sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5ees | NAP | 4-hydroxy-tetrahydrodipicolinate reductase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5ees | NAP | 4-hydroxy-tetrahydrodipicolinate reductase | / | 1.000 | |
| 1yl7 | NAI | 4-hydroxy-tetrahydrodipicolinate reductase | / | 0.584 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.550 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.517 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.515 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.511 | |
| 3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.510 | |
| 4j7h | TRH | PCZA361.3 | / | 0.510 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.503 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.502 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.498 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.495 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.493 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.492 | |
| 3dwb | RDF | Endothelin-converting enzyme 1 | 3.4.24.71 | 0.491 | |
| 2ejz | SAH | Diphthine synthase | / | 0.489 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.488 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.488 | |
| 3sfx | JAN | Uncharacterized protein | / | 0.488 | |
| 2jgs | BTN | Avidin | / | 0.487 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.487 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.485 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.485 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.485 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.485 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.484 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.483 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.483 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.482 | |
| 3ipk | PMS | Surface protein adhesin | / | 0.482 | |
| 3e4a | QIX | Insulin-degrading enzyme | 3.4.24.56 | 0.481 | |
| 2o3u | NGD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.480 | |
| 3w2f | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.480 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.479 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.478 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.478 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.478 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1nj6 | A5A | Proline--tRNA ligase | / | 0.476 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.476 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.476 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.475 | |
| 3vo8 | GDP | Cell division protein FtsZ | / | 0.475 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.475 | |
| 1lke | DOG | Bilin-binding protein | / | 0.473 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.473 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.473 | |
| 3zhb | NAP | Putative dehydrogenase | / | 0.473 | |
| 1azl | FMN | Flavodoxin | / | 0.472 | |
| 1g9c | BAB | Botulinum neurotoxin type B | 3.4.24.69 | 0.472 | |
| 2l0x | GDP | GTP-binding protein Rheb | / | 0.472 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.472 | |
| 3ele | PLP | Aminotransferase | / | 0.472 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.472 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.472 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.471 | |
| 2x1e | X1E | Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form | 2.3.1.164 | 0.471 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.471 | |
| 3g1o | RF1 | HTH-type transcriptional regulator EthR | / | 0.471 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.471 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.471 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.471 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.470 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.470 | |
| 2vet | UMP | Thymidylate synthase | / | 0.470 | |
| 4ag9 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.470 | |
| 4itm | ATP | Tetraacyldisaccharide 4'-kinase | / | 0.470 | |
| 4loh | 1SY | Stimulator of interferon genes protein | / | 0.470 | |
| 1afs | TES | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.469 | |
| 1lrm | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.469 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.469 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.469 | |
| 1akw | FMN | Flavodoxin | / | 0.468 | |
| 1xqp | 8HG | N-glycosylase/DNA lyase | / | 0.468 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.468 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.468 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.468 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.468 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.467 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.467 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.467 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 2fb3 | 5AD | GTP 3',8-cyclase | 4.1.99.18 | 0.467 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.467 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.467 | |
| 2wgs | 1AZ | Glutamine synthetase | 6.3.1.2 | 0.467 | |
| 3dz4 | C8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.467 | |
| 3g2h | KOT | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.467 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.467 | |
| 5kf9 | COA | Predicted acetyltransferase | / | 0.467 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.466 | |
| 1fls | WAY | Collagenase 3 | 3.4.24 | 0.466 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.466 | |
| 2dsc | APR | ADP-sugar pyrophosphatase | 3.6.1.13 | 0.466 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.466 | |
| 2izf | BTN | Streptavidin | / | 0.466 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.466 | |
| 3co9 | 3MS | Genome polyprotein | 2.7.7.48 | 0.466 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.466 | |
| 3klb | FMN | Uncharacterized protein | / | 0.466 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 4gsu | DWZ | L,D-transpeptidase 2 | 2.3.2 | 0.466 | |
| 4xt8 | TMQ | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.466 | |
| 5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.466 | |
| 2iu8 | UD1 | UDP-3-O-acylglucosamine N-acyltransferase | 2.3.1 | 0.465 | |
