Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
3tqb | FOL | Dihydrofolate reductase |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
3tqb | FOL | Dihydrofolate reductase | / | 1.000 | |
3tq9 | MTX | Dihydrofolate reductase | / | 0.769 | |
1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.648 | |
1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.647 | |
3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.627 | |
3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.626 | |
3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.624 | |
3jwc | EKB | Dihydrofolate reductase | / | 0.622 | |
3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.618 | |
3qly | 55V | Uncharacterized protein | / | 0.614 | |
4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.612 | |
1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.609 | |
4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.606 | |
3cse | N22 | Uncharacterized protein | / | 0.605 | |
7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.604 | |
3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.600 | |
1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.598 | |
1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.595 | |
3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.595 | |
3sa1 | 6DR | Dihydrofolate reductase | / | 0.595 | |
1df7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.593 | |
3qlz | QLZ | Uncharacterized protein | / | 0.593 | |
3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.592 | |
1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.591 | |
1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.590 | |
3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.590 | |
3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.590 | |
1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.589 | |
3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.588 | |
1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.586 | |
4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.585 | |
2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.583 | |
3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.583 | |
3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.583 | |
3jw5 | TOP | Dihydrofolate reductase | / | 0.583 | |
3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.583 | |
2w3v | TOP | Dihydrofolate reductase | / | 0.582 | |
3ia4 | MTX | Dihydrofolate reductase | / | 0.582 | |
2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.581 | |
2zza | FOL | Dihydrofolate reductase | / | 0.579 | |
3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.578 | |
1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.577 | |
5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.577 | |
3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.576 | |
1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.575 | |
4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.574 | |
3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.573 | |
1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.572 | |
3eek | 53S | Uncharacterized protein | / | 0.572 | |
1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.571 | |
3dat | MTX | Dihydrofolate reductase | / | 0.571 | |
4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.571 | |
1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.570 | |
3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.570 | |
3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.569 | |
4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.569 | |
1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.568 | |
2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.568 | |
3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.568 | |
1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.567 | |
2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.567 | |
3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.567 | |
4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.567 | |
3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.566 | |
4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.566 | |
2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.565 | |
3fra | I2H | Dihydrofolate reductase | 1.5.1.3 | 0.565 | |
4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.565 | |
3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.564 | |
4p66 | MTX | Dihydrofolate reductase | / | 0.564 | |
1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.563 | |
2qk8 | MTX | Dihydrofolate reductase | / | 0.563 | |
4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.563 | |
4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.563 | |
1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.561 | |
3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.561 | |
3eem | 53V | Uncharacterized protein | / | 0.561 | |
3fyv | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.561 | |
3jwm | 5WB | Dihydrofolate reductase | / | 0.561 | |
4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.561 | |
1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.560 | |
3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.560 | |
4elb | 34S | Dihydrofolate reductase | / | 0.560 | |
1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.559 | |
2w9g | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.556 | |
3eej | 53R | Uncharacterized protein | / | 0.556 | |
3fre | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.556 | |
4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.556 | |
1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.555 | |
2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.554 | |
3gi2 | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.554 | |
3r33 | 6ME | Dihydrofolate reductase | 1.5.1.3 | 0.554 | |
1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.553 | |
3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.553 | |
4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.553 | |
1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.552 | |
3qlx | QLR | Uncharacterized protein | / | 0.551 | |
1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.550 | |
1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.550 | |
1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.549 | |
2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.549 | |
3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.549 | |
