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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4aoi4K0Hepatocyte growth factor receptor2.7.10.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4aoi4K0Hepatocyte growth factor receptor2.7.10.11.000
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.746
3zxzKRWHepatocyte growth factor receptor2.7.10.10.688
4gg70J8Hepatocyte growth factor receptor2.7.10.10.676
3zze6XPHepatocyte growth factor receptor2.7.10.10.638
4gg50J3Hepatocyte growth factor receptor2.7.10.10.637
2wgjVGHHepatocyte growth factor receptor2.7.10.10.636
4deg0JJHepatocyte growth factor receptor2.7.10.10.628
4ap7F47Hepatocyte growth factor receptor2.7.10.10.616
2wkmPFYHepatocyte growth factor receptor2.7.10.10.588
3zbx6XEHepatocyte growth factor receptor2.7.10.10.584
3a4pDFQHepatocyte growth factor receptor2.7.10.10.579
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.532
3tucFPWTyrosine-protein kinase SYK2.7.10.20.529
2xikJ60Serine/threonine-protein kinase 252.7.11.10.528
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.522
4kb81QOCasein kinase I isoform delta2.7.11.10.522
3mtlFEFCyclin-dependent kinase 162.7.11.220.521
2i0v6C3Macrophage colony-stimulating factor 1 receptor2.7.10.10.520
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.520
3iw4LW4Protein kinase C alpha type2.7.11.130.520
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.519
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.519
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.517
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.517
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.516
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.516
3zh8C58Protein kinase C iota type2.7.11.130.516
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.515
2qo9ANPEphrin type-A receptor 32.7.10.10.514
3c1xCKKHepatocyte growth factor receptor2.7.10.10.513
1oi9N20Cyclin-dependent kinase 22.7.11.220.512
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
2j0m4STFocal adhesion kinase 12.7.10.20.510
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.510
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.509
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.507
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.506
4gmy0X5Tyrosine-protein kinase JAK2/0.505
4qmpDKISerine/threonine-protein kinase 242.7.11.10.505
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.505
1rw8580TGF-beta receptor type-12.7.11.300.503
2vmyFFOSerine hydroxymethyltransferase/0.503
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.503
1ppjANYCytochrome b/0.502
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.502
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.502
5e8wSTUTGF-beta receptor type-12.7.11.300.502
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.501
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.501
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.501
3rk507ZCyclin-dependent kinase 22.7.11.220.501
4qnaX11Serine/threonine-protein kinase 242.7.11.10.501
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.500
1oiyN41Cyclin-dependent kinase 22.7.11.220.499
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.499
3tnwF18Cyclin-dependent kinase 22.7.11.220.499
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.497
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.497
1e9hINRCyclin-dependent kinase 22.7.11.220.496
2ittAEEEpidermal growth factor receptor2.7.10.10.496
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.496
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.496
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.495
3c4zADPRhodopsin kinase/0.495
4qmzB49Serine/threonine-protein kinase 242.7.11.10.495
4uyg73BBromodomain-containing protein 2/0.495
1kl2FONSerine hydroxymethyltransferase/0.494
2qboCAMCamphor 5-monooxygenase1.14.15.10.494
2uzlC94Cyclin-dependent kinase 22.7.11.220.494
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.493
2j4z626Aurora kinase A2.7.11.10.493
3t8oATPRhodopsin kinase/0.493
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.493
4bchT7ZCyclin-dependent kinase 92.7.11.220.493
4fnyI3KALK tyrosine kinase receptor2.7.10.10.493
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.492
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.492
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.492
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.492
4c02TAKActivin receptor type-12.7.11.300.492
4iwd1JCHepatocyte growth factor receptor2.7.10.10.492
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.492
1u4dDBQActivated CDC42 kinase 1/0.491
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.491
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.491
3ddpRC8Cyclin-dependent kinase 22.7.11.220.491
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.490
2x1nX1NCyclin-dependent kinase 22.7.11.220.490
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.490
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.490
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.490
1pjkANPCasein kinase II subunit alpha2.7.11.10.489
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.489
1r2jFADFkbI/0.488
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.488
3ddw055Glycogen phosphorylase, liver form2.4.1.10.488
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.488
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.487
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.487
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.487
3bhtMFRCyclin-dependent kinase 22.7.11.220.487
3fz1B98Cyclin-dependent kinase 22.7.11.220.487
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.487
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.487
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.486
2wxvWXVCyclin-dependent kinase 22.7.11.220.486
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.486
4qo9627Serine/threonine-protein kinase 242.7.11.10.486
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.485
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.485
4fkr45KCyclin-dependent kinase 22.7.11.220.485
4hy6FJ1Heat shock protein HSP 90-alpha/0.485
1h1s4SPCyclin-dependent kinase 22.7.11.220.484
