Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 1.000 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.649 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.642 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.628 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.609 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.606 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.600 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.589 | |
| 4ft9 | H4K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.588 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.587 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.586 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.583 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.583 | |
| 2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.580 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.580 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.579 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.578 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.573 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.570 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.570 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.561 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.557 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.557 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.556 | |
| 4fsm | HK1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.556 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.552 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.551 | |
| 4ft3 | H1K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.551 | |
| 4ftj | H8K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.551 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.549 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.548 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.548 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.546 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.545 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.542 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.540 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.540 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.538 | |
| 4fsy | HK7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.537 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.530 | |
| 2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.528 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.527 | |
| 2wms | ZYS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.526 | |
| 4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.526 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.522 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.520 | |
| 2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.520 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.517 | |
| 4fsu | HK5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.514 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.513 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.511 | |
| 1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.510 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.510 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.510 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.509 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.508 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.508 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.507 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.507 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.505 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.504 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.504 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.503 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.503 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.503 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.503 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.502 | |
| 2ym3 | YM3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.502 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.502 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.502 | |
| 2wmr | ZYR | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.501 | |
| 1zar | ADP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.500 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.500 | |
| 2wmw | ZYW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.499 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.498 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.498 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.498 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.497 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.496 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.496 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.496 | |
| 4ftq | 4HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.496 | |
| 2xbj | XBJ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.495 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.495 | |
| 4fta | H5K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.495 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.494 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.494 | |
| 2e9p | 77A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.494 | |
| 2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.494 | |
| 4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.494 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.493 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.491 | |
| 1ol6 | ATP | Aurora kinase A | 2.7.11.1 | 0.489 | |
| 2wmx | ZY6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.489 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.489 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.489 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.488 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.488 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.487 | |
| 3c4x | ATP | Rhodopsin kinase | / | 0.487 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.487 | |
| 4e93 | GUI | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.487 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.487 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.486 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.486 | |
| 4fx3 | 60K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.486 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.485 | |
| 2bkz | SBC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.485 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.485 | |
| 2wtc | VGM | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.485 | |
| 2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.484 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.484 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.483 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.483 | |
| 4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.483 | |
| 1tqp | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.482 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.482 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.482 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
| 2xne | ASH | Aurora kinase A | 2.7.11.1 | 0.481 | |
| 4gu9 | 4GU | Focal adhesion kinase 1 | 2.7.10.2 | 0.481 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.480 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.480 | |
| 2pe1 | 517 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.479 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.479 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.479 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.479 | |
| 4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.479 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.479 | |
| 1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.478 | |
| 1zlt | HYM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.478 | |
| 2ym8 | YM8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.478 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.478 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.478 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.478 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.478 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.477 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.477 | |
| 4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.477 | |
| 4gu6 | 10N | Focal adhesion kinase 1 | 2.7.10.2 | 0.477 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.477 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.476 | |
| 1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.476 | |
| 2gdo | 12C | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.476 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.476 | |
| 4fto | 3HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.476 | |
| 1oky | STU | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.475 | |
| 1tqm | ANP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.475 | |
| 3h3c | P1E | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.475 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.475 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.475 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.475 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.474 | |
| 3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.474 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.474 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.474 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.473 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.473 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
| 3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.473 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.473 | |
| 4ct1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.473 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.473 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.472 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.472 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.472 | |
| 2ydj | YDJ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.472 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.472 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.471 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.471 | |
| 3ll9 | ADP | Isopentenyl phosphate kinase | / | 0.471 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.471 | |
| 3uim | ANP | BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 | 2.7.10.1 | 0.471 | |