| 2qmy | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.465 | |
| 2yig | 5EL | Collagenase 3 | 3.4.24 | 0.465 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.465 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.465 | |
| 4e32 | DWN | Methyltransferase | / | 0.465 | |
| 4iz0 | 2BI | Genome polyprotein | 2.7.7.48 | 0.465 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.465 | |
| 1n4q | LYS_CYS_VAL_ILE_LEU | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.464 | |
| 1rz1 | NAD | Phenol 2-hydroxylase component B | / | 0.464 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.464 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.464 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.464 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.464 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.464 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.464 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.464 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.464 | |
| 4lb9 | EVP | Serum albumin | / | 0.464 | |
| 4yfy | 1YJ | VioF | / | 0.464 | |
| 5cfl | C2E | Stimulator of interferon genes protein | / | 0.464 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.463 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.463 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.463 | |
| 2h2a | DND | Probable nicotinate-nucleotide adenylyltransferase | / | 0.463 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.463 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.463 | |
| 2zwa | SAH | tRNA wybutosine-synthesizing protein 4 | 2.1.1.290 | 0.463 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.463 | |
| 3jq3 | ADP | Lombricine kinase | / | 0.463 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4es5 | MGT | Polymerase basic protein 2 | / | 0.463 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.463 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.462 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.462 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.462 | |
| 2eer | NAD | NAD-dependent alcohol dehydrogenase | 1.1.1.1 | 0.462 | |
| 2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.462 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.462 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.462 | |
| 3rc9 | TLO | Sugar 3-ketoreductase | / | 0.462 | |
| 4jhi | EMU | Nodulin-13 | / | 0.462 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.462 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.461 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.461 | |
| 2a5c | 8DA | Avidin | / | 0.461 | |
| 3l5b | BDO | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.461 | |
| 3q6k | SRO | 43.2 kDa salivary protein | / | 0.461 | |
| 3seq | NXX | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.461 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.461 | |
| 4qbi | AP5 | Adenylate kinase | / | 0.461 | |
| 5ark | UMP | Ribonuclease 4 | 3.1.27 | 0.461 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.460 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.460 | |
| 1w19 | T4P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.460 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.460 | |
| 3exo | 5MS | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.460 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.460 | |
| 4to2 | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.460 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.459 | |
| 1nj5 | P5A | Proline--tRNA ligase | / | 0.459 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.459 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.459 | |
| 4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.459 | |
| 4py0 | 6AT | P2Y purinoceptor 12 | / | 0.459 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.458 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.458 | |
| 3amt | ATP | tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS | 6.3.4.22 | 0.458 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.458 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.458 | |
| 3pn1 | IVH | DNA ligase | / | 0.458 | |
| 3up0 | D7S | aceDAF-12 | / | 0.458 | |
| 4h6p | FMN | Chromate reductase | / | 0.458 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.458 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.458 | |
| 1clq | GDP | DNA-directed DNA polymerase | / | 0.457 | |
| 1j8q | FMN | Flavodoxin | / | 0.457 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1rp4 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.457 | |
| 1t5b | FMN | FMN-dependent NADH-azoreductase | / | 0.457 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2iej | S48 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.457 | |
| 3c1o | NAP | Eugenol synthase | / | 0.457 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.457 | |
| 3pch | CHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.457 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.457 | |
| 4djv | 0KM | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.457 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.457 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.457 | |
| 1a26 | CNA | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.456 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.456 | |
| 1lel | BH7 | Avidin | / | 0.456 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.456 | |
| 1xjq | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.456 | |
| 1zpr | CB3 | Thymidylate synthase | / | 0.456 | |
| 2b4y | APR | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.456 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.456 | |
| 3pcn | DHY | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.456 | |
| 3pcn | DHY | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.456 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 1sir | NBC | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.455 | |
| 2dvm | NAD | 439aa long hypothetical malate oxidoreductase (NAD) [malic enzyme] | / | 0.455 | |
| 2e7r | SAH | Diphthine synthase | / | 0.455 | |
| 2p1p | IAC | Protein TRANSPORT INHIBITOR RESPONSE 1 | / | 0.455 | |
| 2p99 | YE6 | Methionine aminopeptidase | / | 0.455 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.455 | |
