sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1h62 | ANB | Pentaerythritol tetranitrate reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 1.000 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.637 | |
| 1gvr | TNL | Pentaerythritol tetranitrate reductase | / | 0.609 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.605 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.575 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.560 | |
| 3kft | NAD | Pentaerythritol tetranitrate reductase | / | 0.510 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.509 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.505 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.500 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.499 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.496 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.494 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.493 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.493 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.491 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.490 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.490 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.489 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.488 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.487 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.487 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.487 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.486 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.485 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.484 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.484 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.484 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.483 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.483 | |
| 3ge6 | FMN | Nitroreductase | / | 0.483 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.481 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.481 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.481 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.480 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.479 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.479 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.479 | |
| 3e8x | NAP | BH1520 protein | / | 0.479 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.479 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.479 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.478 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.477 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.477 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.477 | |
| 4z38 | FMN | MlnA | / | 0.477 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.476 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.476 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.476 | |
| 2xvu | 9DN | Serum albumin | / | 0.476 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.476 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.476 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.476 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.475 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.475 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.475 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.475 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.475 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.474 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.473 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.473 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.473 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.473 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.472 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.472 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.472 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.472 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.472 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.472 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.471 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.471 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.471 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.470 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.470 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.470 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.470 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.470 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.470 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.470 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.469 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.469 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.469 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.469 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.469 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.469 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.469 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.469 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.469 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.468 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.468 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.468 | |
| 3v2u | ATP | Protein GAL3 | / | 0.468 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.467 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.467 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.467 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.467 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.467 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.467 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.466 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.466 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.466 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.466 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.466 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.466 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.466 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.465 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.465 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.465 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.465 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.465 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.465 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.465 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.465 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.464 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.464 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.464 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.464 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.464 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.464 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.463 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.463 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.463 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.463 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.463 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.463 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.463 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.463 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.463 | |
| 4jic | FMN | GTN Reductase | / | 0.463 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.462 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.462 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.462 | |
| 1tu8 | GTX | Glutathione S-transferase 2 | 2.5.1.18 | 0.462 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.462 | |
| 2qs4 | LY5 | Glutamate receptor ionotropic, kainate 1 | / | 0.462 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.462 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.462 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.462 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.462 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.461 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.461 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.461 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.461 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.461 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.461 | |
| 3tba | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.461 | |
| 3wt0 | ATP | Cell division protein FtsA | / | 0.461 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.461 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.461 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.461 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.461 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.460 | |
| 3b9l | AZZ | Serum albumin | / | 0.460 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.460 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.460 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.460 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.460 | |
| 4u7w | NDP | MxaA | / | 0.460 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.460 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.459 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.459 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.459 | |
| 3fvl | BHK | Carboxypeptidase A1 | 3.4.17.1 | 0.459 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.459 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.459 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.459 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.459 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.458 | |
| 1l7x | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.458 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.458 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.458 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.458 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.458 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.458 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.458 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.458 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.458 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.458 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 4cfb | OM3 | Integrase | / | 0.458 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.458 | |
| 4tlz | FAD | KtzI | / | 0.458 | |
| 4to0 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.458 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 5ebu | FMN | Lactate oxidase | / | 0.458 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.457 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.457 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.457 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.457 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.457 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.457 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.457 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.457 | |
| 3x2e | NAI | Adenosylhomocysteinase | / | 0.457 | |
| 4c4o | NAD | SADH | / | 0.457 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.457 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.457 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.457 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.457 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.457 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.457 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.456 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.456 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.456 | |
| 1nl4 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.456 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.456 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.456 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.456 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.456 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.456 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.456 | |
| 4e2b | FMN | Dehydrogenase | / | 0.456 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.456 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.456 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.455 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.455 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.455 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.455 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.455 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.455 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.455 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.455 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.455 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.455 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.455 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.455 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.454 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.454 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.454 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.454 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.454 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.454 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.454 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.454 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.454 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.454 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.454 | |
| 4cfa | WOP | Integrase | / | 0.454 | |
| 4e2d | FMN | Dehydrogenase | / | 0.454 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.453 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.453 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 2dsg | SAH | Diphthine synthase | / | 0.453 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.453 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.453 | |
| 3frk | TQP | QdtB | / | 0.453 | |
| 3rqq | BA3 | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.453 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.453 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.453 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.453 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.453 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.453 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.453 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.453 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.453 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.452 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.452 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.452 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.452 | |
