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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3tqbFOLDihydrofolate reductase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
3tqbFOLDihydrofolate reductase/1.000
3tq9MTXDihydrofolate reductase/0.769
1vj3TABDihydrofolate reductase1.5.1.30.648
1cd2FOLDihydrofolate reductase1.5.1.30.647
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.627
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.626
3fywXCFDihydrofolate reductase1.5.1.30.624
3jwcEKBDihydrofolate reductase/0.622
3dfrMTXDihydrofolate reductase1.5.1.30.618
3qly55VUncharacterized protein/0.614
4nx6FOLDihydrofolate reductase1.5.1.30.612
1rx3MTXDihydrofolate reductase1.5.1.30.609
4xe606UDihydrofolate reductase1.5.1.30.606
3cseN22Uncharacterized protein/0.605
7dfrFOLDihydrofolate reductase1.5.1.30.604
3frdDHFDihydrofolate reductase1.5.1.30.600
1dg7WRBDihydrofolate reductase1.5.1.30.598
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.595
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.595
3sa16DRDihydrofolate reductase/0.595
1df7MTXDihydrofolate reductase1.5.1.30.593
3qlzQLZUncharacterized protein/0.593
3fy9XCFDihydrofolate reductase1.5.1.30.592
1hfpMOTDihydrofolate reductase1.5.1.30.591
1ia1TQ3Dihydrofolate reductase1.5.1.30.590
3qls55VDihydrofolate reductase1.5.1.30.590
3td8D2RDihydrofolate reductase1.5.1.30.590
1jomFFODihydrofolate reductase1.5.1.30.589
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.588
1dg5TOPDihydrofolate reductase1.5.1.30.586
4ixeIXEDihydrofolate reductase1.5.1.30.585
2cd2FOLDihydrofolate reductase1.5.1.30.583
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.583
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.583
3jw5TOPDihydrofolate reductase/0.583
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.583
2w3vTOPDihydrofolate reductase/0.582
3ia4MTXDihydrofolate reductase/0.582
2fziDH3Dihydrofolate reductase1.5.1.30.581
2zzaFOLDihydrofolate reductase/0.579
3qlrQLRDihydrofolate reductase1.5.1.30.578
1m78CLZDihydrofolate reductase1.5.1.30.577
5cccDDFDihydrofolate reductase1.5.1.30.577
3frfXCFDihydrofolate reductase1.5.1.30.576
1dajMOTDihydrofolate reductase1.5.1.30.575
4ixgIXGDihydrofolate reductase1.5.1.30.574
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.573
1klkPMDDihydrofolate reductase1.5.1.30.572
3eek53SUncharacterized protein/0.572
1m7aMQUDihydrofolate reductase1.5.1.30.571
3datMTXDihydrofolate reductase/0.571
4m2xTMQDihydrofolate reductase1.5.1.30.571
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.570
3srwQ27Dihydrofolate reductase1.5.1.30.570
3cd2MTXDihydrofolate reductase1.5.1.30.569
4ixfIXFDihydrofolate reductase1.5.1.30.569
1ddsMTXDihydrofolate reductase1.5.1.30.568
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.568
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.568
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.567
2cig1DGDihydrofolate reductase1.5.1.30.567
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.567
4fgh0U6Dihydrofolate reductase1.5.1.30.567
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.566
4x5fFOLDihydrofolate reductase1.5.1.30.566
2fzhDH1Dihydrofolate reductase1.5.1.30.565
3fraI2HDihydrofolate reductase1.5.1.30.565
4x5gFOLDihydrofolate reductase1.5.1.30.565
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.564
4p66MTXDihydrofolate reductase/0.564
1aoeGW3Dihydrofolate reductase1.5.1.30.563
2qk8MTXDihydrofolate reductase/0.563
4kjjFOLDihydrofolate reductase1.5.1.30.563
4nx7FOLDihydrofolate reductase1.5.1.30.563
1e26GPBDihydrofolate reductase1.5.1.30.561
3drcMTXDihydrofolate reductase1.5.1.30.561
3eem53VUncharacterized protein/0.561
3fyvXCFDihydrofolate reductase1.5.1.30.561
3jwm5WBDihydrofolate reductase/0.561
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.561
1ly4COQDihydrofolate reductase1.5.1.30.560
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.560
4elb34SDihydrofolate reductase/0.560
1hfqMOTDihydrofolate reductase1.5.1.30.559
2w9gTOPDihydrofolate reductase1.5.1.30.557
1draMTXDihydrofolate reductase1.5.1.30.556
3eej53RUncharacterized protein/0.556
3freTOPDihydrofolate reductase1.5.1.30.556
4h9753SDihydrofolate reductase1.5.1.30.556
1m79MQ1Dihydrofolate reductase1.5.1.30.555
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.554
3gi2GHWDihydrofolate reductase1.5.1.30.554
3r336MEDihydrofolate reductase1.5.1.30.554
1rb3MTXDihydrofolate reductase1.5.1.30.553
3srrQ20Dihydrofolate reductase1.5.1.30.553
4m6l21VDihydrofolate reductase1.5.1.30.553
1rf7DHFDihydrofolate reductase1.5.1.30.552
3qlxQLRUncharacterized protein/0.551
1drbMTXDihydrofolate reductase1.5.1.30.550
1tdrMTXDihydrofolate reductase1.5.1.30.550
1ia2TQ4Dihydrofolate reductase1.5.1.30.549
2drcMTXDihydrofolate reductase1.5.1.30.549
3dg8RJ6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.549
3qyoQ24Dihydrofolate reductase1.5.1.30.549
4h9506UDihydrofolate reductase1.5.1.30.548
4fgg0U5Dihydrofolate reductase1.5.1.30.547
3sai9DRDihydrofolate reductase/0.546
1ia3TQ5Dihydrofolate reductase1.5.1.30.545
1rc4DDFDihydrofolate reductase1.5.1.30.544
1s3yTQTDihydrofolate reductase1.5.1.30.544
3dauMTXDihydrofolate reductase1.5.1.30.543
3qlwN22Dihydrofolate reductase1.5.1.30.542
1ly3COGDihydrofolate reductase1.5.1.30.540
3fy8XCFDihydrofolate reductase1.5.1.30.540
3sh25DRDihydrofolate reductase1.5.1.30.538
4kebFOLDihydrofolate reductase1.5.1.30.538
3d80Q22Dihydrofolate reductase1.5.1.30.536
3eel53TUncharacterized protein/0.536
3m08RARDihydrofolate reductase1.5.1.30.536
3sa27DRDihydrofolate reductase/0.536
4ele31IDihydrofolate reductase/0.536
1re7FOLDihydrofolate reductase1.5.1.30.535