| 2wzm | NA7 | Uncharacterized oxidoreductase MSMEG_2407/MSMEI_2346 | / | 0.455 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.455 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.455 | |
| 3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.455 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4yfy | 0FX | VioF | / | 0.455 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.454 | |
| 1szc | CNA | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.454 | |
| 1t57 | FMN | Conserved protein | / | 0.454 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.454 | |
| 1w78 | PD8 | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.454 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.454 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.454 | |
| 3zov | WZV | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4hmw | FMN | Pyridoxamine 5'-phosphate oxidase | / | 0.454 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.454 | |
| 1ddu | DDU | Thymidylate synthase | / | 0.453 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 1swt | BTN | Streptavidin | / | 0.453 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.453 | |
| 1xur | PB5 | Collagenase 3 | 3.4.24 | 0.453 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.453 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.453 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.453 | |
| 3eks | CY9 | Actin-5C | / | 0.453 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.453 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.453 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4kxj | P34 | Nucleoprotein | / | 0.453 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.453 | |
| 1i7c | MGB | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.452 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.452 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 2gz8 | F3F | Orf1a polyprotein | / | 0.452 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.452 | |
| 2izg | BTN | Streptavidin | / | 0.452 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.452 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.452 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.452 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.452 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.452 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.452 | |
| 3ntq | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.452 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.452 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.452 | |
| 4hr2 | ADP | Nucleoside diphosphate kinase | / | 0.452 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.452 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.452 | |
| 5d4u | SAM | Uncharacterized protein MJ0489 | / | 0.452 | |
| 1asc | NPL | Aspartate aminotransferase | 2.6.1.1 | 0.451 | |
| 1g9b | BAB | Botulinum neurotoxin type B | 3.4.24.69 | 0.451 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.451 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 1zos | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.451 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.451 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2mm3 | CHO | Gastrotropin | / | 0.451 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.451 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 3bi4 | 298 | Polyamine oxidase FMS1 | / | 0.451 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.451 | |
| 3dz2 | A8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.451 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3ova | APC | CCA-adding enzyme | 2.7.7.72 | 0.451 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.451 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.451 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 4u7w | NDP | MxaA | / | 0.451 | |
| 1jxz | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.450 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.450 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.450 | |
| 1xi2 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.450 | |
| 1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 0.450 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.450 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.450 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.450 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.450 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.450 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.450 | |
| 3rbq | GLY_ALA_GLY_ALA_DAO | Protein unc-119 homolog A | / | 0.450 | |
| 3vhh | VHH | Avidin | / | 0.450 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.450 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.450 | |
| 4y1b | NAP | AntE | / | 0.450 | |
| 5fkm | TDC | Tetracycline repressor protein class D | / | 0.450 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.449 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.449 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.449 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.449 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.449 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.449 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2emr | SAH | Diphthine synthase | / | 0.449 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.449 | |
| 2rtg | BTN | Streptavidin | / | 0.449 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.449 | |
| 2wtk | ANP | STE20-related kinase adapter protein alpha | / | 0.449 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.449 | |
| 3af4 | GCP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 3c6p | 2S3 | Protein TRANSPORT INHIBITOR RESPONSE 1 | / | 0.449 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3l5d | BDV | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3lzx | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.449 | |
| 3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.449 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3r7n | ASP_VAL_ALA_ACE_ASA | Caspase-2 | 3.4.22.55 | 0.449 | |
| 3ske | 054 | Genome polyprotein | 2.7.7.48 | 0.449 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.449 | |
| 3uph | 0C1 | Genome polyprotein | 2.7.7.48 | 0.449 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.449 | |
