sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2m3z | 1HF | Gag-Pol polyprotein |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2m3z | 1HF | Gag-Pol polyprotein | / | 1.000 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.515 | |
| 2ejz | SAH | Diphthine synthase | / | 0.510 | |
| 3bld | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.510 | |
| 1dgg | NDP | Catalase | 1.11.1.6 | 0.504 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.502 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.498 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.496 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.496 | |
| 4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.495 | |
| 4uof | DAT | Nucleoside diphosphate kinase | / | 0.494 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.493 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.492 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.491 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.490 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.488 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.487 | |
| 4b6s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.487 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.485 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.485 | |
| 2clf | F6F | Tryptophan synthase alpha chain | / | 0.484 | |
| 3csj | CBL | Glutathione S-transferase P | 2.5.1.18 | 0.484 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.484 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.484 | |
| 2c3o | TPP | Pyruvate synthase | / | 0.483 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.483 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.482 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.482 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.482 | |
| 2vez | ACO | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.481 | |
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.481 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.481 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.479 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.479 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.479 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.478 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.478 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 2w5b | AGS | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.477 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.477 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.476 | |
| 2z4w | 749 | Geranylgeranyl pyrophosphate synthase | / | 0.476 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.476 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.476 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.475 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.475 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.475 | |
| 3eku | CY9 | Actin-5C | / | 0.475 | |
| 3gus | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.475 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.475 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.474 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.474 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.474 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.474 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.473 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.473 | |
| 3glu | LYS_VAL_MET | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.473 | |
| 3lth | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.473 | |
| 4h6u | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.473 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
| 5doz | NDP | JamJ | / | 0.473 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.472 | |
| 2lbd | REA | Retinoic acid receptor gamma | / | 0.472 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.472 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.472 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.472 | |
| 2vxk | COA | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.472 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.472 | |
| 3qzy | FAD | FAD-linked sulfhydryl oxidase | / | 0.472 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.472 | |
| 4lwx | MU2 | Ribosome inactivating protein | / | 0.472 | |
| 4qii | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.472 | |
| 4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.472 | |
| 4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.472 | |
| 1bx9 | GLY_GGL_FOE | Glutathione S-transferase F2 | 2.5.1.18 | 0.471 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.471 | |
| 3b03 | VNR | Isopentenyl-diphosphate delta-isomerase | / | 0.471 | |
| 3c1o | NAP | Eugenol synthase | / | 0.471 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.471 | |
| 3l2k | PXC | EhpF | / | 0.471 | |
| 3n9j | EAA | Glutathione S-transferase P | 2.5.1.18 | 0.471 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.471 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.471 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.471 | |
| 4oma | LCS | Methionine gamma-lyase | / | 0.471 | |
| 1fml | RTL | Retinol dehydratase | / | 0.470 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.470 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.470 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.470 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.470 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.470 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.470 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.470 | |
| 3g11 | P9C | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.470 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.470 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.470 | |
| 4uz6 | SCR | Palmitoleoyl-protein carboxylesterase NOTUM | / | 0.470 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.469 | |
| 1zpr | CB3 | Thymidylate synthase | / | 0.469 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.469 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.469 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.469 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.469 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.468 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.468 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.468 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.468 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.468 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.467 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.467 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.467 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.467 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.467 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.467 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.467 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.466 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.466 | |
| 1kf6 | HQO | Fumarate reductase iron-sulfur subunit | 1.3.5.1 | 0.466 | |
| 1kf6 | HQO | Fumarate reductase subunit C | / | 0.466 | |
| 1kf6 | HQO | Fumarate reductase subunit D | / | 0.466 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.466 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.466 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.466 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.466 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.466 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.466 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.466 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.466 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.466 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.466 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.465 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.465 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.465 | |
| 1typ | NAP | Trypanothione reductase | 1.8.1.12 | 0.465 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.465 | |
| 2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.465 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.465 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.465 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.465 | |
| 4cry | ACO | PanD regulatory factor | / | 0.465 | |
| 4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.465 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.465 | |