3srqQ19Dihydrofolate reductase1.5.1.30.535
3sruQ26Dihydrofolate reductase1.5.1.30.535
3ix9MTXDihydrofolate reductase1.5.1.30.534
3l3rOAGDihydrofolate reductase1.5.1.30.534
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.532
1ia4TQ6Dihydrofolate reductase1.5.1.30.531
1ohkCOPDihydrofolate reductase1.5.1.30.531
4m7vRARDihydrofolate reductase/0.528
1u72MTXDihydrofolate reductase1.5.1.30.527
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.527
4elb34RDihydrofolate reductase/0.527
1ddrMTXDihydrofolate reductase1.5.1.30.526
3eigMTXDihydrofolate reductase1.5.1.30.526
3srsM23Dihydrofolate reductase1.5.1.30.524
1disBDMDihydrofolate reductase1.5.1.30.523
1jolFFODihydrofolate reductase1.5.1.30.523
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.523
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.522
4elh53IDihydrofolate reductase/0.522
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.521
3och2MXDihydrofolate reductase1.5.1.30.521
3qlsNDPDihydrofolate reductase1.5.1.30.521
1rg7MTXDihydrofolate reductase1.5.1.30.520
4cd2FOLDihydrofolate reductase1.5.1.30.520
1hfrMOTDihydrofolate reductase1.5.1.30.518
3ql3FOLDihydrofolate reductase1.5.1.30.518
1kmsLIHDihydrofolate reductase1.5.1.30.515
3i8aN22Dihydrofolate reductase1.5.1.30.515
5eccNAPDehydrofolate reductase type I/0.515
3k47D09Dihydrofolate reductase1.5.1.30.514
3ghwGHWDihydrofolate reductase1.5.1.30.513
3lfcZ86Mitogen-activated protein kinase 14/0.513
4elf35IDihydrofolate reductase/0.513
4kfjFOLDihydrofolate reductase1.5.1.30.513
3ntz3TZDihydrofolate reductase1.5.1.30.512
2fzjDH3Dihydrofolate reductase1.5.1.30.511
3l8sBFFMitogen-activated protein kinase 14/0.511
4dphP65Bifunctional dihydrofolate reductase-thymidylate synthase/0.511
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.511
4g8zTOPDihydrofolate reductase1.5.1.30.511
1bozPRDDihydrofolate reductase1.5.1.30.510
4i1nFOLDihydrofolate reductase1.5.1.30.510
4kbn25UDihydrofolate reductase1.5.1.30.510
1uhlMEIRetinoic acid receptor RXR-beta/0.509
3gyf51PDihydrofolate reductase1.5.1.30.508
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.508
1kmvLIIDihydrofolate reductase1.5.1.30.505
3fl9TOPDihydrofolate reductase/0.505
3oafOAGDihydrofolate reductase1.5.1.30.504
3uvvREARetinoic acid receptor RXR-alpha/0.504
4ddrMMVDihydrofolate reductase1.5.1.30.504
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.503
3sgy06WDihydrofolate reductase1.5.1.30.503
4x5jFOLDihydrofolate reductase1.5.1.30.503
1kceCB3Thymidylate synthase/0.502
3d84NDPDihydrofolate reductase1.5.1.30.502
4hni16WCasein kinase I isoform epsilon2.7.11.10.502
1rx2FOLDihydrofolate reductase1.5.1.30.501
1bzfTMQDihydrofolate reductase1.5.1.30.500
1dyjDDFDihydrofolate reductase1.5.1.30.500
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.500
4iv21GREstrogen receptor/0.500
5hi6MTXDihydrofolate reductase/0.500
1uydPU8Heat shock protein HSP 90-alpha/0.499
3fl8RARDihydrofolate reductase/0.499
3tq8TOPDihydrofolate reductase/0.499
4g95OAGDihydrofolate reductase1.5.1.30.499
1rx1NAPDihydrofolate reductase1.5.1.30.498
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.498
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.498
1olmVTQSEC14-like protein 2/0.496
3gc9B45Mitogen-activated protein kinase 112.7.11.240.496
2ji9ADPOxalyl-CoA decarboxylase4.1.1.80.493
3ghvGHCDihydrofolate reductase1.5.1.30.493
3rg9WRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.493
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.493
2tscCB3Thymidylate synthase/0.492
1pkfEPDEpothilone C/D epoxidase1.140.491
2p15EZTEstrogen receptor/0.491
4j6dTESCytochrome P450 monooxygenase/0.491
4kd79DRDihydrofolate reductase1.5.1.30.491
2hm9TRRDihydrofolate reductase1.5.1.30.490
3njoPYVAbscisic acid receptor PYR1/0.490
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.490
4twpAXITyrosine-protein kinase ABL12.7.10.20.490
5d7pAR6NAD-dependent protein deacetylase sirtuin-23.5.10.490
4o71CPBBromodomain-containing protein 4/0.489
3ds6A17Mitogen-activated protein kinase 14/0.488
3g8dADPBiotin carboxylase6.3.4.140.488
3m09RARDihydrofolate reductase1.5.1.30.488
5cc9DDFDihydrofolate reductase1.5.1.30.488
4j6cSTRCytochrome P450 monooxygenase/0.487
1diuBDMDihydrofolate reductase1.5.1.30.485
3gwfNAPCyclohexanone monooxygenase/0.485
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.483
1uyfPU1Heat shock protein HSP 90-alpha/0.483
3tdaPN0Cytochrome P450 2D6/0.483
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.483
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.483
4kne1CYDihydrofolate reductase1.5.1.30.483
4l9q9TPSerum albumin/0.483
1n4hREANuclear receptor ROR-beta/0.482
1ohjCOPDihydrofolate reductase1.5.1.30.482
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.482
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.482
1nq7ARLNuclear receptor ROR-beta/0.481
1og5SWFCytochrome P450 2C9/0.481
3sqyQ11Dihydrofolate reductase1.5.1.30.481
4ia1BIVVitamin D3 receptor A/0.481
4nh82LCHeat shock protein HSP 90-alpha/0.481
1rd4L08Integrin alpha-L/0.480
1s3wTQTDihydrofolate reductase1.5.1.30.480
2w3wVG9Dihydrofolate reductase/0.480
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
2z3uCRRCytochrome P450/0.479
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.479
3s7a684Dihydrofolate reductase1.5.1.30.479
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.479
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.479
4kak06UDihydrofolate reductase1.5.1.30.479
1uyePU9Heat shock protein HSP 90-alpha/0.478
2qe4JJ3Estrogen receptor/0.478
3a1l2CCCytochrome P450/0.478
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.478
3nj0PYVAbscisic acid receptor PYL2/0.478