| 3zmg | 6Z0 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.449 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.449 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.449 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.449 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.449 | |
| 5c48 | URM | Histo-blood group ABO system transferase | / | 0.449 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.448 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.448 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1muu | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.448 | |
| 1ycf | FMN | Nitric oxide reductase | 1 | 0.448 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.448 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.448 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.448 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.448 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.448 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 3ggc | H26 | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.448 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.448 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.448 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.448 | |
| 1c0a | AMO | Aspartate--tRNA ligase | / | 0.447 | |
| 1g0r | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.447 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.447 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.447 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.447 | |
| 2v8p | CDP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.447 | |
| 2y02 | WHJ | Beta-1 adrenergic receptor | / | 0.447 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.447 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.447 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.447 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.447 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.447 | |
| 4xcz | T3Q | Qdtf | / | 0.447 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.447 | |
| 1fm1 | WAY | Collagenase 3 | 3.4.24 | 0.446 | |
| 1g7u | PEP | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.446 | |
| 1lpc | CMP | Antiviral protein DAP-30 | 3.2.2.22 | 0.446 | |
| 1p4r | 354 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.446 | |
| 1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.446 | |
| 1yc2 | APR | NAD-dependent protein deacylase 2 | / | 0.446 | |
| 2bun | FAD | AppA protein | / | 0.446 | |
| 2cbo | TH2 | Neocarzinostatin | / | 0.446 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.446 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.446 | |
| 2ph8 | 35A | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.446 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.446 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.446 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 3gep | 24H | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.446 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.446 | |
| 3qzy | FAD | FAD-linked sulfhydryl oxidase | / | 0.446 | |
| 3x1d | GDP | Atlastin | 3.6.5 | 0.446 | |
| 3zl8 | ADP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.446 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.446 | |
| 4dya | 0MF | Nucleoprotein | / | 0.446 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 4lwx | MU2 | Ribosome inactivating protein | / | 0.446 | |
| 4utk | FNR | Xenobiotic reductase | / | 0.446 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.446 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 1d8m | BBH | Stromelysin-1 | 3.4.24.17 | 0.445 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.445 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.445 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.445 | |
| 2emu | SAH | Diphthine synthase | / | 0.445 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.445 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.445 | |
| 2nm2 | NEU | Dihydroneopterin aldolase | / | 0.445 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.445 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.445 | |
| 2y3p | SM8 | DNA gyrase subunit A | / | 0.445 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3nzp | PLP | Arginine decarboxylase | / | 0.445 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.445 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.445 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.445 | |
| 4mfe | BTN | Pyruvate carboxylase | / | 0.445 | |
| 4qbh | AP5 | Adenylate kinase | / | 0.445 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.445 | |
| 4y6g | F6F | Tryptophan synthase alpha chain | / | 0.445 | |
| 1avd | BTN | Avidin | / | 0.444 | |
| 1axw | MTX | Thymidylate synthase | / | 0.444 | |
| 1evj | NAD | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.444 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.444 | |
| 1ri4 | SAM | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.444 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.444 | |
| 1wsb | FMN | Flavodoxin | / | 0.444 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.444 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
| 2kce | D16 | Thymidylate synthase | / | 0.444 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2rtm | IMI | Streptavidin | / | 0.444 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.444 | |
| 3g11 | P9C | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.444 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.444 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.444 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 3pdn | SFG | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.444 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.444 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.444 | |
| 4blr | UTP | NTPase P4 | / | 0.444 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4v2g | CTC | Tetracycline repressor protein class D | / | 0.444 | |
| 4x8l | AP5 | Adenylate kinase | / | 0.444 | |
| 1f9a | ATP | Nicotinamide-nucleotide adenylyltransferase | / | 0.443 | |
| 1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.443 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 1wli | FMN | FMN-binding protein | / | 0.443 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.443 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 2wca | NP6 | O-GlcNAcase BT_4395 | / | 0.443 | |
| 3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.443 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.443 | |