3qyo | Q24 | Dihydrofolate reductase | 1.5.1.3 | 0.549 | |
4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.548 | |
4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.547 | |
3sai | 9DR | Dihydrofolate reductase | / | 0.546 | |
1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.545 | |
1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.544 | |
1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.544 | |
3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.543 | |
3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.542 | |
1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.540 | |
3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.540 | |
3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.538 | |
4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.538 | |
3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.536 | |
3eel | 53T | Uncharacterized protein | / | 0.536 | |
3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.536 | |
3sa2 | 7DR | Dihydrofolate reductase | / | 0.536 | |
4ele | 31I | Dihydrofolate reductase | / | 0.536 | |
1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.535 | |
3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.535 | |
3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.535 | |
3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.534 | |
3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.534 | |
2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.532 | |
1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.531 | |
1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.531 | |
4m7v | RAR | Dihydrofolate reductase | / | 0.528 | |
1u72 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.527 | |
2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.527 | |
4elb | 34R | Dihydrofolate reductase | / | 0.527 | |
1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.524 | |
1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.523 | |
1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.523 | |
3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.523 | |
3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.522 | |
4elh | 53I | Dihydrofolate reductase | / | 0.522 | |
3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.521 | |
3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.521 | |
3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.521 | |
1rg7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.520 | |
4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.520 | |
1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.518 | |
3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.518 | |
1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
5ecc | NAP | Dehydrofolate reductase type I | / | 0.515 | |
3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.513 | |
4elf | 35I | Dihydrofolate reductase | / | 0.513 | |
4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.511 | |
3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.511 | |
4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.511 | |
4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.511 | |
4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.511 | |
1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.510 | |
4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.510 | |
4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.510 | |
1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.509 | |
3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.508 | |
3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.508 | |
1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
3fl9 | TOP | Dihydrofolate reductase | / | 0.505 | |
3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.504 | |
4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.503 | |
3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
1kce | CB3 | Thymidylate synthase | / | 0.502 | |
3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.502 | |
1rx2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.501 | |
1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.500 | |
4iv2 | 1GR | Estrogen receptor | / | 0.500 | |
5hi6 | MTX | Dihydrofolate reductase | / | 0.500 | |
1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.499 | |
3fl8 | RAR | Dihydrofolate reductase | / | 0.499 | |
3tq8 | TOP | Dihydrofolate reductase | / | 0.499 | |
4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.498 | |
3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.498 | |
1olm | VTQ | SEC14-like protein 2 | / | 0.496 | |
3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.496 | |
2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.493 | |
3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.493 | |
4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.493 | |
2tsc | CB3 | Thymidylate synthase | / | 0.492 | |
1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.491 | |
2p15 | EZT | Estrogen receptor | / | 0.491 | |
4j6d | TES | Cytochrome P450 monooxygenase | / | 0.491 | |
4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
3njo | PYV | Abscisic acid receptor PYR1 | / | 0.490 | |
4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.490 | |
4twp | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.490 | |
5d7p | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.490 | |
4o71 | CPB | Bromodomain-containing protein 4 | / | 0.489 | |
3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.488 | |
3g8d | ADP | Biotin carboxylase | 6.3.4.14 | 0.488 | |
3m09 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
4j6c | STR | Cytochrome P450 monooxygenase | / | 0.487 | |
1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
3gwf | NAP | Cyclohexanone monooxygenase | / | 0.485 | |
1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.483 | |
1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.483 | |
3tda | PN0 | Cytochrome P450 2D6 | / | 0.483 | |
4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.483 | |
4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.483 | |
4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
4l9q | 9TP | Serum albumin | / | 0.483 | |
1n4h | REA | Nuclear receptor ROR-beta | / | 0.482 | |
1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.482 | |
5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.482 | |
1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.481 | |
1og5 | SWF | Cytochrome P450 2C9 | / | 0.481 | |