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.484
1unlRRCCyclin-dependent-like kinase 52.7.11.10.483
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.483
2bkzSBCCyclin-dependent kinase 22.7.11.220.482
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.482
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.482
2wotZZGTGF-beta receptor type-12.7.11.300.482
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.482
3c50ADPRhodopsin kinase/0.482
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.482
4eomATPCyclin-dependent kinase 22.7.11.220.482
4k8aK8AFocal adhesion kinase 12.7.10.20.482
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.481
2wipP49Cyclin-dependent kinase 22.7.11.220.481
3nmpPYVAbscisic acid receptor PYL2/0.481
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.481
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.481
4bis8HQLysine-specific demethylase 4A1.14.110.481
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.481
5bt52LOBromodomain-containing protein 2/0.481
2cchATPCyclin-dependent kinase 22.7.11.220.480
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.480
3ibqATPPyridoxal kinase/0.480
3qzhX69Cyclin-dependent kinase 22.7.11.220.480
4fod0UVALK tyrosine kinase receptor2.7.10.10.480
1di8DTQCyclin-dependent kinase 22.7.11.220.479
1t85CAMCamphor 5-monooxygenase1.14.15.10.479
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.479
3r73X87Cyclin-dependent kinase 22.7.11.220.479
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.479
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.479
2hog710Serine/threonine-protein kinase Chk12.7.11.10.478
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.478
2iw84SPCyclin-dependent kinase 22.7.11.220.478
2vcmM11Isopenicillin N synthase1.21.3.10.478
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.478
3slkNDPPolyketide synthase extender module 2/0.478
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.478
4i22IREEpidermal growth factor receptor2.7.10.10.478
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.478
1uy8PU5Heat shock protein HSP 90-alpha/0.477
2p5uNADUDP-glucose 4-epimerase/0.477
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.477
3uleC69Actin-related protein 3/0.477
4bcpT3CCyclin-dependent kinase 22.7.11.220.477
4lopSB4Mitogen-activated protein kinase 14/0.477
2eufLQQCyclin-dependent kinase 62.7.11.220.476
2i40BLZCyclin-dependent kinase 22.7.11.220.476
3biz61EWee1-like protein kinase2.7.10.20.476
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.476
3i60E86Mitogen-activated protein kinase 12.7.11.240.476
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.475
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.475
3tn8F18Cyclin-dependent kinase 92.7.11.220.475
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.475
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.475
1v59FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.474
2h94FADLysine-specific histone demethylase 1A10.474
3r9oZ71Cyclin-dependent kinase 22.7.11.220.474
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.474
4foc0UUALK tyrosine kinase receptor2.7.10.10.474
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.474
1x8lOXRRetinol dehydratase/0.473
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.473
2vagV25Dual specificity protein kinase CLK12.7.12.10.473
3a60STURibosomal protein S6 kinase beta-12.7.11.10.473
3c4xATPRhodopsin kinase/0.473
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.473
4l9q9TPSerum albumin/0.473
1uy9PU6Heat shock protein HSP 90-alpha/0.472
2j0j4STFocal adhesion kinase 12.7.10.20.472
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.472
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.472
3efwAK8Aurora kinase A2.7.11.10.472
3uli1N3Cyclin-dependent kinase 22.7.11.220.472
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.472
4egnTWOCytochrome P450/0.472
4eoi1ROCyclin-dependent kinase 22.7.11.220.472
4eol1ROCyclin-dependent kinase 22.7.11.220.472
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.472
2jedLG8Protein kinase C theta type2.7.11.130.471
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.471
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.471
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.471
4erwSTUCyclin-dependent kinase 22.7.11.220.471
4ewhT77Activated CDC42 kinase 1/0.471
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.471
4looSB4Mitogen-activated protein kinase 14/0.471
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
1fvv107Cyclin-dependent kinase 22.7.11.220.470
1hk5T44Serum albumin/0.470
1lwlDSOCamphor 5-monooxygenase1.14.15.10.470
1oiuN76Cyclin-dependent kinase 22.7.11.220.470
2dwpACP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.470
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.470
2yeiXQIHeat shock protein HSP 90-alpha/0.470
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.470
4yuqKS1Calmodulin-like domain protein kinase/0.470
5aabVGHALK tyrosine kinase receptor2.7.10.10.470
1dajMOTDihydrofolate reductase1.5.1.30.469
1dz8CAMCamphor 5-monooxygenase1.14.15.10.469
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.469
2acxANPG protein-coupled receptor kinase 62.7.11.160.469
2v7a627Tyrosine-protein kinase ABL12.7.10.20.469
3uyt0CKCasein kinase I isoform delta2.7.11.10.469
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.469
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.469
4ocvANPAminoglycoside phosphotransferase/0.469
5auuLU2Death-associated protein kinase 12.7.11.10.469
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.468
2qbmCAMCamphor 5-monooxygenase1.14.15.10.468
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.468
3ral04ZCyclin-dependent kinase 22.7.11.220.468
1pkdUCNCyclin-dependent kinase 22.7.11.220.467
2itnANPEpidermal growth factor receptor2.7.10.10.467
2wihP48Cyclin-dependent kinase 22.7.11.220.467
2ykjYKJHeat shock protein HSP 90-alpha/0.467
3lxiCAMCytochrome P450/0.467
3sa27DRDihydrofolate reductase/0.467
4c66H4CBromodomain-containing protein 4/0.467
4hni16WCasein kinase I isoform epsilon2.7.11.10.467
4l9i8PRRhodopsin kinase/0.467
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.467
5aacVGHALK tyrosine kinase receptor2.7.10.10.467
1ae8AZLProthrombin3.4.21.50.466
