sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1e32 | ADP | Transitional endoplasmic reticulum ATPase | 3.6.4.6 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1e32 | ADP | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 1.000 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.506 | |
| 2ce7 | ADP | ATP-dependent zinc metalloprotease FtsH | / | 0.503 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.495 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.495 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.494 | |
| 1rc0 | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.492 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.492 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.489 | |
| 1cg3 | IMO | Adenylosuccinate synthetase | / | 0.487 | |
| 1s9p | DES | Estrogen-related receptor gamma | / | 0.487 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.487 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.486 | |
| 3zuy | TCH | Transporter | / | 0.486 | |
| 4l4x | NDP | AmphI | / | 0.486 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.485 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.485 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.485 | |
| 5a3b | APR | SIR2 family protein | / | 0.484 | |
| 5a3c | NAD | SIR2 family protein | / | 0.484 | |
| 3zux | TCH | Transporter | / | 0.483 | |
| 4ajp | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.483 | |
| 1rby | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.482 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.482 | |
| 4xf7 | ACP | Carbohydrate/pyrimidine kinase, PfkB family | / | 0.482 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.481 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.481 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.481 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.480 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.480 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.479 | |
| 4dwv | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.478 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.477 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.477 | |
| 2y5k | YCU | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.477 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.477 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 2gd6 | ACO | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.476 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.476 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.475 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.475 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.475 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.475 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 2cx8 | SAH | Ribosomal RNA small subunit methyltransferase E | / | 0.474 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.474 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.474 | |
| 4yv2 | S4M | Spermidine synthase, putative | / | 0.474 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.473 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.473 | |
| 2a4l | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.473 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.473 | |
| 2vo0 | M03 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.473 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.473 | |
| 3dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.473 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.473 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.473 | |
| 4oae | CLM | Uncharacterized protein | / | 0.473 | |
| 5cdt | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.473 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.472 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.472 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.472 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.471 | |
| 1rj9 | GCP | Signal recognition particle receptor FtsY | / | 0.471 | |
| 1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.471 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.471 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.471 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.471 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.471 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.471 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.471 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 4mle | VO1 | Glucokinase | 2.7.1.2 | 0.471 | |
| 5ce3 | ADP | Protein kinase YopO | / | 0.471 | |
| 1eu1 | MGD | Dimethyl sulfoxide/trimethylamine N-oxide reductase | / | 0.470 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.470 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.470 | |
| 2uw0 | GVK | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.470 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.470 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.470 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.470 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.470 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.469 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.469 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.468 | |
| 1me7 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.468 | |
| 1njs | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.468 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.468 | |
| 3kq7 | KQ7 | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 3n8n | N88 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.468 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.468 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.468 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.468 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.468 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.468 | |
| 4ww0 | ADP | ATP-dependent zinc metalloprotease FtsH | / | 0.468 | |
| 1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.467 | |
| 1qf5 | RPL | Adenylosuccinate synthetase | / | 0.467 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.467 | |
| 2cdu | FAD | NADH oxidase | / | 0.467 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.467 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.467 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.467 | |
| 3p4t | FAO | Putative acyl-CoA dehydrogenase | / | 0.467 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.467 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.467 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.467 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.467 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 1lon | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.466 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.466 | |
| 1osv | CHC | Bile acid receptor | / | 0.466 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.466 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.466 | |
| 2vo6 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.466 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.466 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.466 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.466 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.466 | |
| 1rbm | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.465 | |
| 1rbq | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.465 | |