| 3vf9 | 477 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.471 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.471 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.471 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 1uu7 | BI2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.470 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.470 | |
| 2xm9 | LWH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.470 | |
| 4c57 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.470 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.470 | |
| 4k8a | K8A | Focal adhesion kinase 1 | 2.7.10.2 | 0.470 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 1unl | RRC | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.469 | |
| 1uvr | BI8 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.469 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.469 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 2xng | A0H | Aurora kinase A | 2.7.11.1 | 0.469 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.469 | |
| 3f7z | 34O | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.469 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.469 | |
| 4ftl | H0K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.468 | |
| 3a62 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.468 | |
| 3qcq | 3Q0 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.468 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.468 | |
| 4fst | HK4 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.468 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.468 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.467 | |
| 2wmv | ZYV | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.467 | |
| 5aux | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.467 | |
| 5cvc | PLP | Serine racemase | / | 0.467 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.466 | |
| 1vyw | 292 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.466 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.466 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 3wbb | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.466 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.466 | |
| 4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.466 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.466 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.465 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.465 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 2x6d | X6D | Aurora kinase A | 2.7.11.1 | 0.465 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.465 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.465 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.465 | |
| 4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.465 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.465 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.464 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 2jkk | BI9 | Focal adhesion kinase 1 | 2.7.10.2 | 0.464 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.464 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.464 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.464 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.464 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.464 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.463 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2oj9 | BMI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.463 | |
| 2qhn | 582 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.463 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 3gob | HXX | DdmC | / | 0.463 | |
| 3h4l | ANP | DNA mismatch repair protein PMS1 | / | 0.463 | |
| 3tm0 | ANP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.463 | |
| 3zm4 | 22T | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.463 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.463 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.463 | |
| 5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.463 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.462 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.462 | |
| 2vgo | AD5 | Aurora kinase B-A | 2.7.11.1 | 0.462 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.462 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.462 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.462 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.462 | |
| 4yqf | GDP | Septin-9 | / | 0.462 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.462 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.462 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.461 | |
| 1q19 | SSC | Carbapenam-3-carboxylate synthase | 6.3.3.6 | 0.461 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.461 | |
| 2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.461 | |
| 3et7 | 349 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.461 | |
| 3gu6 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.461 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.461 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.461 | |
| 4krc | AGS | Cyclin-dependent protein kinase PHO85 | 2.7.11.22 | 0.461 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.461 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1npa | 3NH | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1npw | LGZ | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.460 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.460 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.460 | |
| 4l98 | LRG | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 4yhj | AN2 | G protein-coupled receptor kinase 4 | 2.7.11.16 | 0.460 | |
| 1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 1qy5 | NEC | Endoplasmin | / | 0.459 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.459 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.459 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.459 | |
| 3niz | ADP | Cdc2-like CDK2/CDC28 like protein kinase | / | 0.459 | |
| 4btj | ATP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.459 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.459 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.459 | |
| 4xx0 | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.459 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.458 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.458 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.458 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.458 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.458 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.458 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.457 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.457 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.457 | |
| 2y3s | TIR | TamL | / | 0.457 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.457 | |
| 3r7i | X9I | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.457 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.457 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.457 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.457 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.456 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.456 | |
| 1v0p | PVB | Cell division control protein 2 homolog | 2.7.11.22 | 0.456 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.456 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.456 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.456 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.456 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.456 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4j98 | ACP | Fibroblast growth factor receptor 2 | / | 0.456 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.456 | |
| 5auu | LU2 | Death-associated protein kinase 1 | 2.7.11.1 | 0.456 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.455 | |
| 1mp8 | ADP | Focal adhesion kinase 1 | 2.7.10.2 | 0.455 | |
| 1phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.455 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.455 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.455 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.455 | |
| 5auv | AGI | Death-associated protein kinase 1 | 2.7.11.1 | 0.455 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.454 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.454 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 3ig7 | EFP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4fkl | CK2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4fl1 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.454 | |
| 4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 4ftn | 2HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.454 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.454 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.454 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 5e92 | ANP | TGF-beta receptor type-2 | 2.7.11.30 | 0.454 | |
| 1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1zao | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.453 | |
| 2biy | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.453 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.453 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.453 | |
| 2ydk | YDK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2yex | YEX | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.453 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.453 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.453 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.453 | |
| 3w55 | 1FM | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.453 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.453 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.453 | |
| 4i4e | 1BQ | Focal adhesion kinase 1 | 2.7.10.2 | 0.453 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.453 | |
| 4l3j | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.453 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.453 | |
| 4w9w | YDJ | BMP-2-inducible protein kinase | 2.7.11.1 | 0.453 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.453 | |
| 5av2 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.453 | |
| 1e7a | PFL | Serum albumin | / | 0.452 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.452 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.452 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.452 | |
| 2b9j | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.452 | |
| 2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.452 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.452 | |
| 2vuw | 5ID | Serine/threonine-protein kinase haspin | 2.7.11.1 | 0.452 | |
| 3eko | PYU | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3h65 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.452 | |