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.466
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.466
2i1vADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.466
2xnbY8LCyclin-dependent kinase 22.7.11.220.466
3bqr4RBDeath-associated protein kinase 3/0.466
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.466
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.466
3ih0ANPUncharacterized sugar kinase PH14592.7.10.466
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.466
3roy22ZCyclin-dependent kinase 22.7.11.220.466
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.466
4fx360KCyclin-dependent kinase 22.7.11.220.466
4g2fC07Ephrin type-A receptor 32.7.10.10.466
4hgs15GCasein kinase I isoform gamma-32.7.11.10.466
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.466
4utdACPAurora kinase A2.7.11.10.466
2izt23DCasein kinase I isoform gamma-32.7.11.10.465
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.465
2yee2ECHeat shock protein HSP 90-alpha/0.465
3d0bSNXHeat shock protein HSP 90-alpha/0.465
3r6xX84Cyclin-dependent kinase 22.7.11.220.465
3zkyWT4Isopenicillin N synthase1.21.3.10.465
4bb432WEphrin type-B receptor 42.7.10.10.465
4c6zTLE3-oxoacyl-ACP synthase/0.465
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4g1z0VPVitamin D3 receptor A/0.465
4loqSB4Mitogen-activated protein kinase 14/0.465
4o701QKBromodomain-containing protein 4/0.465
4prvADPDNA gyrase subunit B/0.465
1oirHDYCyclin-dependent kinase 22.7.11.220.464
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.464
2hr8SAHDiphthine synthase/0.464
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
3fln3FNMitogen-activated protein kinase 14/0.464
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.464
3qqfX07Cyclin-dependent kinase 22.7.11.220.464
3u2lFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.464
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.464
4ivd15TTyrosine-protein kinase JAK1/0.464
4lyn1YGCyclin-dependent kinase 22.7.11.220.464
4u7wNDPMxaA/0.464
5aaaVGHALK tyrosine kinase receptor2.7.10.10.464
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.464
5dt3ATPAurora kinase A2.7.11.10.464
1csnATPCasein kinase I homolog 12.7.11.10.463
1h1r6CPCyclin-dependent kinase 22.7.11.220.463
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.463
2c6tDT5Cyclin-dependent kinase 22.7.11.220.463
2fwyH64Heat shock protein HSP 90-alpha/0.463
2huvSAHDiphthine synthase/0.463
2r64740Cyclin-dependent kinase 22.7.11.220.463
2vbpVB1Isopenicillin N synthase1.21.3.10.463
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.463
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.463
2z2w770Wee1-like protein kinase2.7.10.20.463
3e5aVX6Aurora kinase A2.7.11.10.463
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.463
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.463
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.463
4ix4ADPUncharacterized protein/0.463
4men25KBromodomain-containing protein 4/0.463
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.463
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.463
5cwa0GAAnthranilate synthase component 14.1.3.270.463
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.463
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.462
1uycPU7Heat shock protein HSP 90-alpha/0.462
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.462
2emuSAHDiphthine synthase/0.462
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.462
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.462
2znq401Peroxisome proliferator-activated receptor delta/0.462
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.462
3op5REBSerine/threonine-protein kinase VRK12.7.11.10.462
3owj1ELCasein kinase II subunit alpha2.7.11.10.462
3r7eX88Cyclin-dependent kinase 22.7.11.220.462
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.462
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.462
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.462
4bj9UHBTankyrase-22.4.2.300.462
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.462
5eccNAPDehydrofolate reductase type I/0.462
1thnADPAnti-sigma F factor/0.461
1v1k3FPCyclin-dependent kinase 22.7.11.220.461
1vyw292Cyclin-dependent kinase 22.7.11.220.461
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.461
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
2gpuOHTEstrogen-related receptor gamma/0.461
2xvw9NRSerum albumin/0.461
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.461
2zbaZBATrichothecene 3-O-acetyltransferase/0.461
3gonANPPhosphomevalonate kinase/0.461
3lqfNADGalactitol dehydrogenase/0.461
3umw596Serine/threonine-protein kinase pim-12.7.11.10.461
3vt7VDXVitamin D3 receptor/0.461
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.461
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.461
4eooATPCyclin-dependent kinase 22.7.11.220.461
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4flpJQ1Bromodomain testis-specific protein/0.461
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.461
4mr41K0Bromodomain-containing protein 4/0.461
5dp2NAPCurF/0.461
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.460
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.460
2pzpACPFibroblast growth factor receptor 2/0.460
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.460
2wpa889Cyclin-dependent kinase 22.7.11.220.460
3ezrEZRCyclin-dependent kinase 22.7.11.220.460
3hl7I47Mitogen-activated protein kinase 14/0.460
3pl8FADPyranose 2-oxidase/0.460
3qqkX02Cyclin-dependent kinase 22.7.11.220.460
3zsi52PMitogen-activated protein kinase 14/0.460
4bcqTJFCyclin-dependent kinase 22.7.11.220.460
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.460
4fxfATPPyruvate kinase PKM2.7.1.400.460
4ix6ADPUncharacterized protein/0.460
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.460
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.460
1uyhPU0Heat shock protein HSP 90-alpha/0.459
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.459
2h55DZ8Heat shock protein HSP 90-alpha/0.459
2pb4SAHDiphthine synthase/0.459
2pmoHMDProtein kinase 7/0.459
3adaNADSubunit alpha of sarocosine oxidase/0.459
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3hx4ANPCalmodulin-domain protein kinase 1/0.459
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.459