3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
4ia1 | BIV | Vitamin D3 receptor A | / | 0.481 | |
4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.481 | |
1rd4 | L08 | Integrin alpha-L | / | 0.480 | |
1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
2w3w | VG9 | Dihydrofolate reductase | / | 0.480 | |
1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.479 | |
2z3u | CRR | Cytochrome P450 | / | 0.479 | |
3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.479 | |
3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.479 | |
4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.479 | |
4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.478 | |
2qe4 | JJ3 | Estrogen receptor | / | 0.478 | |
3a1l | 2CC | Cytochrome P450 | / | 0.478 | |
3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.478 | |
3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.478 | |
3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.478 | |
4iw8 | KN3 | Estrogen receptor | / | 0.478 | |
4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.478 | |
4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.478 | |
4p68 | MTX | Dihydrofolate reductase | / | 0.478 | |
4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.477 | |
5bp9 | SAH | Putative methyltransferase protein | / | 0.477 | |
2bbq | PFG | Thymidylate synthase | / | 0.476 | |
4gkt | 0O1 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.476 | |
1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.475 | |
2x20 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.475 | |
2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.475 | |
3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
3p9t | TCL | Repressor | / | 0.475 | |
4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.475 | |
4iui | 1GQ | Estrogen receptor | / | 0.475 | |
4p6w | MOF | Glucocorticoid receptor | / | 0.475 | |
1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.474 | |
2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.474 | |
2d0k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.474 | |
4j7u | YTZ | Sepiapterin reductase | 1.1.1.153 | 0.474 | |
1kzj | CB3 | Thymidylate synthase | / | 0.473 | |
1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.473 | |
2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.473 | |
3d77 | NBB | Pheromone-binding protein ASP1 | / | 0.473 | |
3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.473 | |
4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.473 | |
4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.473 | |
1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
1l2i | ETC | Estrogen receptor | / | 0.472 | |
1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.471 | |
1fmj | RTL | Retinol dehydratase | / | 0.471 | |
1tl1 | H18 | Gag-Pol polyprotein | 2.7.7.49 | 0.471 | |
2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.471 | |
2gq3 | COA | Malate synthase G | / | 0.471 | |
2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.471 | |
2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.471 | |
3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.471 | |
3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.471 | |
3ibq | ATP | Pyridoxal kinase | / | 0.471 | |
3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
3v1m | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.471 | |
4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.471 | |
4dhy | S41 | Glucokinase | 2.7.1.2 | 0.471 | |
1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
1r2j | FAD | FkbI | / | 0.470 | |
1tl3 | H20 | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.470 | |
3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.470 | |
3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.470 | |
3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.470 | |
4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
4o95 | 245 | Cytokinin dehydrogenase 4 | / | 0.470 | |
5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.470 | |
1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.469 | |
1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
1tkt | H12 | Gag-Pol polyprotein | 2.7.7.49 | 0.469 | |
1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.469 | |
2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.469 | |
2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.469 | |
3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.469 | |
3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
4ia7 | BIV | Vitamin D3 receptor A | / | 0.469 | |
4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.469 | |
1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.468 | |
3njo | P2M | Abscisic acid receptor PYR1 | / | 0.468 | |
4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.468 | |
5jad | FB2 | Platelet-activating factor acetylhydrolase | 3.1.1.47 | 0.468 | |
1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.467 | |
1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.467 | |
2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.467 | |
3vt7 | VDX | Vitamin D3 receptor | / | 0.467 | |
4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.466 | |
1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
1n71 | COA | Aac(6')-Ii protein | / | 0.466 | |
1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.466 | |
1tkz | H16 | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
2hb8 | MVD | Vitamin D3 receptor | / | 0.466 | |
2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.466 | |
2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.466 | |
3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.466 | |
4lt6 | 3AT | Poly(A) polymerase gamma | 2.7.7.19 | 0.466 | |
1dre | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
1fml | RTL | Retinol dehydratase | / | 0.465 | |
1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.465 | |
1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.465 | |
2fmn | 4HF | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.465 | |
2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.465 | |
2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.465 | |
2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.465 | |
2w0h | NDP | Trypanothione reductase | / | 0.465 | |
2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.465 | |
3fsu | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.465 | |