| 4y6u | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.465 | |
| 5bsr | COA | 4-coumarate--CoA ligase 2 | 6.2.1.12 | 0.465 | |
| 5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.465 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.465 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.464 | |
| 1k9s | FM2 | Purine nucleoside phosphorylase DeoD-type | / | 0.464 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.464 | |
| 1maq | PGU | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.464 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.464 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 2xnm | WGZ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.464 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.464 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.464 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.464 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.464 | |
| 1f3e | DPZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.463 | |
| 2clm | F6F | Tryptophan synthase alpha chain | / | 0.463 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.463 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.463 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.463 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.463 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.463 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.463 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.463 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.463 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.462 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.462 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.462 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.462 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.462 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.462 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.462 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.462 | |
| 4jey | PLP | Acetylornithine/succinyldiaminopimelate aminotransferase | 2.6.1.11 | 0.462 | |
| 4jv4 | 1OR | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.462 | |
| 5dp2 | NAP | CurF | / | 0.462 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.462 | |
| 1fm1 | WAY | Collagenase 3 | 3.4.24 | 0.461 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1kuy | COT | Serotonin N-acetyltransferase | / | 0.461 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.461 | |
| 3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.461 | |
| 3ghh | 2NF | CD38 molecule | / | 0.461 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.461 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.461 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.461 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.461 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.461 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 4qij | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.461 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.460 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.460 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.460 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.460 | |
| 2bo8 | GDX | Mannosylglycerate synthase | / | 0.460 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.460 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.460 | |
| 2pnu | ENM | Androgen receptor | / | 0.460 | |
| 3kxo | KXO | Hematopoietic prostaglandin D synthase | / | 0.460 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.460 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.460 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.460 | |
| 4hsh | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.460 | |
| 4mrx | CZH | Obelin | / | 0.460 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.459 | |
| 1l0c | COT | Serotonin N-acetyltransferase | / | 0.459 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.459 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.459 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.459 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.459 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.459 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.459 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.459 | |
| 3vi5 | M4M | Hematopoietic prostaglandin D synthase | / | 0.459 | |
| 4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.459 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.459 | |
| 4zth | GG5 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.459 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.458 | |
| 1lrm | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.458 | |
| 1syn | F89 | Thymidylate synthase | / | 0.458 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.458 | |
| 2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.458 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.458 | |
| 2y6d | TQJ | Matrilysin | 3.4.24.23 | 0.458 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.458 | |
| 3n76 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.458 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.458 | |
| 3x03 | ANP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.458 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.458 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.458 | |
| 4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.458 | |
| 4gqk | ADP | Actin cross-linking toxin VgrG1 | / | 0.458 | |
| 4h7z | GUN | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.458 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.458 | |
| 4z87 | GDP | Inosine-5'-monophosphate dehydrogenase | / | 0.458 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.458 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.457 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.457 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.457 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.457 | |
| 4ag9 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.457 | |
| 4l17 | DNQ | Glutamate receptor 2 | / | 0.457 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.457 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.457 | |
| 4py0 | 6AT | P2Y purinoceptor 12 | / | 0.457 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.456 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.456 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.456 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.456 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.456 | |
| 2h4k | 509 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.456 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.456 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.456 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.456 | |
| 3e6e | DCS | Alanine racemase | / | 0.456 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.456 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.456 | |
| 4jva | 1OR | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.456 | |
| 4phl | PIL | Phosphodiesterase | / | 0.456 | |
| 4y1b | NAP | AntE | / | 0.456 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.455 | |
| 1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.455 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.455 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.455 | |
| 1v48 | HA1 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 1vi0 | DCC | Fatty acid metabolism regulator protein | / | 0.455 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.455 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.455 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.455 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.455 | |
| 3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.455 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.455 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.455 | |
| 1aqx | GTD | Glutathione S-transferase P | 2.5.1.18 | 0.454 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.454 | |
| 2olc | ADP | Methylthioribose kinase | 2.7.1.100 | 0.454 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.454 | |
| 2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.454 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.454 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.454 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.454 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.454 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 3vc2 | SAH | Geranyl diphosphate 2-C-methyltransferase | 2.1.1.255 | 0.454 | |
