sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3daf | FEG | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3daf | FEG | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 1.000 | |
| 3dag | FEG | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.811 | |
| 3f47 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.701 | |
| 3h65 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.692 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.672 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.495 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.494 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.493 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.484 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.484 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.483 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.483 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.483 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.482 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.480 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.480 | |
| 3unk | 0BY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.479 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.479 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.478 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.477 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 1zdw | FLV | Prenyltransferase | / | 0.476 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.476 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.475 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.475 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.475 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.475 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.475 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.474 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.474 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.473 | |
| 1ppj | ANY | Cytochrome b | / | 0.473 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.473 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.473 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.472 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.472 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.472 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.471 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.471 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.471 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.471 | |
| 4l8u | 9AZ | Serum albumin | / | 0.471 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.470 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.470 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.470 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.470 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.470 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.469 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.469 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.469 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.469 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.469 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.469 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.469 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.469 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.468 | |
| 3my5 | RFZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.468 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.467 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.467 | |
| 3zuy | TCH | Transporter | / | 0.467 | |
| 4j3d | 1JS | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.467 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.467 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.466 | |
| 1vza | UMP | Thymidylate synthase | / | 0.466 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.466 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.466 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.466 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.465 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.465 | |
| 2uw0 | GVK | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.465 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.465 | |
| 4eu5 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.465 | |
| 4gkv | NAD | Alcohol dehydrogenase, propanol-preferring | 1.1.1.1 | 0.465 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.465 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.465 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.464 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.464 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.464 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.464 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.464 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.464 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.464 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.464 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.464 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.464 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.464 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.463 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.463 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.463 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.463 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.463 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 5e8j | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.463 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.462 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.462 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.462 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.462 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.462 | |
| 4h4y | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.462 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.462 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.461 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.461 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.461 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.461 | |
| 1hwz | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.460 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.460 | |
| 1tlc | F89 | Thymidylate synthase | / | 0.460 | |
| 3fpj | SAM | Uncharacterized protein | / | 0.460 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.460 | |
| 3r9o | Z71 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.460 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.460 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.460 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.460 | |
| 1c70 | L75 | Protease | / | 0.459 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1tys | DHF | Thymidylate synthase | / | 0.459 | |
| 2fto | TMP | Thymidylate synthase | / | 0.459 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.459 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.459 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.459 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.459 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.459 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.459 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.459 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.459 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.458 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.458 | |
| 2bxm | IMN | Serum albumin | / | 0.458 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.458 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.458 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.458 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.458 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.458 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.458 | |
| 5kje | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.457 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.457 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.457 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.457 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.457 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 5kjc | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.457 | |
| 1jgt | APC | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.456 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.456 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.456 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.456 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.456 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.455 | |
| 1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.455 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.455 | |
| 1i5b | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.455 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.455 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.455 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.455 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.455 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.455 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.455 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.455 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.455 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.455 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.455 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.455 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.455 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.455 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.455 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.455 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.455 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.455 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.454 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.454 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.454 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.454 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.454 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.454 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.454 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.454 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.454 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4e2b | FMN | Dehydrogenase | / | 0.454 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.454 | |
| 4hjf | C2E | GGDEF family protein | / | 0.454 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.453 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.453 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.453 | |
| 2eka | SAH | Diphthine synthase | / | 0.453 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.453 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.453 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.453 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.453 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.453 | |
| 3l9h | EMQ | Kinesin-like protein KIF11 | / | 0.453 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 4aic | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.453 | |
| 4kwh | NAP | Reductase homolog | / | 0.453 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.452 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.452 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.452 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.452 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.452 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.452 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.452 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2f1k | NAP | Prephenate dehydrogenase | / | 0.452 | |
| 2jam | J60 | Calcium/calmodulin-dependent protein kinase type 1G | 2.7.11.17 | 0.452 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.452 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.452 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.452 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.452 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.452 | |
| 3u9e | COA | Lmo1369 protein | / | 0.452 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.452 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.452 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4lch | 1WN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.452 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 1gij | 2PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.451 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.451 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.451 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.451 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.451 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.451 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.451 | |
| 4lcf | 1WL | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.451 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.451 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1hdz | NAD | Alcohol dehydrogenase 1B | 1.1.1.1 | 0.450 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.450 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.450 | |