3qm4PN0Cytochrome P450 2D6/0.478
4iw8KN3Estrogen receptor/0.478
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.478
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.478
4p68MTXDihydrofolate reductase/0.478
4x5iFOLDihydrofolate reductase1.5.1.30.478
2w3mFOLDihydrofolate reductase1.5.1.30.477
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.477
5bp9SAHPutative methyltransferase protein/0.477
2bbqPFGThymidylate synthase/0.476
4gkt0O1Queuine tRNA-ribosyltransferase2.4.2.290.476
1x2hLPALipoate-protein ligase A6.3.1.200.475
2x20PIDPeridinin-chlorophyll a-binding protein 1, chloroplastic/0.475
2yee2ECHeat shock protein HSP 90-alpha/0.475
3nxoD2BDihydrofolate reductase1.5.1.30.475
3p9tTCLRepressor/0.475
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.475
4iui1GQEstrogen receptor/0.475
4p6wMOFGlucocorticoid receptor/0.475
1qxlFR8Adenosine deaminase3.5.4.40.474
2bf7HBIPteridine reductase 11.5.1.330.474
2d0kFOLDihydrofolate reductase1.5.1.30.474
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.474
4j7uYTZSepiapterin reductase1.1.1.1530.474
1kzjCB3Thymidylate synthase/0.473
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.473
1rdtL79Retinoic acid receptor RXR-alpha/0.473
2bakAQZMitogen-activated protein kinase 14/0.473
3d77NBBPheromone-binding protein ASP1/0.473
3dhoB2MStreptogramin A acetyltransferase2.3.10.473
4a9yAQZMitogen-activated protein kinase 14/0.473
4fhbFOLDihydrofolate reductase1.5.1.30.473
4j7xSASSepiapterin reductase1.1.1.1530.473
1dyrTOPDihydrofolate reductase1.5.1.30.472
1l2iETCEstrogen receptor/0.472
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.472
3nxrD2DDihydrofolate reductase1.5.1.30.472
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.471
1fmjRTLRetinol dehydratase/0.471
1tl1H18Gag-Pol polyprotein2.7.7.490.471
2agvTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.471
2gq3COAMalate synthase G/0.471
2ittAEEEpidermal growth factor receptor2.7.10.10.471
2yjxYJXHeat shock protein HSP 90-alpha/0.471
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.471
3gieACPSensor histidine kinase DesK2.7.13.30.471
3ibqATPPyridoxal kinase/0.471
3nu03TUDihydrofolate reductase1.5.1.30.471
3v1mHPK2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.471
4bfrJ82Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform2.7.1.1530.471
4dhyS41Glucokinase2.7.1.20.471
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.470
1r2jFADFkbI/0.470
1tl3H20Gag-Pol polyprotein2.7.7.490.470
1xlsREARetinoic acid receptor RXR-alpha/0.470
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.470
3lakKR1Gag-Pol polyprotein2.7.7.490.470
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
3vf60H6Glucokinase2.7.1.20.470
4l4cCAMCamphor 5-monooxygenase1.14.15.10.470
4m6kFOLDihydrofolate reductase1.5.1.30.470
4o95245Cytokinin dehydrogenase 4/0.470
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.470
1bucFADAcyl-CoA dehydrogenase, short-chain specific1.3.8.10.469
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
1tktH12Gag-Pol polyprotein2.7.7.490.469
1ywrLI9Mitogen-activated protein kinase 14/0.469
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.469
2p1v5TNRetinoic acid receptor RXR-alpha/0.469
3e5aVX6Aurora kinase A2.7.11.10.469
3nxyD2HDihydrofolate reductase1.5.1.30.469
4ia7BIVVitamin D3 receptor A/0.469
4kfj1R0Dihydrofolate reductase1.5.1.30.469
5bt42LOBromodomain-containing protein 4/0.469
1rx7FOLDihydrofolate reductase1.5.1.30.468
3new3NEMitogen-activated protein kinase 14/0.468
3njoP2MAbscisic acid receptor PYR1/0.468
4nb6444Nuclear receptor ROR-gamma/0.468
5jadFB2Platelet-activating factor acetylhydrolase3.1.1.470.468
1dr2TAPDihydrofolate reductase1.5.1.30.467
1k749CRRetinoic acid receptor RXR-alpha/0.467
1xduSFGAclacinomycin 10-hydroxylase RdmB4.1.10.467
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.467
3vt7VDXVitamin D3 receptor/0.467
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
1ai9NDPDihydrofolate reductase1.5.1.30.466
1ju6LYAThymidylate synthase2.1.1.450.466
1m78NDPDihydrofolate reductase1.5.1.30.466
1n71COAAac(6')-Ii protein/0.466
1o5rFR9Adenosine deaminase3.5.4.40.466
1tkzH16Gag-Pol polyprotein2.7.7.490.466
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.466
2hb8MVDVitamin D3 receptor/0.466
2hw2RFPRifampin ADP-ribosyl transferase/0.466
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.466
3l0lHC3Nuclear receptor ROR-gamma/0.466
4lt63ATPoly(A) polymerase gamma2.7.7.190.466
1dreMTXDihydrofolate reductase1.5.1.30.465
1fmlRTLRetinol dehydratase/0.465
1pd8CO4Dihydrofolate reductase1.5.1.30.465
1t47NTD4-hydroxyphenylpyruvate dioxygenase1.13.11.270.465
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.465
2fmn4HF5,10-methylenetetrahydrofolate reductase1.5.1.200.465
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.465
2q7gCCLPyrrolysine--tRNA ligase/0.465
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.465
2w0hNDPTrypanothione reductase/0.465
2wo7ASVIsopenicillin N synthase1.21.3.10.465
2x7hPFNProstaglandin reductase 310.465
3fsuC2F5,10-methylenetetrahydrofolate reductase1.5.1.200.465
3nxtD2EDihydrofolate reductase1.5.1.30.465
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.465
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.465
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.465
4i9i1DYTankyrase-12.4.2.300.465
1blzACVIsopenicillin N synthase1.21.3.10.464
1dhfFOLDihydrofolate reductase1.5.1.30.464
1dkfBMSRetinoic acid receptor alpha/0.464
1dr3TAPDihydrofolate reductase1.5.1.30.464
1ove358Mitogen-activated protein kinase 14/0.464
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.464
2p1u4TNRetinoic acid receptor RXR-alpha/0.464