3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.465 | |
4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.465 | |
4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.465 | |
4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.465 | |
1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
1dkf | BMS | Retinoic acid receptor alpha | / | 0.464 | |
1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.464 | |
2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.464 | |
2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.464 | |
2vg7 | NNI | Gag-Pol polyprotein | 2.7.7.49 | 0.464 | |
2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.464 | |
3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.464 | |
3jpv | 1DR | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
3rl3 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.464 | |
3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.464 | |
4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.464 | |
1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.463 | |
1nce | CB3 | Thymidylate synthase | / | 0.463 | |
1rh3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
1rt7 | UC4 | Gag-Pol polyprotein | 2.7.7.49 | 0.463 | |
1xpc | AIT | Estrogen receptor | / | 0.463 | |
1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.463 | |
2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.463 | |
3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.463 | |
4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.463 | |
4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.463 | |
4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.463 | |
4ia2 | BIV | Vitamin D3 receptor A | / | 0.463 | |
4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.463 | |
4pkl | 1GH | Uncharacterized protein | / | 0.463 | |
1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
1thn | ADP | Anti-sigma F factor | / | 0.462 | |
2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.462 | |
4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.462 | |
4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.462 | |
1iyz | NDP | Probable quinone oxidoreductase | / | 0.461 | |
1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
1qzz | SAM | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.461 | |
1s9q | OHT | Estrogen-related receptor gamma | / | 0.461 | |
1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.461 | |
1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.461 | |
2fai | 459 | Estrogen receptor | / | 0.461 | |
2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.461 | |
2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.461 | |
2xiz | XIZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.461 | |
2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.461 | |
3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.461 | |
3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
3ngl | NAP | Bifunctional protein FolD | / | 0.461 | |
3rin | I2O | Mitogen-activated protein kinase 14 | / | 0.461 | |
4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.461 | |
4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.461 | |
4ivy | 1GT | Estrogen receptor | / | 0.461 | |
5dx3 | EST | Estrogen receptor | / | 0.461 | |
1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.460 | |
2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.460 | |
2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.460 | |
3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.460 | |
3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.460 | |
3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.460 | |
3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
3iw4 | LW4 | Protein kinase C alpha type | 2.7.11.13 | 0.460 | |
3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
3r0t | FU9 | Casein kinase II subunit alpha | 2.7.11.1 | 0.460 | |
4j26 | EST | Estrogen receptor beta | / | 0.460 | |
1dls | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.459 | |
1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.459 | |
1x7r | GEN | Estrogen receptor | / | 0.459 | |
2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
2bj4 | OHT | Estrogen receptor | / | 0.459 | |
2ejz | SAH | Diphthine synthase | / | 0.459 | |
2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.459 | |
3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.459 | |
3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
4azm | T4B | Fatty acid-binding protein, epidermal | / | 0.459 | |
4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.459 | |
4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.459 | |
4l8u | 9AZ | Serum albumin | / | 0.459 | |
5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.459 | |
1db5 | 6IN | Phospholipase A2, membrane associated | / | 0.458 | |
1ddu | CB3 | Thymidylate synthase | / | 0.458 | |
1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.458 | |
1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.458 | |
1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
1xuo | LA1 | Integrin alpha-L | / | 0.458 | |
1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.458 | |
2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.458 | |
2ow3 | BIM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.458 | |
2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
2xvw | 9NR | Serum albumin | / | 0.458 | |
3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.458 | |
3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.458 | |
3w5r | LOA | Vitamin D3 receptor | / | 0.458 | |
3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.458 | |
4ap1 | NAP | Steroid monooxygenase | / | 0.458 | |
4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.458 | |
4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.458 | |
4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.458 | |
4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.458 | |
4was | COO | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.458 | |
5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
5kf2 | COA | Predicted acetyltransferase | / | 0.458 | |
3eml | ZMA | Adenosine receptor A2a | / | 0.458 | |
1cqp | 803 | Integrin alpha-L | / | 0.457 | |
1dtn | APG | Mandelate racemase | / | 0.457 | |
1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
1rt5 | UC2 | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
1xp9 | AIJ | Estrogen receptor | / | 0.457 | |
