sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2hl3 | GLU_GLU_TYR | Dynactin subunit 1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2hl3 | GLU_GLU_TYR | Dynactin subunit 1 | / | 1.000 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.514 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.512 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.506 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.502 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.502 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.499 | |
| 2ejz | SAH | Diphthine synthase | / | 0.498 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.497 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.495 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.493 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.491 | |
| 4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.491 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.489 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.487 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.487 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.487 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.486 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.485 | |
| 1mlv | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.484 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.483 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.482 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.480 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.480 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.480 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.480 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.479 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.479 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.479 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.479 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.478 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.478 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.477 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.477 | |
| 1yp4 | ADQ | Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic | 2.7.7.27 | 0.477 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.477 | |
| 3cd5 | 7HI | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.476 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.476 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.476 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.476 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.475 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.473 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.473 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.473 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.473 | |
| 4okw | 198 | Androgen receptor | / | 0.473 | |
| 4rel | KMP | Glycosyltransferase | / | 0.473 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.472 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.472 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.472 | |
| 4b1f | KRH | Glutamate racemase | / | 0.472 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.472 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.472 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.471 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.471 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.471 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.470 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.470 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.470 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.469 | |
| 1tg5 | 645 | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.469 | |
| 1vce | SAH | Diphthine synthase | / | 0.469 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.469 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.469 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.468 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 1z45 | UPG | Bifunctional protein GAL10 | 5.1.3.2 | 0.468 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.468 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.468 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.468 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.468 | |
| 4ira | FAD | 4-hydroxyphenylacetate 3-monooxygenase | / | 0.468 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.468 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.468 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.467 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.467 | |
| 3eku | CY9 | Actin-5C | / | 0.467 | |
| 3myk | ANP | Myosin-2 heavy chain | / | 0.467 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.467 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.467 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.467 | |
| 3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.467 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.467 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.467 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.466 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.466 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.466 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.466 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.466 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.466 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.466 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.466 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.466 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.465 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.465 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.465 | |
| 4okb | 198 | Androgen receptor | / | 0.465 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.464 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.464 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.464 | |
| 1og4 | NAI | T-cell ecto-ADP-ribosyltransferase 2 | / | 0.464 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.464 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.464 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.464 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.464 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.464 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.463 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.463 | |
| 2vo4 | GTB | 2,4-D inducible glutathione S-transferase | / | 0.463 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.463 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.463 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.463 | |
| 3gqo | APR | Non-structural polyprotein | / | 0.463 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.463 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.463 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.463 | |
| 4rrq | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.463 | |
| 1fml | RTL | Retinol dehydratase | / | 0.462 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.462 | |
| 1orh | SAH | Protein arginine N-methyltransferase 1 | / | 0.462 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.462 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.462 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.462 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.462 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.462 | |
| 3t3i | GPW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.462 | |
| 4in4 | 4ID | Kelch-like ECH-associated protein 1 | / | 0.462 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.462 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.462 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.462 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.462 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.462 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.461 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.461 | |
| 2owf | SAH | Diphthine synthase | / | 0.461 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.461 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.461 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.461 | |
| 4ceq | QCH | Integrase | / | 0.461 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.461 | |
| 4y1b | NAP | AntE | / | 0.461 | |
| 4y9u | NAP | NADPH--cytochrome P450 reductase | / | 0.461 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.460 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.460 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.460 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.460 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.460 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.460 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.460 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.460 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.460 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.460 | |
| 4okx | 198 | Androgen receptor | / | 0.460 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.460 | |
| 4rrc | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.460 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.460 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.460 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.459 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.459 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.459 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.459 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.459 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.459 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.459 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.459 | |
| 3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.459 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.459 | |
| 4j1t | NAP | NAD(P) transhydrogenase subunit beta | / | 0.459 | |
| 5alu | HD2 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.459 | |
| 5csh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.459 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.459 | |
| 1ppj | ANY | Cytochrome b | / | 0.458 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.458 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.458 | |
| 2z6j | TUI | 2-nitropropane dioxygenase | / | 0.458 | |
| 3dt2 | GTP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.458 | |
| 3wti | CT4 | Acetylcholine-binding protein | / | 0.458 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.458 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 4ple | CPS | Nuclear receptor subfamily 5 group A member 2 | / | 0.458 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.457 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.457 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.457 | |
| 1pw6 | FRB | Interleukin-2 | / | 0.457 | |
| 1svm | ATP | Large T antigen | 3.6.4 | 0.457 | |
| 1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.457 | |
| 2h23 | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.457 | |
| 2huv | SAH | Diphthine synthase | / | 0.457 | |
| 2pvk | P45 | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.457 | |
| 3at3 | ATK | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.457 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.457 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.457 | |
