sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2eg8 | FOT | Dihydroorotase | 3.5.2.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2eg8 | FOT | Dihydroorotase | 3.5.2.3 | 1.000 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.520 | |
| 4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.503 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.492 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.490 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.488 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.486 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.486 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.484 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.484 | |
| 4bzb | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.484 | |
| 4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.484 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.484 | |
| 5c3j | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.484 | |
| 5c3j | UQ1 | Succinate dehydrogenase cytochrome b560 | / | 0.484 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.482 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.482 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.481 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.481 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.480 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.480 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 2ofi | ADK | 3-methyladenine DNA glycosylase I | / | 0.479 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.479 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.478 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.478 | |
| 4e31 | JHZ | Methyltransferase | / | 0.477 | |
| 1a9p | 9DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.476 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.476 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.476 | |
| 4ck2 | NVU | Integrase | / | 0.476 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.475 | |
| 2uup | LK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.475 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.475 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.474 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.474 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.474 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.473 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.473 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.472 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.472 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.472 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.472 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.472 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.472 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.471 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.471 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.471 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.471 | |
| 3p3c | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.471 | |
| 1hy3 | PPS | Estrogen sulfotransferase | 2.8.2.4 | 0.470 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.470 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.470 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.470 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.470 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.470 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.470 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.470 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.469 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.469 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.469 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.469 | |
| 2j41 | 5GP | Guanylate kinase | / | 0.469 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.469 | |
| 3bj8 | COA | Diamine acetyltransferase 1 | / | 0.469 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.469 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.469 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.469 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.468 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.468 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.468 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.468 | |
| 2xy9 | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.468 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.468 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.468 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.468 | |
| 4e2w | JHZ | Methyltransferase | / | 0.468 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.468 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.467 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.467 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.467 | |
| 4qfx | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.467 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.466 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.466 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.466 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.466 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.466 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.466 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.466 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 4d9f | DCS | D-cysteine desulfhydrase | / | 0.466 | |
| 1nd5 | 2BF | Prostatic acid phosphatase | 3.1.3.2 | 0.465 | |
| 1rp7 | TZD | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.465 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.465 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.465 | |
| 2o12 | FMN | Chorismate synthase | / | 0.465 | |
| 2tys | PLT | Tryptophan synthase beta chain | 4.2.1.20 | 0.465 | |
| 2zym | ACX | Periplasmic binding protein | / | 0.465 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.465 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.465 | |
| 3qvi | K95 | HAP protein | / | 0.465 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.465 | |
| 4rrk | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.465 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.464 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.464 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.464 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.464 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.464 | |
| 4nhm | UN9 | Prolyl 3,4-dihydroxylase TPA1 | 1.14.11 | 0.464 | |
| 5ans | RX8 | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.464 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.464 | |
| 1e2n | RCA | Thymidine kinase | / | 0.463 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.463 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.463 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.463 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.463 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.463 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.463 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.463 | |
| 4req | 5AD | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.463 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.463 | |
| 4uoc | NCN | CinA-like protein | / | 0.463 | |
| 5kj1 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.463 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.462 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.462 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.462 | |
| 2wky | IBC | Glutamate receptor ionotropic, kainate 1 | / | 0.462 | |
| 3g0c | RUF | Dipeptidyl peptidase 4 | / | 0.462 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.462 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.462 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.462 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 4e32 | DWN | Methyltransferase | / | 0.462 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.462 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.462 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.462 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.462 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2bxo | OPB | Serum albumin | / | 0.461 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.461 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.461 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.461 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.461 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.461 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.461 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 3v2u | ATP | Protein GAL3 | / | 0.461 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.460 | |
| 2aj8 | SC3 | Dipeptidyl peptidase 4 | / | 0.460 | |
| 2vdy | HCY | Corticosteroid-binding globulin | / | 0.460 | |
| 3dge | ADP | Sensor histidine kinase | / | 0.460 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.460 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.460 | |
| 5eso | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.460 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.459 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.459 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2wge | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.459 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.459 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.459 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.459 | |
| 3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.459 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.459 | |
| 4rrd | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.459 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.459 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.459 | |
| 1l8a | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.458 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.458 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.458 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.458 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.458 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.458 | |