2ham | C33 | Vitamin D3 receptor | / | 0.457 | |
2oax | SNL | Mineralocorticoid receptor | / | 0.457 | |
3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
3dol | GWI | Pol protein | / | 0.457 | |
3sr5 | Q12 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
1g4s | TPS | Thiamine-phosphate synthase | / | 0.456 | |
1kl2 | FON | Serine hydroxymethyltransferase | / | 0.456 | |
1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
1rkh | VD2 | Vitamin D3 receptor | / | 0.456 | |
1s19 | MC9 | Vitamin D3 receptor | / | 0.456 | |
1s1w | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.456 | |
1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.456 | |
2b1z | 17M | Estrogen receptor | / | 0.456 | |
2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.456 | |
2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.456 | |
2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.456 | |
2wcg | MT5 | Glucosylceramidase | 3.2.1.45 | 0.456 | |
3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
3fnu | 006 | HAP protein | / | 0.456 | |
3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.456 | |
3m7r | VDX | Vitamin D3 receptor | / | 0.456 | |
3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.456 | |
3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.456 | |
3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.456 | |
3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.456 | |
4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.456 | |
4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.456 | |
4lsl | 1YQ | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
4qi9 | MTX | Dihydrofolate reductase | / | 0.456 | |
5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
1ne4 | RP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.455 | |
1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
1sr7 | MOF | Progesterone receptor | / | 0.455 | |
1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.455 | |
1vrq | FON | Subunit alpha of sarocosine oxidase | / | 0.455 | |
1xdk | REA | Retinoic acid receptor beta | / | 0.455 | |
2bxm | IMN | Serum albumin | / | 0.455 | |
2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.455 | |
2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.455 | |
2jbl | SMA | Reaction center protein L chain | / | 0.455 | |
2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
2x21 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.455 | |
2yix | YIX | Mitogen-activated protein kinase 14 | / | 0.455 | |
2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.455 | |
3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.455 | |
3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.455 | |
3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.455 | |
3t9i | 3T9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
3vt9 | YI4 | Vitamin D3 receptor | / | 0.455 | |
3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
3zvu | A8S | Abscisic acid receptor PYR1 | / | 0.455 | |
4b1f | KRH | Glutamate racemase | / | 0.455 | |
4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.455 | |
4tyj | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.455 | |
4wbo | ANW | Rhodopsin kinase | / | 0.455 | |
4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.455 | |
1hnv | TBO | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
1l2j | ETC | Estrogen receptor beta | / | 0.454 | |
1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
2acw | UPG | Glycosyltransferase | / | 0.454 | |
2ywv | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | / | 0.454 | |
3a78 | 3EV | Vitamin D3 receptor | / | 0.454 | |
3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.454 | |
3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.454 | |
3htj | ET | EbrA repressor | / | 0.454 | |
3mee | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
3qts | X46 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.454 | |
3wiy | LC6 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.454 | |
4cuk | NAI | D-lactate dehydrogenase | / | 0.454 | |
3qak | UKA | Adenosine receptor A2a | / | 0.454 | |
1dna | CB3 | Thymidylate synthase | / | 0.453 | |
1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.453 | |
1ie9 | VDX | Vitamin D3 receptor | / | 0.453 | |
1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.453 | |
1jtq | LY3 | Thymidylate synthase | / | 0.453 | |
1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.453 | |
1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.453 | |
1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.453 | |
2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.453 | |
2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.453 | |
3dmj | GWE | Pol protein | / | 0.453 | |
3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.453 | |
3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.453 | |
3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.453 | |
3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.453 | |
4af3 | VX6 | Aurora kinase B | 2.7.11.1 | 0.453 | |
4dk5 | 0KO | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.453 | |
4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
4kko | 1RE | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
4l4x | NDP | AmphI | / | 0.453 | |
1e94 | ANP | ATP-dependent protease ATPase subunit HslU | / | 0.452 | |
1h9z | RWF | Serum albumin | / | 0.452 | |
1jtu | LYB | Thymidylate synthase | / | 0.452 | |
1kij | NOV | DNA gyrase subunit B | / | 0.452 | |
1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.452 | |
1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.452 | |
2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.452 | |
2fsz | OHT | Estrogen receptor beta | / | 0.452 | |
2jfz | 003 | Glutamate racemase | / | 0.452 | |
2lbd | REA | Retinoic acid receptor gamma | / | 0.452 | |
2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.452 | |
2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.452 | |
3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.452 | |
3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.452 | |
4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.452 | |
4gh3 | 0EV | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.452 | |
4ig3 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
4mbl | 26L | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.452 | |
1ckp | PVB | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.451 | |