| 3ihz | FK5 | Peptidylprolyl isomerase | / | 0.457 | |
| 3rqq | BA3 | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.457 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.457 | |
| 3wff | WFF | Mineralocorticoid receptor | / | 0.457 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.457 | |
| 4boe | CLR | Japanin | / | 0.457 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.457 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.457 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.456 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1r2j | FAD | FkbI | / | 0.456 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.456 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.456 | |
| 2vnj | FAD | NADPH:ferredoxin reductase | / | 0.456 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.456 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.456 | |
| 3oxf | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.456 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.456 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.456 | |
| 4a9o | A9O | Bromodomain-containing protein 2 | / | 0.456 | |
| 4ba5 | PXG | Probable aminotransferase | / | 0.456 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.456 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.456 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.456 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.456 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.455 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.455 | |
| 1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.455 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.455 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.455 | |
| 2xvv | 9DN | Serum albumin | / | 0.455 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.455 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.455 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.455 | |
| 3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.455 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.455 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.455 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.455 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.455 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.455 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4e2b | FMN | Dehydrogenase | / | 0.455 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.455 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.455 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.455 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.454 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.454 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.454 | |
| 2bpo | NAP | NADPH--cytochrome P450 reductase | / | 0.454 | |
| 2c4j | GSO | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.454 | |
| 2e08 | SAH | Diphthine synthase | / | 0.454 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.454 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.454 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.454 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.454 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.454 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.454 | |
| 3fvq | ATP | Fe(3+) ions import ATP-binding protein FbpC | / | 0.454 | |
| 3gdv | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.454 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.454 | |
| 4k7y | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.454 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.454 | |
| 4yqf | GDP | Septin-9 | / | 0.454 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.453 | |
| 2r9e | SDX | Citrate synthase | 2.3.3.16 | 0.453 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.453 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4avl | TMP | Polymerase acidic protein | / | 0.453 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.453 | |
| 4j0s | 1H3 | Bromodomain-containing protein 4 | / | 0.453 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.453 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.452 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1z95 | 198 | Androgen receptor | / | 0.452 | |
| 2bxm | IMN | Serum albumin | / | 0.452 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.452 | |
| 2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.452 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.452 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.452 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.452 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.452 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.452 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.452 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.452 | |
| 4cjp | 4D2 | Integrase | / | 0.452 | |
| 4fi1 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.452 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.452 | |
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.452 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.452 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.452 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.452 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.451 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.451 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.451 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.451 | |
| 2imp | NAI | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.451 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.451 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.451 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.451 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.451 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.451 | |
| 3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.451 | |
| 3uu1 | 14B | Anthranilate phosphoribosyltransferase | / | 0.451 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.451 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4dij | BLF | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.451 | |
| 4rrd | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.451 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.451 | |
| 4u7w | NDP | MxaA | / | 0.451 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.451 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.450 | |
| 1ewy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.450 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.450 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.450 | |
| 1u1j | C2F | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 | 2.1.1.14 | 0.450 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.450 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.450 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.450 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 3cse | N22 | Uncharacterized protein | / | 0.450 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.450 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.450 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.450 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.450 | |
| 4j16 | NAP | NAD(P) transhydrogenase subunit beta | / | 0.450 | |
| 4j1p | 1K0 | Bromodomain-containing protein 2 | / | 0.450 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.450 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.450 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.450 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.450 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.449 | |
| 1mma | ADP | Myosin-2 heavy chain | / | 0.449 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.449 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.449 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.449 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.449 | |
| 2xnc | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.449 | |
| 2xvu | 9DN | Serum albumin | / | 0.449 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.449 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.449 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.449 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.449 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.449 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.449 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.449 | |
| 4h6p | FMN | Chromate reductase | / | 0.449 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.449 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.449 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1gjr | NAP | Ferredoxin--NADP reductase | 1.18.1.2 | 0.448 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.448 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.448 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.448 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.448 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.448 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.448 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.448 | |
| 3qft | NAP | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.448 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.448 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.448 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.448 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.448 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.448 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.447 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.447 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.447 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.447 | |
| 2egb | SAH | Diphthine synthase | / | 0.447 | |
| 2ehl | SAH | Diphthine synthase | / | 0.447 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.447 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.447 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.447 | |
| 2uup | LK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.447 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.447 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.447 | |
| 3lki | ATP | Fructokinase | / | 0.447 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.447 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.447 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.447 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.447 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.447 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 4lb2 | DM5 | Serum albumin | / | 0.447 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.447 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.446 | |
| 1xve | 3BB | Methane monooxygenase component A beta chain | 1.14.13.25 | 0.446 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.446 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.446 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.446 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.446 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.446 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.446 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.446 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.446 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.446 | |
| 4b42 | 942 | Glucose-1-phosphate thymidylyltransferase | / | 0.446 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4l7v | SAH | Protein-L-isoaspartate O-methyltransferase | / | 0.446 | |