| 3e30 | ED4 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.443 | |
| 3kaq | FMN | Flavodoxin | / | 0.443 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3lmh | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 0.443 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.443 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.443 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.443 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.443 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.443 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.443 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4qtn | NNR | Nicotinamide riboside transporter PnuC | / | 0.443 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.442 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.442 | |
| 1ib1 | COT | Serotonin N-acetyltransferase | / | 0.442 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.442 | |
| 1p4a | PCP | Pur operon repressor | / | 0.442 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.442 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.442 | |
| 1xud | PB4 | Collagenase 3 | 3.4.24 | 0.442 | |
| 2bqz | SAH | N-lysine methyltransferase KMT5A | / | 0.442 | |
| 2cul | FAD | GidA-related protein | / | 0.442 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.442 | |
| 2h63 | NAP | Biliverdin reductase A | 1.3.1.24 | 0.442 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.442 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.442 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.442 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.442 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.442 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.442 | |
| 3jq6 | DX1 | Pteridine reductase, putative | / | 0.442 | |
| 3koz | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.442 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.442 | |
| 3rl4 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.442 | |
| 3swc | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.442 | |
| 3tlc | 7MD | Microcin C7 self-immunity protein MccF | / | 0.442 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.442 | |
| 4gi5 | FAD | Putative NAD(P)H dehydrogenase (Quinone) | / | 0.442 | |
| 4j7g | TRH | PCZA361.3 | / | 0.442 | |
| 4uyg | 73B | Bromodomain-containing protein 2 | / | 0.442 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.442 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.442 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.442 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.442 | |
| 5egh | PC | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 | / | 0.442 | |
| 5d5b | CAU | Beta-2 adrenergic receptor | / | 0.442 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.442 | |
| 1ank | ANP | Adenylate kinase | / | 0.441 | |
| 1kf6 | HQO | Fumarate reductase iron-sulfur subunit | 1.3.5.1 | 0.441 | |
| 1kf6 | HQO | Fumarate reductase subunit C | / | 0.441 | |
| 1kf6 | HQO | Fumarate reductase subunit D | / | 0.441 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.441 | |
| 1qji | PKF | Astacin | / | 0.441 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.441 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.441 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.441 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.441 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.441 | |
| 2g94 | ZPQ | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.441 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2p4s | DIH | AGAP005945-PA | / | 0.441 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.441 | |
| 2v34 | CTN | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.441 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 2y0d | UGA | UDP-glucose dehydrogenase | / | 0.441 | |
| 2y1w | 849 | Histone-arginine methyltransferase CARM1 | / | 0.441 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.441 | |
| 3cw9 | 01A | 4-chlorobenzoyl CoA ligase | / | 0.441 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.441 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.441 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.441 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 3rhd | NAP | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.441 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.441 | |
| 4cth | RDF | Neprilysin | / | 0.441 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 0.441 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.441 | |
| 4h2d | FMN | NADPH-dependent diflavin oxidoreductase 1 | / | 0.441 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.441 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.441 | |
| 4qfx | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.441 | |
| 4wlj | IK2 | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.441 | |
| 4y0k | NAP | AntE | / | 0.441 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.441 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.440 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.440 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.440 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.440 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.440 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2d2g | DZZ | Phosphotriesterase | / | 0.440 | |
| 2fvc | 888 | Polyprotein | / | 0.440 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.440 | |
| 2pid | YSA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.440 | |
| 2qe2 | 452 | Polyprotein | / | 0.440 | |
| 2xeg | CI9 | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.440 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.440 | |
| 3eku | CY9 | Actin-5C | / | 0.440 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.440 | |
| 3h2c | B58 | Dihydropteroate synthase | / | 0.440 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.440 | |
| 3m53 | SAH | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 0.440 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.440 | |
| 4dxl | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 4fgj | 1PQ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.440 | |
| 4qak | 2AM | RNA 2',3'-cyclic phosphodiesterase | / | 0.440 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.440 |