2vg7NNIGag-Pol polyprotein2.7.7.490.464
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.464
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.464
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.464
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.464
3rl35GPMetallophosphoesterase MPPED23.10.464
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.464
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
4k9yK9YFocal adhesion kinase 12.7.10.20.464
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.463
1nceCB3Thymidylate synthase/0.463
1rh3MTXDihydrofolate reductase1.5.1.30.463
1rt7UC4Gag-Pol polyprotein2.7.7.490.463
1xpcAITEstrogen receptor/0.463
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.463
2ban357Gag-Pol polyprotein2.7.7.490.463
2ykcYKCHeat shock protein HSP 90-alpha/0.463
3dg8NDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.463
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.463
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.463
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.463
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.463
4ia2BIVVitamin D3 receptor A/0.463
4j6bPLOCytochrome P450 monooxygenase/0.463
4pkl1GHUncharacterized protein/0.463
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
1rf9DBRCamphor 5-monooxygenase1.14.15.10.462
1thnADPAnti-sigma F factor/0.462
2wi72KLHeat shock protein HSP 90-alpha/0.462
4o761M3Bromodomain-containing protein 4/0.462
4qa0SHHHistone deacetylase 83.5.1.980.462
1iyzNDPProbable quinone oxidoreductase/0.461
1mvsDTMDihydrofolate reductase1.5.1.30.461
1qzzSAMAclacinomycin 10-hydroxylase RdmB4.1.10.461
1s9qOHTEstrogen-related receptor gamma/0.461
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.461
1uy7PU4Heat shock protein HSP 90-alpha/0.461
2fai459Estrogen receptor/0.461
2qd5CHDFerrochelatase, mitochondrial4.99.1.10.461
2w6qOA5Biotin carboxylase6.3.4.140.461
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.461
2z97CAMCamphor 5-monooxygenase1.14.15.10.461
2zb45OPProstaglandin reductase 21.3.1.480.461
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.461
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
3nglNAPBifunctional protein FolD/0.461
3rinI2OMitogen-activated protein kinase 14/0.461
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.461
4dscA8SAbscisic acid receptor PYL3/0.461
4ivy1GTEstrogen receptor/0.461
5dx3ESTEstrogen receptor/0.461
1mvcBM6Retinoic acid receptor RXR-alpha/0.460
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.460
2h55DZ8Heat shock protein HSP 90-alpha/0.460
2w6oOA3Biotin carboxylase6.3.4.140.460
3gcq1BUMitogen-activated protein kinase 14/0.460
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.460
3hz142CHeat shock protein HSP 90-alpha/0.460
3is9AC7Gag-Pol polyprotein2.7.7.490.460
3iw4LW4Protein kinase C alpha type2.7.11.130.460
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
3r0tFU9Casein kinase II subunit alpha2.7.11.10.460
4j26ESTEstrogen receptor beta/0.460
1dlsMTXDihydrofolate reductase1.5.1.30.459
1fbyREARetinoic acid receptor RXR-alpha/0.459
1q5dEPBEpothilone C/D epoxidase1.140.459
1x7rGENEstrogen receptor/0.459
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
2bj4OHTEstrogen receptor/0.459
2ejzSAHDiphthine synthase/0.459
2vcmM11Isopenicillin N synthase1.21.3.10.459
2ykbYKBHeat shock protein HSP 90-alpha/0.459
3h3t16HCollagen type IV alpha-3-binding protein/0.459
3s3vTOPDihydrofolate reductase1.5.1.30.459
4azmT4BFatty acid-binding protein, epidermal/0.459
4bfpSWYTankyrase-22.4.2.300.459
4ead0NPThymidine phosphorylase2.4.2.40.459
4l8u9AZSerum albumin/0.459
5ab6CAANonspecific lipid-transfer protein, putative/0.459
1db56INPhospholipase A2, membrane associated/0.458
1dduCB3Thymidylate synthase/0.458
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.458
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.458
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
1xuoLA1Integrin alpha-L/0.458
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.458
2ociTYCValacyclovir hydrolase3.10.458
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.458
2w3aTOPDihydrofolate reductase1.5.1.30.458
2xvw9NRSerum albumin/0.458
3cz09ODPheromone-binding protein ASP1/0.458
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.458
3h4vNAPPteridine reductase 11.5.1.330.458
3w5rLOAVitamin D3 receptor/0.458
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.458
4ap1NAPSteroid monooxygenase/0.458
4i8vBHFCytochrome P450 1A11.14.14.10.458
4jbtASDCytochrome P450 monooxygenase/0.458
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.458
4pnmNU1Tankyrase-22.4.2.300.458
4wasCOOEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.458
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
5kf2COAPredicted acetyltransferase/0.458
3emlZMAAdenosine receptor A2a/0.458
1cqp803Integrin alpha-L/0.457
1dtnAPGMandelate racemase/0.457
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
1rt5UC2Gag-Pol polyprotein2.7.7.490.457
1xp9AIJEstrogen receptor/0.457
2hamC33Vitamin D3 receptor/0.457
2oaxSNLMineralocorticoid receptor/0.457
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.457
3dolGWIPol protein/0.457
3sr5Q12Dihydrofolate reductase1.5.1.30.457
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
1g4sTPSThiamine-phosphate synthase/0.456
1kl2FONSerine hydroxymethyltransferase/0.456
1rb2FOLDihydrofolate reductase1.5.1.30.456
1rkhVD2Vitamin D3 receptor/0.456
1s19MC9Vitamin D3 receptor/0.456
1s1wUC1Gag-Pol polyprotein2.7.7.490.456
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.456
1yqj6NPMitogen-activated protein kinase 14/0.456
