sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	S-adenosylmethionine decarboxylase proenzyme
ID:	DCAM_HUMAN
AC:	P17707
Organism:	Homo sapiens
Reign:	Eukaryota
TaxID:	9606
EC Number:	4.1.1.50

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Chains:

Chain Name:	Percentage of Residues within binding site
B	36 %
A	64 %

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Ligand binding site composition:

B-Factor:	21.793
Number of residues:	27
Including
Standard Amino Acids:	27
Non Standard Amino Acids:	0
Water Molecules:	0
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
0.675	398.250

% Hydrophobic	% Polar
47.46	52.54
According to VolSite

HET Code:	C8M
Formula:	C15H24N7O4
Molecular weight:	366.396 g/mol
DrugBank ID:	-
Buried Surface Area:	69.64 %
Polar Surface area:	166.84 Å2

Number of
H-Bond Acceptors:	8
H-Bond Donors:	5
Rings:	3
Aromatic rings:	2
Anionic atoms:	0
Cationic atoms:	1
Rule of Five Violation:	1
Rotatable Bonds:	6

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Mass center Coordinates

X	Y	Z
-27.1364	-3.92946	38.8543

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