| 2vq5 | LDP | S-norcoclaurine synthase | / | 0.465 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.465 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.465 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.465 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 4aic | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.465 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1 | / | 0.465 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1-binding protein 1 | / | 0.465 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.465 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.465 | |
| 4nyw | 2O3 | CREB-binding protein | / | 0.465 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.465 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.464 | |
| 1het | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.464 | |
| 1kgj | FL8 | Transthyretin | / | 0.464 | |
| 1xny | BTN | Propionyl-CoA carboxylase complex B subunit | / | 0.464 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.464 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.464 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.464 | |
| 3bhl | THG | Thymidylate synthase | / | 0.464 | |
| 3d72 | FAD | Vivid PAS protein VVD | / | 0.464 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 5ikq | JMS | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.464 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.464 | |
| 5kje | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.464 | |
| 1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.463 | |
| 1cg1 | IMO | Adenylosuccinate synthetase | / | 0.463 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.463 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.463 | |
| 2fze | APR | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.463 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.463 | |
| 3wg6 | NDP | NADPH-dependent conjugated polyketone reductase C1 | / | 0.463 | |
| 5mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.463 | |
| 1c3e | NHR | Phosphoribosylglycinamide formyltransferase | / | 0.462 | |
| 1nv8 | SAM | Release factor glutamine methyltransferase | 2.1.1.297 | 0.462 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.462 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.462 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.462 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.462 | |
| 2wo9 | 068 | Macrophage metalloelastase | 3.4.24.65 | 0.462 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.462 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.462 | |
| 4an2 | EUI | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.462 | |
| 4gc9 | SAM | Dimethyladenosine transferase 1, mitochondrial | 2.1.1 | 0.462 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.462 | |
| 4inb | 1F6 | Gag protein | / | 0.462 | |
| 4xye | NAD | Formate dehydrogenase | / | 0.462 | |
| 1biw | S80 | Stromelysin-1 | 3.4.24.17 | 0.461 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.461 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.461 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.461 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.461 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.461 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.461 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.461 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.461 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.461 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 4gah | 0ET | Acyl-coenzyme A thioesterase THEM4 | 3.1.2.2 | 0.461 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.461 | |
| 4l2i | FAD | Electron transfer flavoprotein alpha/beta-subunit | / | 0.461 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.461 | |
| 4olf | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.461 | |
| 1qvn | FRI | Interleukin-2 | / | 0.460 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1xny | 191 | Propionyl-CoA carboxylase complex B subunit | / | 0.460 | |
| 2bwg | 5GP | GMP reductase 1 | / | 0.460 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.460 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.460 | |
| 2ibw | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.460 | |
| 2ic3 | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 2rir | NAP | Dipicolinate synthase subunit A | / | 0.460 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.460 | |
| 4bwx | AGS | PAB-dependent poly(A)-specific ribonuclease subunit pan3 | / | 0.460 | |
| 4kub | COA | Uncharacterized protein | / | 0.460 | |
| 1bob | ACO | Histone acetyltransferase type B catalytic subunit | / | 0.459 | |
| 1c2t | NHS | Phosphoribosylglycinamide formyltransferase | / | 0.459 | |
| 1llu | NAD | Alcohol dehydrogenase | / | 0.459 | |
| 1oit | HDT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.459 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.459 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.459 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.459 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.459 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.459 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.459 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.459 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.459 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.459 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.459 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.459 | |
| 4hxy | NDP | Plm1 | / | 0.459 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.459 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.458 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.458 | |
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.458 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.458 | |
| 1yre | COA | Uncharacterized protein | / | 0.458 | |
| 2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.458 | |
| 3qs8 | 17D | Anthranilate phosphoribosyltransferase | / | 0.458 | |
| 3rhh | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.458 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.458 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.458 | |
| 1cde | DZF | Phosphoribosylglycinamide formyltransferase | / | 0.457 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.457 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.457 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.457 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.457 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.457 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.457 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 2owk | SAH | Diphthine synthase | / | 0.457 | |
| 2vn9 | GVD | Calcium/calmodulin-dependent protein kinase type II subunit delta | 2.7.11.17 | 0.457 | |
| 2vyv | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.457 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.457 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3b20 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.457 | |
| 3n1s | 5GP | Purine nucleoside phosphoramidase | / | 0.457 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.457 | |
| 3vey | 0H5 | Glucokinase | 2.7.1.2 | 0.457 | |
| 4e5w | 0NT | Tyrosine-protein kinase JAK1 | / | 0.457 | |
| 4eu5 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.457 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.457 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.457 | |
| 4oze | 24G | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.457 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.457 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.457 | |
| 4ux9 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.457 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.457 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.457 | |
| 5doz | NDP | JamJ | / | 0.457 | |
| 5kj6 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.457 | |