2b1z17MEstrogen receptor/0.456
2obxINI6,7-dimethyl-8-ribityllumazine synthase 22.5.1.780.456
2pmdGNPTranslation initiation factor 2 subunit gamma/0.456
2pulACPMethylthioribose kinase2.7.1.1000.456
2wcgMT5Glucosylceramidase3.2.1.450.456
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.456
3fnu006HAP protein/0.456
3koo24DBifunctional epoxide hydrolase 23.3.2.100.456
3m7rVDXVitamin D3 receptor/0.456
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.456
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.456
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.456
3ua506XCytochrome P450 2B61.14.130.456
4eevL1XHepatocyte growth factor receptor2.7.10.10.456
4li61XOTankyrase-12.4.2.300.456
4lsl1YQGag-Pol polyprotein2.7.7.490.456
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.456
4qi9MTXDihydrofolate reductase/0.456
5cp4CAMCamphor 5-monooxygenase1.14.15.10.456
1ne4RP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.455
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
1rx5DDFDihydrofolate reductase1.5.1.30.455
1sr7MOFProgesterone receptor/0.455
1uy9PU6Heat shock protein HSP 90-alpha/0.455
1vrqFONSubunit alpha of sarocosine oxidase/0.455
1xdkREARetinoic acid receptor beta/0.455
2bxmIMNSerum albumin/0.455
2d29FADAcyl-CoA dehydrogenase/0.455
2i0ePDSProtein kinase C beta type2.7.11.130.455
2jblSMAReaction center protein L chain/0.455
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
2x21PIDPeridinin-chlorophyll a-binding protein 1, chloroplastic/0.455
2yixYIXMitogen-activated protein kinase 14/0.455
2ykiYKIHeat shock protein HSP 90-alpha/0.455
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.455
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.455
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.455
3t9i3T9Serine/threonine-protein kinase pim-12.7.11.10.455
3vt9YI4Vitamin D3 receptor/0.455
3zoiM2WIsopenicillin N synthase1.21.3.10.455
3zvuA8SAbscisic acid receptor PYR1/0.455
4b1fKRHGlutamate racemase/0.455
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.455
4tyj0LIFibroblast growth factor receptor 42.7.10.10.455
4wboANWRhodopsin kinase/0.455
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.455
1hnvTBOGag-Pol polyprotein2.7.7.490.454
1l2jETCEstrogen receptor beta/0.454
1rx8FOLDihydrofolate reductase1.5.1.30.454
2acwUPGGlycosyltransferase/0.454
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.454
3a783EVVitamin D3 receptor/0.454
3d78NBBPheromone-binding protein ASP1/0.454
3fkoFKOMitogen-activated protein kinase 14/0.454
3htjETEbrA repressor/0.454
3meeT27Gag-Pol polyprotein2.7.7.490.454
3qtsX46Cyclin-dependent kinase 22.7.11.220.454
3r6pA8SAbscisic acid receptor PYL10/0.454
3wiyLC6Induced myeloid leukemia cell differentiation protein Mcl-1/0.454
4cukNAID-lactate dehydrogenase/0.454
3qakUKAAdenosine receptor A2a/0.454
1dnaCB3Thymidylate synthase/0.453
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.453
1ie9VDXVitamin D3 receptor/0.453
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.453
1jtqLY3Thymidylate synthase/0.453
1m13HYFNuclear receptor subfamily 1 group I member 2/0.453
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.453
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.453
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
2a19ANPInterferon-induced, double-stranded RNA-activated protein kinase2.7.11.10.453
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.453
2ewaSB2Mitogen-activated protein kinase 14/0.453
2xkfBX1Serine/threonine-protein kinase Nek22.7.11.10.453
3dmjGWEPol protein/0.453
3fwjCAMCamphor 5-monooxygenase1.14.15.10.453
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.453
3hv3R49Mitogen-activated protein kinase 14/0.453
3hz137DHeat shock protein HSP 90-alpha/0.453
3lalKRVGag-Pol polyprotein2.7.7.490.453
3n0hTOPDihydrofolate reductase1.5.1.30.453
3oapREARetinoic acid receptor RXR-alpha/0.453
4af3VX6Aurora kinase B2.7.11.10.453
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4dpy2P0Mevalonate diphosphate decarboxylase/0.453
4jx1CAHCamphor 5-monooxygenase1.14.15.10.453
4kko1REGag-Pol polyprotein2.7.7.490.453
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.453
4l4xNDPAmphI/0.453
1e94ANPATP-dependent protease ATPase subunit HslU/0.452
1h9zRWFSerum albumin/0.452
1jtuLYBThymidylate synthase/0.452
1kijNOVDNA gyrase subunit B/0.452
1r00SAHAclacinomycin 10-hydroxylase RdmB4.1.10.452
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.452
2ea1GPGRibonuclease I3.1.27.60.452
2fszOHTEstrogen receptor beta/0.452
2jfz003Glutamate racemase/0.452
2lbdREARetinoic acid receptor gamma/0.452
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.452
2vr1ATFBiotin carboxylase6.3.4.140.452
3d0bSNXHeat shock protein HSP 90-alpha/0.452
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.452
4a81DXCMajor pollen allergen Bet v 1-A/0.452
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
4e5yNDPGDP-L-fucose synthase1.1.1.2710.452
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.290.452
4ig3T27Gag-Pol polyprotein2.7.7.490.452
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.452
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.452
1ckpPVBCyclin-dependent kinase 22.7.11.220.451
1dliUDXUDP-glucose 6-dehydrogenase/0.451
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.451
1mjhATPUniversal stress protein MJ0577/0.451
1ml6GBXGlutathione S-transferase A22.5.1.180.451
2aclREARetinoic acid receptor RXR-alpha/0.451
2hqpNDPDihydrofolate reductase1.5.1.30.451
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.451
3ar7TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.451
3cqeP91Wee1-like protein kinase2.7.10.20.451