| 2xvv | 9DN | Serum albumin | / | 0.450 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.450 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.450 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.450 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.450 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.450 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.449 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.449 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.449 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.449 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.449 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.449 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.449 | |
| 1tys | TMP | Thymidylate synthase | / | 0.449 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.449 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.449 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.449 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.449 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.449 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.449 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.449 | |
| 2ydx | STL | Methionine adenosyltransferase 2 subunit beta | / | 0.449 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.449 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.449 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.449 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.449 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.449 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.449 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4e5n | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.449 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.449 | |
| 5cdt | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.448 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.448 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1jvs | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.448 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.448 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2owu | SAH | Diphthine synthase | / | 0.448 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.448 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.448 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.448 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.448 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.448 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.448 | |
| 3cf0 | ADP | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.448 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.448 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.448 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.448 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.448 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.448 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.448 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 4fko | 20K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.448 | |
| 4nfh | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.447 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1ie4 | T44 | Transthyretin | / | 0.447 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.447 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.447 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.447 | |
| 2eph | ASP_TRP_ASN | Fructose-bisphosphate aldolase | 4.1.2.13 | 0.447 | |
| 2exm | ZIP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.447 | |
| 2h3w | COA | Carnitine O-acetyltransferase | 2.3.1.7 | 0.447 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.447 | |
| 2udp | UPP | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.447 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2zxu | DST | tRNA dimethylallyltransferase | 2.5.1.75 | 0.447 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3fnl | SHA | Lactoperoxidase | / | 0.447 | |
| 3hdy | FAD | UDP-galactopyranose mutase | / | 0.447 | |
| 3iw5 | DF3 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.447 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.447 | |
| 3r3c | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.447 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.447 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.447 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.447 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3zo1 | SIJ | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.447 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.447 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.447 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.446 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.446 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.446 | |
| 1pz0 | NAP | Protein IolS | 1.1.1 | 0.446 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.446 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.446 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 3vet | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.446 | |
| 3w4y | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.446 | |
| 3zsi | 52P | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.446 | |
| 4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.446 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.446 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.446 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.446 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.446 | |
| 5cds | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 5dp2 | NAP | CurF | / | 0.446 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.445 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.445 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.445 | |
| 1rx4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.445 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.445 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.445 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.445 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.445 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.445 | |
| 2od7 | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.445 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.445 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.445 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.445 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.445 | |
| 3cbs | R12 | Cellular retinoic acid-binding protein 2 | / | 0.445 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.445 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.445 | |
| 3iw6 | PP0 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.445 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 3nbv | ANP | Ketohexokinase | / | 0.445 | |
| 3roc | 29A | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.445 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3vth | AP2 | Carbamoyltransferase | / | 0.445 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.445 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.445 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.445 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4hxy | NDP | Plm1 | / | 0.445 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.445 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.445 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.445 | |
| 1ke8 | LS4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1osv | CHC | Bile acid receptor | / | 0.444 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.444 | |
| 1ptj | SND | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.444 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.444 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.444 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.444 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.444 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.444 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 4neu | Q1A | Receptor-interacting serine/threonine-protein kinase 1 | 2.7.11.1 | 0.444 | |
| 4pkh | ADP | Actin, alpha skeletal muscle | / | 0.444 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 5kj1 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.444 | |
| 1bpj | UMP | Thymidylate synthase | / | 0.443 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.443 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.443 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.443 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.443 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 1pxl | CK4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.443 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.443 | |
| 2uw7 | GVP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2vhw | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.443 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.443 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.443 | |
| 3eya | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.443 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.443 | |
| 3i59 | N6S | CRP-like cAMP-activated global transcriptional regulator | / | 0.443 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.443 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.443 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.443 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.443 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4l4x | NDP | AmphI | / | 0.443 | |
| 4l9k | EHF | Serum albumin | / | 0.443 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.443 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.442 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1mgo | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.442 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 2a1u | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.442 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2bxq | IMN | Serum albumin | / | 0.442 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.442 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 2j7p | GNP | Signal recognition particle protein | / | 0.442 | |
| 2j7p | GNP | Signal recognition particle receptor FtsY | / | 0.442 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2p5f | SAH | Diphthine synthase | / | 0.442 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.442 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.442 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.442 | |
| 3b2e | ADP | ATPase GET3 | / | 0.442 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.442 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 3py0 | SU9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3r8l | Z30 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.442 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.442 | |
| 4irn | FAD | AnaB | / | 0.442 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.442 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.442 | |
| 4pgh | SAM | Caffeic acid O-methyltransferase | / | 0.442 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.442 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.442 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.441 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.441 | |
| 1w78 | PD8 | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.441 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.441 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.441 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.441 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.441 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.441 | |
| 2vrx | 447 | Aurora kinase B-A | 2.7.11.1 | 0.441 | |
| 2vtj | LZ4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.441 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.441 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.441 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.441 | |
| 3zux | TCH | Transporter | / | 0.441 | |
| 4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.441 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.441 | |
| 4ks7 | X4Z | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.441 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.441 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.441 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.441 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.440 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1r78 | FMD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.440 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1vfr | FMN | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.440 | |
| 1vzb | UMP | Thymidylate synthase | / | 0.440 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.440 | |
| 2gu8 | 796 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.440 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.440 | |
| 2xvw | 9NR | Serum albumin | / | 0.440 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.440 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 3ag9 | A02 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 3av7 | KYA | Uncharacterized protein | / | 0.440 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.440 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.440 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.440 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4g3e | 0WC | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.440 | |
| 4j16 | NAD | NAD/NADP transhydrogenase alpha subunit 1 | / | 0.440 | |
| 4j1r | I5R | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.440 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
| 4k42 | ADP | Actin, alpha skeletal muscle | / | 0.440 | |
| 4k8a | K8A | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 4ng5 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 4nu5 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.440 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.440 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 |