| 1b3r | NAD | Adenosylhomocysteinase | 3.3.1.1 | 0.456 | |
| 1bqo | N25 | Stromelysin-1 | 3.4.24.17 | 0.456 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1i6x | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.456 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.456 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2p2x | SAH | Diphthine synthase | / | 0.456 | |
| 2p4j | 23I | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 2woa | 576 | Macrophage metalloelastase | 3.4.24.65 | 0.456 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.456 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 3elc | F01 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.456 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.456 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.456 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.456 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.456 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.456 | |
| 4nv1 | 4TG | Formyl transferase | / | 0.456 | |
| 4pd6 | URI | Nucleoside permease | / | 0.456 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.455 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.455 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.455 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.455 | |
| 1gyp | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.455 | |
| 1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.455 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.455 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.455 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.455 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2r26 | CMC | Citrate synthase | 2.3.3.16 | 0.455 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.455 | |
| 3awi | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | 1.5 | 0.455 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.455 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.455 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.455 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4a33 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4bqu | CLR | Japanin | / | 0.455 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.455 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.455 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.454 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.454 | |
| 1cg4 | IMO | Adenylosuccinate synthetase | / | 0.454 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.454 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1ksz | PGS | Adenylosuccinate synthetase | / | 0.454 | |
| 1sln | INH | Stromelysin-1 | 3.4.24.17 | 0.454 | |
| 1u3v | NAD | Alcohol dehydrogenase 1B | 1.1.1.1 | 0.454 | |
| 1yvf | PH7 | Polyprotein | / | 0.454 | |
| 2ar8 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.454 | |
| 2nu9 | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.454 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.454 | |
| 3rkb | 12Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4a8m | ATP | RNA-directed RNA polymerase | 2.7.7.48 | 0.454 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.454 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.454 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 4jal | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.454 | |
| 4nfh | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.454 | |
| 4pl4 | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.454 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.454 | |
| 5ahs | COA | Acyl-CoA dehydrogenase | / | 0.454 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.453 | |
| 1soz | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.453 | |
| 1tys | TMP | Thymidylate synthase | / | 0.453 | |
| 1uum | AFI | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.453 | |
| 1x15 | NAD | NAD(P) transhydrogenase subunit alpha | 1.6.1.2 | 0.453 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.453 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.453 | |
| 2ejj | SAH | Diphthine synthase | / | 0.453 | |
| 2gu8 | 796 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.453 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.453 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.453 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.453 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.453 | |
| 4qpm | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.453 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.453 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.453 | |
| 5cb5 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.453 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.452 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.452 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.452 | |
| 1um8 | ADP | ATP-dependent Clp protease ATP-binding subunit ClpX | / | 0.452 | |
| 2dbq | NAP | Glyoxylate reductase | 1.1.1.26 | 0.452 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.452 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.452 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.452 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.452 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 2ow0 | 6MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.452 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.452 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 3q7d | NPX | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.452 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3stx | BKA | Methylketone synthase I | / | 0.452 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.452 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
| 4dt9 | GMP | APH(2'')-Id | / | 0.452 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.452 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.452 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.452 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.452 | |
| 5ca1 | NZO | Tubulin beta-2 chain | / | 0.452 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.451 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 1mjh | ATP | Universal stress protein MJ0577 | / | 0.451 | |
| 1muu | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.451 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.451 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.451 | |
| 2bhi | SFT | Cytotoxin 3 | / | 0.451 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.451 | |
| 2dbz | NAP | Glyoxylate reductase | 1.1.1.26 | 0.451 | |
| 2ijg | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.451 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.451 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.451 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.451 | |
| 3i7i | 518 | Collagenase 3 | 3.4.24 | 0.451 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.451 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.451 | |
| 3vnt | 0JA | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.451 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.451 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.451 | |
| 4an3 | 5Y0 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.451 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.451 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.451 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.451 | |
| 4kwh | NAP | Reductase homolog | / | 0.451 | |
| 4lgh | 0JN | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.451 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.451 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.451 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.451 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.451 | |
