sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	tRNA (guanine-N(1)-)-methyltransferase
ID:	TRMD_PARP8
AC:	B2JF31
Organism:	Paraburkholderia phymatum
Reign:	Bacteria
TaxID:	391038
EC Number:	/

---

Chains:

Chain Name:	Percentage of Residues within binding site
A	80 %
B	20 %

---

Ligand binding site composition:

B-Factor:	35.282
Number of residues:	36
Including
Standard Amino Acids:	35
Non Standard Amino Acids:	0
Water Molecules:	1
Cofactors:
Metals:

---

Cavity properties

Ligandability	Volume (Å3)
1.306	1292.625

% Hydrophobic	% Polar
45.17	54.83
According to VolSite

HET Code:	SAH
Formula:	C14H20N6O5S
Molecular weight:	384.411 g/mol
DrugBank ID:	DB01752
Buried Surface Area:	71.55 %
Polar Surface area:	212.38 Å2

Number of
H-Bond Acceptors:	10
H-Bond Donors:	4
Rings:	3
Aromatic rings:	2
Anionic atoms:	1
Cationic atoms:	1
Rule of Five Violation:	1
Rotatable Bonds:	7

---

Mass center Coordinates

X	Y	Z
-1.50888	-37.6988	-11.3297

• 2D View
• 3D View