3ctj320Hepatocyte growth factor receptor2.7.10.10.451
3elm24FCollagenase 33.4.240.451
3qdd94MHeat shock protein HSP 90-alpha/0.451
3qlhT27Gag-Pol polyprotein2.7.7.490.451
3w0c6DSVitamin D3 receptor/0.451
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.451
4qa2SHHHistone deacetylase 83.5.1.980.451
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.451
5d7qAR6NAD-dependent protein deacetylase sirtuin-23.5.10.451
1rt4UC1Gag-Pol polyprotein2.7.7.490.450
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2hasC3OVitamin D3 receptor/0.450
2oscMUHAngiopoietin-1 receptor2.7.10.10.450
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.450
2zd1T27Gag-Pol polyprotein2.7.7.490.450
3nxvD2FDihydrofolate reductase1.5.1.30.450
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.450
3tm5SFGUncharacterized protein/0.450
3up3XCAaceDAF-12/0.450
3zhbNAPPutative dehydrogenase/0.450
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4iyg1HUStrictosidine synthase4.3.3.20.450
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.450
4mv3ACPBiotin carboxylase6.3.4.140.450
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.450
5i2fBS5Histidine triad nucleotide-binding protein 130.450
1gj5130Prothrombin3.4.21.50.449
1h35R01Squalene--hopene cyclase4.2.1.1290.449
1ludTRRDihydrofolate reductase1.5.1.30.449
1synF89Thymidylate synthase/0.449
1tkxGWBGag-Pol polyprotein2.7.7.490.449
1umlFR4Adenosine deaminase3.5.4.40.449
1vyrFMNPentaerythritol tetranitrate reductase/0.449
1xiuREARetinoic acid receptor RXR/0.449
1zzlTZYMitogen-activated protein kinase 14/0.449
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.449
2c3oTPPPyruvate synthase/0.449
2f8pCEIObelin/0.449
2giuFBREstrogen receptor beta/0.449
2hb7O1CVitamin D3 receptor/0.449
2hk9NAPShikimate dehydrogenase (NADP(+))/0.449
2jedLG8Protein kinase C theta type2.7.11.130.449
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.449
2zcePYLPyrrolysine--tRNA ligase/0.449
3k2hLYABifunctional dihydrofolate reductase-thymidylate synthase/0.449
3med65BGag-Pol polyprotein2.7.7.490.449
3vev0H4Glucokinase2.7.1.20.449
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.449
4a95NHWGlycylpeptide N-tetradecanoyltransferase/0.449
4bw1S5BBromodomain-containing protein 4/0.449
4eh6IRGMitogen-activated protein kinase 14/0.449
4hfnCIY2-alkenal reductase (NADP(+)-dependent)/0.449
4ia3BIVVitamin D3 receptor A/0.449
4iteTEYVitamin D3 receptor/0.449
4ko0JLJGag-Pol polyprotein2.7.7.490.449
4men25KBromodomain-containing protein 4/0.449
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
1dljUGAUDP-glucose 6-dehydrogenase/0.448
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.448
1txiTX5Vitamin D3 receptor/0.448
1zw9H64ATP-dependent molecular chaperone HSP82/0.448
2bnsMSTReaction center protein L chain/0.448
2g44T3OEstrogen receptor/0.448
2mm3CHOGastrotropin/0.448
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.448
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.448
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
2znpK55Peroxisome proliferator-activated receptor delta/0.448
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.448
3h3r14HCollagen type IV alpha-3-binding protein/0.448
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.448
3q2mCKISpectinomycin phosphotransferase/0.448
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.448
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.448
3zeiAWHO-acetylserine sulfhydrylase/0.448
4c9pCAMCytochrome P450/0.448
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4lr61XABromodomain-containing protein 4/0.448
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4tjy3GNTankyrase-22.4.2.300.448
4z1fH71Heat shock protein 75 kDa, mitochondrial/0.448
1aiqCB3Thymidylate synthase/0.447
1crbRTLRetinol-binding protein 1/0.447
1db1VDXVitamin D3 receptor/0.447
1jutLYDThymidylate synthase/0.447
1r6g442Thyroid hormone receptor beta/0.447
1tduCB3Thymidylate synthase/0.447
1w29TS06,7-dimethyl-8-ribityllumazine synthase2.5.1.780.447
2e20B4PPropionate kinase/0.447
2jibADPOxalyl-CoA decarboxylase4.1.1.80.447
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.447
2o7pNAPRiboflavin biosynthesis protein RibD/0.447
2puiADPMethylthioribose kinase2.7.1.1000.447
2xvv9DNSerum albumin/0.447
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
3ar612DSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.447
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.447
3c1xCKKHepatocyte growth factor receptor2.7.10.10.447
3cyz9ODPheromone-binding protein ASP1/0.447
3eta351Insulin receptor2.7.10.10.447
3nhwZXZRibosyldihydronicotinamide dehydrogenase [quinone]/0.447
3o0iP54Heat shock protein HSP 90-alpha/0.447
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
3p6nDSOCamphor 5-monooxygenase1.14.15.10.447
3qp8HL0Transcriptional activator, LuxR/UhpA family of regulators/0.447
3s41S41Glucokinase2.7.1.20.447
3tm4SAMUncharacterized protein/0.447
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4ckcSAHmRNA-capping enzyme catalytic subunit2.1.1.560.447
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.447
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.447
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.447
4h380YXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.447
4iwv1J9Glucokinase2.7.1.20.447
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.447
4yau2AMNADPH--cytochrome P450 reductase/0.447
5ab7MLCNonspecific lipid-transfer protein, putative/0.447
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.446
1uyuCAMCamphor 5-monooxygenase1.14.15.10.446
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