| 5kj1 | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1dj3 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.450 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.450 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 1g38 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.450 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.450 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.450 | |
| 1nvm | NAD | Acetaldehyde dehydrogenase | 1.2.1.10 | 0.450 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.450 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.450 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.450 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.450 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2bxg | IBP | Serum albumin | / | 0.450 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.450 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.450 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.450 | |
| 2vto | LZ8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.450 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.450 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.450 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.450 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.450 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3pt6 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.450 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3tu5 | ATP | Actin, alpha skeletal muscle | / | 0.450 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.450 | |
| 3zxh | E41 | Collagenase 3 | 3.4.24 | 0.450 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.450 | |
| 4c4j | X21 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.450 | |
| 4cng | SAH | SpoU rRNA methylase | / | 0.450 | |
| 4d5g | FAD | Cyclohexane-1,2-dione hydrolase | 3.7.1.11 | 0.450 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.450 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.450 | |
| 4elh | 53I | Dihydrofolate reductase | / | 0.450 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.450 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 4umx | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.450 | |
| 4wlu | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.450 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.449 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 1cs4 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.449 | |
| 1g67 | TZP | Thiamine-phosphate synthase | / | 0.449 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.449 | |
| 1q8u | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.449 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.449 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.449 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.449 | |
| 1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 0.449 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.449 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.449 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.449 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.449 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.449 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.449 | |
| 3e8c | G96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.449 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3kec | 3KE | Collagenase 3 | 3.4.24 | 0.449 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.449 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.449 | |
| 4d7m | TDC | Tetracycline repressor protein class D | / | 0.449 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.449 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.449 | |
| 4e5k | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.449 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.449 | |
| 4l3j | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.449 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.449 | |
| 4loh | 1SY | Stimulator of interferon genes protein | / | 0.449 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.449 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.449 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.449 | |
| 4umy | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.449 | |
| 1cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.448 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.448 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.448 | |
| 1zpt | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.448 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2amt | 1AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.448 | |
| 2e20 | B4P | Propionate kinase | / | 0.448 | |
| 2jam | J60 | Calcium/calmodulin-dependent protein kinase type 1G | 2.7.11.17 | 0.448 | |
| 2oxt | SAM | Genome polyprotein | / | 0.448 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.448 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.448 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.448 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.448 | |
| 2w93 | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.448 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.448 | |
| 3bej | MUF | Bile acid receptor | / | 0.448 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.448 | |
| 3hji | FAD | Vivid PAS protein VVD | / | 0.448 | |
| 3i7g | 732 | Collagenase 3 | 3.4.24 | 0.448 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.448 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.448 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.448 | |
| 3r8l | Z30 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.448 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4a7b | 3W4 | Collagenase 3 | 3.4.24 | 0.448 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.448 | |
| 4asd | BAX | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.448 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4dja | FAD | (6-4) photolyase | / | 0.448 | |
| 4dwb | 0M7 | Farnesyl pyrophosphate synthase | / | 0.448 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.448 | |
| 4koy | CSC | Uncharacterized protein | / | 0.448 | |
| 4m10 | ICD | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.448 | |
| 4ng5 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 4r87 | COA | Spermidine N(1)-acetyltransferase | / | 0.448 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.448 | |
| 5f2k | SAH | Uncharacterized protein | / | 0.448 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.447 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.447 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.447 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.447 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 3cge | NDP | Coenzyme A disulfide reductase | / | 0.447 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.447 | |
| 3eks | CY9 | Actin-5C | / | 0.447 | |
| 3g8d | ADP | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.447 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4gap | NAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.447 | |
| 4kov | KOV | Uncharacterized protein | / | 0.447 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.447 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.447 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.447 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.447 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.447 | |