1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.451 | |
1mjh | ATP | Universal stress protein MJ0577 | / | 0.451 | |
1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.451 | |
2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.451 | |
2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.451 | |
3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.451 | |
3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.451 | |
3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
3elm | 24F | Collagenase 3 | 3.4.24 | 0.451 | |
3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.451 | |
3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
3w0c | 6DS | Vitamin D3 receptor | / | 0.451 | |
4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.451 | |
4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.451 | |
5d7q | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.451 | |
1rt4 | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
2has | C3O | Vitamin D3 receptor | / | 0.450 | |
2osc | MUH | Angiopoietin-1 receptor | 2.7.10.1 | 0.450 | |
2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.450 | |
2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
3tm5 | SFG | Uncharacterized protein | / | 0.450 | |
3up3 | XCA | aceDAF-12 | / | 0.450 | |
3zhb | NAP | Putative dehydrogenase | / | 0.450 | |
4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.450 | |
4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.450 | |
4mv3 | ACP | Biotin carboxylase | 6.3.4.14 | 0.450 | |
4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
5i2f | BS5 | Histidine triad nucleotide-binding protein 1 | 3 | 0.450 | |
1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.449 | |
1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.449 | |
1lud | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
1syn | F89 | Thymidylate synthase | / | 0.449 | |
1tkx | GWB | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.449 | |
1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
1xiu | REA | Retinoic acid receptor RXR | / | 0.449 | |
1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.449 | |
2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
2c3o | TPP | Pyruvate synthase | / | 0.449 | |
2f8p | CEI | Obelin | / | 0.449 | |
2giu | FBR | Estrogen receptor beta | / | 0.449 | |
2hb7 | O1C | Vitamin D3 receptor | / | 0.449 | |
2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.449 | |
2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.449 | |
2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.449 | |
3k2h | LYA | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
3med | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
3vev | 0H4 | Glucokinase | 2.7.1.2 | 0.449 | |
4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.449 | |
4a95 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
4bw1 | S5B | Bromodomain-containing protein 4 | / | 0.449 | |
4eh6 | IRG | Mitogen-activated protein kinase 14 | / | 0.449 | |
4hfn | CIY | 2-alkenal reductase (NADP(+)-dependent) | / | 0.449 | |
4ia3 | BIV | Vitamin D3 receptor A | / | 0.449 | |
4ite | TEY | Vitamin D3 receptor | / | 0.449 | |
4ko0 | JLJ | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
4men | 25K | Bromodomain-containing protein 4 | / | 0.449 | |
4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.448 | |
1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
1txi | TX5 | Vitamin D3 receptor | / | 0.448 | |
1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 0.448 | |
2bns | MST | Reaction center protein L chain | / | 0.448 | |
2g44 | T3O | Estrogen receptor | / | 0.448 | |
2mm3 | CHO | Gastrotropin | / | 0.448 | |
2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.448 | |
2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.448 | |
2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.448 | |
3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.448 | |
3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.448 | |
3q2m | CKI | Spectinomycin phosphotransferase | / | 0.448 | |
3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.448 | |
3zei | AWH | O-acetylserine sulfhydrylase | / | 0.448 | |
4c9p | CAM | Cytochrome P450 | / | 0.448 | |
4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
4lr6 | 1XA | Bromodomain-containing protein 4 | / | 0.448 | |
4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.448 | |
4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 0.448 | |
1aiq | CB3 | Thymidylate synthase | / | 0.447 | |
1crb | RTL | Retinol-binding protein 1 | / | 0.447 | |
1db1 | VDX | Vitamin D3 receptor | / | 0.447 | |
1jut | LYD | Thymidylate synthase | / | 0.447 | |
1r6g | 442 | Thyroid hormone receptor beta | / | 0.447 | |
1tdu | CB3 | Thymidylate synthase | / | 0.447 | |
1w29 | TS0 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
2e20 | B4P | Propionate kinase | / | 0.447 | |
2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.447 | |
2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.447 | |
2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.447 | |
2xvv | 9DN | Serum albumin | / | 0.447 | |
2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
3ar6 | 12D | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.447 | |
3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.447 | |
3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.447 | |
3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.447 | |
3eta | 351 | Insulin receptor | 2.7.10.1 | 0.447 | |
3nhw | ZXZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.447 | |
3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
3qp8 | HL0 | Transcriptional activator, LuxR/UhpA family of regulators | / | 0.447 | |
3s41 | S41 | Glucokinase | 2.7.1.2 | 0.447 | |
3tm4 | SAM | Uncharacterized protein | / | 0.447 | |
4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
4ckc | SAH | mRNA-capping enzyme catalytic subunit | 2.1.1.56 | 0.447 | |
4dtk | 7LI | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
4gfg | 0XF | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.447 | |
4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.447 | |
4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.447 | |
4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
4yau | 2AM | NADPH--cytochrome P450 reductase | / | 0.447 | |
5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.447 | |
1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.446 | |