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.459
3nww3NWMitogen-activated protein kinase 14/0.459
3rvhHQ2Lysine-specific demethylase 4A1.14.110.459
3s0o50ZCyclin-dependent kinase 22.7.11.220.459
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.459
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.459
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
4bgg844Activin receptor type-12.7.11.300.459
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.459
4g3rCAMCamphor 5-monooxygenase1.14.15.10.459
4mwhATPCasein kinase II subunit alpha2.7.11.10.459
4nh82LCHeat shock protein HSP 90-alpha/0.459
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
5e92ANPTGF-beta receptor type-22.7.11.300.459
1aq1STUCyclin-dependent kinase 22.7.11.220.458
1axwMTXThymidylate synthase/0.458
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.458
1qrpHH0Pepsin A-43.4.23.10.458
2eh4SAHDiphthine synthase/0.458
2ifaFMNUncharacterized protein/0.458
2po7CHDFerrochelatase, mitochondrial4.99.1.10.458
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.458
2uzeC95Cyclin-dependent kinase 22.7.11.220.458
2xvv9DNSerum albumin/0.458
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.458
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.458
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.458
3ns2PYVAbscisic acid receptor PYL2/0.458
3ocpCMPcGMP-dependent protein kinase 12.7.11.120.458
3oiaA31Camphor 5-monooxygenase1.14.15.10.458
3pxkPXKFocal adhesion kinase 12.7.10.20.458
4alhA9PBromodomain-containing protein 2/0.458
4b8mVX6Aurora kinase B-A2.7.11.10.458
4dgo0JWCasein kinase II subunit alpha2.7.11.10.458
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.458
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.458
4j0r1H2Bromodomain-containing protein 4/0.458
4kb81QNCasein kinase I isoform delta2.7.11.10.458
5drdATPAurora kinase A2.7.11.10.458
1a72PADAlcohol dehydrogenase E chain1.1.1.10.457
1aj22PHDihydropteroate synthase/0.457
1bwlFMNNADPH dehydrogenase 11.6.99.10.457
1diuBDMDihydrofolate reductase1.5.1.30.457
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.457
1ke7LS3Cyclin-dependent kinase 22.7.11.220.457
1m78NDPDihydrofolate reductase1.5.1.30.457
1oguST8Cyclin-dependent kinase 22.7.11.220.457
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.457
2q29ACOOxalyl-CoA decarboxylase4.1.1.80.457
2yemWSHBromodomain-containing protein 4/0.457
3a7hATPSerine/threonine-protein kinase 242.7.11.10.457
3at4CCKCasein kinase II subunit alpha2.7.11.10.457
3dds26BGlycogen phosphorylase, liver form2.4.1.10.457
3fznD7KBenzoylformate decarboxylase4.1.1.70.457
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.457
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.457
3lctADPALK tyrosine kinase receptor2.7.10.10.457
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.457
3o0iP54Heat shock protein HSP 90-alpha/0.457
3pdqKC6Lysine-specific demethylase 4A1.14.110.457
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4dymIYZActivin receptor type-12.7.11.300.457
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.457
4g47TZFMycocyclosin synthase1.14.21.90.457
4hvh19RTyrosine-protein kinase JAK32.7.10.20.457
4kbc1QJCasein kinase I isoform delta2.7.11.10.457
1e7aPFLSerum albumin/0.456
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.456
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.456
1r78FMDCyclin-dependent kinase 22.7.11.220.456
1uy6PU3Heat shock protein HSP 90-alpha/0.456
2bakAQZMitogen-activated protein kinase 14/0.456
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.456
2eglSAHDiphthine synthase/0.456
2fieA74Fructose-1,6-bisphosphatase 13.1.3.110.456
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.456
2qe4JJ3Estrogen receptor/0.456
2qg2A91Heat shock protein HSP 90-alpha/0.456
2xkeWI2Serine/threonine-protein kinase Nek22.7.11.10.456
3a62STURibosomal protein S6 kinase beta-12.7.11.10.456
3bheBZNGag-Pol polyprotein3.4.23.160.456
3ictFADCoenzyme A disulfide reductase/0.456
3s1dZIRCytokinin dehydrogenase 11.5.99.120.456
3v76FDAUncharacterized protein/0.456
4a9yAQZMitogen-activated protein kinase 14/0.456
4eor4SPCyclin-dependent kinase 22.7.11.220.456
4eqrCOACoenzyme A disulfide reductase/0.456
4g1d0VKVitamin D3 receptor A/0.456
4mv4ACPBiotin carboxylase6.3.4.140.456
4qmlANPSerine/threonine-protein kinase 242.7.11.10.456
4ugaH4BNitric oxide synthase oxygenase1.14.13.1650.456
5f0a1FBcGMP-dependent protein kinase, putative/0.456
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.455
1n83CLRNuclear receptor ROR-alpha/0.455
1synF89Thymidylate synthase/0.455
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.455
2en5SAHDiphthine synthase/0.455
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.455
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.455
2qo7ANPEphrin type-A receptor 32.7.10.10.455
2xneASHAurora kinase A2.7.11.10.455
2yjxYJXHeat shock protein HSP 90-alpha/0.455
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.455
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.455
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.455
4h1e10JBeta-secretase 13.4.23.460.455
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.455
4ktkKTKCytochrome P450/0.455
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.455
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.455
5auzGENDeath-associated protein kinase 12.7.11.10.455
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.454
1rkhVD2Vitamin D3 receptor/0.454
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.454
1uykPUXHeat shock protein HSP 90-alpha/0.454
1vyzN5BCyclin-dependent kinase 22.7.11.220.454
1wn3HXCPhenylacetic acid degradation protein PaaI/0.454
2c5nCK8Cyclin-dependent kinase 22.7.11.220.454
2hckQUETyrosine-protein kinase HCK2.7.10.20.454
2iw94SPCyclin-dependent kinase 22.7.11.220.454
2wi4ZZ4Heat shock protein HSP 90-alpha/0.454
2x7jTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.454
2yn8STUEphrin type-B receptor 42.7.10.10.454
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.454
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.454
3p67FMNPentaerythritol tetranitrate reductase/0.454
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.454
3r9hZ67Cyclin-dependent kinase 22.7.11.220.454