| 1cg0 | IMO | Adenylosuccinate synthetase | / | 0.446 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.446 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.446 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 alpha chain | / | 0.446 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 beta chain | / | 0.446 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.446 | |
| 1pzg | A3D | Lactate dehydrogenase | / | 0.446 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.446 | |
| 1xha | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.446 | |
| 2qn7 | HBZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.446 | |
| 2uw7 | GVP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3fws | ANP | Transcriptional repressor CcpN | / | 0.446 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.446 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.446 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.446 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.446 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.446 | |
| 3v1u | HXC | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.446 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.446 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.446 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.446 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.446 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.446 | |
| 4e6d | 0NU | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.446 | |
| 4j1p | 1K0 | Bromodomain-containing protein 2 | / | 0.446 | |
| 4kd1 | 1QK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.446 | |
| 4o0m | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.446 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.446 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.446 | |
| 8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1bmd | NAD | Malate dehydrogenase | / | 0.445 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.445 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.445 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.445 | |
| 1nf7 | RVP | Inosine-5'-monophosphate dehydrogenase 2 | / | 0.445 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.445 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1qmf | KEF | Penicillin-binding protein 2x | / | 0.445 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.445 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1tl3 | H20 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.445 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.445 | |
| 2f7z | 6EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2fhy | A37 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.445 | |
| 2gtm | LID | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.445 | |
| 2pd7 | FAD | Vivid PAS protein VVD | / | 0.445 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.445 | |
| 2rc6 | NAP | Ferredoxin--NADP reductase | / | 0.445 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.445 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.445 | |
| 3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.445 | |
| 3glu | LYS_VAL_MET | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.445 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3nie | ANP | Mitogen-activated protein kinase | / | 0.445 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4ajo | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.445 | |
| 4c59 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.445 | |
| 4ew3 | DXZ | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.445 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 4nxx | GDP | Mitochondrial dynamics protein MID51 | / | 0.445 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.445 | |
| 4s1h | ADP | Pyridoxal kinase, putative | / | 0.445 | |
| 4tm0 | NAP | KtzI | / | 0.445 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.445 | |
| 5kj1 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1caq | DPS | Stromelysin-1 | 3.4.24.17 | 0.444 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.444 | |
| 1nsy | ATP | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.444 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.444 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.444 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.444 | |
| 2dbr | NAP | Glyoxylate reductase | 1.1.1.26 | 0.444 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.444 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.444 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.444 | |
| 2rr1 | W8R | Genome polyprotein | / | 0.444 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.444 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.444 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.444 | |
| 3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.444 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.444 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.444 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.444 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.444 | |
| 3nwz | COA | BH2602 protein | / | 0.444 | |
| 3qql | X03 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.444 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
| 4fid | GDP | G protein alpha subunit, putative | / | 0.444 | |
| 4hia | FMN | LOV protein | / | 0.444 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.444 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.444 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.444 | |
| 5c3c | ADP | CbbQ/NirQ/NorQ domain protein | / | 0.444 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.443 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1ckp | PVB | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.443 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 1gqt | ACP | Ribokinase | / | 0.443 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.443 | |
| 1qan | SAH | rRNA adenine N-6-methyltransferase | 2.1.1.184 | 0.443 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.443 | |
| 1t2d | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 1um0 | FMN | Chorismate synthase | / | 0.443 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 1uyr | D1L | Acetyl-CoA carboxylase | / | 0.443 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.443 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2ga9 | AGS | Poly(A) polymerase catalytic subunit | 2.7.7.19 | 0.443 | |
| 2l8r | APR | O-acetyl-ADP-ribose deacetylase 1 | 3.5.1 | 0.443 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.443 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2xmy | CDK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.443 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.443 | |
| 3a6r | FMN | FMN-binding protein | / | 0.443 | |
| 3bhr | THG | Thymidylate synthase | / | 0.443 | |
| 3dei | RXB | Caspase-3 | 3.4.22.56 | 0.443 | |
| 3dfc | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3fgo | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.443 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.443 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 3owu | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.443 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.443 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.443 | |
| 3vev | 0H4 | Glucokinase | 2.7.1.2 | 0.443 | |
| 3wy0 | COA | Uncharacterized protein | / | 0.443 | |
| 3zok | NAD | 3-dehydroquinate synthase, chloroplastic | 4.2.3.4 | 0.443 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.443 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.443 | |
| 4ifn | 12O | Kelch-like ECH-associated protein 1 | / | 0.443 | |
| 4ih7 | 1ER | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.443 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.443 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.443 | |
