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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3dz4 C8M S-adenosylmethionine decarboxylase proenzyme 4.1.1.50

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
3dz4 C8MS-adenosylmethionine decarboxylase proenzyme 4.1.1.50 0.919
3dz2 A8MS-adenosylmethionine decarboxylase proenzyme 4.1.1.50 0.818
3h0v M2TS-adenosylmethionine decarboxylase proenzyme 4.1.1.50 0.803
3dz7 O8MS-adenosylmethionine decarboxylase proenzyme 4.1.1.50 0.802
3h0w N8MS-adenosylmethionine decarboxylase proenzyme 4.1.1.50 0.801
3dz6 M8ES-adenosylmethionine decarboxylase proenzyme 4.1.1.50 0.787
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744