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.454
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.454
4e4m0NHTyrosine-protein kinase JAK2/0.454
4fkw62KCyclin-dependent kinase 22.7.11.220.454
4hxs1A3Bromodomain-containing protein 4/0.454
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.454
1c0lFADD-amino-acid oxidase1.4.3.30.453
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
1gy3ATPCyclin-dependent kinase 22.7.11.220.453
1ke9LS5Cyclin-dependent kinase 22.7.11.220.453
1m17AQ4Epidermal growth factor receptor2.7.10.10.453
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.453
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.453
2bu9HFVIsopenicillin N synthase1.21.3.10.453
2dwbANPAurora kinase A2.7.11.10.453
2i0ePDSProtein kinase C beta type2.7.11.130.453
2oji33AMitogen-activated protein kinase 12.7.11.240.453
2uxoTACHTH-type transcriptional regulator TtgR/0.453
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.453
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.453
3frqERYErythromycin resistance repressor protein/0.453
3gxlQIGTGF-beta receptor type-12.7.11.300.453
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.453
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.453
3phjDHKShikimate dehydrogenase (NADP(+))/0.453
3qwkX62Cyclin-dependent kinase 22.7.11.220.453
3ti1B49Cyclin-dependent kinase 22.7.11.220.453
3w551FMMitogen-activated protein kinase 12.7.11.240.453
4c58824Cyclin-G-associated kinase2.7.11.10.453
4cfnJYMCyclin-dependent kinase 22.7.11.220.453
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
4eok4SPCyclin-dependent kinase 22.7.11.220.453
4ez30S0Cyclin-dependent kinase 22.7.11.220.453
4f3gKAIGlutamate receptor 3/0.453
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.453
4hnc0UTMandelate racemase/0.453
4ix5ANPUncharacterized protein/0.453
4jr7GNPCasein kinase II subunit alpha2.7.11.10.453
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.453
4py6R78Bromodomain protein, putative/0.453
5bukFADFADH2-dependent halogenase/0.453
1bygSTUTyrosine-protein kinase CSK/0.452
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.452
1jtqLY3Thymidylate synthase/0.452
2e07SAHDiphthine synthase/0.452
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.452
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.452
2np8CC3Aurora kinase A2.7.11.10.452
2owkSAHDiphthine synthase/0.452
2rg5279Mitogen-activated protein kinase 14/0.452
2vwqNAPGlucose 1-dehydrogenase/0.452
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.452
2ym1FADPhenylacetone monooxygenase1.14.13.920.452
2zjwREFCasein kinase II subunit alpha2.7.11.10.452
3du8553Glycogen synthase kinase-3 beta2.7.11.260.452
3fbsFADOxidoreductase/0.452
3gb4D3MDdmC/0.452
3oafOAGDihydrofolate reductase1.5.1.30.452
3p79P79Mitogen-activated protein kinase 14/0.452
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.452
3v0tATRPerakine reductase1.1.1.3170.452
3vt8YI3Vitamin D3 receptor/0.452
4a9mP9MBromodomain-containing protein 2/0.452
4eos1ROCyclin-dependent kinase 22.7.11.220.452
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.452
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.452
5e8xSTUTGF-beta receptor type-12.7.11.300.452
1dkfBMSRetinoic acid receptor alpha/0.451
1dr5NAPDihydrofolate reductase1.5.1.30.451
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.451
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1oc1ASVIsopenicillin N synthase1.21.3.10.451
1qiqACCIsopenicillin N synthase1.21.3.10.451
1xjdSTUProtein kinase C theta type2.7.11.130.451
2gtnLIEMitogen-activated protein kinase 14/0.451
2pcaSAHDiphthine synthase/0.451
2pmdGNPTranslation initiation factor 2 subunit gamma/0.451
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.451
2r1rTTPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.451
2yac937Serine/threonine-protein kinase PLK12.7.11.210.451
2ykiYKIHeat shock protein HSP 90-alpha/0.451
2znnS44Peroxisome proliferator-activated receptor alpha/0.451
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.451
3gbuATPUncharacterized sugar kinase PH14592.7.10.451
3l0lHC3Nuclear receptor ROR-gamma/0.451
3mvl38PMitogen-activated protein kinase 14/0.451
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.451
3nj0PYVAbscisic acid receptor PYL2/0.451
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.451
3zep1NXTyrosine-protein kinase JAK32.7.10.20.451
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.451
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.451
4dpy2P0Mevalonate diphosphate decarboxylase/0.451
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.451
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.451
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.451
4ia1BIVVitamin D3 receptor A/0.451
4j0v1H7Beta-secretase 13.4.23.460.451
4uyf73BBromodomain-containing protein 2/0.451
1tehNADAlcohol dehydrogenase class-31.1.1.10.450
1uy7PU4Heat shock protein HSP 90-alpha/0.450
1vrwNAIEnoyl-ACP reductase/0.450
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
2ovmAS0Progesterone receptor/0.450
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.450
2py3ACPFibroblast growth factor receptor 2/0.450
2vwz7X6Ephrin type-B receptor 42.7.10.10.450
2wi72KLHeat shock protein HSP 90-alpha/0.450
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.450
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.450
3dogNNNCyclin-dependent kinase 22.7.11.220.450
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3hz142CHeat shock protein HSP 90-alpha/0.450
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3lsiFADPyranose 2-oxidase/0.450
3ql8X01Cyclin-dependent kinase 22.7.11.220.450
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.450
3t2zFADSulfide-quinone reductase/0.450
3tm5SFGUncharacterized protein/0.450
3vf80JETyrosine-protein kinase SYK2.7.10.20.450
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.450
4da8BG2Purine nucleoside phosphorylase DeoD-type2.4.2.10.450
4jqeANPCasein kinase II subunit alpha2.7.11.10.450
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.450
3uzaT4GAdenosine receptor A2a/0.450
1g28FMNPHY3/0.449
1ir3ANPInsulin receptor2.7.10.10.449
1lbbKAIGlutamate receptor 2/0.449
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.449