| 1pl1 | ABY | Glutathione S-transferase A1 | 2.5.1.18 | 0.452 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.452 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.452 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.452 | |
| 2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.452 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.452 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.452 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 3p3c | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.452 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.452 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.452 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.452 | |
| 4u0m | ATP | Cyclic GMP-AMP synthase | / | 0.452 | |
| 1dnp | MHF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.451 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.451 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.451 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.451 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.451 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.451 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.451 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.451 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.451 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.451 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.451 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.451 | |
| 4ohw | ATP | Protein clpf-1 | / | 0.451 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.451 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 1fml | RTL | Retinol dehydratase | / | 0.450 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.450 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 1ppj | ANY | Cytochrome b | / | 0.450 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.450 | |
| 1wua | AP8 | Actin, alpha skeletal muscle | / | 0.450 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.450 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.450 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2owk | SAH | Diphthine synthase | / | 0.450 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.450 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.450 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.450 | |
| 4tm3 | FAD | KtzI | / | 0.450 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.450 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1bp6 | UMP | Thymidylate synthase | / | 0.449 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.449 | |
| 1g7v | PAI | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.449 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1pz0 | NAP | Protein IolS | 1.1.1 | 0.449 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.449 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.449 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.449 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.449 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.449 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.449 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.449 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.449 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.449 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.449 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.449 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.449 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.448 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.448 | |
| 1jq5 | NAD | Glycerol dehydrogenase | 1.1.1.6 | 0.448 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.448 | |
| 1jum | BER | HTH-type transcriptional regulator QacR | / | 0.448 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.448 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.448 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.448 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2hut | SAH | Diphthine synthase | / | 0.448 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.448 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.448 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.448 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.448 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.448 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.448 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.447 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.447 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.447 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.447 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.447 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.447 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.447 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.447 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.447 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.447 | |
| 3a3g | DLZ | Lumazine protein | / | 0.447 | |
| 3abx | RCB | Glucanase | / | 0.447 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.447 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.447 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.447 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.447 | |
| 4lut | DCS | Alanine racemase | / | 0.447 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.447 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.447 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.446 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 1xvt | COA | L-carnitine CoA-transferase | / | 0.446 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.446 | |
| 2ibz | UQ6 | Cytochrome b | / | 0.446 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.446 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.446 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 3sop | GDP | Neuronal-specific septin-3 | / | 0.446 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.446 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.446 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.446 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4o67 | 1SY | Cyclic GMP-AMP synthase | / | 0.446 | |
| 4uoc | NCN | CinA-like protein | / | 0.446 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.446 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.445 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.445 | |
| 2bkj | FMN | NADPH-flavin oxidoreductase | / | 0.445 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.445 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.445 | |
| 2r59 | PH0 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.445 | |
| 2yqz | SAM | Uncharacterized protein | / | 0.445 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.445 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3u9e | COA | Lmo1369 protein | / | 0.445 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.445 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.445 | |
| 4kl1 | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.445 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.445 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.445 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.445 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.445 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 1kqc | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.444 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.444 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.444 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.444 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.444 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.444 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.444 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.444 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.444 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.444 | |
| 2x96 | RX3 | Angiotensin-converting enzyme | 3.4.15.1 | 0.444 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.444 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.444 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.444 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.444 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.444 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.444 | |
| 4ck2 | NVU | Integrase | / | 0.444 | |
| 4jxr | ACO | Acetyltransferase | / | 0.444 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.444 | |
| 4xr9 | NAD | CalS8 | / | 0.444 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.444 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.444 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1g6o | ADP | Cag alpha | / | 0.443 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.443 | |
| 1m2o | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.443 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 1vf3 | GDN | Glutathione S-transferase 3 | 2.5.1.18 | 0.443 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.443 | |
| 2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.443 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.443 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.443 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.443 | |
| 2xvv | 9DN | Serum albumin | / | 0.443 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.443 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.443 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.443 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.443 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.443 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.443 | |
| 4hms | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.443 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.443 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.443 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.443 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.443 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.443 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.443 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.443 | |
| 5dg3 | U21 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase | / | 0.443 | |
| 1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.442 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.442 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.442 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.442 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.442 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.442 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.442 | |
| 2e17 | SAH | Diphthine synthase | / | 0.442 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.442 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.442 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.442 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.442 | |
| 2x90 | EAL | Angiotensin-converting enzyme | 3.4.15.1 | 0.442 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.442 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.442 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3e6e | DCS | Alanine racemase | / | 0.442 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.442 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.442 | |
| 3n0c | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.442 | |
| 3qw4 | U5P | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | / | 0.442 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.442 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.442 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 4h0x | NAD | Iota toxin component Ia | / | 0.442 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.442 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.442 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.441 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.441 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.441 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.441 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.441 | |
| 2iyp | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.441 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.441 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.441 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.441 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.441 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.441 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.441 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.441 | |
| 2xy9 | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.441 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.441 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.441 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.441 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.441 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.441 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.441 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4cgd | 8P3 | Integrase | / | 0.441 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.441 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.441 | |
| 4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.441 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.441 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.441 | |
| 4x81 | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.440 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.440 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.440 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.440 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.440 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.440 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.440 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.440 | |
| 2emr | SAH | Diphthine synthase | / | 0.440 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.440 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2ohv | NHL | Glutamate racemase | / | 0.440 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.440 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.440 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.440 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.440 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.440 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.440 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.440 | |
| 3iog | SDF | Metallo-beta-lactamase type 2 | / | 0.440 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.440 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.440 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.440 | |
| 4die | C5P | Cytidylate kinase | / | 0.440 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.440 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.440 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.440 |