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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3pchCHBProtocatechuate 3,4-dioxygenase beta chain1.13.11.3

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3pchCHBProtocatechuate 3,4-dioxygenase beta chain1.13.11.31.000
3pcg4HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.746
3pcg4HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.746
3mflDHYProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.625
3mflDHYProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.625
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.616
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.616
3pcnDHYProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.612
3pcnDHYProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.612
2y3pSM8DNA gyrase subunit A/0.512
2w02ATPAcsD/0.511
1f9aATPNicotinamide-nucleotide adenylyltransferase/0.509
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.499
2v58LZJBiotin carboxylase6.3.4.140.497
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.492
3jziJZLBiotin carboxylase6.3.4.140.491
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.491
1touB1VFatty acid-binding protein, adipocyte/0.490
2lbaCHOFatty acid binding protein 6/0.489
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.488
1yw8A75Methionine aminopeptidase 2/0.488
3fhxPXLPyridoxal kinase2.7.1.350.488
3lfzADPUncharacterized protein MJ1225/0.488
2zsiGA4Gibberellin receptor GID1A30.487
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.487
4bl5GFBGDP-L-fucose synthase1.1.1.2710.486
1towCRZFatty acid-binding protein, adipocyte/0.485
3v0n4GWHisto-blood group ABO system transferase/0.485
4yaw2AMNADPH--cytochrome P450 reductase/0.485
1xddAAYIntegrin alpha-L/0.484
2pncCLUPrimary amine oxidase, liver isozyme/0.484
2ea2F77Methionine aminopeptidase 2/0.483
4f3gKAIGlutamate receptor 3/0.483
4nhyPD2Prolyl 3-hydroxylase OGFOD11.14.110.483
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.482
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.482
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.482
3qwbNDPProbable quinone oxidoreductase1.6.5.50.482
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.482
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.480
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.480
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.480
1cq8PY6Aspartate aminotransferase2.6.1.10.479
3zeiAWHO-acetylserine sulfhydrylase/0.479
3fr4F8AFatty acid-binding protein, adipocyte/0.478
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.478
4ho4THMGlucose-1-phosphate thymidylyltransferase/0.478
1lb9DNQGlutamate receptor 2/0.477
3fr5I4AFatty acid-binding protein, adipocyte/0.477
4b4vL34Bifunctional protein FolD/0.477
1ascNPLAspartate aminotransferase2.6.1.10.476
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.476
1i59ANPChemotaxis protein CheA2.7.13.30.475
2v5aLZLBiotin carboxylase6.3.4.140.475
2x0fTRHWsaF/0.475
4fhf0TTSpore photoproduct lyase/0.475
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.475
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.475
1fw0KAIGlutamate receptor 2/0.473
2nnqT4BFatty acid-binding protein, adipocyte/0.473
3fhxPLPPyridoxal kinase2.7.1.350.473
3keuATPPyridoxal kinase2.7.1.350.473
1cq6PY4Aspartate aminotransferase2.6.1.10.472
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.472
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.472
1vbiNADMalate/L-lactate dehydrogenase family protein/0.472
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.472
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.472
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.472
4m4922YL-lactate dehydrogenase A chain1.1.1.270.472
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.471
3l2kPXCEhpF/0.471
3nmpPYVAbscisic acid receptor PYL2/0.471
4b8zGDPGDP-L-fucose synthase1.1.1.2710.471