| 4odo | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.446 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.446 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.446 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 5egh | PC | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 | / | 0.446 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.445 | |
| 1eio | GCH | Gastrotropin | / | 0.445 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.445 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.445 | |
| 1q65 | BHB | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.445 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.445 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.445 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2qhw | PZZ | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.445 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.445 | |
| 2ylt | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.445 | |
| 3awh | FMN | FMN-binding protein | / | 0.445 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.445 | |
| 3b9l | AZZ | Serum albumin | / | 0.445 | |
| 3dv0 | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.445 | |
| 3dv0 | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.445 | |
| 3e8x | NAP | BH1520 protein | / | 0.445 | |
| 3g11 | P9C | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.445 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.445 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.445 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.445 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.445 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.445 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 4gnc | ASO | Regucalcin | 3.1.1.17 | 0.445 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.445 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.445 | |
| 4j7u | YTZ | Sepiapterin reductase | 1.1.1.153 | 0.445 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.445 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.445 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.444 | |
| 1bjk | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 1khr | VIR | Streptogramin A acetyltransferase | 2.3.1 | 0.444 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 1luq | BTN | Streptavidin | / | 0.444 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.444 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.444 | |
| 2bn4 | NAP | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.444 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.444 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.444 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 2vtb | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.444 | |
| 2wgg | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.444 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.444 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.444 | |
| 3g8d | ADP | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.444 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.444 | |
| 3owu | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.444 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.444 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.444 | |
| 4apu | A2K | Progesterone receptor | / | 0.444 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.444 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.444 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.444 | |
| 4kb8 | 1QO | Casein kinase I isoform delta | 2.7.11.1 | 0.444 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 4olf | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.444 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4pb2 | 5UD | Nucleoside permease | / | 0.444 | |
| 4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.444 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.444 | |
| 4yfy | 1YJ | VioF | / | 0.444 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.443 | |
| 1cne | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.443 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.443 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.443 | |
| 1g0r | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.443 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.443 | |
| 1srf | MTB | Streptavidin | / | 0.443 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.443 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.443 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.443 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.443 | |
| 2emr | SAH | Diphthine synthase | / | 0.443 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.443 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.443 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.443 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.443 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.443 | |
| 2k5t | COA | PanD regulatory factor | / | 0.443 | |
| 2op9 | WR1 | Orf1ab polyprotein | / | 0.443 | |
| 2r26 | CMC | Citrate synthase | 2.3.3.16 | 0.443 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.443 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.443 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.443 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.443 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.443 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.443 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 4cf2 | 3GM | Integrase | / | 0.443 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.443 | |
| 4xcz | FON | Qdtf | / | 0.443 | |
| 5djt | FMN | NPH1-2 | / | 0.443 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.442 | |
| 1g41 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.442 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.442 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.442 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.442 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.442 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2cah | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.442 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.442 | |
| 3bhr | THG | Thymidylate synthase | / | 0.442 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 3er9 | 3AT | Poly(A) polymerase catalytic subunit | 2.7.7.19 | 0.442 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.442 | |
| 3qfs | NAP | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.442 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 4d9f | DCS | D-cysteine desulfhydrase | / | 0.442 | |
| 4ebf | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.442 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.442 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.442 | |
| 4hi0 | GDP | Urease accessory protein UreG | / | 0.442 | |
| 4i0j | 842 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.442 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 4ok1 | 198 | Androgen receptor | / | 0.442 | |
| 4qxm | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4rr9 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.442 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.442 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.442 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.442 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.442 | |
| 5b0o | ADP | Flagellum-specific ATP synthase | 3.6.3.14 | 0.442 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.441 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.441 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.441 | |
| 1fnc | FDA | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.441 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
| 1sqi | 869 | 4-hydroxyphenylpyruvate dioxygenase | / | 0.441 | |
| 1stp | BTN | Streptavidin | / | 0.441 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.441 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.441 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2bf4 | NAP | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 2e8h | SAH | Diphthine synthase | / | 0.441 | |
| 2egl | SAH | Diphthine synthase | / | 0.441 | |
| 2kce | D16 | Thymidylate synthase | / | 0.441 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.441 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.441 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.441 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.441 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.441 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.441 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.441 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.441 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.441 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 3v4a | PK1 | Androgen receptor | / | 0.441 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.441 | |
| 4bw1 | S5B | Bromodomain-containing protein 4 | / | 0.441 | |
| 4bw3 | 9BM | Bromodomain-containing protein 4 | / | 0.441 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.441 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.441 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.441 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.441 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.441 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.441 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 5dbv | COA | Aldehyde Dehydrogenase | / | 0.441 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.441 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.440 | |
| 1g9c | BAB | Botulinum neurotoxin type B | 3.4.24.69 | 0.440 | |
| 1gti | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.440 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.440 | |
| 1ppl | 1Z7 | Penicillopepsin-1 | 3.4.23.20 | 0.440 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.440 | |
| 2eld | SAH | Diphthine synthase | / | 0.440 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.440 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.440 | |
| 2fto | TMP | Thymidylate synthase | / | 0.440 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.440 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.440 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.440 | |
| 2jfz | 003 | Glutamate racemase | / | 0.440 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 2rti | GLL | Streptavidin | / | 0.440 | |
| 2uxi | G50 | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.440 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 3eks | CY9 | Actin-5C | / | 0.440 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.440 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 3lzx | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.440 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.440 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.440 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.440 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.440 | |
| 4gm4 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.440 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.440 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.440 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 4olm | 198 | Androgen receptor | / | 0.440 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.440 |