| 4lsm | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 4oad | CLM | Uncharacterized protein | / | 0.443 | |
| 4yut | FMN | Family 3 adenylate cyclase | / | 0.443 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.443 | |
| 5l8l | ADP | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.442 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.442 | |
| 1got | GDP | Guanine nucleotide-binding protein G(t) subunit alpha-1 | / | 0.442 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1nht | PGS | Adenylosuccinate synthetase | / | 0.442 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.442 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2d52 | COA | 5,7-dihydroxy-2-methylchromone synthase | 2.3.1.216 | 0.442 | |
| 2g9u | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.442 | |
| 2gd2 | CAA | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.442 | |
| 2mse | GNP | MHC class I alpha chain | / | 0.442 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.442 | |
| 2oj9 | BMI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.442 | |
| 2oxw | ILE_ALA_GLY | Macrophage metalloelastase | 3.4.24.65 | 0.442 | |
| 2pci | SAH | Diphthine synthase | / | 0.442 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.442 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.442 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.442 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.442 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.442 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.442 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3kfm | KAI | Glutamate receptor 4 | / | 0.442 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.442 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.442 | |
| 3zmm | F9J | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.442 | |
| 4bcm | T7Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 4e5n | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.442 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.442 | |
| 4f9c | 0SX | Cell division cycle 7-related protein kinase | 2.7.11.1 | 0.442 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4iv0 | SAM | Phosphoethanolamine N-methyltransferase, putative | / | 0.442 | |
| 4tlz | NAP | KtzI | / | 0.442 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.442 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 4yus | FMN | Family 3 adenylate cyclase | / | 0.442 | |
| 4z87 | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.442 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.442 | |
| 5c1l | GDU | Histo-blood group ABO system transferase | / | 0.442 | |
| 5dmh | ADP | 3-oxo-tetronate kinase | / | 0.442 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.442 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 1d8m | BBH | Stromelysin-1 | 3.4.24.17 | 0.441 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.441 | |
| 1hld | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 1ky4 | NAD | Adenosylhomocysteinase | 3.3.1.1 | 0.441 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 1nav | IH5 | Thyroid hormone receptor alpha | / | 0.441 | |
| 1reo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.441 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.441 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 1v4s | MRK | Glucokinase | 2.7.1.2 | 0.441 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 2bhh | RYU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.441 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2fy5 | SOP | Choline O-acetyltransferase | 2.3.1.6 | 0.441 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 2w98 | P1Z | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 2wo8 | 077 | Macrophage metalloelastase | 3.4.24.65 | 0.441 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.441 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.441 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 3fpa | DTB | ATP-dependent dethiobiotin synthetase BioD | / | 0.441 | |
| 3my5 | RFZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.441 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.441 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.441 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.441 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4bi1 | ZO6 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.441 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4cs0 | ACO | PanD regulatory factor | / | 0.441 | |
| 4f4q | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.441 | |
| 4fko | 20K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4kqw | NAP | Ketol-acid reductoisomerase (NADP(+)) | / | 0.441 | |
| 4p6x | HCY | Glucocorticoid receptor | / | 0.441 | |
| 4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.441 | |
| 5hy5 | FAD | Tryptophan 6-halogenase | / | 0.441 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.440 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.440 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.440 | |
| 1pxl | CK4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1sqf | SAM | Ribosomal RNA small subunit methyltransferase B | 2.1.1.176 | 0.440 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 1u0h | ONM | Adenylate cyclase type 2 | / | 0.440 | |
| 1u0h | ONM | Adenylate cyclase type 5 | / | 0.440 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1z1f | STL | Resveratrol synthase | / | 0.440 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.440 | |
| 2exm | ZIP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.440 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.440 | |
| 2pkr | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.440 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.440 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.440 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.440 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.440 | |
| 2z2d | HSI | Macrophage metalloelastase | 3.4.24.65 | 0.440 | |
| 2zfn | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.440 | |
| 3abi | NAD | Uncharacterized protein | / | 0.440 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 3dej | RXC | Caspase-3 | 3.4.22.56 | 0.440 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.440 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.440 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.440 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 3qzg | X67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.440 | |
| 3r8v | Z62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3rou | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.440 | |
| 3s1a | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.440 | |
| 3sxn | COA | N-acetyltransferase Eis | / | 0.440 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.440 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.440 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.440 | |
| 3wbf | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.440 | |
| 4a7b | 3W5 | Collagenase 3 | 3.4.24 | 0.440 | |
| 4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.440 | |
| 4c3s | NAD | Aldehyde Dehydrogenase | / | 0.440 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.440 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4ifv | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4iqk | IQK | Kelch-like ECH-associated protein 1 | / | 0.440 | |
| 4mcv | 29K | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.440 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.440 | |
| 5av4 | GEN | Death-associated protein kinase 1 | 2.7.11.1 | 0.440 | |
| 5kj6 | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 |