| 4isu | IKM | Glutamate receptor 2 | / | 0.458 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.458 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.458 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.458 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.458 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.457 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.457 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.457 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.457 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.457 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.457 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.457 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.457 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.457 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.457 | |
| 3lnc | 5GP | Guanylate kinase | / | 0.457 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.457 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4lb2 | DM5 | Serum albumin | / | 0.457 | |
| 4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.457 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.457 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.456 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.456 | |
| 1jg0 | DDT | Thymidylate synthase | / | 0.456 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.456 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 2fto | TMP | Thymidylate synthase | / | 0.456 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.456 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.456 | |
| 3q0z | 23E | Genome polyprotein | 2.7.7.48 | 0.456 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.456 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 1o2e | ANN | Phospholipase A2 | 3.1.1.4 | 0.455 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.455 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 3phc | IM5 | Purine nucleoside phosphorylase | / | 0.455 | |
| 3pn1 | IVH | DNA ligase | / | 0.455 | |
| 3rim | TPP | Transketolase | 2.2.1.1 | 0.455 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4c2p | X8Z | Angiotensin-converting enzyme | 3.2.1 | 0.455 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.455 | |
| 4zgs | NAD | Putative D-lactate dehydrogenase | / | 0.455 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.455 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.454 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.454 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.454 | |
| 2qe5 | 617 | Polyprotein | / | 0.454 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.454 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.454 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.454 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.454 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.454 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.454 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.454 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 1n0u | SO1 | Elongation factor 2 | / | 0.453 | |
| 1ngs | TPP | Transketolase 1 | 2.2.1.1 | 0.453 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.453 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.453 | |
| 2iyp | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.453 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.453 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.453 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.453 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.452 | |
| 2bxq | IMN | Serum albumin | / | 0.452 | |
| 2cje | DUN | DUTPase | / | 0.452 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.452 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.452 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.452 | |
| 2w0w | LZS | Bifunctional protein GlmU | / | 0.452 | |
| 2y67 | N21 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.452 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.452 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 3fsu | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.452 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.452 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.452 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4lh7 | 1X8 | DNA ligase | / | 0.452 | |
| 4oxi | GAP | Enterobactin synthetase component F-related protein | / | 0.452 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 5jqg | GTP | Tubulin alpha-1B chain | / | 0.452 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.451 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.451 | |
| 2e83 | FMN | FMN-binding protein | / | 0.451 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.451 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2r59 | PH0 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.451 | |
| 2rir | NAP | Dipicolinate synthase subunit A | / | 0.451 | |
| 2xs4 | ALA_PHE_THR | Karilysin | 3.4.24 | 0.451 | |
| 3a6q | FMN | FMN-binding protein | / | 0.451 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.451 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.451 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 3tlc | 7MD | Microcin C7 self-immunity protein MccF | / | 0.451 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.451 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4e2x | TYD | Methyltransferase | / | 0.451 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.451 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.451 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.451 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.451 | |
| 1b4p | GPS | Glutathione S-transferase Mu 2 | / | 0.450 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.450 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.450 | |
| 1u2r | SO1 | Elongation factor 2 | / | 0.450 | |
| 1xuz | MMN | Capsule biosynthesis protein | / | 0.450 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.450 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.450 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.450 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2y66 | N04 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.450 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.450 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.450 | |
| 3v2b | AR6 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.450 | |
| 4xmx | BES | Aminopeptidase N | 3.4.11.2 | 0.450 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.449 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.449 | |
| 1qrt | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.449 | |
| 1tgv | 5UD | Uridine phosphorylase | 2.4.2.3 | 0.449 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.449 | |
| 2ay3 | MPP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.449 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.449 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.449 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.449 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.449 | |
| 2pid | YSA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.449 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.449 | |
| 3mfl | DHY | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.449 | |
| 3mfl | DHY | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.449 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.449 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.449 | |
| 4biw | ANP | Sensor histidine kinase CpxA | / | 0.449 | |
| 4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.449 | |
| 1b8o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.448 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1u4g | HPI | Elastase | 3.4.24.26 | 0.448 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.448 | |
| 2j4k | U5P | Uridylate kinase | 2.7.4.22 | 0.448 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.448 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.448 | |
| 2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.448 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.448 | |
| 3vv8 | B02 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4boe | CLR | Japanin | / | 0.448 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.448 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.448 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.448 | |
| 1ef9 | 2CP | Methylmalonyl-CoA decarboxylase | 4.1.1.41 | 0.447 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.447 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.447 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.447 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.447 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.447 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.447 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.447 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.447 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.447 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.447 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.447 | |
| 3nuv | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.447 | |
| 3p5p | A3C | Taxadiene synthase | 4.2.3.17 | 0.447 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.447 | |
| 3qdq | COA | 4-Hydroxybutyrate CoA-transferase | / | 0.447 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.447 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.447 | |
| 4bew | ACP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.447 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 4kc1 | WS1 | Histo-blood group ABO system transferase | / | 0.447 | |
| 4nmc | FAD | Bifunctional protein PutA | / | 0.447 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.447 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 1l5r | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.446 | |
| 1pf7 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.446 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.446 | |
| 2f6r | ACO | Bifunctional coenzyme A synthase | / | 0.446 | |
| 2jnp | NGH | Stromelysin-1 | 3.4.24.17 | 0.446 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.446 | |
| 3b9l | AZZ | Serum albumin | / | 0.446 | |