4rh10TTSpore photoproduct lyase/0.471
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.471
1qjfACSIsopenicillin N synthase1.21.3.10.470
1u1gBBBUridine phosphorylase2.4.2.30.470
1uymPU3Heat shock protein HSP 90-beta/0.470
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
3kozZ97D-ornithine 4,5-aminomutase subunit beta/0.470
4kc1WS1Histo-blood group ABO system transferase/0.470
1clqGDPDNA-directed DNA polymerase/0.469
1h51FMNPentaerythritol tetranitrate reductase/0.469
1jpaANPEphrin type-B receptor 22.7.10.10.469
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.469
1qiqACCIsopenicillin N synthase1.21.3.10.469
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.469
2xvv9DNSerum albumin/0.469
3cr0809Wee1-like protein kinase2.7.10.20.469
4bfxZVXPantothenate kinase2.7.1.330.469
4jbxSK7Thymidine kinase/0.469
4u0zAPCAdenosine monophosphate-protein transferase FICD2.7.7.n10.469
4zu44TGWxcM-like protein/0.469
2v59LZKBiotin carboxylase6.3.4.140.468
2ejzSAHDiphthine synthase/0.467
2gjnFMNNitronate monooxygenase1.13.12.160.467
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.467
3aosJH2Hemolymph juvenile hormone binding protein/0.467
3eblGA4Gibberellin receptor GID1/0.467
3ed1GA3Gibberellin receptor GID1/0.467
3qgi33FGenome polyprotein2.7.7.480.467
4jxrACOAcetyltransferase/0.467
4tqqUQ1Reaction center protein L chain/0.467
2pakTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.466
2zsaADPPantothenate kinase2.7.1.330.466
3c3xNAPEugenol synthase 11.1.1.3180.466
3fr28CAFatty acid-binding protein, adipocyte/0.466
3hk1B64Fatty acid-binding protein, adipocyte/0.466
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.466
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
4qxq1YEStimulator of interferon genes protein/0.466
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.465
2dvoITTdITP/XTP pyrophosphatase3.6.1.190.465
2e0iFADDNA photolyase/0.465
2x3jATPAcsD/0.465
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.465
4gk3L87Ephrin type-A receptor 32.7.10.10.465
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.464
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.464
1re0AFBADP-ribosylation factor 1/0.464
1re0AFBARF guanine-nucleotide exchange factor 1/0.464
1rftPXMPyridoxal kinase2.7.1.350.464
1rp4FADEndoplasmic oxidoreductin-11.8.40.464
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.464
1xjqADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.464
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.464
2xyuQ9GEphrin type-A receptor 42.7.10.10.464
2y71CB63-dehydroquinate dehydratase4.2.1.100.464
3af1GDPPantothenate kinase2.7.1.330.464
3i2834NBifunctional epoxide hydrolase 23.3.2.100.464
4dpy2P0Mevalonate diphosphate decarboxylase/0.464
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.464
5bn3ADPV-type ATP synthase alpha chain/0.464
5bn3ADPNEQ263/0.464
1bwlFMNNADPH dehydrogenase 11.6.99.10.463
1og1TADT-cell ecto-ADP-ribosyltransferase 2/0.463
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.463
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.463
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.463
3arvSAUChitinase A/0.463
3fhyATPPyridoxal kinase2.7.1.350.463
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.463
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
4ivrN50Thymidine kinase/0.463
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.463
1lbbKAIGlutamate receptor 2/0.462
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.462
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.462
2zshGA3Gibberellin receptor GID1A30.462
3v0o4GWHisto-blood group ABO system transferase/0.462
4f1yCNIGlutamate receptor 3/0.462
4mv4ACPBiotin carboxylase6.3.4.140.462
4yao2AMNADPH--cytochrome P450 reductase/0.462
5ebuFMNLactate oxidase/0.462
2oegUPGUDP-glucose pyrophosphorylase/0.461
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.461
2rhrEMOPutative ketoacyl reductase1.3.10.461