1udaUFGUDP-glucose 4-epimerase5.1.3.20.449
1w1rZEACytokinin dehydrogenase 11.5.99.120.449
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.449
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.449
2cig1DGDihydrofolate reductase1.5.1.30.449
2dv5SAHDiphthine synthase/0.449
2eh5SAHDiphthine synthase/0.449
2ijmATPFocal adhesion kinase 12.7.10.20.449
2j0vGDPRac-like GTP-binding protein ARAC7/0.449
2op18PCEnoyl-ACP reductase/0.449
3dt1P40Mitogen-activated protein kinase 14/0.449
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.449
3r8zZ63Cyclin-dependent kinase 22.7.11.220.449
3s79ASDAromatase1.14.14.140.449
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.449
4brxKGWFocal adhesion kinase 12.7.10.20.449
4dtbGMPAPH(2'')-Id/0.449
4ead0NPThymidine phosphorylase2.4.2.40.449
4iaq2GM5-hydroxytryptamine receptor 1B/0.449
4j3i1K0Bromodomain-containing protein 4/0.449
4l2oNADAldehyde dehydrogenase, dimeric NADP-preferring/0.449
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.449
5auwQUEDeath-associated protein kinase 12.7.11.10.449
5dt0SKEAurora kinase A2.7.11.10.449
1dfoFFOSerine hydroxymethyltransferase2.1.2.10.448
1eh4IC1Casein kinase I homolog 12.7.11.10.448
1kzjCB3Thymidylate synthase/0.448
1m75CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.448
1unhIXMCyclin-dependent-like kinase 52.7.11.10.448
1uzwCDHIsopenicillin N synthase1.21.3.10.448
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.448
2c5yMTWCyclin-dependent kinase 22.7.11.220.448
2chlDKICasein kinase I isoform gamma-32.7.11.10.448
2e16SAHDiphthine synthase/0.448
2etm7PYFocal adhesion kinase 12.7.10.20.448
2harOCCVitamin D3 receptor/0.448
2hk51BMTyrosine-protein kinase HCK2.7.10.20.448
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.448
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.448
2vgoAD5Aurora kinase B-A2.7.11.10.448
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.448
2yekEAMBromodomain-containing protein 2/0.448
3cqeP91Wee1-like protein kinase2.7.10.20.448
3ixp834Ecdysone receptor/0.448
3kjm245Cytokinin dehydrogenase 11.5.99.120.448
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.448
3o6o94MHeat shock protein 83/0.448
3oom507Activin receptor type-12.7.11.300.448
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.448
3owsEQUSteroid Delta-isomerase5.3.3.10.448
3rm719ZCyclin-dependent kinase 22.7.11.220.448
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.448
4cegADPAurora kinase A2.7.11.10.448
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4fhh0U3Vitamin D3 receptor A/0.448
4fkq42KCyclin-dependent kinase 22.7.11.220.448
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.448
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.448
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
4xgxADPFAD:protein FMN transferase/0.448
1c4yIH3Prothrombin3.4.21.50.447
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.447
1nzfUPGDNA beta-glucosyltransferase/0.447
1rbyKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.447
1upw444Oxysterols receptor LXR-beta/0.447
1uyfPU1Heat shock protein HSP 90-alpha/0.447
1veaHBNHut operon positive regulatory protein/0.447
1x2hLPALipoate-protein ligase A6.3.1.200.447
2emrSAHDiphthine synthase/0.447
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.447
2vr1ATFBiotin carboxylase6.3.4.140.447
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
2y0mACOHistone acetyltransferase KAT8/0.447
2y6fM9FIsopenicillin N synthase1.21.3.10.447
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.447
2yk2YJWHeat shock protein HSP 90-alpha/0.447
3n0tOPYDipeptidyl peptidase 23.4.14.20.447
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.447
3q5iANPProtein kinase, putative/0.447
4a4l939Serine/threonine-protein kinase PLK12.7.11.210.447
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.447
4e1z0MXNon-receptor tyrosine-protein kinase TYK22.7.10.20.447
4f630S7Fibroblast growth factor receptor 1/0.447
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.447
4fko20KCyclin-dependent kinase 22.7.11.220.447
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.447
4jbqVX6Aurora kinase A2.7.11.10.447
4k9yK9YFocal adhesion kinase 12.7.10.20.447
4o74R78Bromodomain-containing protein 4/0.447
4tx9AMZPhosphoribosyl isomerase A/0.447
4u8iFDAUDP-galactopyranose mutase/0.447
3sn6P0GBeta-2 adrenergic receptor/0.447
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.446
1m76CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
1o2g696Prothrombin3.4.21.50.446
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.446
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.446
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
1u54ACPActivated CDC42 kinase 1/0.446
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.446
2egsSAHDiphthine synthase/0.446
2ekaSAHDiphthine synthase/0.446
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.446
2jfz003Glutamate racemase/0.446
2p5fSAHDiphthine synthase/0.446
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.446
2w1eL0EAurora kinase A2.7.11.10.446
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.446
2x9fX9FEphrin type-B receptor 42.7.10.10.446
2xf3J01Uncharacterized protein/0.446
3fwfCAMCamphor 5-monooxygenase1.14.15.10.446
3fwjCAMCamphor 5-monooxygenase1.14.15.10.446
3gwlFADFAD-linked sulfhydryl oxidase1.8.3.20.446
3inxJZCHeat shock protein HSP 90-alpha/0.446
3nr4PYVAbscisic acid receptor PYL2/0.446
3p9tTCLRepressor/0.446
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.446
3qziX72Cyclin-dependent kinase 22.7.11.220.446
3sf6FDAGlutaryl-CoA dehydrogenase/0.446
4aknS5BBromodomain-containing protein 2/0.446
4b8zNAPGDP-L-fucose synthase1.1.1.2710.446
4bcoT6QCyclin-dependent kinase 22.7.11.220.446
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.446
4fkv61KCyclin-dependent kinase 22.7.11.220.446
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.446
4gk3L87Ephrin type-A receptor 32.7.10.10.446
4m2xTMQDihydrofolate reductase1.5.1.30.446
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.446
4tuvCPZCytochrome P450 1191.140.446
4xq9NADHomospermidine synthase2.5.1.440.446
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.446
6cp4CAMCamphor 5-monooxygenase1.14.15.10.446
1h74ADPHomoserine kinase2.7.1.390.445