| 4je5 | PLP | Aromatic/aminoadipate aminotransferase 1 | 2.6.1.39 | 0.454 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4r7u | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.454 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.453 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.453 | |
| 1uys | H1L | Acetyl-CoA carboxylase | / | 0.453 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.453 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.453 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.453 | |
| 2oad | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.453 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.453 | |
| 3f6s | FMN | Flavodoxin | / | 0.453 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3up0 | D7S | aceDAF-12 | / | 0.453 | |
| 4dm8 | REA | Retinoic acid receptor beta | / | 0.453 | |
| 4uxq | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.453 | |
| 1xa4 | COA | L-carnitine CoA-transferase | / | 0.452 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.452 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.452 | |
| 2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.452 | |
| 2wpw | ACO | Orf14 | / | 0.452 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.452 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.452 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.452 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.452 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.452 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.452 | |
| 4dya | 0MF | Nucleoprotein | / | 0.452 | |
| 4iah | 1DX | Alr2278 protein | / | 0.452 | |
| 4pl9 | ADP | Ethylene receptor 1 | / | 0.452 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.452 | |
| 1exa | 394 | Retinoic acid receptor gamma | / | 0.451 | |
| 1qv0 | CZH | Obelin | / | 0.451 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.451 | |
| 1tsd | F89 | Thymidylate synthase | / | 0.451 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 2f59 | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | / | 0.451 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.451 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.451 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.451 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.451 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.451 | |
| 4x24 | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.451 | |
| 4y9x | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.451 | |
| 1muu | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.450 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
| 1r2j | FAD | FkbI | / | 0.450 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.450 | |
| 1x27 | ASP_ASP_TYR_VAL_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.450 | |
| 1y6q | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.450 | |
| 2imk | GTX | AGAP009194-PA | / | 0.450 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.450 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.450 | |
| 2q2z | ADP | Kinesin-like protein KIF11 | / | 0.450 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.450 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.450 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 3pch | CHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.450 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.450 | |
| 4bqy | FNT | Egl nine homolog 1 | / | 0.450 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.450 | |
| 4pxz | CLR | P2Y purinoceptor 12 | / | 0.450 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 1aqv | 0HG | Glutathione S-transferase P | 2.5.1.18 | 0.449 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.449 | |
| 1ifx | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.449 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.449 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.449 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.449 | |
| 2yis | I46 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.449 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.449 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.449 | |
| 4f9y | GG5 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.449 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 4pyo | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.449 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.449 | |
| 1bmf | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.448 | |
| 1bmf | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.448 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.448 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.448 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1rxj | BNI | Streptavidin | / | 0.448 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.448 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 1y6r | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.448 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.448 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.448 | |
| 2jav | 5Z5 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.448 | |
| 2zym | ACX | Periplasmic binding protein | / | 0.448 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.448 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.448 | |
| 3x06 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.448 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.448 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.448 | |
| 1euy | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.447 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.447 | |
| 1xuz | MMN | Capsule biosynthesis protein | / | 0.447 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.447 | |
| 2ew5 | Y12 | Peptide deformylase | / | 0.447 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.447 | |
| 2x2r | ADP | Kinesin-like protein KIF11 | / | 0.447 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.447 | |
| 3a26 | MTA | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.447 | |
| 3anm | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.447 | |
| 3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.447 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.447 | |
| 3zs5 | SB2 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.447 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.447 | |
| 5ilw | URI | Ribosome inactivating protein | / | 0.447 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.447 | |
| 1el4 | CTZ | Obelin | / | 0.446 | |
| 1jxz | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.446 | |
| 1p4a | PCP | Pur operon repressor | / | 0.446 | |
| 1pu9 | COA | HAT A1 | / | 0.446 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.446 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.446 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.446 | |
| 2wks | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.446 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.446 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.446 | |
| 3bhr | THG | Thymidylate synthase | / | 0.446 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.446 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.446 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3k3i | I46 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.446 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4az3 | S35 | Lysosomal protective protein | 3.4.16.5 | 0.446 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.446 | |
| 4hej | 14D | Thymidylate kinase | / | 0.446 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.446 | |
| 4uoh | ADP | Nucleoside diphosphate kinase | / | 0.446 | |
| 5jad | FB2 | Platelet-activating factor acetylhydrolase | 3.1.1.47 | 0.446 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.445 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 1nc1 | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.445 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.445 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 1tlc | F89 | Thymidylate synthase | / | 0.445 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.445 | |
| 1ybg | TAV | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.445 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 2p15 | EZT | Estrogen receptor | / | 0.445 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.445 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.445 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.445 | |