3gueUPGUTP-glucose-1-phosphate uridylyltransferase 2, putative/0.461
3igpDT7Carbonic anhydrase 24.2.1.10.461
3ogwIMNLactoperoxidase1.11.1.70.461
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.461
4b4w9L9Bifunctional protein FolD/0.461
4o4fATPKinase/0.461
5fd8A5APutative carboxypeptidase yocD/0.461
4mqt2CUMuscarinic acetylcholine receptor M2/0.461
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1i5bANPChemotaxis protein CheA2.7.13.30.460
1x8lOXRRetinol dehydratase/0.460
2dxfGNPNucleoside diphosphate kinase2.7.4.60.460
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.460
2z4w749Geranylgeranyl pyrophosphate synthase/0.460
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.460
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.460
3q3cNADNAD-dependent L-serine dehydrogenase/0.460
3qiyQI1Botulinum neurotoxin type A3.4.24.690.460
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.460
4fflADPUncharacterized protein/0.460
4k36SAMAnaerobic sulfatase-maturating enzyme1.8.980.460
1ankANPAdenylate kinase/0.459
1gpnHUBAcetylcholinesterase3.1.1.70.459
1oc1ASVIsopenicillin N synthase1.21.3.10.459
1pqc444Oxysterols receptor LXR-beta/0.459
2fhnBNIAvidin-related protein 4/5/0.459
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
2vbdV10Isopenicillin N synthase1.21.3.10.459
2xltNA0Putative flavin-containing monooxygenase/0.459
2xvw9NRSerum albumin/0.459
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.459
3thrC2FGlycine N-methyltransferase2.1.1.200.459
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.459
4klrCHDFerrochelatase, mitochondrial4.99.1.10.459
4rvgTYDD-mycarose 3-C-methyltransferase/0.459
1mrqSTRAldo-keto reductase family 1 member C1/0.458
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
2acwUPGGlycosyltransferase/0.458
2g247IGRenin3.4.23.150.458
2oliIOPBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.458
2y60M8FIsopenicillin N synthase1.21.3.10.458
3hz5Z64Heat shock protein HSP 90-alpha/0.458
3ko8NADNAD-dependent epimerase/dehydratase/0.458
3znsNU7Histone deacetylase 73.5.1.980.458
4bis8HQLysine-specific demethylase 4A1.14.110.458
4gk2L66Ephrin type-A receptor 32.7.10.10.458
4l4xNDPAmphI/0.458
4uugPXGBranched-chain amino acid aminotransferase, putative/0.458
4y9uNAPNADPH--cytochrome P450 reductase/0.458
4yal2AMNADPH--cytochrome P450 reductase/0.458
1kmyBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.457
1maqPGUAspartate aminotransferase, mitochondrial2.6.1.10.457
1obnASVIsopenicillin N synthase1.21.3.10.457
2ptfFMNUncharacterized protein MTH_863/0.457
2tohHBITyrosine 3-monooxygenase1.14.16.20.457
2yx6ADPUncharacterized protein/0.457
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.457
3ge7AFQQueuine tRNA-ribosyltransferase2.4.2.290.457
3lfcZ86Mitogen-activated protein kinase 14/0.457
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.457
4aoaIK2Beta-phenylalanine transaminase2.6.10.457
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.457
4bfvZVVPantothenate kinase2.7.1.330.457
4bfzZVZPantothenate kinase2.7.1.330.457
4bqwQNMEgl nine homolog 1/0.457
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.457
4hy6FJ1Heat shock protein HSP 90-alpha/0.457
4mv1ADPBiotin carboxylase6.3.4.140.457
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.457
1ao8MTXDihydrofolate reductase1.5.1.30.456
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.456
1m9nAMZBifunctional purine biosynthesis protein PURH2.1.2.30.456
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.456
2aazCB3Thymidylate synthase2.1.1.450.456
2g226IGRenin3.4.23.150.456
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.456
3jzfJZKBiotin carboxylase6.3.4.140.456
3v0p4GWHisto-blood group ABO system transferase/0.456
4ba5PXGProbable aminotransferase/0.456
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.456
1aj22PHDihydropteroate synthase/0.455
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.455