1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
1zpr | CB3 | Thymidylate synthase | / | 0.446 | |
2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
2hc4 | VDX | Vitamin D3 receptor A | / | 0.446 | |
2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.446 | |
3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.446 | |
3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.446 | |
3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.446 | |
3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.446 | |
3q95 | ESL | Estrogen receptor | / | 0.446 | |
3rth | RTH | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
3vrw | YS5 | Vitamin D3 receptor | / | 0.446 | |
3vt8 | YI3 | Vitamin D3 receptor | / | 0.446 | |
4ax8 | ADP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.446 | |
4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.446 | |
4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
4g1y | 0VO | Vitamin D3 receptor A | / | 0.446 | |
4g21 | 0VP | Vitamin D3 receptor A | / | 0.446 | |
4j0s | 1H3 | Bromodomain-containing protein 4 | / | 0.446 | |
4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.446 | |
4o4f | ATP | Kinase | / | 0.446 | |
4rup | H97 | Vitamin D3 receptor A | / | 0.446 | |
4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
5bsr | COA | 4-coumarate--CoA ligase 2 | 6.2.1.12 | 0.446 | |
5dxg | EST | Estrogen receptor | / | 0.446 | |
5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.446 | |
1axw | MTX | Thymidylate synthase | / | 0.445 | |
1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
1fd0 | 254 | Retinoic acid receptor gamma | / | 0.445 | |
1iiu | RTL | Retinol-binding protein 4 | / | 0.445 | |
1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.445 | |
1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
1rev | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.445 | |
1sqp | MYX | Cytochrome b | / | 0.445 | |
1txt | CAA | HMG-CoA synthase | / | 0.445 | |
2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.445 | |
2nv7 | 555 | Estrogen receptor beta | / | 0.445 | |
2opq | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
2q70 | DC8 | Estrogen receptor | / | 0.445 | |
2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.445 | |
3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.445 | |
3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.445 | |
3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.445 | |
3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.445 | |
4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
4gev | CB3 | Thymidylate synthase | / | 0.445 | |
4h1j | 0YH | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.445 | |
4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.445 | |
4lsj | LSJ | Glucocorticoid receptor | / | 0.445 | |
4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.445 | |
4zqc | F6F | Tryptophan synthase alpha chain | / | 0.445 | |
5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.445 | |
5c8a | 5AD | Probable transcriptional regulator | / | 0.445 | |
1err | RAL | Estrogen receptor | / | 0.444 | |
1fk9 | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
1jlq | SBN | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
1t0i | FMN | NAD(P)H-dependent FMN reductase LOT6 | / | 0.444 | |
1tdu | DUR | Thymidylate synthase | / | 0.444 | |
1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.444 | |
1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
2ati | IHU | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.444 | |
2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.444 | |
2ed3 | SAH | Diphthine synthase | / | 0.444 | |
2fdy | D4G | Cytochrome P450 2A6 | 1.14.13 | 0.444 | |
2p4i | MR9 | Angiopoietin-1 receptor | 2.7.10.1 | 0.444 | |
2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.444 | |
2vdv | SAM | tRNA (guanine-N(7)-)-methyltransferase | / | 0.444 | |
2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.444 | |
3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.444 | |
3fzt | 4JZ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.444 | |
3glm | COO | Glutaconyl-CoA decarboxylase alpha subunit | / | 0.444 | |
3iis | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.444 | |
3imx | B84 | Glucokinase | 2.7.1.2 | 0.444 | |
3iqe | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.444 | |
3l03 | 4OH | Estrogen receptor | / | 0.444 | |
3o6o | 94M | Heat shock protein 83 | / | 0.444 | |
3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.444 | |
4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
4aql | TXC | Guanine deaminase | 3.5.4.3 | 0.444 | |
4g20 | 484 | Vitamin D3 receptor A | / | 0.444 | |
4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
4i42 | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.444 | |
4j4v | SVR | Nucleocapsid protein | / | 0.444 | |
4lga | A2O | Abscisic acid receptor PYL2 | / | 0.444 | |
4pxm | EST | Estrogen receptor | / | 0.444 | |
4ruo | BIV | Vitamin D3 receptor A | / | 0.444 | |
4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.444 | |
4yek | THM | Thymidine phosphorylase | / | 0.444 | |
5kf2 | ACO | Predicted acetyltransferase | / | 0.444 | |
5k2c | ZMA | Adenosine receptor A2a | / | 0.444 | |
3uza | T4G | Adenosine receptor A2a | / | 0.444 | |
1ci7 | CB3 | Thymidylate synthase | 2.1.1.45 | 0.443 | |
1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.443 | |
1kt6 | RTL | Retinol-binding protein 4 | / | 0.443 | |
1l0l | FMX | Cytochrome b | / | 0.443 | |
1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
1x8l | OXR | Retinol dehydratase | / | 0.443 | |
1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
2a8s | GTP | U8 snoRNA-decapping enzyme | / | 0.443 | |
2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
2l98 | STL | Troponin C, slow skeletal and cardiac muscles | / | 0.443 | |
2qgt | EED | Estrogen receptor | / | 0.443 | |
2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.443 | |
2yat | EEU | Estrogen receptor | / | 0.443 | |
3c3e | FO1 | 2-phospho-L-lactate transferase | / | 0.443 | |
3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
3i0r | RT3 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
3nax | MP7 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.443 | |
3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.443 | |
4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.443 | |