1ju6LYAThymidylate synthase2.1.1.450.445
1ogxEQUSteroid Delta-isomerase5.3.3.10.445
1p2a5BNCyclin-dependent kinase 22.7.11.220.445
1uydPU8Heat shock protein HSP 90-alpha/0.445
1v0pPVBCell division control protein 2 homolog2.7.11.220.445
2d2iNAPGlyceraldehyde-3-phosphate dehydrogenase/0.445
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.445
2oo5TXDNAD(P) transhydrogenase subunit alpha part 11.6.1.20.445
2p2jPRXAcetyl-coenzyme A synthetase/0.445
2p7zOHTEstrogen-related receptor gamma/0.445
2pmlANPUncharacterized protein/0.445
2q7vFADThioredoxin reductase/0.445
2w17I19Cyclin-dependent kinase 22.7.11.220.445
2xk3XK3Serine/threonine-protein kinase Nek22.7.11.10.445
3a7jADPSerine/threonine-protein kinase 242.7.11.10.445
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.445
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.445
3ctj320Hepatocyte growth factor receptor2.7.10.10.445
3hz5Z64Heat shock protein HSP 90-alpha/0.445
3nf8CDQGag-Pol polyprotein/0.445
3pqbVGPPutative oxidoreductase/0.445
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3r7iX9ICyclin-dependent kinase 22.7.11.220.445
3s7a684Dihydrofolate reductase1.5.1.30.445
3t1tGDPProbable gliding protein mglA/0.445
3vjoANPEpidermal growth factor receptor2.7.10.10.445
3zraORBProgesterone receptor/0.445
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.445
4dbzNDPPutative ketoacyl reductase1.3.10.445
4dphP65Bifunctional dihydrofolate reductase-thymidylate synthase/0.445
4eilUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
4fv7E94Mitogen-activated protein kinase 12.7.11.240.445
4hnf16WCasein kinase I isoform delta2.7.11.10.445
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.445
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.445
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.445
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.445
4jq7KJQEpidermal growth factor receptor2.7.10.10.445
4lvg20ONicotinamide phosphoribosyltransferase2.4.2.120.445
4mr61K0Bromodomain-containing protein 2/0.445
4pkl1GHUncharacterized protein/0.445
4riyADPEpidermal growth factor receptor2.7.10.10.445
4twnB96Ephrin type-A receptor 32.7.10.10.445
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.445
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.445
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1lquNDPNADPH-ferredoxin reductase FprA1.18.1.20.444
2balPQAMitogen-activated protein kinase 14/0.444
2c6iDT1Cyclin-dependent kinase 22.7.11.220.444
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.444
2ek4SAHDiphthine synthase/0.444
2fwzH71Heat shock protein HSP 90-alpha/0.444
2oyfIACBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.444
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.444
2qpyDHTAndrogen receptor/0.444
2w3wVG9Dihydrofolate reductase/0.444
3flzFLZMitogen-activated protein kinase 14/0.444
3mnrSD1Heat shock protein HSP 90-alpha/0.444
3owl19ECasein kinase II subunit alpha2.7.11.10.444
3pgiF41Endothiapepsin3.4.23.220.444
3qzfX66Cyclin-dependent kinase 22.7.11.220.444
3sqq99ZCyclin-dependent kinase 22.7.11.220.444
3unk0BYCyclin-dependent kinase 22.7.11.220.444
3vt5YI2Vitamin D3 receptor/0.444
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.444
4eji0QACytochrome P450 2A131.14.14.10.444
4h3ySAHtRNA (guanine-N(1)-)-methyltransferase/0.444
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.444
4nj32KDCyclin-dependent kinase 22.7.11.220.444
4rvnCOAPhenylacetate-coenzyme A ligase/0.444
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.444
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.444
5auvAGIDeath-associated protein kinase 12.7.11.10.444
5dr2ATPAurora kinase A2.7.11.10.444
5l8kADPAurora kinase A2.7.11.10.444
1a59COA2-methylcitrate synthase/0.443
1dssNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.443
1eyqNARChalcone--flavonone isomerase 15.5.1.60.443
1f4gTP4Thymidylate synthase/0.443
1hiiC20Gag-Pol polyprotein/0.443
1i58ACPChemotaxis protein CheA2.7.13.30.443
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.443
1py5PY1TGF-beta receptor type-12.7.11.300.443
1xddAAYIntegrin alpha-L/0.443
2b7aIZATyrosine-protein kinase JAK2/0.443
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.443
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.443
2dv4SAHDiphthine synthase/0.443
2e8qSAHDiphthine synthase/0.443
2h39ADQADP-glucose phosphorylase/0.443
2j0k4STFocal adhesion kinase 12.7.10.20.443
2pulACPMethylthioribose kinase2.7.1.1000.443
2qnqQN3Gag-Pol polyprotein3.4.23.160.443
2uxhQUEHTH-type transcriptional regulator TtgR/0.443
2vwx7X4Ephrin type-B receptor 42.7.10.10.443
3bhy7CPDeath-associated protein kinase 3/0.443
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.443
3hz137DHeat shock protein HSP 90-alpha/0.443
3i6iNDPPutative leucoanthocyanidin reductase 1/0.443
3imgBZ2Pantothenate synthetase6.3.2.10.443
3is9AC7Gag-Pol polyprotein2.7.7.490.443
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.443
3owuEQUSteroid Delta-isomerase5.3.3.10.443
3p6pA6BCamphor 5-monooxygenase1.14.15.10.443
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.443
3qxoX65Cyclin-dependent kinase 22.7.11.220.443
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.443
3wsbRWZFarnesyltransferase, putative/0.443
4aacAAVMitogen-activated protein kinase 14/0.443
4appN53Serine/threonine-protein kinase PAK 42.7.11.10.443
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.443
4g2gTDHMycocyclosin synthase1.14.21.90.443
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.443
4jq8KJ8Epidermal growth factor receptor2.7.10.10.443
4k6z1Q3Tyrosine-protein kinase JAK1/0.443
4kiq1RAMitogen-activated protein kinase 14/0.443
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.443
4r1lADPPhenylacetate-coenzyme A ligase/0.443
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.443
1agwSU2Fibroblast growth factor receptor 1/0.442
1dhrNADDihydropteridine reductase1.5.1.340.442
1f4fTP3Thymidylate synthase/0.442
1fvt106Cyclin-dependent kinase 22.7.11.220.442
1ix1BB2Peptide deformylase/0.442
1ke6LS2Cyclin-dependent kinase 22.7.11.220.442
1mvsDTMDihydrofolate reductase1.5.1.30.442
1nooCAHCamphor 5-monooxygenase1.14.15.10.442
1p0pBCHCholinesterase3.1.1.80.442
1p4fDRGDeath-associated protein kinase 12.7.11.10.442