1s9dAFBCytohesin-2/0.455
1s9dAFBADP-ribosylation factor 1/0.455
1vf2GTXGlutathione S-transferase 32.5.1.180.455
1xmmM7Gm7GpppX diphosphatase3.6.1.590.455
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
3c1y2BADNA integrity scanning protein DisA/0.455
3crzFADFerredoxin--NADP+ reductase/0.455
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3gc4AAQQueuine tRNA-ribosyltransferase2.4.2.290.455
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
4hhy15RPoly [ADP-ribose] polymerase 12.4.2.300.455
4ho9UTPGlucose-1-phosphate thymidylyltransferase/0.455
4rphGDUUDP-galactopyranose mutase5.4.99.90.455
1cqp803Integrin alpha-L/0.454
1jedADPSulfate adenylyltransferase/0.454
1u1cBAUUridine phosphorylase2.4.2.30.454
2fypRDEEndoplasmin/0.454
2g1s4IGRenin3.4.23.150.454
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.454
2x0rNADMalate dehydrogenase/0.454
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.454
3oikWZBCarbonic anhydrase 24.2.1.10.454
3tr05GPGuanylate kinase/0.454
4bz8J38Histone deacetylase/0.454
1i5aACPChemotaxis protein CheA2.7.13.30.453
1rx8FOLDihydrofolate reductase1.5.1.30.453
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.453
2bunFADAppA protein/0.453
2e0nSAHPrecorrin-2 C20-methyltransferase/0.453
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.453
2pa7TYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.453
2qjoNADBifunctional NMN adenylyltransferase/Nudix hydrolase2.7.7.10.453
2ydxSTLMethionine adenosyltransferase 2 subunit beta/0.453
4ap1NAPSteroid monooxygenase/0.453
4dlcUMPDeoxyuridine triphosphatase, putative/0.453
4dya0MFNucleoprotein/0.453
4gd40WSLysine-specific demethylase 4A1.14.110.453
4u0mGTPCyclic GMP-AMP synthase/0.453
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.452
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.452
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.452
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.452
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.452
3imgBZ3Pantothenate synthetase6.3.2.10.452
3p5lIT5Carbonic anhydrase 24.2.1.10.452
3pz3PZ3Geranylgeranyl transferase type-2 subunit beta2.5.1.600.452
3zkyWT4Isopenicillin N synthase1.21.3.10.452
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.452
4xo7ASDAldo-keto reductase family 1 member C2/0.452
4y7cNAPNADPH--cytochrome P450 reductase/0.452
4ycoFMNtRNA-dihydrouridine(16) synthase/0.452
5c80URIUridine phosphorylase/0.452
1dr3HBIDihydrofolate reductase1.5.1.30.451
1ej2NADNicotinamide-nucleotide adenylyltransferase2.7.7.10.451
1if8SBSCarbonic anhydrase 24.2.1.10.451
1szfFMNCytochrome b2, mitochondrial1.1.2.30.451
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.451
2cjeDUNDUTPase/0.451
2gesCOKPantothenate kinase2.7.1.330.451
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.451
3biz61EWee1-like protein kinase2.7.10.20.451
3drcMTXDihydrofolate reductase1.5.1.30.451
3g0cRUFDipeptidyl peptidase 4/0.451
4awtFMNNADH:flavin oxidoreductase Sye1/0.451
4bgbADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases/0.451
4ey6GNTAcetylcholinesterase3.1.1.70.451
4gdpFADPolyamine oxidase FMS1/0.451
4u7wNDPMxaA/0.451
1g7uPEP2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.450
1j8uH4BPhenylalanine-4-hydroxylase1.14.16.10.450
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.450
2e4nSAHDiphthine synthase/0.450
2g8yNADHydroxycarboxylate dehydrogenase B/0.450
2gqaFMNNADH:flavin oxidoreductase Sye1/0.450
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.450
2xdaJPS3-dehydroquinate dehydratase4.2.1.100.450
3b9lAZZSerum albumin/0.450
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3f03FMNPentaerythritol tetranitrate reductase/0.450
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.450
3m31FADEndoplasmic oxidoreductin-11.8.40.450
3oimVZ5Carbonic anhydrase 24.2.1.10.450
4b65NDPL-ornithine N(5)-monooxygenase/0.450
4bb3KKAIsopenicillin N synthase1.21.3.10.450