1yhoTRRDihydrofolate reductase1.5.1.30.446
1zprCB3Thymidylate synthase/0.446
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
2hc4VDXVitamin D3 receptor A/0.446
2w6mOA1Biotin carboxylase6.3.4.140.446
3adaNADSubunit alpha of sarocosine oxidase/0.446
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.446
3c3dFO12-phospho-L-lactate transferase/0.446
3falREARetinoic acid receptor RXR-alpha/0.446
3q95ESLEstrogen receptor/0.446
3rthRTHBeta-secretase 13.4.23.460.446
3v9v21LPeroxisome proliferator-activated receptor gamma/0.446
3vrwYS5Vitamin D3 receptor/0.446
3vt8YI3Vitamin D3 receptor/0.446
4ax8ADPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.446
4cdmFO1Deoxyribodipyrimidine photolyase/0.446
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4g1y0VOVitamin D3 receptor A/0.446
4g210VPVitamin D3 receptor A/0.446
4j0s1H3Bromodomain-containing protein 4/0.446
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.446
4o4fATPKinase/0.446
4rupH97Vitamin D3 receptor A/0.446
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
5bsrCOA4-coumarate--CoA ligase 26.2.1.120.446
5dxgESTEstrogen receptor/0.446
5e8xSTUTGF-beta receptor type-12.7.11.300.446
1axwMTXThymidylate synthase/0.445
1dr4HBIDihydrofolate reductase1.5.1.30.445
1fd0254Retinoic acid receptor gamma/0.445
1iiuRTLRetinol-binding protein 4/0.445
1m17AQ4Epidermal growth factor receptor2.7.10.10.445
1ouk084Mitogen-activated protein kinase 14/0.445
1pd9CO4Dihydrofolate reductase1.5.1.30.445
1revTB9Gag-Pol polyprotein2.7.7.490.445
1s3vTQDDihydrofolate reductase1.5.1.30.445
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.445
1sqpMYXCytochrome b/0.445
1txtCAAHMG-CoA synthase/0.445
2fwzH71Heat shock protein HSP 90-alpha/0.445
2nv7555Estrogen receptor beta/0.445
2opqHBQGag-Pol polyprotein2.7.7.490.445
2q70DC8Estrogen receptor/0.445
2wkmPFYHepatocyte growth factor receptor2.7.10.10.445
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.445
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.445
3hz5Z64Heat shock protein HSP 90-alpha/0.445
3lfeZ84Mitogen-activated protein kinase 14/0.445
3qj5022Alcohol dehydrogenase class-31.1.1.10.445
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4gevCB3Thymidylate synthase/0.445
4h1j0YHProtein-tyrosine kinase 2-beta2.7.10.20.445
4k4j1O8Retinoic acid receptor RXR-alpha/0.445
4lsjLSJGlucocorticoid receptor/0.445
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.445
4zqcF6FTryptophan synthase alpha chain/0.445
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.445
5c8a5ADProbable transcriptional regulator/0.445
1errRALEstrogen receptor/0.444
1fk9EFZGag-Pol polyprotein2.7.7.490.444
1jlqSBNGag-Pol polyprotein2.7.7.490.444
1t0iFMNNAD(P)H-dependent FMN reductase LOT6/0.444
1tduDURThymidylate synthase/0.444
1uy6PU3Heat shock protein HSP 90-alpha/0.444
1w4zNAPPutative ketoacyl reductase1.3.10.444
2atiIHUGlycogen phosphorylase, liver form2.4.1.10.444
2d06ESTSulfotransferase 1A12.8.2.10.444
2ed3SAHDiphthine synthase/0.444
2fdyD4GCytochrome P450 2A61.14.130.444
2p4iMR9Angiopoietin-1 receptor2.7.10.10.444
2pupADPMethylthioribose kinase2.7.1.1000.444
2vdvSAMtRNA (guanine-N(7)-)-methyltransferase/0.444
2ze2T27Gag-Pol polyprotein2.7.7.490.444
3antS82Bifunctional epoxide hydrolase 23.3.2.100.444
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.444
3fzt4JZProtein-tyrosine kinase 2-beta2.7.10.20.444
3glmCOOGlutaconyl-CoA decarboxylase alpha subunit/0.444
3iisPIDPeridinin-chlorophyll a-binding protein 1, chloroplastic/0.444
3imxB84Glucokinase2.7.1.20.444
3iqeH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.444
3l034OHEstrogen receptor/0.444
3o6o94MHeat shock protein 83/0.444
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
3uibSB2Putative mitogen-activated protein kinase/0.444
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.444
4aqlTXCGuanine deaminase3.5.4.30.444
4g20484Vitamin D3 receptor A/0.444
4g3rCAMCamphor 5-monooxygenase1.14.15.10.444
4gg70J8Hepatocyte growth factor receptor2.7.10.10.444
4i421HA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.444
4j4vSVRNucleocapsid protein/0.444
4lgaA2OAbscisic acid receptor PYL2/0.444
4pxmESTEstrogen receptor/0.444
4ruoBIVVitamin D3 receptor A/0.444
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.444
4yekTHMThymidine phosphorylase/0.444
5kf2ACOPredicted acetyltransferase/0.444
5k2cZMAAdenosine receptor A2a/0.444
3uzaT4GAdenosine receptor A2a/0.444
1ci7CB3Thymidylate synthase2.1.1.450.443
1cjcFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.443
1kt6RTLRetinol-binding protein 4/0.443
1l0lFMXCytochrome b/0.443
1x8b824Wee1-like protein kinase2.7.10.20.443
1x8lOXRRetinol dehydratase/0.443
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2a8sGTPU8 snoRNA-decapping enzyme/0.443
2bu9HFVIsopenicillin N synthase1.21.3.10.443
2l98STLTroponin C, slow skeletal and cardiac muscles/0.443
2qgtEEDEstrogen receptor/0.443
2yac937Serine/threonine-protein kinase PLK12.7.11.210.443
2yatEEUEstrogen receptor/0.443
3c3eFO12-phospho-L-lactate transferase/0.443
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
3i0rRT3Gag-Pol polyprotein2.7.7.490.443
3naxMP73-phosphoinositide-dependent protein kinase 12.7.11.10.443
3nga3NGCasein kinase II subunit alpha2.7.11.10.443
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.443
3p6oETGCamphor 5-monooxygenase1.14.15.10.443
3pd4A3GThreonine--tRNA ligase6.1.1.30.443
3pg3DG7Mitogen-activated protein kinase 14/0.443
4eilCB3Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.443
4ez8DHFThymidylate synthase2.1.1.450.443
4f1mACPProbable serine/threonine-protein kinase roco42.7.11.10.443
4fsa0V3Queuine tRNA-ribosyltransferase2.4.2.290.443
