha, mitochondrial/0.442
4a1zADPKinesin-like protein KIF11/0.442
4b2gV1NUncharacterized protein/0.442
4bb432WEphrin type-B receptor 42.7.10.10.442
4bgiNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4ccqNAPThioredoxin reductase/0.442
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.442
4i6gFADCryptochrome-2/0.442
4lb9EVPSerum albumin/0.442
4lh71X8DNA ligase/0.442
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
4ohwATPProtein clpf-1/0.442
4qa0SHHHistone deacetylase 83.5.1.980.442
4uocNCNCinA-like protein/0.442
4yxm2BADNA integrity scanning protein DisA/0.442
5jlaNADPutative short-chain dehydrogenase/reductase/0.442
1culFOKAdenylate cyclase type 2/0.441
1culFOKAdenylate cyclase type 5/0.441
1nhhANPDNA mismatch repair protein MutL/0.441
1qmzATPCyclin-dependent kinase 22.7.11.220.441
1x2hLPALipoate-protein ligase A6.3.1.200.441
1yb5NAPQuinone oxidoreductase1.6.5.50.441
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.441
2bxmIMNSerum albumin/0.441
2dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.441
2exmZIPCyclin-dependent kinase 22.7.11.220.441
2omeNADC-terminal-binding protein 2/0.441
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.441
2ovhAS0Progesterone receptor/0.441
2oxnOANBeta-hexosaminidase/0.441
2p2jPRXAcetyl-coenzyme A synthetase/0.441
2wq7FADRE11660p/0.441
2yegXQGHeat shock protein HSP 90-alpha/0.441
2zpaACOtRNA(Met) cytidine acetyltransferase TmcA/0.441
3blqATPCyclin-dependent kinase 92.7.11.220.441
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3g8dADPBiotin carboxylase6.3.4.140.441
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.441
3r83Z14Cyclin-dependent kinase 22.7.11.220.441
3wygGTPGTP-binding nuclear protein GSP1/CNR1/0.441
4fidGDPG protein alpha subunit, putative/0.441
4ivgANPTNF receptor-associated protein 1/0.441
4jkyADPAdenylate kinase/0.441
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.441
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.441
4xfjANPArgininosuccinate synthase/0.441
4xyeNADFormate dehydrogenase/0.441
5ifyTRHGlucose-1-phosphate thymidylyltransferase/0.441
1bygSTUTyrosine-protein kinase CSK/0.440
1e8hADPVanillyl-alcohol oxidase1.1.3.380.440
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.440
1hk4T44Serum albumin/0.440
1j39UPGDNA beta-glucosyltransferase/0.440
1kqoDNDNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.440
1n2eAPCPantothenate synthetase6.3.2.10.440
1qtqQSIGlutamine--tRNA ligase6.1.1.180.440
1u3dFADCryptochrome-1/0.440
1uxjNADMalate dehydrogenase/0.440
1zrzBI1Protein kinase C iota type2.7.11.130.440
2a1nCAMCamphor 5-monooxygenase1.14.15.10.440
2abbFMNPentaerythritol tetranitrate reductase/0.440
2an9GDPGuanylate kinase2.7.4.80.440
2b8jADNClass B acid phosphatase3.1.3.20.440
2bu2ATP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.440
2eixFADNADH-cytochrome b5 reductase/0.440
2ggqTTPDual sugar-1-phosphate nucleotidylyltransferase/0.440
2hu2NADC-terminal binding protein 1/0.440
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.440
2xpwOTCTetracycline repressor protein class D/0.440
2ylsFADPhenylacetone monooxygenase1.14.13.920.440
2zb3NDPProstaglandin reductase 21.3.1.480.440
3cx6GDPGuanine nucleotide-binding protein subunit alpha-13/0.440
3junAKDPhenazine biosynthesis protein A/B/0.440
3lu8IQXSerum albumin/0.440
3pjtC2EDiguanylate cyclase/phosphodiesterase/0.440
3up5NAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.440
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.440
3x22FMNOxygen-insensitive NAD(P)H nitroreductase/0.440
4bjx73BBromodomain-containing protein 4/0.440
4gxs0YSGlutamate receptor 2/0.440
4hurACOVirginiamycin A acetyltransferase2.3.10.440
4j7xNAPSepiapterin reductase1.1.1.1530.440
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.440