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.442
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.442
2btsU32Cyclin-dependent kinase 22.7.11.220.442
2cjpVPREpoxide hydrolase/0.442
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.442
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.442
2puiADPMethylthioribose kinase2.7.1.1000.442
2wggTLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.442
2x81ZZLAurora kinase A2.7.11.10.442
2xk6EQHSerine/threonine-protein kinase Nek22.7.11.10.442
2yk2YJXHeat shock protein HSP 90-alpha/0.442
3at3ATKCasein kinase II subunit alpha2.7.11.10.442
3br3ETHTH-type transcriptional regulator QacR/0.442
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.442
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.442
3mgdACOPredicted acetyltransferase/0.442
3q5kD1UHeat shock protein 83-1/0.442
3sdkP3NProteasome subunit beta type-53.4.25.10.442
3sdkP3NProteasome subunit beta type-63.4.25.10.442
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.442
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.442
3wmxNADNAD dependent epimerase/dehydratase/0.442
3wrhCAMCamphor 5-monooxygenase1.14.15.10.442
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.442
4bdoKAIGlutamate receptor ionotropic, kainate 2/0.442
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.442
4ia3BIVVitamin D3 receptor A/0.442
4mr51K0Bromodomain-containing protein 2/0.442
4nb6444Nuclear receptor ROR-gamma/0.442
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.442
4nr52LLCREB-binding protein/0.442
4qppSAHProtein arginine N-methyltransferase 6/0.442
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1gvt2ZSEndothiapepsin3.4.23.220.441
1j39UPGDNA beta-glucosyltransferase/0.441
1jujLYAThymidylate synthase2.1.1.450.441
1nqmBTNStreptavidin/0.441
1oqcFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.441
1q1rFADPutidaredoxin reductase1.18.1.50.441
1uymPU3Heat shock protein HSP 90-beta/0.441
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.441
1ykr628Cyclin-dependent kinase 22.7.11.220.441
2e0nSAHPrecorrin-2 C20-methyltransferase/0.441
2ejkSAHDiphthine synthase/0.441
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.441
2ok7FADFerredoxin--NADP reductase, apicoplast/0.441
2pchSAHDiphthine synthase/0.441
2vwy7X5Ephrin type-B receptor 42.7.10.10.441
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.441
2z0ySAMRibosomal RNA small subunit methyltransferase E/0.441
2zaxCAMCamphor 5-monooxygenase1.14.15.10.441
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.441
3ac2KSETyrosine-protein kinase Lck2.7.10.20.441
3beaIXHMacrophage colony-stimulating factor 1 receptor2.7.10.10.441
3btoSSBAlcohol dehydrogenase E chain1.1.1.10.441
3cluFADElectron transfer flavoprotein subunit alpha/0.441
3d76NBBPheromone-binding protein ASP1/0.441
3kytHC2Nuclear receptor ROR-gamma/0.441
3lpbNVBTyrosine-protein kinase JAK2/0.441
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.441
3orkAGSSerine/threonine protein kinase/0.441
3qu0X40Cyclin-dependent kinase 22.7.11.220.441
3s00Z60Cyclin-dependent kinase 22.7.11.220.441
3tjsD0RCytochrome P450 3A4/0.441
4anmWULCasein kinase II subunit alpha2.7.11.10.441
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.441
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.441
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.441
4gk2L66Ephrin type-A receptor 32.7.10.10.441
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.441
4l8u9AZSerum albumin/0.441
4lxhC1EAlpha/beta hydrolase fold/0.441
4o0sADNAurora kinase A2.7.11.10.441
4r9uANPVitamin B12 import ATP-binding protein BtuD/0.441
1ay0TPPTransketolase 12.2.1.10.440
1eqbFFOSerine hydroxymethyltransferase2.1.2.10.440
1jtuLYBThymidylate synthase/0.440
1ml6GBXGlutathione S-transferase A22.5.1.180.440
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1u28NAPNAD(P) transhydrogenase subunit beta1.6.1.20.440
1uyePU9Heat shock protein HSP 90-alpha/0.440
1xjjDGTVitamin B12-dependent ribonucleotide reductase/0.440
2bgiFADNADPH:ferredoxin reductase/0.440
2br5SAHCephalosporin hydroxylase CmcI/0.440
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.440
2givACOHistone acetyltransferase KAT8/0.440
2hb8MVDVitamin D3 receptor/0.440
2io6330Wee1-like protein kinase2.7.10.20.440
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.440
2pcmSAHDiphthine synthase/0.440
2qblCAMCamphor 5-monooxygenase1.14.15.10.440
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.440
2xyuQ9GEphrin type-A receptor 42.7.10.10.440
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.440
2ykeYKEHeat shock protein HSP 90-alpha/0.440
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.440
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.440
3da24MDCarbonic anhydrase 134.2.1.10.440
3ddqRRCCyclin-dependent kinase 22.7.11.220.440
3fklFKLMitogen-activated protein kinase 14/0.440
3hyz42CHeat shock protein HSP 90-alpha/0.440
3jpuTY4Transcriptional activator protein LasR/0.440
3kf7L9GMitogen-activated protein kinase 14/0.440
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.440
3qpvADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.440
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.440
3t4hMD5Alpha-ketoglutarate-dependent dioxygenase AlkB1.14.11.330.440
3tk3CPZCytochrome P450 2B41.14.14.10.440
3tnlNADShikimate dehydrogenase (NADP(+))/0.440
3upi0C2Genome polyprotein2.7.7.480.440
3uzp0CKCasein kinase I isoform delta2.7.11.10.440
3zuxTCHTransporter/0.440
4at2ASDPossible succinate dehydrogenase/0.440
4bjx73BBromodomain-containing protein 4/0.440
4c57FEFCyclin-G-associated kinase2.7.11.10.440
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.440
4dxd9PCCell division protein FtsZ/0.440
4gqkADPActin cross-linking toxin VgrG1/0.440
4j97ACPFibroblast growth factor receptor 2/0.440
4kaoKAOFocal adhesion kinase 12.7.10.20.440
4ogiR78Bromodomain-containing protein 4/0.440
4rr6A3SProbable threonine--tRNA ligase 26.1.1.30.440
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.440
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.440
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.440
5auxKMPDeath-associated protein kinase 12.7.11.10.440
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.440
5koiNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440