4h4m494Gag-Pol polyprotein2.7.7.490.443
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.443
4i5i4I5NAD-dependent protein deacetylase sirtuin-13.5.10.443
4jq3ZOMAldo-keto reductase family 1 member C2/0.443
4kugNAD3-hydroxybutyryl-CoA dehydrogenase/0.443
4l49CAMCamphor 5-monooxygenase1.14.15.10.443
4mv1ADPBiotin carboxylase6.3.4.140.443
4uyg73BBromodomain-containing protein 2/0.443
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.443
1cqsEQUSteroid Delta-isomerase5.3.3.10.442
1e3vDXCSteroid Delta-isomerase5.3.3.10.442
1g3mPCQEstrogen sulfotransferase2.8.2.40.442
1jx0DFVChalcone--flavonone isomerase 15.5.1.60.442
1mc5AHEAlcohol dehydrogenase class-31.1.1.10.442
1nc1MTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.442
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.442
1rkgVD1Vitamin D3 receptor/0.442
1v79FR7Adenosine deaminase3.5.4.40.442
1zgaHMKIsoflavone 4'-O-methyltransferase/0.442
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.442
2cppCAMCamphor 5-monooxygenase1.14.15.10.442
2gpvOHTEstrogen-related receptor gamma/0.442
2x7gPVBSRSF protein kinase 22.7.11.10.442
3a8wATPProtein kinase C iota type2.7.11.130.442
3aqaBYHBromodomain-containing protein 2/0.442
3bejMUFBile acid receptor/0.442
3h1jSMACytochrome b/0.442
3ha5SFGHydroxymycolate synthase MmaA42.1.10.442
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.442
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3ipq965Oxysterols receptor LXR-alpha/0.442
3mdvCL6Cholesterol 24-hydroxylase/0.442
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.442
3p2oNADBifunctional protein FolD/0.442
3p6mDSOCamphor 5-monooxygenase1.14.15.10.442
3pl8FADPyranose 2-oxidase/0.442
3v49PK0Androgen receptor/0.442
3vqvANPPyrrolysine--tRNA ligase/0.442
3vrvYSDVitamin D3 receptor/0.442
3w5p4OAVitamin D3 receptor/0.442
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4b8wGDPGDP-L-fucose synthase1.1.1.2710.442
4dcaADPAminoglycoside phosphotransferase/0.442
4dm6TTBRetinoic acid receptor beta/0.442
4fhh0U3Vitamin D3 receptor A/0.442
4j0r1H2Bromodomain-containing protein 4/0.442
4jl6ADPAdenylate kinase/0.442
4nc3ERM5-hydroxytryptamine receptor 2B/0.442
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.442
5jtbZMAAdenosine receptor A2a/0.442
3reyXACAdenosine receptor A2a/0.442
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.441
1dr5NAPDihydrofolate reductase1.5.1.30.441
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
1mznBM6Retinoic acid receptor RXR-alpha/0.441
1o5iNAD3-oxoacyl-(Acyl carrier protein) reductase/0.441
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.441
1uymPU3Heat shock protein HSP 90-beta/0.441
1uzwCDHIsopenicillin N synthase1.21.3.10.441
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
1yinCM3Estrogen receptor/0.441
1zaf789Estrogen receptor beta/0.441
2cy2ACOProbable acetyltransferase/0.441
2f2cAP9Cyclin-dependent kinase 62.7.11.220.441
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.441
2fpcSCGStrictosidine synthase4.3.3.20.441
2oh4GIGVascular endothelial growth factor receptor 22.7.10.10.441
2pujHPZ2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.441
2qboCAMCamphor 5-monooxygenase1.14.15.10.441
2qcxPF1Aminopyrimidine aminohydrolase/0.441
2r6jNDPEugenol synthase 11.1.1.3180.441
2vbpVB1Isopenicillin N synthase1.21.3.10.441
2x1eX1EAcyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form2.3.1.1640.441
2xgs44PUncharacterized protein/0.441
2zb8IMNProstaglandin reductase 21.3.1.480.441
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3dyaPZLGag-Pol polyprotein2.7.7.490.441
3ictADPCoenzyme A disulfide reductase/0.441
3llaACPMyosin heavy chain kinase A2.7.11.70.441
3nr4PYVAbscisic acid receptor PYL2/0.441
3rpr25ZCyclin-dependent kinase 22.7.11.220.441
3s79ASDAromatase1.14.14.140.441
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.441
4a84DXCMajor pollen allergen Bet v 1-A/0.441
4bb2STRCorticosteroid-binding globulin/0.441
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4fdpFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.441
4m8hR4MRetinoic acid receptor RXR-alpha/0.441
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.441
1hvyD16Thymidylate synthase2.1.1.450.440
1jlcFTCGag-Pol polyprotein2.7.7.490.440
1jxzBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.440
1nzyBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.440
1pz1NAPGeneral stress protein 69/0.440
1s0xC3SNuclear receptor ROR-alpha/0.440
1tvrTB9Gag-Pol polyprotein2.7.7.490.440
2e1zB4PPropionate kinase/0.440
2kceD16Thymidylate synthase/0.440
2p1t3TNRetinoic acid receptor RXR-alpha/0.440
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.440
2uxoTACHTH-type transcriptional regulator TtgR/0.440
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.440
2zaxCAMCamphor 5-monooxygenase1.14.15.10.440
3dlgGWEGag-Pol polyprotein2.7.7.490.440
3gwlFADFAD-linked sulfhydryl oxidase1.8.3.20.440
3itzP66Mitogen-activated protein kinase 14/0.440
3otqMZLBifunctional epoxide hydrolase 23.3.2.100.440
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.440
4a9iP9IBromodomain-containing protein 2/0.440
4at2ASDPossible succinate dehydrogenase/0.440
4az0S61Lysosomal protective protein3.4.16.50.440
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.440
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.440
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.440
4flpJQ1Bromodomain testis-specific protein/0.440
4gk2L66Ephrin type-A receptor 32.7.10.10.440
4i2pG73Gag-Pol polyprotein2.7.7.490.440
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.440
6cp4CAMCamphor 5-monooxygenase1.14.15.10.440