| 2x21 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.445 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.445 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.445 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.445 | |
| 3hll | I46 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3ll9 | ADP | Isopentenyl phosphate kinase | / | 0.445 | |
| 4b6r | 3DQ | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.445 | |
| 4kg1 | PCG | Diguanylate cyclase | / | 0.445 | |
| 4l0o | PLP | Cystathionine gamma-synthase | 2.5.1.48 | 0.445 | |
| 4mfp | COA | Uncharacterized protein | / | 0.445 | |
| 5epo | TUD | 7-alpha-hydroxysteroid deydrogenase | / | 0.445 | |
| 1b8o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 1d8f | SPI | Stromelysin-1 | 3.4.24.17 | 0.444 | |
| 1dp2 | LPB | Thiosulfate sulfurtransferase | / | 0.444 | |
| 1hy3 | PPS | Estrogen sulfotransferase | 2.8.2.4 | 0.444 | |
| 1jf2 | CZH | Obelin | / | 0.444 | |
| 1ne4 | RP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.444 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.444 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.444 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.444 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.444 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2w0h | NDP | Trypanothione reductase | / | 0.444 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.444 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.444 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.444 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.444 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.444 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.444 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.444 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.444 | |
| 5c8d | 5AD | Probable transcriptional regulator | / | 0.444 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.443 | |
| 1e1l | NAP | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.443 | |
| 1ee1 | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.443 | |
| 1i05 | LTL | Major urinary protein 6 | / | 0.443 | |
| 1l0l | FMX | Cytochrome b | / | 0.443 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1yrs | ADP | Kinesin-like protein KIF11 | / | 0.443 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.443 | |
| 2bju | IH4 | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 2ewp | TXF | Estrogen-related receptor gamma | / | 0.443 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.443 | |
| 2jbl | SMA | Reaction center protein L chain | / | 0.443 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3gts | D3M | DdmC | / | 0.443 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.443 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.443 | |
| 3rno | NAP | NAD(P)H-hydrate epimerase | 5.1.99.6 | 0.443 | |
| 3v4f | GNP | GTPase HRas | / | 0.443 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.443 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4u95 | MIY | Multidrug efflux pump subunit AcrB | / | 0.443 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.443 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.443 | |
| 5kf9 | COA | Predicted acetyltransferase | / | 0.443 | |
| 1efz | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.442 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.442 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.442 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1q63 | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.442 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.442 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.442 | |
| 1zyd | ATP | eIF-2-alpha kinase GCN2 | / | 0.442 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.442 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.442 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.442 | |
| 2r6k | GTX | Glutathione S-transferase A1 | 2.5.1.18 | 0.442 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 2wpx | ACO | Orf14 | / | 0.442 | |
| 2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3gg2 | UGA | Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family | / | 0.442 | |
| 3hfb | ML4 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.442 | |
| 3hz6 | ADP | Xylulokinase | / | 0.442 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.442 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.442 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.442 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.442 | |
| 3zv6 | 4HB | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.442 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4aoa | IK2 | Beta-phenylalanine transaminase | 2.6.1 | 0.442 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4nbj | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.442 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.442 | |
| 5jdz | SAH | Methyl transferase | / | 0.442 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.442 | |
| 1gaq | FAD | Ferredoxin | / | 0.441 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.441 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 1k8z | IAG | Tryptophan synthase alpha chain | / | 0.441 | |
| 1s36 | CEI | Obelin | / | 0.441 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.441 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.441 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.441 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.441 | |
| 2lbv | EB4 | Extracellular fatty acid-binding protein | / | 0.441 | |
| 2mm3 | CHO | Gastrotropin | / | 0.441 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.441 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.441 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.441 | |
| 3bbf | GDP | Nucleoside diphosphate kinase B | 2.7.4.6 | 0.441 | |
| 3dko | IHZ | Ephrin type-A receptor 7 | 2.7.10.1 | 0.441 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.441 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.441 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 3rix | 923 | Luciferin 4-monooxygenase | 1.13.12.7 | 0.441 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.441 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.441 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.441 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.441 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.441 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 5cho | FAD | Flavin reductase | / | 0.441 | |
| 5kf8 | COA | Predicted acetyltransferase | / | 0.441 | |
| 5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1eir | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.440 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.440 | |
| 1kie | AD3 | IAG-nucleoside hydrolase | / | 0.440 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.440 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.440 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.440 | |
| 1q4w | DQU | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
| 1sqq | OST | Cytochrome b | / | 0.440 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.440 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.440 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2qe2 | 452 | Polyprotein | / | 0.440 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3gf4 | UPG | UDP-galactopyranose mutase | 5.4.99.9 | 0.440 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.440 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.440 | |
| 3x02 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.440 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.440 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.440 | |
| 4boe | CLR | Japanin | / | 0.440 | |
| 4eh3 | IRG | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.440 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.440 | |
| 4hl5 | 15W | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.440 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.440 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.440 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.440 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.440 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 4tyj | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.440 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.440 | |
| 4xug | F9F | Tryptophan synthase alpha chain | / | 0.440 | |
| 4yp0 | 5IQ | Histidyl-tRNA synthetase, putative | / | 0.440 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 5je2 | SAH | Methyl transferase | / | 0.440 |