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.450
4g2fC07Ephrin type-A receptor 32.7.10.10.450
4o4eATPKinase/0.450
4qx5CMPcGMP-dependent protein kinase 12.7.11.120.450
4qxr1YEStimulator of interferon genes protein/0.450
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.450
1f20NAPNitric oxide synthase, brain1.14.13.390.449
1fduNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1gpeFADGlucose oxidase1.1.3.40.449
1lkeDOGBilin-binding protein/0.449
1nd52BFProstatic acid phosphatase3.1.3.20.449
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.449
2c2aADPSensor histidine kinase/0.449
3eksCY9Actin-5C/0.449
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.449
3phiNDPShikimate dehydrogenase (NADP(+))/0.449
3q1fYPPBeta-lactamase/0.449
4dyn0MRNucleoprotein/0.449
4dyp0MSNucleoprotein/0.449
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.449
1oklMNSCarbonic anhydrase 24.2.1.10.448
2bqzSAHN-lysine methyltransferase KMT5A/0.448
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.448
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.448
2ojg19AMitogen-activated protein kinase 12.7.11.240.448
2xveFADPutative flavin-containing monooxygenase/0.448
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
3aklADPSerine/threonine-protein kinase CtkA2.7.11.10.448
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.448
3fznD7KBenzoylformate decarboxylase4.1.1.70.448
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.448
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.448
3qpg3QPAspartate aminotransferase2.6.1.10.448
3s8xE59Carbonic anhydrase 24.2.1.10.448
3u4o08EGenome polyprotein2.7.7.480.448
3wt0ATPCell division protein FtsA/0.448
4h6kFMNNADPH dehydrogenase 11.6.99.10.448
4kc2WS2Histo-blood group ABO system transferase/0.448
5a3cNADSIR2 family protein/0.448
5iqiGNPBifunctional AAC/APH2.3.10.448
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.447
1o9bNAIQuinate/shikimate dehydrogenase/0.447
1pf7IMHPurine nucleoside phosphorylase2.4.2.10.447
1rxjBNIStreptavidin/0.447
1tkaN3TTransketolase 12.2.1.10.447
1u1f183Uridine phosphorylase2.4.2.30.447
2b69NADUDP-glucuronic acid decarboxylase 14.1.1.350.447
2br5SAHCephalosporin hydroxylase CmcI/0.447
2h4k509Tyrosine-protein phosphatase non-receptor type 13.1.3.480.447
2ikuLIYRenin3.4.23.150.447
2o8bADPDNA mismatch repair protein Msh2/0.447
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.447
2vkeTACTetracycline repressor protein class D/0.447
2yoj8Y6Genome polyprotein2.7.7.480.447
3c0zSHHHistone deacetylase 73.5.1.980.447
3gc52MQQueuine tRNA-ribosyltransferase2.4.2.290.447
4gutFADLysine-specific histone demethylase 1B10.447
4v0s2HN3-dehydroquinate dehydratase4.2.1.100.447
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.446
1jdvADNPurine nucleoside phosphorylase/0.446
1p4aPCPPur operon repressor/0.446
2dxeGDPNucleoside diphosphate kinase2.7.4.60.446
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.446
2r0pK2CPutative FAD-monooxygenase/0.446
2rm2W43Genome polyprotein/0.446
2v2vV124-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.446
2w6zL21Biotin carboxylase6.3.4.140.446
2y6o1N1Ephrin type-A receptor 42.7.10.10.446
3bl7DD1m7GpppX diphosphatase3.6.1.590.446
3gncQQQGlutaryl-CoA dehydrogenase/0.446
3h59H59Genome polyprotein2.7.7.480.446
3hwxTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.446
3ns2PYVAbscisic acid receptor PYL2/0.446
3uf7ASP_ILE_PRO_PHEUracil-DNA glycosylase3.2.2.270.446
4cukNAID-lactate dehydrogenase/0.446
4d965PAD-cysteine desulfhydrase/0.446
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.446
4j7hTRHPCZA361.3/0.446
4jv3N32Beta-ketoacyl synthase/0.446
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.445
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.445
1g1dFSBCarbonic anhydrase 24.2.1.10.445
1i91INQCarbonic anhydrase 24.2.1.10.445
1ivrCBAAspartate aminotransferase, mitochondrial2.6.1.10.445