| 3nuy | JPZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 4gfo | 0X2 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.452 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.452 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.451 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.451 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.451 | |
| 3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.451 | |
| 3w0s | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.451 | |
| 3wi6 | YRZ | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.451 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.451 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.451 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.451 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.451 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.450 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 1xny | 191 | Propionyl-CoA carboxylase complex B subunit | / | 0.450 | |
| 2zno | S44 | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 3c4z | ADP | Rhodopsin kinase | / | 0.450 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.450 | |
| 4b8l | A0P | Aurora kinase B-A | 2.7.11.1 | 0.450 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 4ysj | ADP | Calmodulin-like domain protein kinase | / | 0.450 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.449 | |
| 1q8u | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 1qmz | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1snu | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.449 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.449 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 2oji | 33A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.449 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3fzp | AGS | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.449 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.449 | |
| 4brx | KGW | Focal adhesion kinase 1 | 2.7.10.2 | 0.449 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.449 | |
| 4n9w | GDP | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.449 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.449 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.448 | |
| 1nxk | STU | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.448 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.448 | |
| 1t7k | BH0 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1wbs | LI2 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.448 | |
| 2c6d | ANP | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 2vwy | 7X5 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.448 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.448 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.448 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.448 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.448 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 4iva | 1J5 | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.448 | |
| 4req | 5AD | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.448 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.448 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.447 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.447 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.447 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.447 | |
| 2jkq | VG8 | Focal adhesion kinase 1 | 2.7.10.2 | 0.447 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.447 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.447 | |
| 3q9w | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 3qyw | 6PB | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 4ccb | OFG | ALK tyrosine kinase receptor | 2.7.10.1 | 0.447 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.447 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.447 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.447 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.447 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.446 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.446 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2eva | ADN | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.446 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.446 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.446 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.446 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.446 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.446 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.446 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.446 | |
| 3bhy | 7CP | Death-associated protein kinase 3 | / | 0.446 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.446 | |
| 3d7t | STU | Tyrosine-protein kinase CSK | / | 0.446 | |
| 3u9e | COA | Lmo1369 protein | / | 0.446 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.446 | |
| 4fl3 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.446 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.446 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.446 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 1uyr | D1L | Acetyl-CoA carboxylase | / | 0.445 | |
| 2bhh | RYU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2py7 | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.445 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.445 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.445 | |
| 3c4w | ATP | Rhodopsin kinase | / | 0.445 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.445 | |
| 3fzr | 3JZ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.445 | |
| 3pvw | QRX | Beta-adrenergic receptor kinase 1 | 2.7.11.15 | 0.445 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.445 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.445 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.445 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.445 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.445 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.445 | |
| 5c8d | 5AD | Probable transcriptional regulator | / | 0.445 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 1j7l | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.444 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.444 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 2gqp | PA7 | Endoplasmin | / | 0.444 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 3bgc | LJH | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3r7e | X88 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.444 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.444 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.444 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.443 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.443 | |
| 1q4l | 679 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2gfd | RDA | Endoplasmin | / | 0.443 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2ijm | ADP | Focal adhesion kinase 1 | 2.7.10.2 | 0.443 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.443 | |
| 2x2l | X2L | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.443 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.443 | |
| 3gb2 | G3B | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.443 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.443 | |
| 3qih | FG7 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3zmm | F9J | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 4c35 | NU3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 4f70 | 0ST | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.443 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.443 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 4l8u | 9AZ | Serum albumin | / | 0.443 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.442 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2cn8 | DBQ | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.442 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.442 | |
| 2vtj | LZ4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 3kkv | B99 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 3m42 | HGF | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.442 | |
| 3tnw | F18 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.442 | |
| 4b42 | 942 | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 4ct2 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 4eom | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 4gyi | ADP | Uncharacterized protein | / | 0.442 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.442 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.442 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.442 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1efa | NPF | Lactose operon repressor | / | 0.441 | |
| 1kvt | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1kzk | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 2pml | ANP | Uncharacterized protein | / | 0.441 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2vag | V25 | Dual specificity protein kinase CLK1 | 2.7.12.1 | 0.441 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 3ama | SKE | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 3b89 | 5GP | 16S rRNA methylase | / | 0.441 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.441 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.441 | |
| 3qc9 | ADP | Rhodopsin kinase | / | 0.441 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3uow | XMP | GMP synthase [glutamine-hydrolyzing] | / | 0.441 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.441 | |
| 4agu | D15 | Cyclin-dependent kinase-like 1 | / | 0.441 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.441 | |
| 4jbp | YPH | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.441 | |
| 1c6y | MK1 | Protease | / | 0.440 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.440 | |
| 1ke6 | LS2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.440 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 2xvv | 9DN | Serum albumin | / | 0.440 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3bkb | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.440 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3vet | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.440 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.440 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 3zuy | TCH | Transporter | / | 0.440 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.440 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 4gte | MEF | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.440 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.440 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.440 | |
| 4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.440 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.440 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.440 |