4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.443 | |
4f1m | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.443 | |
4fsa | 0V3 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.443 | |
4h4m | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
4i41 | MIX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
4i5i | 4I5 | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.443 | |
4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.443 | |
4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.443 | |
4uyg | 73B | Bromodomain-containing protein 2 | / | 0.443 | |
5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.443 | |
1cqs | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.442 | |
1e3v | DXC | Steroid Delta-isomerase | 5.3.3.1 | 0.442 | |
1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.442 | |
1jx0 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.442 | |
1mc5 | AHE | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
1nc1 | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.442 | |
1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.442 | |
1rkg | VD1 | Vitamin D3 receptor | / | 0.442 | |
1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.442 | |
2bil | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
2gpv | OHT | Estrogen-related receptor gamma | / | 0.442 | |
2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.442 | |
3a8w | ATP | Protein kinase C iota type | 2.7.11.13 | 0.442 | |
3aqa | BYH | Bromodomain-containing protein 2 | / | 0.442 | |
3bej | MUF | Bile acid receptor | / | 0.442 | |
3h1j | SMA | Cytochrome b | / | 0.442 | |
3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.442 | |
3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.442 | |
3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.442 | |
3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
3p2o | NAD | Bifunctional protein FolD | / | 0.442 | |
3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
3pl8 | FAD | Pyranose 2-oxidase | / | 0.442 | |
3v49 | PK0 | Androgen receptor | / | 0.442 | |
3vqv | ANP | Pyrrolysine--tRNA ligase | / | 0.442 | |
3vrv | YSD | Vitamin D3 receptor | / | 0.442 | |
3w5p | 4OA | Vitamin D3 receptor | / | 0.442 | |
4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
4b8w | GDP | GDP-L-fucose synthase | 1.1.1.271 | 0.442 | |
4dca | ADP | Aminoglycoside phosphotransferase | / | 0.442 | |
4dm6 | TTB | Retinoic acid receptor beta | / | 0.442 | |
4fhh | 0U3 | Vitamin D3 receptor A | / | 0.442 | |
4j0r | 1H2 | Bromodomain-containing protein 4 | / | 0.442 | |
4jl6 | ADP | Adenylate kinase | / | 0.442 | |
4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.442 | |
4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.442 | |
5jtb | ZMA | Adenosine receptor A2a | / | 0.442 | |
3rey | XAC | Adenosine receptor A2a | / | 0.442 | |
1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.441 | |
1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.441 | |
1o5i | NAD | 3-oxoacyl-(Acyl carrier protein) reductase | / | 0.441 | |
1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.441 | |
1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
1yin | CM3 | Estrogen receptor | / | 0.441 | |
1zaf | 789 | Estrogen receptor beta | / | 0.441 | |
2cy2 | ACO | Probable acetyltransferase | / | 0.441 | |
2f2c | AP9 | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.441 | |
2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.441 | |
2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.441 | |
2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 | |
2puj | HPZ | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.441 | |
2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
2qcx | PF1 | Aminopyrimidine aminohydrolase | / | 0.441 | |
2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.441 | |
2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
2x1e | X1E | Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form | 2.3.1.164 | 0.441 | |
2xgs | 44P | Uncharacterized protein | / | 0.441 | |
2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
3dya | PZL | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
3ict | ADP | Coenzyme A disulfide reductase | / | 0.441 | |
3lla | ACP | Myosin heavy chain kinase A | 2.7.11.7 | 0.441 | |
3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
3rpr | 25Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
3s79 | ASD | Aromatase | 1.14.14.14 | 0.441 | |
3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
4bb2 | STR | Corticosteroid-binding globulin | / | 0.441 | |
4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
4fdp | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.441 | |
4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.441 | |
4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.440 | |
1jlc | FTC | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
1jxz | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.440 | |
1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.440 | |
1pz1 | NAP | General stress protein 69 | / | 0.440 | |
1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.440 | |
1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
2e1z | B4P | Propionate kinase | / | 0.440 | |
2kce | D16 | Thymidylate synthase | / | 0.440 | |
2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.440 | |
2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.440 | |
2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.440 | |
2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
3dlg | GWE | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
3gwl | FAD | FAD-linked sulfhydryl oxidase | 1.8.3.2 | 0.440 | |
3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.440 | |
3otq | MZL | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.440 | |
3qfv | NM7 | Serine/threonine-protein kinase MRCK beta | 2.7.11.1 | 0.440 | |
4a9i | P9I | Bromodomain-containing protein 2 | / | 0.440 | |
4at2 | ASD | Possible succinate dehydrogenase | / | 0.440 | |
4az0 | S61 | Lysosomal protective protein | 3.4.16.5 | 0.440 | |
4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.440 | |
4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.440 | |
4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.440 | |
4flp | JQ1 | Bromodomain testis-specific protein | / | 0.440 | |
4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
4i2p | G73 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 |