| 3c3e | FO1 | 2-phospho-L-lactate transferase | / | 0.446 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.446 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.446 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.446 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.446 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 4dld | TZG | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 4e2b | FMN | Dehydrogenase | / | 0.446 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.446 | |
| 4k5o | 1OT | M1 family aminopeptidase | 3.4.11 | 0.446 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.446 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.445 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.445 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1qm5 | PLP | Maltodextrin phosphorylase | 2.4.1.1 | 0.445 | |
| 1qru | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.445 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.445 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.445 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.445 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.445 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.445 | |
| 2h23 | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.445 | |
| 2v95 | HCY | Corticosteroid-binding globulin | / | 0.445 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.445 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 3rdq | DTB | Streptavidin | / | 0.445 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 3vo8 | GDP | Cell division protein FtsZ | / | 0.445 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.445 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.445 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.445 | |
| 4kc4 | WS3 | Histo-blood group ABO system transferase | / | 0.445 | |
| 4mk8 | 28Q | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 4o4l | GTP | Tubulin alpha-1B chain | / | 0.445 | |
| 4oi4 | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.445 | |
| 4r39 | ANP | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.445 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
| 5ebu | FMN | Lactate oxidase | / | 0.445 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 1f28 | UMP | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.444 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.444 | |
| 1rp4 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.444 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.444 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.444 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.444 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.444 | |
| 3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.444 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3fx4 | FX4 | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.444 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.444 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.444 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.444 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.444 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.444 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.444 | |
| 4y6n | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.444 | |
| 4z9r | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.444 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.443 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.443 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1t32 | OHH | Cathepsin G | 3.4.21.20 | 0.443 | |
| 1vyq | DUX | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.443 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2az3 | CDP | Nucleoside diphosphate kinase | / | 0.443 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.443 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.443 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.443 | |
| 2xb8 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.443 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.443 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.443 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3e39 | FMN | Nitroreductase | / | 0.443 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.443 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 3m6r | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.443 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.443 | |
| 3qen | 5BT | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4c9w | VGH | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.443 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 4o4i | GTP | Tubulin alpha-1B chain | / | 0.443 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 4tv9 | GTP | Tubulin alpha-1B chain | / | 0.443 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4ykf | NAI | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.443 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.442 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.442 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.442 | |
| 2dg3 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2gzl | 2AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.442 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.442 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.442 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.442 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.442 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 3ivx | FG6 | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.442 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.442 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3vgn | FNN | Steroid Delta-isomerase | 5.3.3.1 | 0.442 | |
| 3zrc | L8B | Von Hippel-Lindau disease tumor suppressor | / | 0.442 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.442 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.442 | |
| 4dz2 | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.442 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4mry | CEI | Obelin | / | 0.442 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.442 | |
| 4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.442 | |
| 5c8d | 5AD | Probable transcriptional regulator | / | 0.442 | |
| 5fsi | 8DG | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.442 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.441 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.441 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.441 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.441 | |
| 1qxo | FMN | Chorismate synthase | / | 0.441 | |
| 1rx4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1sze | 173 | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.441 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.441 | |
| 2b0q | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.441 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.441 | |
| 2h8x | FMN | XenA | / | 0.441 | |
| 2jfh | LK1 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 2vo4 | GTB | 2,4-D inducible glutathione S-transferase | / | 0.441 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.441 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.441 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.441 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.441 | |
| 3ndj | JHZ | Methyltransferase | / | 0.441 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.441 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.441 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.441 | |
| 3v1u | HXC | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.441 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.441 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.441 | |
| 3zw9 | T1G | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.441 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.441 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4ge5 | A89 | Tyrosine-protein phosphatase non-receptor type 9 | 3.1.3.48 | 0.441 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.441 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.441 | |
| 4pgh | SAM | Caffeic acid O-methyltransferase | / | 0.441 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.441 | |
| 4ug5 | XFK | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.441 | |
| 4v0s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.441 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.441 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.441 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.441 | |
| 5c4n | NAP | Precorrin-6A reductase | 1.3.1.54 | 0.441 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.441 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.441 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.440 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.440 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 1q3a | NGH | Stromelysin-2 | 3.4.24.22 | 0.440 | |
| 1x1r | GDP | Ras-related protein M-Ras | / | 0.440 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2fah | GDP | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | 4.1.1.32 | 0.440 | |
| 2i47 | KGY | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.440 | |
| 2qhw | PZZ | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.440 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.440 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 3lm1 | LEC | Agglutinin alpha chain | / | 0.440 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.440 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 3pfh | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.440 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.440 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.440 | |
| 3tza | TZG | Glutamate receptor 2 | / | 0.440 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.440 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.440 | |
| 4qxr | 1YE | Stimulator of interferon genes protein | / | 0.440 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.440 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | / | 0.440 | |
| 4ytn | FD8 | Succinate dehydrogenase cytochrome b560 | / | 0.440 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.440 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.440 |