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.445
1z5cADPType 2 DNA topoisomerase 6 subunit B/0.445
2b3vACODiamine acetyltransferase 1/0.445
2c20NADUDP-glucose 4-epimerase/0.445
2e95B75Geranylgeranyl pyrophosphate synthase/0.445
2fzeAPRAlcohol dehydrogenase class-31.1.1.10.445
2geuCOKPantothenate kinase2.7.1.330.445
2gmsP0PPutative pyridoxamine 5-phosphate-dependent dehydrase/0.445
2qocANPEphrin type-A receptor 32.7.10.10.445
2qw034Z4-chlorobenzoyl CoA ligase/0.445
2qw8NAPEugenol synthase 11.1.1.3180.445
2vbpVB1Isopenicillin N synthase1.21.3.10.445
2wegFBVCarbonic anhydrase 24.2.1.10.445
2x0qATPAlcaligin biosynthesis protein/0.445
3atyFMNProstaglandin F2a synthase/0.445
3h1vTK1Glucokinase2.7.1.20.445
3k145352-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.445
3rimTPPTransketolase2.2.1.10.445
3rthRTHBeta-secretase 13.4.23.460.445
4dbs0HVAldo-keto reductase family 1 member C3/0.445
4dieC5PCytidylate kinase/0.445
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.445
4i6gFADCryptochrome-2/0.445
4jc51K5Stimulator of interferon genes protein/0.445
4kxjP34Nucleoprotein/0.445
4qaiFMNNADPH dehydrogenase/0.445
4uocNCNCinA-like protein/0.445
1cq7PY5Aspartate aminotransferase2.6.1.10.444
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.444
1kw9BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.444
1x8vESLLanosterol 14-alpha demethylase1.14.13.700.444
1y1rANUUridine phosphorylase2.4.2.30.444
1z6tADPApoptotic protease-activating factor 1/0.444
2dvlFADAcyl-CoA dehydrogenase/0.444
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.444
2ok7FADFerredoxin--NADP reductase, apicoplast/0.444
2on6IMHPurine nucleoside phosphorylase2.4.2.10.444
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.444
2qbr910Tyrosine-protein phosphatase non-receptor type 13.1.3.480.444
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.444
3dcsMZMCarbonic anhydrase 24.2.1.10.444
3fpzAHZThiamine thiazole synthase/0.444
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.444
3lfeZ84Mitogen-activated protein kinase 14/0.444
3vg10GTBeta-secretase 13.4.23.460.444
3vg9ZMAAdenosine receptor A2a/0.444
4bdrKAIGlutamate receptor ionotropic, kainate 2/0.444
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
5fm7ADPRuvB-like helicase/0.444
1ao05GPAmidophosphoribosyltransferase/0.443
1n1dC2GGlycerol-3-phosphate cytidylyltransferase2.7.7.390.443
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
1xpqFADPolyamine oxidase FMS1/0.443
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
2dw4FADLysine-specific histone demethylase 1A10.443
2qimZEAClass 10 plant pathogenesis-related protein/0.443
2vcxD26Hematopoietic prostaglandin D synthase/0.443
2wvlGDDMannosyl-3-phosphogylcerate synthase/0.443
3atzFMNProstaglandin F2a synthase/0.443
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.443
3otwCOAPhosphopantetheine adenylyltransferase/0.443
3to3ATPPetrobactin biosynthesis protein AsbB/0.443
3vv8B02Beta-secretase 13.4.23.460.443
4dc0NDPPutative ketoacyl reductase1.3.10.443
4fgrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.443
4jtrIZPAldo-keto reductase family 1 member C2/0.443
4xnhACON-terminal acetyltransferase A complex subunit NAT52.3.10.443
5kf2ACOPredicted acetyltransferase/0.443
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.442
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.442
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.442
1qxoFMNChorismate synthase/0.442
1thz326Bifunctional purine biosynthesis protein PURH2.1.2.30.442
1vyrFMNPentaerythritol tetranitrate reductase/0.442
2am22LGUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.442
2bf7HBIPteridine reductase 11.5.1.330.442
2qo7ANPEphrin type-A receptor 32.7.10.10.442
2vnjNAPNADPH:ferredoxin reductase/0.442
2zevIPEGeranylgeranyl pyrophosphate synthase/0.442
3au2DGTDNA polymerase beta family (X family)/0.442
3d9zD9ZCarbonic anhydrase 24.2.1.10.442
3h3sH15Collagen type IV alpha-3-binding protein/0.442
3mauPLRPutative sphingosine-1-phosphate lyase/0.442
3n19FNRXenobiotic reductase/0.442
3oafOAGDihydrofolate reductase1.5.1.30.442
3p8iFMNPentaerythritol tetranitrate reductase/0.442
3ske054Genome polyprotein2.7.7.480.442
3t85SG7Carbonic anhydrase 24.2.1.10.442
4askK0ILysine-specific demethylase 6B1.14.110.442
4b67NAPL-ornithine N(5)-monooxygenase/0.442
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.442
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.442
4jeyPLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.442
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.442
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.442
5f54TMPSingle-stranded-DNA-specific exonuclease/0.442
5kf8ACOPredicted acetyltransferase/0.442
1culFOKAdenylate cyclase type 2/0.441
1culFOKAdenylate cyclase type 5/0.441
1dr4HBIDihydrofolate reductase1.5.1.30.441
1hrvSDZGenome polyprotein/0.441
1mx0ANPType 2 DNA topoisomerase 6 subunit B/0.441
1opbRETRetinol-binding protein 2/0.441
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1rszDIHPurine nucleoside phosphorylase2.4.2.10.441
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.441
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.441
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.441
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
1ykdCMPAdenylate cyclase/0.441
1zdwFLVPrenyltransferase/0.441
1zemNADXylitol dehydrogenase/0.441
2e77FMNLactate oxidase/0.441
2f3rG5PGuanylate kinase2.7.4.80.441
2iibC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.441
2xb5I7TTetracycline repressor protein class D/0.441
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.441
3bw4FMNPutative 2-nitropropane dioxygenase/0.441
3c35KAIGlutamate receptor ionotropic, kainate 1/0.441
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.441
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3hl4CDCCholine-phosphate cytidylyltransferase A/0.441
3opxU5PSuppressor of disruption of TFIIS/0.441
3qizQI2Botulinum neurotoxin type A3.4.24.690.441
3udk095Beta-secretase 13.4.23.460.441
3uyk0CXProbable NDP-rhamnosyltransferase/0.441
3vkjFNRIsopentenyl-diphosphate delta-isomerase/0.441
4a0mNADBetaine aldehyde dehydrogenase, chloroplastic1.2.1.80.441
4b0532DBeta-secretase 13.4.23.460.441
4b7754MBeta-secretase 13.4.23.460.441
4c6zTLE3-oxoacyl-ACP synthase/0.441
4d9eLCSD-cysteine desulfhydrase/0.441
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.441
4ih71ERGenome polyprotein2.7.7.480.441
4ryvZEAProtein LlR18A/0.441
4zlaBESCytosol aminopeptidase3.4.11.10.441
5fa1C5PPutative N-acetyl glucosaminyl transferase/0.441
1bnuAL3Carbonic anhydrase 24.2.1.10.440
1ek5NADUDP-glucose 4-epimerase/0.440
1h62ANBPentaerythritol tetranitrate reductase/0.440
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.440
1swpBTNStreptavidin/0.440
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.440
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.440
2onmNADAldehyde dehydrogenase, mitochondrial1.2.1.30.440
2qoqANPEphrin type-A receptor 32.7.10.10.440
3anmSYD1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.440
3ba6AN2Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.440
3keqNADRedox-sensing transcriptional repressor Rex/0.440
3lxeTORCarbonic anhydrase 14.2.1.10.440
3sufSUEPolyprotein/0.440
4e5mNAPPhosphonate dehydrogenase1.20.1.10.440
4f3xNADPutative aldehyde dehydrogenase/0.440
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.440
4jlm1NNDeoxycytidine kinase2.7.1.740.440
4kc4WS3Histo-blood group ABO system transferase/0.440
4m83ERYOleandomycin glycosyltransferase2.4.10.440
4mo82VQCarbonic anhydrase 24.2.1.10.440
4mv3ACPBiotin carboxylase6.3.4.140.440
4yaiNAIC alpha-dehydrogenase/0.440
5bv3M7Gm7GpppX diphosphatase3.6.1.590.440
5c1gGDUHisto-blood group ABO system transferase/0.440
5hq8SAHHistone-lysine N-methyltransferase SMYD32.1.1.430.440